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Talk:Osteoarthritis/Archive 3

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1777:
being "antioxidants" is suspect as baloney because herbal extracts perform as antioxidants only in a test tube, and iii) all the clinical studies reviewed in the two Nutrition Journal articles used - PMID 26728196 and PMID 26818459 (current refs #122, 124) - are primary, weak designs (Table 2 in the Grover study and Table 1 in the Oe study) mainly published in non-credible alt-med journals. Seemingly out of desire for content balance - because herbal products have received substantial attention as possible therapies for osteoarthritis - we retain the two reviews to mention herbals under some current use and further study. Particularly the hyaluronan analysis by Oe et al. is primary research and of little-to-no value. Why anyone with scientific training would think that orally taking hyaluronan (a digestible polysaccharide) to magically benefit knee cartilage is a mysterious failure of reasoning. --
1888:
tramadol use in osteoarthritis (i.e. prevalence, addiction prevalence, etc) and use of CBD and other cannabis products since I have seen about 1 in 5 patients report MJ/CBD use for their pain. Although MJ research is currently limited, it would be interesting to include under treatment options if possible. For the other edits, they were neutral but very ambiguous due to lack of evidence for/against surgery and for/against certain lifestyles. Since there is a lack of evidence for/against each side, these edits could be improved by including debated pros/cons of surgery to help improve the article. Otherwise, I really like the groups' goals for this article since it’s a huge area of treatment.
256:, ok. I'm really not understanding why you seem to have deleted the SKI 306X page. It sure makes much more sense to put that whole paragraph you have there on a separate SKI 306X page. Same for ASU. Shouldn't week keep the OA page short and link to a separate page for every medicine? Keep them equal? I stonrly suggest moving all of the ASU and SKI 306 info to a dedicated page. SAMe is a much more common supplement than either of those two and if SAMe only gets one word in the article, then surely these two only deserve one word. Otherwise we need to put, at least, one long paragraph for SAMe. 1910:
to address tramadol as their second goal but it was removed by another user. It appears as though primary sources were used but finding reviews would be a great next step in solidifying this as a treatment option. The group made an effort to touch upon their goals and I think with more time would have been easily able to achieve them in totality. Their edits are all within the framework of Knowledge's manual of style and are sure to use the proper capitalization, punctuation, and grammar in addition to proper formatting in source citation within the text.
1455:
1966, 1976, 1985, 2001, 2009(x2), 2011(x3), 2012(x2), and 2013(x2). So clearly the date of a reference can not simply be used as a reason to remove a reference, unless we wan't to remove a vast majority of references in the whole article. We can also ignore #1 as the topic at hand is alternative medicines. That only leaves #2 predatory. Ok, so we just need to list the journals and see if all articles from these journals should be removed from Knowledge sitewide. Here are some of the journals:
31: 426:, I'm curious where you are planning to go with the updates you are making. How is a discussion about "society and culture" relevant to a particular medication for the management of OA? Why such a large emphcasis on two random treatment options? You have said that you will update soon, so I will give you time to make it clear. Maybe you plan to make equivalent expansions for all of the listed medications. 932:
some evidence that these programs may slightly decrease pain, improve function, reduce stiffness and fatigue, and reduce medical usage. Clinical practice guidelines released by the American Physical Therapy Association, indicate that educational programs can provide on average 20% more pain relief when compared to NSAIDs alone in patients with hip osteoarthritis.
349:, would you provide an opinion on Jytdog's expansion of ASU, SKI 306X, and phytodolor? The information he is adding is interesting and would go great on dedicated pages for each of those medications, and is not relevant to OA. Can we please put all this information on a dedicated page for each medicine and return the OA page to the way it was? 2147: 926:
help me tackle this? I do not have the experience in the field to understand the conflicting viewpoints and know what the present clinical guidelines are. My next step is to review the 2009 citation that is presently in the article and verify the conclusions (to understand where the 20% is coming from) Here is what I have so far:
931:
For overweight people, weight loss may be an important factor. Education may be helpful in the self-management of arthritis, however, a 2014 Cochrane systematic review found that there is no strong evidence that self-management programs have a clinical benefit for people with osteoarthritis. There is
1820:
Cochrane review: Toupin April, Karine; Bisaillon, Jacinthe; Welch, Vivian; Maxwell, Lara J; Jüni, Peter; Rutjes, Anne WS; Husni, M Elaine; Vincent, Jennifer; El Hindi, Tania (2019-05-27). "Tramadol for osteoarthritis". Cochrane Database of Systematic Reviews. doi:10.1002/14651858.cd005522.pub3. ISSN
1086:
This reference: Rutjes AW, Nüesch E, Reichenbach S, Jüni P (October 2009). "S-Adenosylmethionine for osteoarthritis of the knee or hip" (PDF). The Cochrane Database of Systematic Reviews (4): CD007321. doi:10.1002/14651858.CD007321.pub2. PMID 19821403., is from 2009 so it is reviewing articles from
1909:
The groups first goal about addressing treatment options wasn't elaborated on because of the information and citations already provided and matching their research. It's a very fleshed out section in the article and covers a wide variety of treatments with strong pieces of evidence. The group chose
548:
are diametrically opposed as defined by wiki. Phytotherapy = "science-based medical practice", Alternative medicine="disproven, unproven, impossible to prove, or only harmful". The treatments listed are supported by review articles, they are definitely not disproven, unproven, impossible to prove
1454:
Let's approach this systematically. I think you are making three objections 1) Alternative medicine, 2) Predatory, and 3) Outdated. We can just throw out #3. Just looking at the first 30 references of the article, 43% of them are from before 2014, with the oldest from 1966. Here are the dates:
1776:
Let's just say that i) any article in Nutrition Journal about a clinical condition like osteoarthritis should raise suspicion about quality of the underlying clinical research (clinical authors with solid reviews wouldn't publish there), ii) any discussion about dietary or topical herbal remedies
925:
Hello, I am updating this article with a few Cochrane reviews. I was planning to share a 2014 Cochrane Review looking at the efficacy of self-management education programs. It conflicts with a 2009 clinical practice guideline released by the American Physiotherapy Association. Does anyone want to
1887:
Unfortunately, Jane’s edits were removed and Jane’s edits were the one that addressed the groups goals so continuing to find better review articles on the pharmacological treatment of osteoarthritis will be important. If you need help refining your search, I would suggest expanding on opioid and
1167:
The point is not about high quality evidence. The first sentence is already qualified as "may be effective". The contentious point is the qualification of "not advised" which is only supported by the old review and there are 3 earlier reviews that disagree. Furthermore, the sentence is out of
691:
An IP user added this content and references. The "drugs" are actually candidate therapeutics not yet completed through the approval process, i.e., they may or may not prove to be effective and safe. This is primary research and inaccurately forecasts potential efficacy, making the content and
2062:
It is not exactly accurate to list Primary and Secondary OA under the "Risk Factors" heading. Primary vs secondary is a way to classify OA (although a bit of an artificial distinction) so risk factors should probably be its own section. Opening it up for discussion before taking a stab at it.
1317:
Doc James, thank you for the update. I have kept all references with my edit. I just moved all of the SAMe information into one area. There is no need to further highlight the 2010 reference, although it is still included there as another supporting evidence for "may be effective". I just
204:
3) Undue emphasis for ASU and SKI 306X - I completely understand why we have a long paragraph for glucosamine and even for chondroitin. Having such a long paragraph for ASU seem like undue weight. Same for SKI 306X. The previous sentence with no undue emphasis seems fair. As you are a more
1436:
These references have been extensively debated on this talk page, so if you want to re-open the discussion, then get consensus here before making such a huge change. We can go through each reference one by one, because this has already been done and consensus has been to accept them as they
1116:
I looked again and it looks like the reversion was done without carefully checking the edit. The 2016 article is still included and moved to above next to SAME. As already stated. The other one that was removed was the 2009 review, which is the only one that says "not advised". The 2016
88:
as "gum resin extracted from a tree", sounds like it is equivalent to the words "syrup", "resin" or "amber". It seems there is something confusing about boswellia serrata because on the above page, as well as the linked, Knowledge page, I can't find any consistency to the capitalization and
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2) Promoting commercial brands - ASU is a product available from many manufacturers and there is no good reason to believe that only the one brand name added is necessary. The SKI 360 is already a brand name and there is no need to specify any information about the manufactuer.
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please provide sources for other brands of ASU. I looked and didn't find any; maybe i missed something. it is common as dirt that we mention brand names in the only place where a product is discussed in WP, but if there are actually tons of them then yes we can omit the brand.
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1) Pushing vegetarian/vegan agenda - It seems irrelevant to the topic of osteoarthritis, the source of glucosamin, chondroitin, as well as the other medications. For those of su interested, we can go to the detailed page of each and no need to clutter up this article.
1496:
A Google search of each of these journals along with the term predatory returns zero results, except for "International journal of molecular sciences" which is a favorable discussion that it is not predatory. Please provide evidence that any of these journals are
1943:
The group has added additional information on some of the conflicting viewpoints regarding osteoarthritis which gives readers additional information to consider. The group has also added references which helps validate the information listed in the article.
1391:
already steps outside the quality expected to justify discussion of potential therapies, as most clinical studies were inconclusive or poorly designed. Only Cochrane reviews or similar quality sources and herbs should be discussed in this section.
1407:
This edit, has removed 10+ references and 6 treatments. Many of these review articles have been reviewed for years and discussed at length. It also is inconsistent as the Silva2011 reference is still included, yet it's support for phytodolor is
969:"Hip pain and mobility deficits--hip osteoarthritis: clinical practice guidelines linked to the international classification of functioning, disability, and health from the orthopaedic section of the American Physical Therapy Association" 1984:
Toupin April, Karine; Bisaillon, Jacinthe; Welch, Vivian; Maxwell, Lara J; Jüni, Peter; Rutjes, Anne WS; Husni, M Elaine; Vincent, Jennifer; El Hindi, Tania; Wells, George A; Tugwell, Peter (27 May 2019). "Tramadol for osteoarthritis".
1168:
place as sAME is already included and reference above with a weak qualification and 3 supporting references. I take issue with the "not advised" and with the extra sentence, and the 10 year old reference. Make sense?
1862:
Thank you. I'm going to add the above reference to the following sentence, "This is due to their small benefit and relatively large risk of side effects," since it seems that this updated Cochrane review supports this
382:, which seems to be an opinion paper by a single author being considered reliable when double-blind, placebo controlled trials with multiple authors are rejected until there is a meta-analysis of multiple such trials? 1248:
All of the reviews seem to agree that sAME is safe. They all seem to agree with the first sentence referencing sAME that says "may be effective". The justification for my edit was for these 3 reasons:
220:
your "concerns" about agendas are made-up bullshit. this and related articles got all fucked up recently and am fixing it. will finish tomorrow and you can see what the finished thing looks like.
1681:
Sanders M, Grundmann O (September 2011). "The use of glucosamine, devil's claw (Harpagophytum procumbens), and acupuncture as complementary and alternative treatments for osteoarthritis".
616:"practices not widely accepted by evidence-based medicine, even if there does exist evidence or the effects of the medicine is disproven, unproven, impossible to prove, or only harmful." 1761:
Thank you both for the discussion. For 'Nutrition Journal' there are two PMID, both listed as 'Review' articles. Which is primary research and why is it listed as a review? Thanks.
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which should make it clear they are not for human use and currently undergoing studies. I think a list of experimental drugs should be ok as we have lists of other experiments e.g.
897: 401:. We don't use primary sources (ones that describe any kind of experimental work including a clinical trial) to support content that is biomedical information. Please read 2078:
Good point. This whole section is on causes, not risk factors, as evidenced by the first sentence. I will change section title and see how you and others respond. Regards,
1950:
The group needs to address additional information regarding pharmacological therapy and medications. There was also no additional information listed regarding Tramadol.
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Cibulka, Michael T.; White, Douglas M.; Woehrle, Judith; Harris-Hayes, Marcie; Enseki, Keelan; Fagerson, Timothy L.; Slover, James; Godges, Joseph J. (April 2009).
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FYI, the other reference is still included after SAME above and it does not agree with the assessment of "not advised" and instead agrees with the above statement.
823: 1742:
Rosenbaum CC, O'Mathúna DP, Chavez M, Shields K (2010). "Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis".
1711: 613:"practices claimed to have the healing effects of medicine but are disproven, unproven, impossible to prove, or only harmful." to something more neutral like 549:
or only harmful. They definitely are science-based. The alt med label is a smear and phytotherapy is the accurate description. How am I misreading this?
1422:
It sounds like you are saying that any reference before 2014 should be removed and when I removed a 2009 reference it was reverted. How does that work?
1545:, where any one deficiency makes it questionable and removable under challenge: 1) whether the article is preliminary research or a quality review, 2) 735:
Adipoa, a join European development, coordinated in CHU of Montpellier by Christian Jorgensen, have completed Phase I, and could be available in 2020
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Invossa (TissueGene), has completed Phase III, is available in Korea, is claimed to be a DMOAD, and is targeted to be available in the US in 2023
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Kroon, Féline P. B.; van der Burg, Lennart R. A.; Buchbinder, Rachelle; Osborne, Richard H.; Johnston, Renea V.; Pitt, Veronica (2014-01-15).
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Remove characterization of "not be advised" because it is only mentioned in one 10 year old review and disagrees with more recent reviews.
1640: 1561:: the editor wishing to preserve challenged sources and content has the burden to convince others of the content and source quality. -- 2131: 1087:
earlier than this. There are much more recent reviews that don't agree with this assessment. Why do you think this is from 2016?
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That ref is supporting content that would fall under "society and culture" in a full article; it is not supporting content that is
1380: 398: 182:, I appreciate your attention to the Alternative Medicine section. The major re-writes are concerning to me for these reasons: 2154:: That's early-stage lab research and conjecture, many years from development as a testable concept or drug. Unencyclopedic. -- 2105: 2044: 1727: 1655: 1528: 1345: 1304: 1154: 647: 578: 519: 485: 1620: 1117:
reference does not agree with that conclusion, therefore no need to have a separate sentence specifically highlighting SAME.
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There are currently (fall 2017) no DMOADs, however there are currently several drugs in clinical trial for that indication.
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Do the group’s edits substantially improve the article as described in the Knowledge peer review “Guiding framework”?
2025:
3) This is unclear "The most commonly involved joints are the two joints in the fingers" as there are three joints.
1956:
Yes, all edits included appropriate citations to freely available articles that fall under Knowledge's guidelines.
142:, seems to explain that the correct style is 'First word only capitalized, italics' always. Let's head on over to 38: 1511:
We use the most recent high quality sources. Claims about pomegranate are so poor they should not be included per
1288:
Cochrane is a very good source. This is a not heavily researched topic area. We do not have newer better reviews.
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Alt med is not "disproven, unproven, impossible to prove, or only harmful" Some alt med is partly evidence based
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Is the position that no articles from any of these journals may be used anywhere on the medical Knowledge pages?
2012: 1958: 277:, I'd be interested to learn more what is so "fucked up" about this and related pages because I don't see it. 1846: 2135: 1953:
Are the points included verifiable with cited secondary sources that are freely available? If not, specify…
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Add up-to-date and relevant information about pharmacologic treatment options, including recent studies.
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Add up-to-date and relevant information about pharmacologic treatment options, including recent studies.
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Please add something on this topic because it appears these cells play significant role when treating.
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Zefr, thank you for the reply. I'm not following all of your points and we can just leave it there.
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List of drugs should likely not go in this article as they are indeed experimental. I've made
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Note that you can use the cite drop down menu to have Knowledge add a reference, like so.
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Factors for judging quality and reliability for the above list of publications used in
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simplified the Cochrane review sentence a little bit, keeping the spirit and reference.
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Remove unneccessary sentence highlighting one treatment when it is already mentioned
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and do a consistency check. Having learned something new, now the day is complete.
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The opinion of one author versus secondary/tertiary reviews with multiple authors
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italicization of the word because I find all of these combinations on the pages:
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If you wish to start a new discussion or revive an old one, please do so on the
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Hip and knee OA - NSAID works but safety concerns, paracetamol alone useless
598:, if that is true, then will you support a re-write of the intro sentence of 2155: 1778: 1562: 1393: 984: 697: 205:
experienced editor, I request your response before I undo these new changes.
1754: 1693: 1600: 1515:. There are multiple issues with the claim including no studies in humans. 1234: 1224: 1214: 1204: 1062: 1007: 848: 379: 1207:= no difference with COX-2 inhibitor NSAID, ignores 2010 & 2012 data 824:"Tout savoir sur l'arthrose #4 : les cellules souches contre l'arthrose" 2011:
1) This makes no sense / is wrong "The formation of hard knobs at the
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SM04690, (Samumed), Wnt inhibitor, has completed Phase II (Jul 2017)
1549:, 3) presence on lists for scam/predatory publishers, cataloged as 472:
Looking in more detail. Have restored as I misread the abstract.
124:. What is the logic of the conflicting style usage of this word? 112:
I'm pretty sure people put maple syrup on pancakes as opposed to
2022:
2) This has no reference "In many cases, the cause is unknown."
1388: 753:"Disease-Modifying Osteoarthritis Tx Granted Fast Track Status" 1817:
Add information about efficacy of tramadol in osteoarthritis:
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Add information about efficacy of tramadol in osteoarthritis:
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Do you have evidence that high quality evidence now supports
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First word only capitalized, no italics (middle of sentence)
1237:= "may be potentially clinically relevant" "not be advised" 1947:
Has the group achieved its overall goals for improvement?
1037:"Self-management education programmes for osteoarthritis" 102:
First word only capitalized, italics (middle of sentence)
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Foundations 2 2019, Group 8b Peer Review (8C), Francesca
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Remove 10 year old review when there are 3 earlier ones.
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self-management educational treatment approaches Comment
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User_talk:Doc_James#Current_Drug_Targets_Osteoarthritis
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The Journal of Orthopaedic and Sports Physical Therapy
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032142/
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Draft:Disease-modifying_Osteoarthritis_Drug_(DMOAD)
1883:Foundations 2 2019, Group 8c peer review, Vivian 1131:No new high quality studies per the 2016 review 874:"Adipoa-2 – Stem cell research for joint health" 696:and unencyclopedic, leading to their removal. -- 1557:(within 5 years, depending on quality), and 5) 1905:Foundations 2 2019, Group 8C peer review, Mehr 1619:Alternative Therapies in Health and Medicine: 1189:, ok let me try and lay this out more clearly: 1607:International journal of molecular sciences: 962: 960: 958: 8: 1744:Alternative Therapies in Health and Medicine 1712:Alternative Therapies in Health and Medicine 1477:Alternative Therapies in Health and Medicine 1471:International journal of molecular sciences 1041:The Cochrane Database of Systematic Reviews 405:and if you don't understand it please ask. 1375:was removed because the sources were from 157: 998: 1741: 1642:Making it not really a reliable source. 313:great ref, thanks. revised accordingly 1987:Cochrane Database of Systematic Reviews 1976: 1673: 1291:Add the conclusion from the other one. 954: 744: 444:"based on curcumin not curcumin itself" 84:The word 'boswellia serrata' described 1821:1465-1858. PMC 6536297. PMID 31132298. 1013: 44:Do not edit the contents of this page. 1227:= "effective in the management of OA" 634:Best to raise that discussion their. 7: 297:for alternative formulations of ASU. 2092:Happy with changing it to "causes" 192:Undue emphasis for ASU and SKI 306X 1809:Foundations 2 2019, Group 8b goals 1639:This has an impact factor of zero. 1593:Arthritis Research & Therapy: 105:Both words capitalized, no italics 24: 822:Demorand, Stéphane (2017-01-09). 670:doi:10.1016/S0140-6736(17)31744-0 2145: 1465:Arthritis Research & Therapy 29: 506:Does not need its own section. 186:Pushing vegetarian/vegan agenda 108:Both words capitalized, italics 1995:10.1002/14651858.cd005522.pub3 1049:10.1002/14651858.CD008963.pub2 726:, in Phase IIa as of Oct 2017. 80:Knowledge/Style - can of worms 1: 1581:Alternative Medicine Review: 1387:, before 2014) journals. The 902:List_of_experimental_aircraft 849:"ADIPOA - CHU de Montpellier" 436:08:59, 30 December 2016 (UTC) 415:07:46, 30 December 2016 (UTC) 392:07:43, 30 December 2016 (UTC) 359:07:54, 31 December 2016 (UTC) 327:07:19, 30 December 2016 (UTC) 307:06:56, 30 December 2016 (UTC) 287:02:18, 30 December 2016 (UTC) 266:02:15, 30 December 2016 (UTC) 245:02:09, 30 December 2016 (UTC) 230:02:06, 30 December 2016 (UTC) 215:01:57, 30 December 2016 (UTC) 164:00:23, 29 December 2016 (UTC) 134:00:14, 29 December 2016 (UTC) 93:No capitalization, no italics 2164:14:46, 19 October 2019 (UTC) 2140:13:53, 19 October 2019 (UTC) 2114:07:26, 10 October 2019 (UTC) 1368:Herbal and predatory sources 945:18:39, 30 January 2018 (UTC) 916:05:06, 3 February 2020 (UTC) 706:14:35, 4 November 2017 (UTC) 2088:14:57, 9 October 2019 (UTC) 2073:13:55, 9 October 2019 (UTC) 2053:01:35, 9 October 2019 (UTC) 1683:Alternative Medicine Review 1459:Alternative Medicine Review 656:10:32, 4 January 2017 (UTC) 626:10:07, 4 January 2017 (UTC) 587:09:41, 4 January 2017 (UTC) 559:14:24, 3 January 2017 (UTC) 528:13:18, 3 January 2017 (UTC) 494:14:13, 2 January 2017 (UTC) 465:13:33, 2 January 2017 (UTC) 189:Promoting commercial brands 2179: 2013:near joints of the fingers 1967:16:53, 7 August 2019 (UTC) 1922:21:41, 5 August 2019 (UTC) 1900:21:16, 5 August 2019 (UTC) 1878:21:04, 1 August 2019 (UTC) 1801:05:26, 18 March 2019 (UTC) 1787:17:57, 16 March 2019 (UTC) 1771:17:04, 15 March 2019 (UTC) 1736:11:00, 15 March 2019 (UTC) 1664:10:55, 15 March 2019 (UTC) 1571:14:18, 15 March 2019 (UTC) 1537:10:48, 15 March 2019 (UTC) 1507:03:59, 15 March 2019 (UTC) 1491:03:09, 15 March 2019 (UTC) 1447:02:55, 15 March 2019 (UTC) 1432:02:47, 15 March 2019 (UTC) 1418:02:40, 15 March 2019 (UTC) 1402:02:33, 15 March 2019 (UTC) 1354:09:26, 14 March 2019 (UTC) 1328:08:32, 14 March 2019 (UTC) 1313:08:17, 14 March 2019 (UTC) 1279:02:19, 14 March 2019 (UTC) 1178:09:53, 11 March 2019 (UTC) 1163:09:26, 11 March 2019 (UTC) 1127:08:06, 11 March 2019 (UTC) 1112:08:02, 11 March 2019 (UTC) 1097:07:59, 11 March 2019 (UTC) 1020:: CS1 maint: PMC format ( 96:No capitalization, italics 2130:is a relevant article. -- 1851:05:01, 31 July 2019 (UTC) 1836:21:18, 30 July 2019 (UTC) 399:WP:Biomedical information 171:Why such a major re-write 1389:"Other remedies" section 682:11:58, 7 July 2017 (UTC) 2058:Primary vs Secondary OA 985:10.2519/jospt.2009.0301 687:Drugs under development 502:Phytotherapy is alt med 1714:also is questionable. 1613:Current drug targets: 853:www.chu-montpellier.fr 455:, what does that mean? 293:FYI, please reference 1139:s-adenosyl methionine 724:cathepsin K inhibitor 140:Binomial nomenclature 42:of past discussions. 1474:Current drug targets 1377:alternative medicine 782:www.businesswire.com 600:Alternative Medicine 546:alternative medicine 1959:Francesca.alcala.96 1587:Nutrition Journal: 18:Talk:Osteoarthritis 1332:Okay sounds good. 1217:= "?" paid article 935:Thanks very much! 929:Lifestyle changes 375:, what is up with 120:, Maple Syrup, or 1629:More poor sources 1462:Nutrition Journal 679: 166: 145:Boswellia serrata 77: 76: 54: 53: 48:current talk page 2170: 2153: 2149: 2148: 2098: 2037: 2017:Bouchard's nodes 1999: 1998: 1981: 1861: 1758: 1720: 1698: 1697: 1678: 1648: 1589:primary research 1521: 1338: 1297: 1188: 1147: 1085: 1067: 1066: 1032: 1026: 1025: 1019: 1011: 1002: 964: 888: 887: 885: 884: 870: 864: 863: 861: 860: 845: 839: 838: 836: 835: 819: 813: 812: 810: 809: 798: 792: 791: 789: 788: 774: 768: 767: 765: 764: 749: 677: 640: 597: 571: 539: 512: 478: 454: 425: 374: 348: 276: 255: 181: 73: 56: 55: 33: 32: 26: 2178: 2177: 2173: 2172: 2171: 2169: 2168: 2167: 2146: 2144: 2124: 2122:Senescent cells 2094: 2060: 2033: 2009: 2004: 2003: 2002: 1983: 1982: 1978: 1929: 1907: 1885: 1855: 1811: 1716: 1708: 1703: 1702: 1701: 1680: 1679: 1675: 1644: 1631: 1595:outdated (2006) 1517: 1383:, or outdated ( 1370: 1334: 1293: 1269:Your thoughts? 1182: 1143: 1079: 1077: 1072: 1071: 1070: 1043:(1): 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Index

Talk:Osteoarthritis
archive
current talk page
Archive 1
Archive 2
Archive 3
here
Sthubbar
talk
00:14, 29 December 2016 (UTC)
Binomial nomenclature
Boswellia serrata
Sthubbar
talk
undated
00:23, 29 December 2016 (UTC)
Jytdog
Sthubbar
talk
01:57, 30 December 2016 (UTC)
Jytdog
talk
02:06, 30 December 2016 (UTC)
Jytdog
talk
02:09, 30 December 2016 (UTC)
Jytdog
Sthubbar
talk
02:15, 30 December 2016 (UTC)

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