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Tangeretin

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The low solubility of Tangeretin is one of the main reasons for the low bioavailability of Tangeretin (and other flavonoids in general), and has been reported as a major challenge when using the compound in laboratory procedures. However, methods for tangeretin extraction are currently being tested
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Mizuno, H.; Yoshikawa, H.; Usuki, T. Extraction of Nobiletin and Tangeretin From Peels of Shekwasha and Ponkan Using and Centrifugation. Natural Product Communications 2019, 14, 1-6.
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Tangeretin is commercially available as a dietary supplement. Tangeretin has also demonstrated beneficial applications in other pharmaceutical, nutraceutical, and cosmetic processes.
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to maximize efficiency and percent yields as its uses in treatment of cancer and other diseases are becoming better understood.
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peels. Tangeretin strengthens the cell wall and acts as a plant's defensive mechanism against disease-causing pathogens.
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Panche, A. N.; Diwan, A. D.; Chandra, S. R. Flavonoids: an overview. Journal of Nutritional Science. 2016, 5, 47.
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InChI=1S/C20H20O7/c1-22-12-8-6-11(7-9-12)14-10-13(21)15-16(23-2)18(24-3)20(26-5)19(25-4)17(15)27-14/h6-10H,1-5H3
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InChI=1/C20H20O7/c1-22-12-8-6-11(7-9-12)14-10-13(21)15-16(23-2)18(24-3)20(26-5)19(25-4)17(15)27-14/h6-10H,1-5H3
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565.3 ± 50.0 °C (1,049.5 ± 90.0 °F; 838.4 ± 50.0 K)
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Tangeretin can be found as various synonyms throughout literature and research, including
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It has also been used as a marker compound to detect contamination in citrus juices.
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The following is a list of methods used to extract tangeretin from citrus peels:
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isolation using ionic liquids and a cycle of centrifugation and decantation
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Except where otherwise noted, data are given for materials in their
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a combination of vacuum flash silica gel chromatography and flash C
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SciFinder.com (accessed Nov. 6, 2012). Tangeretin (481-53-8).
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155 to 156 °C (311 to 313 °F; 428 to 429 K)
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O=C2C1=C(OC)C(OC)=C(OC)C(OC)=C1OC(C3=CC=C(OC)C=C3)=C2
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Technol. 2011. 560: 558: 556: 970: 651: 631: 617: 609: 285: 172: 150: 60:5,6,7,8-Tetramethoxy-2-(4-methoxyphenyl)-4 15: 511:high speed counter current chromatography 252: 574: 572: 570: 552: 341: 306: 281: 163: 541:5,6,7,8,4’-pentamethoxyflavone (VIII) 313:Key: ULSUXBXHSYSGDT-UHFFFAOYSA-N 130: 7: 508:super critical fluid chromatography 323:Key: ULSUXBXHSYSGDT-UHFFFAOYAG 223: 207: 14: 443: 31: 22: 842:4',7-Dihydroxy-6-methoxyflavone 439:(at 25 °C , 100 kPa). 49:4′,5,6,7,8-Pentamethoxyflavone 1: 1229:Flavonoids found in Rutaceae 1250: 387:372.37 g/mol 1234:4-Methoxyphenyl compounds 433: 352: 332: 297: 70: 54: 44: 39: 30: 21: 1094:Luteolin-7-O-glucuronide 1058:Hypolaetin 8-glucuronide 734:6,7,4'-Trihydroxyflavone 729:7,8,3'-Trihydroxyflavone 482:polymethoxylated flavone 17:Tangeretin (Tangeritin) 1053:Hypolaetin 8-glucoside 1224:O-methylated flavones 835:O-methylated flavones 688:4',7-Dihydroxyflavone 518:column chromatography 502:column chromatography 56:Systematic IUPAC name 784:Pentahydroxyflavones 743:Tetrahydroxyflavones 693:7,8-Dihydroxyflavone 642:and their conjugates 521:flash chromatography 1154:Sulfated glycosides 424:Solubility in water 64:-1-benzopyran-4-one 18: 1146:Artoindonesianin P 702:Trihydroxyflavones 655:Monohydroxyflavone 466:Infobox references 397:1.244 ± 0.06 g/cm 16: 1211: 1210: 1102: 1101: 960: 959: 811:6-Hydroxyluteolin 676:Dihydroxyflavones 484:that is found in 474:Chemical compound 472: 471: 266:CompTox Dashboard 112:Interactive image 1241: 1089:Veronicastroside 971: 667:6-Hydroxyflavone 662:3-Hydroxyflavone 652: 633: 626: 619: 610: 603: 600: 591: 588: 579: 576: 565: 562: 456: 450: 447: 446: 360:Chemical formula 290: 289: 274: 272: 256: 236: 225: 211: 184: 176: 165: 154: 134: 114: 90: 35: 26: 19: 1249: 1248: 1244: 1243: 1242: 1240: 1239: 1238: 1214: 1213: 1212: 1207: 1186: 1165: 1149: 1130: 1098: 1062: 1041: 1020: 956: 830: 779: 770:Norartocarpetin 760:Isoscutellarein 738: 697: 671: 643: 637: 607: 606: 601: 594: 589: 582: 577: 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25: 20: 1182:Ochnaflavone 1025:of baicalein 931: 877:Cirsimaritin 857:Artocarpetin 775:Scutellarein 540: 536: 534: 531: 527: 497: 494: 477: 476: 71:Identifiers 61: 1126:Scutellarin 1107:Giraldiin A 1079:Isoorientin 1067:of luteolin 1006:Schaftoside 974:of apigenin 867:Cirsilineol 862:Chrysoeriol 353:Properties 170:100.006.883 1218:Categories 1135:Acetylated 1074:Cynaroside 991:Isovitexin 966:Glycosides 932:Tangeretin 927:Sinensetin 922:Salvigenin 912:Oroxylin A 897:Hispidulin 821:Hypolaetin 816:Norwightin 791:Herbacetin 755:Kaempferol 724:Norwogonin 547:References 537:Tangeritin 488:and other 478:Tangeretin 429:0.037 g/L 383:Molar mass 254:I4TLA1DLX6 143:ChemSpider 132:CHEBI:9400 99:3D model ( 78:CAS Number 46:IUPAC name 1203:Hidrosmin 1121:Oroxindin 1011:Vicenin-2 1001:Saponarin 996:Rhoifolin 986:Apigetrin 907:Nobiletin 892:Genkwanin 887:Eupatilin 882:Diosmetin 872:Cirsiliol 801:Quercetin 714:Baicalein 648:Aglycones 486:tangerine 191:207-570-1 183:EC Number 1170:Polymers 1116:Nepitrin 1084:Orientin 1032:Baicalin 847:Acacetin 826:Tricetin 765:Luteolin 719:Galangin 709:Apigenin 640:Flavones 480:is an O- 88:481-53-8 1198:Diosmin 1016:Vitexin 952:Zapotin 947:Wogonin 902:Nepetin 852:Alnetin 750:Fisetin 683:Chrysin 459:what is 457: ( 393:Density 377: 221:PubChem 1037:Tetuin 942:Tricin 917:Pratol 490:citrus 454:verify 451:  337:SMILES 209:C10190 40:Names 1191:Drugs 981:Apiin 796:Morin 302:InChI 234:68077 152:61389 123:ChEBI 101:JSmol 1161:and 1109:and 539:and 245:UNII 200:KEGG 271:EPA 224:CID 1220:: 1163:II 595:^ 583:^ 569:^ 555:^ 543:. 371:20 367:20 1111:B 632:e 625:t 618:v 516:8 449:N 375:7 373:O 369:H 365:C 273:) 269:( 103:) 62:H

Index

Skeletal formula
Ball-and-stick model
IUPAC name
Systematic IUPAC name
CAS Number
481-53-8
JSmol
Interactive image
ChEBI
CHEBI:9400
ChemSpider
61389
ECHA InfoCard
100.006.883
Edit this at Wikidata
EC Number
KEGG
C10190
PubChem
68077
UNII
I4TLA1DLX6
CompTox Dashboard
DTXSID30197417
Edit this at Wikidata
InChI
SMILES
Chemical formula
Molar mass
Density

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