Knowledge (XXG)

Tectin (drug)

Source 📝

168: 56:
Tectin holds promise to relieve severe pain when other standard pain relievers are found to be ineffective. It is also being researched as a drug to relieve the symptoms of withdrawal in
71:
related pain. However interim results from the phase IIb/III clinical trial where the drug did not meet the primary efficacy goal has led to the termination of this trial.
209: 233: 102:"An open-label, multi-dose efficacy and safety study of intramuscular tetrodotoxin in patients with severe cancer-related pain" 202: 27: 80: 43: 195: 60: 228: 100:
Hagen NA, Fisher KM, Lapointe B, du Souich P, Chary S, Moulin D, Sellers E, Ngoc AH (August 2007).
175: 123: 23: 179: 113: 64: 118: 101: 222: 50: 35: 167: 47: 39: 31: 141: 127: 68: 57: 63:. The drug showed promising results in Canadian phase IIa 16:
Brand name for a pain killing drug derived from pufferfish
30:
The drug is a purified version of the main toxin in the
183: 42:which shuts down electrical signaling in nerves by 203: 8: 210: 196: 117: 92: 7: 164: 162: 182:. You can help Knowledge (XXG) by 14: 119:10.1016/j.jpainsymman.2006.11.008 166: 1: 26:currently in development by 250: 161: 234:Brand name products stubs 144:. WEX Pharmaceuticals Inc 44:blocking sodium channels 28:WEX Pharmaceuticals Inc. 22:is the brand name of a 81:Sodium channel blocker 106:J Pain Symptom Manage 67:for the treatment of 191: 190: 24:pain killing drug 241: 212: 205: 198: 170: 163: 153: 152: 150: 149: 138: 132: 131: 121: 97: 38:, a very potent 249: 248: 244: 243: 242: 240: 239: 238: 219: 218: 217: 216: 159: 157: 156: 147: 145: 140: 139: 135: 99: 98: 94: 89: 77: 65:clinical trials 17: 12: 11: 5: 247: 245: 237: 236: 231: 221: 220: 215: 214: 207: 200: 192: 189: 188: 171: 155: 154: 133: 91: 90: 88: 85: 84: 83: 76: 73: 15: 13: 10: 9: 6: 4: 3: 2: 246: 235: 232: 230: 227: 226: 224: 213: 208: 206: 201: 199: 194: 193: 187: 185: 181: 178:article is a 177: 172: 169: 165: 160: 143: 137: 134: 129: 125: 120: 115: 112:(2): 171–82. 111: 107: 103: 96: 93: 86: 82: 79: 78: 74: 72: 70: 66: 62: 59: 54: 52: 49: 45: 41: 37: 33: 29: 25: 21: 184:expanding it 173: 158: 146:. Retrieved 136: 109: 105: 95: 55: 36:tetrodotoxin 19: 18: 229:Analgesics 223:Categories 148:2008-05-02 87:References 48:nerve cell 40:neurotoxin 32:pufferfish 51:membranes 142:"Tectin" 128:17662911 75:See also 176:product 61:addicts 126:  69:cancer 58:opiate 20:Tectin 174:This 180:stub 124:PMID 114:doi 46:on 225:: 122:. 110:34 108:. 104:. 53:. 34:, 211:e 204:t 197:v 186:. 151:. 130:. 116::

Index

pain killing drug
WEX Pharmaceuticals Inc.
pufferfish
tetrodotoxin
neurotoxin
blocking sodium channels
nerve cell
membranes
opiate
addicts
clinical trials
cancer
Sodium channel blocker
"An open-label, multi-dose efficacy and safety study of intramuscular tetrodotoxin in patients with severe cancer-related pain"
doi
10.1016/j.jpainsymman.2006.11.008
PMID
17662911
"Tectin"
Stub icon
product
stub
expanding it
v
t
e
Categories
Analgesics
Brand name products stubs

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.