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Scrub typhus

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293:, but the main limitation of this method is the availability of fluorescent microscopes, which are not often available in resource-poor settings where scrub typhus is endemic. Indirect immunoperoxidase, a modification of the standard IFA method, can be used with a light microscope, and the results of these tests are comparable to those from IFA. Rapid bedside kits have been described that produce a result within one hour, but the availability of these tests is severely limited by their cost. Serological methods are most reliable when a four-fold rise in antibody titre is found. If the patient is from a nonendemic area, then diagnosis can be made from a single acute serum sample. In patients from endemic areas, this is not possible because antibodies may be found in up to 18% of healthy individuals. 402: 53: 278:
often absent since the bite does not inflict pain and the mites are almost too small to be seen by the naked eye. Usually, scrub typhus is often labelled as PUO in remote endemic areas, since blood culture is often negative, yet it can be treated effectively with chloramphenicol. Where doubt exists, the diagnosis may be confirmed by a laboratory test such as
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strains is now recognized, and immunity to one strain does not confer immunity to another. Any scrub typhus vaccine should give protection to all the strains present locally, to give an acceptable level of protection. A vaccine developed for one locality may not be protective in another, because of
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The precise incidence of the disease is unknown, as diagnostic facilities are not available in much of its large native range, which spans vast regions of equatorial jungle to the subtropics. In rural Thailand and Laos, murine and scrub typhus account for around a quarter of all adults presenting to
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in 1942–43, and mentions that to be hospital-evacuated, Allied soldiers (who cycled forces) had to run a fever of 102 Â°F (39 Â°C), and that sickness casualties outnumbered weapons-inflicted casualties 5:1. Similarly, the illness was a casualty producer in all the jungle fighting of the land
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It affects females more than males in Korea, but not in Japan, which may be because sex-differentiated cultural roles have women tending garden plots more often, thus being exposed to vegetation inhabited by chiggers. The incidence is increasing in the southern part of the Indian subcontinent and in
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can be identified, it is quite diagnostic of scrub typhus, but this can be unreliable on dark skin, and moreover, the site of eschar which is usually where the mite bites is often located in covered areas. Unless it is actively searched for, the eschar can easily be missed. History of mite bite is
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in a classified project called "Operation Tyburn"), but the vaccine was not used. The first known batch of scrub typhus vaccine actually used to inoculate human subjects was dispatched to India for use by Allied Land Forces, South-East Asia Command in June 1945. By December 1945, 268,000 cc had
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Suttinont C, Losuwanaluk K, Niwatayakul K, Hoontrakul S, Intaranongpai W, Silpasakorn S, Suwancharoen D, Panlar P, Saisongkorh W (June 2006). "Causes of acute, undifferentiated, febrile illness in rural Thailand: results of a prospective observational study".
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been dispatched. The vaccine was produced at Wellcome's laboratory at Ely Grange, Frant, Sussex. An attempt to verify the efficacy of the vaccine by using a placebo group for comparison was vetoed by the military commanders, who objected to the experiment.
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hospital with fever and negative blood cultures. The incidence in Japan has fallen over the past few decades, probably due to land development driving decreasing exposure, and many prefectures report fewer than 50 cases per year.
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Watt G, Chouriyagune C, Ruangweerayud R, Watcharapichat P, Phulsuksombati D, Jongsakul K, Teja-Isavadharm P, Bhodhidatta D, Corcoran KD (1996). "Scrub typhus infections poorly responsive to antibiotics in northern Thailand".
300:, but these are not routinely available and the results do not always correlate with serological testing, and are affected by prior antibiotic treatment. The currently available diagnostic methods have been summarised. 228:), which are found in areas of heavy scrub vegetation. The mites feed on infected rodent hosts and subsequently transmit the parasite to other rodents and humans. The bite of this mite leaves a characteristic black 493:
Scrub typhus was first reported in Chile in 2006. This is likely the result of underdiagnosis and underreporting and not of a recent spread to Chile. In January 2020 the disease was for the first time reported in
483:. Where the Allies had bases, they could remove and cut back vegetation, or use DDT as a prophylaxis area barrier treatment, so mite- and tick-induced sickness rates in forces off the front lines were diminished. 2608: 261:
In endemic areas, diagnosis is generally made on clinical grounds alone. However, overshadowing of the diagnosis is quite often as the clinical symptoms overlap with other infectious diseases such as
454:, although war records frequently lack definitive diagnoses, and many records of "high fever" evacuations were also likely to be other tropical illnesses. In the chapter entitled "The Green War", 1959:
Watt G, Kantipong P, Jongsakul K, Watcharapichat P, Phulsuksombati D, Strickman D (2000). "Doxycycline and rifampicin for mild scrub-typhus infections in northern Thailand: a randomised trial".
4160: 282:. Again, this is often unavailable in most endemic areas, since the serological test involved is not included in the routine screening tests for PUO, especially in Burma (Myanmar). 4430: 2601: 1086:
Pradutkanchana J, Silpapojakul K, Paxton H, Pradutkanchana S, Kelly DJ, Strickman D (1997). "Comparative evaluation of four serodiagnostic tests for scrub typhus in Thailand".
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The choice of laboratory test is not straightforward, and all currently available tests have their limitations. The cheapest and most easily available serological test is the
507: 5181: 2594: 4153: 1250:"Scrub typhus serologic testing with the indirect immunofluorescence method as a diagnostic gold standard: a lack of consensus leads to a lot of confusion" 1213:
Kelly DJ, Wong PW, Gan E, Lewis GE Jr (1988). "Comparative evaluation of the indirect immunoperoxidase test for the serodiagnosis of rickettsial disease".
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The disease was also a problem for US troops stationed in Japan after WWII, and was variously known as "Shichitƍ fever" (by troops stationed in the
4250: 4146: 393:, died after accidentally pricking her finger with a needle containing scrub typhus while inoculating a mouse in an attempt to develop a vaccine. 655:(Rickettsiales: Rickettsiaceae) in unengorged chiggers (Acari: Trombiculidae) from Oita Prefecture, Japan, by nested polymerase chain reaction". 331:
are alternatives. Azithromycin is an alternative in children and pregnant women with scrub typhus, and when doxycycline resistance is suspected.
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Phongmany S, Rolain JM, Phetsouvanh R, Blacksell SD, Soukkhaseum V, Rasachack B, Phiasakha K, Soukkhaseum S, Frichithavong K (February 2006).
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Mathai E, Rolain JM, Verghese L, Mathai M, Jasper P, Verghese G, Raoult D (2003). "Case reports: scrub typhus during pregnancy in India".
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Sonthayanon P, Chierakul W, Wuthiekanun V, Blacksell SD, Pimda K, Suputtamongkol Y, Pukrittayakamee S, White NJ, Day NP (December 2006).
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Without treatment, the disease is often fatal. Since the use of antibiotics, case fatalities have decreased from 4–40% to less than 2%.
2162:"Antigenic relationship among the eight prototype and new serotype strains of Orientia tsutsugamushi revealed by monoclonal antibodies" 2060: 2003: 1675:
Phimda K, Hoontrakul S, Suttinont C, Chareonwat S, Losuwanaluk K, Chueasuwanchai S, Chierakul W, Suwancharoen D, Silpasakorn S (2007).
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orderly Raphael Oimbari, near Buna on 25 December 1942. Whittington died in February 1943 from the effects of bush typhus. (Picture by
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Kelly DJ, Fuerst PA, Ching WM, Richards AL (2009). "Scrub typhus: The geographic distribution of phenotypic and genotypic variants of
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into northern Australia in the south, and to Pakistan and Afghanistan in the west. It may also be endemic in parts of South America.
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Tseng BY, Yang HH, Liou JH, Chen LK, Hsu YH (February 2008). "Immunohistochemical study of scrub typhus: a report of two cases".
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Tay ST, Nazma S, Rohani MY (1996). "Diagnosis of scrub typhus in Malaysian aborigines using nested polymerase chain reaction".
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is an alternative. Strains that are resistant to doxycycline and chloramphenicol have been reported in northern Thailand.
4802: 4722: 4668: 2808: 5191: 5110: 4638: 4479: 4263: 3978: 3302: 2738: 1769:"Azithromycin Activities against Orientia tsutsugamushi Strains Isolated in Cases of Scrub Typhus in Northern Thailand" 5130: 4751: 4663: 3639: 3633: 3249: 290: 207: 5150: 4952: 3718: 987: 944: 901: 4678: 2696: 4454: 3439: 3274: 3243: 3173: 2954: 988:"Comparative research on epidemiological aspects of tsutsugamushi disease (scrub typhus) between Korea and Japan" 297: 270: 175: 787: 4947: 4653: 4620: 4330: 4245: 4196: 3914: 3696: 3434: 3429: 3313: 3102: 2921: 2844: 2836: 2586: 2531: 316: 224: 163: 3817: 2350:
War epidemics: an historical geography of infectious diseases in military conflict and civil strife, 1850–2000
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Mahajan SK, Rolain JM, Sankhyan N, Kaushal RK, Raoult D (2008). "Pediatric scrub typhus in Indian Himalayas".
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Bozeman FM & Elisberg BL (1963). "Serological diagnosis of scrub typhus by indirect immunofluorescence".
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GonzĂĄlez C (January 29, 2020). "Una bacteria presente en ĂĄcaros causa un raro tipo de infecciĂłn en el sur".
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Ogawa M, Hagiwara T, Kishimoto T, Shiga S, Yoshida Y, Furuya Y, Kaiho I, Ito T, Nemoto H (1 August 2002).
436: 237: 98: 94: 61: 5105: 5083: 4996: 4309: 3951: 3940: 3738: 3368: 3194: 3165: 2972: 2732: 2686: 467: 241:). This extends from northern Japan and far-eastern Russia in the north, to the territories around the 1400:"Usefulness of nested PCR for the diagnosis of scrub typhus in clinical practice: A prospective study" 5140: 4809: 4798: 4425: 4415: 4215: 4112: 4072: 4025: 3907: 3558: 3516: 3496: 3453: 3309: 3108: 2788: 480: 343:. Combination therapy with doxycycline and rifampicin is not recommended due to possible antagonism. 340: 106: 470:
over extremely harsh terrains under intense hardships— fought during a six-month span all along the
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identifies that the disease was one of a number of debilitating afflictions affecting both sides on
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occur in the late phase of illness. It has particularly been shown to be the most common cause of
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World War II provides some indicators that the disease is endemic to undeveloped areas in all of
1166:"Serodiagnosis of tsutsugamushi fever (scrub typhus) by the indirect immunoperoxidase technique" 383:
antigenic variation. This complexity continues to hamper efforts to produce a viable vaccine.
5186: 5098: 4778: 4489: 4063: 4029: 3893: 3825: 3588: 3566: 3535: 2986: 2752: 2542: 2442: 2390: 2386: 2353: 2328: 2303: 2278: 2230: 2183: 2142: 2111: 2011: 1976: 1941: 1883: 1839: 1798: 1741: 1706: 1657: 1639: 1600: 1547: 1511: 1462: 1421: 1380: 1345: 1310: 1271: 1230: 1195: 1138: 1103: 1063: 1007: 964: 921: 874: 838: 770: 729: 672: 633: 559: 495: 455: 69: 2021: 1862:"Scrub typhus during pregnancy and its treatment: a case series and review of the literature" 5135: 5056: 4870: 4838: 4054: 3969: 3760: 3607: 3594: 3409: 3026: 3008: 2915: 2874: 2802: 2672: 2432: 2222: 2173: 2101: 2093: 1968: 1933: 1873: 1829: 1788: 1780: 1733: 1696: 1688: 1647: 1631: 1590: 1539: 1501: 1493: 1452: 1411: 1337: 1302: 1261: 1222: 1185: 1177: 1130: 1095: 1053: 1045: 999: 956: 913: 866: 828: 820: 760: 719: 711: 664: 623: 613: 551: 110: 5176: 5029: 4917: 4741: 4673: 4580: 4400: 4279: 4004: 3925: 3879: 3784: 3724: 3659: 3601: 3570: 3562: 3265: 3235: 3229: 3112: 2941: 2692: 2380: 794: 411: 320: 286: 235:
Scrub typhus is endemic to a part of the world known as the tsutsugamushi triangle (after
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and abnormal liver function tests are commonly seen in the early phase of the illness.
113: 52: 2525: 1972: 1937: 1543: 1190: 1165: 1099: 945:"Annual incidence of tsutsugamushi disease in Miyazaki prefecture, Japan in 2001-2005" 765: 748: 555: 5170: 5115: 4932: 4828: 4784: 4469: 4268: 4226: 4100: 4016: 3843: 3798: 3539: 3531: 3374: 3141: 3052: 2712: 2678: 2653: 2638: 2421:"Scrub typhus in Japan: Epidemiology and clinical features of cases reported in 1998" 1793: 1768: 1753: 1341: 571: 332: 103: 2195: 1988: 1559: 1398:
Kim DM, Yun NR, Yang TY, Lee JH, Yang JT, Shim SK, Choi EN, Park MY, Lee SH (2006).
1357: 1181: 1150: 886: 5120: 5046: 4942: 4714: 4605: 4390: 4304: 4096: 3870: 3349: 3077: 3017: 2964: 2949: 2571: 1635: 1441:"Rapid diagnosis of scrub typhus in rural Thailand using polymerase chain reaction" 684: 471: 432: 328: 262: 219: 199: 183: 171: 17: 2327:. Cave Junction, Oregon: Oregon Institute of Science & Medicine. p. 309. 1677:"Doxycycline versus Azithromycin for Treatment of Leptospirosis and Scrub Typhus" 618: 5125: 4833: 4727: 4693: 4683: 4515: 4325: 4295: 3670: 3625: 3576: 3280: 3032: 2536: 2467: 1482:"Effects of Antibiotic Treatment on the Results of Nested PCRs for Scrub Typhus" 1003: 960: 917: 487: 416: 312: 266: 242: 203: 195: 2574: 2547: 1457: 1440: 1134: 1049: 668: 5013: 5008: 4336: 4286: 4259: 3044: 2510: 2437: 1878: 1861: 1737: 1595: 1574: 1573:
Kollars TM, Bodhidatta D, Phulsuksombati D, Tippayachai B, Coleman RE (2003).
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Watt G, Kantipong P, Jongsakul K, Watcharapichat P, Phulsuksombati D (1999).
1643: 870: 142:. The disease is thus frequently classified separately from the other typhi. 5003: 4848: 4772: 4718: 4186: 3858: 3710: 3378: 3319: 3200: 2566: 1289:
Eamsila C, Singsawat P, Duangvaraporn A, Strickman D (1996). "Antibodies to
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Manchester, p. Six months to recapture Buna and Gona from July 21–22, 1942
2146: 1843: 1551: 1384: 1314: 1234: 1199: 1107: 902:"Scrub typhus (tsutsugamushi disease) in Kanagawa Prefecture in 2001–2005" 715: 5088: 5039: 4902: 4897: 4746: 4235: 4210: 4138: 3294: 1692: 1497: 324: 279: 155: 138: 124: 2493: 1015: 972: 929: 443:; and before 1944, no effective antibiotics or vaccines were available. 5068: 4979: 4907: 4823: 4410: 3885: 3831: 3185: 3150: 2065: 1901:<Please add first missing authors to populate metadata.> (2003). 447: 355: 405:
An Australian soldier, Private George "Dick" Whittington, is aided by
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Jain P, Prakash S, Tripathi PK, Chauhan A, Gupta S, Sharma U (2018).
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Watt G, Parola P (2003). "Scrub typhus and tropical rickettsioses".
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Scrub typhus is transmitted by some species of trombiculid mites ("
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Koh GC, Maude RJ, Paris DH, Newton PN, Blacksell SD (March 2010).
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Katayama T, Hara M, Furuya Y, Nikkawa T, Ogasawara H (June 2006).
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Although the disease is similar in presentation to other forms of
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Blacksell SD, Bryant NJ, Paris, DH, Sakoda Y, Day NP (2007).
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Pham XD, Otsuka Y, Suzuki H, Takaoka H (2001). "Detection of
435:. Several members of the U.S. Army's 5307th Composite Unit ( 943:
Yamamoto S, Ganmyo H, Iwakiri A, Suzuki S (December 2006).
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Kim YS, Lee HJ, Chang M, Son SK, Rhee YE, Shim SK (2006).
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cannot be used safely in pregnancy and is associated with
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Severe epidemics of the disease occurred among troops in
2043:"AWIC Newsletter: The Cotton Rat In Biomedical Research" 1818:"Azithromycin therapy for scrub typhus during pregnancy" 289:, but this is notoriously unreliable. The best test is 788:
Deadly scrub typhus bacteria confirmed in South America
439:) died of the disease, as well as many soldiers in the 232:
that is useful to the doctor for making the diagnosis.
2302:. Barnsley, South Yorkshire: Leo Cooper. p. 212. 1618:
El Sayed I, Liu Q, Wee I, Hine P (24 September 2018).
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Shirai A, Tanskul PL, Andre, RG, Huxsoll DL (1981). "
2008:
CDC Health Information for International Travel, 2008
2483: 2352:. Oxford: Oxford University Press. pp. 489–91. 4970: 4890: 4869: 4760: 4707: 4568: 4559: 4550: 4503: 4359: 4350: 4318: 4293: 4277: 4224: 4194: 4185: 4176: 4062: 4053: 4015: 3988: 3968: 3924: 3869: 3842: 3797: 3771: 3735: 3667: 3658: 3550: 3515: 3506: 3463: 3358: 3343: 3334: 3264: 3211: 3184: 3149: 3140: 3131: 3043: 3016: 3007: 2940: 2905: 2864: 2722: 2711: 2662: 2646: 2637: 2628: 2557: 2487: 809:"Rickettsial infections and fever, Vientiane, Laos" 68: 42: 37: 2133:strains found in chiggers collected in Thailand". 1081: 1079: 1077: 704:American Journal of Tropical Medicine and Hygiene 508:List of mites associated with cutaneous reactions 116:first isolated and identified in 1930 in Japan. 2460: 2458: 2456: 2277:. London: University of London, Athlone Press. 1907:Abstr Intersci Conf Antimicrob Agents Chemother 4154: 2602: 8: 1624:The Cochrane Database of Systematic Reviews 5146:Recurrent toxin-mediated perineal erythema 4565: 4556: 4432:Mycobacterium avium–intracellulare complex 4356: 4191: 4182: 4161: 4147: 4139: 4059: 3664: 3512: 3355: 3340: 3146: 3137: 3013: 2719: 2659: 2643: 2634: 2609: 2595: 2587: 2484: 2371: 2369: 1855: 1853: 1027: 1025: 747:Seong SY, Choi MS, Kim IS (January 2001). 583: 581: 354:An early attempt to create a scrub typhus 51: 34: 4241:Cutaneous group B streptococcal infection 2436: 2177: 2105: 1877: 1833: 1792: 1700: 1651: 1594: 1505: 1456: 1415: 1265: 1189: 1057: 832: 764: 723: 627: 617: 490:) or "Hatsuka fever" (Chiba prefecture). 2135:Southeast Asian J Trop Med Public Health 1373:Southeast Asian J Trop Med Public Health 136:with the typhus bacteria proper, but in 2002:Arguin PM, Kozarsky PE, Reed C (2008). 1620:"Antibiotics for treating scrub typhus" 1164:Yamamoto S & Minamishima Y (1982). 519: 46:Bush typhus, mite typhus, jungle typhus 5182:Bacterium-related cutaneous conditions 4465:Rapid growing mycobacterium infection 3775:Aggregatibacter actinomycetemcomitans 700:"Evolution of Eschar in Scrub Typhus" 7: 4644:Human granulocytotropic anaplasmosis 4206:Staphylococcal scalded skin syndrome 3160:Neisseria meningitidis/meningococcus 2348:Smallman-Raynor M, Cliff AD (2004). 351:No licensed vaccines are available. 5094:Chronic undermining burrowing ulcer 2004:"Chapter 4: Rickettsial Infections" 1579:isolated from patients in Thailand" 2622:Gram-negative bacterial infections 2179:10.1111/j.1348-0421.1999.tb02397.x 296:Other methods include culture and 253:northern areas around Darjeeling. 27:Disease caused by O. tsutsugamushi 25: 5052:Superficial pustular folliculitis 4649:Human monocytotropic ehrlichiosis 2979:Human monocytotropic ehrlichiosis 2385:. Little Brown Company. pp.  2069:. Millbanksystems. April 2, 1946. 4460:Primary inoculation tuberculosis 3195:Neisseria gonorrhoeae/gonococcus 3170:Waterhouse–Friderichsen syndrome 2061:"Scrub Typhus Vaccine, Far East" 1342:10.1097/00001432-200310000-00009 986:Bang HA, Lee MJ, Lee WC (2008). 4958:Gram-negative toe web infection 4534:Group JK corynebacterium sepsis 2961:Human granulocytic anaplasmosis 2066:Parliamentary Debates (Hansard) 1182:10.1128/JCM.15.6.1128-1132.1982 531:. London: Sassell. p. 177. 311:The drug most commonly used is 4699:Ehrlichiosis ewingii infection 4521:Cutaneous diphtheria infection 4475:Tuberculosis cutis orificialis 4386:Borderline tuberculoid leprosy 4376:Borderline lepromatous leprosy 2993:Ehrlichiosis ewingii infection 1636:10.1002/14651858.CD002150.pub2 797:. ScienMag (September 8, 2016) 1: 4723:Primary gonococcal dermatitis 4669:Flinders Island spotted fever 2809:Flinders Island spotted fever 1973:10.1016/S0140-6736(00)02728-8 1938:10.1016/S0035-9203(03)80032-9 1544:10.1016/S0140-6736(96)02501-9 1100:10.1016/S0035-9203(97)90266-2 766:10.1016/S1286-4579(00)01352-6 590:, accessdate: 16 October 2011 556:10.1016/S1607-551X(08)70103-7 5111:Blistering distal dactylitis 4639:Rocky Mountain spotted fever 4527:Arcanobacterium haemolyticum 4480:Tuberculosis verrucosa cutis 4264:Chronic recurrent erysipelas 3979:Stenotrophomonas maltophilia 3303:Burkholderia cepacia complex 2739:Rocky Mountain spotted fever 2325:Jungle Snafus...And Remedies 2215:Clinical Infectious Diseases 1726:Indian Journal of Pediatrics 619:10.1371/journal.pntd.0006346 5131:Blastomycosis-like pyoderma 4752:Chromobacteriosis infection 4664:Mediterranean spotted fever 3640:Far East scarlet-like fever 3634:Yersinia pseudotuberculosis 3250:Chromobacteriosis infection 1773:Antimicrob Agents Chemother 1681:Antimicrob Agents Chemother 1034:"Diagnosis of scrub typhus" 1004:10.7883/yoken.JJID.2008.148 961:10.7883/yoken.JJID.2006.404 918:10.7883/yoken.JJID.2006.207 496:Chile's southernmost region 291:indirect immunofluorescence 208:acute encephalitis syndrome 166:. More virulent strains of 150:Signs and symptoms include 5208: 5151:Tick-borne lymphadenopathy 4953:Gram-negative folliculitis 2298:Grant, Ian Lyall- (2003). 2160:Kang JS, Chang WH (1999). 1458:10.4269/ajtmh.2006.75.1099 1135:10.3181/00379727-112-28107 1050:10.4269/ajtmh.2010.09-0233 669:10.1603/0022-2585-38.2.308 4455:Papulonecrotic tuberculid 4440:Mycobacterium haemophilum 3440:Hemolytic-uremic syndrome 3275:Burkholderia pseudomallei 3244:Chromobacterium violaceum 3174:Meningococcal septicaemia 2955:Anaplasma phagocytophilum 2471:(in Spanish). p. A9. 2438:10.4269/ajtmh.2002.67.162 2379:(1978). "The Green War". 2080:Thomson Walker W (1947). 1879:10.4269/ajtmh.2006.75.955 1738:10.1007/s12098-008-0198-z 1596:10.4269/ajtmh.2003.68.299 1417:10.4269/ajtmh.2006.75.542 1307:10.4269/ajtmh.1996.55.556 1227:10.4269/ajtmh.1988.38.400 366:infecting around 300,000 298:polymerase chain reaction 271:pyrexia of unknown origin 176:intravascular coagulation 164:gastrointestinal symptoms 127:is no longer included in 59: 50: 4948:Lymphogranuloma venereum 4654:Flea-borne spotted fever 4627:Rickettsia aeschlimannii 4621:American tick bite fever 4331:Erysipeloid of Rosenbach 4246:Streptococcal intertrigo 3915:Plesiomonas shigelloides 3697:Brazilian purpuric fever 3314:Bordetella parapertussis 3103:Bartonella bacilliformis 2922:Flea-borne spotted fever 2852:Rickettsia aeschlimannii 2845:Rickettsia aeschlimannii 2837:American tick bite fever 2300:Burma: The Turning Point 2249:"Death from Scrub Fever" 2131:Rickettsia tsutsugamushi 1926:Trans R Soc Trop Med Hyg 1480:Kim DM, Byun JN (2008). 1088:Trans R Soc Trop Med Hyg 871:10.1179/136485906X112158 225:Leptotrombidium deliense 5079:Trichomycosis axillaris 4616:African tick bite fever 4591:North Asian tick typhus 4511:Cutaneous actinomycosis 4083:Guillain–BarrĂ© syndrome 3999:Cardiobacterium hominis 3959:Acinetobacter baumannii 3901:Vibrio parahaemolyticus 3620:Yersinia enterocolitica 3387:Klebsiella granulomatis 2823:African tick bite fever 2781:North Asian tick typhus 1816:Choi EK, Pai H (1998). 4791:Haemophilus influenzae 4735:Pasteurella hemolytica 4659:Japanese spotted fever 4611:Bacillary angiomatosis 4601:Flying squirrel typhus 4596:Queensland tick typhus 4485:Tuberculous cellulitis 4448:Mycobacterium kansasii 4170:Bacterial skin disease 3935:Pseudomonas aeruginosa 3853:Francisella tularensis 3812:Legionella longbeachae 3808:Legionella pneumophila 3450:Enterobacter aerogenes 3095:Bacillary angiomatosis 2889:Orientia tsutsugamushi 2795:Queensland tick typhus 2767:Japanese spotted fever 2701:Flying squirrel typhus 2211:Orientia tsutsugamushi 2098:10.1136/bmj.1.4501.484 2082:"Scrub Typhus Vaccine" 1785:10.1128/AAC.43.11.2817 1577:Orientia tsutsugamushi 1291:Orientia tsutsugamushi 859:Ann Trop Med Parasitol 825:10.3201/eid1202.050900 653:Orientia tsutsugamushi 588:Pediatric Scrub Typhus 527:Slim, William (1956). 466:in the running bloody 420: 380:Orientia tsutsugamushi 99:Orientia tsutsugamushi 95:intracellular parasite 62:Orientia tsutsugamushi 5106:Elephantiasis nostras 5084:Necrotizing fasciitis 4997:Hospital furunculosis 4679:Brill–Zinsser disease 4310:Dermatitis gangrenosa 3952:Moraxella catarrhalis 3818:Legionnaires' disease 3739:Pasteurella multocida 3369:Klebsiella pneumoniae 3166:Meningococcal disease 2973:Ehrlichia chaffeensis 2733:Rickettsia rickettsii 2697:Brill–Zinsser disease 2687:Rickettsia prowazekii 1913:: abstract no. L–182. 1445:Am. J. Trop. Med. Hyg 1123:Proc Soc Exp Biol Med 1038:Am. J. Trop. Med. Hyg 716:10.4269/ajtmh.16-0583 544:Kaohsiung J. Med. Sci 404: 178:. Morbilliform rash, 5141:Chronic lymphangitis 4810:Hot tub folliculitis 4799:Pseudomonal pyoderma 4426:Miliary tuberculosis 4416:Lichen scrofulosorum 4216:Toxic shock syndrome 4113:Helicobacter cinaedi 4073:Campylobacter jejuni 4026:Aeromonas hydrophila 3908:Vibrio alginolyticus 3559:Shigella dysenteriae 3497:Citrobacter freundii 3454:Enterobacter cloacae 3310:Bordetella pertussis 2789:Rickettsia australis 2275:Red mites and typhus 1693:10.1128/AAC.00508-07 1498:10.1128/JCM.00634-08 1330:Curr Opin Infect Dis 813:Emerging Infect. Dis 481:Guadalcanal campaign 5192:Tick-borne diseases 5030:Acute lymphadenitis 5023:Perianal cellulitis 5018:Pyogenic paronychia 4928:Chlamydia infection 4844:Granuloma inguinale 4818:Green nail syndrome 4814:Ecthyma gangrenosum 4689:Cat-scratch disease 4495:Tuberculoid leprosy 4406:Lepromatous leprosy 4253:Streptococcus iniae 4091:Helicobacter pylori 3581:Bacillary dysentery 3526:Salmonella enterica 3474:Serratia marcescens 3393:Granuloma inguinale 3289:Burkholderia mallei 3224:Eikenella corrodens 3072:Bartonella quintana 3064:Cat-scratch disease 3058:Bartonella henselae 2775:Rickettsia sibirica 2761:Rickettsia japonica 1967:(9235): 1057–1061. 1293:in Thai soldiers". 529:Defeat Into Victory 477:New Guinea campaign 437:Merrill's Marauders 376:antigenic variation 364:Wellcome Foundation 190:are typical signs. 18:Tsutsugamushi fever 5074:Pitted keratolysis 4985:Periapical abscess 4396:Erythema induratum 4381:Borderline leprosy 4371:Aquarium granuloma 4079:Campylobacteriosis 3990:Cardiobacteriaceae 3491:Citrobacter koseri 3401:Klebsiella oxytoca 2831:Rickettsia parkeri 2817:Rickettsia africae 2747:Rickettsia conorii 2558:External resources 2377:William Manchester 2323:Kearny CH (1997). 793:2019-09-23 at the 606:PLOS Negl Trop Dis 460:William Manchester 421: 362:in 1937 (with the 146:Signs and symptoms 75:Infectious disease 5164: 5163: 5099:Fournier gangrene 4966: 4965: 4865: 4864: 4806:hot-foot syndrome 4779:Vibrio vulnificus 4546: 4545: 4542: 4541: 4490:Tuberculous gumma 4346: 4345: 4136: 4135: 4132: 4131: 4064:Campylobacterales 4049: 4048: 4030:Aeromonas veronii 3894:Vibrio vulnificus 3826:Coxiella burnetii 3793: 3792: 3719:H. parainfluenzae 3654: 3653: 3650: 3649: 3589:Proteus mirabilis 3536:Paratyphoid fever 3425:Enterohemorrhagic 3345:Enterobacteriales 3330: 3329: 3260: 3259: 3127: 3126: 3123: 3122: 3109:Carrion's disease 3003: 3002: 2987:Ehrlichia ewingii 2936: 2935: 2932: 2931: 2753:Boutonneuse fever 2584: 2583: 2425:Am J Trop Med Hyg 2396:978-0-316-54498-6 2359:978-0-19-823364-0 2334:978-1-884067-10-5 2284:978-0-485-26318-3 2166:Microbiol Immunol 2017:978-0-323-04885-9 1866:Am J Trop Med Hyg 1779:(11): 2817–2818. 1583:Am J Trop Med Hyg 1404:Am J Trop Med Hyg 1295:Am J Trop Med Hyg 1215:Am J Trop Med Hyg 488:Izu Seven Islands 456:General MacArthur 210:in Bihar, India. 188:lymphadenopathies 107:α-proteobacterium 80: 79: 32:Medical condition 16:(Redirected from 5199: 5136:Bullous impetigo 5057:Sycosis vulgaris 4871:Campylobacterota 4820: 4566: 4557: 4357: 4192: 4183: 4163: 4156: 4149: 4140: 4060: 3970:Xanthomonadaceae 3778: 3761:Actinobacillosis 3742: 3675: 3665: 3595:Proteus vulgaris 3513: 3410:Escherichia coli 3356: 3341: 3216: 3147: 3138: 3027:Brucella abortus 3014: 3009:Hyphomicrobiales 2916:Rickettsia felis 2875:Rickettsia akari 2803:Rickettsia honei 2720: 2673:Rickettsia typhi 2660: 2644: 2635: 2611: 2604: 2597: 2588: 2485: 2473: 2472: 2462: 2451: 2450: 2440: 2416: 2410: 2407: 2401: 2400: 2373: 2364: 2363: 2345: 2339: 2338: 2320: 2314: 2313: 2295: 2289: 2288: 2273:Audy JR (1968). 2270: 2264: 2263: 2261: 2260: 2253:Kalgoorlie Miner 2245: 2239: 2238: 2206: 2200: 2199: 2181: 2157: 2151: 2150: 2126: 2120: 2119: 2109: 2077: 2071: 2070: 2057: 2051: 2050: 2045:. Archived from 2039: 2033: 2032: 2030: 2029: 2020:. Archived from 1999: 1993: 1992: 1956: 1950: 1949: 1921: 1915: 1914: 1898: 1892: 1891: 1881: 1857: 1848: 1847: 1837: 1813: 1807: 1806: 1796: 1764: 1758: 1757: 1721: 1715: 1714: 1704: 1672: 1666: 1665: 1655: 1615: 1609: 1608: 1598: 1570: 1564: 1563: 1526: 1520: 1519: 1509: 1486:J Clin Microbiol 1477: 1471: 1470: 1460: 1436: 1430: 1429: 1419: 1395: 1389: 1388: 1368: 1362: 1361: 1325: 1319: 1318: 1286: 1280: 1279: 1269: 1245: 1239: 1238: 1210: 1204: 1203: 1193: 1170:J Clin Microbiol 1161: 1155: 1154: 1118: 1112: 1111: 1083: 1072: 1071: 1061: 1029: 1020: 1019: 1014:. Archived from 992:Jpn J Infect Dis 983: 977: 976: 971:. Archived from 949:Jpn J Infect Dis 940: 934: 933: 928:. Archived from 906:Jpn J Infect Dis 897: 891: 890: 853: 847: 846: 836: 804: 798: 785: 779: 778: 768: 744: 738: 737: 727: 710:(6): 1223–1224. 695: 689: 688: 648: 642: 641: 631: 621: 597: 591: 585: 576: 575: 539: 533: 532: 524: 389:, an Australian 358:occurred in the 238:O. tsutsugamushi 222:", particularly 168:O. tsutsugamushi 55: 35: 21: 5207: 5206: 5202: 5201: 5200: 5198: 5197: 5196: 5167: 5166: 5165: 5160: 4972: 4962: 4886: 4861: 4797: 4756: 4742:Meningococcemia 4703: 4674:Verruga peruana 4581:Epidemic typhus 4538: 4499: 4401:Histoid leprosy 4362: 4342: 4314: 4289: 4280:Corynebacterium 4273: 4220: 4172: 4167: 4137: 4128: 4045: 4011: 3984: 3964: 3926:Pseudomonadales 3920: 3880:Vibrio cholerae 3865: 3838: 3789: 3772: 3767: 3736: 3731: 3668: 3646: 3602:Yersinia pestis 3546: 3502: 3459: 3415:Enterotoxigenic 3347: 3326: 3266:Burkholderiales 3256: 3230:Kingella kingae 3212: 3207: 3180: 3119: 3113:Verruga peruana 3039: 2999: 2942:Anaplasmataceae 2928: 2901: 2860: 2714: 2707: 2693:Epidemic typhus 2651: 2624: 2615: 2585: 2580: 2579: 2553: 2552: 2496: 2482: 2477: 2476: 2464: 2463: 2454: 2418: 2417: 2413: 2408: 2404: 2397: 2382:American Caesar 2375: 2374: 2367: 2360: 2347: 2346: 2342: 2335: 2322: 2321: 2317: 2310: 2297: 2296: 2292: 2285: 2272: 2271: 2267: 2258: 2256: 2247: 2246: 2242: 2221:(s3): S203–30. 2208: 2207: 2203: 2159: 2158: 2154: 2128: 2127: 2123: 2092:(4501): 484–7. 2079: 2078: 2074: 2059: 2058: 2054: 2041: 2040: 2036: 2027: 2025: 2018: 2001: 2000: 1996: 1958: 1957: 1953: 1923: 1922: 1918: 1900: 1899: 1895: 1859: 1858: 1851: 1822:Clin Infect Dis 1815: 1814: 1810: 1766: 1765: 1761: 1723: 1722: 1718: 1674: 1673: 1669: 1630:(9): CD002150. 1617: 1616: 1612: 1572: 1571: 1567: 1538:(9020): 86–89. 1528: 1527: 1523: 1479: 1478: 1474: 1451:(6): 1099–102. 1438: 1437: 1433: 1397: 1396: 1392: 1370: 1369: 1365: 1327: 1326: 1322: 1288: 1287: 1283: 1254:Clin Infect Dis 1247: 1246: 1242: 1212: 1211: 1207: 1163: 1162: 1158: 1120: 1119: 1115: 1085: 1084: 1075: 1031: 1030: 1023: 985: 984: 980: 942: 941: 937: 899: 898: 894: 855: 854: 850: 806: 805: 801: 795:Wayback Machine 786: 782: 753:Microbes Infect 746: 745: 741: 698:Park J (2016). 697: 696: 692: 650: 649: 645: 612:(3): e0006346. 599: 598: 594: 586: 579: 541: 540: 536: 526: 525: 521: 516: 504: 475:battles of the 452:Pacific theater 399: 349: 321:chloramphenicol 306: 287:Weil-Felix test 259: 216: 158:, muscle pain, 148: 33: 28: 23: 22: 15: 12: 11: 5: 5205: 5203: 5195: 5194: 5189: 5184: 5179: 5169: 5168: 5162: 5161: 5159: 5158: 5156:Tropical ulcer 5153: 5148: 5143: 5138: 5133: 5128: 5123: 5118: 5113: 5108: 5103: 5102: 5101: 5096: 5086: 5081: 5076: 5071: 5066: 5061: 5060: 5059: 5054: 5043: 5042: 5037: 5035:Pilonidal cyst 5032: 5027: 5026: 5025: 5020: 5006: 5001: 5000: 4999: 4989: 4988: 4987: 4976: 4974: 4968: 4967: 4964: 4963: 4961: 4960: 4955: 4950: 4945: 4940: 4938:Rat-bite fever 4935: 4930: 4925: 4920: 4915: 4910: 4905: 4900: 4894: 4892: 4888: 4887: 4885: 4884: 4875: 4873: 4867: 4866: 4863: 4862: 4860: 4859: 4851: 4846: 4841: 4836: 4831: 4826: 4821: 4795: 4787: 4782: 4775: 4770: 4768:Pasteurellosis 4764: 4762: 4758: 4757: 4755: 4754: 4749: 4744: 4739: 4730: 4725: 4711: 4709: 4705: 4704: 4702: 4701: 4696: 4691: 4686: 4681: 4676: 4671: 4666: 4661: 4656: 4651: 4646: 4641: 4636: 4634:Rickettsialpox 4631: 4623: 4618: 4613: 4608: 4603: 4598: 4593: 4588: 4583: 4578: 4576:Endemic typhus 4572: 4570: 4563: 4561:Pseudomonadota 4554: 4548: 4547: 4544: 4543: 4540: 4539: 4537: 4536: 4531: 4523: 4518: 4513: 4507: 4505: 4501: 4500: 4498: 4497: 4492: 4487: 4482: 4477: 4472: 4467: 4462: 4457: 4452: 4444: 4436: 4428: 4423: 4421:Lupus vulgaris 4418: 4413: 4408: 4403: 4398: 4393: 4388: 4383: 4378: 4373: 4367: 4365: 4361:Mycobacterium- 4354: 4352:Actinomycetota 4348: 4347: 4344: 4343: 4341: 4340: 4333: 4328: 4322: 4320: 4316: 4315: 4313: 4312: 4307: 4301: 4299: 4291: 4290: 4285: 4283: 4275: 4274: 4272: 4271: 4266: 4257: 4248: 4243: 4238: 4232: 4230: 4222: 4221: 4219: 4218: 4213: 4208: 4202: 4200: 4197:Staphylococcus 4189: 4180: 4174: 4173: 4168: 4166: 4165: 4158: 4151: 4143: 4134: 4133: 4130: 4129: 4127: 4126: 4125: 4124: 4109: 4108: 4107: 4105:Gastric cancer 4087: 4086: 4085: 4068: 4066: 4057: 4051: 4050: 4047: 4046: 4044: 4043: 4042: 4041: 4021: 4019: 4013: 4012: 4010: 4009: 4008: 4007: 3994: 3992: 3986: 3985: 3983: 3982: 3974: 3972: 3966: 3965: 3963: 3962: 3955: 3948: 3947: 3946: 3930: 3928: 3922: 3921: 3919: 3918: 3911: 3904: 3897: 3890: 3889: 3888: 3875: 3873: 3867: 3866: 3864: 3863: 3862: 3861: 3848: 3846: 3840: 3839: 3837: 3836: 3835: 3834: 3822: 3821: 3820: 3803: 3801: 3795: 3794: 3791: 3790: 3788: 3787: 3781: 3779: 3769: 3768: 3766: 3765: 3764: 3763: 3755:Actinobacillus 3751: 3749:Pasteurellosis 3745: 3743: 3733: 3732: 3730: 3729: 3728: 3727: 3715: 3714: 3713: 3701: 3700: 3699: 3694: 3678: 3676: 3662: 3660:Pasteurellales 3656: 3655: 3652: 3651: 3648: 3647: 3645: 3644: 3643: 3642: 3630: 3629: 3628: 3616: 3615: 3614: 3612:Bubonic plague 3598: 3585: 3584: 3583: 3554: 3552: 3548: 3547: 3545: 3544: 3543: 3542: 3521: 3519: 3510: 3504: 3503: 3501: 3500: 3487: 3486: 3485: 3469: 3467: 3461: 3460: 3458: 3457: 3445: 3444: 3443: 3442: 3432: 3427: 3422: 3420:Enteroinvasive 3417: 3405: 3404: 3397: 3396: 3395: 3383: 3382: 3381: 3364: 3362: 3353: 3338: 3332: 3331: 3328: 3327: 3325: 3324: 3323: 3322: 3306: 3299: 3298: 3297: 3285: 3284: 3283: 3270: 3268: 3262: 3261: 3258: 3257: 3255: 3254: 3253: 3252: 3240: 3239: 3238: 3219: 3217: 3209: 3208: 3206: 3205: 3204: 3203: 3190: 3188: 3182: 3181: 3179: 3178: 3177: 3176: 3155: 3153: 3144: 3135: 3129: 3128: 3125: 3124: 3121: 3120: 3118: 3117: 3116: 3115: 3099: 3098: 3097: 3082: 3081: 3080: 3068: 3067: 3066: 3049: 3047: 3045:Bartonellaceae 3041: 3040: 3038: 3037: 3036: 3035: 3022: 3020: 3011: 3005: 3004: 3001: 3000: 2998: 2997: 2996: 2995: 2983: 2982: 2981: 2969: 2968: 2967: 2946: 2944: 2938: 2937: 2934: 2933: 2930: 2929: 2927: 2926: 2925: 2924: 2911: 2909: 2903: 2902: 2900: 2899: 2898: 2897: 2885: 2884: 2883: 2881:Rickettsialpox 2870: 2868: 2862: 2861: 2859: 2858: 2857: 2856: 2841: 2840: 2839: 2827: 2826: 2825: 2813: 2812: 2811: 2799: 2798: 2797: 2785: 2784: 2783: 2771: 2770: 2769: 2757: 2756: 2755: 2743: 2742: 2741: 2728: 2726: 2717: 2709: 2708: 2706: 2705: 2704: 2703: 2683: 2682: 2681: 2668: 2666: 2657: 2648:Rickettsiaceae 2641: 2632: 2626: 2625: 2618:Pseudomonadota 2616: 2614: 2613: 2606: 2599: 2591: 2582: 2581: 2578: 2577: 2562: 2561: 2559: 2555: 2554: 2551: 2550: 2539: 2528: 2513: 2497: 2492: 2491: 2489: 2488:Classification 2481: 2480:External links 2478: 2475: 2474: 2452: 2411: 2402: 2395: 2365: 2358: 2340: 2333: 2315: 2308: 2290: 2283: 2265: 2240: 2227:10.1086/596576 2201: 2152: 2121: 2072: 2052: 2049:on 2004-06-10. 2034: 2016: 1994: 1951: 1916: 1893: 1849: 1835:10.1086/517742 1808: 1759: 1716: 1687:(9): 3259–63. 1667: 1610: 1589:(3): 299–300. 1565: 1521: 1472: 1431: 1410:(3): 542–545. 1390: 1363: 1336:(5): 429–436. 1320: 1281: 1267:10.1086/510585 1260:(3): 391–401. 1240: 1205: 1156: 1113: 1073: 1021: 1018:on 2008-09-27. 978: 975:on 2009-08-15. 935: 932:on 2010-05-25. 892: 848: 799: 780: 739: 690: 663:(2): 308–311. 643: 592: 577: 534: 518: 517: 515: 512: 511: 510: 503: 500: 468:Kokoda battles 458:'s biographer 398: 395: 391:bacteriologist 360:United Kingdom 348: 345: 305: 302: 273:(PUO). If the 258: 255: 215: 212: 147: 144: 114:Rickettsiaceae 93:caused by the 78: 77: 72: 66: 65: 57: 56: 48: 47: 44: 40: 39: 31: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 5204: 5193: 5190: 5188: 5185: 5183: 5180: 5178: 5175: 5174: 5172: 5157: 5154: 5152: 5149: 5147: 5144: 5142: 5139: 5137: 5134: 5132: 5129: 5127: 5124: 5122: 5119: 5117: 5116:Botryomycosis 5114: 5112: 5109: 5107: 5104: 5100: 5097: 5095: 5092: 5091: 5090: 5087: 5085: 5082: 5080: 5077: 5075: 5072: 5070: 5067: 5065: 5062: 5058: 5055: 5053: 5050: 5049: 5048: 5045: 5044: 5041: 5038: 5036: 5033: 5031: 5028: 5024: 5021: 5019: 5015: 5012: 5011: 5010: 5007: 5005: 5002: 4998: 4995: 4994: 4993: 4992:Boil/furuncle 4990: 4986: 4983: 4982: 4981: 4978: 4977: 4975: 4969: 4959: 4956: 4954: 4951: 4949: 4946: 4944: 4941: 4939: 4936: 4934: 4933:Leptospirosis 4931: 4929: 4926: 4924: 4921: 4919: 4916: 4914: 4911: 4909: 4906: 4904: 4901: 4899: 4896: 4895: 4893: 4889: 4883: 4881: 4877: 4876: 4874: 4872: 4868: 4858: 4856: 4852: 4850: 4847: 4845: 4842: 4840: 4837: 4835: 4832: 4830: 4829:Salmonellosis 4827: 4825: 4822: 4819: 4815: 4811: 4807: 4805: 4800: 4796: 4794: 4792: 4788: 4786: 4785:Rhinoscleroma 4783: 4781: 4780: 4776: 4774: 4771: 4769: 4766: 4765: 4763: 4759: 4753: 4750: 4748: 4745: 4743: 4740: 4738: 4736: 4731: 4729: 4726: 4724: 4720: 4716: 4713: 4712: 4710: 4706: 4700: 4697: 4695: 4692: 4690: 4687: 4685: 4682: 4680: 4677: 4675: 4672: 4670: 4667: 4665: 4662: 4660: 4657: 4655: 4652: 4650: 4647: 4645: 4642: 4640: 4637: 4635: 4632: 4630: 4628: 4624: 4622: 4619: 4617: 4614: 4612: 4609: 4607: 4604: 4602: 4599: 4597: 4594: 4592: 4589: 4587: 4584: 4582: 4579: 4577: 4574: 4573: 4571: 4567: 4564: 4562: 4558: 4555: 4553: 4549: 4535: 4532: 4530: 4528: 4524: 4522: 4519: 4517: 4514: 4512: 4509: 4508: 4506: 4502: 4496: 4493: 4491: 4488: 4486: 4483: 4481: 4478: 4476: 4473: 4471: 4470:Scrofuloderma 4468: 4466: 4463: 4461: 4458: 4456: 4453: 4451: 4449: 4445: 4443: 4441: 4437: 4435: 4433: 4429: 4427: 4424: 4422: 4419: 4417: 4414: 4412: 4409: 4407: 4404: 4402: 4399: 4397: 4394: 4392: 4389: 4387: 4384: 4382: 4379: 4377: 4374: 4372: 4369: 4368: 4366: 4364: 4358: 4355: 4353: 4349: 4339: 4338: 4334: 4332: 4329: 4327: 4324: 4323: 4321: 4317: 4311: 4308: 4306: 4303: 4302: 4300: 4298: 4297: 4292: 4288: 4284: 4282: 4281: 4276: 4270: 4269:Scarlet fever 4267: 4265: 4261: 4258: 4256: 4254: 4249: 4247: 4244: 4242: 4239: 4237: 4234: 4233: 4231: 4229: 4228: 4227:Streptococcus 4223: 4217: 4214: 4212: 4209: 4207: 4204: 4203: 4201: 4199: 4198: 4193: 4190: 4188: 4184: 4181: 4179: 4175: 4171: 4164: 4159: 4157: 4152: 4150: 4145: 4144: 4141: 4123: 4121: 4117: 4116: 4115: 4114: 4110: 4106: 4102: 4101:MALT lymphoma 4098: 4095: 4094: 4093: 4092: 4088: 4084: 4080: 4077: 4076: 4075: 4074: 4070: 4069: 4067: 4065: 4061: 4058: 4056: 4052: 4040: 4038: 4034: 4033: 4032: 4031: 4027: 4023: 4022: 4020: 4018: 4017:Aeromonadales 4014: 4006: 4003: 4002: 4001: 4000: 3996: 3995: 3993: 3991: 3987: 3981: 3980: 3976: 3975: 3973: 3971: 3967: 3961: 3960: 3956: 3954: 3953: 3949: 3945: 3943: 3939: 3938: 3937: 3936: 3932: 3931: 3929: 3927: 3923: 3917: 3916: 3912: 3910: 3909: 3905: 3903: 3902: 3898: 3896: 3895: 3891: 3887: 3884: 3883: 3882: 3881: 3877: 3876: 3874: 3872: 3868: 3860: 3857: 3856: 3855: 3854: 3850: 3849: 3847: 3845: 3844:Thiotrichales 3841: 3833: 3830: 3829: 3828: 3827: 3823: 3819: 3816: 3815: 3814: 3813: 3809: 3805: 3804: 3802: 3800: 3799:Legionellales 3796: 3786: 3783: 3782: 3780: 3777: 3776: 3770: 3762: 3759: 3758: 3757: 3756: 3752: 3750: 3747: 3746: 3744: 3741: 3740: 3734: 3726: 3723: 3722: 3721: 3720: 3716: 3712: 3709: 3708: 3707: 3706: 3702: 3698: 3695: 3693: 3691: 3687: 3686: 3685: 3684: 3683:H. influenzae 3680: 3679: 3677: 3674: 3672: 3666: 3663: 3661: 3657: 3641: 3638: 3637: 3636: 3635: 3631: 3627: 3624: 3623: 3622: 3621: 3617: 3613: 3609: 3606: 3605: 3604: 3603: 3599: 3597: 3596: 3591: 3590: 3586: 3582: 3578: 3575: 3574: 3573: 3572: 3568: 3564: 3560: 3556: 3555: 3553: 3549: 3541: 3540:Salmonellosis 3537: 3533: 3532:Typhoid fever 3530: 3529: 3528: 3527: 3523: 3522: 3520: 3518: 3514: 3511: 3509: 3505: 3499: 3498: 3493: 3492: 3488: 3484: 3482: 3478: 3477: 3476: 3475: 3471: 3470: 3468: 3466: 3462: 3456: 3455: 3451: 3447: 3446: 3441: 3438: 3437: 3436: 3433: 3431: 3428: 3426: 3423: 3421: 3418: 3416: 3412: 3411: 3407: 3406: 3403: 3402: 3398: 3394: 3391: 3390: 3389: 3388: 3384: 3380: 3376: 3375:Rhinoscleroma 3373: 3372: 3371: 3370: 3366: 3365: 3363: 3361: 3357: 3354: 3351: 3346: 3342: 3339: 3337: 3333: 3321: 3318: 3317: 3316: 3315: 3311: 3307: 3305: 3304: 3300: 3296: 3293: 3292: 3291: 3290: 3286: 3282: 3279: 3278: 3277: 3276: 3272: 3271: 3269: 3267: 3263: 3251: 3248: 3247: 3246: 3245: 3241: 3237: 3234: 3233: 3232: 3231: 3226: 3225: 3221: 3220: 3218: 3215: 3210: 3202: 3199: 3198: 3197: 3196: 3192: 3191: 3189: 3187: 3183: 3175: 3171: 3167: 3164: 3163: 3162: 3161: 3157: 3156: 3154: 3152: 3148: 3145: 3143: 3139: 3136: 3134: 3130: 3114: 3110: 3107: 3106: 3105: 3104: 3100: 3096: 3093: 3092: 3091: 3087: 3083: 3079: 3076: 3075: 3074: 3073: 3069: 3065: 3062: 3061: 3060: 3059: 3054: 3053:Bartonellosis 3051: 3050: 3048: 3046: 3042: 3034: 3031: 3030: 3029: 3028: 3024: 3023: 3021: 3019: 3015: 3012: 3010: 3006: 2994: 2991: 2990: 2989: 2988: 2984: 2980: 2977: 2976: 2975: 2974: 2970: 2966: 2962: 2959: 2958: 2957: 2956: 2951: 2948: 2947: 2945: 2943: 2939: 2923: 2920: 2919: 2918: 2917: 2913: 2912: 2910: 2908: 2904: 2896: 2893: 2892: 2891: 2890: 2886: 2882: 2879: 2878: 2877: 2876: 2872: 2871: 2869: 2867: 2863: 2855: 2853: 2849: 2848: 2847: 2846: 2842: 2838: 2835: 2834: 2833: 2832: 2828: 2824: 2821: 2820: 2819: 2818: 2814: 2810: 2807: 2806: 2805: 2804: 2800: 2796: 2793: 2792: 2791: 2790: 2786: 2782: 2779: 2778: 2777: 2776: 2772: 2768: 2765: 2764: 2763: 2762: 2758: 2754: 2751: 2750: 2749: 2748: 2744: 2740: 2737: 2736: 2735: 2734: 2730: 2729: 2727: 2725: 2721: 2718: 2716: 2710: 2702: 2698: 2694: 2691: 2690: 2689: 2688: 2684: 2680: 2679:Murine typhus 2677: 2676: 2675: 2674: 2670: 2669: 2667: 2665: 2661: 2658: 2655: 2654:Rickettsioses 2649: 2645: 2642: 2640: 2639:Rickettsiales 2636: 2633: 2631: 2627: 2623: 2619: 2612: 2607: 2605: 2600: 2598: 2593: 2592: 2589: 2576: 2573: 2569: 2568: 2564: 2563: 2560: 2556: 2549: 2545: 2544: 2540: 2538: 2534: 2533: 2529: 2527: 2523: 2522: 2518: 2514: 2512: 2508: 2507: 2503: 2499: 2498: 2495: 2490: 2486: 2479: 2470: 2469: 2461: 2459: 2457: 2453: 2448: 2444: 2439: 2434: 2430: 2426: 2422: 2415: 2412: 2406: 2403: 2398: 2392: 2388: 2384: 2383: 2378: 2372: 2370: 2366: 2361: 2355: 2351: 2344: 2341: 2336: 2330: 2326: 2319: 2316: 2311: 2309:1-84415-026-7 2305: 2301: 2294: 2291: 2286: 2280: 2276: 2269: 2266: 2254: 2250: 2244: 2241: 2236: 2232: 2228: 2224: 2220: 2216: 2212: 2205: 2202: 2197: 2193: 2189: 2185: 2180: 2175: 2172:(3): 229–34. 2171: 2167: 2163: 2156: 2153: 2148: 2144: 2140: 2136: 2132: 2125: 2122: 2117: 2113: 2108: 2103: 2099: 2095: 2091: 2087: 2083: 2076: 2073: 2068: 2067: 2062: 2056: 2053: 2048: 2044: 2038: 2035: 2024:on 2009-05-06 2023: 2019: 2013: 2009: 2005: 1998: 1995: 1990: 1986: 1982: 1978: 1974: 1970: 1966: 1962: 1955: 1952: 1947: 1943: 1939: 1935: 1931: 1927: 1920: 1917: 1912: 1908: 1904: 1897: 1894: 1889: 1885: 1880: 1875: 1871: 1867: 1863: 1856: 1854: 1850: 1845: 1841: 1836: 1831: 1828:(6): 1538–9. 1827: 1823: 1819: 1812: 1809: 1804: 1800: 1795: 1790: 1786: 1782: 1778: 1774: 1770: 1763: 1760: 1755: 1751: 1747: 1743: 1739: 1735: 1731: 1727: 1720: 1717: 1712: 1708: 1703: 1698: 1694: 1690: 1686: 1682: 1678: 1671: 1668: 1663: 1659: 1654: 1649: 1645: 1641: 1637: 1633: 1629: 1625: 1621: 1614: 1611: 1606: 1602: 1597: 1592: 1588: 1584: 1580: 1578: 1569: 1566: 1561: 1557: 1553: 1549: 1545: 1541: 1537: 1533: 1525: 1522: 1517: 1513: 1508: 1503: 1499: 1495: 1492:(10): 3465–. 1491: 1487: 1483: 1476: 1473: 1468: 1464: 1459: 1454: 1450: 1446: 1442: 1435: 1432: 1427: 1423: 1418: 1413: 1409: 1405: 1401: 1394: 1391: 1386: 1382: 1378: 1374: 1367: 1364: 1359: 1355: 1351: 1347: 1343: 1339: 1335: 1331: 1324: 1321: 1316: 1312: 1308: 1304: 1300: 1296: 1292: 1285: 1282: 1277: 1273: 1268: 1263: 1259: 1255: 1251: 1244: 1241: 1236: 1232: 1228: 1224: 1220: 1216: 1209: 1206: 1201: 1197: 1192: 1187: 1183: 1179: 1176:(6): 1128–l. 1175: 1171: 1167: 1160: 1157: 1152: 1148: 1144: 1140: 1136: 1132: 1129:(3): 568–73. 1128: 1124: 1117: 1114: 1109: 1105: 1101: 1097: 1093: 1089: 1082: 1080: 1078: 1074: 1069: 1065: 1060: 1055: 1051: 1047: 1044:(3): 368–70. 1043: 1039: 1035: 1028: 1026: 1022: 1017: 1013: 1009: 1005: 1001: 998:(2): 148–50. 997: 993: 989: 982: 979: 974: 970: 966: 962: 958: 954: 950: 946: 939: 936: 931: 927: 923: 919: 915: 911: 907: 903: 896: 893: 888: 884: 880: 876: 872: 868: 865:(4): 363–70. 864: 860: 852: 849: 844: 840: 835: 830: 826: 822: 819:(2): 256–62. 818: 814: 810: 803: 800: 796: 792: 789: 784: 781: 776: 772: 767: 762: 758: 754: 750: 743: 740: 735: 731: 726: 721: 717: 713: 709: 705: 701: 694: 691: 686: 682: 678: 674: 670: 666: 662: 658: 657:J Med Entomol 654: 647: 644: 639: 635: 630: 625: 620: 615: 611: 607: 603: 596: 593: 589: 584: 582: 578: 573: 569: 565: 561: 557: 553: 549: 545: 538: 535: 530: 523: 520: 513: 509: 506: 505: 501: 499: 497: 491: 489: 484: 482: 478: 473: 469: 465: 461: 457: 453: 449: 444: 442: 441:Burma theatre 438: 434: 430: 426: 418: 415:photographer 414: 413: 408: 403: 396: 394: 392: 388: 384: 381: 377: 372: 369: 365: 361: 357: 352: 346: 344: 342: 338: 334: 333:Ciprofloxacin 330: 326: 322: 318: 314: 309: 303: 301: 299: 294: 292: 288: 283: 281: 276: 272: 268: 264: 256: 254: 250: 246: 244: 240: 239: 233: 231: 227: 226: 221: 213: 211: 209: 205: 201: 197: 193: 189: 185: 181: 177: 173: 169: 165: 161: 157: 153: 145: 143: 141: 140: 135: 134: 130: 126: 122: 117: 115: 112: 108: 105: 104:Gram-negative 101: 100: 96: 92: 89:is a form of 88: 84: 76: 73: 71: 67: 64: 63: 58: 54: 49: 45: 41: 36: 30: 19: 5121:Malakoplakia 5047:Folliculitis 4971:Unspecified 4943:Lyme disease 4880:Helicobacter 4879: 4854: 4803: 4790: 4777: 4734: 4715:Gonococcemia 4626: 4606:Trench fever 4586:Scrub typhus 4585: 4526: 4447: 4439: 4431: 4391:Buruli ulcer 4360: 4335: 4305:Gas gangrene 4294: 4278: 4252: 4225: 4195: 4120:Helicobacter 4119: 4111: 4097:Peptic ulcer 4089: 4071: 4036: 4024: 3997: 3977: 3957: 3950: 3941: 3933: 3913: 3906: 3899: 3892: 3878: 3871:Vibrionaceae 3851: 3824: 3806: 3773: 3753: 3737: 3717: 3703: 3689: 3681: 3669: 3632: 3618: 3600: 3593: 3587: 3557: 3524: 3495: 3489: 3480: 3472: 3448: 3408: 3399: 3385: 3367: 3308: 3301: 3287: 3273: 3242: 3228: 3222: 3213: 3193: 3158: 3142:Neisseriales 3101: 3089: 3085: 3078:Trench fever 3070: 3056: 3025: 3018:Brucellaceae 2985: 2971: 2965:Anaplasmosis 2953: 2950:Ehrlichiosis 2914: 2895:Scrub typhus 2894: 2887: 2873: 2851: 2843: 2829: 2815: 2801: 2787: 2773: 2759: 2745: 2731: 2685: 2671: 2620:-associated 2565: 2541: 2530: 2515: 2500: 2466: 2431:(2): 162–5. 2428: 2424: 2414: 2405: 2381: 2349: 2343: 2324: 2318: 2299: 2293: 2274: 2268: 2257:. 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Retrieved 2022:the original 2007: 1997: 1964: 1960: 1954: 1932:(5): 570–2. 1929: 1925: 1919: 1910: 1906: 1896: 1872:(5): 955–9. 1869: 1865: 1825: 1821: 1811: 1776: 1772: 1762: 1732:(9): 947–9. 1729: 1725: 1719: 1684: 1680: 1670: 1627: 1623: 1613: 1586: 1582: 1576: 1568: 1535: 1531: 1524: 1489: 1485: 1475: 1448: 1444: 1434: 1407: 1403: 1393: 1379:(3): 580–3. 1376: 1372: 1366: 1333: 1329: 1323: 1301:(5): 556–9. 1298: 1294: 1290: 1284: 1257: 1253: 1243: 1221:(2): 400–6. 1218: 1214: 1208: 1173: 1169: 1159: 1126: 1122: 1116: 1094:(4): 425–8. 1091: 1087: 1041: 1037: 1016:the original 995: 991: 981: 973:the original 955:(6): 404–5. 952: 948: 938: 930:the original 912:(3): 207–8. 909: 905: 895: 862: 858: 851: 816: 812: 802: 783: 759:(1): 11–21. 756: 752: 742: 707: 703: 693: 660: 656: 652: 646: 609: 605: 595: 547: 543: 537: 528: 522: 492: 485: 472:Kokoda Track 445: 433:World War II 422: 410: 385: 379: 373: 353: 350: 329:azithromycin 317:tetracycline 310: 307: 295: 284: 263:dengue fever 260: 251: 247: 236: 234: 223: 217: 200:encephalitis 184:splenomegaly 172:hemorrhaging 167: 149: 137: 131: 118: 97: 86: 83:Scrub typhus 82: 81: 60: 38:Scrub typhus 29: 5126:Pyomyositis 4834:Shigellosis 4804:Pseudomonas 4728:Melioidosis 4694:Oroya fever 4684:Brucellosis 4516:Nocardiosis 4326:Listeriosis 4296:Clostridium 3942:Pseudomonas 3690:Haemophilus 3671:Haemophilus 3626:Yersiniosis 3577:Shigellosis 3281:Melioidosis 3090:B. quintana 3086:B. henselae 3033:Brucellosis 2468:El Mercurio 550:(2): 92–8. 417:George Silk 368:cotton rats 341:miscarriage 337:stillbirths 313:doxycycline 267:paratyphoid 243:Solomon Sea 204:myocarditis 196:Pneumonitis 87:bush typhus 43:Other names 5171:Categories 5014:Paronychia 5009:Cellulitis 4882:cellulitis 4793:cellulitis 4733:Cutaneous 4337:Mycoplasma 4287:Erythrasma 4260:Erysipelas 4251:Cutaneous 4122:cellulitis 3705:H. ducreyi 3692:meningitis 3214:ungrouped: 2907:Flea-borne 2866:Mite-borne 2724:Tick-borne 2543:DiseasesDB 2259:2022-06-21 2141:(1): 1–6. 2028:2008-10-03 514:References 464:New Guinea 325:Rifampicin 192:Leukopenia 170:can cause 133:Rickettsia 5004:Carbuncle 4857:infection 4855:Aeromonas 4849:Chancroid 4773:Tularemia 4737:infection 4719:Gonorrhea 4629:infection 4529:infection 4450:infection 4442:infection 4434:infection 4255:infection 4187:Bacillota 4039:infection 4037:Aeromonas 3944:infection 3859:Tularemia 3711:Chancroid 3483:infection 3465:Slow/weak 3379:Pneumonia 3320:Pertussis 3201:Gonorrhea 2854:infection 2567:eMedicine 2010:. Mosby. 1754:207384950 1644:1469-493X 572:206172576 387:Dora Lush 374:Enormous 304:Treatment 257:Diagnosis 70:Specialty 5187:Zoonoses 5089:Gangrene 5040:Pyoderma 4973:pathogen 4903:Syphilis 4898:Syphilid 4747:Glanders 4552:Gram -ve 4236:Impetigo 4211:Impetigo 4178:Gram +ve 3567:flexneri 3481:Serratia 3295:Glanders 2575:ped/2710 2572:derm/841 2447:12389941 2235:19220144 2196:41165633 2188:10338191 2116:20248030 2086:Br Med J 1989:29646085 1981:11009140 1946:15307429 1888:17123995 1803:10543774 1746:19011809 1711:17638700 1662:30246875 1605:12685633 1560:23316592 1516:18716229 1467:17172374 1426:16968938 1358:24087729 1350:14501995 1276:17205447 1151:44692835 1143:14014756 1068:20207857 1012:18362409 969:17186964 926:16785710 887:25778287 879:16762116 843:16494751 791:Archived 775:11226850 734:27928073 677:11296840 638:29590177 564:18281226 502:See also 479:and the 280:serology 220:chiggers 156:headache 139:Orientia 125:pathogen 5069:Ecthyma 4980:Abscess 4908:Chancre 4824:Q fever 4411:Leprosy 4363:related 3886:Cholera 3832:Q fever 3435:O104:H4 3430:O157:H7 3084:Either 2713:Spotted 2387:297–298 2147:6789455 2107:2053023 1844:9868680 1702:2043199 1653:6485465 1552:8676722 1507:2566087 1385:9185274 1315:8940989 1235:3128129 1200:6809786 1108:9373640 1059:2829893 834:3373100 725:5154431 685:8133110 629:5891077 450:in the 448:Oceania 431:during 397:History 356:vaccine 347:Vaccine 5177:Typhus 5064:Pimple 4839:Plague 4504:Others 4319:Others 3608:Plague 3571:boydii 3563:sonnei 2664:Typhus 2537:D01261 2445:  2393:  2356:  2331:  2306:  2281:  2233:  2194:  2186:  2145:  2114:  2104:  2014:  1987:  1979:  1961:Lancet 1944:  1886:  1842:  1801:  1791:  1752:  1744:  1709:  1699:  1660:  1650:  1642:  1603:  1558:  1550:  1532:Lancet 1514:  1504:  1465:  1424:  1383:  1356:  1348:  1313:  1274:  1233:  1198:  1191:272264 1188:  1149:  1141:  1106:  1066:  1056:  1010:  967:  924:  885:  877:  841:  831:  773:  732:  722:  683:  675:  636:  626:  570:  562:  429:Ceylon 407:Papuan 319:, but 275:eschar 269:, and 230:eschar 214:Causes 202:, and 186:, and 180:eschar 162:, and 123:, its 121:typhus 111:family 91:typhus 4923:Bejel 4918:Pinta 4891:Other 4761:Gamma 4569:Alpha 4005:HACEK 3785:HACEK 3725:HACEK 3236:HACEK 2715:fever 2548:31715 2526:081.2 2511:A75.3 2192:S2CID 1985:S2CID 1794:89570 1750:S2CID 1556:S2CID 1354:S2CID 1147:S2CID 883:S2CID 681:S2CID 568:S2CID 425:Burma 160:cough 152:fever 129:genus 4913:Yaws 4708:Beta 3551:H2S− 3517:H2S+ 3508:Lac− 3360:Lac+ 2532:MeSH 2521:9-CM 2443:PMID 2391:ISBN 2354:ISBN 2329:ISBN 2304:ISBN 2279:ISBN 2231:PMID 2184:PMID 2143:PMID 2112:PMID 2012:ISBN 1977:PMID 1942:PMID 1884:PMID 1840:PMID 1799:PMID 1742:PMID 1707:PMID 1658:PMID 1640:ISSN 1628:2018 1601:PMID 1548:PMID 1512:PMID 1463:PMID 1422:PMID 1381:PMID 1346:PMID 1311:PMID 1272:PMID 1231:PMID 1196:PMID 1139:PMID 1104:PMID 1064:PMID 1008:PMID 965:PMID 922:PMID 875:PMID 839:PMID 771:PMID 730:PMID 673:PMID 634:PMID 560:PMID 427:and 412:Life 339:and 327:and 174:and 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Index

Tsutsugamushi fever

Orientia tsutsugamushi
Specialty
Infectious disease
typhus
intracellular parasite
Orientia tsutsugamushi
Gram-negative
α-proteobacterium
family
Rickettsiaceae
typhus
pathogen
genus
Rickettsia
Orientia
fever
headache
cough
gastrointestinal symptoms
hemorrhaging
intravascular coagulation
eschar
splenomegaly
lymphadenopathies
Leukopenia
Pneumonitis
encephalitis
myocarditis

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