Knowledge (XXG)

Ventriculomegaly

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Many conditions associated with ventriculomegaly can be defined prior to birth, but the possibility remains of other anomalies (either structural, chromosomal or genetic) only being identified later in pregnancy or after birth. Ventriculomegaly associated with abnormal findings and other structural
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become dilated. The most common definition uses a width of the atrium of the lateral ventricle of greater than 10 mm. This occurs in around 1% of pregnancies. When this measurement is between 10 and 15 mm, the ventriculomegaly may be described as mild to moderate. When the measurement is
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This diagnosis is generally found in routine fetal anomaly scans at 18–22 weeks gestation. It is one of the more common abnormal brain findings on prenatal ultrasound, occurring in around 1–2 per 1,000 pregnancies. In many cases of mild ventriculomegaly, however, there is resolution of
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Falip, Céline; Blanc, Nathalie; Maes, Emmanuelle; Zaccaria, Isabelle; Oury, Jean François; Sebag, Guy; Garel, Catherine (28 August 2007). "Postnatal clinical and imaging follow-up of infants with prenatal isolated mild ventriculomegaly: a series of 101 cases".
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Breeze, Andrew C.G.; Dey, Prakash K.; Lees, Christoph C.; Hackett, Gerald A.; Smith, Gordon C.S.; Murdoch, Edile M. (1 January 2005). "Obstetric and neonatal outcomes in apparently isolated mild fetal ventriculomegaly".
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Breeze, Andrew C. G.; Alexander, Peta M. A.; Murdoch, Edile M.; Missfelder-Lobos, Hannah H.; Hackett, Gerald A.; Lees, Christoph C. (February 2007). "Obstetric and neonatal outcomes in severe fetal ventriculomegaly".
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Although evaluation of lateral ventricles dimensions is decisive for establishing a diagnosis of ventriculomegaly, the shape of the ventricular system, including that of the frontal horns, is also important.
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is being considered as part of the assessment of pregnancies complicated by fetal ventriculomegaly, and appears to be important in the postnatal assessment of affected children.
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Cardoza, J D; Goldstein, R B; Filly, R A (December 1988). "Exclusion of fetal ventriculomegaly with a single measurement: the width of the lateral ventricular atrium".
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Glenn, OA; Barkovich, AJ (September 2006). "Magnetic resonance imaging of the fetal brain and spine: an increasingly important tool in prenatal diagnosis, part 1".
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Diagnosis and Evaluation for Ventriculomegaly- Center for Prenatal Pediatrics at Columbia University Medical Center/ NY Presbyterian
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Salomon, L. J.; Bernard, J. P.; Ville, Y. (July 2007). "Reference ranges for fetal ventricular width: a non-normal approach".
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Glonek, M; Kedzia, A; Derkowski, W (July 2003). "Prenatal assessment of ventriculomegaly: an anatomical study".
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Enlargement of the ventricles may occur for a number of reasons, such as loss of brain volume (perhaps due to
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Signorelli, M.; Tiberti, A.; Valseriati, D.; Molin, E.; Cerri, V.; Groli, C.; Bianchi, U. A. (January 2004).
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Gaglioti, P.; Danelon, D.; Bontempo, S.; Mombrò, M.; Cardaropoli, S.; Todros, T. (April 2005).
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Ventriculomegaly is also known to be associated with other malformations such as
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greater than 15mm, the ventriculomegaly may be classified as more severe.
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Achiron, R.; Schimmel, M.; Achiron, A.; Mashiach, S. (1 March 1993).
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Sandu C, Burloiu CM, Barca DG, Magureanu SA, Craiu DC (2019).
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and with other anomalies have an increased risk of having a
577:"Ketogenic Diet in Patients with GLUT1 Deficiency Syndrome" 353:"Fetal cerebral ventriculomegaly: outcome in 176 cases" 992: 959: 934: 909: 848: 808: 799: 741: 693: 29:is a brain condition that mainly occurs in the 69:, or may have become obstructed by infection, 667: 647:UCSF Fetal Treatment Center: Ventriculomegaly 8: 623:: CS1 maint: multiple names: authors list ( 266: 264: 805: 674: 660: 652: 346: 344: 164:Progressive multifocal leukoencephalopathy 600: 453: 368: 324: 49:), or impaired outflow or absorption of 16:Increased size of the lateral ventricles 442:Ultrasound in Obstetrics and Gynecology 357:Ultrasound in Obstetrics and Gynecology 313:Ultrasound in Obstetrics and Gynecology 235:Ultrasound in Obstetrics and Gynecology 190: 81:ventriculomegaly during the pregnancy. 616: 135:Ventriculomegaly occurs in those with 7: 117:malformations, often has an adverse 326:10.1046/j.1469-0705.1993.03020089.x 479:American Journal of Neuroradiology 14: 212:10.1148/radiology.169.3.3055034 109:abnormality, including that of 91:agenesis of the corpus callosum 1: 593:10.26574/maedica.2019.14.2.93 395:Journal of Perinatal Medicine 154:Normal pressure hydrocephalus 101:. Fetuses with both isolated 59:normal pressure hydrocephalus 61:associated with conspicuous 53:from the ventricles, called 1037: 126:magnetic resonance imaging 979:Interventricular foramina 519:10.1007/s00247-007-0582-2 137:GLUT1 deficiency syndrome 830:Inferior medullary velum 818:Superior medullary velum 550:Medical Science Monitor 179:Ventricular-brain ratio 67:congenitally malformed 23: 22: 791:Posterior commissure 407:10.1515/JPM.2005.043 124:Increasingly, fetal 969:Blood–brain barrier 961:Cerebrospinal fluid 879:Hypoglossal trigone 776:Hypothalamic sulcus 759:Infundibular recess 716:Collateral eminence 507:Pediatric Radiology 51:cerebrospinal fluid 984:Perilymphatic duct 764:Suprapineal recess 695:Lateral ventricles 683:Ventricular system 274:Prenatal Diagnosis 35:lateral ventricles 24: 1008: 1007: 974:Cerebral aqueduct 955: 954: 859:Facial colliculus 786:Subfornical organ 733:Septum pellucidum 169:Vascular dementia 149:Neuroinflammation 1028: 1000:Ventriculomegaly 806: 801:Fourth 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Index


fetus
lateral ventricles
infection
infarction
cerebrospinal fluid
hydrocephalus
normal pressure hydrocephalus
brain sulcus
congenitally malformed
hemorrhage
tumor
agenesis of the corpus callosum
spina bifida
heart defects
chromosomal
Down syndrome
prognosis
magnetic resonance imaging
GLUT1 deficiency syndrome
Neuroinflammation
Normal pressure hydrocephalus
Hydrocephalus
Progressive multifocal leukoencephalopathy
Vascular dementia
Ventriculitis
Ventricular-brain ratio
doi
10.1148/radiology.169.3.3055034
PMID

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