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which prevented tumours from developing. As a result of their "pioneering research on the causes of cancer resistance in naked mole-rats," Gorbunova and
Seluanov won the 2009 Cozzarelli Prize. She also received a 2010 Glenn Award for Research in Biological Mechanisms of Aging for "groundbreaking work
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Throughout her tenure at the
University of Rochester, Gorbunova's research team continued to focus on the naked mole rat as a key to understanding cancer resistance among animals. In 2013, Gorbunova and Seluanov identified high molecular weight hyaluronan as the key mediator of cancer resistance in
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had a more significant correlation with body mass than longevity. She revealed that one's body mass caused a greater risk of cancer than one's lifespan. She continued her focus on cancer cells and co-developed a gene that produced a thousand times more protein in cancer cells than in healthy cells.
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and replaced it with a marker protein DNA which killed breast cancer, fibrosarcoma, and cervical cancer cells with minimal effect on normal cells. Following this discovery, Gorbunova focused her cancer-fighting experiments on the
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to suggest treatments for diseases in humans. She later received a grant to explore potential targets of treatments and therapeutics for neurodegenerative diseases. Gorbunova also stepped down as co-editor of the journal
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to study the evolution of tumour suppressor mechanisms in rodents. Two years later, Gorbunova conducted a study which discovered that the enzyme
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Tian, X.; Azpurua, J.; Hine, C.; Vaidya, A.; Myakishev-Rempel, M.; Ablaeva, J.; Mao, Z.; Nevo, E.; Gorbunova, V.; Seluanov, A. (July 18, 2013).
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that has the potential to shed light on the biological process of ageing, and could benefit from an infusion of unexpected funding."
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During the COVID-19 pandemic, Gorbunova's research team compared the longevity and virus resistance mechanisms within
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along with the remaining three editors in chiefs, due to their increased workloads without assistance.
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the naked mole rat. As a result of their work, the rodent was named the
Vertebrate of the Year by
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415:"High molecular weight hyaluronan mediates the cancer resistance of the naked mole-rat"
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326:"Modified Gene Targets Cancer Cells a Thousand Times More Often Than Healthy Cells"
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In 2004, Gorbunova and Andrei
Seluanov established a research laboratory at the
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230:"The Awardee of the 2014 Prince Hitachi Prize for Comparative Oncology"
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573:"Connecting the dots between aging, Alzheimer's, and 'junk DNA'"
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529:"Biologist Vera Gorbunova to lead 5-year project on longevity"
348:"Scientists Discover Gene that 'Cancer-Proofs' Rodent's Cells"
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is a biologist. As the Doris Johns Cherry
Professor at the
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project to explore the factors responsible for longevity.
392:"Two University of Rochester Biologists Win Glenn Awards"
596:"Editors Step Down From Journal, Citing Lack of Support"
304:"Blame Our Evolutionary Risk of Cancer on Our Body Mass"
507:"Vera Gorbunova appointed Doris Johns Cherry Professor"
485:"Gorbunova earns award for work with naked mole rats"
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258:. Weizmann Institute of Science. January 10, 1999
619:"A Homely Rodent May Hold Cancer-Fighting Clues"
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99:as the key mediator of cancer resistance in the
370:"Gorbunova and Seluanov Win Cozzarelli Prize"
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465:. University of Rochester. December 23, 2013
328:. University of Rochester. December 18, 2008
509:. University of Rochester. November 6, 2014
350:. University of Rochester. October 27, 2009
306:. University of Rochester. December 6, 2006
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575:. University of Rochester. March 16, 2022
531:. University of Rochester. April 23, 2014
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372:. University of Rochester. April 23, 2010
205:Gorbunova is married to fellow biologist
681:Saint Petersburg State University alumni
394:. University of Rochester. July 21, 2010
553:. University of Rochester. July 8, 2020
551:"Bats offer clues to treating COVID-19"
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594:Flaherty, Colleen (August 30, 2022).
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686:Weizmann Institute of Science alumni
280:. McGill University. Archived from
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487:. Campus Times. November 14, 2013
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617:Zimmer, Carl (June 19, 2013).
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463:"Vertebrate of the Year!"
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649:publications indexed by
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119:and her Ph.D. at the
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278:"Hekimi Lab: Alumni"
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113:Bachelor of Science
47:Academic background
623:The New York Times
598:. Inside Higher Ed
256:"Playing the Odds"
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193:Aging Cell
141:telomerase
115:degree at
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131:Career
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