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Normally, the myofibroblasts appear in the initial wound healing processes and generate contractile forces to pull both edges of an open wound until it disappears by apoptosis. But as an altered regulation of myofibroblast disappearance, they remain in the dermis and continuously contract the scar,
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Shin D1, Minn KW. (2004). "The effect of myofibroblast on contracture of hypertrophic scar".
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