Knowledge

Bufotoxin

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Symptoms may vary depending on certain factors such as the size and age of the victim. Other than the first, more benign symptoms (such as a tingling or burning sensation in the eyes, mucous membranes, or in exposed wounds), the most frequently described symptoms in the medical literature are :
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Poisoning from toad toxin is rare but can kill. It can occur when someone drinks toad soup, eats toad meat or toad eggs, or swallows live toads on a bet. It can also happen when someone deliberately takes commercial substances made with toad toxins. These go under names including "Kyushin", "Chan
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One epileptic episode caused by Bufotoxins was observed in a 5-year old child, minutes after they had placed a Bufo alvarius in their mouth. The child was successfully treated with diazepam and phenobarbital.
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In extreme cases following ingestion of mucus or skin of the toad, death generally occurs within 6 and 24 hours. Victims surviving past 24 hours generally will recover.
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Chemical structure of one of the main components of bufotoxin, a conjugate of bufagin with suberylarginine. This component is itself sometimes called bufotoxin.
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Do not translate text that appears unreliable or low-quality. If possible, verify the text with references provided in the foreign-language article.
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Kißmer, B.; Wichtl, M. (1986). "Bufadienolide aus Samen von Helleborus odorus" [Bufadienolides from the Seeds of Helleborus odorus].
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family) and other amphibians, and in some plants and mushrooms. The exact composition varies greatly with the specific source of the toxin.
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Siperstein MD, Murray AW, Titus E (March 1957). "Biosynthesis of cardiotonic sterols from cholesterol in the toad, Bufo marinus".
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Su" (marketed as a painkiller, topical anesthetic or cardiac treatment), "Rockhard" and "Love Stone" (marketed as aphrodisiacs).
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purposes by some individuals. However, the practice of using these substances derived from animals for spiritual experiences or
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Despite being a frequent target for milking, these toads still carry cardio toxic bufotoxins which have been linked to deaths.
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of caught, washed toads for a white venom and drying; the final dried poison is usually brown, with a chunk or flake form.
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Content in this edit is translated from the existing French Knowledge article at ]; see its history for attribution.
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Toxic and Hallucinogenic Mushroom Poisoning: A Handbook for Physicians and Mushroom Hunters
490:"Chan Su" (literally "toad venom") is often adulterated with standard painkillers, such as 2368: 2273: 1868: 1523: 1420: 1265: 1240: 1125: 1053: 1039: 575: 233:
The toxic substances found in toads can be divided by chemical structure in two groups:
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note: some toxins are produced by lower species and pass through intermediate species
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Chen KK, Kovaríková A (December 1967). "Pharmacology and toxicology of toad venom".
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Trakulsrichai, S; Chumvanichaya, K; Sriapha, C; Tongpoo, A; Wananukul, W (2020).
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Hitt M, Ettinger DD. Toad toxicity. N Engl J Med ; 1986 ; 314:1517
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to the source of your translation. A model attribution edit summary is
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The effects of the bufotoxins in these toads are not well understood.
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concerns about the potential suffering inflicted on the animal.
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combined by weight. The extract is obtained by squeezing the
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Kuo, HY; Hsu, CW; Chen, JH; Wu, YL; Shen, YS (March 2007).
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to this template: there are already 1,502 articles in the
972:"Toad Poisoning: Clinical Characteristics and Outcomes" 436:, is often found in certain Chinese folk remedies. The 428:
Extract from the skin of certain Asian toads, such as
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Some authors have also used the term 79: 7: 1034:Anaxyrus boreas boreas - Boreal Toad 675:. New York: Van Nostrand Reinhold. 293:Toads known to secrete bufotoxins. 1347:Staphylococcal Enterotoxin B (SEB) 897:Cartwright, Megan (29 June 2015). 733:Journal of Pharmaceutical Sciences 502:. It may be ingested or injected. 14: 784:. Berlin: Springer Berlin. 2013. 2399: 2398: 23: 1431:Extracellular adenylate cyclase 941:10.1016/j.forsciint.2009.02.006 222:to describe the conjugate of a 929:Forensic Science International 454: 445: 110:You may also add the template 1: 1583:Fibronectin binding protein A 646:10.1016/0003-9861(57)90254-0 112:{{Translated|fr|Bufotoxine}} 1324:Staphylococcus aureus alpha 1302:Panton–Valentine leukocidin 258:-related substances (e.g., 154:, skin, and poison of many 82:will aid in categorization. 16:Class of chemical compounds 2451: 1342:Toxic shock syndrome toxin 847:Emergency Medicine Journal 286: 57:Machine translation, like 2394: 2381: 2239:(+)-Allopumiliotoxin 267A 1287: 572:(starting at extremities) 346:Melanophryniscus moreirae 297:Toads frequently "milked" 289:List of poisonous animals 38:the corresponding article 1632:beta-Nitropropionic acid 506:Symptoms of Intoxication 262:), are sought after for 1416:Heat-labile enterotoxin 1407:heat-stable enterotoxin 859:10.1136/emj.2006.044602 178:Bufotoxins can contain 121:For more guidance, see 1525:Bacillus thuringiensis 745:10.1002/jps.2600561202 463: 175: 139:are a family of toxic 1036:, californiaherps.com 710:10.1055/s-2007-969103 596:loss of consciousness 430:Bufo bufo gargarizans 339:Nannophryne variegata 173: 123:Knowledge:Translation 94:copyright attribution 1426:Pseudomonas exotoxin 989:10.2147/TCRM.S272863 272:responsible drug use 540:bundle branch block 534:atrial fibrillation 391:Anaxyrus americanus 2342:Alpha-Bungarotoxin 1512:Lipopolysaccharide 1470:Pore-forming toxin 827:蟾酥 bufonis venenum 601:respiratory arrest 591:anaphylactic shock 526:cardiac arrhythmia 434:Bufo melanostictus 405:Bufo melanostictus 242:cardiac glycosides 176: 102:interlanguage link 2425:Alpha-Amino acids 2412: 2411: 2377: 2376: 2347:Beta-Bungarotoxin 2291:Pumiliotoxin 251D 2185: 2184: 1591: 1590: 1578:Clumping factor A 1498: 1497: 1382: 1381: 1355: 1354: 1274: 1273: 682:978-0-442-24580-1 367:Incilius alvarius 332:Rhinella diptycha 325:Rhinella arenarum 313:Incilius alvarius 204:dehydrobufotenine 134: 133: 50: 46: 2442: 2430:Amphibian toxins 2402: 2401: 2330: 2286:Histrionicotoxin 2232: 2206: 2198: 2150: 2104:Alpha-latrotoxin 2092: 1986: 1978: 1710:Sterigmatocystin 1662:, Fumonisin B3, 1626:epsilon-amanitin 1545:B. thuringiensis 1374:Diphtheria toxin 1317: 1285: 1254: 1170: 1162: 1153: 1142: 1133: 1070: 1063: 1056: 1047: 1021: 1018: 1012: 1011: 1001: 991: 967: 961: 960: 920: 914: 913: 911: 909: 894: 881: 880: 870: 838: 829: 824: 805:国家药典委员会 (2015). 802: 796: 795: 778: 757: 756: 728: 722: 721: 693: 687: 686: 674: 664: 658: 657: 629: 456: 447: 113: 107: 81: 80:|topic= 78:, and specifying 63:Google Translate 48: 44: 27: 26: 19: 2450: 2449: 2445: 2444: 2443: 2441: 2440: 2439: 2435:Causes of death 2415: 2414: 2413: 2408: 2390: 2373: 2369:Cardiotoxin III 2325: 2320: 2315: 2227: 2222: 2201: 2193: 2181: 2145: 2140: 2087: 2082: 1981: 1973: 1965: 1869:Resiniferatoxin 1734: 1587: 1569: 1562: 1527:delta endotoxin 1494: 1435: 1421:Pertussis toxin 1389: 1378: 1351: 1313: 1308: 1270: 1266:Listeriolysin O 1252: 1247: 1165: 1147: 1127: 1120: 1074: 1030: 1025: 1024: 1019: 1015: 969: 968: 964: 922: 921: 917: 907: 905: 896: 895: 884: 840: 839: 832: 821: 804: 803: 799: 792: 780: 779: 760: 739:(12): 1535–41. 730: 729: 725: 695: 694: 690: 683: 666: 665: 661: 631: 630: 626: 621: 576:hypersalivation 508: 484: 482:Human poisoning 476:parotoid glands 464:bufonis venenum 426: 412:Rhinella marina 383: 299: 291: 285: 228:suberylarginine 168: 152:parotoid glands 146:or substituted 130: 129: 128: 111: 105: 51: 45:(February 2019) 28: 24: 17: 12: 11: 5: 2448: 2446: 2438: 2437: 2432: 2427: 2417: 2416: 2410: 2409: 2407: 2406: 2395: 2392: 2391: 2389: 2388: 2382: 2379: 2378: 2375: 2374: 2372: 2371: 2366: 2361: 2356: 2351: 2350: 2349: 2344: 2333: 2331: 2317: 2316: 2314: 2313: 2311:Zetekitoxin AB 2308: 2303: 2298: 2293: 2288: 2283: 2278: 2277: 2276: 2271: 2266: 2261: 2256: 2246: 2241: 2235: 2233: 2224: 2223: 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1286: 1283: 1281: 1277: 1267: 1264: 1262: 1261:Anthrax toxin 1259: 1258: 1256: 1250: 1242: 1239: 1238: 1237: 1236: 1232: 1228: 1225: 1223: 1220: 1219: 1218: 1217: 1213: 1209: 1206: 1204: 1201: 1200: 1199: 1198: 1194: 1190: 1187: 1185: 1184:Tetanospasmin 1182: 1181: 1180: 1179: 1175: 1174: 1172: 1168: 1163: 1160: 1158: 1154: 1151: 1149: 1143: 1140: 1138: 1134: 1131: 1129: 1123: 1115: 1112: 1110: 1107: 1105: 1102: 1100: 1097: 1095: 1092: 1090: 1087: 1085: 1082: 1081: 1080: 1077: 1076: 1071: 1066: 1064: 1059: 1057: 1052: 1051: 1048: 1041: 1038: 1035: 1032: 1031: 1027: 1017: 1014: 1009: 1005: 1000: 995: 990: 985: 982:: 1235–1241. 981: 977: 973: 966: 963: 958: 954: 950: 946: 942: 938: 934: 930: 926: 919: 916: 904: 900: 893: 891: 889: 887: 883: 878: 874: 869: 864: 860: 856: 852: 848: 844: 837: 835: 831: 828: 822: 820:9787506773379 816: 812: 808: 801: 798: 793: 787: 783: 777: 775: 773: 771: 769: 767: 765: 763: 759: 754: 750: 746: 742: 738: 734: 727: 724: 719: 715: 711: 707: 703: 700:(in German). 699: 698:Planta Medica 692: 689: 684: 678: 673: 672: 663: 660: 655: 651: 647: 643: 640:(1): 154–60. 639: 635: 628: 625: 618: 616: 613: 607: 604: 602: 599: 597: 594: 592: 589: 587: 584: 582: 579: 577: 574: 571: 568: 566: 563: 561: 560:hallucination 558: 556: 553: 551: 548: 546: 543: 541: 538: 535: 531: 527: 524: 522: 519: 517: 514: 513: 512: 505: 503: 501: 497: 493: 488: 481: 479: 477: 473: 472:resibufogenin 469: 465: 461: 457: 451: 443: 439: 435: 431: 423: 418: 414: 413: 409: 407: 406: 402: 400: 399: 395: 393: 392: 388: 387: 386: 380: 373: 372:Bufo alvarius 369: 368: 364: 363: 362: 359: 355: 354: 350: 348: 347: 343: 341: 340: 336: 334: 333: 329: 327: 326: 322: 319: 318:Bufo alvarius 315: 314: 310: 309: 307: 304: 303: 302: 296: 294: 290: 282: 277: 273: 269: 265: 261: 257: 254: 251: 247: 243: 239: 236: 235: 234: 231: 229: 225: 221: 217: 213: 209: 205: 201: 197: 193: 189: 185: 181: 172: 165: 163: 161: 157: 153: 149: 145: 142: 138: 124: 120: 117: 109: 103: 99: 95: 91: 87: 84: 77: 76:main category 73: 72: 67: 64: 60: 56: 54: 53: 47: 41: 39: 34:You can help 30: 21: 20: 2385: 2364:Calcicludine 2354:Calciseptine 2337:Bungarotoxin 2306:Tarichatoxin 2254:Arenobufagin 2248: 2218:Tetrodotoxin 2177:Tetrodotoxin 2131:Vanillotoxin 2068:Phaiodotoxin 1971:Invertebrate 1894:Solasodamine 1829:Lotaustralin 1664:Fumonisin B4 1660:Fumonisin B2 1656:Fumonisin B1 1642:Cytochalasin 1544: 1524: 1476: 1462: 1456:Superantigen 1448: 1404: 1292:Streptolysin 1233: 1214: 1195: 1176: 1042:, erowid.com 1016: 979: 975: 965: 935:(1): e1–e5. 932: 928: 918: 906:. Retrieved 902: 853:(3): 215–6. 850: 846: 810: 806: 800: 781: 736: 732: 726: 704:(2): 152–3. 701: 697: 691: 670: 662: 637: 633: 627: 614: 610: 509: 496:promethazine 489: 485: 453: 433: 429: 427: 417:Bufo marinus 416: 410: 403: 396: 389: 384: 371: 365: 351: 344: 337: 330: 323: 317: 311: 308:(bufotenin) 300: 292: 268:recreational 240:, which are 232: 219: 200:bufothionine 177: 136: 135: 98:edit summary 89: 69: 43: 35: 2327:Snake venom 2281:Epibatidine 2269:Cinobufagin 2126:Stromatoxin 2073:Imperatoxin 2023:Scyllatoxin 1929:Tagetitoxin 1924:Swainsonine 1914:Solauricine 1879:Solamargine 1874:Scopolamine 1864:Retronecine 1730:Zearalenone 1398:Shiga toxin 1369:Cord factor 1208:Enterotoxin 1203:Alpha toxin 1197:perfringens 1189:Tetanolysin 1167:Clostridium 1104:hepatotoxin 1094:enterotoxin 1084:cardiotoxin 1040:Toad Toxins 545:hypotension 530:ventricular 528:(including 521:bradycardia 492:paracetamol 468:cinobufagin 381:Other toads 264:entheogenic 208:epinephrine 166:Composition 148:tryptamines 2419:Categories 2359:Taicatoxin 2296:Samandarin 2249:Bufotoxins 2213:Ciguatoxin 2191:Vertebrate 2136:Huwentoxin 2116:Cupiennins 2099:Latrotoxin 2043:Kaliotoxin 2013:Margatoxin 2003:Maurotoxin 1944:Toxalbumin 1934:Tinyatoxin 1919:Strychnine 1904:Solasonine 1899:Solasodine 1884:Solanidine 1804:Falcarinol 1789:Delphinine 1705:Phalloidin 1695:Ochratoxin 1690:Orellanine 1680:Lolitrem B 1647:Ergotamine 1597:Mycotoxins 1441:Mechanisms 1400:/Verotoxin 1337:Exfoliatin 1297:Leukocidin 1114:phototoxin 1109:neurotoxin 619:References 500:diclofenac 424:Extraction 415:(formerly 370:(formerly 316:(formerly 287:See also: 274:may raise 256:tryptamine 137:Bufotoxins 2264:Bufotenin 2259:Bufotalin 2229:Amphibian 2172:Saxitoxin 2162:Eledoisin 2157:Conotoxin 2028:Hefutoxin 1844:Oleandrin 1824:Linamarin 1814:Helenalin 1774:Cicutoxin 1769:Chaconine 1749:Amygdalin 1720:Vomitoxin 1670:Gliotoxin 1652:Fumonisin 1605:Aflatoxin 1568:Virulence 1504:Endotoxin 1235:botulinum 1216:difficile 1126:Bacterial 1099:hemotoxin 1089:cytotoxin 949:0379-0738 825:entries: 807:中华人民共和国药典 570:paralysis 555:tachypnea 398:Bufo bufo 361:5-MeO-DMT 260:bufotenin 250:bufogenin 246:bufotalin 220:bufotoxin 216:serotonin 196:bufotenin 192:bufotalin 180:5-MeO-DMT 160:Bufonidae 116:talk page 68:Consider 40:in French 2404:Category 2167:Onchidal 2147:Mollusca 2058:Bestoxin 2053:Birtoxin 2018:Slotoxin 2008:Agitoxin 1983:Scorpion 1939:Tomatine 1889:Solanine 1834:Mimosine 1809:Gossypol 1794:Divicine 1759:Antiarin 1754:Anisatin 1685:Muscimol 1637:Citrinin 1610:Amatoxin 1556:Cry34Ab1 1484:AB toxin 1478:type III 1390:negative 1148:positive 1137:Exotoxin 1008:33363378 957:19303230 908:22 April 877:17351232 718:84240708 654:13412129 586:vomiting 581:diarrhea 516:paleness 306:5-HO-DMT 184:bufagins 144:lactones 92:provide 2322:Reptile 1784:Daphnin 1779:Coniine 1764:Brucine 1725:Zeranol 1700:Patulin 1547:toxins 1537:Cry3Bb1 1517:Lipid A 1464:type II 1405:E. coli 1157:Bacilli 999:7752649 868:2660035 753:4871915 550:dyspnea 442:Chinese 283:Species 276:ethical 266:and/or 244:(e.g., 224:bufagin 188:bufalin 141:steroid 114:to the 96:in the 42:. 2194:toxins 2089:Spider 2063:BmKAEP 2033:HgeTx1 1974:toxins 1849:Persin 1742:toxins 1570:factor 1551:Cry6Aa 1543:Other 1532:Cry1Ac 1450:type I 1253:Other: 1178:tetani 1128:toxins 1079:Toxins 1006:  996:  955:  947:  875:  865:  817:  788:  751:  716:  679:  652:  455:Chánsū 452:: 450:pinyin 444:: 214:, and 2121:PhTx3 2038:HsTx1 1961:Tutin 1954:Ricin 1949:Abrin 1819:Ledol 1740:Plant 1332:delta 1280:Cocci 1241:Botox 809:[ 714:S2CID 460:Latin 226:with 156:toads 59:DeepL 2203:Fish 2111:CSTX 1388:Gram 1328:beta 1146:Gram 1004:PMID 953:PMID 945:ISSN 910:2021 873:PMID 815:ISBN 786:ISBN 749:PMID 677:ISBN 650:PMID 532:and 498:and 470:and 432:and 90:must 88:You 2078:Pi3 2048:Lq2 1488:AB5 994:PMC 984:doi 937:doi 933:188 863:PMC 855:doi 741:doi 706:doi 642:doi 61:or 2421:: 1658:, 1624:, 1620:, 1616:, 1002:. 992:. 980:16 978:. 974:. 951:. 943:. 931:. 927:. 901:. 885:^ 871:. 861:. 851:24 849:. 845:. 833:^ 761:^ 747:. 737:56 735:. 712:. 702:52 648:. 638:67 636:. 494:, 462:: 458:; 448:; 446:蟾酥 248:, 230:. 210:, 206:, 202:, 198:, 194:, 190:, 186:, 182:, 2329:: 2324:/ 2231:: 2205:: 2149:: 2091:: 1985:: 1666:) 1654:( 1628:) 1612:( 1486:/ 1414:/ 1330:/ 1326:/ 1227:B 1222:A 1169:: 1069:e 1062:t 1055:v 1010:. 986:: 959:. 939:: 912:. 879:. 857:: 823:. 794:. 755:. 743:: 720:. 708:: 685:. 656:. 644:: 536:) 419:) 374:) 320:) 158:( 125:. 118:.

Index

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steroid
lactones
tryptamines
parotoid glands
toads
Bufonidae

5-MeO-DMT
bufagins
bufalin
bufotalin
bufotenin
bufothionine
dehydrobufotenine
epinephrine
norepinephrine
serotonin
bufagin
suberylarginine
bufadienolides

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