31:
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Sluis-Cremer N, Hamamouch N, San Félix A, Velazquez S, Balzarini J, Camarasa MJ (August 2006). "Structure-activity relationships of - 3'-spiro-5' '-(4' '-amino-1' ',2' '-oxathiole-2' ',2' '-dioxide)thymine derivatives as inhibitors of HIV-1 reverse transcriptase dimerization".
288:
versions of alkaline phosphatase were combined, the heterodimeric enzymes formed as a result exhibited a higher level of activity than would be expected based on the relative activities of the parental enzymes. These findings indicated that the dimer structure of the
34:
Cartoon diagram of a dimer of
Escherichia coli galactose-1-phosphate uridylyltransferase (GALT) in complex with UDP-galactose (stick models). Potassium, zinc, and iron ions are visible as purple, gray, and bronze-colored spheres
469:
Filipiuc, Leontina Elena; Ababei, Daniela Carmen; Alexa-Stratulat, Teodora; Pricope, Cosmin
Vasilica; Bild, Veronica; Stefanescu, Raluca; Stanciu, Gabriela Dumitrita; Tamba, Bogdan-Ionel (2021-11-01).
528:
Hehir, Michael J.; Murphy, Jennifer E.; Kantrowitz, Evan R. (2000). "Characterization of
Heterodimeric Alkaline Phosphatases from Escherichia coli: An Investigation of Intragenic Complementation".
574:
8. Hjorleifsson, Jens GuMundur, and Bjarni
Asgeirsson. “Cold-Active Alkaline Phosphatase Is Irreversibly Transformed into an Inactive Dimer by Low Urea Concentrations.”
426:
Amoutzias, Grigoris D.; Robertson, David L.; Van de Peer, Yves; Oliver, Stephen G. (2008-05-01). "Choose your partners: dimerization in eukaryotic transcription factors".
293:
alkaline phosphatase allows cooperative interactions between the constituent mutant monomers that can generate a more functional form of the
177:
471:"Major Phytocannabinoids and Their Related Compounds: Should We Only Search for Drugs That Act on Cannabinoid Receptors?"
84:
30:
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Herscovitch M, Comb W, Ennis T, Coleman K, Yong S, Armstead B, Kalaitzidis D, Chandani S, Gilmore TD (February 2008).
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Some proteins contain specialized domains to ensure dimerization (dimerization domains) and specificity.
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have the ability to form both homo- and heterodimers with several types of receptors such as
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578:, vol. 1864, no. 7, 2016, pp. 755–765, https://doi.org/10.1016/j.bbapap.2016.03.016.
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505:
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379:"Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347"
297:. The dimer has two active sites, each containing two zinc ions and a magnesium ion.
106:
56:
562:
G protein coupled receptors modeling, activation, interactions and virtual screening
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40:
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27:
Macromolecular complex formed by two, usually non-covalently bound, macromolecules
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formed by two protein monomers, or single proteins, which are usually
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Biochimica et
Biophysica Acta (BBA) - Proteins and Proteomics
109:. An example of a non-covalent heterodimer is the enzyme
105:
Most protein dimers in biochemistry are not connected by
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117:chains. An exception is dimers that are linked by
8:
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113:, which is composed of two different
102:is formed by two different proteins.
7:
25:
590:
121:such as the homodimeric protein
83:. A protein dimer is a type of
71:has roots meaning "two parts",
47:is a macromolecular complex or
428:Trends in Biochemical Sciences
178:Variable surface glycoproteins
1:
488:10.3390/pharmaceutics13111823
530:Journal of Molecular Biology
284:. That is, when particular
85:protein quaternary structure
571:. Springer New York, 2012.
567:7. Matthews, Jacqueline M.
564:(1st ed.). Academic Press.
280:, a dimer enzyme, exhibits
251:Type II restriction enzymes
94:is formed by two identical
639:
440:10.1016/j.tibs.2008.02.002
395:10.1016/j.bbrc.2007.12.123
282:intragenic complementation
238:Receptor tyrosine kinases
256:Triosephosphateisomerase
67:, form dimers. The word
542:10.1006/jmbi.2000.4230
36:
262:Alcohol dehydrogenase
160:Transcription factors
136:cannabinoid receptors
111:reverse transcriptase
33:
278:alkaline phosphatase
270:Alkaline phosphatase
53:non-covalently bound
618:Dimers (chemistry)
233:Toll-like receptor
37:
623:Protein complexes
613:Protein structure
560:6. Conn. (2013).
356:10.1021/jm0604575
307:Dimer (chemistry)
222:Nuclear receptors
133:G protein-coupled
119:disulfide bridges
16:(Redirected from
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229:βγ-subunit dimer
194:clotting factors
98:while a protein
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350:(16): 4834–41.
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173:14-3-3 proteins
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536:(4): 645–656.
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434:(5): 220–229.
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312:Protein trimer
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167:motif proteins
165:Leucine zipper
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107:covalent bonds
57:macromolecules
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475:Pharmaceutics
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65:nucleic acids
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45:protein dimer
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35:respectively.
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481:(11): 1823.
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389:(1): 103–8.
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344:J. Med. Chem
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148:adenosine A2
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41:biochemistry
38:
204:Factor XIII
182:Trypanosoma
150:receptors.
100:heterodimer
607:Categories
328:References
295:holoenzyme
209:Fibrinogen
115:amino acid
90:A protein
59:, such as
18:Homodimers
497:1999-4923
448:0968-0004
227:G protein
217:receptors
199:Factor XI
140:mu-opioid
92:homodimer
550:11099386
515:34834237
456:18406148
413:18164680
364:16884295
317:Oligomer
301:See also
184:parasite
154:Examples
144:dopamine
96:proteins
61:proteins
49:multimer
597:Biology
506:8625816
404:2277332
322:ProtCID
291:E. coli
275:E. coli
246:enzymes
188:Tubulin
180:of the
55:. Many
583:Portal
548:
513:
503:
495:
454:
446:
411:
401:
362:
286:mutant
258:(TIM)
244:Some
215:Some
192:Some
69:dimer
546:PMID
511:PMID
493:ISSN
452:PMID
444:ISSN
409:PMID
360:PMID
146:and
131:The
123:NEMO
80:-mer
43:, a
538:doi
534:304
501:PMC
483:doi
436:doi
399:PMC
391:doi
387:367
352:doi
74:di-
63:or
39:In
609::
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87:.
77:+
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20:)
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