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Hydrocephalus

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632:, are common among those with hydrocephalus, who tend to score better on verbal IQ than on performance IQ, which is thought to reflect the distribution of nerve damage to the brain. Hydrocephalus that is present from birth can cause long-term complications with speech and language. Children can have issues such as nonverbal learning disorder, difficulty understanding complex and abstract concepts, difficulty retrieving stored information, and spatial/perceptual disorders. Children with hydrocephalus are often known in having the difficulty in understanding the concepts within conversation and tend to use words they know or have heard. However, the severity of hydrocephalus can differ considerably between individuals, and some are of average or above-average intelligence. Someone with hydrocephalus may have coordination and visual problems, or clumsiness. They may reach puberty earlier than the average child (this is called 1044: 1135: 983:(NPH) is a particular form of chronic communicating hydrocephalus, characterized by enlarged cerebral ventricles, with only intermittently elevated cerebrospinal fluid pressure. Characteristic triad of symptoms are; dementia, apraxic gait and urinary incontinence. The diagnosis of NPH can be established only with the help of continuous intraventricular pressure recordings (over 24 hours or even longer), since more often than not instant measurements yield normal pressure values. Dynamic compliance studies may be also helpful. Altered compliance ( 1452: 892: 1329: 1383: 478:. With increased levels of CSF, there have been cases of hearing loss due to CSF creating pressure on the auditory pathways or disrupting the communication of inner ear fluid. Elevated ICP of different etiologies have been linked to sensorineural hearing loss (SNHL). Transient SNHL has been reported after the loss of CSF with shunt surgeries. Hearing loss is a rare but well-known sequela of procedures resulting in CSF loss. Elevated ICP may result in 662: 968: 888:, and is the site of CSF reabsorption back into the venous system. Various neurologic conditions may result in communicating hydrocephalus, including subarachnoid/intraventricular hemorrhage, meningitis, and congenital absence of arachnoid villi. Scarring and fibrosis of the subarachnoid space following infectious, inflammatory, or hemorrhagic events can also prevent reabsorption of CSF, causing diffuse ventricular dilatation. 1027: 423: 431: 1073:. These signs occur sooner in adults, whose skulls are no longer able to expand to accommodate the increasing fluid volume within. Fetuses, infants, and young children with hydrocephalus typically have an abnormally large head, excluding the face, because the pressure of the fluid causes the individual skull bones—which have yet to fuse—to bulge outward at their 1300:
transmitted. Therefore, the reduced CSF pressure could cause a decrease in Perilymphatic pressure and cause secondary endolymphatic hydrops. In addition to the increased hearing loss, there have also been findings of resolved hearing loss after ventriculoperitoneal shunt placement, where there is a release of CSF pressure on the auditory pathways.
1207:, thereby shortcutting any obstruction, as in aqueductal stenosis. This may or may not be appropriate based on individual anatomy. For infants, ETV is sometimes combined with choroid plexus cauterization, which reduces the amount of cerebrospinal fluid produced by the brain. The technique, known as ETV/CPC, was pioneered in 679:. The most common cause of congenital hydrocephalus is aqueductal stenosis, which occurs when the narrow passage between the third and fourth ventricles in the brain is blocked or too narrow to allow sufficient cerebral spinal fluid to drain. Fluid accumulates in the upper ventricles, causing hydrocephalus. 1482:
One case of hydrocephalus was a man whose brain shrank to a thin sheet of tissue, due to a buildup of cerebrospinal fluid in his skull. As a child, the man had a shunt, but it was removed when he was 14. In July 2007, at age 44, he went to a hospital due to mild weakness in his left leg. When doctors
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The person was a married father of two children, and worked as a civil servant, leading an at least superficially normal life, despite having enlarged ventricles with a decreased volume of brain tissue. "What I find amazing to this day is how the brain can deal with something which you think should
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The skull of a newborn baby is often full of liquid, either because the matron has compressed it excessively or for other, unknown reasons. The volume of the skull then increases daily, so that the bones of the skull fail to close. In this case, we must open the middle of the skull in three places,
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Following placement of a ventriculoperitoneal shunt there have been cases of a decrease in post-surgery hearing. It is presumed that the cochlea aqueduct is responsible for the decrease in hearing thresholds. The cochlea aqueduct has been considered as a probable channel where CSF pressure can be
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The elevated ICP may cause compression of the brain, leading to brain damage and other complications. A complication often overlooked is the possibility of hearing loss due to ICP. The mechanism of ICP on hearing loss is presumed that the transmission of CSF pressure to and from the Perilymphatic
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The diagnosis of CSF buildup is complex and requires specialist expertise. Diagnosis of the particular complication usually depends on when the symptoms appear, that is, whether symptoms occur when the person is upright or in a prone position, with the head at roughly the same level as the feet.
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Examples of possible complications include shunt malfunction, shunt failure, and shunt infection, along with infection of the shunt tract following surgery (the most common reason for shunt failure is infection of the shunt tract). Although a shunt generally works well, it may stop working if it
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CSF can accumulate within the ventricles, this condition is called internal hydrocephalus and may result in increased CSF pressure. The production of CSF continues, even when the passages that normally allow it to exit the brain are blocked. Consequently, fluid builds inside the brain, causing
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while North America has the fewest number of cases. A systematic review in 2019 estimated that there are 180,000 childhood hydrocephalus cases from the African continent per year, followed by 90,000 cases from Southeast Asia and the Western Pacific. Latin America also has a high prevalence of
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space through a patent cochlear aqueduct. The cochlear aqueduct connects the Perilymphatic space of the inner ear with the subarachnoid space of the posterior cranial fossa. A loss of CSF pressure can induce Perilymphatic loss or endolymphatic hydrops resembling the clinical presentation of
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may or may not show any change in ventricle size, particularly if the person has a history of slit-like ventricles. Difficulty in diagnosing over-drainage can make treatment of this complication particularly frustrating for people and their families. Resistance to traditional
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fuse by the end of the third year of life. For head enlargement to occur, hydrocephalus must occur before then. The causes are usually genetic, but can also be acquired and usually occur within the first few months of life, which include intraventricular matrix hemorrhages in
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and is continuously drained away into the circulatory system. Alternatively, the condition may result from an overproduction of the CSF, from a congenital malformation blocking normal drainage of the fluid, or from complications of head injuries or infections.
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Communicating hydrocephalus, also known as nonobstructive hydrocephalus, is caused by impaired CSF reabsorption in the absence of any obstruction of CSF flow between the ventricles and subarachnoid space. This may be due to functional impairment of the
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is more likely to manifest with the nonspecific signs and symptoms of increased intracranial pressure (ICP). By contrast, chronic dilatation (especially in the elderly population) may have a more insidious onset presenting, for instance, with
4006: 3987: 1252:. The shunt failure rate is also relatively high (of the 40,000 surgeries performed annually to treat hydrocephalus, only 30% are a person's first surgery) and people not uncommonly have multiple shunt revisions within their lifetimes. 1470:. The resolution campaign is due in part to the advocacy work of the Pediatric Hydrocephalus Foundation. Prior to July 2009, no awareness month for this condition had been designated. Many hydrocephalus organizations, such as the 5063: 1052:
Hydrocephalus is usually due to blockage of CSF outflow in the ventricles or in the subarachnoid space over the brain. In a person without hydrocephalus, CSF continuously circulates through the brain, its ventricles and the
1158:) into the cerebral ventricles to bypass the flow obstruction/malfunctioning arachnoidal granulations and drain the excess fluid into other body cavities, from where it can be resorbed. Most shunts drain the fluid into the 3332:
Yang MM, Hader W, Bullivant K, Brindle M, Riva-Cambrin J (February 2019). "Calgary Shunt Protocol, an adaptation of the Hydrocephalus Clinical Research Network shunt protocol, reduces shunt infections in children".
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learned of the man's medical history, they performed a CT and MRI scan, and were astonished to see "massive enlargement" of the lateral ventricles in the skull. Dr. Lionel Feuillet of Hôpital de la Timone in
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Nimjee SM, Powers CJ, McLendon RE, Grant GA, Fuchs HE (April 2010). "Single-stage bilateral choroid plexectomy for choroid plexus papilloma in a patient presenting with high cerebrospinal fluid output".
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sets in, and infants show lack of interest in their surroundings. Later on, their upper eyelids become retracted and their eyes are turned downwards ("sunset eyes") (due to hydrocephalic pressure on the
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Riveros Gilardi B, Muñoz López JI, Hernández Villegas AC, Garay Mora JA, Rico Rodríguez OC, Chávez Appendini R, et al. (October 2019). "Types of Cerebral Herniation and Their Imaging Features".
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Standardized protocols for inserting cerebral shunts have been shown to reduce shunt infections. There is tentative evidence that preventative antibiotics may decrease the risk of shunt infections.
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disconnects, becomes blocked (clogged) or infected, or it is outgrown. If this happens, the CSF begins to accumulate again and a number of physical symptoms develop (headaches, nausea, vomiting,
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and is now in use in several U.S. hospitals. Hydrocephalus can be successfully treated by placing a drainage tube (shunt) between the brain ventricles and abdominal cavity. Some risk exists of
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In newborns and toddlers with hydrocephalus, the head circumference is enlarged rapidly and soon surpasses the 97th percentile. Since the skull bones have not yet firmly joined, bulging, firm
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Lim HW, Shim BS, Yang CJ, Kim JH, Cho YH, Cho YS, et al. (August 2014). "Hearing loss following ventriculoperitoneal shunt in communicating hydrocephalus patients: a pilot study".
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External hydrocephalus is a condition generally seen in infants which involves enlarged fluid spaces or subarachnoid spaces around the outside of the brain. This condition is generally
3051: 375:, or obstruction. This may require replacement. Outcomes are variable, but many people with shunts live normal lives. Without treatment, permanent disability or death may occur. 2938: 1398:
pioneered sterile ventricular puncture and external drainage of CSF for the treatment of hydrocephalus. It remained an intractable condition until the 20th century, when
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The cause of hydrocephalus is not known with certainty and is probably multifactorial. It may be caused by impaired CSF flow, reabsorption, or excessive CSF production.
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Sammons VJ, Jacobson E, Lawson J (October 2009). "Resolution of hydrocephalus-associated sensorineural hearing loss after insertion of ventriculoperitoneal shunt".
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may be higher. Normal pressure hydrocephalus is estimated to affect about 5 per 100,000 people, with rates increasing with age. Description of hydrocephalus by
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Gavrilov, Gaspar V.; Gaydar, Boris V.; Svistov, Dmitry V.; Korovin, Alexander E.; Samarcev, Igor N.; Churilov, Leonid P.; Tovpeko, Dmitry V. (December 2019).
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Cinalli, G.; Sainte-Rose, C.; Kollar, E. M.; Zerah, M.; Brunelle, F.; Chumas, P.; Arnaud, E.; Marchac, D.; Pierre-Kahn, A.; Renier, D. (February 1998).
2700: 1632: 4959: 3201:"Delayed diagnosis of shunt overdrainage following functional hemispherotomy and ventriculoperitoneal shunt placement in a hemimegalencephaly patient" 1496: 1340:(large head) or clinical findings of hydrocephalus. The earliest scientific description of hydrocephalus was written by the ancient Greek physician 1146:(EVD), also known as an extraventricular drain or ventriculostomy, provides relief. In the long term, some people will need any of various types of 3378:"A standardized protocol to reduce cerebrospinal fluid shunt infection: the Hydrocephalus Clinical Research Network Quality Improvement Initiative" 5255: 4949: 4126: 1043: 707:, infections, type II Arnold-Chiari malformation, aqueduct atresia and stenosis, and Dandy-Walker malformation. Hydrocephalus can also occur with 264:
Varies throughout the world, from 1 per 256 live births to 1 per 9,000, depending on access to prenatal health care, prenatal tests, and abortion
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Peltopuro M, Ahonen T, Kaartinen J, Seppälä H, Närhi V (December 2014). "Borderline intellectual functioning: a systematic literature review".
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said, "The images were most unusual... the brain was virtually absent." Intelligence tests showed the person had an IQ of 75, considered "
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Hydrocephalus can be classified into communicating and noncommunicating (obstructive). Both forms can be either congenital or acquired.
5011: 4944: 4499: 2564:"The influence of coughing on cerebrospinal fluid pressure in an in vitro syringomyelia model with spinal subarachnoid space stenosis" 1528: 2043:
Barnes MA, Dennis M (February 1998). "Discourse after early-onset hydrocephalus: core deficits in children of average intelligence".
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Marchbanks RJ, Reid A (June 1990). "Cochlear and cerebrospinal fluid pressure: their inter-relationship and control mechanisms".
1200: 3655: 5207: 4833: 3797: 2336: 1369:, who described the evacuation of superficial intracranial fluid in hydrocephalic children. He described it in his chapter on 695: 4348: 4324: 4154: 4540: 955: 3139:
Ravid, Sarit; Maytal, Joseph (February 2003). "External hydrocephalus: a probable cause for subdural hematoma in infancy".
5027: 4912: 4828: 4770: 4319: 3955: 3631: 3285:"Continuous, noninvasive wireless monitoring of flow of cerebrospinal fluid through shunts in patients with hydrocephalus" 1443:
meaning 'head'. Other names for hydrocephalus include "water on the brain", a historical name, and "water baby syndrome".
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A shunt system can also be placed in the lumbar space of the spine and have the CSF redirected to the peritoneal cavity (
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Dewan MC, Rattani A, Mekary R, Glancz LJ, Yunusa I, Baticulon RE, Fieggen G, Wellons JC, Park KB, Warf BC (April 2018).
754:. Papilledema is absent, but vision may be reduced. The head becomes so enlarged that they eventually may be bedridden. 3819: 3674: 3067:"Neurosurgery for Hydrocephalus Treatment & Management: Approach Considerations, Medical Therapy, Surgical Therapy" 1203:(ETV), whereby a surgically created opening in the floor of the third ventricle allows the CSF to flow directly to the 5359: 5230: 4506: 1035: 341: 223: 3577:
Aschoff A, Kremer P, Hashemi B, Kunze S (October 1999). "The scientific history of hydrocephalus and its treatment".
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is an option in some people. Complications from shunts may include overdrainage, underdrainage, mechanical failure,
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or symptomatic chronic extra-axial fluid collections which are accompanied by vomiting, headaches, and seizures.
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Oi S (1999), "Hydrocephalus Associated with Spina Bifida: Specific Pathophysiology and Therapeutic Problems",
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Dixon JF, Jones RO (June 2012). "Hydrocephalus-associated hearing loss and resolution after ventriculostomy".
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Hydrocephalus treatment is surgical, creating a way for the excess fluid to drain away. In the short term, an
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Noncommunicating hydrocephalus, or obstructive hydrocephalus, is caused by an obstruction to the flow of CSF.
1853:"Idiopathic Normal Pressure Hydrocephalus (Hakim-Adams Syndrome): Clinical Symptoms, Diagnosis and Treatment" 4939: 4695: 4513: 4365: 4355: 4199: 3892: 2708: 2537: 1888:
Satzer D, Guillaume DJ (January 2016). "Hearing loss in hydrocephalus: a review, with focus on mechanisms".
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Congenital hydrocephalus is present in the infant prior to birth, meaning the fetus developed hydrocephalus
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also refers to an enlargement of cerebral ventricles and subarachnoid spaces, and is usually due to brain
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to appear when the person is vertical. If the person lies down, the symptoms usually vanish quickly. A
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The infant exhibits fretfulness, poor feeding, and frequent vomiting. As the hydrocephalus progresses,
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Kestle JR, Riva-Cambrin J, Wellons JC, Kulkarni AV, Whitehead WE, Walker ML, et al. (July 2011).
2310: 1542:(1793–1875) became emperor in 1835 despite various health issues including hydrocephalus and epilepsy. 1336:
In the pre-historic area, there were various paintings or artifacts depicting children or adults with
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Compression of the brain by the accumulating fluid eventually may cause neurological symptoms such as
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being introduced into the brain through these shunts, as they must be replaced as the person grows.
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obstruction leads to dilatation of the aqueduct, as well as the lateral and third ventricles (e.g.,
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not be compatible with life", commented Dr. Max Muenke, a pediatric brain-defect specialist at the
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disease, describing infantile hydrocephalus as being caused by mechanical compression. He wrote:
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Du Plessis, Adré J.; Robinson, Shenandoah; Volpe, Joseph J. (2018). "Congenital Hydrocephalus".
1259:, causing symptoms of listlessness, severe headaches, irritability, light sensitivity, auditory 925:, normally narrow, may be obstructed by a number of genetic or acquired lesions (e.g., atresia, 3918: 536:(soft spot) to bulge and the head to be larger than expected. Early symptoms may also include: 525:
are located). The symptoms depend on the cause of the blockage, the person's age, and how much
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In infants with hydrocephalus, CSF builds up in the central nervous system (CNS), causing the
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Because hydrocephalus can injure the brain, thought and behavior may be adversely affected.
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is a relatively typical manifestation of the distinct entity normal-pressure hydrocephalus.
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Kahle KT, Kulkarni AV, Limbrick DD, Warf BC (February 2016). "Hydrocephalus in children".
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The first clinical description of an operative procedure for hydrocephalus appears in the
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Nagahama Y, Peters D, Kumonda S, Vesole A, Joshi C, J Dlouhy B, Kawasaki H (2017-01-24).
2742:"Hearing loss and cerebrospinal fluid pressure: case report and review of the literature" 2362:"Acquired Hydrocephalus | Conditions & Treatments | UCSF Benioff Children's Hospital" 2110: 301:. In babies, it may be seen as a rapid increase in head size. Other symptoms may include 2740:
Pogodzinski MS, Shallop JK, Sprung J, Weingarten TN, Wong GY, McDonald TJ (March 2008).
929:, hemorrhage, or tumor) and lead to dilation of both lateral ventricles, as well as the 848:
Hydrocephalus can also be caused by overproduction of CSF (relative obstruction) (e.g.,
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This article is about the medical condition. For the creature in American folklore, see
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Another complication can occur when CSF drains more rapidly than it is produced by the
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Burton A (August 2015). "Infant hydrocephalus in Africa: spreading some good news".
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September was designated National Hydrocephalus Awareness Month in July 2009 by the
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make the liquid flow out, then close the wound and tighten the skull with a bandage.
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hydrocephalus. However, data on hydrocephalus disease burden in adults are lacking.
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when the hydrocephalus occurs, the pressure may also severely enlarge the head. The
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Obstruction to CSF flow hinders its free passage through the ventricular system and
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Krishnan SR, Arafa HM, Kwon K, Deng Y, Su CJ, Reeder JT, et al. (2020-03-06).
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Nagra, Gurjit; Del Bigio, Marc R. (2018). "Pathology of Pediatric Hydrocephalus".
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A one-year-old girl with hydrocephalus showing "sunset eyes", before shunt surgery
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Feuillet L, Dufour H, Pelletier J (July 2007). "Brain of a white-collar worker".
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Fetal and Neonatal Brain Injury: Mechanisms, Management and the Risks of Practice
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Nouwens PJ, Lucas R, Smulders NB, Embregts PJ, van Nieuwenhuizen C (July 2017).
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Illustration showing different effects of hydrocephalus on the brain and cranium
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Historical specimen of an infant with severe hydrocephalus, probably untreated
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Otology, Neurotology, and Lateral Skull Base Surgery: An Illustrated Handbook
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pharmacological therapy may also be a sign of shunt overdrainage or failure.
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Yadav YR, Mukerji G, Shenoy R, Basoor A, Jain G, Nelson A (January 2007).
2278: 2247: 2064: 1994: 1563:, a professional soccer player, died of hydrocephalus on October 21, 2022. 4669: 4661: 4627: 4481: 4384: 1284: 1276: 1155: 1151: 1106: 1002: 818: 637: 569:
Changes in facial appearance and eye spacing (craniofacial disproportion)
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Nelson SL, Murro AM, Espay AJ, Hord ED (2022-03-11). Talavera F (ed.).
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Further information on the non-invasive diagnostic medical device:
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Abnormal increase in cerebrospinal fluid in the ventricles of the brain
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or may become blocked later in life because of a tumor growing in the
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obstruction may lead to dilation of one, or if large enough (e.g., in
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Engelhard III HH, Sahrakar K, Pang D (2022-03-03). Talavera F (ed.).
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of Ohio, Michigan, and Connecticut, an urban legend exists about the
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About one to two per 1,000 newborns have hydrocephalus. Rates in the
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Spinal muscular atrophy with lower extremity predominance (SMALED)
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Hydrocephalus is typically treated by the surgical placement of a
278: 2387:"Hydrocephalus: Practice Essentials, Background, Pathophysiology" 566:
Changes in personality, memory, or the ability to reason or think
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Nelson Jr SL, Espay AJ, Hord ED (2022-02-02). Talavera F (ed.).
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of the cerebrospinal fluid, may play a role in the pathogenesis.
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of upward gaze). Movements become weak and the arms may become
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may be present even when the person is in an upright position.
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or be acquired later in life. Associated birth defects include
73:
of the brain. The black areas in the middle of the brain (the
2538:"Communicating and Non-communicating Hydrocephalus | Helpful" 1402:
and other neurosurgical treatment modalities were developed.
3893:"Oilers forward Colby Cave dies after suffering brain bleed" 3004:"Hydrocephalus and shunts: what the neurologist should know" 2134: 863:
obstruction is a rare, but reported, cause of hydrocephalus.
801:(subarachnoid or intraparenchymal), and is usually painful. 434:
Adult showing cranial deformity from pediatric hydrocephalus
1438: 1426: 409: 397: 133: 127: 121: 112: 103: 2263:"Congenital syphilis: A guide to diagnosis and management" 1512:
had acute obstructive hydrocephalus due to a colloid cyst.
356:. Diagnosis is typically made by physical examination and 2024:
Kaneshiro NK, Zieve D, Black B, A.D.A.M. Editorial team.
1315:
The hydrocephalus disease burden are concentrated in the
1093:
pressure that dilates the ventricles and compresses the
954:
may be obstructed due to congenital malformation (e.g.,
2705:
National Institute of Neurological Disorders and Stroke
1097:. Compression of the nervous tissue usually results in 559:
Symptoms that may occur in older children can include:
438:
The clinical presentation of hydrocephalus varies with
3531:. Cham: Springer International Publishing. p. 3. 3790:"Man Lives Normal Life Despite Having Abnormal Brain" 3525:"History of Hydrocephalus and Its Surgical Treatment" 1263:(sound sensitivity), hearing loss, nausea, vomiting, 1248:/light sensitivity), some extremely serious, such as 1017:
loss; it is not the result of increased CSF pressure.
136: 124: 118: 97: 3969: 130: 109: 106: 5302: 5279: 5270: 5147: 5099: 5090: 4885: 4862: 4853: 4846: 4801: 4751: 4723: 4694: 4660: 4622: 4611: 4577: 4555: 4480: 4290: 4281: 4267: 4227: 4170: 4161: 4070: 3973: 3425:Arts SH, Boogaarts HD, van Lindert EJ (June 2019). 1432: 1420: 777:This condition is acquired as a consequence of CNS 403: 391: 260: 250: 242: 229: 203: 163: 151: 115: 100: 85: 51: 46: 3008:Journal of Neurology, Neurosurgery, and Psychiatry 1009:, and even in some psychiatric disorders, such as 3050:: CS1 maint: DOI inactive as of September 2024 ( 2865:"Hydrocephalus: Causes, symptoms, and treatments" 1390:In 1881, a few years after the landmark study of 987:) of the ventricular walls, as well as increased 715:and frequently seen in syndomic cases (mostly in 682:Other causes of congenital hydrocephalus include 3623:Death, Modernity, and the Body: Sweden 1870-1940 1474:, promote awareness and fundraising activities. 1089:associated hearing loss in the low frequencies. 757:About 80–90% of fetuses or newborn infants with 719:). Hydrocephalus has also been seen in cases of 1766:Ellenbogen RG, Abdulrauf SI, Sekhar LN (2012). 1522:The Absolutely True Diary of a Part-Time Indian 1375: 895:An adult with congenital hydrocephalus in the 3656:"Man with Almost No Brain Has Led Normal Life" 1048:3D cast of lateral ventricles in hydrocephalus 845:malformations) and can cause increases in ICP. 665:Hydrocephalus in a child with kleeblattschadel 5064: 4134: 1150:. It involves the placement of a ventricular 8: 521:, where the neural centers coordinating the 3705:Intellectual and Developmental Disabilities 3431:The Cochrane Database of Systematic Reviews 1796:Ferri's Clinical Advisor 2017: 5 Books in 1 1535:at birth, which resulted in this condition. 386:dates back more than 2,000 years. The word 273:is a condition in which an accumulation of 5276: 5096: 5071: 5057: 5049: 4859: 4850: 4619: 4287: 4278: 4167: 4141: 4127: 4119: 3970: 3572: 3570: 3568: 3566: 3564: 2526:. Cambridge University Press. p. 106. 2261:Arnold SR, Ford-Jones EL (November 2000). 1677: 1675: 1619: 1617: 1615: 1613: 1611: 1609: 1607: 1605: 1603: 1601: 1599: 1597: 572:Crossed eyes or uncontrolled eye movements 60: 43: 3765: 3755: 3491: 3450: 3401: 3308: 3224: 3027: 2906: 2757: 2676: 2666: 2589: 2579: 2311:"What You Should Know About Macrocephaly" 2286: 1830:(29th ed.). W.B. Saunders Co. 2000. 1822: 1820: 1799:. Elsevier Health Sciences. p. 621. 1772:. Elsevier Health Sciences. p. 105. 1595: 1593: 1591: 1589: 1587: 1585: 1583: 1581: 1579: 1577: 1761: 1759: 1497:National Human Genome Research Institute 1450: 890: 594:Loss of coordination and trouble walking 421: 5256:Bilateral frontoparietal polymicrogyria 2423:Adunka O, Buchman C (11 October 2010). 1828:Dorland's electronic medical dictionary 1573: 880:(also called arachnoid granulations or 5345:Congenital disorders of nervous system 4930:Distal hereditary motor neuronopathies 4603:Template:Demyelinating diseases of CNS 3965:Guidelines for pediatric hydrocephalus 3658:. Fox News. 2007-07-25. Archived from 3043: 2524:Essentials of Pediatric Anesthesiology 1332:Skull of a hydrocephalic child (1800s) 454:Symptoms of increased ICP may include 2889:Yadav YR, Parihar V, Sinha M (2010). 2816: 2814: 2812: 2735: 2733: 2611: 2609: 2339:. Spinabifidamoms.com. Archived from 1976: 1974: 1972: 1970: 1275:, seizures, a change in personality, 1166:), but alternative sites include the 975:from vascular dementia as seen on MRI 7: 4781:Idiopathic intracranial hypertension 3820:"Man with tiny brain shocks doctors" 3667:"Man with tiny brain shocks doctors" 3205:Epilepsy & Behavior Case Reports 2216:"Hydrocephalus and craniosynostosis" 2090:, Springer Japan, pp. 177–184, 1933:Otolaryngology–Head and Neck Surgery 1883: 1881: 3382:Journal of Neurosurgery. Pediatrics 3335:Journal of Neurosurgery. Pediatrics 3250:Journal of Neurosurgery. Pediatrics 2562:Martin BA, Loth F (December 2009). 2465:Journal of Neurosurgery. Pediatrics 1489:Borderline intellectual functioning 1038:with hydrocephalus shown on CT scan 5082:malformations and deformations of 5012:Infantile progressive bulbar palsy 3176:"Pharmacology of Shunt Infections" 2499:"Different Types of Hydrocephalus" 2191:10.1016/B978-0-323-42876-7.00003-X 1769:Principles of Neurological Surgery 1529:Prince William, Duke of Gloucester 1138:Baby recovering from shunt surgery 529:has been damaged by the swelling. 482:, with resulting life-threatening 281:. This typically causes increased 14: 4715:Template:Cerebrovascular diseases 4518:Frontotemporal lobar degeneration 3830:from the original on 26 July 2013 1635:from the original on 27 July 2016 1531:(1689–1700), probably contracted 584:Irritability, poor temper control 540:Eyes that appear to gaze downward 4735:For more detailed coverage, see 4713:For more detailed coverage, see 4684:For more detailed coverage, see 4650:For more detailed coverage, see 4601:For more detailed coverage, see 3104:from the original on 2023-07-08. 2618:Complications in neuroanesthesia 2503:Advanced Neurosurgery Associates 2443:from the original on 5 July 2014 2183:Volpe's Neurology of the Newborn 1813:from the original on 2016-12-21. 1709:from the original on 2016-12-21. 1201:endoscopic third ventriculostomy 523:conjugated vertical eye movement 93: 5208:Agenesis of the corpus callosum 3925:from the original on 2013-05-20 3796:. July 19, 2007. Archived from 3585:(2–3): 67–93, discussion 94–5. 3174:Benner KW, Spellen S, Jeske A. 2941:from the original on 2016-03-02 2746:Ear, Nose, & Throat Journal 2131:"The Hydrocephalus Association" 884:), which are located along the 563:Brief, shrill, high-pitched cry 316:Hydrocephalus can occur due to 3443:10.1002/14651858.CD012902.pub2 2522:Kaye A, Fox C, Diaz J (2014). 2267:Paediatrics & Child Health 2158:10.1007/978-3-319-31889-9_43-1 1113:may be blocked at the time of 711:, being a constant feature of 636:). About one in four develops 1: 5028:Amyotrophic lateral sclerosis 4913:Hereditary spastic paraplegia 4771:Normal pressure hydrocephalus 3863:10.1016/S0140-6736(07)61127-1 3632:University of Rochester Press 3153:10.1016/s0887-8994(02)00500-3 2973:10.1016/S1474-4422(15)00138-6 2707:. August 2005. Archived from 1734:10.1016/s0140-6736(15)60694-8 981:Normal pressure hydrocephalus 604:Slow growth (child 0–5 years) 480:uncal or tonsillar herniation 311:downward pointing of the eyes 4997:Progressive muscular atrophy 3688:. 2007-07-24. Archived from 3673:. 2007-07-20. Archived from 2783:British Journal of Audiology 2568:Cerebrospinal Fluid Research 2366:www.ucsfbenioffchildrens.org 1439: 1427: 410: 398: 222:, brain bleed during birth, 5174:other reduction deformities 4507:Primary progressive aphasia 3084:Greenberg MS (2010-02-15). 3020:10.1136/jnnp.73.suppl_1.i17 3002:Pople IK (September 2002). 1896:(1): 13–24, discussion 25. 1036:intraventricular hemorrhage 918:), both lateral ventricles. 617:Slow or restricted movement 503:Focal neurological deficits 342:intraventricular hemorrhage 256:Variable, often normal life 224:intraventricular hemorrhage 69:Hydrocephalus as seen on a 5376: 5350:Disorders causing seizures 4829:Hashimoto's encephalopathy 4535:Posterior cortical atrophy 4356:Striatonigral degeneration 4207:Cavernous sinus thrombosis 3717:10.1352/1934-9556-52.6.419 3217:10.1016/j.ebcr.2016.12.003 2935:Public Radio International 2759:10.1177/014556130808700308 2701:"Hydrocephalus Fact Sheet" 2232:10.3171/jns.1998.88.2.0209 1693:Cambridge University Press 1625:"Hydrocephalus Fact Sheet" 1472:One Small Voice Foundation 1433: 1421: 1352:in the second century AD. 1188: 1164:ventriculoperitoneal shunt 1144:external ventricular drain 696:Arnold–Chiari malformation 517:due to compression of the 442:. Acute dilatation of the 404: 392: 297:, personality changes, or 29: 18: 4935:Spinal muscular atrophies 4903:Primary lateral sclerosis 4761:Intracranial hypertension 4541:Creutzfeldt–Jakob disease 3824:New Scientist and Reuters 3757:10.1186/s12888-017-1426-8 3682:"Tiny Brain, Normal Life" 3537:10.1007/978-3-319-27250-4 3347:10.3171/2018.10.PEDS18420 3301:10.1038/s41746-020-0239-1 2891:"Lumbar peritoneal shunt" 2795:10.3109/03005369009076554 2616:Hemanshu P (2016-02-29). 2477:10.3171/2009.10.peds08454 2429:. Thieme. pp. 353–. 1902:10.1007/s10143-015-0650-2 1105:bones are not completely 1099:irreversible brain damage 956:Dandy–Walker malformation 827:interventricular foramina 587:Loss of bladder control ( 324:and those that result in 283:pressure inside the skull 68: 59: 36:Hydrocephalus (trilobite) 34:. For the trilobite, see 5160:Congenital hydrocephalus 5002:Progressive bulbar palsy 4793:Intracranial hypotension 4776:Choroid plexus papilloma 4190:Herpesviral encephalitis 3493:10.3171/2017.10.JNS17439 3394:10.3171/2011.4.PEDS10551 3262:10.3171/2009.4.PEDS09103 3087:Handbook of Neurosurgery 2869:www.medicalnewstoday.com 1945:10.1177/0194599811431234 1007:traumatic brain injuries 882:Pacchioni's granulations 878:arachnoidal granulations 850:choroid plexus papilloma 769:—develop hydrocephalus. 505:may also occur, such as 285:. Older people may have 277:(CSF) occurs within the 19:Not to be confused with 4514:Frontotemporal dementia 4200:Encephalitis lethargica 3529:Pediatric Hydrocephalus 3480:Journal of Neurosurgery 3022:(inactive 2024-09-12). 2908:10.4103/0028-3886.63778 2220:Journal of Neurosurgery 2150:Pediatric Hydrocephalus 1197:lumbar-peritoneal shunt 1180:ventriculopleural shunt 1067:intellectual disability 886:superior sagittal sinus 799:intracranial hemorrhage 761:—often associated with 744:mesencephalic tegmentum 367:. A procedure called a 346:subarachnoid hemorrhage 328:. Other causes include 196:, personality changes, 4819:Hepatic encephalopathy 2581:10.1186/1743-8454-6-17 2057:10.1006/brln.1998.1843 1540:Ferdinand I of Austria 1459: 1387: 1380: 1333: 1223:External hydrocephalus 1172:ventriculoatrial shunt 1139: 1049: 1039: 995:Hydrocephalus ex vacuo 976: 899: 825:or obstruction of the 666: 658: 630:short-term memory loss 435: 427: 402:, meaning 'water' and 338:traumatic brain injury 235:Based on symptoms and 220:traumatic brain injury 81:and filled with fluid. 5213:Septo-optic dysplasia 5165:Dandy–Walker syndrome 4877:Ataxia–telangiectasia 4834:Static encephalopathy 4557:Mitochondrial disease 4395:Spasmodic torticollis 4305:Basal ganglia disease 3591:10.1007/s101430050035 2961:The Lancet. Neurology 2668:10.1186/1471-2377-7-1 1995:10.1148/rg.2019190018 1454: 1385: 1331: 1279:in the arms or legs, 1137: 1047: 1029: 970: 894: 732:posterior fontanelles 692:Dandy–Walker syndrome 664: 656: 626:Learning disabilities 433: 425: 369:third ventriculostomy 172:: rapid head growth, 4824:Toxic encephalopathy 4530:Lewy bodies dementia 3919:"Man of many tribes" 3579:Neurosurgical Review 3289:npj Digital Medicine 3180:www.uspharmacist.com 3014:(suppl 1): i17–i22. 2620:. Elsevier Science. 1890:Neurosurgical Review 1866:(Suppl 5): 737–744. 1860:Psychiatria Danubina 1685:, Benitz WE (2003). 1431:meaning 'water' and 1233:subdural hemorrhages 589:urinary incontinence 578:Excessive sleepiness 495:urinary incontinence 295:urinary incontinence 194:urinary incontinence 5139:Chiari malformation 4872:Friedreich's ataxia 4255:Meningoencephalitis 4195:Limbic encephalitis 3628:Rochester, New York 3523:Cinalli, G (2019). 3141:Pediatric Neurology 3120:www.reliasmedia.com 2279:10.1093/pch/5.8.463 1406:Society and culture 1239:Shunt complications 952:foramen of Magendie 948:foramina of Luschka 941:Chiari malformation 923:aqueduct of Sylvius 721:congenital syphilis 597:Muscle spasticity ( 519:quadrigeminal plate 509:palsy and vertical 326:aqueductal stenosis 322:neural tube defects 275:cerebrospinal fluid 208:Neural tube defects 5360:Ventricular system 5310:Currarino syndrome 5281:Neural tube defect 5223:Hemimegalencephaly 5189:Microlissencephaly 5101:Neural tube defect 4908:Pseudobulbar palsy 4646:Status epilepticus 4597:Multiple sclerosis 4434:Myoclonic epilepsy 4297:movement disorders 4243:Acute disseminated 4185:Viral encephalitis 4071:External resources 3800:on August 28, 2007 3794:The Globe and Mail 2835:10.1002/lary.24553 2724:Physical diagnosis 2542:www.hydroassoc.org 2185:. pp. 58–72. 2045:Brain and Language 1728:(10020): 788–799. 1508:Ice hockey player 1460: 1447:Awareness campaign 1419:is from the Greek 1388: 1361:(1,000 AD) by the 1334: 1140: 1071:epileptic seizures 1050: 1040: 977: 900: 815:subarachnoid space 667: 659: 634:precocious puberty 608:Delayed milestones 575:Difficulty feeding 444:ventricular system 436: 428: 418:Signs and symptoms 414:, meaning 'head'. 390:is from the Greek 75:lateral ventricles 55:Water on the brain 5332: 5331: 5328: 5327: 5266: 5265: 5179:Holoprosencephaly 5046: 5045: 5042: 5041: 5038: 5037: 4842: 4841: 4747: 4746: 4686:Template:Headache 4652:Template:Epilepsy 4573: 4572: 4547:Vascular dementia 4390:Status dystonicus 4263: 4262: 4238:Encephalomyelitis 4116: 4115: 3546:978-3-319-27248-1 2937:. 22 April 2015. 2722:Cabot RC (1919). 2436:978-3-13-149621-8 2200:978-0-323-42876-7 2167:978-3-319-31889-9 2152:. pp. 1–25. 2097:978-4-431-70260-3 1793:Ferri FF (2016). 1779:978-1-4377-0701-4 1631:. April 5, 2016. 1547:American folklore 1160:peritoneal cavity 1111:cerebral aqueduct 1087:Ménière's disease 1001:(as it occurs in 823:cerebral aqueduct 705:premature infants 677:fetal development 613:Failure to thrive 549:Separated sutures 515:Parinaud syndrome 489:Hakim's triad of 299:mental impairment 268: 267: 231:Diagnostic method 198:mental impairment 41:Medical condition 5367: 5315:Diastomatomyelia 5277: 5097: 5073: 5066: 5059: 5050: 4860: 4851: 4809:Brain herniation 4620: 4460:Intention tremor 4455:Essential tremor 4320:Postencephalitic 4288: 4279: 4168: 4149:Diseases of the 4143: 4136: 4129: 4120: 3971: 3943: 3942:Somerset, p. 116 3940: 3934: 3933: 3931: 3930: 3921:. Star Tribune. 3915: 3909: 3908: 3906: 3904: 3899:. April 11, 2020 3889: 3883: 3882: 3846: 3840: 3839: 3837: 3835: 3826:. 20 July 2007. 3816: 3810: 3809: 3807: 3805: 3786: 3780: 3779: 3769: 3759: 3735: 3729: 3728: 3700: 3694: 3693: 3678: 3663: 3652: 3646: 3645: 3620:Åhrén E (2009). 3617: 3611: 3610: 3574: 3559: 3558: 3520: 3514: 3513: 3495: 3486:(4): 1065–1079. 3471: 3465: 3464: 3454: 3422: 3416: 3415: 3405: 3373: 3367: 3366: 3329: 3323: 3322: 3312: 3280: 3274: 3273: 3245: 3239: 3238: 3228: 3196: 3190: 3189: 3187: 3186: 3171: 3165: 3164: 3136: 3130: 3129: 3127: 3126: 3112: 3106: 3105: 3081: 3075: 3074: 3062: 3056: 3055: 3049: 3041: 3031: 2999: 2993: 2992: 2956: 2950: 2949: 2947: 2946: 2927: 2921: 2920: 2910: 2886: 2880: 2879: 2877: 2876: 2861: 2855: 2854: 2829:(8): 1923–1927. 2823:The Laryngoscope 2818: 2807: 2806: 2778: 2772: 2771: 2761: 2737: 2728: 2727: 2719: 2713: 2712: 2697: 2691: 2690: 2680: 2670: 2646: 2640: 2639: 2613: 2604: 2603: 2593: 2583: 2559: 2553: 2552: 2550: 2549: 2534: 2528: 2527: 2519: 2513: 2512: 2510: 2509: 2495: 2489: 2488: 2459: 2453: 2452: 2450: 2448: 2420: 2414: 2413: 2401: 2395: 2394: 2382: 2376: 2375: 2373: 2372: 2358: 2352: 2351: 2349: 2348: 2333: 2327: 2326: 2324: 2323: 2307: 2301: 2300: 2290: 2258: 2252: 2251: 2211: 2205: 2204: 2178: 2172: 2171: 2145: 2139: 2138: 2133:. Archived from 2127: 2121: 2120: 2118: 2117: 2107: 2101: 2100: 2083: 2077: 2076: 2040: 2034: 2033: 2021: 2015: 2014: 1989:(6): 1598–1610. 1978: 1965: 1964: 1939:(6): 1037–1039. 1928: 1922: 1921: 1885: 1876: 1875: 1857: 1848: 1842: 1841: 1824: 1815: 1814: 1790: 1784: 1783: 1763: 1754: 1753: 1717: 1711: 1710: 1679: 1670: 1669: 1667: 1665: 1651: 1645: 1644: 1642: 1640: 1621: 1478:Exceptional case 1457:awareness ribbon 1442: 1436: 1435: 1430: 1424: 1423: 1317:developing world 1211:by neurosurgeon 1154:(a tube made of 1046: 937:Fourth ventricle 912:Foramen of Monro 903:Noncommunicating 767:myelomeningocele 717:Crouzon syndrome 713:kleeblattschadel 709:craniosynostosis 451:(Adams' triad). 413: 407: 406: 401: 395: 394: 380:developing world 293:, poor balance, 192:, poor balance, 143: 142: 139: 138: 135: 132: 129: 126: 123: 120: 117: 114: 111: 108: 105: 102: 99: 79:abnormally large 64: 44: 5375: 5374: 5370: 5369: 5368: 5366: 5365: 5364: 5335: 5334: 5333: 5324: 5298: 5262: 5199:Hydranencephaly 5143: 5086: 5077: 5047: 5034: 4960:Congenital DSMA 4881: 4838: 4797: 4743: 4731:Sleep disorders 4719: 4696:Cerebrovascular 4690: 4656: 4613: 4607: 4569: 4551: 4476: 4422:Choreoathetosis 4295: 4272: 4259: 4223: 4157: 4147: 4117: 4112: 4111: 4066: 4065: 3982: 3952: 3947: 3946: 3941: 3937: 3928: 3926: 3917: 3916: 3912: 3902: 3900: 3891: 3890: 3886: 3848: 3847: 3843: 3833: 3831: 3818: 3817: 3813: 3803: 3801: 3788: 3787: 3783: 3737: 3736: 3732: 3702: 3701: 3697: 3680: 3665: 3654: 3653: 3649: 3642: 3619: 3618: 3614: 3576: 3575: 3562: 3547: 3522: 3521: 3517: 3473: 3472: 3468: 3437:(6): CD012902. 3424: 3423: 3419: 3375: 3374: 3370: 3331: 3330: 3326: 3282: 3281: 3277: 3247: 3246: 3242: 3198: 3197: 3193: 3184: 3182: 3173: 3172: 3168: 3138: 3137: 3133: 3124: 3122: 3114: 3113: 3109: 3098: 3083: 3082: 3078: 3064: 3063: 3059: 3042: 3001: 3000: 2996: 2958: 2957: 2953: 2944: 2942: 2929: 2928: 2924: 2895:Neurology India 2888: 2887: 2883: 2874: 2872: 2863: 2862: 2858: 2820: 2819: 2810: 2780: 2779: 2775: 2739: 2738: 2731: 2721: 2720: 2716: 2699: 2698: 2694: 2648: 2647: 2643: 2628: 2615: 2614: 2607: 2561: 2560: 2556: 2547: 2545: 2536: 2535: 2531: 2521: 2520: 2516: 2507: 2505: 2497: 2496: 2492: 2461: 2460: 2456: 2446: 2444: 2437: 2422: 2421: 2417: 2403: 2402: 2398: 2384: 2383: 2379: 2370: 2368: 2360: 2359: 2355: 2346: 2344: 2335: 2334: 2330: 2321: 2319: 2309: 2308: 2304: 2260: 2259: 2255: 2213: 2212: 2208: 2201: 2180: 2179: 2175: 2168: 2147: 2146: 2142: 2129: 2128: 2124: 2115: 2113: 2111:"Hydrocephalus" 2109: 2108: 2104: 2098: 2085: 2084: 2080: 2042: 2041: 2037: 2026:"Hydrocephalus" 2023: 2022: 2018: 1980: 1979: 1968: 1930: 1929: 1925: 1887: 1886: 1879: 1855: 1850: 1849: 1845: 1838: 1826: 1825: 1818: 1807: 1792: 1791: 1787: 1780: 1765: 1764: 1757: 1719: 1718: 1714: 1703: 1695:. p. 117. 1681: 1680: 1673: 1663: 1661: 1655:"Hydrocephalus" 1653: 1652: 1648: 1638: 1636: 1623: 1622: 1575: 1570: 1505: 1480: 1468:H.Res. 373 1449: 1413: 1408: 1326: 1313: 1241: 1225: 1193: 1132: 1127: 1075:juncture points 1042: 1024: 965: 931:third ventricle 905: 873: 807: 775: 688:arachnoid cysts 651: 646: 420: 358:medical imaging 354:normal pressure 237:medical imaging 180: 147: 96: 92: 42: 39: 28: 25:Hydranencephaly 17: 12: 11: 5: 5373: 5371: 5363: 5362: 5357: 5352: 5347: 5337: 5336: 5330: 5329: 5326: 5325: 5323: 5322: 5317: 5312: 5306: 5304: 5300: 5299: 5297: 5296: 5291: 5285: 5283: 5274: 5268: 5267: 5264: 5263: 5261: 5260: 5259: 5258: 5251:Polymicrogyria 5247: 5246: 5245: 5244: 5242:Schizencephaly 5239: 5226: 5225: 5220: 5218:Megalencephaly 5215: 5210: 5204: 5203: 5202: 5201: 5196: 5191: 5186: 5181: 5170: 5169: 5168: 5167: 5157: 5151: 5149: 5145: 5144: 5142: 5141: 5136: 5131: 5130: 5129: 5124: 5119: 5114: 5105: 5103: 5094: 5088: 5087: 5084:nervous system 5078: 5076: 5075: 5068: 5061: 5053: 5044: 5043: 5040: 5039: 5036: 5035: 5033: 5032: 5031: 5030: 5019: 5018: 5017: 5016: 5015: 5014: 5009: 4999: 4994: 4993: 4992: 4987: 4982: 4981: 4980: 4975: 4970: 4962: 4957: 4952: 4947: 4942: 4932: 4918: 4917: 4916: 4915: 4910: 4905: 4891: 4889: 4883: 4882: 4880: 4879: 4874: 4868: 4866: 4857: 4848: 4844: 4843: 4840: 4839: 4837: 4836: 4831: 4826: 4821: 4816: 4811: 4805: 4803: 4799: 4798: 4796: 4795: 4790: 4788:Cerebral edema 4785: 4784: 4783: 4778: 4773: 4768: 4757: 4755: 4749: 4748: 4745: 4744: 4742: 4741: 4740: 4739: 4737:Template:Sleep 4727: 4725: 4721: 4720: 4718: 4717: 4711: 4706: 4700: 4698: 4692: 4691: 4689: 4688: 4682: 4677: 4672: 4666: 4664: 4658: 4657: 4655: 4654: 4648: 4643: 4638: 4632: 4630: 4617: 4609: 4608: 4606: 4605: 4599: 4594: 4589: 4583: 4581: 4575: 4574: 4571: 4570: 4568: 4567: 4565:Leigh syndrome 4561: 4559: 4553: 4552: 4550: 4549: 4538: 4537: 4532: 4527: 4526: 4525: 4511: 4510: 4509: 4504: 4503: 4502: 4486: 4484: 4478: 4477: 4475: 4474: 4469: 4464: 4463: 4462: 4457: 4446: 4445: 4444: 4443: 4438: 4437: 4436: 4426: 4425: 4424: 4414: 4409: 4408: 4407: 4402: 4397: 4392: 4376: 4375: 4374: 4373: 4368: 4363: 4358: 4353: 4352: 4351: 4341: 4340: 4339: 4329: 4328: 4327: 4322: 4317: 4301: 4299: 4292:Extrapyramidal 4285: 4276: 4274:encephalopathy 4265: 4264: 4261: 4260: 4258: 4257: 4252: 4247: 4246: 4245: 4234: 4232: 4225: 4224: 4222: 4221: 4220: 4219: 4209: 4204: 4203: 4202: 4197: 4192: 4187: 4176: 4174: 4165: 4159: 4158: 4151:nervous system 4148: 4146: 4145: 4138: 4131: 4123: 4114: 4113: 4110: 4109: 4098: 4087: 4075: 4074: 4072: 4068: 4067: 4064: 4063: 4052: 4041: 4030: 4003: 3983: 3978: 3977: 3975: 3974:Classification 3968: 3967: 3962: 3951: 3950:External links 3948: 3945: 3944: 3935: 3910: 3884: 3841: 3811: 3781: 3744:BMC Psychiatry 3730: 3711:(6): 419–443. 3695: 3692:on 2007-10-01. 3677:on 2015-07-12. 3662:on 2007-09-16. 3647: 3640: 3634:. p. 53. 3612: 3560: 3545: 3515: 3466: 3417: 3368: 3341:(5): 559–567. 3324: 3275: 3256:(4): 394–396. 3240: 3191: 3166: 3147:(2): 139–141. 3131: 3107: 3096: 3076: 3057: 2994: 2967:(8): 789–790. 2951: 2922: 2901:(2): 179–184. 2881: 2856: 2808: 2789:(3): 179–187. 2773: 2752:(3): 144–147. 2729: 2714: 2711:on 2016-07-27. 2692: 2641: 2626: 2605: 2554: 2529: 2514: 2490: 2471:(4): 342–345. 2454: 2435: 2415: 2396: 2377: 2353: 2337:"Spina Bifida" 2328: 2302: 2273:(8): 463–469. 2253: 2226:(2): 209–214. 2206: 2199: 2173: 2166: 2140: 2137:on 2006-08-20. 2122: 2102: 2096: 2078: 2051:(3): 309–334. 2035: 2016: 1966: 1923: 1877: 1843: 1836: 1816: 1805: 1785: 1778: 1755: 1712: 1701: 1671: 1646: 1572: 1571: 1569: 1566: 1565: 1564: 1558: 1543: 1536: 1526: 1517:Sherman Alexie 1513: 1504: 1501: 1479: 1476: 1455:Hydrocephalus 1448: 1445: 1412: 1409: 1407: 1404: 1400:cerebral shunt 1325: 1322: 1312: 1309: 1257:choroid plexus 1240: 1237: 1224: 1221: 1205:basal cisterns 1176:pleural cavity 1148:cerebral shunt 1131: 1128: 1126: 1123: 1095:nervous tissue 1023: 1020: 1019: 1018: 992: 971:Hydrocephalus 964: 961: 960: 959: 944: 934: 919: 904: 901: 872: 869: 865: 864: 857: 846: 806: 803: 774: 771: 650: 647: 645: 642: 622: 621: 618: 615: 610: 605: 602: 595: 592: 585: 582: 579: 576: 573: 570: 567: 564: 557: 556: 553: 550: 547: 544: 541: 507:abducens nerve 419: 416: 305:, sleepiness, 266: 265: 262: 258: 257: 254: 248: 247: 244: 240: 239: 233: 227: 226: 205: 201: 200: 176:, sleepiness, 167: 161: 160: 155: 149: 148: 146: 145: 89: 87: 83: 82: 66: 65: 57: 56: 53: 49: 48: 40: 15: 13: 10: 9: 6: 4: 3: 2: 5372: 5361: 5358: 5356: 5353: 5351: 5348: 5346: 5343: 5342: 5340: 5321: 5320:Syringomyelia 5318: 5316: 5313: 5311: 5308: 5307: 5305: 5301: 5295: 5292: 5290: 5287: 5286: 5284: 5282: 5278: 5275: 5273: 5269: 5257: 5254: 5253: 5252: 5249: 5248: 5243: 5240: 5238: 5235: 5234: 5233: 5232: 5228: 5227: 5224: 5221: 5219: 5216: 5214: 5211: 5209: 5206: 5205: 5200: 5197: 5195: 5192: 5190: 5187: 5185: 5184:Lissencephaly 5182: 5180: 5177: 5176: 5175: 5172: 5171: 5166: 5163: 5162: 5161: 5158: 5156: 5153: 5152: 5150: 5146: 5140: 5137: 5135: 5134:Encephalocele 5132: 5128: 5125: 5123: 5120: 5118: 5115: 5112: 5111: 5110: 5107: 5106: 5104: 5102: 5098: 5095: 5093: 5089: 5085: 5081: 5074: 5069: 5067: 5062: 5060: 5055: 5054: 5051: 5029: 5026: 5025: 5024: 5021: 5020: 5013: 5010: 5008: 5005: 5004: 5003: 5000: 4998: 4995: 4991: 4988: 4986: 4983: 4979: 4976: 4974: 4971: 4969: 4966: 4965: 4963: 4961: 4958: 4956: 4953: 4951: 4948: 4946: 4943: 4941: 4938: 4937: 4936: 4933: 4931: 4928: 4927: 4926: 4924: 4920: 4919: 4914: 4911: 4909: 4906: 4904: 4901: 4900: 4899: 4897: 4893: 4892: 4890: 4888: 4884: 4878: 4875: 4873: 4870: 4869: 4867: 4865: 4861: 4858: 4856: 4852: 4849: 4845: 4835: 4832: 4830: 4827: 4825: 4822: 4820: 4817: 4815: 4814:Reye syndrome 4812: 4810: 4807: 4806: 4804: 4800: 4794: 4791: 4789: 4786: 4782: 4779: 4777: 4774: 4772: 4769: 4767: 4766:Hydrocephalus 4764: 4763: 4762: 4759: 4758: 4756: 4754: 4750: 4738: 4734: 4733: 4732: 4729: 4728: 4726: 4722: 4716: 4712: 4710: 4707: 4705: 4702: 4701: 4699: 4697: 4693: 4687: 4683: 4681: 4678: 4676: 4673: 4671: 4668: 4667: 4665: 4663: 4659: 4653: 4649: 4647: 4644: 4642: 4639: 4637: 4634: 4633: 4631: 4629: 4625: 4621: 4618: 4616: 4610: 4604: 4600: 4598: 4595: 4593: 4590: 4588: 4585: 4584: 4582: 4580: 4579:Demyelinating 4576: 4566: 4563: 4562: 4560: 4558: 4554: 4548: 4545: 4544: 4543: 4542: 4536: 4533: 4531: 4528: 4524: 4521: 4520: 4519: 4515: 4512: 4508: 4505: 4501: 4498: 4497: 4496: 4493: 4492: 4491: 4488: 4487: 4485: 4483: 4479: 4473: 4470: 4468: 4467:Restless legs 4465: 4461: 4458: 4456: 4453: 4452: 4451: 4448: 4447: 4442: 4439: 4435: 4432: 4431: 4430: 4427: 4423: 4420: 4419: 4418: 4415: 4413: 4410: 4406: 4405:Blepharospasm 4403: 4401: 4398: 4396: 4393: 4391: 4388: 4387: 4386: 4383: 4382: 4381: 4378: 4377: 4372: 4369: 4367: 4364: 4362: 4361:Hemiballismus 4359: 4357: 4354: 4350: 4347: 4346: 4345: 4342: 4338: 4335: 4334: 4333: 4330: 4326: 4323: 4321: 4318: 4316: 4313: 4312: 4311: 4308: 4307: 4306: 4303: 4302: 4300: 4298: 4293: 4289: 4286: 4284: 4280: 4277: 4275: 4270: 4266: 4256: 4253: 4251: 4248: 4244: 4241: 4240: 4239: 4236: 4235: 4233: 4231: 4226: 4218: 4215: 4214: 4213: 4212:Brain abscess 4210: 4208: 4205: 4201: 4198: 4196: 4193: 4191: 4188: 4186: 4183: 4182: 4181: 4178: 4177: 4175: 4173: 4169: 4166: 4164: 4160: 4156: 4152: 4144: 4139: 4137: 4132: 4130: 4125: 4124: 4121: 4108: 4107:Hydrocephalus 4104: 4103: 4099: 4097: 4093: 4092: 4088: 4086: 4082: 4081: 4077: 4076: 4073: 4069: 4062: 4058: 4057: 4053: 4051: 4047: 4046: 4042: 4040: 4036: 4035: 4031: 4029: 4025: 4021: 4017: 4013: 4012: 4008: 4004: 4002: 3998: 3994: 3993: 3989: 3985: 3984: 3981: 3976: 3972: 3966: 3963: 3961: 3957: 3956:Hydrocephalus 3954: 3953: 3949: 3939: 3936: 3924: 3920: 3914: 3911: 3898: 3894: 3888: 3885: 3880: 3876: 3872: 3868: 3864: 3860: 3857:(9583): 262. 3856: 3852: 3845: 3842: 3829: 3825: 3821: 3815: 3812: 3799: 3795: 3791: 3785: 3782: 3777: 3773: 3768: 3763: 3758: 3753: 3749: 3745: 3741: 3734: 3731: 3726: 3722: 3718: 3714: 3710: 3706: 3699: 3696: 3691: 3687: 3683: 3676: 3672: 3671:New Scientist 3668: 3661: 3657: 3651: 3648: 3643: 3641:9781580463126 3637: 3633: 3629: 3625: 3624: 3616: 3613: 3608: 3604: 3600: 3596: 3592: 3588: 3584: 3580: 3573: 3571: 3569: 3567: 3565: 3561: 3556: 3552: 3548: 3542: 3538: 3534: 3530: 3526: 3519: 3516: 3511: 3507: 3503: 3499: 3494: 3489: 3485: 3481: 3477: 3470: 3467: 3462: 3458: 3453: 3448: 3444: 3440: 3436: 3432: 3428: 3421: 3418: 3413: 3409: 3404: 3399: 3395: 3391: 3387: 3383: 3379: 3372: 3369: 3364: 3360: 3356: 3352: 3348: 3344: 3340: 3336: 3328: 3325: 3320: 3316: 3311: 3306: 3302: 3298: 3294: 3290: 3286: 3279: 3276: 3271: 3267: 3263: 3259: 3255: 3251: 3244: 3241: 3236: 3232: 3227: 3222: 3218: 3214: 3210: 3206: 3202: 3195: 3192: 3181: 3177: 3170: 3167: 3162: 3158: 3154: 3150: 3146: 3142: 3135: 3132: 3121: 3117: 3111: 3108: 3103: 3099: 3097:9781604063264 3093: 3089: 3088: 3080: 3077: 3072: 3068: 3061: 3058: 3053: 3047: 3039: 3035: 3030: 3025: 3021: 3017: 3013: 3009: 3005: 2998: 2995: 2990: 2986: 2982: 2978: 2974: 2970: 2966: 2962: 2955: 2952: 2940: 2936: 2932: 2926: 2923: 2918: 2914: 2909: 2904: 2900: 2896: 2892: 2885: 2882: 2870: 2866: 2860: 2857: 2852: 2848: 2844: 2840: 2836: 2832: 2828: 2824: 2817: 2815: 2813: 2809: 2804: 2800: 2796: 2792: 2788: 2784: 2777: 2774: 2769: 2765: 2760: 2755: 2751: 2747: 2743: 2736: 2734: 2730: 2725: 2718: 2715: 2710: 2706: 2702: 2696: 2693: 2688: 2684: 2679: 2674: 2669: 2664: 2660: 2656: 2655:BMC Neurology 2652: 2645: 2642: 2637: 2633: 2629: 2627:9780128040751 2623: 2619: 2612: 2610: 2606: 2601: 2597: 2592: 2587: 2582: 2577: 2573: 2569: 2565: 2558: 2555: 2543: 2539: 2533: 2530: 2525: 2518: 2515: 2504: 2500: 2494: 2491: 2486: 2482: 2478: 2474: 2470: 2466: 2458: 2455: 2442: 2438: 2432: 2428: 2427: 2419: 2416: 2411: 2407: 2400: 2397: 2392: 2388: 2381: 2378: 2367: 2363: 2357: 2354: 2343:on 2013-11-01 2342: 2338: 2332: 2329: 2318: 2317: 2312: 2306: 2303: 2298: 2294: 2289: 2284: 2280: 2276: 2272: 2268: 2264: 2257: 2254: 2249: 2245: 2241: 2237: 2233: 2229: 2225: 2221: 2217: 2210: 2207: 2202: 2196: 2192: 2188: 2184: 2177: 2174: 2169: 2163: 2159: 2155: 2151: 2144: 2141: 2136: 2132: 2126: 2123: 2112: 2106: 2103: 2099: 2093: 2089: 2082: 2079: 2074: 2070: 2066: 2062: 2058: 2054: 2050: 2046: 2039: 2036: 2031: 2027: 2020: 2017: 2012: 2008: 2004: 2000: 1996: 1992: 1988: 1984: 1983:Radiographics 1977: 1975: 1973: 1971: 1967: 1962: 1958: 1954: 1950: 1946: 1942: 1938: 1934: 1927: 1924: 1919: 1915: 1911: 1907: 1903: 1899: 1895: 1891: 1884: 1882: 1878: 1873: 1869: 1865: 1861: 1854: 1847: 1844: 1839: 1837:9780721694931 1833: 1829: 1823: 1821: 1817: 1812: 1808: 1806:9780323448383 1802: 1798: 1797: 1789: 1786: 1781: 1775: 1771: 1770: 1762: 1760: 1756: 1751: 1747: 1743: 1739: 1735: 1731: 1727: 1723: 1716: 1713: 1708: 1704: 1702:9780521806916 1698: 1694: 1691:. Cambridge: 1690: 1689: 1684: 1678: 1676: 1672: 1660: 1656: 1650: 1647: 1634: 1630: 1626: 1620: 1618: 1616: 1614: 1612: 1610: 1608: 1606: 1604: 1602: 1600: 1598: 1596: 1594: 1592: 1590: 1588: 1586: 1584: 1582: 1580: 1578: 1574: 1567: 1562: 1559: 1556: 1552: 1548: 1544: 1541: 1537: 1534: 1530: 1527: 1524: 1523: 1518: 1514: 1511: 1507: 1506: 1503:Notable cases 1502: 1500: 1498: 1492: 1490: 1486: 1477: 1475: 1473: 1469: 1465: 1464:U.S. Congress 1458: 1453: 1446: 1444: 1441: 1429: 1418: 1417:hydrocephalus 1410: 1405: 1403: 1401: 1397: 1396:Carl Wernicke 1393: 1384: 1379: 1374: 1372: 1371:neurosurgical 1368: 1364: 1360: 1359: 1353: 1351: 1347: 1343: 1339: 1330: 1323: 1321: 1318: 1310: 1308: 1305: 1301: 1297: 1295: 1290: 1286: 1285:double vision 1282: 1278: 1274: 1270: 1266: 1262: 1261:hyperesthesia 1258: 1253: 1251: 1247: 1238: 1236: 1234: 1230: 1222: 1220: 1218: 1214: 1213:Benjamin Warf 1210: 1206: 1202: 1198: 1192: 1187: 1185: 1181: 1177: 1173: 1169: 1165: 1161: 1157: 1153: 1149: 1145: 1136: 1129: 1124: 1122: 1120: 1116: 1112: 1108: 1104: 1100: 1096: 1090: 1088: 1082: 1080: 1076: 1072: 1068: 1064: 1059: 1056: 1045: 1037: 1033: 1032:intracerebral 1028: 1021: 1016: 1012: 1011:schizophrenia 1008: 1004: 1000: 996: 993: 990: 986: 982: 979: 978: 974: 969: 962: 957: 953: 949: 945: 942: 938: 935: 932: 928: 924: 920: 917: 913: 910: 909: 908: 902: 898: 893: 889: 887: 883: 879: 871:Communicating 870: 868: 862: 858: 855: 851: 847: 844: 840: 836: 832: 829:secondary to 828: 824: 820: 816: 812: 811: 810: 804: 802: 800: 796: 795:toxoplasmosis 792: 788: 784: 780: 772: 770: 768: 764: 760: 755: 753: 749: 745: 740: 735: 733: 729: 724: 722: 718: 714: 710: 706: 701: 700:cranial bones 697: 693: 689: 685: 680: 678: 674: 673: 663: 655: 648: 643: 641: 639: 635: 631: 627: 619: 616: 614: 611: 609: 606: 603: 600: 596: 593: 590: 586: 583: 580: 577: 574: 571: 568: 565: 562: 561: 560: 554: 551: 548: 545: 542: 539: 538: 537: 535: 530: 528: 524: 520: 516: 512: 508: 504: 500: 496: 493:instability, 492: 487: 486:compression. 485: 481: 477: 473: 469: 465: 461: 457: 452: 450: 449:Hakim's triad 445: 441: 432: 424: 417: 415: 412: 400: 389: 388:hydrocephalus 385: 381: 376: 374: 370: 366: 361: 359: 355: 351: 347: 343: 339: 335: 331: 327: 323: 319: 318:birth defects 314: 312: 308: 304: 300: 296: 292: 291:double vision 288: 284: 280: 276: 272: 271:Hydrocephalus 263: 259: 255: 253: 249: 245: 241: 238: 234: 232: 228: 225: 221: 217: 213: 209: 206: 202: 199: 195: 191: 190:double vision 187: 183: 179: 175: 171: 168: 166: 162: 159: 156: 154: 150: 141: 91: 90: 88: 86:Pronunciation 84: 80: 76: 72: 67: 63: 58: 54: 50: 47:Hydrocephalus 45: 37: 33: 26: 22: 5294:Rachischisis 5289:Spina bifida 5237:Porencephaly 5229: 5173: 5159: 5155:Microcephaly 5127:Iniencephaly 5022: 4921: 4894: 4855:Degenerative 4765: 4592:Inflammatory 4539: 4472:Stiff-person 4310:Parkinsonism 4283:Degenerative 4180:Encephalitis 4163:Inflammation 4153:, primarily 4100: 4089: 4078: 4054: 4043: 4032: 4005: 3986: 3938: 3927:. Retrieved 3913: 3901:. Retrieved 3896: 3887: 3854: 3850: 3844: 3832:. Retrieved 3823: 3814: 3802:. Retrieved 3798:the original 3793: 3784: 3747: 3743: 3733: 3708: 3704: 3698: 3690:the original 3686:ScienceDaily 3685: 3675:the original 3670: 3660:the original 3650: 3622: 3615: 3582: 3578: 3528: 3518: 3483: 3479: 3469: 3434: 3430: 3420: 3388:(1): 22–29. 3385: 3381: 3371: 3338: 3334: 3327: 3292: 3288: 3278: 3253: 3249: 3243: 3208: 3204: 3194: 3183:. Retrieved 3179: 3169: 3144: 3140: 3134: 3123:. Retrieved 3119: 3110: 3086: 3079: 3070: 3060: 3046:cite journal 3011: 3007: 2997: 2964: 2960: 2954: 2943:. Retrieved 2934: 2925: 2898: 2894: 2884: 2873:. Retrieved 2871:. 2017-12-07 2868: 2859: 2826: 2822: 2786: 2782: 2776: 2749: 2745: 2723: 2717: 2709:the original 2704: 2695: 2658: 2654: 2644: 2617: 2571: 2567: 2557: 2546:. Retrieved 2544:. 2020-02-21 2541: 2532: 2523: 2517: 2506:. Retrieved 2502: 2493: 2468: 2464: 2457: 2445:. Retrieved 2425: 2418: 2409: 2399: 2390: 2380: 2369:. Retrieved 2365: 2356: 2345:. Retrieved 2341:the original 2331: 2320:. Retrieved 2314: 2305: 2270: 2266: 2256: 2223: 2219: 2209: 2182: 2176: 2149: 2143: 2135:the original 2125: 2114:. Retrieved 2105: 2088:Spina Bifida 2087: 2081: 2048: 2044: 2038: 2029: 2019: 1986: 1982: 1936: 1932: 1926: 1893: 1889: 1863: 1859: 1846: 1827: 1795: 1788: 1768: 1725: 1721: 1715: 1687: 1683:Stevenson DK 1662:. Retrieved 1658: 1649: 1637:. Retrieved 1628: 1520: 1493: 1481: 1461: 1416: 1414: 1389: 1376: 1356: 1354: 1338:macrocephaly 1335: 1314: 1311:Epidemiology 1306: 1302: 1298: 1254: 1242: 1226: 1194: 1168:right atrium 1141: 1091: 1083: 1079:medical sign 1060: 1051: 1030:Spontaneous 994: 972: 916:colloid cyst 906: 874: 866: 808: 787:brain tumors 776: 759:spina bifida 756: 736: 725: 681: 670: 668: 628:, including 623: 558: 543:Irritability 531: 527:brain tissue 488: 453: 437: 387: 377: 365:shunt system 362: 349: 334:brain tumors 315: 270: 269: 216:brain tumors 182:Older people 181: 169: 158:Neurosurgery 21:Hypocephalus 5272:Spinal cord 5109:Anencephaly 5007:Fazio–Londe 4847:Both/either 4641:Generalised 4500:Early-onset 4495:Alzheimer's 4230:spinal cord 4080:MedlinePlus 2030:MedlinePlus 1639:5 September 1561:Masato Kudo 1555:melon heads 1342:Hippocrates 1246:photophobia 1184:gallbladder 1063:convulsions 1055:spinal cord 927:ependymitis 897:Philippines 854:hypertrophy 835:hemorrhages 791:head trauma 763:meningocele 684:neural-tube 468:papilledema 384:Hippocrates 52:Other names 32:Melon heads 5355:Pediatrics 5339:Categories 5194:Pachygyria 5080:Congenital 4615:paroxysmal 4587:Autoimmune 4380:Dyskinesia 4250:Meningitis 4228:Brain and 4102:Patient UK 4056:DiseasesDB 3929:2014-01-29 3750:(1): 257. 3185:2022-05-18 3125:2022-05-17 3090:. Thieme. 2945:2016-02-10 2875:2022-05-18 2548:2022-05-17 2508:2022-05-17 2371:2020-04-09 2347:2014-01-29 2322:2022-05-17 2116:2022-05-16 1568:References 1533:meningitis 1510:Colby Cave 1348:physician 1281:strabismus 1191:ShuntCheck 1130:Procedures 1125:Treatments 1077:. Another 1015:parenchyma 985:elasticity 859:Bilateral 852:, villous 843:congenital 839:infections 783:meningitis 779:infections 649:Congenital 552:Sleepiness 534:fontanelle 511:gaze palsy 484:brain stem 472:sleepiness 440:chronicity 330:meningitis 212:meningitis 5122:Acalvaria 4612:Episodic/ 4490:Tauopathy 4441:Akathisia 4429:Myoclonus 4412:Athetosis 4344:Tauopathy 4096:neuro/161 4091:eMedicine 3664:Also see 3555:128359318 3295:(1): 29. 3211:: 34–36. 2636:939553425 2574:(1): 17. 2447:12 August 2240:0022-3085 2011:203924869 1485:Marseille 1415:The word 1394:and Key, 1367:Abulcasis 1358:Al-Tasrif 1294:analgesic 1273:migraines 1265:dizziness 1217:infection 1119:brainstem 1101:. 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Index

Hypocephalus
Hydranencephaly
Melon heads
Hydrocephalus (trilobite)

CT scan
lateral ventricles
abnormally large
/ˌhdrˈsɛfələs/
Specialty
Neurosurgery
Symptoms
vomiting
seizures
Headaches
double vision
urinary incontinence
mental impairment
Neural tube defects
meningitis
brain tumors
traumatic brain injury
intraventricular hemorrhage
Diagnostic method
medical imaging
Prognosis
cerebrospinal fluid
brain
pressure inside the skull
headaches

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