31:
90:, may more readily dissolve in the gastrointestinal tract and be absorbed into the bloodstream more quickly. Additionally, many hydrochlorides of amines have a longer shelf-life than their respective free bases.
183:
Myers, Andrew G.; Gleason, James L. (1999). "Asymmetric
Synthesis of α-Amino Acids by the Alkylation of Pseudoephedrine Glycinamide: L-Allylglycine and N-BOC-l-Allylglycine".
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93:
Amine hydrochlorides represent latent forms of a more reactive free base. In this regard, formation of an amine hydrochloride confers
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is a shelf-stable salt that can be readily converted to a reactive glycine methyl ester, a compound that is not shelf-stable.
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248:
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White, James D.; Kranemann, Christian L.; Kuntiyong, Punlop (2002). "4-Methoxycarbonyl-2-methyl-1,3-oxazole".
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lists more than 200 hydrochlorides as active ingredients in medications. These hydrochlorides, compared to
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97:. This effect is illustrated by the hydrochlorides of the amino acids.
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66:, derived from hydrochloric acid's ancient name: muriatic acid.
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into their hydrochlorides is a common way to improve their
62:, which comes from French. An archaic alternative name is
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resulting, or regarded as resulting, from the reaction of
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Pharmaceutical Salts: Properties, Selection, and Use
27:Any salt of an organic base and hydrochloric acid
173:European Pharmacopoeia 7th Edition 2011, EDQM.
8:
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113:, inorganic salts of hydrochloric acid
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99:Glycine methyl ester hydrochloride
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1:
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122:Quaternary ammonium cation
58:). An alternative name is
34:sample of a hydrochloride
224:10.15227/orgsyn.079.0244
197:10.15227/orgsyn.076.0057
84:European Pharmacopoeia
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151:John Wiley & Sons
117:Free base (chemistry)
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141:Stahl, P. Heinrich;
143:Wermuth, Camille G.
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185:Organic Syntheses
160:978-3-90639-051-2
48:hydrochloric acid
16:(Redirected from
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149:(2nd ed.).
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80:water solubility
50:with an organic
38:In chemistry, a
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249:Organochlorides
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60:chlorhydrate
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74:Converting
244:Acid salts
238:Categories
212:Org. Synth
128:References
95:protection
88:free bases
54:(e.g. an
44:acid salt
111:Chloride
105:See also
218:: 244.
64:muriate
18:Muriate
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76:amines
42:is an
254:Salts
56:amine
155:ISBN
70:Uses
52:base
220:doi
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