334:, and it has been observed that surrounding bone tissue with incorporate the new material into its extracellular matrix. Hydroxyapatite is a highly biocompatible material, and its ultrastructural features, such as crystalline orientation, can be controlled carefully to ensure optimal biocompatibility. Proper crystal fiber orientation can make introduced minerals, like hydroxyapatite, more similar to the biological materials they intend to replace. Controlling ultrastructural features makes obtaining specific material properties possible.
89:
36:
1083:
186:
invented the first electron microscope. With the development and invention of this microscope, the range of observable structures that were able to be explored and analyzed increased immensely, as biologists became progressively interested in the submicroscopic organization of cells. This new area of
965:
Orsini, Giovanna; Scarano, Antonio; Piattelli, Maurizio; Piccirilli, Marcello; Caputi, Sergio; Piattelli, Adriano (2006). "Histologic and
Ultrastructural Analysis of Regenerated Bone in Maxillary Sinus Augmentation Using a Porcine Bone–Derived Biomaterial".
1009:
Fujita, Rumi; Yokoyama, Atsuro; Nodasaka, Yoshinobu; Kohgo, Takao; Kawasaki, Takao (2003). "Ultrastructure of ceramic-bone interface using hydroxyapatite and β-tricalcium phosphate ceramics and replacement mechanism of β-tricalcium phosphate in bone".
307:. Since these devices interface directly with bone, their incorporation to surrounding tissue is necessary to optimal device function. It has been found that applying a load to a healing dental implant allows for increased
929:
Meyer, U.; Joos, U.; Mythili, J.; Stamm, T.; Hohoff, A.; Fillies, T.; Stratmann, U.; Wiesmann, H.P. (2004). "Ultrastructural characterization of the implant/bone interface of immediately loaded dental implants".
319:
it is and how the body reacts to it. One study found implanting granules of a biomaterial derived from pig bone caused the human body to incorporate the material into its ultrastructure and form new bone.
878:
Pedraza, Claudio E.; Chien, Yung‐Ching; McKee, Marc D. (2008). "Calcium oxalate crystals in fetal bovine serum: Implications for cell culture, phagocytosis and biomineralization studies in vitro".
280:
crystals, and these crystals are usually considered ultrastructural components of plant cells. Calcium oxalate is a material that is used to manufacture
609:
Cramer, Elisabeth M.; Norol, Françoise; Guichard, Josette; Breton-Gorius, Janine; Vainchenker, William; Massé, Jean-Marc; Debili, Najet (1997-04-01).
1047:"Ultrastructural Observation of Hydroxyapatite Ceramics with Preferred Orientation to a-plane Using High-resolution Transmission Electron Microscopy"
765:
Tilton, V. R.; Horner, H. T. (1980). "Calcium
Oxalate Raphide Crystals and Crystalliferous Idioblasts in the Carpels of Ornithogalum caudatum".
862:
513:
488:
586:
Moreira, Carolina A.; Dempster, David W.; Baron, Roland (2000). "Anatomy and
Ultrastructure of Bone – Histogenesis, Growth and Remodeling".
238:
crystals. It has been theorized that these crystals function to store calcium within the cell until it is needed for growth or development.
164:
way of classifying organisms. Features of ultrastructure are used industrially to control material properties and promote biocompatibility.
455:
75:
122:
153:, which allow the cell to function properly within its specified environment, can be examined at the ultrastructural level.
1103:
138:
142:
57:
46:
117:) is the architecture of cells and biomaterials that is visible at higher magnifications than found on a standard
1087:
363:
118:
531:"Chloroplast Ultrastructure, Chlorophyll Fluorescence, and Pigment Composition in Chilling-Stressed Soybeans"
529:
Musser, Robert L.; Thomas, Shirley A.; Wise, Robert R.; Peeler, Thomas C.; Naylor, Aubrey W. (1984-04-01).
1108:
351:
195:
Many scientists use ultrastructural observations to study the following, including but not limited to:
331:
266:
432:
269:(ECM), so manufacturing materials to mimic ECM allows for increased control over the cell cycle and
157:
53:
911:
833:
648:
355:
297:
293:
852:
1027:
991:
983:
947:
903:
895:
858:
825:
817:
782:
747:
729:
690:
682:
640:
632:
591:
568:
550:
509:
484:
451:
405:
387:
130:
98:
1058:
1019:
975:
939:
887:
809:
774:
737:
721:
622:
558:
542:
476:
443:
413:
395:
377:
316:
308:
611:"Ultrastructure of Platelet Formation by Human Megakaryocytes Cultured With the Mpl Ligand"
667:
327:
312:
277:
235:
134:
943:
778:
742:
709:
563:
530:
480:
400:
326:
is a biomaterial used to interface medical devices directly to bone by ultrastructure.
323:
304:
126:
1023:
265:
uses for controlling the behavior of cells. Cells respond readily to changes in their
1097:
1045:
Zhuang, Zhi; Miki, Takuya; Yumoto, Midori; Konishi, Toshiisa; Aizawa, Mamoru (2012).
854:
Micro and nanoengineering of the cell microenvironment: technologies and applications
800:
Goldfarb, David S. (2004-10-19). "Microorganisms and
Calcium Oxalate Stone Disease".
368:
359:
300:, and is an important aspect of the extracellular matrix for culturing cells.
281:
250:
246:
915:
837:
121:. This traditionally meant the resolution and magnification range of a conventional
652:
447:
315:. Analyzing the ultrastructure surrounding an implant is useful in determining how
289:
161:
1063:
1046:
382:
285:
262:
204:
183:
88:
187:
research concerned itself with substructure, also known as the ultrastructure.
17:
987:
899:
821:
786:
733:
710:"Cellular Ultrastructure and Crystal Development in Amorphophallus (Araceae)"
686:
668:"Sperm ultrastructure and spermatogenesis in the lizard, Tropidurus itambere"
636:
627:
610:
554:
391:
979:
179:
150:
146:
103:
93:
1031:
995:
951:
907:
829:
751:
694:
595:
572:
506:
The
Ultrastructure of Human Tumours: Applications in Diagnosis and Research
409:
364:"Evaluating support for the current classification of eukaryotic diversity"
1082:
644:
417:
253:
could be used to decrease the formation of calcium oxalate kidney stones.
725:
214:
176:
546:
354:; Erika Barbero; Elyse Lasser; Micah Dunthorn; Debashish Bhattacharya;
270:
173:
891:
813:
242:
199:
303:
Ultrastructure is an important factor to consider when engineering
149:
technique for viewing ultrastructure. Such cellular structures as
231:
219:
87:
209:
29:
249:
are a form of these ultrastructural features. Theoretically,
708:
Prychid, C. J.; Jabaily, R. S.; Rudall, P. J. (2008-03-13).
504:
Eyden, B.; Banerjee, S.S.; Ru, Y.; Liberski, P. (2014).
56:. Please help to ensure that disputed statements are
471:
Brieger, E.M. (1963). "Ultrastructure of the Cell".
433:"History of the Electron Microscope in Cell Biology"
125:(TEM) when viewing biological specimens such as
666:Ferreira, Adelina; Dolder, Heidi (1990-01-06).
473:Structure and Ultrastructure of Microorganisms
8:
442:. Chichester: John Wiley & Sons, Ltd.
241:Calcium oxalate crystals can also form in
230:A common ultrastructural feature found in
1062:
741:
626:
590:. South Dartmouth (MA): MDText.com, Inc.
562:
399:
381:
137:. Ultrastructure can also be viewed with
76:Learn how and when to remove this message
52:Relevant discussion may be found on the
343:
7:
276:Many cells, such as plants, produce
27:Detail hidden to optical microscopes
440:Encyclopedia of Life Sciences (ELS)
944:10.1016/j.biomaterials.2003.08.070
779:10.1093/oxfordjournals.aob.a085951
481:10.1016/b978-0-12-134350-7.50005-8
25:
1081:
880:Journal of Cellular Biochemistry
123:transmission electron microscope
34:
431:Masters, Barry R (March 2009).
261:Controlling ultrastructure has
92:The ultrastructure of a single
508:. Springer Berlin Heidelberg.
448:10.1002/9780470015902.a0021539
1:
1024:10.1016/S0040-8166(03)00067-3
145:, although TEM is a standard
1064:10.1016/j.proeng.2012.03.019
851:Khademhosseini, Ali (2008).
383:10.1371/JOURNAL.PGEN.0020220
139:scanning electron microscopy
296:, this crystal is found in
156:Ultrastructure, along with
143:super-resolution microscopy
1125:
330:can be created along with
234:cells is the formation of
968:Journal of Periodontology
475:. Elsevier. p. 1–7.
857:. Boston: Artech House.
628:10.1182/blood.V89.7.2336
119:optical light microscope
102:). The scale bar is 200
980:10.1902/jop.2006.060181
332:𝛃-tricalcium phosphate
107:
352:Laura Wegener Parfrey
91:
1090:at Wikimedia Commons
1051:Procedia Engineering
267:extracellular matrix
45:factual accuracy is
1104:Electron microscopy
547:10.1104/pp.74.4.749
158:molecular phylogeny
802:Nephron Physiology
726:10.1093/aob/mcn022
298:fetal bovine serum
294:tissue engineering
284:, and it also has
108:
1086:Media related to
974:(12): 1984–1990.
938:(10): 1959–1967.
892:10.1002/jcb.21515
864:978-1-59693-149-7
814:10.1159/000080264
515:978-3-642-39168-2
490:978-0-12-134350-7
362:(December 2006).
356:David J Patterson
99:Bacillus subtilis
86:
85:
78:
16:(Redirected from
1116:
1085:
1069:
1068:
1066:
1042:
1036:
1035:
1006:
1000:
999:
962:
956:
955:
926:
920:
919:
886:(5): 1379–1393.
875:
869:
868:
848:
842:
841:
797:
791:
790:
767:Annals of Botany
762:
756:
755:
745:
714:Annals of Botany
705:
699:
698:
672:
663:
657:
656:
630:
621:(7): 2336–2346.
606:
600:
599:
583:
577:
576:
566:
535:Plant Physiology
526:
520:
519:
501:
495:
494:
468:
462:
461:
437:
428:
422:
421:
403:
385:
348:
309:osseointegration
288:properties. For
160:, is a reliable
81:
74:
70:
67:
61:
58:reliably sourced
38:
37:
30:
21:
1124:
1123:
1119:
1118:
1117:
1115:
1114:
1113:
1094:
1093:
1078:
1073:
1072:
1044:
1043:
1039:
1012:Tissue and Cell
1008:
1007:
1003:
964:
963:
959:
928:
927:
923:
877:
876:
872:
865:
850:
849:
845:
799:
798:
794:
764:
763:
759:
707:
706:
702:
670:
665:
664:
660:
608:
607:
603:
585:
584:
580:
528:
527:
523:
516:
503:
502:
498:
491:
470:
469:
465:
458:
435:
430:
429:
425:
350:
349:
345:
340:
305:dental implants
290:culturing cells
278:calcium oxalate
259:
236:calcium oxalate
228:
193:
170:
115:ultra-structure
82:
71:
65:
62:
51:
43:This article's
39:
35:
28:
23:
22:
18:Ultrastructural
15:
12:
11:
5:
1122:
1120:
1112:
1111:
1106:
1096:
1095:
1092:
1091:
1088:Ultrastructure
1077:
1076:External links
1074:
1071:
1070:
1037:
1018:(6): 427–440.
1001:
957:
921:
870:
863:
843:
792:
773:(5): 533–539.
757:
720:(7): 983–995.
700:
681:(3): 353–362.
658:
601:
578:
541:(4): 749–754.
521:
514:
496:
489:
463:
456:
423:
342:
341:
339:
336:
324:Hydroxyapatite
282:ceramic glazes
258:
255:
227:
224:
223:
222:
217:
212:
207:
202:
192:
189:
169:
166:
111:Ultrastructure
94:bacterial cell
84:
83:
42:
40:
33:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1121:
1110:
1107:
1105:
1102:
1101:
1099:
1089:
1084:
1080:
1079:
1075:
1065:
1060:
1056:
1052:
1048:
1041:
1038:
1033:
1029:
1025:
1021:
1017:
1013:
1005:
1002:
997:
993:
989:
985:
981:
977:
973:
969:
961:
958:
953:
949:
945:
941:
937:
933:
925:
922:
917:
913:
909:
905:
901:
897:
893:
889:
885:
881:
874:
871:
866:
860:
856:
855:
847:
844:
839:
835:
831:
827:
823:
819:
815:
811:
807:
803:
796:
793:
788:
784:
780:
776:
772:
768:
761:
758:
753:
749:
744:
739:
735:
731:
727:
723:
719:
715:
711:
704:
701:
696:
692:
688:
684:
680:
676:
669:
662:
659:
654:
650:
646:
642:
638:
634:
629:
624:
620:
616:
612:
605:
602:
597:
593:
589:
582:
579:
574:
570:
565:
560:
556:
552:
548:
544:
540:
536:
532:
525:
522:
517:
511:
507:
500:
497:
492:
486:
482:
478:
474:
467:
464:
459:
457:9780470016176
453:
449:
445:
441:
434:
427:
424:
419:
415:
411:
407:
402:
397:
393:
389:
384:
379:
375:
371:
370:
369:PLOS Genetics
365:
361:
357:
353:
347:
344:
337:
335:
333:
329:
325:
321:
318:
317:biocompatible
314:
310:
306:
301:
299:
295:
291:
287:
283:
279:
274:
272:
268:
264:
256:
254:
252:
248:
247:kidney stones
244:
239:
237:
233:
225:
221:
218:
216:
213:
211:
208:
206:
203:
201:
198:
197:
196:
190:
188:
185:
181:
178:
175:
167:
165:
163:
159:
154:
152:
148:
144:
140:
136:
132:
128:
124:
120:
116:
112:
105:
101:
100:
95:
90:
80:
77:
69:
59:
55:
49:
48:
41:
32:
31:
19:
1109:Cell anatomy
1054:
1050:
1040:
1015:
1011:
1004:
971:
967:
960:
935:
932:Biomaterials
931:
924:
883:
879:
873:
853:
846:
808:(2): 48–54.
805:
801:
795:
770:
766:
760:
717:
713:
703:
678:
674:
661:
618:
614:
604:
587:
581:
538:
534:
524:
505:
499:
472:
466:
439:
426:
376:(12): e220.
373:
367:
360:Laura A Katz
346:
322:
313:facial bones
302:
275:
273:expression.
260:
251:nanobacteria
240:
229:
205:Chloroplasts
200:Human Tumors
194:
191:Applications
171:
162:phylogenetic
155:
114:
110:
109:
97:
72:
63:
44:
1057:: 121–127.
286:biomaterial
263:engineering
257:Engineering
184:Ernst Ruska
1098:Categories
338:References
151:organelles
988:0022-3492
900:0730-2312
822:1660-2137
787:1095-8290
734:0305-7364
687:0327-9545
637:1528-0020
555:0032-0889
418:Q21090155
392:1553-7390
215:Platelets
180:Max Knoll
177:engineers
172:In 1931,
147:histology
54:talk page
1032:14580356
996:17209782
952:14738860
916:43217705
908:17879965
838:29369994
830:15499215
752:18285357
695:15002752
596:25905372
588:Endotext
573:16663504
414:Wikidata
410:17194223
66:May 2017
47:disputed
743:2710233
675:Biocell
653:7757033
645:9116277
564:1066762
401:1713255
271:protein
243:animals
226:Biology
168:History
1030:
994:
986:
950:
914:
906:
898:
861:
836:
828:
820:
785:
750:
740:
732:
693:
685:
651:
643:
635:
594:
571:
561:
553:
512:
487:
454:
416:
408:
398:
390:
328:Grafts
245:, and
174:German
135:organs
131:tissue
912:S2CID
834:S2CID
671:(PDF)
649:S2CID
615:Blood
436:(PDF)
311:with
232:plant
220:Sperm
133:, or
127:cells
1028:PMID
992:PMID
984:ISSN
948:PMID
904:PMID
896:ISSN
859:ISBN
826:PMID
818:ISSN
783:ISSN
748:PMID
730:ISSN
691:PMID
683:ISSN
641:PMID
633:ISSN
592:PMID
569:PMID
551:ISSN
510:ISBN
485:ISBN
452:ISBN
406:PMID
388:ISSN
292:and
210:Bone
182:and
141:and
113:(or
1059:doi
1020:doi
976:doi
940:doi
888:doi
884:103
810:doi
775:doi
738:PMC
722:doi
718:101
623:doi
559:PMC
543:doi
477:doi
444:doi
396:PMC
378:doi
1100::
1055:36
1053:.
1049:.
1026:.
1016:35
1014:.
990:.
982:.
972:77
970:.
946:.
936:25
934:.
910:.
902:.
894:.
882:.
832:.
824:.
816:.
806:98
804:.
781:.
771:46
769:.
746:.
736:.
728:.
716:.
712:.
689:.
679:27
677:.
673:.
647:.
639:.
631:.
619:89
617:.
613:.
567:.
557:.
549:.
539:74
537:.
533:.
483:.
450:.
438:.
412:.
404:.
394:.
386:.
372:.
366:.
358:;
129:,
104:nm
1067:.
1061::
1034:.
1022::
998:.
978::
954:.
942::
918:.
890::
867:.
840:.
812::
789:.
777::
754:.
724::
697:.
655:.
625::
598:.
575:.
545::
518:.
493:.
479::
460:.
446::
420:.
380::
374:2
106:.
96:(
79:)
73:(
68:)
64:(
60:.
50:.
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.