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and biases—measures that are now standard practice. Prof. Zelen helped transform clinical trial research into a well-managed and statistically sophisticated branch of medical science. His work in this area has led to significant medical advances, such as improved treatments for several different forms of cancer. His research also focused on improved early detection of cancer; on modeling the progression of cancer and its response to treatment; and on using statistical models to help determine optimal screening strategies for various common cancers, especially breast cancer.
760:. The matter made headlines, wound up in court, and was chronicled in the book A Civil Action, which was later made into a movie. As the book notes, when Prof. Zelen announced the study's results in the basement of a Woburn church in February 1984, someone in the audience called out, “Thank God for Marvin Zelen,” and the crowd burst into applause.
284:. His research also focused on improved early detection of cancer; on modeling the progression of cancer and its response to treatment; and on using statistical models to help determine optimal screening strategies for various common cancers, especially breast cancer. Ironically, he died after a prolonged battle with cancer.
797:- have all spoken of Zelen's huge influence. Said Kalbfleisch, “Marvin was a tremendous force in the profession and a great mentor to so many of his colleagues and students.” Prentice said Prof. Zelen “did much to define the biostatistical profession.” Breslow said he was “greatly influenced by Marvin and his work.”
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School established the annual Marvin Zelen
Leadership Award in Statistical Science, which has become one of the most prestigious awards in the field, meant to reflect Prof. Zelen's contributions to quantitative science and beyond. The Marvin Zelen Leadership Award in Statistical Science, Awarded annually by the
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Zelen has received numerous awards and honors. His work has been recognized around the world through awards and other accolades. He has received numerous awards, among them from ASA, ISI, IMS; he is a fellow of the
American Academy of Arts and Sciences. In 1997, in honor of his 70th birthday, the
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Another of Zelen's achievements was his establishment, in 1975, of the
Frontier Science and Technology Research Foundation in Boston, a nonprofit devoted to advancing the use of statistical science and practice and data management techniques in science, health care, and education. Prof. Zelen served
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Zelen was noted for his developing some of the statistical methods and study designs still used in clinical cancer trials, in which experimental drugs are tested for toxicity, effectiveness, and proper dosage. He introduced measures to ensure that data gathered from human trials would be as free as
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alumni magazine article in 2008, Zelen said those early studies were “terrible.” He said the studies were “poorly thought out; the data was wrong; they had poor quality control, not enough patients — everything you can think of that was antiscientific.” He urged biomedical researchers in charge of
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Zelen was known for developing the statistical methods and study designs that are used in clinical cancer trials, in which experimental drugs are tested for toxicity, effectiveness, and proper dosage. He also introduced measures to ensure that data from the trials are as free as possible of errors
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In the mid-1970s, Zelen's pioneering work in
Buffalo brought him to the attention of HSPH's then-biostatistics chair, Frederick Mosteller. Zelen insisted that he would only come to Harvard if he could bring the biostatistics team which he had built in Buffalo, since he wanted to build the world's
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This is another excellent example of how Marvin established an environment within which others could flourish. Thelma’s contributions to Marvin’s success cannot be overlooked. Their partnership is a role model of working together, and she has been a major force in the formation and administrative
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Scientists from around the world have benefited from Dr. Zelen’s innovative ideas and transformative effect on biomedical research, but those of us associated with the
Harvard Department of Biostatistics are particularly grateful for Dr. Zelen’s commitment to educating students and advancing the
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a tremendous force in my personal and professional life. He was always in and out of my office, asking how things were going. Even as he was trying to convince me to do something I absolutely did not want to do, I always felt his intentions for me were the best. Marvin was always honest and
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Research
Professor of Statistical Science (the first recipient). During the 1980s, Zelen chaired HSPH's Department of Biostatistics. Among colleagues in the field of statistics, he was widely known as a leader who shaped the discipline of biostatistics. He "transformed
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the studies to begin from scratch because they had learned relatively little because of study design flaws. They agreed with Zelen, and along with his longtime collaborator Paul
Carbone, he established research standards and practice now used in clinical trials for many
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2007 - R.A. Fisher
Lectureship, Fisher Lecturer Award, Committee of the Presidents of the Statistical Society (COPSS), in recognition of his outstanding contributions to statistical science. Award Lecture: "The early detection of disease: Statistical
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as president, and his wife Thelma was chief administrative officer. Several of his other close friends and
Harvard colleagues were also directly involved. Richard D. Gelber, professor of biostatistics of HSPH and at DFCI, and winner of the 2008
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department — which it is and has been for quite some time. It was an enormously exciting time when we were united in working towards a common goal. Marvin’s genius was that he got all of us involved, then stepped back and gave us all the credit.”
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Zelen also achieved another level of fame in the early 1980s when he and his late colleague (died 2009) in the biostatistics department, Stephen
Lagakos, launched a study of a possible connection between a cluster of childhood leukemia cases in
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Mandelblatt, JS; Cronin, KA; Bailey, S; Berry, DA; de Koning, HJ; Draisma, G; Huang, H; Lee, SJ; Munsell, M; Plevritis, SK; Ravdin, P; Schechter, CB; Sigal, B; Stoto, MA; Stout, NK; van Ravesteyn, NT; Venier, J; Zelen, M; Feuer, EJ (Nov 2009).
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and the town's water supply. Known as the Harvard Health Study, the investigation showed, for the first time, a connection between Woburn's contaminated water and a variety of adverse health effects, including
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1 - 2007 (January 23–25) - International Biometric Society (EMR-IBS), 1st day of the 4th meeting of the Eastern Mediterranean Region at the Hilton Hotel, Eilat, Israel, was a dedicated symposium for Dr. Marvin
610:, which focused on overseeing and improving statistical aspects of large, complex drug trials. ECOG would later become one of the world's largest programs for testing and evaluating various cancer treatments.
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So many people were helped by Marvin, whether they needed assistance with starting a company, with a personal matter, or with ideas and guidance in academic statistics. That is truly a legacy to be proud of.
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in Boston. They administer three other major annual statistical awards, in the spirit of Zelen's aspirations to make the HSPH Biostatistics Department number one among the world's academic biostatistics
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1975 - Founder, President, Chairman of Board, Frontier Science & Technology Research Foundation (a notfor–profit foundation devoted to the advancement of statistical science in clinical trials)
657:, recalled that “those first few years of integrating twelve new faculty members from Buffalo with half as many from Harvard were part of Marvin’s grand plan to make Harvard the nation's leading
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2012 - Nicholas P. Jewell, Professor, Division of Biostatistics, School of Public Health; Professor, Department of Statistics, University of California, Berkeley, “Counting Civilian Casualties”
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During the past 39 years, Marvin taught me much about the importance of collaborative research, and how progress is fueled by statistical and clinical scientists working together as partners.
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Wallace, BC; Zelen, M; Zani Pacheco, CL (Dec 1998). "Milk leakage in nonlactating women: a randomized clinical trial evaluating a polyvinyl chloride device versus disposable breast pads".
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2311:"Awarded newly-established Lemuel Shattuck Research Professorship in Statistical Science, established and named by Harvard President Derek Bok, effective September 1, 2007"
2165:"Awarded newly-established Lemuel Shattuck Research Professorship in Statistical Science, established and named by Harvard President Derek Bok, effective September 1, 2007"
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Awarded newly-established Lemuel Shattuck Research Professorship in Statistical Science, established and named by Harvard President Derek Bok, effective September 1, 2007
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Mandelblatt, JS; Cronin, KA; Berry, DA; Chang, Y; de Koning, HJ; Lee, SJ; Plevritis, SK; Schechter, CB; Stout, NK; van Ravesteyn, NT; Zelen, M; Feuer, EJ (Oct 2011).
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greatest biostatistics department wherever he went. Thus, in 1977, 27 faculty, researchers, and other staff members moved from Buffalo to Boston, along with their
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Shen, Y; Zelen, M (Aug 2001). "Screening sensitivity and sojourn time from breast cancer early detection clinical trials: mammograms and physical examinations".
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Conference Information, David W. Warne (Editor), International Society for Clinical Biostatistics, 2006 (December), Number 42, page 36 (top left corner of page)
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747:, and improved the biostatistics curriculum. As its chair, he helped propel the department to its position as a leading center for biostatistical research.
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Joy Adamson & Sarah Cockayne & David J. Torgerson, Zelen's randomized consent design, Encyclopedia of Research Design, Neil J. Salkind, Ed., 2010,
669:'s Department of Biostatistics, where he has been credited with transforming HSPH's biostatistics department into the best biostatistics department in the
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Zelen has had work published in more than 150 publications. The most complete list published in one place is on his profile page in the Harvard Catalyst.
307:. Because the group to which any given patient is assigned is known at the time of consenting, the study patient's consent can be sought conditionally.
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Mitchell H. Gail, MD, PhD, senior investigator in the biostatistics branch of NCI's Division of Cancer Epidemiology and Genetics and president of the
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Zelen was survived by his wife, Thelma Geier Zelen, and their two daughters, Deborah and Sandy Zelen, and by two grandsons, Matthew and Toby Mues.
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computer and their research projects, the ECOG trials — 150 cancer trials involving several thousand patients. Zelen's lab was established at the
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COPSS, TABLE 1.4 Recipients of the R.A. Fisher Lectureship (cont’d), Past, Present, and Future of Statistical Science, CRC Press, page 15 (middle)
2353:"Stephen Lagakos, international leader in biostatistics and AIDS research, dies," HSPH memorial news release for Stephen Lagakos, October 13, 2009
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Berry, DA; Cronin, KA; Plevritis, SK; Fryback, DG; Clarke, L; Zelen, M; Mandelblatt, JS; Yakovlev, AY; Habbema, JD; Feuer, EJ (Oct 2005).
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Profile page for Mitchell H. Gail of the National Cancer Institute's Division of Cancer Epidemiology & Genetics, Biostatistics Branch
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1037:???? - Lecturer, Mortimer and Raymond Sackler Institute of Advanced Studies, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.
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2013 - John J. Crowley, PhD, President and CEO of Cancer Research And Biostatistics (CRAB), “A Brief History of Survival Analysis”
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as Biostatistics Chair. He continued working on the ECOG trials, helped lay the groundwork for the department's pre-eminence in
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Parmigiani, G; Skates, S; Zelen, M (Mar 2002). "Modeling and optimization in early detection programs with a single exam".
2477:"John Crowley honored with Zelen Leadership Award", SWOG announcement of Crowley's award, April 20-13, accessed 11/21/2014
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280:. His work in this area led to significant medical advances, such as improved treatments for several different forms of
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Minibio of Jewell, The Third Joint Biostatistics Symposium, Chengdu, Sichuan, China, June 25-28, 2014Accessed 11/21/2014
571:
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1271:"Effects of mammography screening under different screening schedules: model estimates of potential benefits and harms"
887:, for developing statistical analysis for evaluating policies, particularly in education, and for his contributions to
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255:(June 21, 1927 – November 15, 2014) was Professor Emeritus of Biostatistics in the Department of Biostatistics at the
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546:’s Mathematics Research Center, where he first worked with cancer researchers, helping them address problems with
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621:” during the early 1970s. He was chair of a committee responsible for designing and organizing the new program.
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Zelen, M (Dec 2004). "Forward and backward recurrence times and length biased sampling: age specific models".
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Lee, S; Huang, H; Zelen, M (Dec 2004). "Early detection of disease and scheduling of screening examinations".
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847:, PhD, Dean of the Graduate School of Arts & Sciences and Whipple V.N. Jones Professor of Statistics at
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1513:"Robust modeling in screening studies: estimation of sensitivity and preclinical sojourn time distribution"
2019:
Nam, CM; Zelen, M (Mar 2001). "Comparing the survival of two groups with an intermediate clinical event".
851:, "Personalized Treatment: Sounds heavenly, but where on Earth did they find the right guinea pig for me?"
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719:, long before the study section supported it. He inspired the clinical trials community of statisticians.
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Marvin had a lot of guts and a vision for what was important. He finagled NCI into supporting the use of
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or Zelen's randomized consent design, in which patients are randomized to either the treatment or to the
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2003 - Docteur, Honoris Causa (honorary doctoral degree), Universite Victor Segalen Bordeaux II, France
864:, “Methods for Investigating Agreement & Concordance: with Applications in the Biomedical Sciences”
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Zelen, M; Lee, SJ (2002). "Models and the early detection of disease: methodological considerations".
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and statistics section, where he delved further into cancer and clinical research. He spent a year in
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Davidov, O; Zelen, M (Aug 2000). "Designing cancer prevention trials: a stochastic model approach".
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2012 - Karl E. Peace award for "Outstanding Statistical Contributions for the Betterment of Society"
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2544:"Frontier Science Foundation-Hellas (FSF-H) website announcement of the Lagakos Symposium, Athens"
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1996 announcement of the establishment of the Marvin Zelen Leadership Award in Statistical Science
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Esha Senchaudhuri, 2014 Zelen Award Honors Statistician and Educator, 2014, accessed 11/21/2014
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Parzen Prize Lecture to Feature World-Renowned Statisticians, May 12, 2008, Accessed 11/21/2014
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Esha Senchaudhuri, 2014 Zelen Award Honors Statistician and Educator, 2014, accessed 11/21/2014
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Lee, SJ; Zelen, M (2002). "Statistical models for screening: planning public health programs".
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possible of errors and biases—measures that are now standard practice. Zelen helped transform
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933:, “The Case-Control Study: Origins, Modern Conception and Newly Available Methods of Analysis”
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1192:"Modeling the impact of population screening on breast cancer mortality in the United States"
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1996 - Clair and Richard Morse Award for outstanding achievement in advancing cancer research
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2002 - Robert O’Neill, “A Perspective on the Development and Future on Statistics at the FDA”
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1096:’s highest honor, in recognition of his accomplishments in Cancer Research (November 2009).
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Shen, Y; Wu, D; Zelen, M (Dec 2001). "Testing the independence of two diagnostic tests".
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Cytel (provider of biostatistics and operations research software and service knowledge)
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He was the only math lab employee without a doctorate, which he later earned in 1957 at
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685:, and voted to remain an Emeritus Professor there, also, until his death in late 2014.
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1132:- "Impact of Biostatistical Science - Advances in Research: AIDS, Cancer, Environment"
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2008 - Emanuel & Carol Prize for Statistical Innovation (Texas A&M University)
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Fellow biostatisticians from around the country—people like Jack Kalbfleisch from the
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In the early 1960s, Zelen spent two years (1961-1963) as a visiting professor at the
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993:, “Deciding Whether Large Clinical Trials and Meta-analyses (deceased) Agree or Not”
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leadership of Frontier Science as its chief operating officer for almost 40 years.
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2003:
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2007 - Lifetime Achievement Award (International Indian Statistical Association)
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1966 - Washington Academy of Science Award for distinguished work in mathematics
1000:, “A Smorgasbord of Handy Techniques That Can Help in (deceased) Analyzing Data”
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In 2007, Zelen became the first holder of the newly named (by Harvard President
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Zelen’s colleague and successor (as Department Chair), biostatistics professor
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1805:"Experimental design issues for the early detection of disease: novel designs"
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2286:"'About' page, Frontier Science & Technology Research Foundation website"
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Lecture, with Nancy Reid, Department of Statistics, Texas A&M University
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and, adding his voice of praise for Prof. Zelen's mentorship and generosity
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there. After earning a master's degree in mathematical statistics from the
444:
443:, Lemuel Shattuck Research Professor of Statistical Science (established by
82:
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Awardees of the annual Marvin Zelen Leadership Award in Statistical Science
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2011:
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1997-2000 - Chair, Committee of Presidents of Statistical Societies (COPSS)
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1470:"Effect of screening and adjuvant therapy on mortality from breast cancer"
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944:, “The Symbiosis of Statistical Science and Biomedicine: Past and Future”
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2070:
10.1002/1097-0258(20000815)19:15<1983::aid-sim534>3.0.co;2-e
625:, HSPH biostatistics professor, called Zelen's involvement in the early
1235:"Effect of screening mammography on breast-cancer mortality in Norway"
606:. During that period, Zelen formed the Statistical Laboratory at the
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1373:
1356:
1137:
Play the Winner: Honoring the Scientific Achievements of Marvin Zelen
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692:) Lemuel Shattuck Research Professor of Statistical Science at HSPH.
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Dana-Farber/Harvard Center Center profile page for Richard D. Gelber
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Zelen served for a decade in the 1980s (1981-1990) as chair of the
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Zelen, M (Nov 2003). "The training of biostatistical scientists".
1400:"A stochastic model for predicting the mortality of breast cancer"
1025:
Elected Fellow of the American Academy of Arts and Sciences (AAAS)
827:. The Awards Committee is in the Biostatistics Department of the
589:(ECOG) — one of several regional organizations established by the
1770:"The theory of case-control studies for early detection programs"
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Three symposia have been held around the world in Zelen's honor:
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into a statistically sophisticated branch of medical research."
2402:
Awards and Lectureships of the HSPH Department of Biostatistics
969:, “The Analysis of Case-Control Data to Detect Candidate Genes”
202:
Frontier Science & Technology Research Foundation (Founmer)
2424:
HSPH Biostatistics Department announcement of 2014 Zelen Award
646:, where, simultaneously with his tenure at HSPH, he built the
527:
in 1951, he worked for 10 years at the mathematics lab of the
276:
into a well-managed and statistically sophisticated branch of
1018:, “The Importance of Clinical Trials in Education” (deceased)
962:, “Chronic Disease Prevention: Research Strategies and Needs”
903:
theory, “Measures of Heterogeneity. Diversity and Inequality”
1040:
1965-1966 - Fulbright Senior Lecturer Award (United Kingdom)
1028:
Member, American Association for the Advancement of Science
550:. After that, for four years beginning in 1963, he led the
2607:
David Reich, "Thank God for Marvin Zelen", August 15, 2008
955:, “Absolute Risk: Clinical Applications and Controversies”
723:
On a more personal level, Zelen's colleague and successor
650:’s Department of Biostatistics and Computational Biology.
1357:"Biostatisticians, biostatistical science and the future"
1233:
Kalager, M; Zelen, M; Langmark, F; Adami, HO (Sep 2010).
1171:
Current HSPH biostatistics chair Victor de Gruttola said
910:, “Challenges in Clinical Trials; Some Old and Some New”
499:, where he attended and in 1944 received a diploma from
511:, he discovered and developed his lifelong interest in
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2642:Harvard T.H. Chan School of Public Health faculty
585:During his 10 years in Buffalo, Zelen helped the
1735:"Modelling the early detection of breast cancer"
1314:"Mortality modeling of early detection programs"
386:National Institute of Standards & Technology
183:National Institute of Standards & Technology
2687:Fellows of the American Statistical Association
1548:"Planning of randomized early detection trials"
1014:, (former) Chair, Department of Biostatistics,
519:. In 1949, he earned his bachelor's degree in
2196:HSPH Biostatistics Department Zelen Award page
1154:Boards, Chairmanship, and Professional Service
766:Komen Brinker Award for Scientific Distinction
479:London School of Hygiene and Tropical Medicine
312:Fellow of the American Statistical Association
234:London School of Hygiene and Tropical Medicine
976:, “Analytic Studies with Complex Survey Data”
8:
2672:University of Maryland, College Park faculty
2208:"Lagakos Symposium profile for Marvin Zelen"
1007:, “Graphical Models in Statistics: A Review”
470:Imperial College of Science & Technology
229:Imperial College of Science & Technology
2569:"DFCI site for "Play the Winner" Symposium"
1663:"Overdiagnosis in early detection programs"
525:University of North Carolina at Chapel Hill
343:University of North Carolina at Chapel Hill
103:University of North Carolina at Chapel Hill
2375:Legacy.com local obituary for Marvin Zelen
466:- early 1960s (2 years, from 1961 to 1963)
419:(Buffalo), Professor and Leading Professor
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681:, in the FAS Department of Statistics in
257:Harvard T.H. Chan School of Public Health
1287:10.7326/0003-4819-151-10-200911170-00010
2682:University of Wisconsin–Madison faculty
2667:Stevens Institute of Technology faculty
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1052:2004 - A special issue of the journal
1031:American Statistical Association (ASA)
986:, “Event Histories and Their Analysis”
931:Statistical Methods in Cancer Research
791:Fred Hutchinson Cancer Research Center
613:Zelen was also prominent in President
1148:American Academy of Arts and Sciences
1092:2009 (November 11) - Medal of Honor,
885:Stanford Graduate School of Education
7:
2717:Mathematicians from New York (state)
2712:21st-century American mathematicians
2707:20th-century American mathematicians
1034:Institute of Mathematical Statistics
495:Marvin Zelen was born and reared in
491:Early life and career before Harvard
2622:University of North Carolina alumni
2131:Cluster randomised controlled trial
436:, Professor of Statistical Science
429:, Professor of Statistical Science
395:(College Park), Associate Professor
917:, for developing and popularizing
871:, Professor and Chair Emeritus of
587:Eastern Cooperative Oncology Group
459:University of California, Berkeley
219:University of California, Berkeley
25:
1918:. Cancer Treatment and Research.
1879:. Cancer Treatment and Research.
1768:Davidov, O; Zelen, M (Jul 2003).
1661:Davidov, O; Zelen, M (Oct 2004).
128:Zelen's randomized consent design
2632:City College of New York faculty
1967:10.1111/j.0006-341x.2001.01009.x
1852:10.1111/j.0006-341x.2002.00030.x
1331:10.1111/j.1541-0420.2007.00893.x
1065:American Statistical Association
953:American Statistical Association
825:American Statistical Association
701:American Statistical Association
2637:City College of New York alumni
1016:Harvard School of Public Health
829:Harvard School of Public Health
673:. He was also a member of the
667:Harvard School of Public Health
441:Harvard School of Public Health
434:Harvard School of Public Health
372:Stevens Institute of Technology
310:In 1962 Zelen was elected as a
210:Harvard School of Public Health
173:Stevens Institute of Technology
2266:View/Search Fellows of the ASA
1733:Lee, SJ; Zelen, M (Aug 2003).
1511:Shen, Y; Zelen, M (Oct 2005).
1435:"Risks of cancer and families"
1312:Lee, SJ; Zelen, M (Jun 2008).
1176:careers of junior scientists.
1061:Samuel S. Wilks Memorial Award
793:, and Norman Breslow from the
595:experimental cancer treatments
402:’s Mathematics Research Center
18:Marvin Zelen (biostatistician)
1:
2722:Scientists from New York City
2677:University at Buffalo faculty
1822:10.1093/biostatistics/3.3.299
1787:10.1093/biostatistics/4.3.411
1417:10.1093/jncimonographs/lgj011
1208:10.1016/S0960-9776(11)70299-5
1139:, Simmons College, Boston, MA
2702:American medical researchers
2521:Announcement of Parzen Prize
1803:Hu, P; Zelen, M (Sep 2002).
1680:10.1093/biostatistics/kxh012
1546:Hu, P; Zelen, M (Dec 2004).
1530:10.1093/biostatistics/kxi030
675:Faculty of Arts and Sciences
648:Dana–Farber Cancer Institute
644:Dana–Farber Cancer Institute
572:State University of New York
529:National Bureau of Standards
427:Dana–Farber Cancer Institute
417:State University of New York
382:National Bureau of Standards
205:Dana–Farber Cancer Institute
198:State University of New York
179:National Bureau of Standards
2004:10.1200/jco.2001.19.15.3490
1928:10.1007/978-1-4757-3571-0_1
1889:10.1007/978-1-4757-3571-0_2
929:, in their two-volume work
800:Again, Mitchell H. Gail of
2743:
2727:21st-century American Jews
2627:American University alumni
633:Academic career at Harvard
629:“tremendous and lasting.”
597:— with its studies. In an
501:Evander Childs High School
325:Evander Childs High School
293:randomized clinical trials
2657:Jewish American academics
2436:"CV for Dr. Xiao-Li Meng"
2381:Friday, November 17, 2014
1638:10.1007/s10985-004-4770-1
1601:10.1191/0962280204sm377ra
1564:10.1191/0962280204sm379ra
1404:J Natl Cancer Inst Monogr
1398:Lee, S; Zelen, M (2006).
1135:3 - 2013 (November 25) -
1120:2 - 2010 (October 2–3) -
951:, Past President (1995),
802:National Cancer Institute
789:, Ross Prentice from the
736:In 1981, Zelen succeeded
591:National Cancer Institute
566:, and then he joined the
552:National Cancer Institute
407:National Cancer Institute
246:
193:National Cancer Institute
142:
795:University of Washington
509:City College of New York
332:City College of New York
93:City College of New York
27:Biostatistics researcher
2121:American Cancer Society
2099:10.1089/jwh.1998.7.1283
2033:10.1023/a:1009609925212
1094:American Cancer Society
940:, cofounder of journal
544:University of Wisconsin
464:University of Wisconsin
452:Visiting faculty member
400:University of Wisconsin
347:mathematical statistics
303:before they give their
274:clinical trial research
266:clinical trial research
224:University of Wisconsin
107:mathematical statistics
95:, New York City, B.S.,
2275:, accessed 2016-07-23.
1178:
1054:Lifetime Data Analysis
811:
787:University of Michigan
783:
775:
734:
721:
393:University of Maryland
188:University of Maryland
2239:10.4135/9781412961288
1752:10.1093/annonc/mdg323
1433:Zelen, M (Nov 2005).
1355:Zelen, M (Oct 2006).
1252:10.1056/NEJMoa1000727
1173:
1056:was dedicated to him.
897:multivariate analysis
806:
779:
770:
729:
705:
608:University of Buffalo
580:University at Buffalo
327:, New York City, 1944
72:Boston, Massachusetts
1589:Stat Methods Med Res
1552:Stat Methods Med Res
1487:10.1056/NEJMoa050518
1005:Sir David Roxbee Cox
893:statistics education
200:(Buffalo), 1967-1977
2377:, published in the
1452:10.1093/jnci/dji386
1202:(Suppl 3): S75–81.
1012:Frederick Mosteller
881:Stanford University
738:Frederick Mosteller
703:(1995), commented:
604:infectious diseases
599:American University
556:applied mathematics
537:American University
376:Hoboken, New Jersey
354:American University
289:experimental design
236:(London) - visiting
231:(London) - visiting
162:experimental design
113:American University
2652:Cancer researchers
2271:2016-06-16 at the
2021:Lifetime Data Anal
1626:Lifetime Data Anal
1439:J Natl Cancer Inst
1122:Lagakos' Symposium
849:Harvard University
679:Harvard University
570:department at the
214:Harvard University
54:New York, New York
2662:Jewish scientists
1937:978-1-4419-5310-0
1916:Cancer Treat. Res
1898:978-1-4419-5310-0
1877:Cancer Treat. Res
925:, with co-author
915:Norman E. Breslow
862:J. Richard Landis
817:Honors and awards
564:Fulbright Scholar
485:Hebrew University
474:Fulbright Scholar
334:, New York City,
250:
249:
240:Hebrew University
144:Scientific career
64:November 15, 2014
16:(Redirected from
2734:
2647:Biostatisticians
2595:
2590:
2584:
2583:
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2580:
2571:. Archived from
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2546:. Archived from
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2328:
2323:on March 4, 2016
2322:
2316:. Archived from
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2288:. Archived from
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2210:. Archived from
2204:
2198:
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2182:
2177:on March 4, 2016
2176:
2170:. Archived from
2169:
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2146:Stochastic model
2110:
2087:J Women's Health
2081:
2052:
2015:
1986:
1949:
1910:
1871:
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1799:
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1710:10.1002/sim.1642
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1374:10.1002/sim.2658
1351:
1333:
1308:
1298:
1264:
1254:
1229:
1219:
1167:Collegial praise
991:Lincoln E. Moses
967:Robert C. Elston
960:Ross L. Prentice
949:Mitchell H. Gail
923:research designs
533:Washington, D.C.
305:informed consent
67:
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2064:(15): 1983–95.
2055:
2018:
1989:
1952:
1938:
1913:
1899:
1874:
1837:
1802:
1767:
1745:(8): 1199–202.
1732:
1704:(21): 3427–30.
1695:
1660:
1623:
1586:
1545:
1510:
1480:(17): 1784–92.
1467:
1432:
1397:
1367:(20): 3409–14.
1354:
1311:
1267:
1245:(13): 1203–10.
1232:
1189:
1183:
1169:
1156:
921:matched sample
908:David L. DeMets
819:
745:clinical trials
732:unpretentious.
717:clinical trials
715:) computers in
635:
493:
367:
320:
278:medical science
261:Lemuel Shattuck
237:
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89:Alma mater
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1281:(10): 738–47.
1275:Ann Intern Med
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683:Harvard Square
634:
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593:(NCI) to test
503:. Then, as a
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132:Zelen's design
125:
124:Known for
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68:(aged 87)
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2575:on 2016-03-04
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2550:on 2014-12-21
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2292:on 2015-04-14
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2255:9781412961288
2252:
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2247:9781412961271
2244:
2240:
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2214:on 2014-12-21
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2147:
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2141:Randomization
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2126:Breast Cancer
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2122:
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1853:
1849:
1845:
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1823:
1818:
1814:
1810:
1809:Biostatistics
1806:
1801:
1797:
1793:
1788:
1783:
1780:(3): 411–21.
1779:
1775:
1774:Biostatistics
1771:
1766:
1762:
1758:
1753:
1748:
1744:
1740:
1736:
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1723:
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1703:
1699:
1694:
1690:
1686:
1681:
1676:
1673:(4): 603–13.
1672:
1668:
1667:Biostatistics
1664:
1659:
1655:
1651:
1647:
1643:
1639:
1635:
1632:(4): 325–34.
1631:
1627:
1622:
1618:
1614:
1610:
1606:
1602:
1598:
1595:(6): 443–56.
1594:
1590:
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1569:
1565:
1561:
1557:
1553:
1549:
1544:
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1526:
1523:(4): 604–14.
1522:
1518:
1517:Biostatistics
1514:
1509:
1505:
1501:
1497:
1493:
1488:
1483:
1479:
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1471:
1466:
1462:
1458:
1453:
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1436:
1431:
1427:
1423:
1418:
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1410:(36): 79–86.
1409:
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1370:
1366:
1362:
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1332:
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1324:(2): 386–95.
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1036:
1033:
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1024:
1023:
1017:
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1006:
1002:
999:
998:John W. Tukey
995:
992:
988:
985:
984:Niels Keiding
981:
978:
975:
971:
968:
964:
961:
957:
954:
950:
946:
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942:Biostatistics
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889:meta-analysis
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671:United States
668:
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659:biostatistics
656:
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645:
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632:
630:
628:
627:war on cancer
624:
620:
619:war on cancer
616:
615:Richard Nixon
611:
609:
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583:
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568:biostatistics
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287:One of those
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158:biostatistics
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55:
50:June 21, 1927
42:
38:
31:
19:
2588:
2577:. Retrieved
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