806:
830:
842:
818:
67:
is added and the response is measured again. Ideally, the standard addition should increase the analyte concentration by a factor of 1.5 to 3, and several additions should be averaged. The volume of standard solution should be small enough to disturb the matrix as little as possible.
54:
using standard samples with known analyte concentration and which try to approximate the matrix of the sample as much as possible. This is especially important for solid samples where there is a strong matrix influence. In cases with complex or unknown matrices, the
213:
The concentration of analyte in both standards should be the same. A matrix effect value close to 100 indicates absence of matrix influence. A matrix effect value of less than 100 indicates suppression, while a value larger than 100 is a sign of matrix enhancement.
332:
199:
337:
The advantages of this definition are that negative values indicates suppression, while positive values are a sign of matrix enhancement. Ideally, a value of 0 is related to the absence of matrix effect.
46:
of interest. The matrix can have a considerable effect on the way the analysis is conducted and the quality of the results are obtained; such effects are called matrix effects. For example, the
451:
366:
524:
753:
50:
of the solution can have an effect on the activity coefficients of the analytes. The most common approach for accounting for matrix effects is to build a
776:
564:
81:
223:
96:
517:
846:
493:
439:
411:
822:
783:
549:
868:
810:
510:
554:
630:
620:
701:
661:
56:
790:
671:
579:
59:
can be used. In this technique, the response of the sample is measured and recorded, for example, using an
769:
347:
569:
625:
589:
541:
533:
666:
829:
696:
691:
686:
559:
77:
76:
Matrix enhancement and suppression is frequently observed in modern analytical routines, such as
762:
737:
732:
722:
635:
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574:
489:
435:
407:
64:
51:
39:
31:
834:
742:
465:
380:
615:
47:
862:
681:
461:
376:
717:
640:
610:
456:
371:
676:
584:
17:
645:
469:
384:
60:
207:
A(extract) is the peak area of analyte, when diluted with matrix extract.
327:{\displaystyle ME=100\left({\frac {A(extract)}{A(standard)}}\right)-100}
502:
43:
460:, 2nd ed. (the "Gold Book") (1997). Online corrected version: (1989) "
375:, 2nd ed. (the "Gold Book") (1997). Online corrected version: (1989) "
194:{\displaystyle ME=100\left({\frac {A(extract)}{A(standard)}}\right)}
27:
Components of a chemical sample other than the substance of interest
210:
A(standard) is the peak area of analyte in the absence of matrix.
217:
An alternative definition of matrix effect utilizes the formula:
506:
226:
99:
90:
is quantitated by the use of the following formula:
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654:
603:
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63:selective for the analyte. Then, a small volume of
326:
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8:
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116:
98:
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777:Analytical and Bioanalytical Chemistry
565:High-performance liquid chromatograph
394:
392:
7:
817:
841:
457:Compendium of Chemical Terminology
400:Environmental Analytical Chemistry
372:Compendium of Chemical Terminology
25:
840:
828:
816:
805:
804:
550:Atomic absorption spectrometer
428:Quantitative Chemical Analysis
308:
281:
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181:
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146:
122:
38:refers to the components of a
1:
398:F. W. Fifield, P. J. Haines.
482:Trends in Sample Preparation
480:Marco Aurelio Zezzi Arruda.
555:Flame emission spectrometer
885:
800:
631:Ion mobility spectrometry
621:Electroanalytical methods
402:. Blackwell Publishing,
57:standard addition method
791:Analytical Biochemistry
580:Melting point apparatus
470:10.1351/goldbook.M03759
385:10.1351/goldbook.M03758
770:Analytica Chimica Acta
348:Extraction (chemistry)
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195:
662:Coning and quartering
570:Infrared spectrometer
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196:
869:Analytical chemistry
784:Analytical Chemistry
626:Gravimetric analysis
590:Optical spectrometer
534:Analytical chemistry
377:Matrix (in analysis)
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97:
484:. Nova Publishers,
430:, 4th ed. Freeman,
697:Separation process
692:Sample preparation
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191:
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738:Standard addition
733:Internal standard
723:Calibration curve
636:Mass spectrometry
595:Spectrophotometer
575:Mass spectrometer
560:Gas chromatograph
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65:standard solution
52:calibration curve
32:chemical analysis
16:(Redirected from
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743:Isotope dilution
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754:publications
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718:Chemometrics
702:Sub-sampling
641:Spectroscopy
488:, p. 15-18.
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847:WikiProject
711:Calibration
672:Dissolution
611:Calorimetry
84:, and ICP.
752:Prominent
677:Filtration
604:Techniques
585:Microscope
406:, p. 4-5.
354:References
646:Titration
319:−
61:electrode
863:Category
811:Category
667:Dilution
655:Sampling
342:See also
823:Commons
763:Analyst
682:Masking
204:where
44:analyte
835:Portal
492:
438:
410:
40:sample
36:matrix
452:IUPAC
367:IUPAC
490:ISBN
486:2006
436:ISBN
432:1995
408:ISBN
404:2000
82:HPLC
466:doi
464:".
381:doi
379:".
322:100
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