25:
117:
223:. A high MPV is also a bad prognostic marker in patients with sepsis or septic shock. In addition, low MPV may correlate with abnormally small platelet size, sometimes a symptom of a spectrum referred to as
162:. Since the average platelet size is larger when the body is producing increased numbers of platelets, the MPV test results can be used to make inferences about platelet production in
567:
Lippi G, Filippozzi L, Salvagno GL, Montagnana M, Franchini M, Guidi GC, Targher G (September 2009). "Increased mean platelet volume in patients with acute coronary syndromes".
35:
1010:
827:
1402:
1407:
1354:
472:
1063:
1392:
330:
518:
Slavka, Georg; Perkmann, Thomas; Haslacher, Helmuth; Greisenegger, Stefan; Marsik, Claudia; Wagner, Oswald F.; Endler, Georg (February 2012).
761:
1003:
1288:
1397:
842:
1339:
1073:
852:
1376:
96:
1300:
68:
1435:
996:
325:
173:
1202:
230:
Sample for MPV testing is obtained in a
Lavender-Top EDTA tube. A typical range of platelet volumes is 7.2 - 11.7 fL (
75:
1329:
1087:
378:
288:
224:
181:
1324:
389:
335:
43:
1246:
1212:
1058:
82:
934:"Mean platelet volume may represent a predictive parameter for overall vascular mortality and ischemic heart disease"
520:"Mean Platelet Volume May Represent a Predictive Parameter for Overall Vascular Mortality and Ischemic Heart Disease"
1334:
1185:
212:
177:
967:
Bessman JD, Gilmer PR, Gardner FH (1985). "Use of mean platelet volume improves detection of platelet disorders".
54:
39:
1295:
1092:
293:
64:
1172:
370:
1256:
1068:
920:
1190:
1082:
1053:
449:
415:
356:
268:
1387:
1366:
1142:
821:
444:
137:
can be used to make inferences about platelet production in bone marrow or platelet destruction problems
273:
1468:
1317:
1283:
1154:
1030:
715:
313:
159:
1167:
784:"Normal range of mean platelet volume in healthy subjects: Insight from a large epidemiologic study"
1312:
420:
89:
1116:
1111:
868:
549:
303:
220:
298:
216:
890:
1445:
1218:
976:
955:
848:
803:
743:
684:
635:
584:
541:
405:
932:
Slavka G, Perkmann T, Haslacher H, Greisenegger S, Marsik C, Wagner OF, Endler G (May 2011).
1344:
1241:
1236:
1179:
1162:
945:
795:
733:
723:
674:
666:
625:
615:
576:
531:
425:
196:
782:
Demirin H, Ozhan H, Ucgun T, Celer A, Bulur S, Cil H, Gunes C, Yildirim HA (May 28, 2011).
1129:
434:
351:
308:
208:
719:
1440:
1349:
1278:
1099:
1048:
738:
703:
679:
654:
630:
603:
439:
345:
341:
263:
169:
An increased mean platelet volume (MPV) increases the risk to suffer a heart disease
1462:
1268:
1251:
1195:
1148:
604:"Mean platelet volume: a controversial marker of disease activity in Crohn's disease"
410:
200:
185:
1430:
1361:
1137:
799:
477:
258:
253:
702:
Gao Y, Li Y, Yu X, Guo S, Ji X, Sun T, et al. (2014-08-13). Stover CM (ed.).
728:
553:
1228:
1207:
395:
204:
163:
950:
933:
670:
536:
519:
1425:
1305:
1261:
1043:
1038:
1022:
1019:
704:"The impact of various platelet indices as prognostic markers of septic shock"
400:
235:
231:
189:
172:
MPV may be higher when there is destruction of platelets. This may be seen in
155:
655:"Platelet Indices and Their Kinetics Predict Mortality in Patients of Sepsis"
783:
620:
959:
807:
747:
688:
639:
588:
545:
980:
988:
454:
282:
278:
151:
1371:
580:
53:
if you can. Unsourced or poorly sourced material may be challenged and
429:
992:
602:
Liu S, Ren J, Han G, Wang G, Gu G, Xia Q, Li J (October 2012).
18:
150:) is a machine-calculated measurement of the average size of
500:
891:"Bernard-Soulier Syndrome Workup: Approach Considerations"
919:
Davis PD, Nabili SN (27 August 2020). Shiel Jr WC (ed.).
50:
482:
Familial platelet disorder with predisposition to AML
227:(WAS), caused by a genetic mutation of the WAS gene.
659:
Indian
Journal of Hematology & Blood Transfusion
1418:
1227:
1127:
1029:
133:
128:
938:Arteriosclerosis, Thrombosis, and Vascular Biology
524:Arteriosclerosis, Thrombosis, and Vascular Biology
921:"What Is Thrombocytopenia (Low Platelet Count)?"
569:Archives of Pathology & Laboratory Medicine
1403:aPTT-based activated protein C resistance test
49:Please review the contents of the article and
1408:ETP-based activated protein C resistance test
1004:
653:Mangalesh S, Dudani S, Malik A (March 2021).
195:Abnormally low MPV values may correlate with
8:
826:: CS1 maint: multiple names: authors list (
154:found in blood and is typically included in
473:Congenital amegakaryocytic thrombocytopenia
1011:
997:
989:
461:Inherited thrombocytopenia with normal MPV
234:), equivalent to spheres 2.65 to 2.9
1064:Mean corpuscular hemoglobin concentration
949:
889:Geil GD (7 August 2020). Yaish HM (ed.).
737:
727:
678:
629:
619:
535:
199:when it is due to impaired production of
1393:Ristocetin-induced platelet aggregation
1355:Activated protein C–protein C inhibitor
492:
819:
331:Disseminated intravascular coagulation
242:Conditions associated with altered MPV
125:
847:. Lippincott Williams & Wilkins.
7:
1436:Nitro blue tetrazolium chloride test
608:European Journal of Medical Research
1398:Activated protein C resistance test
375:Mediterranean macrothrombocytopenia
279:Acquired Immunodeficiency Syndrome
166:or platelet destruction problems.
14:
1289:Dilute Russell's viper venom time
1074:Red blood cell distribution width
1301:Calibrated automated thrombogram
115:
23:
174:immune thrombocytopenic purpura
1330:Coagulation activation markers
1203:Erythrocyte sedimentation rate
895:emedicine.staging.medscape.com
800:10.1016/j.thromres.2011.05.007
764:. Immune Deficiency Foundation
51:add the appropriate references
1:
1340:Thrombin–antithrombin complex
1088:White blood cell differential
1325:Overall hemostatic potential
844:Clinical Laboratory Medicine
729:10.1371/journal.pone.0103761
501:"Complete Blood Count (CBC)"
390:Chronic myelogenous leukemia
336:Myeloproliferative disorders
188:and recovery from transient
184:. It may also be related to
1247:Partial thromboplastin time
1213:Monocyte distribution width
1059:Mean corpuscular hemoglobin
178:myeloproliferative diseases
36:reliable medical references
1485:
1186:Hemoglobin electrophoresis
951:10.1161/ATVBAHA.110.221788
869:"Paris-Trousseau syndrome"
762:"Wiskott-Aldrich Syndrome"
671:10.1007/s12288-021-01411-2
537:10.1161/ATVBAHA.110.221788
213:inflammatory bowel disease
1335:Prothrombin fragments 1+2
1296:Thrombin generation assay
1093:Absolute neutrophil count
469:Thrombocytopenia 2 (THC2)
294:X linked thrombocytopenia
211:. A low MPV may indicate
42:or relies too heavily on
379:Bernard–Soulier syndrome
371:Paris-Trousseau syndrome
350:Recovery from transient
289:Wiskott–Aldrich syndrome
225:Wiskott–Aldrich syndrome
182:Bernard–Soulier syndrome
1257:Activated clotting time
1069:Mean corpuscular volume
621:10.1186/2047-783x-17-27
450:Artificial heart valves
386:21q11 deletion syndrome
326:Immune thrombocytopenia
264:Reactive thrombocytosis
16:Component of blood test
1191:Sickle solubility test
1083:White blood cell count
1054:Red blood cell indices
841:McClatchey KD (2002).
416:Chronic kidney disease
383:MYH9-related disorders
357:Gray platelet syndrome
269:Iron-deficiency anemia
65:"Mean platelet volume"
1388:Von Willebrand factor
1367:Euglobulin lysis time
1306:ST Genesia-based test
445:Myocardial infarction
1381:-antiplasmin complex
1318:Thrombodynamics test
1284:Ecarin clotting time
1173:Kleihauer–Betke test
1105:Mean platelet volume
1049:Red blood cell count
1031:Complete blood count
421:Respiratory diseases
314:Megaloblastic anemia
144:Mean platelet volume
129:Mean platelet volume
1313:Thromboelastography
788:Thrombosis Research
720:2014PLoSO...9j3761G
1143:Total blood volume
1117:Reticulocyte index
1112:Reticulocyte count
581:10.5858/133.9.1441
455:Massive hemorrhage
340:Administration of
304:Ulcerative colitis
274:Gilbert's syndrome
221:ulcerative colitis
1456:
1455:
1446:Immunophenotyping
1219:Osmotic fragility
406:Diabetes mellitus
367:Platelet Type vWD
141:
140:
124:
123:
100:
1476:
1345:Fibrinopeptide A
1242:Prothrombin time
1237:Clotting factors
1180:Hemoglobinopathy
1163:Fetal hemoglobin
1013:
1006:
999:
990:
984:
963:
953:
928:
905:
904:
902:
901:
886:
880:
879:
877:
876:
865:
859:
858:
838:
832:
831:
825:
817:
815:
814:
779:
773:
772:
770:
769:
758:
752:
751:
741:
731:
699:
693:
692:
682:
650:
644:
643:
633:
623:
599:
593:
592:
564:
558:
557:
539:
530:(5): 1215–1218.
515:
509:
508:
497:
426:Thrombocytopenia
197:thrombocytopenia
126:
119:
118:
110:
107:
101:
99:
58:
27:
26:
19:
1484:
1483:
1479:
1478:
1477:
1475:
1474:
1473:
1459:
1458:
1457:
1452:
1431:Blood viscosity
1414:
1380:
1350:Fibrin monomers
1223:
1168:Apt–Downey test
1155:Red cell volume
1130:red blood cells
1128:Other tests of
1123:
1025:
1017:
987:
966:
931:
925:Medicinenet.com
918:
914:
912:Further reading
909:
908:
899:
897:
888:
887:
883:
874:
872:
867:
866:
862:
855:
840:
839:
835:
818:
812:
810:
781:
780:
776:
767:
765:
760:
759:
755:
701:
700:
696:
652:
651:
647:
601:
600:
596:
566:
565:
561:
517:
516:
512:
499:
498:
494:
489:
463:
435:Hyperthyroidism
361:GATA-1 mutation
322:
309:Aplastic anemia
299:Crohn's disease
249:
244:
217:Crohn's disease
215:(IBD), such as
209:aplastic anemia
158:as part of the
120:
116:
111:
105:
102:
59:
48:
44:primary sources
28:
24:
17:
12:
11:
5:
1482:
1480:
1472:
1471:
1461:
1460:
1454:
1453:
1451:
1450:
1449:
1448:
1441:Flow cytometry
1438:
1433:
1428:
1422:
1420:
1416:
1415:
1413:
1412:
1411:
1410:
1405:
1395:
1390:
1385:
1384:
1383:
1378:
1374:
1369:
1359:
1358:
1357:
1352:
1347:
1342:
1337:
1327:
1322:
1321:
1320:
1310:
1309:
1308:
1303:
1293:
1292:
1291:
1286:
1281:
1279:Reptilase time
1271:
1266:
1265:
1264:
1259:
1254:
1249:
1244:
1233:
1231:
1225:
1224:
1222:
1221:
1216:
1210:
1205:
1200:
1199:
1198:
1193:
1188:
1177:
1176:
1175:
1170:
1160:
1159:
1158:
1152:
1146:
1134:
1132:
1125:
1124:
1122:
1121:
1120:
1119:
1109:
1108:
1107:
1100:Platelet count
1097:
1096:
1095:
1090:
1080:
1079:
1078:
1077:
1076:
1071:
1066:
1061:
1046:
1041:
1035:
1033:
1027:
1026:
1018:
1016:
1015:
1008:
1001:
993:
986:
985:
964:
929:
915:
913:
910:
907:
906:
881:
860:
853:
833:
794:(4): 358–360.
774:
753:
714:(8): e103761.
694:
665:(4): 600–608.
645:
594:
559:
510:
491:
490:
488:
485:
484:
483:
480:
475:
470:
467:
466:ATRUS Syndrome
462:
459:
458:
457:
452:
447:
442:
440:Hypothyroidism
437:
432:
423:
418:
413:
408:
403:
398:
392:
387:
384:
381:
376:
373:
368:
365:
362:
359:
354:
348:
346:thrombopoietin
342:erythropoietin
338:
333:
328:
321:
318:
317:
316:
311:
306:
301:
296:
291:
286:
276:
271:
266:
261:
256:
248:
245:
243:
240:
201:megakaryocytes
139:
138:
135:
131:
130:
122:
121:
114:
112:
31:
29:
22:
15:
13:
10:
9:
6:
4:
3:
2:
1481:
1470:
1467:
1466:
1464:
1447:
1444:
1443:
1442:
1439:
1437:
1434:
1432:
1429:
1427:
1424:
1423:
1421:
1417:
1409:
1406:
1404:
1401:
1400:
1399:
1396:
1394:
1391:
1389:
1386:
1382:
1375:
1373:
1370:
1368:
1365:
1364:
1363:
1360:
1356:
1353:
1351:
1348:
1346:
1343:
1341:
1338:
1336:
1333:
1332:
1331:
1328:
1326:
1323:
1319:
1316:
1315:
1314:
1311:
1307:
1304:
1302:
1299:
1298:
1297:
1294:
1290:
1287:
1285:
1282:
1280:
1277:
1276:
1275:
1274:animal enzyme
1272:
1270:
1269:Bleeding time
1267:
1263:
1260:
1258:
1255:
1253:
1252:Thrombin time
1250:
1248:
1245:
1243:
1240:
1239:
1238:
1235:
1234:
1232:
1230:
1226:
1220:
1217:
1214:
1211:
1209:
1206:
1204:
1201:
1197:
1196:Mentzer index
1194:
1192:
1189:
1187:
1184:
1183:
1181:
1178:
1174:
1171:
1169:
1166:
1165:
1164:
1161:
1156:
1153:
1150:
1149:Plasma volume
1147:
1144:
1141:
1140:
1139:
1136:
1135:
1133:
1131:
1126:
1118:
1115:
1114:
1113:
1110:
1106:
1103:
1102:
1101:
1098:
1094:
1091:
1089:
1086:
1085:
1084:
1081:
1075:
1072:
1070:
1067:
1065:
1062:
1060:
1057:
1056:
1055:
1052:
1051:
1050:
1047:
1045:
1042:
1040:
1037:
1036:
1034:
1032:
1028:
1024:
1021:
1014:
1009:
1007:
1002:
1000:
995:
994:
991:
982:
978:
975:(1): 127–35.
974:
970:
965:
961:
957:
952:
947:
944:(5): 1215–8.
943:
939:
935:
930:
926:
922:
917:
916:
911:
896:
892:
885:
882:
870:
864:
861:
856:
854:9780683307511
850:
846:
845:
837:
834:
829:
823:
809:
805:
801:
797:
793:
789:
785:
778:
775:
763:
757:
754:
749:
745:
740:
735:
730:
725:
721:
717:
713:
709:
705:
698:
695:
690:
686:
681:
676:
672:
668:
664:
660:
656:
649:
646:
641:
637:
632:
627:
622:
617:
613:
609:
605:
598:
595:
590:
586:
582:
578:
575:(9): 1441–3.
574:
570:
563:
560:
555:
551:
547:
543:
538:
533:
529:
525:
521:
514:
511:
506:
502:
496:
493:
486:
481:
479:
476:
474:
471:
468:
465:
464:
460:
456:
453:
451:
448:
446:
443:
441:
438:
436:
433:
431:
428:secondary to
427:
424:
422:
419:
417:
414:
412:
411:Pre-eclampsia
409:
407:
404:
402:
399:
397:
393:
391:
388:
385:
382:
380:
377:
374:
372:
369:
366:
363:
360:
358:
355:
353:
349:
347:
343:
339:
337:
334:
332:
329:
327:
324:
323:
320:Increased MPV
319:
315:
312:
310:
307:
305:
302:
300:
297:
295:
292:
290:
287:
284:
280:
277:
275:
272:
270:
267:
265:
262:
260:
259:Hypersplenism
257:
255:
251:
250:
247:Decreased MPV
246:
241:
239:
238:in diameter.
237:
233:
228:
226:
222:
218:
214:
210:
207:, such as in
206:
202:
198:
193:
191:
187:
186:pre-eclampsia
183:
179:
175:
170:
167:
165:
161:
157:
153:
149:
145:
136:
132:
127:
113:
109:
106:November 2021
98:
95:
91:
88:
84:
81:
77:
74:
70:
67: –
66:
62:
61:Find sources:
56:
52:
46:
45:
41:
37:
32:This article
30:
21:
20:
1362:Fibrinolysis
1273:
1138:Blood volume
1104:
972:
968:
941:
937:
924:
898:. Retrieved
894:
884:
873:. Retrieved
863:
843:
836:
822:cite journal
811:. Retrieved
791:
787:
777:
766:. Retrieved
756:
711:
707:
697:
662:
658:
648:
611:
607:
597:
572:
568:
562:
527:
523:
513:
504:
495:
478:TAR syndrome
254:chemotherapy
229:
194:
171:
168:
147:
143:
142:
103:
93:
86:
79:
72:
60:
40:verification
33:
1469:Blood tests
1229:Coagulation
1208:Haptoglobin
1023:blood tests
969:Blood Cells
871:. MrLabTest
505:Testing.com
396:splenectomy
364:vWD Type 2B
205:bone marrow
164:bone marrow
156:blood tests
34:needs more
1426:Blood film
1262:Fibrinogen
1044:Hematocrit
1039:Hemoglobin
1020:Hematology
900:2018-02-22
875:2022-05-10
813:2024-05-25
768:2019-03-03
487:References
401:Vasculitis
352:hypoplasia
252:Cytotoxic
232:femtolitre
190:hypoplasia
76:newspapers
1377:Plasmin-α
614:(1): 27.
152:platelets
1463:Category
1182:testing
960:21330610
808:21620440
748:25118886
708:PLOS ONE
689:33776267
640:23058104
589:19722752
546:21330610
1372:D-Dimer
981:4074887
739:4131909
716:Bibcode
680:7988247
631:3519557
203:in the
176:(ITP),
134:Purpose
90:scholar
55:removed
979:
958:
851:
806:
746:
736:
687:
677:
638:
628:
587:
552:
544:
430:sepsis
92:
85:
78:
71:
63:
1419:Other
1215:(MDW)
1157:(RCV)
1145:(TBV)
554:85367
550:S2CID
394:Post-
97:JSTOR
83:books
1151:(PV)
977:PMID
956:PMID
849:ISBN
828:link
804:PMID
744:PMID
685:PMID
636:PMID
585:PMID
542:PMID
283:AIDS
219:and
180:and
69:news
38:for
946:doi
796:doi
792:128
734:PMC
724:doi
675:PMC
667:doi
626:PMC
616:doi
577:doi
573:133
532:doi
160:CBC
148:MPV
1465::
973:11
971:.
954:.
942:31
940:.
936:.
923:.
893:.
824:}}
820:{{
802:.
790:.
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