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344:"Gleaning non-trivial structural, functional and evolutionary information about proteins by iterative database searches"
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containing ACT domains supports the suggestions that these domains contain the archetypical ACT
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215:. The ACT domain is named after three of the proteins that contain it:
268:
236:. The archetypical ACT domain is the C-terminal regulatory domain of
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that is found in a variety of proteins involved in metabolism. ACT
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Chipman DM, Shaanan B (December 2001). "The ACT domain family".
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aspartokinase iii in complex with aspartate and adp (r-state)
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The ACT domain was discovered by
Aravind and Koonin using
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This article incorporates text from the public domain
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16:Self-stabilizing region of a metabolic protein
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309:Current Opinion in Structural Biology
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342:Aravind L, Koonin EV (April 1999).
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251:-like topology. A pair of ACT
201:are linked to a wide range of
1:
321:10.1016/S0959-440X(01)00272-X
129:Available protein structures:
348:Journal of Molecular Biology
288:iterative sequence searches
275:exploration of a few other
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189:In molecular biology, the
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271:bound in the interface.
255:form an eight-stranded
360:10.1006/jmbi.1999.2653
208:that are regulated by
33:Crystal structure of
238:3-phosphoglycerate
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178:structure summary
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227:horismate mutase
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739:Protein domains
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423:Protein domains
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259:sheet with two
243:(3PGDH), which
220:spartate kinase
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354:(5): 1023–40.
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195:protein domain
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241:dehydrogenase
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257:antiparallel
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190:
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34:
718:zinc finger
273:Biochemical
43:Identifiers
294:References
267:inhibitor
265:allosteric
249:ferredoxin
210:amino acid
191:ACT domain
141:structures
606:EcoEI_R_C
388:IPR002912
281:structure
261:molecules
203:metabolic
87:IPR002912
733:Category
384:InterPro
368:10222208
329:11751050
277:proteins
158:RCSB PDB
82:InterPro
636:Kringle
529:CGI-121
499:BTB/POZ
253:domains
247:with a
206:enzymes
199:domains
119:cd02116
62:PF01842
35:E. coli
366:
327:
269:serine
173:PDBsum
147:
137:
107:SUPFAM
75:CL0070
48:Symbol
651:NACHT
574:Pyrin
554:Death
519:Cache
454:ADF-H
245:folds
193:is a
103:SCOPe
94:SCOP2
703:WD40
698:TRIO
631:HEAT
626:FYVE
621:FGGY
616:ENTH
596:DHR2
591:DHR1
586:DHHC
569:CARD
549:CVHN
504:BZIP
479:BESS
464:ARID
459:ANTH
444:ACDC
382:and
380:Pfam
364:PMID
325:PMID
229:and
166:PDBj
162:PDBe
145:ECOD
135:Pfam
99:1psd
71:clan
69:Pfam
57:Pfam
713:YTH
693:SUN
688:SH3
683:SH2
668:PDZ
661:LOV
656:PAS
646:LRR
641:LIM
611:EF1
581:DEP
564:DED
544:CUT
539:CUB
534:CRM
524:CBS
494:BPS
489:BMC
484:BIR
474:BEN
469:BAR
449:ACT
439:ABM
356:doi
352:287
317:doi
263:of
234:yrA
153:PDB
114:CDD
51:ACT
22:ACT
735::
708:X8
678:PX
673:PH
601:DM
559:DD
514:C2
509:C1
434:3H
386::
362:.
350:.
346:.
323:.
313:11
311:.
290:.
283:.
222:,
164:;
160:;
143:/
105:/
101:/
415:e
408:t
401:v
370:.
358::
331:.
319::
232:T
225:c
218:a
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
