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with a pale halo, appearing within 10 to 15 min after emotional upset. There have been 10 cases described in medical literature, and involve a trigger (coffee, intense emotions) followed by a rise in
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The underlying mechanisms are not fully understood, but existing research suggests that adrenergic urticaria is linked with elevated serum
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Hogan, Sara R.; Mandrell, Joshua; Eilers, David (2014). "Adrenergic urticaria: Review of the literature and proposed mechanism".
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105:, which suppresses the rash and prevents further exacerbations. Skin biopsy specimens of adrenergic urticaria show
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levels. The characteristic halo hives are most likely caused by catecholamine-induced peripheral
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The diagnosis of AU can be made either clinically or by giving an intradermal injection of
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is a skin condition characterized by an eruption consisting of small (1-5mm) red
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tissues with a vague inflammatory infiltrate, and electron microscopy reveals
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Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007).
101:, which causes the rash, or by monitoring the body's reaction to
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256:"Dupilumab as a novel therapy to treat adrenergic urticaria"
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James, William; Berger, Timothy; Elston, Dirk (2005).
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81:wheals, which is consistent with other types of
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260:Annals of Allergy, Asthma & Immunology
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254:Goodman, Brian; Jariwala, Sunit (2021).
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185:. St. Louis: Mosby. p. 267.
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141:List of cutaneous conditions
266:(2). Elsevier BV: 205–206.
219:(4). Elsevier BV: 763–766.
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273:10.1016/j.anai.2020.06.034
225:10.1016/j.jaad.2013.10.062
183:Dermatology: 2-Volume Set
320:Urticaria and angioedema
163:. (10th ed.). Saunders.
61:and trigger avoidance.
57:. Treatment involves
39:Adrenergic urticaria
22:Adrenergic urticaria
126:Aquagenic urticaria
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136:Skin lesion
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32:Dermatology
147:References
95:adrenaline
282:1081-1206
233:0190-9622
131:Urticaria
111:mast cell
107:edematous
89:Diagnosis
83:urticaria
65:Mechanism
28:Specialty
314:Category
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120:See also
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