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36:
3913:
3901:
666:. This often occurs when patients fail to inform their physician and pharmacist of all the medications they are taking, including herbal and dietary supplements. The new medication may interact agonistically or antagonistically (potentiate or decrease the intended therapeutic effect), causing significant
463:
In principle, medical professionals are required to report all adverse effects related to a specific form of therapy. In practice, it is at the discretion of the professional to determine whether a medical event is at all related to the therapy. As a result, routine adverse effects reporting often
441:
in
Dunedin is New Zealand's national monitoring centre for adverse reactions. It collects and evaluates spontaneous reports of adverse reactions to medicines, vaccines, herbal products and dietary supplements from health professionals in New Zealand. Currently the CARM database holds over 80,000
450:
In Canada, adverse reaction reporting is an important component of the surveillance of marketed health products conducted by the Health
Products and Food Branch (HPFB) of Health Canada. Within HPFB, the Marketed Health Products Directorate leads the coordination and implementation of consistent
739:
studies to determine the nonadverse effect level (NOAEL). These studies are used to define the dosage to be used in human testing (phase I), as well as to calculate the maximum admissible daily intake. Imperfections in clinical trials, such as insufficient number of patients or short duration,
421:(ADEC). Reporting is voluntary, and ADRAC requests healthcare professionals to report all adverse reactions to its current drugs of interest, and serious adverse reactions to any drug. ADRAC publishes the Australian Adverse Drug Reactions Bulletin every two months. The Government's
264:
In terms of drugs, adverse events may be defined as: "Any untoward medical occurrence in a patient or clinical investigation subject administered a pharmaceutical product and which does not necessarily have to have a causal relationship with this treatment."
1249:). No link has been found in several large studies, and despite removal of thimerosal from most early childhood vaccines beginning with those manufactured in 2003, the rate of autism has not decreased as would be expected if it had been the causative agent.
291:
The term "life-threatening" in the context of a serious adverse event refers to an event in which the patient was at risk of death at the time of the event; it does not refer to an event which hypothetically might have caused death if it were more severe.
2932:
2917:
3406:
2049:
Kraus MR, Schäfer A, Schöttker K, Keicher C, Weissbrich B, Hofbauer I, Scheurlen M (April 2008). "Therapy of interferon-induced depression in chronic hepatitis C with citalopram: a randomised, double-blind, placebo-controlled study".
511:. They can be reversible or irreversible, and a compromise must be found by the physician and the patient between the beneficial or life-saving consequences of surgery versus its adverse effects. For example, a limb may be lost to
320:
and meta-analyses of therapeutic interventions often unknowingly overemphasise health benefit. To balance the overemphasis on benefit, scholars have called for more complete reporting of harm from clinical trials.
454:
MHPD also works closely with international organizations to facilitate the sharing of information. Adverse reaction reporting is mandatory for the industry and voluntary for consumers and health professionals.
316:. Research suggests that these events are often inadequately reported in publicly available reports. Because of the lack of these data and uncertainty about methods for synthesising them, individuals conducting
184:
is similar to adverse effect, but the latter is typically used in pharmacological contexts, or when the negative effect is expected or common. If the negative effect results from an unsuitable or incorrect
791:
Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects, which have a widely variable incidence according to individual sensitivity, include
442:
reports and provides New
Zealand-specific information on adverse reactions to these products, and serves to support clinical decision making when unusual symptoms are thought to be therapy related
1469:"Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013"
3267:
288:
is considered a serious adverse event. The results of trials are often included in the labelling of the medication to provide information both for patients and the prescribing physicians.
248:
reported by a patient. Adverse effects may cause a reversible or irreversible change, including an increase or decrease in the susceptibility of the individual to other chemicals,
1572:
Expert working group (efficacy) of the international conference on harmonization of technical requirements for registration of pharmaceuticals for human use (August 25, 2007).
338:
3172:
1519:
Expert
Working Group (Efficacy) of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (March 1995).
3975:
2161:
1925:
1299:
2790:
3260:
3124:
1446:
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398:
820:, dry mouth, etc. These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.
2575:
Reid R (December 2010). "SOGC clinical practice guideline. No. 252, December 2010. Oral contraceptives and the risk of venous thromboembolism: an update".
2690:
Fialip J, Aumaitre O, Eschalier A, Maradeix B, Dordain G, Lavarenne J (December 1987). "Benzodiazepine withdrawal seizures: analysis of 48 case reports".
2382:
2821:
2325:
1259:, which led to class actions brought by tens of thousands of plaintiffs against manufacturers of gel-based implants, due to allegations of damage to the
727:
The scientific field of activity associated with drug safety is increasingly government-regulated, and is of major concern for the public, as well as to
201:/treatment. Some adverse effects occur only when starting, increasing or discontinuing a treatment. Using a drug or other medical intervention which is
361:
and unlicensed medicines found in cosmetic treatments. Adverse drug reactions (ADRs) can be reported by a number of health care professionals including
827:) warns that people with dementia are more likely to experience adverse effects, and that they are less likely to be able to reliably report symptoms.
414:
2996:– MedWatch lists safety alerts for drugs, biologics, devices and dietary supplements, recalls, market withdrawals, public health advisories and links
1687:, O'Neill RT, Altman DG, Schulz K, Moher D (November 2004). "Better reporting of harms in randomized trials: an extension of the CONSORT statement".
451:
monitoring practices with regards to assessment of signals and safety trends, and risk communications concerning regulated marketed health products.
3253:
3233:
3177:
2734:
1271:
3037:
2093:
1199:
390:
1857:
1810:"Medication appropriateness tool for co-morbid health conditions in dementia: consensus recommendations from a multidisciplinary expert panel"
3968:
3426:
393:(VAERS), the Manufacturer and User Facility Device Experience Database (MAUDE) and the Special Nutritionals Adverse Event Monitoring System.
1550:
418:
1955:
1263:
which have not yet been conclusively proven. In 1998, Dow
Corning settled its remaining suits for $ 3.2 Billion and went into bankruptcy.
221:
with a treatment regimen. Adverse effects of medical treatment resulted in 142,000 deaths in 2013 up from 94,000 deaths in 1990 globally.
2877:
2351:
4186:
3743:
3431:
854:(Cytotec), a labor-inducing drug (this is a case where the adverse effect has been used legally and illegally for performing abortions)
3536:
3005:
2668:
713:
119:
2230:
3961:
3529:
2983:
2471:
Patten SB, Neutel CI (February 2000). "Corticosteroid-induced adverse psychiatric effects: incidence, diagnosis and management".
1325:
1123:
342:
2299:
2445:
731:. The distinction between adverse and nonadverse effects is a major undertaking when a new drug is developed and tested before
53:
2523:
1977:
4176:
2843:
100:
57:
1917:
425:
program is tasked with acting on this reporting to reduce and minimize the number of preventable adverse effects each year.
1278:, have led to public outcry and changes in medical therapy, although its benefits largely surpassed the statistical risks.
72:
4110:
3556:
3167:
2756:
2131:
1895:
1524:
2553:
2153:
1580:
1225:
Sometimes, putative medical adverse effects are regarded as controversial and generate heated discussions in society and
4171:
4090:
3753:
3562:
2786:
594:
520:
3002:
National
Library of Medicine (Medline Plus, useful lists of conventional drug and medical device articles and websites)
1597:
Ioannidis JP, Lau J (2001). "Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas".
631:
Adverse effects can occur as a collateral or side effect of many interventions, but they are particularly important in
3401:
3203:
3198:
3009:
1402:
670:
and mortality around the world. Drug-drug and food-drug interactions may occur, and so-called "natural drugs" used in
79:
4150:
3867:
3030:
2321:
46:
4035:
3638:
3546:
3451:
3441:
3344:
2972:
2969:– includes a glossary and articles on adverse effects, drug reactions, medical error, iatrogenesis, among others.
2252:
Tripathi RC, Parapuram SK, Tripathi BJ, Zhong Y, Chalam KV (December 1999). "Corticosteroids and glaucoma risk".
1274:, which may affect millions of users, even marginal probabilities of adverse effects of a severe nature, such as
687:
475:, death is a very likely outcome and whether the drug is the cause or a bystander is often difficult to discern.
471:
may be caused by the underlying disease or may be an adverse effect of the treatment. In patients with end-stage
86:
3820:
3436:
3421:
3351:
3329:
3150:
2947:
2374:
732:
467:
Part of the difficulty is identifying the source of a complaint. A headache in a patient taking medication for
422:
1521:"Guideline for Industry – Clinical safety data management: definitions and standards for expedited reporting"
4181:
4120:
3984:
3748:
3339:
3078:
1355:
1330:
1320:
1230:
785:
728:
181:
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3835:
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3524:
3381:
3145:
1730:
Bailey, C; Peddie, D; Wickham, ME; Badke, K; Small, SS; Doyle-Waters, MM; Balka, E; Hohl, CM (July 2016).
1267:
1119:
961:
769:
721:
598:
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3758:
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for sale to the public. Investigators in human clinical trials are obligated to report these events in
2999:
4191:
4065:
3917:
3905:
3785:
1684:
1340:
1168:
981:
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675:
671:
640:
571:
and local reactions in the vaccination site. Very rarely, there is a serious adverse effect, such as
524:
2101:
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244:
change detected at the microscopic, macroscopic or physiological level. It may also be indicated by
4040:
4005:
3929:
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3780:
3733:
3607:
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2844:"Silicone Breast Implants in Relation to Connective Tissue Diseases and Immunologic Dysfunction"
1542:
1947:
1640:
Chou R, Helfand M (June 2005). "Challenges in systematic reviews that assess treatment harms".
4115:
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3805:
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3472:
3208:
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350:
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and elimination of many drugs, so patients taking it are likely to experience a reduction in
464:
may not include long-term and subtle effects that may ultimately be attributed to a therapy.
4140:
4050:
4010:
3800:
3654:
3371:
2699:
2623:
2612:"Sildenafil citrate ingestion and prolonged priapism and tachycardia in a pediatric patient"
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2480:
2417:
2261:
2192:
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2015:
1829:
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may have adverse effects due to the nature of its biological preparation, sometimes using
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4055:
1171:
use. Some antihistamines are used in sleep aids explicitly because they cause drowsiness.
17:
2226:
1780:"MATCH-D Medication Appropriateness Tool for Comorbid Health conditions during Dementia"
1266:
Due to the exceedingly high impact on public health of widely used medications, such as
4085:
4070:
3597:
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3277:
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2019:
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386:
300:
In many countries, adverse effects are required by law to be reported, researched in
273:
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2449:
2281:
2212:
2079:
2035:
1716:
1669:
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2406:"Lactic acidosis associated with stavudine administration: a report of five cases"
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4130:
4030:
3659:
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3324:
3093:
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1229:
against drug manufacturers. One example is the recent controversy as to whether
1145:
1106:
994:
883:
851:
840:
823:
The
Medication Appropriateness Tool for Comorbid Health Conditions in Dementia (
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519:, but the patient's life is saved. Presently, one of the greatest advantages of
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575:, a severe, sometimes fatal complication which may result in persons who have
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Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy
2196:
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Page AT, Potter K, Clifford R, McLachlan AJ, Etherton-Beer C (October 2016).
1426:
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procedures may also have adverse effects, depending much on whether they are
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and not an adverse effect. Adverse effects are sometimes referred to as "
2909:
1574:"Guideline for Industry Structure and Content of Clinical Study Reports"
27:
Harmful effect resulting from a medication or other medical intervention
3669:
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1111:
896:
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488:
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225:
210:
169:
165:
2183:
Tapiainen T, Heininger U (June 2005). "Fever following immunization".
1825:
1747:
1543:"Reporting Serious Problems to FDA - What is a Serious Adverse Event?"
784:, and a significant number of deaths, causing the forced or voluntary
655:, so they may be avoided or decreased by means of careful and precise
433:
Adverse reaction reporting is an important component of New
Zealand's
4080:
2921:
1345:
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1141:
1024:
1016:
844:
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773:
706:
694:
576:
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Mokrzycki MH, Harris C, May H, Laut J, Palmisano J (January 2000).
438:
1102:
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990:
930:
702:
564:
560:
370:
229:
1467:
349:. This includes all licensed medicines, from medicines issued on
209:
of adverse effects. Adverse effects may cause complications of a
3298:
2229:. Centers for Disease Control and Prevention (CDC). 2018-07-12.
1403:"Adverse drug reactions: definitions, diagnosis, and management"
635:, due to its wider, and sometimes uncontrollable, use by way of
539:
535:
504:
309:
249:
224:
The harmful outcome is usually indicated by some result such as
206:
3957:
3249:
3019:
3015:
1083:
764:(Vioxx), where drastic adverse effects were observed, such as
717:
530:
Other nonsurgical physical procedures, such as high-intensity
29:
2978:
2661:"How do you know if you have rhabdomyolysis from statin use?"
2296:"Chemotherapy and hair loss: What to expect during treatment"
1779:
674:
can have dangerous adverse effects. For example, extracts of
542:. In general, these therapies try to avoid damage to healthy
491:
may have a number of undesirable or harmful effects, such as
280:. Generally, any event which causes death, permanent damage,
705:
levels of drugs they are taking for other purposes, such as
1732:"Adverse drug event reporting systems: a systematic review"
2966:
2006:
Bray RJ (1998). "Propofol infusion syndrome in children".
339:
Medicines and
Healthcare products Regulatory Agency (MHRA)
1918:"Even Low Dose of Aspirin Can Cause Intestinal Bleeding"
643:
becomes an important issue here. Adverse effects, like
389:
several reporting systems have been built, such as the
304:
and included into the patient information accompanying
1888:"Morphine Addiction Withdrawal Symptoms and Treatment"
2375:"What Are the Side Effects of Adults Taking Ritalin?"
1401:
Edwards, I. Ralph; Aronson, Jeffrey K. (2000-10-07).
1252:
Another instance is the potential adverse effects of
2899:
3720:
3692:
3647:
3616:
3590:
3574:
3490:
3465:
3394:
3317:
3291:
3284:
3222:
3186:
3133:
3102:
3051:
2903:
142:
137:
60:. Unsourced material may be challenged and removed.
3173:Political abuse of psychiatry in the United States
2322:"Headache After an Epidural or Spinal Anaesthetic"
413:,adverse effect reporting is administered by the
357:from a supermarket. The scheme also includes all
2610:Wills BK, Albinson C, Wahl M, Clifton J (2007).
2154:"Can anti-depressants cause sexual dysfunction?"
1300:Classification of Pharmaco-Therapeutic Referrals
160:is an undesired harmful effect resulting from a
1654:10.7326/0003-4819-142-12_part_2-200506211-00009
1579:. FDA Center for Drug Evaluation and Research.
1523:. FDA Center for Drug Evaluation and Research.
1194:, increased tendency associated to the use of
439:Centre for Adverse Reactions Monitoring (CARM)
397:is the main reporting center, operated by the
3969:
3261:
3125:Prescription drug prices in the United States
3031:
8:
2577:Journal of Obstetrics and Gynaecology Canada
2124:"Xenical and Diarrhea: a study of 591 users"
345:to gather information on adverse effects to
176:", when judged to be secondary to a main or
2789:. U.S. Food and Drug Administration (FDA).
1858:"Mifepristone and Misoprostol for Abortion"
1118:associated with use of estrogen-containing
3976:
3962:
3954:
3912:
3288:
3268:
3254:
3246:
3038:
3024:
3016:
2973:Australian Adverse Drug Reactions Bulletin
2900:
134:
2757:"Metoclopramide & Tardive Dyskinesia"
2627:
2421:
1833:
1755:
1492:
546:while maximizing the therapeutic effect.
415:Adverse Drug Reactions Advisory Committee
120:Learn how and when to remove this message
1736:British Journal of Clinical Pharmacology
1701:10.7326/0003-4819-141-10-200411160-00009
1050:users, which prompted FDA to remove the
507:, loss of function, or changes in local
3178:Political abuse of psychiatry in Russia
2134:from the original on September 20, 2011
1393:
527:, is the reduction of adverse effects.
213:or procedure and negatively affect its
2737:from the original on December 28, 2023
2385:from the original on February 18, 2013
1514:
1512:
1200:selective serotonin reuptake inhibitor
690:are known to cause an increase in the
662:Adverse effects may also be caused by
391:Vaccine Adverse Event Reporting System
3427:Radiation-induced erythema multiforme
2446:"Metformin and Fatal Lactic Acidosis"
2348:"Ephedra (Ephedra sinica) / ma huang"
2302:from the original on February 5, 2013
2227:"Possible Side-effects from Vaccines"
172:. An adverse effect may be termed a "
7:
3900:
3006:When Medicine Hurts Instead of Helps
2870:"Breast Implant Litigation Timeline"
2793:from the original on January 6, 2013
1553:from the original on 25 January 2018
984:associated with many drugs, such as
419:Australian Drug Evaluation Committee
58:adding citations to reliable sources
3744:Pseudoverrucous papules and nodules
3432:Radiation-induced hypertrophic scar
2824:from the original on March 20, 2013
2556:from the original on March 27, 2013
2233:from the original on March 17, 2017
2164:from the original on March 21, 2013
1928:from the original on April 20, 2013
1898:from the original on March 18, 2013
343:Commission on Human Medicines (CHM)
272:, a distinction is made between an
2994:Medical Product Safety Information
2659:Behrenbeck T (December 14, 2012).
2526:from the original on June 26, 2015
2350:. Mayo Clinic. September 1, 2012.
2094:"Diabetes and Antipsychotic Drugs"
1586:from the original on May 25, 2009.
1530:from the original on May 11, 2009.
831:Examples with specific medications
197:" because they are generated by a
25:
2988:U.S. Food and Drug Administration
2671:from the original on June 1, 2013
2354:from the original on May 12, 2013
2328:from the original on June 8, 2015
1958:from the original on May 30, 2013
1245:-based preservative used in some
613:may cause the perforation of the
3935:
3923:
3911:
3899:
3888:
3887:
3530:Inner ear decompression sickness
2979:MedEffect Canada (Health Canada)
2704:10.1097/00002826-198712000-00005
2485:10.2165/00002018-200022020-00004
2266:10.2165/00002512-199915060-00004
2020:10.1046/j.1460-9592.1998.00282.x
1326:List of pharmaceutical companies
1124:combined oral contraceptive pill
563:. Common adverse effects may be
34:
3924:
3103:Economic and financial concerns
2880:from the original on 2018-06-20
2814:"CDC sees autism rate rise 25%"
1790:from the original on 2019-05-18
1449:from the original on 2012-03-07
417:(ADRAC), a subcommittee of the
189:or procedure, this is called a
45:needs additional citations for
2298:. Mayo Clinic. March 6, 2012.
1:
4111:Rebound effect (conservation)
3764:environmental skin conditions
3557:High-altitude pulmonary edema
3168:Political abuse of psychiatry
2812:Jaslow, R. (March 29, 2012).
2589:10.1016/S1701-2163(16)34746-6
2514:Willacy H (January 4, 2013).
1982:Gentamicin Information Center
1485:10.1016/S0140-6736(14)61682-2
1419:10.1016/S0140-6736(00)02799-9
788:of the drug from the market.
651:or drug levels at the target
609:materials often occur, and a
4091:Parable of the broken window
3754:Tropical anhidrotic asthenia
3563:High-altitude cerebral edema
2410:Clinical Infectious Diseases
2373:Bergeson, B. (May 6, 2010).
1541:Office of the Commissioner.
744:disasters, such as those of
647:of drugs, are a function of
399:Food and Drug Administration
240:, loss of function, or as a
3776:frictional/traumatic/sports
3402:Chronic radiation keratosis
3204:Hospital-acquired infection
3199:Hospital-acquired pneumonia
3010:Alliance for Aging Research
1689:Annals of Internal Medicine
1642:Annals of Internal Medicine
1272:hormone replacement therapy
1131:associated with the use of
1078:associated with the use of
4208:
4187:Effects of external causes
4151:Tyranny of small decisions
3868:Pseudoacanthosis nigricans
3008:– June 1998 report by the
2725:Kenny T (April 20, 2011).
2692:Clinical Neuropharmacology
1154:caused by withdrawal from
624:
4036:Excess burden of taxation
3991:
3883:
3639:Space adaptation syndrome
3547:Chronic mountain sickness
3452:Radiation recall reaction
3442:Radiation-induced morphea
3345:Warm water immersion foot
2761:Tardive Dyskinesia Center
2629:10.1080/15563650701664483
2185:Expert Review of Vaccines
1952:Weitz & Luxenberg P.C
1814:Internal Medicine Journal
1185:(Viagra), when used with
964:medications (neuroleptic
252:, or procedures, such as
18:Adverse effect (medicine)
3821:Weathering nodule of ear
3437:Radiation-induced keloid
3422:Radiation-induced cancer
3352:Non-freezing cold injury
3330:Immersion foot syndromes
3151:Compulsory sterilization
2787:"Thimerosal in Vaccines"
2197:10.1586/14760584.4.3.419
1948:"Coronary Heart Disease"
1683:Ioannidis JP, Evans SJ,
905:disease associated with
423:Quality Use of Medicines
217:. They may also lead to
4121:Self-defeating prophecy
3985:Unintended consequences
3749:Sclerosing lymphangitis
3340:Tropical immersion foot
3079:Unnecessary health care
2516:"Paracetamol Poisoning"
2064:10.1136/gut.2007.131607
1356:Perioperative mortality
1331:List of withdrawn drugs
1321:Evidence-based medicine
1208:associated with use of
756:and, more recently, of
722:hormonal contraceptives
686:used for treating mild
538:and alterations in the
515:in case of untreatable
4146:Tragedy of the commons
3836:Painful fat herniation
3816:Vibration white finger
3525:Decompression sickness
3382:Erythrocyanosis crurum
3146:Sluggish schizophrenia
3000:Medical Devices Safety
2967:Patient Safety Network
1611:10.1001/jama.285.4.437
1268:hormonal contraception
1202:(SSRI) antidepressants
1120:hormonal contraception
1064:caused by stimulants,
962:atypical antipsychotic
770:pulmonary hypertension
760:(Baycol, Lipobay) and
337:initiative run by the
314:clinical study reports
4177:Clinical pharmacology
4096:Paradox of enrichment
3791:Fissure of the nipple
3759:UV-sensitive syndrome
3684:Adverse drug reaction
3513:Middle ear barotrauma
3503:Arterial gas embolism
3223:Records and histories
3194:Adverse drug reaction
3162:The Protest Psychosis
2975:– published bimonthly
1306:Consultant pharmacist
1289:Adverse drug reaction
974:caused by the use of
627:Adverse drug reaction
278:serious adverse event
4066:Inverse consequences
3786:Equestrian perniosis
2008:Pediatric Anesthesia
1924:. November 9, 2000.
1341:Medical prescription
982:Erectile dysfunction
937:, in children using
735:it. This is done in
697:responsible for the
680:Hypericum perforatum
672:alternative medicine
641:responsible drug use
525:laparoscopic surgery
353:to medicines bought
54:improve this article
4172:Medical terminology
4041:Four Pests campaign
3873:Narcotic dermopathy
3781:Black heel and palm
3734:Dermatosis neglecta
3608:Psychological abuse
3447:Radiation poisoning
3064:Medical malpractice
2616:Clinical Toxicology
1648:(12 Pt 2): 1090–9.
1413:(9237): 1255–1259.
714:protease inhibitors
645:therapeutic effects
4126:Self-refuting idea
4106:Perverse incentive
3843:Uranium dermatosis
3796:Pulling boat hands
3705:Lightning injuries
3120:Financial toxicity
2546:"What is Melasma?"
1784:www.match-d.com.au
1371:Pleiotropy (drugs)
1361:Pharmacotoxicology
1233:was linked to the
1206:Tardive dyskinesia
1052:dietary supplement
1039:spinal anaesthesia
740:sometimes lead to
729:drug manufacturers
595:minimally invasive
521:minimally invasive
484:Medical procedures
359:herbal supplements
331:Yellow Card Scheme
318:systematic reviews
178:therapeutic effect
4159:
4158:
4116:Risk compensation
3951:
3950:
3700:Electrical injury
3542:Altitude sickness
3390:
3389:
3243:
3242:
3209:Iatrogenic anemia
3156:Physician gag law
2984:Medication Errors
2962:
2961:
2767:on March 23, 2013
2583:(12): 1192–1197.
2254:Drugs & Aging
2104:on April 11, 2013
1868:on March 30, 2013
1826:10.1111/imj.13215
1820:(10): 1189–1197.
1748:10.1111/bcp.12944
1336:Medical algorithm
1019:may be caused by
573:eczema vaccinatum
532:radiation therapy
523:surgery, such as
435:pharmacovigilance
296:Reporting systems
254:drug interactions
205:may increase the
154:
153:
132:Medical condition
130:
129:
122:
104:
16:(Redirected from
4199:
4141:Streisand effect
4051:Hawthorne effect
4011:Butterfly effect
4006:Braess's paradox
3978:
3971:
3964:
3955:
3939:
3927:
3926:
3915:
3914:
3903:
3902:
3891:
3890:
3727:physical factors
3723:skin conditions
3655:Hypersensitivity
3372:Cold intolerance
3289:
3276:Consequences of
3270:
3263:
3256:
3247:
3187:Related concerns
3040:
3033:
3026:
3017:
2901:
2889:
2888:
2886:
2885:
2866:
2860:
2859:
2857:
2855:
2846:. Archived from
2840:
2834:
2833:
2831:
2829:
2809:
2803:
2802:
2800:
2798:
2783:
2777:
2776:
2774:
2772:
2763:. Archived from
2753:
2747:
2746:
2744:
2742:
2727:"Antihistamines"
2722:
2716:
2715:
2687:
2681:
2680:
2678:
2676:
2656:
2650:
2649:
2631:
2607:
2601:
2600:
2572:
2566:
2565:
2563:
2561:
2542:
2536:
2535:
2533:
2531:
2511:
2505:
2504:
2468:
2462:
2461:
2459:
2457:
2452:on April 5, 2013
2448:. Archived from
2442:
2436:
2435:
2425:
2401:
2395:
2394:
2392:
2390:
2370:
2364:
2363:
2361:
2359:
2344:
2338:
2337:
2335:
2333:
2318:
2312:
2311:
2309:
2307:
2292:
2286:
2285:
2249:
2243:
2242:
2240:
2238:
2223:
2217:
2216:
2180:
2174:
2173:
2171:
2169:
2160:. May 15, 2011.
2150:
2144:
2143:
2141:
2139:
2120:
2114:
2113:
2111:
2109:
2100:. Archived from
2090:
2084:
2083:
2046:
2040:
2039:
2003:
1997:
1996:
1994:
1993:
1984:. Archived from
1974:
1968:
1967:
1965:
1963:
1944:
1938:
1937:
1935:
1933:
1914:
1908:
1907:
1905:
1903:
1884:
1878:
1877:
1875:
1873:
1864:. Archived from
1854:
1848:
1847:
1837:
1805:
1799:
1798:
1796:
1795:
1776:
1770:
1769:
1759:
1727:
1721:
1720:
1680:
1674:
1673:
1637:
1631:
1630:
1594:
1588:
1587:
1585:
1578:
1569:
1563:
1562:
1560:
1558:
1538:
1532:
1531:
1529:
1516:
1507:
1506:
1496:
1479:(9963): 117–71.
1464:
1458:
1457:
1455:
1454:
1398:
1311:Drug interaction
1181:associated with
1140:associated with
1002:associated with
993:associated with
919:associated with
907:COX-2 inhibitors
895:associated with
882:associated with
850:associated with
710:chemotherapeutic
664:drug interaction
657:pharmacokinetics
437:activities. The
355:over the counter
232:, alteration in
135:
125:
118:
114:
111:
105:
103:
69:"Adverse effect"
62:
38:
30:
21:
4207:
4206:
4202:
4201:
4200:
4198:
4197:
4196:
4162:
4161:
4160:
4155:
4101:Parkinson's law
3996:Abilene paradox
3987:
3982:
3952:
3947:
3879:
3769:Electrical burn
3726:
3725:resulting from
3724:
3722:
3716:
3688:
3675:Arthus reaction
3643:
3624:Motion sickness
3612:
3586:
3570:
3486:
3482:Oxygen toxicity
3461:
3386:
3313:
3280:
3278:external causes
3274:
3244:
3239:
3218:
3182:
3134:Political abuse
3129:
3115:Balance billing
3098:
3047:
3044:
2963:
2958:
2957:
2912:
2898:
2893:
2892:
2883:
2881:
2868:
2867:
2863:
2853:
2851:
2842:
2841:
2837:
2827:
2825:
2811:
2810:
2806:
2796:
2794:
2785:
2784:
2780:
2770:
2768:
2755:
2754:
2750:
2740:
2738:
2724:
2723:
2719:
2689:
2688:
2684:
2674:
2672:
2658:
2657:
2653:
2609:
2608:
2604:
2574:
2573:
2569:
2559:
2557:
2544:
2543:
2539:
2529:
2527:
2513:
2512:
2508:
2470:
2469:
2465:
2455:
2453:
2444:
2443:
2439:
2403:
2402:
2398:
2388:
2386:
2372:
2371:
2367:
2357:
2355:
2346:
2345:
2341:
2331:
2329:
2320:
2319:
2315:
2305:
2303:
2294:
2293:
2289:
2251:
2250:
2246:
2236:
2234:
2225:
2224:
2220:
2182:
2181:
2177:
2167:
2165:
2152:
2151:
2147:
2137:
2135:
2122:
2121:
2117:
2107:
2105:
2092:
2091:
2087:
2048:
2047:
2043:
2005:
2004:
2000:
1991:
1989:
1978:"Kidney Damage"
1976:
1975:
1971:
1961:
1959:
1946:
1945:
1941:
1931:
1929:
1916:
1915:
1911:
1901:
1899:
1886:
1885:
1881:
1871:
1869:
1856:
1855:
1851:
1807:
1806:
1802:
1793:
1791:
1778:
1777:
1773:
1729:
1728:
1724:
1682:
1681:
1677:
1639:
1638:
1634:
1596:
1595:
1591:
1583:
1576:
1571:
1570:
1566:
1556:
1554:
1540:
1539:
1535:
1527:
1518:
1517:
1510:
1466:
1465:
1461:
1452:
1450:
1400:
1399:
1395:
1390:
1385:
1284:
1257:breast implants
1223:
1163:or increase in
1156:benzodiazepines
1098:corticosteroids
1076:Lactic acidosis
1066:methylphenidate
986:antidepressants
833:
748:(the so-called
692:cytochrome P450
637:self-medication
629:
623:
601:. For example,
486:
481:
461:
448:
431:
407:
383:
327:
306:medical devices
302:clinical trials
298:
286:hospitalization
270:clinical trials
262:
203:contraindicated
133:
126:
115:
109:
106:
63:
61:
51:
39:
28:
23:
22:
15:
12:
11:
5:
4205:
4203:
4195:
4194:
4189:
4184:
4182:Patient safety
4179:
4174:
4164:
4163:
4157:
4156:
4154:
4153:
4148:
4143:
4138:
4133:
4128:
4123:
4118:
4113:
4108:
4103:
4098:
4093:
4088:
4086:Osborne effect
4083:
4078:
4073:
4071:Jevons paradox
4068:
4063:
4058:
4053:
4048:
4046:Goodhart's law
4043:
4038:
4033:
4028:
4023:
4018:
4016:Campbell's law
4013:
4008:
4003:
4001:Adverse effect
3998:
3992:
3989:
3988:
3983:
3981:
3980:
3973:
3966:
3958:
3949:
3948:
3946:
3945:
3933:
3921:
3909:
3897:
3884:
3881:
3880:
3878:
3877:
3876:
3875:
3870:
3865:
3860:
3855:
3845:
3840:
3839:
3838:
3833:
3828:
3826:Wrestler's ear
3823:
3818:
3813:
3808:
3806:Surfer's knots
3803:
3798:
3793:
3788:
3783:
3773:
3772:
3771:
3761:
3756:
3751:
3746:
3741:
3736:
3730:
3728:
3718:
3717:
3715:
3714:
3709:
3708:
3707:
3696:
3694:
3690:
3689:
3687:
3686:
3680:
3679:
3678:
3677:
3672:
3667:
3662:
3651:
3649:
3648:Adverse effect
3645:
3644:
3642:
3641:
3636:
3631:
3626:
3620:
3618:
3614:
3613:
3611:
3610:
3605:
3600:
3598:Physical abuse
3594:
3592:
3588:
3587:
3585:
3584:
3578:
3576:
3572:
3571:
3569:
3568:
3567:
3566:
3560:
3554:
3549:
3544:
3534:
3533:
3532:
3522:
3521:
3520:
3515:
3510:
3505:
3494:
3492:
3488:
3487:
3485:
3484:
3479:
3469:
3467:
3463:
3462:
3460:
3459:
3454:
3449:
3444:
3439:
3434:
3429:
3424:
3419:
3417:Radiation burn
3414:
3412:Radiation acne
3409:
3404:
3398:
3396:
3392:
3391:
3388:
3387:
3385:
3384:
3379:
3374:
3369:
3364:
3359:
3354:
3349:
3348:
3347:
3342:
3337:
3327:
3321:
3319:
3315:
3314:
3312:
3311:
3306:
3301:
3295:
3293:
3286:
3282:
3281:
3275:
3273:
3272:
3265:
3258:
3250:
3241:
3240:
3238:
3237:
3230:Drug pollution
3226:
3224:
3220:
3219:
3217:
3216:
3211:
3206:
3201:
3196:
3190:
3188:
3184:
3183:
3181:
3180:
3175:
3170:
3165:
3158:
3153:
3148:
3143:
3137:
3135:
3131:
3130:
3128:
3127:
3122:
3117:
3112:
3106:
3104:
3100:
3099:
3097:
3096:
3091:
3086:
3084:Adverse effect
3081:
3076:
3074:Patient safety
3071:
3066:
3061:
3055:
3053:
3049:
3048:
3045:
3043:
3042:
3035:
3028:
3020:
3014:
3013:
3003:
2997:
2991:
2981:
2976:
2970:
2960:
2959:
2956:
2955:
2944:
2929:
2913:
2908:
2907:
2905:
2904:Classification
2897:
2896:External links
2894:
2891:
2890:
2861:
2835:
2804:
2778:
2748:
2717:
2682:
2651:
2622:(7): 798–800.
2602:
2567:
2537:
2506:
2463:
2437:
2423:10.1086/313594
2416:(1): 198–200.
2396:
2365:
2339:
2313:
2287:
2244:
2218:
2175:
2145:
2115:
2085:
2041:
1998:
1969:
1939:
1909:
1879:
1849:
1800:
1771:
1722:
1675:
1632:
1589:
1564:
1533:
1508:
1459:
1392:
1391:
1389:
1386:
1384:
1383:
1378:
1373:
1368:
1363:
1358:
1353:
1351:Patient safety
1348:
1343:
1338:
1333:
1328:
1323:
1318:
1316:EudraVigilance
1313:
1308:
1303:
1296:
1291:
1285:
1283:
1280:
1222:
1219:
1218:
1217:
1210:metoclopramide
1203:
1189:
1172:
1158:
1149:
1138:Rhabdomyolysis
1135:
1126:
1122:, such as the
1109:
1100:
1091:
1090:(for diabetes)
1073:
1059:
1041:
1032:
1010:
1004:corticosteroid
997:
988:
979:
969:
955:
949:hepatic injury
942:
928:
917:kidney failure
910:
903:Cardiovascular
900:
886:
877:
855:
832:
829:
676:St John's wort
625:Main article:
622:
619:
485:
482:
480:
477:
460:
457:
447:
444:
430:
427:
406:
403:
382:
379:
335:United Kingdom
326:
325:United Kingdom
323:
297:
294:
284:, or requires
261:
260:Classification
258:
219:non-compliance
158:adverse effect
152:
151:
146:
140:
139:
138:Adverse effect
131:
128:
127:
42:
40:
33:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4204:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4169:
4167:
4152:
4149:
4147:
4144:
4142:
4139:
4137:
4134:
4132:
4129:
4127:
4124:
4122:
4119:
4117:
4114:
4112:
4109:
4107:
4104:
4102:
4099:
4097:
4094:
4092:
4089:
4087:
4084:
4082:
4079:
4077:
4074:
4072:
4069:
4067:
4064:
4062:
4059:
4057:
4054:
4052:
4049:
4047:
4044:
4042:
4039:
4037:
4034:
4032:
4029:
4027:
4024:
4022:
4019:
4017:
4014:
4012:
4009:
4007:
4004:
4002:
3999:
3997:
3994:
3993:
3990:
3986:
3979:
3974:
3972:
3967:
3965:
3960:
3959:
3956:
3944:
3943:
3938:
3934:
3932:
3931:
3922:
3920:
3919:
3910:
3908:
3907:
3898:
3896:
3895:
3886:
3885:
3882:
3874:
3871:
3869:
3866:
3864:
3861:
3859:
3856:
3854:
3853:Skin pop scar
3851:
3850:
3849:
3846:
3844:
3841:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3812:
3809:
3807:
3804:
3802:
3801:Runner's rump
3799:
3797:
3794:
3792:
3789:
3787:
3784:
3782:
3779:
3778:
3777:
3774:
3770:
3767:
3766:
3765:
3762:
3760:
3757:
3755:
3752:
3750:
3747:
3745:
3742:
3740:
3737:
3735:
3732:
3731:
3729:
3719:
3713:
3710:
3706:
3703:
3702:
3701:
3698:
3697:
3695:
3691:
3685:
3682:
3681:
3676:
3673:
3671:
3668:
3666:
3663:
3661:
3658:
3657:
3656:
3653:
3652:
3650:
3646:
3640:
3637:
3635:
3632:
3630:
3627:
3625:
3622:
3621:
3619:
3615:
3609:
3606:
3604:
3601:
3599:
3596:
3595:
3593:
3589:
3583:
3580:
3579:
3577:
3573:
3564:
3561:
3558:
3555:
3553:
3550:
3548:
3545:
3543:
3540:
3539:
3538:
3537:High altitude
3535:
3531:
3528:
3527:
3526:
3523:
3519:
3516:
3514:
3511:
3509:
3508:Aerosinusitis
3506:
3504:
3501:
3500:
3499:
3496:
3495:
3493:
3489:
3483:
3480:
3478:
3474:
3471:
3470:
3468:
3464:
3458:
3455:
3453:
3450:
3448:
3445:
3443:
3440:
3438:
3435:
3433:
3430:
3428:
3425:
3423:
3420:
3418:
3415:
3413:
3410:
3408:
3405:
3403:
3400:
3399:
3397:
3393:
3383:
3380:
3378:
3375:
3373:
3370:
3368:
3365:
3363:
3360:
3358:
3355:
3353:
3350:
3346:
3343:
3341:
3338:
3336:
3333:
3332:
3331:
3328:
3326:
3323:
3322:
3320:
3316:
3310:
3307:
3305:
3302:
3300:
3297:
3296:
3294:
3290:
3287:
3283:
3279:
3271:
3266:
3264:
3259:
3257:
3252:
3251:
3248:
3235:
3231:
3228:
3227:
3225:
3221:
3215:
3212:
3210:
3207:
3205:
3202:
3200:
3197:
3195:
3192:
3191:
3189:
3185:
3179:
3176:
3174:
3171:
3169:
3166:
3164:
3163:
3159:
3157:
3154:
3152:
3149:
3147:
3144:
3142:
3139:
3138:
3136:
3132:
3126:
3123:
3121:
3118:
3116:
3113:
3111:
3108:
3107:
3105:
3101:
3095:
3092:
3090:
3089:Patient abuse
3087:
3085:
3082:
3080:
3077:
3075:
3072:
3070:
3069:Medical error
3067:
3065:
3062:
3060:
3057:
3056:
3054:
3050:
3041:
3036:
3034:
3029:
3027:
3022:
3021:
3018:
3011:
3007:
3004:
3001:
2998:
2995:
2992:
2989:
2985:
2982:
2980:
2977:
2974:
2971:
2968:
2965:
2964:
2954:
2950:
2949:
2945:
2943:
2939:
2938:
2934:
2930:
2928:
2924:
2923:
2919:
2915:
2914:
2911:
2906:
2902:
2895:
2879:
2875:
2871:
2865:
2862:
2850:on 2013-03-03
2849:
2845:
2839:
2836:
2823:
2819:
2815:
2808:
2805:
2792:
2788:
2782:
2779:
2766:
2762:
2758:
2752:
2749:
2736:
2732:
2728:
2721:
2718:
2713:
2709:
2705:
2701:
2698:(6): 538–44.
2697:
2693:
2686:
2683:
2670:
2666:
2662:
2655:
2652:
2647:
2643:
2639:
2635:
2630:
2625:
2621:
2617:
2613:
2606:
2603:
2598:
2594:
2590:
2586:
2582:
2578:
2571:
2568:
2555:
2551:
2547:
2541:
2538:
2525:
2521:
2517:
2510:
2507:
2502:
2498:
2494:
2490:
2486:
2482:
2479:(2): 111–22.
2478:
2474:
2467:
2464:
2451:
2447:
2441:
2438:
2433:
2429:
2424:
2419:
2415:
2411:
2407:
2400:
2397:
2384:
2380:
2376:
2369:
2366:
2353:
2349:
2343:
2340:
2327:
2323:
2317:
2314:
2301:
2297:
2291:
2288:
2283:
2279:
2275:
2271:
2267:
2263:
2260:(6): 439–50.
2259:
2255:
2248:
2245:
2232:
2228:
2222:
2219:
2214:
2210:
2206:
2202:
2198:
2194:
2191:(3): 419–27.
2190:
2186:
2179:
2176:
2163:
2159:
2155:
2149:
2146:
2133:
2129:
2125:
2119:
2116:
2103:
2099:
2095:
2089:
2086:
2081:
2077:
2073:
2069:
2065:
2061:
2057:
2053:
2045:
2042:
2037:
2033:
2029:
2025:
2021:
2017:
2013:
2009:
2002:
1999:
1988:on 2013-05-04
1987:
1983:
1979:
1973:
1970:
1957:
1953:
1949:
1943:
1940:
1927:
1923:
1919:
1913:
1910:
1897:
1893:
1889:
1883:
1880:
1867:
1863:
1859:
1853:
1850:
1845:
1841:
1836:
1831:
1827:
1823:
1819:
1815:
1811:
1804:
1801:
1789:
1785:
1781:
1775:
1772:
1767:
1763:
1758:
1753:
1749:
1745:
1741:
1737:
1733:
1726:
1723:
1718:
1714:
1710:
1706:
1702:
1698:
1695:(10): 781–8.
1694:
1690:
1686:
1679:
1676:
1671:
1667:
1663:
1659:
1655:
1651:
1647:
1643:
1636:
1633:
1628:
1624:
1620:
1616:
1612:
1608:
1605:(4): 437–43.
1604:
1600:
1593:
1590:
1582:
1575:
1568:
1565:
1552:
1548:
1544:
1537:
1534:
1526:
1522:
1515:
1513:
1509:
1504:
1500:
1495:
1490:
1486:
1482:
1478:
1474:
1470:
1463:
1460:
1448:
1444:
1440:
1436:
1432:
1428:
1424:
1420:
1416:
1412:
1408:
1404:
1397:
1394:
1387:
1382:
1379:
1377:
1374:
1372:
1369:
1367:
1364:
1362:
1359:
1357:
1354:
1352:
1349:
1347:
1344:
1342:
1339:
1337:
1334:
1332:
1329:
1327:
1324:
1322:
1319:
1317:
1314:
1312:
1309:
1307:
1304:
1302:
1301:
1297:
1295:
1292:
1290:
1287:
1286:
1281:
1279:
1277:
1276:breast cancer
1273:
1269:
1264:
1262:
1261:immune system
1258:
1255:
1250:
1248:
1244:
1240:
1236:
1232:
1228:
1221:Controversies
1220:
1215:
1214:antipsychotic
1211:
1207:
1204:
1201:
1197:
1193:
1190:
1188:
1187:nitroglycerin
1184:
1180:
1176:
1173:
1170:
1169:antihistamine
1166:
1162:
1159:
1157:
1153:
1150:
1147:
1143:
1139:
1136:
1134:
1130:
1127:
1125:
1121:
1117:
1113:
1110:
1108:
1104:
1101:
1099:
1095:
1092:
1089:
1085:
1081:
1077:
1074:
1071:
1067:
1063:
1060:
1057:
1053:
1049:
1045:
1042:
1040:
1036:
1033:
1030:
1026:
1022:
1018:
1014:
1011:
1009:
1005:
1001:
998:
996:
992:
989:
987:
983:
980:
977:
973:
970:
967:
963:
959:
956:
954:
950:
946:
943:
940:
936:
932:
929:
926:
922:
918:
914:
911:
908:
904:
901:
898:
894:
890:
887:
885:
881:
880:Birth defects
878:
875:
871:
867:
863:
859:
856:
853:
849:
846:
842:
838:
835:
834:
830:
828:
826:
821:
819:
815:
811:
807:
803:
799:
795:
789:
787:
783:
779:
778:heart disease
775:
771:
767:
766:teratogenesis
763:
759:
755:
751:
747:
743:
742:public health
738:
734:
730:
725:
723:
719:
715:
711:
708:
704:
700:
696:
693:
689:
685:
684:phytotherapic
681:
677:
673:
669:
665:
660:
658:
654:
650:
646:
642:
638:
634:
628:
620:
618:
616:
612:
608:
607:radiocontrast
605:reactions to
604:
600:
596:
592:
588:
584:
582:
578:
574:
570:
566:
562:
558:
555:
551:
547:
545:
541:
537:
533:
528:
526:
522:
518:
514:
510:
506:
502:
498:
494:
490:
483:
478:
476:
474:
470:
465:
458:
456:
452:
445:
443:
440:
436:
428:
426:
424:
420:
416:
412:
404:
402:
400:
396:
392:
388:
387:United States
381:United States
380:
378:
376:
373:, as well as
372:
368:
364:
360:
356:
352:
348:
344:
340:
336:
332:
324:
322:
319:
315:
311:
307:
303:
295:
293:
289:
287:
283:
282:birth defects
279:
275:
274:adverse event
271:
266:
259:
257:
255:
251:
247:
243:
239:
235:
231:
227:
222:
220:
216:
212:
208:
204:
200:
196:
192:
191:medical error
188:
183:
179:
175:
171:
167:
163:
159:
150:
147:
145:
141:
136:
124:
121:
113:
110:February 2011
102:
99:
95:
92:
88:
85:
81:
78:
74:
71: –
70:
66:
65:Find sources:
59:
55:
49:
48:
43:This article
41:
37:
32:
31:
19:
4076:Murphy's law
4061:Hydra effect
4056:Hutber's law
4021:Cobra effect
4000:
3940:
3928:
3916:
3904:
3892:
3847:
3775:
3763:
3603:Sexual abuse
3591:Maltreatment
3518:Pneumothorax
3377:Acrocyanosis
3367:Aerosol burn
3309:Heat syncope
3304:Hyperthermia
3214:Hand washing
3160:
3141:Drapetomania
3110:Medical debt
3083:
3059:Iatrogenesis
3046:Medical harm
2946:
2931:
2916:
2882:. Retrieved
2873:
2864:
2852:. Retrieved
2848:the original
2838:
2826:. Retrieved
2817:
2807:
2795:. Retrieved
2781:
2769:. Retrieved
2765:the original
2760:
2751:
2739:. Retrieved
2731:Patient.info
2730:
2720:
2695:
2691:
2685:
2673:. Retrieved
2664:
2654:
2619:
2615:
2605:
2580:
2576:
2570:
2558:. Retrieved
2549:
2540:
2528:. Retrieved
2520:Patient.info
2519:
2509:
2476:
2472:
2466:
2454:. Retrieved
2450:the original
2440:
2413:
2409:
2399:
2387:. Retrieved
2378:
2368:
2356:. Retrieved
2342:
2330:. Retrieved
2316:
2304:. Retrieved
2290:
2257:
2253:
2247:
2235:. Retrieved
2221:
2188:
2184:
2178:
2166:. Retrieved
2157:
2148:
2136:. Retrieved
2127:
2118:
2106:. Retrieved
2102:the original
2097:
2088:
2058:(4): 531–6.
2055:
2051:
2044:
2014:(6): 491–9.
2011:
2007:
2001:
1990:. Retrieved
1986:the original
1981:
1972:
1960:. Retrieved
1951:
1942:
1930:. Retrieved
1921:
1912:
1900:. Retrieved
1891:
1882:
1870:. Retrieved
1866:the original
1861:
1852:
1817:
1813:
1803:
1792:. Retrieved
1783:
1774:
1742:(1): 17–29.
1739:
1735:
1725:
1692:
1688:
1678:
1645:
1641:
1635:
1602:
1598:
1592:
1567:
1555:. Retrieved
1546:
1536:
1476:
1472:
1462:
1451:. Retrieved
1410:
1406:
1396:
1376:Polypharmacy
1298:
1265:
1251:
1224:
1179:heart attack
1105:damage from
1086:therapy) or
1082:(Zerit, for
1044:Hypertension
1021:chemotherapy
933:, following
909:(i.e. Vioxx)
822:
790:
758:cerivastatin
746:fenfluramine
726:
679:
661:
633:pharmacology
630:
585:
548:
534:, may cause
529:
501:inflammation
487:
479:By situation
466:
462:
453:
449:
432:
408:
384:
351:prescription
328:
299:
290:
267:
263:
242:pathological
236:, levels of
223:
182:complication
166:intervention
157:
155:
149:Pharmacology
116:
107:
97:
90:
83:
76:
64:
52:Please help
47:verification
44:
4192:Drug safety
4136:Social trap
4131:Serendipity
4031:Externality
3660:Anaphylaxis
3634:Airsickness
3629:Seasickness
3335:Trench foot
3325:Hypothermia
3285:Temperature
3094:Never event
2665:Mayo Clinic
2473:Drug Safety
1685:Gøtzsche PC
1547:www.fda.gov
1235:MMR vaccine
1216:medications
1146:cholesterol
1107:paracetamol
1068:(Ritalin),
995:vaccination
966:psychiatric
884:thalidomide
852:misoprostol
841:miscarriage
754:thalidomide
621:Medications
611:colonoscopy
599:noninvasive
550:Vaccination
459:Limitations
429:New Zealand
367:pharmacists
234:body weight
180:. The term
174:side effect
4166:Categories
4026:CSI effect
3858:Skin track
3811:Tennis toe
3739:Pinch mark
3721:Ungrouped
3665:Angioedema
3582:Starvation
3552:Death zone
3498:Barotrauma
3357:Chilblains
2986:—from the
2953:D000069451
2884:2023-05-20
2379:Livestrong
1992:2013-04-28
1922:WebMD News
1794:2019-06-01
1453:2021-06-01
1407:The Lancet
1388:References
1381:Toxicology
1239:thiomersal
1198:and other
1196:fluoxetine
1183:sildenafil
1161:Drowsiness
1133:sildenafil
1116:thrombosis
1096:caused by
1054:status of
1037:following
960:caused by
953:interferon
951:caused by
945:Depression
941:(Diprivan)
925:antibiotic
921:gentamicin
868:, such as
866:analgesics
848:hemorrhage
818:dermatitis
786:withdrawal
782:neuropathy
752:episode),
699:metabolism
688:depression
615:intestinal
587:Diagnostic
581:dermatitis
579:or atopic
554:attenuated
513:amputation
509:blood flow
497:hemorrhage
363:physicians
195:iatrogenic
168:, such as
162:medication
80:newspapers
3863:Slap mark
3831:Coral cut
3395:Radiation
3362:Frostbite
2874:Frontline
2854:March 16,
2828:March 16,
2797:March 16,
2771:March 20,
2741:March 20,
2675:March 20,
2560:March 20,
2530:March 20,
2456:March 20,
2389:March 20,
2332:March 20,
2306:March 20,
2237:March 20,
2168:March 20,
2138:March 20,
2128:eHealthMe
2108:March 20,
1962:March 20,
1932:March 20,
1902:March 20,
1892:rehabinfo
1872:March 20,
1427:0140-6736
1294:Biosafety
1212:and many
1088:metformin
1080:stavudine
1048:ephedrine
1013:Hair loss
1008:eye drops
978:(Xenical)
893:intestine
862:sedatives
858:Addiction
798:dizziness
762:rofecoxib
733:marketing
668:morbidity
557:pathogens
493:infection
469:influenza
411:Australia
405:Australia
347:medicines
230:mortality
226:morbidity
215:prognosis
199:physician
164:or other
144:Specialty
3918:Glossary
3894:Category
3712:Drowning
3491:Pressure
3477:Asphyxia
3292:Elevated
3052:Concepts
2878:Archived
2822:Archived
2818:CBS News
2791:Archived
2735:Archived
2669:Archived
2638:17952749
2597:21176332
2554:Archived
2550:wiseGEEK
2524:Archived
2501:25933949
2493:10672894
2432:10619755
2383:Archived
2352:Archived
2326:Archived
2300:Archived
2282:22380777
2274:10641955
2231:Archived
2213:20270210
2205:16026253
2162:Archived
2132:Archived
2080:33773564
2072:18079286
2036:39426004
1956:Archived
1926:Archived
1896:Archived
1844:27527376
1788:Archived
1766:27016266
1717:17032571
1709:15545678
1670:22188119
1662:15968034
1627:14529735
1619:11242428
1581:Archived
1557:15 March
1551:Archived
1525:Archived
1503:25530442
1447:Archived
1443:17662080
1435:11072960
1282:See also
1254:silicone
1247:vaccines
1227:lawsuits
1165:appetite
1152:Seizures
1129:Priapism
1070:Adderall
1062:Insomnia
1058:extracts
1035:Headache
1029:leukemia
1023:against
1000:Glaucoma
976:orlistat
972:Diarrhea
958:Diabetes
939:propofol
935:sedation
913:Deafness
889:Bleeding
874:morphine
870:diazepam
860:to many
837:Abortion
814:headache
810:vomiting
802:diarrhea
750:fen-phen
737:toxicity
639:. Thus,
603:allergic
591:invasive
517:gangrene
505:scarring
395:MedWatch
375:patients
341:and the
246:symptoms
3930:Outline
3906:Commons
3670:Allergy
3473:Hypoxia
3457:Sunburn
3318:Reduced
2712:3427560
2646:6629753
2358:May 20,
2098:Medsafe
2028:9836214
1835:5129475
1757:4917803
1494:4340604
1366:Placebo
1243:mercury
1237:(or to
1192:Suicide
1167:due to
1142:statins
1112:Melasma
1056:ephedra
1006:-based
899:therapy
897:aspirin
891:of the
845:uterine
825:MATCH-D
806:malaise
712:drugs,
695:enzymes
569:malaise
544:tissues
489:Surgery
385:In the
238:enzymes
211:disease
170:surgery
94:scholar
4081:Nocebo
3942:Portal
3848:iv use
3617:Travel
3565:(HACE)
3559:(HAPE)
3466:Oxygen
2942:995.89
2710:
2644:
2636:
2595:
2499:
2491:
2430:
2280:
2272:
2211:
2203:
2078:
2070:
2034:
2026:
1842:
1832:
1764:
1754:
1715:
1707:
1668:
1660:
1625:
1617:
1501:
1491:
1473:Lancet
1441:
1433:
1425:
1346:Nocebo
1231:autism
1175:Stroke
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