574:
Johansson, Malin E. V.; Ambort, Daniel; Pelaseyed, Thaher; Schütte, André; Gustafsson, Jenny K.; Ermund, Anna; Subramani, Durai B.; Holmén-Larsson, Jessica M.; Thomsson, Kristina A.; Bergström, Joakim H.; van der Post, Sjoerd; Rodriguez-Piñeiro, Ana M.; Sjövall, Henrik; Bäckström, Malin; Hansson,
299:
have been detected in animals with a wide variety of GI tract anatomy (foregut, hindgut, or simple) and in diet (from herbivores to omnivores and carnivores). It has been found in mammals both wild and domesticated, and in non-mammals like birds, fish and reptiles like the
Burmese python. Mucin
222:, (anaerobic conditions on medium containing gastric mucin). When grown on soft agar mucin medium, colonies appear white with a diameter of 0.7mm. The long axis of single cells is 0.6–1.0 μm. Cells are covered with filaments, and occur singly, in pairs, in short chains and in aggregates.
300:
types, and the glycan types expressed, vary between these organisms, but mucus is a consistent feature of their intestinal tracts. It may be that mucus-colonizing microbes have a role in protecting the host against intestinal pathogens and contribute to restoration of the microbiota.
176:
The genus was named for Antoon DL Akkermans (1940–2006), a Dutch microbiologist recognized for his contribution to microbial ecology, and the epithet from the New Latin and Greek meaning "glycan-loving".
248:. For 72% (1,811) of the coding sequences, a function could be predicted. Genome analysis revealed the presence of many mucin-degrading enzymes, of which a number are predicted to be secreted: 54
770:
632:
Reid, G; Younes, JA; Van der Mei, HC; Gloor, GB; Knight, R; Busscher, HJ (January 2011). "Microbiota restoration: natural and supplemented recovery of human microbial communities".
460:
Ouwerkerk, Janneke P.; van der Ark, Kees C. H.; Davids, Mark; Claassens, Nico J.; Finestra, Teresa Robert; de Vos, Willem M.; Belzer, Clara; Schloss, P. D. (1 December 2016).
783:
757:
411:
Ouwerkerk, Janneke P.; Koehorst, Jasper J.; Schaap, Peter J.; Ritari, Jarmo; Paulin, Lars; Belzer, Clara; de Vos, Willem M. (5 January 2017).
265:
829:
834:
735:
788:
824:
164:
190:
697:
90:
126:
78:
66:
530:
473:
413:"Complete Genome Sequence of Strain Pyt , a Mucin-Degrading Specialist of the Reticulated Python Gut"
249:
269:
233:
Pyt is encoded on a single chromosome of 3,074,121 bp. The G+C content is 57.6% and contains 2,532
657:
614:
253:
199:
31:
796:
649:
606:
556:
499:
442:
388:
347:
54:
801:
641:
596:
588:
546:
538:
489:
481:
432:
424:
378:
337:
320:
Ouwerkerk, Janneke P.; Aalvink, Steven; Belzer, Clara; de Vos, Willem M. (1 November 2016).
226:
367:"List of Bacterial Names with Standing in Nomenclature: a folder available on the Internet"
326:
sp. nov., an anaerobic mucin-degrading bacterium isolated from reticulated python faeces"
218:
as its sole source of carbon and nitrogen. It is culturable under the same conditions as
775:
601:
576:
534:
477:
551:
518:
517:
Costello, Elizabeth K; Gordon, Jeffrey I; Secor, Stephen M; Knight, Rob (3 June 2010).
494:
462:"Adaptation of Akkermansia muciniphila to the Oxic-Anoxic Interface of the Mucus Layer"
461:
437:
412:
818:
661:
257:
234:
195:
618:
720:
729:
210:-forming, oval-shaped bacterium. The typestrain is Pyt (=DSM100705=CIP 110913).
103:
592:
383:
366:
261:
428:
653:
610:
560:
503:
446:
351:
342:
321:
291:-anoxic interface of the intestinal mucin layer. This was demonstrated for
542:
392:
714:
485:
42:
749:
678:
645:
762:
744:
245:
577:"Composition and functional role of the mucus layers in the intestine"
203:
162:-degrading bacterium. It was first isolated from reticulated python (
691:
519:"Postprandial remodeling of the gut microbiota in Burmese pythons"
215:
207:
159:
330:
International
Journal of Systematic and Evolutionary Microbiology
288:
242:
238:
695:
295:
Muc. 16s rRNA gene amplicon sequencing reveals that the genus
704:
371:International Journal of Systematic Bacteriology
406:
404:
402:
315:
313:
8:
692:
264:. The Pyt genome is predicted to encode a
20:
600:
550:
493:
436:
382:
341:
687:- the Bacterial Diversity Metadatabase
309:
466:Applied and Environmental Microbiology
7:
581:Cellular and Molecular Life Sciences
14:
287:This bacterium probably inhabits
575:Gunnar C. (25 September 2011).
268:, indicating the potential for
266:cytochrome bd ubiquinol oxidase
1:
634:Nature Reviews. Microbiology
158:is a species of intestinal
851:
830:Bacteria described in 2016
241:genes, and three complete
593:10.1007/s00018-011-0822-3
384:10.1099/00207713-47-2-590
365:Euzéby, JP (April 1997).
132:
125:
32:Scientific classification
30:
23:
776:akkermansia-glycaniphila
736:Akkermansia glycaniphila
706:Akkermansia glycaniphila
681:Akkermansia glycaniphila
429:10.1128/genomeA.01098-16
324:Akkermansia glycaniphila
181:Biology and biochemistry
165:Malayopython reticulatus
136:Akkermansia glycaniphila
25:Akkermansia glycaniphila
275:The complete genome of
155:Akkermansia glycanphila
835:Gram-negative bacteria
343:10.1099/ijsem.0.001399
543:10.1038/ismej.2010.71
486:10.1128/AEM.01641-16
417:Genome Announcements
279:has been sequenced.
250:glycoside hydrolases
118:A. glycaniphila
16:Species of bacterium
646:10.1038/nrmicro2473
535:2010ISMEJ...4.1375C
478:2016ApEnM..82.6983O
270:aerobic respiration
91:Verrucomicrobiaceae
254:glycosyl hydrolase
79:Verrucomicrobiales
825:Verrucomicrobiota
812:
811:
797:Open Tree of Life
698:Taxon identifiers
587:(22): 3635–3641.
529:(11): 1375–1385.
472:(23): 6983–6993.
336:(11): 4614–4620.
168:) feces in 2016.
151:
150:
55:Verrucomicrobiota
842:
805:
804:
792:
791:
779:
778:
766:
765:
753:
752:
740:
739:
738:
725:
724:
723:
693:
666:
665:
629:
623:
622:
604:
571:
565:
564:
554:
523:The ISME Journal
514:
508:
507:
497:
457:
451:
450:
440:
408:
397:
396:
386:
362:
356:
355:
345:
317:
277:A. glycaniphilia
227:bacterial genome
138:
67:Verrucomicrobiae
21:
850:
849:
845:
844:
843:
841:
840:
839:
815:
814:
813:
808:
800:
795:
787:
782:
774:
769:
761:
756:
748:
743:
734:
733:
728:
719:
718:
713:
700:
679:Type strain of
675:
670:
669:
631:
630:
626:
573:
572:
568:
516:
515:
511:
459:
458:
454:
410:
409:
400:
364:
363:
359:
319:
318:
311:
306:
285:
231:A. glucaniphila
220:A. muciniphilia
214:is able to use
212:A. glycaniphila
186:A. glycaniphila
183:
174:
147:
140:
134:
121:
107:
93:
81:
69:
57:
45:
17:
12:
11:
5:
848:
846:
838:
837:
832:
827:
817:
816:
810:
809:
807:
806:
793:
780:
767:
754:
741:
726:
710:
708:
702:
701:
696:
690:
689:
674:
673:External links
671:
668:
667:
624:
566:
509:
452:
398:
357:
308:
307:
305:
302:
293:A. muciniphila
284:
281:
235:coding regions
191:A. muciniphila
182:
179:
173:
170:
149:
148:
141:
130:
129:
123:
122:
115:
113:
109:
108:
101:
99:
95:
94:
89:
87:
83:
82:
77:
75:
71:
70:
65:
63:
59:
58:
53:
51:
47:
46:
41:
39:
35:
34:
28:
27:
15:
13:
10:
9:
6:
4:
3:
2:
847:
836:
833:
831:
828:
826:
823:
822:
820:
803:
798:
794:
790:
785:
781:
777:
772:
768:
764:
759:
755:
751:
746:
742:
737:
731:
727:
722:
716:
712:
711:
709:
707:
703:
699:
694:
688:
686:
682:
677:
676:
672:
663:
659:
655:
651:
647:
643:
639:
635:
628:
625:
620:
616:
612:
608:
603:
598:
594:
590:
586:
582:
578:
570:
567:
562:
558:
553:
548:
544:
540:
536:
532:
528:
524:
520:
513:
510:
505:
501:
496:
491:
487:
483:
479:
475:
471:
467:
463:
456:
453:
448:
444:
439:
434:
430:
426:
422:
418:
414:
407:
405:
403:
399:
394:
390:
385:
380:
376:
372:
368:
361:
358:
353:
349:
344:
339:
335:
331:
327:
325:
316:
314:
310:
303:
301:
298:
294:
290:
282:
280:
278:
273:
271:
267:
263:
259:
255:
251:
247:
244:
240:
236:
232:
228:
223:
221:
217:
213:
209:
205:
201:
197:
196:Gram-negative
193:
192:
187:
180:
178:
171:
169:
167:
166:
161:
157:
156:
145:
139:
137:
131:
128:
127:Binomial name
124:
120:
119:
114:
111:
110:
106:
105:
100:
97:
96:
92:
88:
85:
84:
80:
76:
73:
72:
68:
64:
61:
60:
56:
52:
49:
48:
44:
40:
37:
36:
33:
29:
26:
22:
19:
705:
684:
680:
640:(1): 27–38.
637:
633:
627:
584:
580:
569:
526:
522:
512:
469:
465:
455:
420:
416:
377:(2): 590–2.
374:
370:
360:
333:
329:
323:
296:
292:
286:
276:
274:
260:, and three
230:
224:
219:
211:
189:
185:
184:
175:
163:
154:
153:
152:
143:
135:
133:
117:
116:
102:
24:
18:
730:Wikispecies
297:Akkermansia
198:, strictly
104:Akkermansia
819:Categories
304:References
262:sulfatases
258:sialidases
142:Ouwerkerk
721:Q27439631
662:220860965
237:, all 21
200:anaerobic
172:Etymology
112:Species:
715:Wikidata
654:21113182
619:25759012
611:21947475
602:11114784
561:20520652
504:27663027
447:28057747
352:27499019
256:, seven
188:, like,
86:Family:
50:Phylum:
43:Bacteria
38:Domain:
802:5615727
789:1679444
763:9406774
745:BacDive
552:3923499
531:Bibcode
495:5103097
474:Bibcode
438:5255907
393:9103655
283:Ecology
246:operons
98:Genus:
74:Order:
62:Class:
750:132956
683:at Bac
660:
652:
617:
609:
599:
559:
549:
502:
492:
445:
435:
391:
350:
252:, one
206:, non-
204:motile
202:, non-
146:. 2016
658:S2CID
615:S2CID
423:(1).
216:mucin
208:spore
160:mucin
144:et al
784:NCBI
771:LPSN
758:GBIF
685:Dive
650:PMID
607:PMID
557:PMID
500:PMID
443:PMID
389:PMID
348:PMID
289:oxic
243:rRNA
239:tRNA
225:The
642:doi
597:PMC
589:doi
547:PMC
539:doi
490:PMC
482:doi
433:PMC
425:doi
379:doi
338:doi
229:of
194:is
821::
799::
786::
773::
760::
747::
732::
717::
656:.
648:.
636:.
613:.
605:.
595:.
585:68
583:.
579:.
555:.
545:.
537:.
525:.
521:.
498:.
488:.
480:.
470:82
468:.
464:.
441:.
431:.
419:.
415:.
401:^
387:.
375:47
373:.
369:.
346:.
334:66
332:.
328:.
312:^
272:.
664:.
644::
638:9
621:.
591::
563:.
541::
533::
527:4
506:.
484::
476::
449:.
427::
421:5
395:.
381::
354:.
340::
322:"
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.