33:
1272:
1302:
340:
1103:
Turck, Dominique; Bohn, Torsten; Castenmiller, Jacqueline; De Henauw, Stefaan; Hirsch-Ernst, Karen Ildico; Maciuk, Alexandre; Mangelsdorf, Inge; McArdle, Harry J; Naska, Androniki; Pelaez, Carmen; Pentieva, Kristina; Siani, Alfonso; Thies, Frank; Tsabouri, Sophia; Vinceti, Marco; Cubadda, Francesco;
938:
Shuoker, Bashar; Pichler, Michael J.; Jin, Chunsheng; Sakanaka, Hiroka; Wu, Haiyang; Gascueña, Ana MartĂnez; Liu, Jining; Nielsen, Tine Sofie; Holgersson, Jan; Nordberg
Karlsson, Eva; Juge, Nathalie; Meier, Sebastian; Morth, Jens Preben; Karlsson, Niclas G.; Abou Hachem, Maher (2023-04-01).
277:
can then get access to the de-capped O-glycans and the mucin peptide chain, both of which it can utilize as an energy source. The released monosaccharides are distributed to the environment where other mucus-associated gut bacteria can utilize them. This way
1104:
Frenzel, Thomas; Heinonen, Marina; Marchelli, Rosangela; Neuhäuser-Berthold, Monika; Poulsen, Morten; Prieto
Maradona, Miguel; Schlatter, Josef Rudolf; van Loveren, Henk; Ackerl, Reinhard; Knutsen, Helle Katrine (September 2021).
988:
van Passel, Mark W. J.; Kant, Ravi; Zoetendal, Erwin G.; Plugge, Caroline M.; Derrien, Muriel; Malfatti, Stephanie A.; Chain, Patrick S. G.; Woyke, Tanja; Palva, Airi; de Vos, Willem M.; Smidt, Hauke (3 March 2011).
247:
is found in about 90% of healthy humans, makes up about 1% to 3% of the fecal microbiota and colonizes the gut during the first year of life. Its prevalence can decrease with age or in disease states.
286:
which aid in growth of other bacteria and maintain healthy mucus turnover. It also maintains microbial balance by competing with and inhibiting the over-growth of other mucin degrading bacteria.
1430:
833:
Ouwerkerk, Janneke P.; van der Ark, Kees C. H.; Davids, Mark; Claassens, Nico J.; Finestra, Teresa Robert; de Vos, Willem M.; Belzer, Clara; Schloss, P. D. (1 December 2016).
1443:
282:
contributes to nutrient-sharing in gut associated microbial communities. Mucin degradation can also lead to the production of beneficial products such as
387:, "are safe and well tolerated in overweight and obese individuals." However, its safety for use as a treatment during disease states is unestablished.
1404:
1417:
1052:
Caputo, Aurélia; Dubourg, Grégory; Croce, Olivier; Gupta, Sushim; Robert, Catherine; Papazian, Laurent; Rolain, Jean-Marc; Raoult, Didier (2015).
290:
is culturable under anaerobic conditions on medium containing porcine gastric mucin or synthetic medium containing protein source with glucose,
941:"Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria"
257:
as its sole source of carbon, nitrogen and energy, and is hence considered a specialist. It starts the mucin degradation process by removing
1489:
778:"Disease-associated dysbiosis and potential therapeutic role of Akkermansia muciniphila, a mucus degrading bacteria of gut microbiome"
32:
1494:
660:
and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology"
1422:
1155:"Effect of inulin, galacto-oligosaccharides, and polyphenols on the gut microbiota, with a focus on Akkermansia muciniphila"
1292:
354:
40:
1356:
1484:
1448:
414:
351:
about antibiotic resistance genes -- Urmite article makes reference to type-strain resistance genes; need a source.
232:
185:
1318:
716:"Rational consideration of Akkermansia muciniphila targeting intestinal health: advantages and challenges"
410:
283:
295:
192:
is Muc (=ATCC BAA-835 =CIP 107961). It is under preliminary research for its potential association with
146:
98:
86:
1391:
1266:
1217:
1106:"Safety of pasteurised Akkermansia muciniphila as a novel food pursuant to Regulation (EU) 2015/2283"
1006:
846:
608:
110:
1204:
Derrien, Muriel; Collado, M. Carmen; Ben-Amor, Kaouther; Salminen, Seppo; de Vos, Willem M. (2008).
597:"Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity"
291:
1277:
1206:"The Mucin Degrader Akkermansia muciniphila Is an Abundant Resident of the Human Intestinal Tract"
893:
Iwaza, Rim; Wasfy, Reham Magdy; Dubourg, Grégory; Raoult, Didier; Lagier, Jean-Christophe (2022).
212:
193:
51:
231:
It colonizes the gastrointestinal tract of humans and other animals and can be found within the
188:
at
Wageningen University of the Netherlands. It belongs to the phylum Verrucomicrobiota and its
1456:
1378:
1243:
1182:
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1153:
Tian, Ruocen; Yu, Leilei; Tian, Fengwei; Zhao, Jianxin; Chen, Wei; Zhai, Qixiao (2024-05-07).
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995:, a Dedicated Intestinal Mucin Degrader, and Its Use in Exploring Intestinal Metagenomes"
654:
Dao, Maria
Carlota; Everard, Amandine; Aron-Wisnewsky, Judith; et al. (March 2016).
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353:
Please expand the section to include this information. Further details may exist on the
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835:"Adaptation of Akkermansia muciniphila to the Oxic-Anoxic Interface of the Mucus Layer"
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472:
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391:
1054:"Whole-genome assembly of Akkermansia muciniphila sequenced directly from human stool"
1478:
940:
208:
1383:
438:
Zhang, Ting; Li, Qianqian; Cheng, Lei; Buch, Heena; Zhang, Faming (November 2019).
401:
Muc as a novel food, provided the cells are killed beyond the limit of detection.
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Proceedings of the
National Academy of Sciences of the United States of America
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Everard, Amandine; Belzer, Clara; Geurts, Lucie; et al. (28 May 2013).
556:: a conserved intestinal symbiont that acts as the gatekeeper of our mucosa"
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Aggarwal, Vidushi; Sunder, Sushant; Verma, Smita
Rastogi (2022-12-01).
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236:
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174:
is a human intestinal symbiont, isolated from human feces. It is a
508:
gen. nov., sp. nov., a human intestinal mucin-degrading bacterium"
328:
254:
220:
175:
512:
International
Journal of Systematic and Evolutionary Microbiology
240:
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1316:
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899:: The state of the art, 18 years after its first discovery"
714:
Luo, Yuheng; Lan, Cong; Li, Hua; et al. (2022-10-17).
1290:
1325:
440:"Akkermansia muciniphila is a promising probiotic"
327:Urmite was sequenced in its entirety from a human
545:
543:
497:
495:
493:
491:
8:
178:-degrading bacterium belonging to the genus
235:of the epithelial crypts as well as in the
184:, discovered in 2004 by Muriel Derrien and
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20:
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265:capping sugars from the end of the mucin
1297:
1286:- the Bacterial Diversity Metadatabase
430:
1210:Applied and Environmental Microbiology
839:Applied and Environmental Microbiology
310:of the type strain contains 2,664,102
7:
888:
886:
771:
769:
767:
709:
707:
705:
14:
239:. It specifically resides at the
223:-forming, oval-shaped bacterium.
1300:
338:
318:contains 5,644 unique proteins.
1:
903:Frontiers in Gastroenterology
1020:10.1371/journal.pone.0016876
720:npj Biofilms and Microbiomes
41:Scanning electron micrograph
269:chain with fucosidases and
1511:
1490:Bacteria described in 2004
957:10.1038/s41467-023-37533-6
916:10.3389/fgstr.2022.1024393
794:10.1007/s12223-022-00973-6
732:10.1038/s41522-022-00338-4
677:10.1136/gutjnl-2014-308778
1262:"Akkermansia muciniphila"
1071:10.1186/s13062-015-0041-1
152:
145:
52:Scientific classification
50:
39:
30:
23:
1122:10.2903/j.efsa.2021.6780
411:galacto-oligosaccharides
233:intestinal mucosal layer
1436:akkermansia-muciniphila
1357:Akkermansia muciniphila
1327:Akkermansia muciniphila
1280:Akkermansia muciniphila
993:Akkermansia muciniphila
897:Akkermansia muciniphila
658:Akkermansia muciniphila
622:10.1073/pnas.1219451110
554:Akkermansia muciniphila
506:Akkermansia muciniphila
456:10.1111/1751-7915.13410
444:Microbial Biotechnology
419:Akkermansia muciniphila
399:Akkermansia muciniphila
381:Akkermansia muciniphila
284:short chain fatty acids
171:Akkermansia muciniphila
156:Akkermansia muciniphila
45:Akkermansia muciniphila
25:Akkermansia muciniphila
1495:Gram-negative bacteria
349:is missing information
227:Ecology and metabolism
945:Nature Communications
550:de Vos, W.M. (2017).
525:10.1099/ijs.0.02873-0
296:N-acetylgalactosamine
1267:Encyclopedia of Life
1230:10.1128/AEM.01226-07
859:10.1128/AEM.01641-16
782:Folia Microbiologica
573:10.1099/mic.0.000444
502:Derrien, M. (2004).
16:Species of bacterium
1222:2008ApEnM..74.1646D
1159:Food & Function
1011:2011PLoSO...616876V
851:2016ApEnM..82.6983O
613:2013PNAS..110.9066E
292:N-acetylglucosamine
243:-anoxic interface.
194:metabolic disorders
162:Derrien et al. 2004
138:A. muciniphila
1171:10.1039/d4fo00428k
552:"Microbe Profile:
421:in the human gut.
415:relative abundance
99:Verrucomicrobiales
1485:Verrucomicrobiota
1472:
1471:
1457:Open Tree of Life
1319:Taxon identifiers
845:(23): 6983–6993.
607:(22): 9066–9071.
383:, either live or
375:Human consumption
372:
371:
167:
166:
75:Verrucomicrobiota
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273:, respectively.
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87:Verrucomicrobiae
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1198:Further reading
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991:"The Genome of
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253:is able to use
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111:Akkermansiaceae
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413:increases the
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392:European Union
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322:A. muciniphila
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288:A. muciniphila
280:A. muciniphila
275:A. muciniphila
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245:A. muciniphila
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363:February 2023
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347:This section
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209:gram-negative
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186:Willem de Vos
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147:Binomial name
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560:Microbiology
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1351:Wikispecies
951:(1): 1833.
396:pasteurized
385:pasteurized
263:sialic acid
211:, strictly
190:type strain
181:Akkermansia
124:Akkermansia
1479:Categories
425:References
312:base pairs
308:chromosome
271:sialidases
200:Morphology
1342:Q15020908
1179:2042-650X
965:2041-1723
925:2813-1169
802:1874-9356
740:2055-5008
726:(1): 81.
464:1751-7915
355:talk page
213:anaerobic
132:Species:
1336:Wikidata
1248:18083887
1187:38590256
1140:34484452
1090:25888298
1064:(1): 5.
1039:21390229
999:PLOS ONE
974:10067855
877:27663027
820:35596115
758:36253412
696:26100928
641:23671105
582:28530168
534:15388697
482:31006995
331:sample.
316:proteome
314:and its
302:Genomics
267:O-glycan
106:Family:
70:Phylum:
63:Bacteria
58:Domain:
1410:3229029
1366:BacDive
1307:Biology
1264:at the
1239:2258631
1218:Bibcode
1131:8409316
1081:4333879
1030:3048395
1007:Bibcode
868:5103097
847:Bibcode
811:9122250
749:9576740
632:3670398
609:Bibcode
473:6801136
118:Genus:
94:Order:
82:Class:
1449:239935
1423:959114
1397:973598
1293:Portal
1282:at Bac
1246:
1236:
1185:
1177:
1138:
1128:
1088:
1078:
1037:
1027:
971:
963:
923:
875:
865:
818:
808:
800:
756:
746:
738:
694:
639:
629:
580:
532:
480:
470:
462:
325:strain
259:fucose
237:caecum
219:, non-
217:motile
215:, non-
1462:39156
1384:65V7S
1371:17849
379:Oral
329:feces
255:mucin
221:spore
207:is a
176:mucin
1444:NCBI
1431:LPSN
1418:ITIS
1405:GBIF
1284:Dive
1244:PMID
1183:PMID
1175:ISSN
1136:PMID
1086:PMID
1035:PMID
961:ISSN
921:ISSN
873:PMID
816:PMID
798:ISSN
754:PMID
736:ISSN
692:PMID
637:PMID
578:PMID
564:1635
530:PMID
478:PMID
460:ISSN
405:Diet
390:The
294:and
261:and
241:oxic
1392:EoL
1379:CoL
1234:PMC
1226:doi
1167:doi
1126:PMC
1118:doi
1076:PMC
1066:doi
1025:PMC
1015:doi
969:PMC
953:doi
911:doi
863:PMC
855:doi
806:PMC
790:doi
744:PMC
728:doi
682:hdl
672:doi
664:Gut
627:PMC
617:doi
605:110
568:doi
520:doi
468:PMC
452:doi
417:of
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