300:, splenomegaly (enlarged spleen), anemia, rear leg weakness, seizures and black tarry stool. Additional symptoms include poor reproduction and/or oral bleeding/gastrointestinal bleeding. Lesions can also be found within the pelt depending on the severity of the disease. This virus can unfortunately reduce fitness of wild mink especially, by disturbing both the productivity within adult females and the overall survivor rates of both juveniles and adults. Likewise, in the mink kits that survive, it infects the alveolar cells and ultimately causes respiratory distress, possibly leading to death.
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183:
247:
Aleutian disease was first recognized in ranch-raised mink in 1956. The disease was so named because it was first found in mink with the
Aleutian coat color gene, a gun-metal grey pelt. It was assumed that the disease was a result of poor genetics, but it was later found that minks of all coat colors
311:
There is currently no known treatment for
Aleutian virus. When evidence of ADV shows in a ferret, it is strongly recommended that a CEP (counterimmunoelectrophoresis) blood test or an IFA (immunofluorescent antibody) test be done. The CEP test is usually faster and less expensive than the IFA test,
283:
A lethal infection in mink, the
Aleutian disease virus lies dormant in ferrets until stress or injury allows it to surface. While the parvovirus itself causes little or no harm to the ferret host, the large number of antibodies produced in response to the presence of the virus results in a systemic
316:
allow for rapid and accurate detection as well as determination of the amount of viron present. Prevention is best accomplished by stopping the spread of ADV. Any new ferret, or those which have been confirmed as serum positive for the virus should be perpetually isolated from other ferrets. All
262:
Aleutian disease has also more currently been found among free range mink throughout Europe and North
America. It is speculated that the disease has been transferred from farmed mink to those in the wild. This is most commonly due to escapees within farms, who when free are hybridizing with wild
259:-infected mink, making suspensions, and injecting all the mink on their ranch. This practice led to a severe outbreak of AD on a Connecticut ranch, with a mortality of almost 100% in less than 6 months. The disease spread from minks to ferrets, as the two were raised on the same farms.
312:
but the IFA test is more sensitive and can detect the disease in borderline cases. A method had been employed successfully to eliminate this virus from an infected herd of mink. Additionally modern methods such as Real-Time
275:. It is transferred through bodily fluids, and also be transmitted in utero or by direct/indirect contact with those mink who are infected. Once symptoms have been indicated, the mink is certain to die.
675:
985:
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This is a growing concern within mink producers as it is the most significant infectious disease affecting farmed mink worldwide.
1018:
963:
45:
385:"Amdoparvoviruses in small mammals: expanding our understanding of parvovirus diversity, distribution, and pathology"
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1013:
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family within mink, ferrets, otters, polecats, stone and pine martens and within other carnivores such as skunks,
853:"Driving forces behind the evolution of the Aleutian mink disease parvovirus in the context of intensive farming"
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items that may have come into contact with the infected ferret should be cleaned with a 10% bleach solution.
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Once symptoms show themselves, the disease progresses rapidly, usually to death within a few months.
198:
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were susceptible to the disease—but tend to have a lower mortality compared with
Aleutian mink.
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In the 1960s, it was common practice for mink ranchers to make their own distemper vaccines by
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235:, foxes and raccoons. This is most commonly explained as because they all share resources and
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17:
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Canuti M, O'Leary KE, Hunter BD, Spearman G, Ojkic D, Whitney HG, Lang AS (January 2016).
27:
Disease of mustelids caused by a highly contagious parvovirus (carnivore amdoparvovirus 1)
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Jepsen JR, d'Amore F, Baandrup U, Clausen MR, Gottschalck E, Aasted B (December 2009).
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mink. There are different strains of this disease which have been documented.
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401:
543:
Persson S, Jensen TH, Blomström AL, Appelberg MT, Magnusson U (2015-03-30).
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886:
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808:
752:"The pathogenesis of Aleutian disease of mink. 3. Immune complex arteritis"
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588:
474:
420:
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439:"Aleutian mink disease virus in furbearing mammals in Nova Scotia, Canada"
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suppression and death. The symptoms are chronic, progressive weight loss,
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297:
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236:
605:
Nituch LA, Bowman J, Beauclerc KB, Schulte-Hostedde AI (2011-07-18).
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919:
607:"Mink farms predict Aleutian disease exposure in wild American mink"
57:
840:
ELIMINATION OF PATHOGENIC INFECTION IN FARMED ANIMAL POPULATIONS
202:
923:
545:"Aleutian mink disease virus in free-ranging mink from Sweden"
492:. Ontario Ministry of Agriculture, Food and Rural Affairs
227:. The virus has been found as a natural infection in the
668:"Viral Diseases of Mink: Mink: Merck Veterinary Manual"
186:
A mink, one of the hosts of
Carnivore amdoparvovirus 1
346:
International
Committee on Taxonomy of Viruses (ICTV)
932:
8:
750:Porter DD, Larsen AE, Porter HG (May 1973).
490:"Aleutian Disease in Mink. Agdex#: 475/662"
920:
29:
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816:
767:
640:
630:
578:
568:
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793:"Aleutian mink disease virus and humans"
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383:Canuti M, Whitney HG, Lang AS (2015).
7:
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25:
756:The American Journal of Pathology
488:Tapscott, Brian (October 2015).
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710:from the original on 2016-12-02
678:from the original on 2016-12-02
1:
513:"Aleutian Disease in Ferrets"
443:Acta Veterinaria Scandinavica
797:Emerging Infectious Diseases
632:10.1371/journal.pone.0021693
570:10.1371/journal.pone.0122194
217:, ADV), a highly contagious
197:, is a disease which causes
907:Aleutian mink disease virus
174:Aleutian mink disease virus
18:Aleutian mink disease virus
1040:
964:Carnivore amdoparvovirus 1
934:Carnivore amdoparvovirus 1
700:"Aleutian Disease in Mink"
437:Farid AH (February 2013).
370:Carnivore amdoparvovirus 1
340:Carnivore amdoparvovirus 1
211:Carnivore amdoparvovirus 1
157:Carnivore amdoparvovirus 1
34:Carnivore amdoparvovirus 1
389:Frontiers in Microbiology
171:
164:
39:
32:
730:"Aleutian Disease Virus"
402:10.3389/fmicb.2015.01119
338:"ICTV Taxonomy history:
288:, resulting in eventual
456:10.1186/1751-0147-55-10
809:10.3201/eid1512.090514
672:www.merckvetmanual.com
215:Aleutian disease virus
187:
1019:Animal viral diseases
913:NCBI Taxonomy Browser
307:Testing and treatment
185:
704:www.omafra.gov.on.ca
199:spontaneous abortion
41:Virus classification
623:2011PLoSO...621693N
561:2015PLoSO..1022194P
209:. It is caused by
195:mink plasmacytosis
188:
1014:Mustelid diseases
1001:
1000:
926:Taxon identifiers
869:10.1093/ve/vew004
519:on 1 October 2002
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16:(Redirected from
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515:. Archived from
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193:, also known as
191:Aleutian disease
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555:(3): e0122194.
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213:(also known as
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108:Quintoviricetes
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803:(12): 2040–2.
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366:Amdoparvovirus
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224:Amdoparvovirus
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1024:Parvovirinae
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733:. Retrieved
728:Williams B.
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521:. Retrieved
517:the original
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494:. Retrieved
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362:Parvovirinae
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358:Parvoviridae
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349:. Retrieved
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267:Transmission
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255:tissue from
253:homogenizing
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132:Parvoviridae
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120:Piccovirales
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107:
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84:Shotokuvirae
83:
72:Monodnaviria
71:
64:
54:(unranked):
33:
958:Wikispecies
351:18 December
294:bone marrow
1008:Categories
714:2016-12-01
682:2016-12-01
511:Deeney A.
496:26 October
324:References
286:vasculitis
273:contagious
229:Mustelidae
219:parvovirus
949:Q18973651
449:(1): 10.
257:distemper
151:Species:
79:Kingdom:
943:Wikidata
915:. 28314.
887:27774297
827:19961696
708:Archived
676:Archived
651:21789177
611:PLOS ONE
589:25822750
549:PLOS ONE
475:23394546
421:26528267
395:: 1119.
298:lethargy
279:Symptoms
237:habitats
166:Synonyms
127:Family:
91:Phylum:
991:1511862
878:4989880
818:3044528
778:4576760
769:1903963
735:7 April
642:3138738
619:Bibcode
580:4379071
557:Bibcode
523:7 April
466:3602201
412:4600916
243:History
207:ferrets
139:Genus:
115:Order:
103:Class:
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233:genets
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368:>
364:>
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203:minks
65:Realm
58:Virus
986:NCBI
883:PMID
823:PMID
774:PMID
737:2008
647:PMID
585:PMID
525:2008
498:2018
471:PMID
417:PMID
353:2018
205:and
973:CoL
873:PMC
865:doi
813:PMC
805:doi
764:PMC
637:PMC
627:doi
575:PMC
565:doi
461:PMC
451:doi
407:PMC
397:doi
314:PCR
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