45:. Animal models of epilepsy and seizures can be divided into three basic categories: genetic animal models, chemically induced models, and electrically induced models. New models are using light-gated ion channels to turn on cell firing and these are part of optogenetic induction models of epilepsy.
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Cela, Elvis; McFarlan, Amanda R.; Chung, Andrew J.; Wang, Taiji; Chierzi, Sabrina; Murai, Keith K.; Sjöström, P. Jesper (March 27, 2019).
134:"Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs"
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Sarkisian, Matthew R. (31 May 2001). "Overview of the
Current Animal Models for Human Seizure and Epileptic Disorders".
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have helped to advance the understanding of how normal brains develop epilepsy (a process known as
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Chang, Bernard S.; Lowenstein, Daniel H. (25 September 2003). "Epilepsy".
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182:"An Optogenetic Kindling Model of Neocortical Epilepsy"
41:which have in common a predisposition to recurrent
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132:Löscher, Wolfgang (31 May 2011).
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198:10.1038/s41598-019-41533-2
29:), and have been used in
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37:. Epilepsy is a set of
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111:10.1056/NEJMra022308
35:antiepileptic drugs
31:pre-clinical trials
186:Scientific Reports
43:epileptic seizures
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27:Epileptogenesis
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49:References
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39:syndromes
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22:epilepsy
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