35:
3635:, hyperleucocytosis, neutropenia, thrombocytopenia, ventricular tachycardia, prolonged QT interval, torsades de pointes, complete atrioventricular block, peripheral neuropathy, hyperglycaemia, hypokalaemia, hypomagnesaemia, elevation of bilirubin or aminotransferases, hepatotoxicity and secondary malignancies.
3164:
Neutropenia, thrombocytopenia, lymphopenia, hypertension, left ventricular dysfunction, heart failure, blood clots, thyroid dysfunction, electrolyte anomalies, pancreatitis (uncommon), hepatic failure (uncommon), prolonged QT interval (rare), torsades de pointes (rare), GI perforation (rare), fistula
1342:
Myelosuppression, peripheral neuropathy, hypersensitivity, fluid retention, heart failure (uncommon), pulmonary toxicity (rare), radiation recall (rare), scleroderma-like skin changes (rare), Stevens–Johnson syndrome (rare), toxic epidermal necrolysis (rare), seizures (rare) and encephalopathy (rare)
3611:
Fluid retention, palpitations, tachycardia, hepatotoxicity (uncommon), heart failure (uncommon), hypertension (uncommon), arrhythmia (uncommon), syncope (uncommon), cardiomyopathy (rare), cardiomegaly (rare), MI (rare), pulmonary hypertension (rare), interstitial lung disease (rare) and pancreatitis
3053:
Hypertension, QT interval prolongation, haemorrhage, blood clots, neutropenia, thrombocytopenia, neutropenia, thrombocytopenia, elevated thyroid-stimulating hormone, hypothyroidism, electrolyte disturbances, hypo- or hyperglycaemia, torsades de pointes (uncommon), heart failure (uncommon), hepatic
2965:
Myelosuppression, fluid retention, GI bleeding, electrolyte anomalies, left ventricular dysfunction (uncommon), heart failure (uncommon), pulmonary oedema (uncommon), kidney failure (uncommon), angiooedema (rare), anaphylaxis (rare), GI perforation (rare), hepatotoxicity (rare), avascular necrosis
2634:
Infusion-related reactions, neutropenia, arrhythmias, infection, thrombocytopenia (uncommon), anaemia (uncommon), angina (uncommon), myocardial infarction (uncommon), heart failure (uncommon), haemolytic anaemia (rare), aplastic anaemia (rare), serum sickness (rare), severe skin conditions (rare),
3430:
Blood clots, neutropenia (dose-limiting), thrombocytopenia (dose-limiting), anaemia, infection, hypotension, hypokalaemia, hypothyroidism, Stevens–Johnson syndrome, toxic epidermal necrolysis, angioedema, pneumonitis, hepatotoxicity and secondary malignancies (mostly myelodysplastic syndrome and
1597:
Myelosuppression, pulmonary fibrosis, pulmonary infiltrates, seizure, brain oedema, cerebrospinal leaks, subdural fluid collection, intracranial infection, hypotension (uncommon), tachycardia (uncommon), decrease in kidney size (reversible), uraemia (uncommon), kidney failure (uncommon), severe
1365:
Hypersensitivity, myelosuppression, peripheral neuropathy, myocardial infarction (uncommon), arrhythmias (uncommon), pulmonary toxicity (rare), radiation recall (rare), scleroderma-like skin changes (rare), Stevens–Johnson syndrome (rare), toxic epidermal necrolysis (rare), seizures (rare) and
3325:
Anaemia, Red blood cell sedimentation rate increased, thrombocytopenia, thrombocytosis, neutropenia, anaphylaxis, hypersensitivity, diabetes mellitus, hyperuricaemia, psychiatric disturbances (rare), convulsions (very rare), conjunctivitis, vasculitis (very rare), GI haemorrhage (very rare),
2815:
Diarrhoea, thrombocytopenia, neutropenia, hepatotoxicity, QT interval prolongation, kidney failure, pleural effusion, pericarditis (uncommon/rare), acute pancreatitis (uncommon/rare), GI haemorrhage (uncommon/rare), anaphylactic shock (uncommon/rare), acute pulmonary oedema (uncommon/rare),
3240:
Infusion reactions, impaired wound healing, hyperglycaemia, hypercholesterolaemia, hypertriglyceridaemia, neutropenia, lymphopenia, thrombocytopenia, anaemia, bleeding, kidney failure, hypokalaemia, hypophosphataemia, pneumonitis, bowel perforation (uncommon) and intracerebral bleeding and
2029:
Myelosuppression, peripheral neuropathy, anaphylaxis, nausea and vomiting (30-90%), hypokalaemia, metabolic acidosis, interstitial lung disease (uncommon), ototoxicity (rare), reversible posterior leucoencephalopathy syndrome (rare), immune-mediated cytopenias (rare) and hepatic sinusoidal
3559:(uncommon), hepatic failure (rare), pancreatitis (rare), leucopenia (rare), neutropenia (rare), pure red cell aplasia (rare), agranulocytosis (rare), extrapyramidal syndrome (rare), reduced BMD with long-term use, pleural effusion (rare) and multiorgan hypersensitivity reaction (rare).
3144:
Hypertension, skin reactions, bleeding, neutropenia, thrombocytopenia, lymphopenia, peripheral neuropathy, thyroid dysfunction, electrolyte anomalies, myocardial ischaemia or infarctions, heart failure (uncommon), GI perforation (uncommon), pancreatitis (uncommon), reversible posterior
3220:
Pleural effusion, hyperglycaemia, hypercholesterolaemia, hypertriglyceridaemia, neutropenia, lymphopenia, thrombocytopenia, anaemia, bleeding, kidney failure, hypokalaemia, hypophosphataemia, pneumonitis, impaired wound healing (uncommon), anaphylaxis (rare) and angiooedema (rare).
3473:
Peripheral neuropathy, depression, thromboembolism, bradycardia, orthostatic hypotension, leucopenia, hypothyroidism, thrombocytopenia (uncommon), Stevens–Johnson syndrome (rare), toxic epidermal necrolysis (rare), pneumonitis (rare), hepatotoxicity (rare) and hearing loss (rare).
2300:
Hypertension, thromboembolisms, heart failure, bleeding, neutropenia, thrombocytopenia, GI perforation, fistula formation, hypertensive encephalopathy, pulmonary hypertension, reversible posterior leucoencephalopathy syndrome, nasal septum perforation and osteonecrosis of the jaw.
3379:
Differentiation syndrome, hyperleucocytosis, elevated cholesterol and triglycerides, arrhythmias, pancreatitis, elevated liver enzymes, thrombosis, intracranial hypertension and pseudotumour cerebri (mainly in children), anxiety, depression and genital ulceration (rare).
3649:
Catalyses the conversion of the amino acid L-asparagine to aspartic acid and thereby reduces the availability of L-asparagine to leukaemic cells. Unlike normal cells, certain types of leukaemic cells do not synthesise L-asparagine, which is essential for cell growth and
2111:
Peripheral neuropathy, neutropenia, thrombocytopenia, anaemia, orthostatic hypotension, hepatitis (uncommon/rare), haemorrhage (uncommon/rare), heart failure (uncommon/rare), seizures (uncommon/rare), progressive multifocal leucoencephalopathy (PML) and hearing loss.
2491:
Fatigue, rash, musculoskeletal pain, itching, diarrhea, nausea, asthenia, cough, shortness of breath, constipation, decreased appetite, back pain, joint pain, upper respiratory tract infection, abnormal temperature increases, headache, abdominal pain, and vomiting.
3470:, mycobacterial infection, recurrent aphthous ulcers, severe recurrent aphthous stomatitis, primary brain malignancies, HIV-associated wasting syndrome, Crohn's disease, Kaposi's sarcoma, myelodysplastic syndrome and haematopoietic stem cell transplantation.
1631:
Myelosuppression, hallucinations (rare), seizures (rare), sterile cystitis (rare), hepatotoxicity (rare), severe pneumonitis (rare), Stevens–Johnson syndrome (rare), toxic epidermal necrolysis (rare) and drug fever (rare). Secondary malignancies.
1566:
Myelosuppression, seizures (high dose), tachycardia (high dose), hepatic sinusoidal obstruction syndrome (high dose), Addison-like syndrome (rare), pulmonary fibrosis (rare), cataracts (rare) and hepatitis (rare). Secondary malignancies.
3628:
Refractory or relapsed acute promyelocytic leukaemia. Orphan indications include: acute myeloid leukaemia, chronic lymphocytic leukaemia, malignant glioma, myelodysplastic syndrome, multiple myeloma, liver cancer and chronic myeloid
822:
Myelosuppression, pulmonary toxicity, hepatotoxicity, neurotoxicity (high dose or intrathecal administration), anaphylactic reactions (rare), Stevens–Johnson syndrome (rare), Toxic
Epidermal Necrolysis (rare), kidney failure (rare),
1983:
Germ cell tumours (including testicular cancer), ovarian cancer, cervical cancer, small cell and non-small cell lung cancer, mesothelioma, squamous cell head and neck cancer, oesophageal cancer, gastric cancer, bladder cancer and
3883:
2912:
Skin reactions, diarrhoea, GI bleeds, anaemia, dehydration, interstitial lung disease (uncommon), hepatic failure (rare), hepatorenal syndrome (rare), GI perforation (rare) and ulcerative keratitis (rare).
3450:
Neutropenia, anaemia, pneumonia, thrombocytopenia, hypercalcaemia, hyperglycaemia, kidney failure, lymphopenia, hyponatraemia, hypocalcaemia, hypokalaemia, peripheral neuropathy and thromboembolism.
6442:
3169:(rare), thrombotic thrombocytopenic purpura (rare), nephrotic syndrome (rare), hypersensitivity (rare), angiooedema (rare), toxic epidermal necrolysis (rare) and Stevens–Johnson syndrome (rare).
3073:
Hypertension, neutropenia, leucopenia, anaemia, thrombocytopenia, lymphopenia, pleural effusion, heart failure, peripheral neuropathy, haemorrhage, blood clots, pancreatitis and infection.
1967:
Myelosuppression, nausea and vomiting (30-90%), peripheral neuropathy, ototoxicity, anaphylaxis, acute kidney failure (rare), haemolytic uraemic syndrome (rare) and loss of vision (rare).
3556:
2787:
Hypertension, thyroid dysfunction, blood clots, electrolyte disturbances, GI perforation (rare), fistula formation (rare), reversible posterior leucoencephalopathy syndrome (rare) and
1697:, heart failure (rare), pulmonary fibrosis (rare), hepatic sinusoidal obstruction syndrome (rare), water retention resembling SIADH (rare) and seizures (rare). Secondary malignancies.
2938:
Skin reactions, diarrhoea, dehydration, haemorrhage, interstitial lung disease (uncommon), pancreatitis (uncommon), hepatitis (uncommon), allergy (uncommon), hepatic failure (rare),
1842:
Myelosuppression, pulmonary fibrosis and pneumonitis (uncommon), skin necrosis (uncommon), anaphylaxis, hepatic sinusoidal obstruction syndrome and SIADH. Secondary malignancies.
3295:
Leucopenia, anaemia, lactic dehydrogenase increased, hypochromic anaemia, hyperlipidaemia, hypercholesteraemia, hypothyroidism, haemorrhage, hypertension and kidney dysfunction.
3018:, prolonged QT interval (uncommon), peripheral arterial occlusive disease (uncommon), pancreatitis (uncommon), pleural effusion (uncommon) and pericardial effusion (uncommon).
1429:
Refractory metastatic melanoma, childhood acute lymphoblastic leukaemia, chronic myeloid leukaemia in blast crises, neuroblastoma, non-small cell lung cancer and breast cancer.
3086:
Multikinase inhibitor for RET, VEGFR1, VEGFR2, VEGFR3, KIT, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR2, TIE2, DDR2, Trk2A, Eph2A, RAF-1, BRAF, BRAFV600E, SAPK2, PTK5, and Bcr-Abl.
2839:
Lymphopenia, neutropenia, hypophosphataemia, hypokalaemia, peripheral neuropathy, blood clots, QT interval prolongation, bradycardia, pneumonia, pneumonitis, kidney cyst,
2173:
Myelosuppression, peripheral neuropathy, myocardial ischaemia (uncommon/rare), supraventricular arrhythmia (uncommon/rare) and hypersensitivity reaction (uncommon/rare).
4710:
6435:
3675:
Live, attenuated
Mycobacterium bovis, which produces a local inflammatory reaction, resulting in elimination or reduction of superficial tumour lesions of the bladder.
4091:
Robak, Tadeusz; Korycka, Anna; Robak, Ewa (2005-12-31). "Older and New
Formulations of Cladribine. Pharmacology and Clinical Efficacy in Hematological Malignancies".
2231:
Myelosuppression, neurotoxicity, pulmonary fibrosis (uncommon/rare), pneumonitis (uncommon/rare), haemolysis (uncommon/rare) and hepatic dysfunction (uncommon/rare).
1323:
Myelosuppression, diarrhoea, kidney failure, hypersensitivity, severe GI reactions (including perforation, ileus, colitis, etc.; all rare) and peripheral neuropathy
872:(uncommon), hepatitis (rare), colitis (rare), pneumonitis (rare), radiation recall (rare), Stevens–Johnson syndrome (rare) and toxic epidermal necrolysis (rare).
3092:
Anaemia, lymphopenia, thrombocytopenia, electrolyte anomalies, hepatotoxicity, hypertension, hypothyroidism, neutropenia, myocardial ischaemia or infarction.
5410:
2962:
Philadelphia chromosome-positive acute lymphoblastic leukaemia, chronic myeloid leukaemia, GI stromal tumour and myelodysplastic/myeloproliferative diseases.
951:
893:
852:
3067:
Multikinase inhibitor (BEGFR, PDGFR, FGFR, EPH receptors and SRC families of kinases, and KIT, RET, TIE2 and FLT3), that also inhibits T135I Bcr-Abl kinase.
6428:
2635:
pulmonary infiltrates (rare), pneumonitis (rare), cranial neuropathy (vision or hearing loss; rare) and progressive multifocal leucoencephalopathy (rare).
2323:
Infusion-related reactions, skin reactions, hypomagnesaemia, hypocalcaemia, hypokalaemia, blood clots, interstitial lung disease and aseptic meningitis.
2275:
357:
3694:
Interleukin 2 combined with diphtheria toxin which binds to the interleukin receptor on immune cells and introduces the diphtheria toxin into the cell.
1991:(rare), optic neuritis (rare), reversible posterior leucoencephalopathy syndrome (rare), seizures (rare), ECG changes (rare) and heart failure (rare).
1264:
Myelosuppression, hypersensitivity reactions, Stevens–Johnson syndrome (rare), peripheral neuropathy (uncommon) and secondary malignancies (especially
717:
Myelosuppression, neurotoxicity, immune hypersensitivity, hyponatraemia, thrombotic thrombocytopenic purpura and microangiopathic hemolytic anaemia.
3736:
IM – Intramuscular. IV – Intravenous. IA – Intra-arterial. SC – Subcutaneous. PO – Per os, oral. IP – Intrapleural. IB – Intrabladder. Preg. cat. -
1545:
1410:
Lymphomas, acute lymphoblastic leukaemia, multiple myeloma, sarcoma, brain tumours, Wilms' tumour, neuroblastoma and primary immune thrombocytopenia
7434:
7077:
558:
Myelosuppression, diarrhoea, cardiotoxicity, GI ulceration and bleeding (uncommon), cerebellar syndrome (uncommon), encephalopathy (uncommon) and
2167:
Promotes tubulin polymerisation and stabilises microtubular function, causing cell cycle arrest at G2/M phase and subsequently induces apoptosis
2274:, pneumonitis, arrhythmias and hypersensitivity reactions (rare), autoimmune haemolytic anaemia (rare), autoimmune thrombocytopenia (rare) and
1676:
1626:
6386:
4703:
3981:
3923:
3893:
3866:
3832:
3326:
hepatitis (very rare), erythema multiforme, Stevens–Johnson syndrome, toxic epidermal necrolysis, arthritis (very rare), rhabdomyolysis and
1987:
Nephrotoxicity, nausea and vomiting (30-100%), myelosuppression, electrolyte anomalies, peripheral neuropathy, ototoxicity and anaphylaxis,
6570:
2766:
Myelosuppression, hypertension, dehydration, blood clots, GI perforation and reversible posterior leucoencephalopathy syndrome (uncommon).
3054:
failure (uncommon), GI perforation (uncommon), fistula formation (uncommon) and reversible posterior leucoencephalopathy syndrome (rare).
3545:(orphan) and the following off-label uses: cervical cancer, melanoma, mesothelioma, acute myeloid leukaemia and myelodysplastic syndrome.
5993:
2840:
621:
2882:
Fluid retention, myelosuppression, haemorrhage, hypertension, electrolyte anomalies, cardiac dysfunction (rare), heart failure (rare),
2131:
Myelosuppression, anaphylaxis, radiation recall, hepatotoxicity and hepatic sinusoidal obstruction syndrome (common in Wilms' tumour).
7548:
5145:
5101:
4979:
2477:
2071:
Inhibits DNA and to a lesser extent RNA synthesis, produces single and double strand breaks in DNA possibly by free radical formation.
662:
Myelosuppression, hepatotoxicity, GI ulceration (rare), pancreatitis (rare) and secondary leukaemia (rare) or myelodysplasia (rare).
4904:
3997:
Spurgeon, Stephen; Yu, Margaret; Phillips, John D.; Epner, Elliot M. (2009-08-01). "Cladribine: not just another purine analogue?".
3704:(uncommon/rare), Hyper/hypothyroidism (uncommon/rare), pancreatitis (uncommon/rare) and toxic epidermal necrolysis (uncommon/rare).
3188:
Diarrhoea, hypertension, QT interval prolongation, depression, electrolyte anomalies, hypothyroidism and GI perforation (uncommon).
1836:
90:
3625:
Not fully understood. Induces partial differentiation and promotes apoptosis of leukaemic cells and may also inhibit angiogenesis.
1339:
Breast cancer, non-small cell lung cancer, ovarian cancer, prostate cancer, squamous cell head and neck cancer and gastric cancer.
7873:
6968:
6494:
4696:
2932:
2926:
2903:
2723:
2625:
2314:
1688:
1359:
Ovarian cancer, breast cancer, non-small cell lung cancer, AIDS-related Kaposi's sarcoma, cervical cancer, germ cell cancer and
5626:
5420:
6039:
5041:
4931:
3542:
2453:
471:
4126:
Hentosh, Patricia; Peffley, Dennis M. (2010-01-01). "The cladribine conundrum: deciphering the drug's mechanism of action".
1762:
Myelosuppression, haemorrhagic cystitis, nephrotoxicity, neurotoxicity and cardiac toxicity (rare). Secondary malignancies.
2154:, venous thromboembolism, congestive heart failure, pulmonary embolism, myocardial infarction and cerebrovascular failure.
1014:
Myelosuppression, skin cancer (rare), oedema (rare), hallucinations (rare), seizures (rare) and pulmonary toxicity (rare).
8260:
8188:
5961:
5944:
5819:
5583:
4961:
3370:
3196:
2876:
2621:
2512:
1622:
1514:
755:
682:
678:
648:
644:
463:
345:
293:
253:
2943:
2371:
Hepatic veno-occlusive disease, myelosuppression, cytokine release syndrome, hypersensitivity and electrolyte anomalies.
494:
311:
263:
7314:
5693:
5289:
1680:
1046:
Diarrhoea, myelosuppression, pulmonary infiltrates (uncommon), bradycardia (uncommon), ileus (rare) and colitis (rare).
869:
764:
Myelosuppression, hepatotoxicity, peripheral neuropathy (uncommon), intestinal necrosis (rare) and perforation (rare).
6471:
6403:
5895:
4688:
3166:
617:
7495:
3740:. The preferred pregnancy category is Australian, but if it is unavailable the pregnancy category given is American.
714:, peripheral T-cell lymphoma (orphan), cutaneous T cell lymphoma (orphan) and chronic lymphocytic leukaemia (orphan).
4640:
3726:
Skin reactions, secondary malignancies (mostly squamous cell carcinoma), anaphylaxis (rare) and hypotension (rare).
1648:
Cutaneous T-Cell
Lymphoma, metastatic carcinoma, leukaemias, lymphomas, polycythemia vera and bronchogenic carcinoma
8219:
7620:
7469:
7218:
6720:
5075:
3606:
3145:
leucoencephalopathy syndrome (rare), hepatitis (rare), nephrotic syndrome (rare) and prolonged QT interval (rare).
2939:
2007:
Non-small cell lung cancer, oesophageal cancer, uterine cervical cancer, head and neck cancer and urothelial cancer
1391:
Hodgkin lymphoma, germ cell tumours, non-small cell lung cancer, bladder cancer and primary immune thrombocytopenia
689:
656:
606:
590:
498:
315:
267:
8013:
6945:
6811:
6524:
6261:
6141:
6131:
4666:
3918:. Koda Kimble and Youngs Applied Therapeutics (10th ed.). Baltimore, MD: Lippincott Williams & Wilkins.
3467:
2872:
2810:
2440:
2343:
1549:
989:
902:
Febrile neutropenia (uncommon) renal failure (uncommon), peripheral neuropathy (uncommon), hepatotoxicity (rare)
812:
349:
307:
149:
141:
8048:
8006:
6955:
6481:
6313:
6246:
6216:
5834:
5084:
3665:
3632:
3350:
3138:
2698:
HER2-positive breast cancer, gastric cancer, pancreatic cancer (orphan) and gastro-oesophageal junction cancer.
2671:
2629:
1561:
1106:
993:
983:
453:
283:
2349:
Hypercholesterolaemia, cataract, urinary retention, hypocalcaemia, osteonecrosis of the jaw and anaphylaxis.
8141:
8105:
8043:
6451:
6391:
6298:
6116:
5831:
5317:
5165:
5092:
3349:
Hypercholesterolaemia, hypertriglyceridaemia, gastrointestinal disturbances, liver damage, leucocytosis and
3070:
T135I positive
Chronic myeloid leukaemia and Philadelphia chromosome positive acute lymphoblastic leukaemia.
2804:
2757:
2667:
2151:
2086:
2075:
1892:
1721:
1587:
1265:
1201:
1102:
1005:
943:
915:
885:
844:
786:
759:
459:
341:
297:
145:
4226:
Timmer, Antje; Patton, Petrease H.; Chande, Nilesh; McDonald, John W. D.; MacDonald, John K. (2016-05-18).
2052:
Unclear, reactive intermediates covalently bind to microsomal proteins and DNA, possibly causing DNA damage
8146:
8100:
7323:
6806:
6535:
6196:
6186:
5919:
5761:
3407:
3263:
2817:
1888:
1583:
858:
652:
162:
4565:
1936:
Bone marrow suppression, rhabdomyolysis, embryo-fetal toxicity, capillary leak syndrome, hepatotoxicity
736:
Breast, colorectal cancer, gallbladder, gastrointestinal tract, head and neck, liver and pancreas cancer.
8265:
8198:
8179:
6881:
6821:
6791:
6694:
6530:
6420:
5468:
5285:
5255:
5115:
3914:
Alldredge BK, Corelli RL, Ernst ME, Guglielmo BJ, Jacobson PA, Kradjan WA, Williams BR (February 2012).
2883:
2354:
1694:
865:
625:
586:
490:
384:
243:
205:
135:
4283:
1872:, myelosuppression, nausea and vomiting (>90%), jaundice and nephrogenic diabetes insipidus (rare).
960:
Neutropenia, febrile neutropenia (uncommon), renal failure (uncommon) peripheral neuropathy (uncommon)
2833:
ALK, Hepatocyte Growth Factor
Receptor (HGFR, c-Met), and Recepteur d'Origine Nantais (RON) inhibitor.
2701:
Cardiac dysfunction, infusion-related reactions, peripheral neuropathy and pulmonary toxicity (rare).
1816:
Hodgkin disease, chronic leukimia, lung cancer, polycythemia vera, T-cell lymphoma, mycosia fungoides
262:(uncommon), neurotoxicity (rare), renal impairment (rare), pulmonary interstitial infiltrates (rare),
208:, GI haemorrhage (uncommon), cerebellar syndrome (uncommon), encephalopathy (uncommon) and diarrhoea.
8151:
7996:
7986:
7866:
6736:
6631:
6468:
5866:
5743:
5264:
5180:
2782:
2617:
2560:
2469:
2465:
2457:
2436:
2376:
1518:
1197:
947:
919:
889:
848:
804:
800:
711:
536:
514:
467:
410:
Myelosuppression, hyperglycaemia, hypoalbuminaemia, hypomagnesaemia, hypokalaemia, hyperkalaemia and
249:
2320:
Squamous cell head and neck cancer or EGFR-positive and KRAS wild-type metastatic colorectal cancer.
2297:
Colorectal, breast, ovarian, renal cell and non-squamous non-small cell lung cancer and glioblastoma
8038:
7970:
7589:
6856:
6846:
6666:
6151:
6051:
6030:
5751:
5573:
5405:
5136:
5032:
3701:
3686:
3515:
Histone deacetylase inhibitor, hence inducing alterations in gene expression in the affected cells.
3267:
2995:
Diarrhoea, interstitial lung disease (uncommon), hepatotoxicity (uncommon) and anaphylaxis (rare).
2663:
1130:
1009:
705:
404:
383:
cerebral and cerebellar dysfunction, ocular toxicity, pulmonary toxicity, severe GI ulceration and
1091:
Inhibits DNA and RNA synthesis by intercalating DNA base pairs. Inhibits DNA repair by inhibiting
8131:
7244:
6876:
6861:
6781:
5209:
4641:"Amnesteem, Claravis (isotretinoin) dosing, indications, interactions, adverse effects, and more"
4159:
4030:
3552:
3538:
3327:
1988:
1862:
1684:
1652:
1557:
1413:
Neurotoxicity, anaphylaxis (rare), myocardial ischaemia (rare) and myocardial infarction (rare).
1360:
1209:
997:
828:
816:
624:(rare), anaphylactoid reaction (rare), reversible posterior leucoencephalopathy syndrome (rare),
540:
486:
259:
199:
6358:
1671:
Breast cancer, lymphoma, acute lymphoblastic leukaemia, chronic lymphocytic leukaemia, sarcoma,
548:
5239:
5219:
5204:
4539:
3656:
Allergic reactions, haemorrhagic and thrombotic events, uraemia, pancreatitis, hyperglycaemia,
1394:
Neurotoxicity, myelosuppression, myocardial ischaemia (rare) and myocardial infarction (rare).
1261:
Testicular cancer, ovarian cancer, lung cancer, acute myeloid leukaemia, lymphomas and sarcomas
688:
Myelosuppression, pleural effusion, seizures, tumour lysis syndrome and a condition similar to
8234:
8224:
8136:
7950:
6921:
6333:
5907:
4741:
4622:
4516:
4485:
4454:
4423:
4348:
4317:
4265:
4247:
4208:
4151:
4143:
4108:
4073:
4065:
4022:
4014:
3977:
3919:
3889:
3862:
3828:
3521:
Electrolyte anomalies, anaemia, thrombocytopenia, neutropenia, lymphopenia and ECG anomalies.
1858:
1591:
925:
598:
552:
544:
528:
191:
3165:
formation (rare), seizures (rare), reversible posterior leucoencephalopathy syndrome (rare),
8123:
8001:
6761:
6603:
6598:
6338:
6095:
5810:
5444:
5429:
5150:
4612:
4604:
4255:
4239:
4198:
4190:
4135:
4100:
4057:
4006:
3969:
3968:. Recent Results in Cancer Research. Vol. 184. Heidelberg: Springer. pp. 159–170.
3617:
3425:
3419:
2564:
2461:
2432:
1898:
Myelosuppression, Stevens–Johnson syndrome (rare), pneumonitis (rare) and hepatitis (rare).
1672:
1660:
1281:
1255:
1138:
1126:
1092:
974:
411:
154:
1101:
Myelosuppression, cardiotoxicity, anaphylaxis (rare), secondary malignancies (particularly
8239:
8214:
7859:
7851:
5777:
5739:
5530:
4952:
4867:
3940:
3657:
3548:
2675:
1805:
1717:
1318:
1205:
1060:
1037:
4515:, Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012,
4484:, Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012,
4453:, Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012,
4422:, Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012,
4347:, Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012,
4316:, Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases, 2012,
48:
Please help update this article to reflect recent events or newly available information.
8161:
8119:
7698:
7596:
7544:
7142:
6455:
6397:
5931:
5522:
5016:
4880:
4767:
4737:
4724:
4617:
4592:
4260:
4227:
4203:
4178:
3855:
3015:
2967:
2887:
2568:
2485:
1961:
1847:
1835:
Malignant melanoma of the extremities, multiple myeloma, conditioning treatment before
792:
633:
613:
594:
578:
532:
478:
449:
376:
335:
287:
195:
158:
72:
4228:"Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis"
8254:
7965:
7755:
7645:
7607:
7584:
7516:
7511:
7501:
7277:
7273:
7261:
7068:
6851:
6816:
6636:
6616:
6271:
6231:
5601:
5474:
5355:
5298:
5056:
5005:
4566:"Targretin (bexarotene) dosing, indications, interactions, adverse effects, and more"
4061:
3415:
3411:
3182:
Tyrosine kinase inhibitor (TKI) with selective activity against RET, VEGFR-2 and EGFR
3115:
2788:
2541:
1869:
1786:
1553:
1288:
1134:
1001:
796:
582:
524:
187:
4163:
4034:
7906:
7795:
7780:
7750:
7730:
7612:
7560:
7521:
7409:
7388:
7295:
7257:
7158:
7133:
7129:
7013:
6978:
6931:
6916:
6871:
6746:
6716:
6641:
6459:
6318:
6282:
6166:
6156:
6110:
6106:
6068:
5976:
5766:
5705:
5701:
5682:
5677:
5656:
5645:
5459:
5453:
5439:
5434:
5365:
5360:
5313:
5199:
5066:
5046:
4975:
4924:
4914:
4728:
4720:
4284:"Arranon (nelarabine) dosing, indications, interactions, adverse effects, and more"
4243:
3640:
3488:
3436:
3398:
3335:
3300:
3255:
3226:
2481:
2473:
2271:
2214:
2136:
2117:
1877:
1637:
1607:
1525:
1503:
1186:
1125:
Breast cancer, lymphomas, sarcomas, bladder cancer, acute lymphoblastic leukaemia,
1083:
935:
877:
824:
808:
778:
506:
427:
372:
364:
319:
303:
221:
182:
174:
166:
66:
4608:
3466:
Multiple myeloma, erythema nodosum leprosum and the following orphan indications:
3321:
Skin reactions, blood lipid anomalies, increased platelet count and osteoporosis.
4194:
2992:-positive breast cancer, stomach cancer (orphan) and oesophageal cancer (orphan).
8229:
8169:
8028:
7991:
7914:
7825:
7805:
7800:
7790:
7770:
7745:
7740:
7723:
7671:
7661:
7656:
7651:
7553:
7480:
7450:
7445:
7440:
7424:
7414:
7394:
7269:
7265:
7253:
7249:
7178:
7082:
7028:
7023:
6988:
6926:
6911:
6901:
6896:
6891:
6886:
6866:
6831:
6786:
6766:
6756:
6711:
6676:
6656:
6612:
6575:
6563:
6558:
6520:
6504:
6363:
6343:
6328:
6323:
6308:
6266:
6236:
6176:
6146:
6090:
6063:
5936:
5877:
5849:
5839:
5792:
5756:
5672:
5634:
5616:
5611:
5591:
5568:
5539:
5517:
5497:
5487:
5338:
5323:
5303:
5189:
5120:
5106:
5061:
4994:
4989:
4966:
4941:
4909:
4852:
4815:
4792:
4777:
4772:
4757:
3717:
3709:
3455:
3097:
3078:
2745:
2683:
2640:
2574:
Fatigue, rash, itchiness (pruritus), diarrhea, nausea, joint pain (arthralgia).
2556:
2522:
2449:
2397:
Thrombocytopenia, neutropenia, anaemia, hypotension and secondary malignancies.
2283:
2254:
2159:
2082:
2044:
2015:
1950:
1922:
1729:
1702:
1484:
1456:
1399:
1380:
1307:
1114:
907:
730:
697:
567:
559:
520:
482:
441:
419:
368:
275:
127:
4508:
4477:
4446:
4415:
4389:
4340:
4309:
4104:
1781:
Myelosuppression, pulmonary infiltration and fibrosis. Secondary malignancies.
17:
8174:
8023:
7960:
7924:
7840:
7835:
7810:
7775:
7760:
7735:
7718:
7708:
7666:
7637:
7602:
7568:
7485:
7475:
7455:
7419:
7404:
7399:
7369:
7303:
7299:
7281:
7229:
7208:
7168:
7163:
7102:
7033:
7008:
6983:
6906:
6841:
6801:
6796:
6776:
6771:
6751:
6741:
6731:
6646:
6626:
6608:
6516:
6353:
6256:
6251:
6226:
6221:
6211:
6206:
6201:
6171:
6161:
6126:
6121:
6101:
6056:
6044:
6019:
6014:
6004:
5986:
5981:
5971:
5966:
5924:
5912:
5900:
5872:
5859:
5854:
5824:
5787:
5782:
5720:
5715:
5661:
5606:
5558:
5544:
5492:
5479:
5448:
5381:
5370:
5343:
5333:
5328:
5274:
5229:
5224:
5125:
5089:
5021:
5011:
5000:
4984:
4936:
4919:
4895:
4847:
4835:
4787:
4139:
4010:
3973:
3592:
3564:
3507:
3281:
3206:
3174:
2825:
2653:
2579:
2497:
2402:
2388:
2102:
2094:
2078:, pancreatic cancer, non-Hodgkin's, pleural sclerosing and Hodgkin's lymphoma.
1996:
1748:
1599:
1572:
1437:
1348:
1315:
Microtubule disassembly inhibitor. Arrests cells in late G2 phase and M phase.
1273:
1219:
1167:
1148:
1028:
836:
744:
667:
392:
327:
235:
4251:
4147:
4069:
4018:
2192:
Myelosuppression, pulmonary toxicity and haemolytic uraemic syndrome (rare).
2058:
Myelosuppression, peripheral neuropathy, seizures and hepatotoxicity (rare).
1498:
Myelosuppression, peripheral neuropathy, seizures and hepatotoxicity (rare).
138:
inhibitor and incorporates itself into RNA, hence inhibiting gene expression.
8193:
8079:
8064:
7945:
7929:
7830:
7820:
7815:
7785:
7765:
7713:
7703:
7691:
7686:
7632:
7627:
7573:
7506:
7379:
7374:
7359:
7354:
7349:
7339:
7334:
7329:
7234:
7224:
7203:
7198:
7193:
7188:
7183:
7173:
7153:
7117:
7112:
7107:
7097:
7092:
7059:
7054:
7049:
7018:
6998:
6993:
6836:
6826:
6651:
6499:
6368:
6348:
6303:
6293:
6287:
6191:
6136:
6085:
6009:
5999:
5954:
5941:
5882:
5844:
5772:
5710:
5651:
5640:
5596:
5553:
5512:
5506:
5502:
5464:
5391:
5386:
5376:
5348:
5308:
5269:
5244:
5234:
5194:
4840:
4830:
4825:
4820:
4782:
3578:
Thrombocytopenia, anaemia, QT interval prolongation and pulmonary embolism.
3526:
3358:
3161:
renal cell carcinoma, GI stromal tumour and pancreatic neuroendocrine tumour
3150:
3126:
3059:
3023:
3000:
2975:
2918:
2895:
2848:
2796:
2601:
2424:
2328:
2306:
2178:
2063:
1972:
1824:
1767:
1651:
Thrombosis, myelosuppression (common), hyperuricaemia, erythema multiforme,
1418:
1328:
1247:
1051:
602:
353:
4626:
4593:"Targeted isotretinoin in neuroblastoma: kinetics, genetics, or absorption"
4520:
4489:
4458:
4427:
4352:
4321:
4269:
4212:
4155:
4112:
4026:
3406:
Numerous actions; anti-angiogenesis (via inhibition of VEGF release), anti-
3158:
Multikinase inhibitor (including VEGF & PDGF receptor tyrosine kinases)
2536:
Skin reactions, electrolyte anomalies, anaphylaxis and angiooedema (rare).
4077:
8183:
8074:
8033:
8018:
7891:
7883:
7580:
7344:
7148:
7087:
7043:
7003:
6973:
6726:
6590:
6586:
6511:
6277:
6241:
6181:
5949:
5887:
5667:
5563:
5535:
5214:
5051:
4540:"Vandetanib dosing, indications, interactions, adverse effects, and more"
3827:(2013 ed.). Adelaide: The Australian Medicines Handbook Unit Trust.
2951:
2771:
2715:
2552:
2445:
1903:
1618:
1533:
213:
4513:
LiverTox: Clinical and
Research Information on Drug-Induced Liver Injury
4482:
LiverTox: Clinical and
Research Information on Drug-Induced Liver Injury
4451:
LiverTox: Clinical and
Research Information on Drug-Induced Liver Injury
4420:
LiverTox: Clinical and
Research Information on Drug-Induced Liver Injury
4345:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury
4314:
LiverTox: Clinical and Research Information on Drug-Induced Liver Injury
2108:
Multiple myeloma, mantle cell lymphoma and follicular lymphoma (orphan).
8084:
8069:
6684:
5170:
5071:
4885:
4746:
4667:"Isotretinoin 20mg capsules – Summary of Product Characteristics (SPC)"
2740:
Diarrhoea, hypokalaemia, interstitial lung disease and hepatotoxicity.
1713:
Hodgkin lymphoma, metastatic malignant melanoma and soft tissue sarcoma
722:
7955:
7887:
4810:
3217:
Renal cell cancer, pancreatic neuroendocrine tumour and breast cancer
2225:
2128:
Gestational trophoblastic disease, Wilms' tumour and rhabdomyosarcoma
76:
2413:
antibody that causes immune system-mediated lysis of the tagged cell
1069:
Diarrhoea, myelosuppression, interstitial lung disease and allergy.
2010:
Nephrotoxicity, myelosuppression and nausea and vomiting (30-90%).
1724:(rare) and hepatocellular necrosis (rare). Secondary malignancies.
575:
DNA synthesis inhibitor, induces apoptosis specifically in S-phase.
338:
inhibitor, S-phase specific. Incorporates its metabolites into DNA.
7564:
7290:
7124:
7073:
6553:
4048:
Bryson, Harriet M.; Sorkin, Eugene M. (1993-11-01). "Cladribine".
3700:
Infusion reactions, hypocalcaemia, hypotension, thrombocytopenia,
3697:
Cutaneous T cell lymphoma and peripheral T cell lymphoma (orphan).
3044:
3040:
3032:
2865:
2861:
2857:
2410:
2336:
3346:
Refractory acute promyelocytic leukaemia and Alzheimer's disease.
3134:
Multikinase inhibitor (including VEGF and PDGF receptor kinases).
739:
Myelosuppression, diarrhoea, neurotoxicity and hepatitis (rare).
7919:
7679:
7465:
6963:
6689:
6671:
6661:
6621:
6489:
3885:
Goodman & Gilman's The Pharmacological Basis of Therapeutics
3758:
Its use in cancer treatment is purely investigational at present
3600:
3312:
3109:
3105:
3036:
2989:
2983:
2753:
2731:
2727:
2692:
2649:
2610:
2587:
2506:
2384:
2362:
2291:
2262:
407:(orphan), acute myeloid leukaemia and chronic myeloid leukaemia.
7855:
6424:
4692:
3422:
effects. Also stimulates T cells and apoptosis in cancer cells.
2342:
Osteoporosis, including drug- and cancer-related osteoporosis,
2125:
Complexes with DNA interfering with DNA-dependent RNA synthesis
1917:
Myelosupression, embryo-fetal toxicity, hepatotoxicity (rare)
28:
2023:
Reacts with DNA, inducing apoptosis, non-cell cycle specific.
2004:
Reacts with DNA, inducing apoptosis, non-cell cycle specific.
1980:
Reacts with DNA, inducing apoptosis, non-cell cycle specific.
1958:
Reacts with DNA, inducing apoptosis, non-cell cycle specific.
2890:(rare), hypersensitivity (rare) and hepatic failure (rare).
2488:, and esophageal or gastroesophageal junction (GEJ) cancer.
1655:, nausea and vomiting (severe) and secondary malignancies.
1602:(rare) and neuroretinitis (rare). Secondary malignancies.
1066:
Small cell lung cancer, ovarian cancer and cervical cancer
4177:
Ghanem H, Kantarjian H, Ohanian M, Jabbour E (Apr 2013).
3964:
Martens, UM, ed. (2010). "11 5-Azacytidine/Azacitidine".
3653:
Acute lymphoblastic leukaemia and lymphoblastic lymphoma.
2820:(uncommon/rare) and erythema multiforme (uncommon/rare).
2533:
RAS (KRAS or NRAS) wild-type metastatic colorectal cancer
1388:
Microtubule assembly inhibitor. Arrests cells in M phase.
3723:
BRAF kinase mutation V600E-positive Metastatic melanoma.
2026:
Colorectal cancer, oesophageal cancer and gastric cancer
2517:
Neutropenia, pneumonia, infusion reactions, cytopenias
803:, gestational trophoblastic disease, acute leukaemias,
246:
inhibitor, metabolites incorporate themselves into DNA.
2419:
Life-threatening immune mediated reactions and fever.
1432:
Myelosuppression, neurotoxicity and paralytic ileus.
1964:, lung cancer and squamous cell head and neck cancer
8207:
8160:
8118:
8093:
8057:
7979:
7938:
7905:
7898:
7536:
7313:
6954:
6944:
6704:
6585:
6545:
6480:
6467:
6078:
6029:
5809:
5802:
5738:
5692:
5625:
5582:
5419:
5404:
5284:
5254:
5179:
5164:
5135:
5031:
4951:
4894:
4877:
4866:
4802:
4755:
4736:
4390:"Secondary Malignancies: Therapy-Related t-MDS/AML"
4179:"The role of clofarabine in acute myeloid leukemia"
3767:
There is no INN for arsenic trioxide, just the USAN
2886:, arrhythmia (rare), prolonged QT interval (rare),
2365:
antibody that induces apoptosis of the tagged cell.
4128:Expert Opinion on Drug Metabolism & Toxicology
3882:Brunton LL, Chabner B, Knollmann BC, eds. (2011).
3854:
3660:, acute kidney failure and diabetic ketoacidosis.
3861:(65 ed.). London, UK: Pharmaceutical Press.
3447:Multiple myeloma and systemic sclerosis (orphan).
2909:Non-small cell lung cancer and pancreatic cancer.
2189:Anal, bladder, and upper tract urothelial cancers
1693:Myelosuppression, nausea and vomiting (>30%),
3681:Cystitis, BCG infection and contracted bladder.
1159:Breast cancer, gastric cancer and bladder cancer
982:Inhibits DNA synthesis by inhibiting the enzyme
3916:Applied therapeutics: the clinical use of drugs
2394:Non-Hodgkin's lymphoma and follicular lymphoma.
2265:antibody induces apoptosis in the tagged cells.
1810:IV, intra pleural, intra pericardial, topical
433:Metastatic GI adenocarcinoma and stomach cancer
230:Myelosuppression, neurotoxicity and diarrhoea.
2935:-mutation positive non-small cell lung cancer.
2596:Anaphylaxis, cardiac dysfunction and anaemia.
2416:Unresectable or metastatic malignant melanoma.
7867:
6436:
4704:
3776:There is no INN for asparaginase, only a USAN
3050:Renal cell carcinoma and soft tissue sarcoma.
2387:antibody bound with the radioactive isotope,
2170:Locally advanced or metastatic breast cancer.
1467:Breast cancer and non-small cell lung cancer.
1287:Lymphomas, acute lymphoblastic leukaemia and
8:
4093:Recent Patents on Anti-Cancer Drug Discovery
3014:Myelosuppression, electrolyte disturbances,
952:glycinamide ribonucleotide formyltransferase
894:glycinamide ribonucleotide formyltransferase
861:and non-squamous non-small cell lung cancer.
853:glycinamide ribonucleotide formyltransferase
4232:The Cochrane Database of Systematic Reviews
3237:Renal cell cancer and mantle cell lymphoma.
7902:
7874:
7860:
7852:
6951:
6477:
6443:
6429:
6421:
5806:
5416:
5176:
4891:
4874:
4752:
4711:
4697:
4689:
2276:progressive multifocal leucoencephalopathy
1759:Sarcomas, testicular cancer and lymphomas.
827:(rare), skin and bone necrosis (rare) and
358:progressive multifocal leucoencephalopathy
4673:. Alliance Pharmaceuticals. 12 April 2013
4616:
4259:
4202:
3518:Peripheral and cutaneous T cell lymphoma.
3089:Colorectal cancer and GI stromal tumours.
2391:, induces radiation-dependent cell lysis.
489:(uncommon), severe neurotoxicity (rare),
3888:(12th ed.). New York: McGraw-Hill.
3582:
3478:
3388:
3245:
3192:
2705:
2244:
2235:
2222:Inhibits DNA, RNA and protein synthesis.
2209:Hepatotoxicity, Bone marrow suppression
2034:
1940:
1546:haematopoietic stem cell transplantation
1474:
1370:
1297:
1237:
1073:
1018:
964:
801:squamous cell carcinoma of head and neck
768:
117:
108:
81:
3999:Expert Opinion on Investigational Drugs
3942:Martindale: The Complete Drug Reference
3802:
3751:
3537:Migraine prophylaxis, mania, epilepsy,
2144:Antimicrotubule and oestrogenic actions
1933:Advanced liposarcoma and leimyosarcoma
4383:
4381:
4379:
4377:
4375:
4373:
4371:
4369:
4367:
2150:Cardiovascular complications, such as
2081:Pulmonary toxicity, hypersensitivity,
612:Myelosuppression, pulmonary toxicity,
3848:
3846:
3844:
3818:
3816:
3814:
3812:
3810:
3808:
3806:
2816:respiratory failure (uncommon/rare),
1495:Recurrent or advanced ovarian cancer
227:Colorectal, breast and ovarian cancer
7:
3909:
3907:
3905:
1914:Breast, ovarian, and baldder cancer
864:Myelosuppression, renal impairment,
4980:ribonucleotide reductase inhibitors
3391:2.4 Immunomodulatory Agents (IMiDs)
1797:Metastatic small cell lung cancer.
622:thrombotic thrombocytopenic purpura
5146:Ribonucleotide reductase inhibitor
5102:Ribonucleotide reductase inhibitor
3945:. London, UK: Pharmaceutical Press
3853:Joint Formulary Committee (2013).
3481:2.5 Histone deacetylase inhibitors
2478:esophageal squamous cell carcinoma
2346:and hypercalcaemia of malignancies
204:Myelosuppression, cardiotoxicity,
25:
4905:Dihydrofolate reductase inhibitor
3241:Stevens–Johnson syndrome (rare).
3031:Multikinase inhibitor, including
2206:Testicular and germ cell cancers
1837:haemopoietic stem cell transplant
628:(rare) and heart failure (rare).
4062:10.2165/00003495-199346050-00007
3857:British National Formulary (BNF)
2626:granulomatosis with polyangiitis
1689:granulomatosis with polyangiitis
1677:Waldenström's macroglobulinaemia
1627:Waldenström's macroglobulinaemia
400:DNA methyltransferase inhibitor.
33:
4671:electronic Medicines Compendium
3118:and pancreatic cancer (orphan).
1895:, metastatic malignant melanoma
5042:Thymidylate synthase inhibitor
4932:Thymidylate synthase inhibitor
4244:10.1002/14651858.CD000478.pub4
3543:familial adenomatous polyposis
3121:Anaemia and thrombocytopenia.
2652:antibody which is tagged with
2549:Anti-PD-1 monoclonal antibody.
2454:malignant pleural mesothelioma
1740:Metastatic malignant melanoma.
1544:Conditioning treatment before
1021:1.04 Topoisomerase I inhibitor
472:Waldenstrom macroglobulinaemia
1:
8189:Clonally transmissible cancer
4962:Adenosine deaminase inhibitor
4803:Block microtubule disassembly
4609:10.1158/1078-0432.CCR-12-3313
3825:Australian Medicines Handbook
3371:acute promyelocytic leukaemia
2877:acute lymphoblastic leukaemia
2708:2.2 Tyrosine kinase inhibitor
2622:chronic lymphocytic leukaemia
2513:Chronic lymphocytic leukaemia
2435:antibody that functions as a
2268:Chronic lymphocytic leukaemia
2030:obstruction syndrome (rare).
1623:chronic lymphocytic leukaemia
1515:Chronic lymphocytic leukaemia
756:Acute lymphoblastic leukaemia
683:chronic lymphocytic leukaemia
679:Acute lymphoblastic leukaemia
649:acute promyelocytic leukaemia
645:Acute lymphoblastic leukaemia
464:chronic lymphocytic leukaemia
363:Myelosuppression, GI bleeds,
346:acute lymphoblastic leukaemia
294:Acute lymphoblastic leukaemia
254:chronic lymphocytic leukaemia
4195:10.3109/10428194.2012.726722
2966:(rare), myopathy (rare) and
2593:HER2-positive breast cancer.
1681:systemic lupus erythematosus
899:Peripheral T cell lymphomas
870:supraventricular tachycardia
111:1. Cytotoxic antineoplastics
3966:Small molecules in oncology
3167:haemolytic uraemic syndrome
2737:Non-small cell lung cancer.
2238:2. Targeted antineoplastics
1778:Glioma and medulloblastoma.
1521:and non-Hodgkin's lymphoma.
752:Purine synthesis inhibitor.
675:Purine synthesis inhibitor.
641:Purine synthesis inhibitor.
618:haemolytic uraemic syndrome
8282:
8220:Index of oncology articles
6946:Tyrosine kinase inhibitors
4105:10.2174/157489206775246467
3607:Essential thrombocythaemia
3431:acute myeloid leukaemia).
3011:Chronic myeloid leukaemia.
2940:toxic epidermal necrolysis
2836:Non-small cell lung cancer
1687:, systemic vasculitis and
967:1.03 Other antimetabolites
657:inflammatory bowel disease
607:inflammatory bowel disease
499:toxic epidermal necrolysis
403:Myelodysplastic syndrome,
316:toxic epidermal necrolysis
268:toxic epidermal necrolysis
64:
6812:Mirvetuximab soravtansine
6381:
6262:Omacetaxine mepesuccinate
6142:Ciltacabtagene autoleucel
6132:Brexucabtagene autoleucel
4140:10.1517/17425250903393745
4011:10.1517/13543780903071038
3974:10.1007/978-3-642-01222-8
3745:
3730:
3468:graft versus host disease
3292:Cutaneous T cell lymphoma
3185:Medullary thyroid cancer.
3137:Renal cell carcinoma and
3008:Bcr-Abl kinase inhibitor.
2959:Bcr-Abl kinase inhibitor.
2873:chronic myeloid leukaemia
2811:Chronic myeloid leukaemia
2807:and SRc kinase inhibitor.
2344:giant cell tumour of bone
2247:2.1 Monoclonal antibodies
2037:1.11 Miscellaneous others
1598:hepatic toxicity (rare),
1550:chronic myeloid leukaemia
990:Chronic myeloid leukaemia
813:graft-versus-host disease
350:chronic myeloid leukaemia
308:cytokine release syndrome
150:chronic myeloid leukaemia
142:Myelodysplastic syndromes
120:1.01 Nucleoside analogues
84:
42:This article needs to be
6956:Receptor tyrosine kinase
6482:Receptor tyrosine kinase
6314:Talimogene laherparepvec
6247:Nadofaragene firadenovec
6217:Lisocabtagene maraleucel
5166:Topoisomerase inhibitors
5085:DNA polymerase inhibitor
4597:Clinical Cancer Research
3633:Differentiation syndrome
3351:differentiation syndrome
3139:hepatocellular carcinoma
2944:Stevens–Johnson syndrome
2672:myelodysplastic syndrome
2630:microscopic polyangiitis
2624:, rheumatoid arthritis,
2055:Recurrent ovarian cancer
1562:essential thrombocytosis
1109:) and radiation recall.
1107:myelodysplastic syndrome
994:essential thrombocytosis
984:ribonucleotide reductase
495:Stevens–Johnson syndrome
481:, GI bleeds (uncommon),
454:ribonucleotide reductase
312:Stevens–Johnson syndrome
284:Ribonucleotide reductase
264:Stevens–Johnson syndrome
8142:Prostate cancer staging
8106:Paraneoplastic syndrome
6546:Others for solid tumors
6452:Targeted cancer therapy
6117:Axicabtagene ciloleucel
4721:chemotherapeutic agents
4591:Matthay KK (Jan 2013).
4183:Leukemia & Lymphoma
3785:There is no INN for BCG
3732:Abbreviations/Acronyms:
2668:acute myeloid leukaemia
2368:Acute myeloid leukaemia
2228:and Hodgkin's lymphoma.
2152:ischaemic heart disease
2076:squamous cell carcinoma
1943:1.10 Platinum compounds
1893:glioblastoma multiforme
1722:hepatic vein thrombosis
1588:glioblastoma multiforme
1366:encephalopathy (rare).
1266:acute myeloid leukaemia
1202:acute myeloid leukaemia
1103:acute myeloid leukaemia
1006:acute myeloid leukaemia
957:Pneumocystis jirovecii
944:Dihydrofolate reductase
916:Dihydrofolate reductase
886:Dihydrofolate reductase
845:Dihydrofolate reductase
787:Dihydrofolate reductase
760:acute myeloid leukaemia
690:Guillain-Barré syndrome
460:Acute myeloid leukaemia
360:and meningeal leukaemia
342:Acute myeloid leukaemia
298:acute myeloid leukaemia
146:acute myeloid leukaemia
8180:Tumor suppressor genes
8147:Gleason grading system
8101:Precancerous condition
6807:Loncastuximab tesirine
6536:Trastuzumab deruxtecan
6299:Sitimagene ceradenovec
6197:Idecabtagene vicleucel
5762:Methyl aminolevulinate
3823:Rossi, S, ed. (2013).
3366:RXR & RAR agonist.
3308:RXR & RAR agonist.
3264:Retinoic acid receptor
2871:Philadelphia positive
2818:pulmonary hypertension
2779:Multikinase inhibitor.
2662:Grade 3-4 cytopenias,
2659:Non-Hodgkin's lymphoma
1889:Anaplastic astrocytoma
1819:Hepatotoxicity (rare)
1584:Anaplastic astrocytoma
1477:1.09 Alkylating agents
859:Malignant mesothelioma
653:lymphoblastic lymphoma
163:renal tubular acidosis
85:Antineoplastic agents
8199:Carcinogenic bacteria
7939:Malignant progression
6882:Sacituzumab govitecan
6822:Moxetumomab pasudotox
6792:Inotuzumab ozogamicin
6695:Gemtuzumab ozogamicin
6531:Trastuzumab emtansine
6472:monoclonal antibodies
6456:antineoplastic agents
5773:Porphyrin derivatives
5469:Melphalan flufenamide
5116:Hypomethylating agent
4725:antineoplastic agents
2884:myocardial infarction
2856:BCR-ABL, SRC family,
2616:CD20-positive B cell
2355:Gemtuzumab ozogamicin
2203:Blocks RNA synthesis
1695:haemorrhagic cystitis
1240:1.06 Podophyllotoxins
866:peripheral neuropathy
626:myocardial infarction
491:haemorrhagic cystitis
385:peripheral neuropathy
244:DNA methyltransferase
206:hypertriglyceridaemia
136:DNA methyltransferase
75:agents used to treat
8261:Antineoplastic drugs
8152:Dukes classification
6737:Belantamab mafodotin
6102:Asparagine depleters
6031:Receptor antagonists
5945:+abiraterone acetate
3551:, thrombocytopenia,
2868:-β kinase inhibitor.
2783:Renal cell carcinoma
2618:non-Hodgkin lymphoma
2561:head and neck cancer
2470:urothelial carcinoma
2466:head and neck cancer
2458:renal cell carcinoma
2437:checkpoint inhibitor
2377:Ibritumomab tiuxetan
2087:Raynaud's phenomenon
2068:IM, SC, IA, IV or IP
1519:mantle cell lymphoma
1451:As per vinblastine.
1373:1.08 Vinca alkaloids
1198:Non-Hodgkin lymphoma
948:thymidylate synthase
920:thymidylate synthase
890:thymidylate synthase
849:thymidylate synthase
805:non-Hodgkin lymphoma
712:Hairy cell leukaemia
515:Thymidylate synthase
468:non-Hodgkin lymphoma
375:(uncommon/rare) and
250:Hairy cell leukaemia
7971:Sentinel lymph node
7590:Denileukin diftitox
7252:(ALK, ROS1, NTRK),
6857:Polatuzumab vedotin
6847:Oportuzumab monatox
6152:Denileukin diftitox
6052:Retinoid X receptor
5752:Aminolevulinic acid
5574:Triethylenemelamine
5406:Crosslinking of DNA
5137:Deoxyribonucleotide
5076:+gimeracil/oteracil
3939:Sweetman, S (ed.).
3702:Acute kidney injury
3687:Denileukin diftitox
3601:Phosphodiesterase 3
3268:retinoid X receptor
2843:and liver failure.
2664:methaemoglobinaemia
2074:Germ cell tumours,
1076:1.05 Anthracyclines
1010:sickle cell anaemia
733:synthase inhibitor.
706:Adenosine deaminase
591:non-small cell lung
405:sickle cell anaemia
183:Fluorouracilprodrug
98:Mechanism of action
8019:Respiratory system
7276:(ROS1, TRK, ALK),
6782:Enfortumab vedotin
6408:Never to phase III
5210:Etirinotecan pegol
4645:Medscape Reference
4570:Medscape Reference
4544:Medscape Reference
4394:Medscape Reference
4388:Bhatia, S (2008).
4288:Medscape Reference
3738:Pregnancy category
3575:As per romidepsin.
3553:polycystic ovaries
3539:fragile X syndrome
3328:glomerulonephritis
3311:Neuroblastoma and
2763:Colorectal cancer.
2674:, anaphylaxis and
1989:haemolytic anaemia
1863:carcinoid syndrome
1743:Myelosuppression.
1716:Myelosuppression,
1685:glomerulonephritis
1653:haemolytic anaemia
1558:polycythaemia vera
1524:Myelosuppression,
1361:endometrial cancer
1210:multiple sclerosis
998:polycythaemia vera
829:macrocytic anaemia
817:systemic sclerosis
783:SC, IM, IV, IT, PO
487:haemolytic anaemia
477:Myelosuppression,
436:Myelosuppression.
302:Myelosuppression,
260:haemolytic anaemia
258:Myelosuppression,
200:oesophageal cancer
71:This is a list of
8248:
8247:
8235:Cancer and nausea
8114:
8113:
7951:Carcinoma in situ
7849:
7848:
7532:
7531:
6940:
6939:
6922:Tisotumab vedotin
6418:
6417:
6377:
6376:
6334:Tigilanol tiglate
5811:Enzyme inhibitors
5734:
5733:
5730:
5729:
5430:Nitrogen mustards
5400:
5399:
5160:
5159:
4862:
4861:
4447:"Mechlorethamine"
3983:978-3-642-01222-8
3925:978-1-60913-713-7
3895:978-0-07-162442-8
3868:978-0-85711-084-8
3834:978-0-9805790-9-3
3794:
3793:
3720:kinase inhibitor.
3273:Kaposi's sarcoma.
1859:Pancreatic cancer
1592:mycosis fungoides
1548:(high dose, IV),
1528:and tachycardia.
1178:Acute leukaemias.
1043:Colorectal cancer
930:Myelosuppression
926:Colorectal cancer
811:, brain tumours,
599:pancreatic cancer
553:actinic keratoses
545:pancreatic cancer
379:(uncommon/rare).
371:(uncommon/rare),
367:(uncommon/rare),
161:(uncommon/rare),
104:Major toxicities
63:
62:
16:(Redirected from
8273:
8049:Endocrine system
8014:Digestive system
7903:
7876:
7869:
7862:
7853:
7563:peptide against
7136:(AXL, ALK, LTK))
6952:
6762:Dinutuximab beta
6478:
6445:
6438:
6431:
6422:
6339:Tisagenlecleucel
6096:Arsenic trioxide
5807:
5740:Photosensitizers
5531:Alkyl sulfonates
5445:Cyclophosphamide
5417:
5356:Anthracenediones
5177:
5151:Hydroxycarbamide
4892:
4875:
4753:
4713:
4706:
4699:
4690:
4683:
4682:
4680:
4678:
4663:
4657:
4656:
4654:
4652:
4637:
4631:
4630:
4620:
4588:
4582:
4581:
4579:
4577:
4562:
4556:
4555:
4553:
4551:
4536:
4530:
4529:
4528:
4527:
4505:
4499:
4498:
4497:
4496:
4474:
4468:
4467:
4466:
4465:
4443:
4437:
4436:
4435:
4434:
4412:
4406:
4405:
4403:
4401:
4385:
4362:
4361:
4360:
4359:
4337:
4331:
4330:
4329:
4328:
4306:
4300:
4299:
4297:
4295:
4280:
4274:
4273:
4263:
4223:
4217:
4216:
4206:
4174:
4168:
4167:
4123:
4117:
4116:
4088:
4082:
4081:
4045:
4039:
4038:
4005:(8): 1169–1181.
3994:
3988:
3987:
3961:
3955:
3954:
3952:
3950:
3936:
3930:
3929:
3911:
3900:
3899:
3879:
3873:
3872:
3860:
3850:
3839:
3838:
3820:
3786:
3783:
3777:
3774:
3768:
3765:
3759:
3756:
3618:Arsenic trioxide
3585:2.6 Other Agents
3426:Multiple myeloma
2565:Hodgkin lymphoma
2462:Hodgkin lymphoma
2239:
2147:Prostate cancer.
1868:Nephrotoxicity,
1673:multiple myeloma
1661:Cyclophosphamide
1282:Topoisomerase II
1256:Topoisomerase II
1139:multiple myeloma
1131:Kaposi's sarcoma
1098:Acute leukaemias
1093:topoisomerase II
975:Hydroxycarbamide
771:1.02 Antifolates
412:thrombocythaemia
155:Myelosuppression
112:
82:
58:
55:
49:
37:
36:
29:
21:
8281:
8280:
8276:
8275:
8274:
8272:
8271:
8270:
8251:
8250:
8249:
8244:
8203:
8156:
8110:
8089:
8053:
7975:
7934:
7894:
7880:
7850:
7845:
7699:Pi3K inhibitors
7597:mTOR inhibitors
7528:
7309:
7280:(VEGFR, FGFR),
6936:
6700:
6581:
6541:
6463:
6449:
6419:
6414:
6413:
6398:Clinical trials
6373:
6079:Other/ungrouped
6074:
6025:
5798:
5778:Porfimer sodium
5726:
5688:
5621:
5578:
5408:
5396:
5280:
5250:
5168:
5156:
5131:
5027:
4947:
4883:
4881:antimetabolites
4879:
4878:DNA precursors/
4870:
4868:DNA replication
4858:
4798:
4768:Vinca alkaloids
4744:
4732:
4717:
4687:
4686:
4676:
4674:
4665:
4664:
4660:
4650:
4648:
4639:
4638:
4634:
4590:
4589:
4585:
4575:
4573:
4564:
4563:
4559:
4549:
4547:
4538:
4537:
4533:
4525:
4523:
4507:
4506:
4502:
4494:
4492:
4476:
4475:
4471:
4463:
4461:
4445:
4444:
4440:
4432:
4430:
4416:"Lurbinectedin"
4414:
4413:
4409:
4399:
4397:
4387:
4386:
4365:
4357:
4355:
4339:
4338:
4334:
4326:
4324:
4308:
4307:
4303:
4293:
4291:
4282:
4281:
4277:
4238:(5): CD000478.
4225:
4224:
4220:
4176:
4175:
4171:
4125:
4124:
4120:
4090:
4089:
4085:
4047:
4046:
4042:
3996:
3995:
3991:
3984:
3963:
3962:
3958:
3948:
3946:
3938:
3937:
3933:
3926:
3913:
3912:
3903:
3896:
3881:
3880:
3876:
3869:
3852:
3851:
3842:
3835:
3822:
3821:
3804:
3799:
3790:
3789:
3784:
3780:
3775:
3771:
3766:
3762:
3757:
3753:
3734:
3669:
3658:hyperammonaemia
3643:
3586:
3549:Hyperammonaemia
3482:
3392:
3276:Oedema, rashes
3249:
3234:mTOR inhibitor.
3214:mTOR inhibitor.
3200:
2709:
2676:hyperthyroidism
2530:EGFR inhibitor.
2441:inhibiting PD-1
2439:, specifically
2248:
2237:
2186:Cross-links DNA
2038:
1944:
1930:Alkylates DNA.
1911:Alkylates DNA.
1813:Alkylates DNA.
1806:Mechlorethamine
1800:Hepatotoxicity
1794:Alkylates DNA.
1718:agranulocytosis
1492:Alkylates DNA.
1478:
1374:
1319:Prostate cancer
1301:
1241:
1230:Bladder cancer.
1206:prostate cancer
1129:, AIDS-related
1077:
1061:topoisomerase I
1038:topoisomerase I
1022:
968:
772:
549:Bowen's disease
318:(uncommon) and
121:
110:
69:
59:
53:
50:
47:
38:
34:
23:
22:
18:Antineoplastics
15:
12:
11:
5:
8279:
8277:
8269:
8268:
8263:
8253:
8252:
8246:
8245:
8243:
8242:
8237:
8232:
8227:
8222:
8217:
8211:
8209:
8205:
8204:
8202:
8201:
8196:
8191:
8186:
8177:
8172:
8166:
8164:
8162:Carcinogenesis
8158:
8157:
8155:
8154:
8149:
8144:
8139:
8134:
8128:
8126:
8116:
8115:
8112:
8111:
8109:
8108:
8103:
8097:
8095:
8091:
8090:
8088:
8087:
8082:
8077:
8072:
8067:
8061:
8059:
8055:
8054:
8052:
8051:
8046:
8044:Nervous system
8041:
8036:
8031:
8026:
8021:
8016:
8011:
8010:
8009:
8007:nasopharyngeal
8004:
7999:
7994:
7983:
7981:
7977:
7976:
7974:
7973:
7968:
7963:
7958:
7953:
7948:
7942:
7940:
7936:
7935:
7933:
7932:
7927:
7922:
7917:
7911:
7909:
7900:
7896:
7895:
7881:
7879:
7878:
7871:
7864:
7856:
7847:
7846:
7844:
7843:
7838:
7833:
7828:
7823:
7818:
7813:
7808:
7803:
7798:
7793:
7788:
7783:
7778:
7773:
7768:
7763:
7758:
7753:
7748:
7743:
7738:
7733:
7728:
7727:
7726:
7721:
7716:
7711:
7706:
7696:
7695:
7694:
7689:
7676:
7675:
7674:
7669:
7664:
7659:
7654:
7646:CDK inhibitors
7642:
7641:
7640:
7635:
7630:
7617:
7616:
7615:
7610:
7605:
7593:
7577:
7557:
7545:fusion protein
7540:
7538:
7534:
7533:
7530:
7529:
7527:
7526:
7525:
7524:
7519:
7514:
7509:
7504:
7491:
7490:
7489:
7488:
7483:
7478:
7461:
7460:
7459:
7458:
7453:
7448:
7443:
7430:
7429:
7428:
7427:
7422:
7417:
7412:
7407:
7402:
7397:
7384:
7383:
7377:
7365:
7364:
7363:
7362:
7357:
7352:
7347:
7342:
7337:
7332:
7319:
7317:
7311:
7310:
7308:
7307:
7286:
7285:
7284:(VEGFR, EGFR).
7240:
7239:
7238:
7237:
7232:
7227:
7214:
7213:
7212:
7211:
7206:
7201:
7196:
7191:
7186:
7181:
7176:
7171:
7166:
7161:
7156:
7151:
7138:
7137:
7121:
7115:
7110:
7105:
7100:
7095:
7090:
7085:
7065:
7064:
7063:
7062:
7057:
7052:
7042:HER1/EGFR and
7038:
7037:
7031:
7026:
7021:
7016:
7011:
7006:
7001:
6996:
6991:
6986:
6981:
6976:
6960:
6958:
6949:
6942:
6941:
6938:
6937:
6935:
6934:
6929:
6924:
6919:
6914:
6909:
6904:
6899:
6894:
6889:
6884:
6879:
6874:
6869:
6864:
6859:
6854:
6849:
6844:
6839:
6834:
6829:
6824:
6819:
6814:
6809:
6804:
6799:
6794:
6789:
6784:
6779:
6774:
6769:
6764:
6759:
6754:
6749:
6744:
6739:
6734:
6729:
6724:
6721:+hyaluronidase
6714:
6708:
6706:
6702:
6701:
6699:
6698:
6681:
6680:
6654:
6649:
6644:
6639:
6634:
6629:
6595:
6593:
6583:
6582:
6580:
6579:
6567:
6561:
6549:
6547:
6543:
6542:
6540:
6539:
6533:
6528:
6525:+hyaluronidase
6508:
6502:
6486:
6484:
6475:
6465:
6464:
6450:
6448:
6447:
6440:
6433:
6425:
6416:
6415:
6412:
6411:
6410:
6409:
6406:
6395:
6389:
6383:
6382:
6379:
6378:
6375:
6374:
6372:
6371:
6366:
6361:
6356:
6351:
6346:
6341:
6336:
6331:
6326:
6321:
6316:
6311:
6306:
6301:
6296:
6291:
6285:
6274:
6269:
6264:
6259:
6254:
6249:
6244:
6239:
6234:
6229:
6224:
6219:
6214:
6209:
6204:
6199:
6194:
6189:
6184:
6179:
6174:
6169:
6164:
6159:
6154:
6149:
6144:
6139:
6134:
6129:
6124:
6119:
6114:
6098:
6093:
6088:
6082:
6080:
6076:
6075:
6073:
6072:
6060:
6048:
6035:
6033:
6027:
6026:
6024:
6023:
6017:
6012:
6007:
6002:
5990:
5984:
5979:
5974:
5969:
5958:
5952:
5947:
5939:
5932:PARP inhibitor
5928:
5916:
5904:
5892:
5891:
5890:
5885:
5880:
5875:
5863:
5857:
5852:
5847:
5842:
5828:
5815:
5813:
5804:
5800:
5799:
5797:
5796:
5790:
5785:
5780:
5769:
5764:
5759:
5754:
5748:
5746:
5736:
5735:
5732:
5731:
5728:
5727:
5725:
5724:
5718:
5713:
5708:
5698:
5696:
5690:
5689:
5687:
5686:
5680:
5675:
5664:
5659:
5654:
5649:
5637:
5631:
5629:
5623:
5622:
5620:
5619:
5614:
5609:
5604:
5599:
5594:
5588:
5586:
5584:Platinum-based
5580:
5579:
5577:
5576:
5571:
5566:
5561:
5549:
5548:
5542:
5526:
5525:
5520:
5515:
5510:
5500:
5495:
5483:
5482:
5477:
5472:
5462:
5457:
5451:
5442:
5437:
5425:
5423:
5414:
5402:
5401:
5398:
5397:
5395:
5394:
5389:
5384:
5379:
5374:
5368:
5363:
5352:
5346:
5341:
5336:
5331:
5326:
5321:
5311:
5306:
5299:Anthracyclines
5294:
5292:
5282:
5281:
5279:
5278:
5272:
5260:
5258:
5252:
5251:
5249:
5248:
5242:
5237:
5232:
5227:
5222:
5217:
5212:
5207:
5202:
5197:
5185:
5183:
5174:
5162:
5161:
5158:
5157:
5155:
5154:
5141:
5139:
5133:
5132:
5130:
5129:
5123:
5111:
5110:
5097:
5096:
5080:
5079:
5069:
5064:
5059:
5054:
5049:
5037:
5035:
5029:
5028:
5026:
5025:
5019:
5017:Mercaptopurine
5008:
5003:
4998:
4992:
4987:
4971:
4970:
4957:
4955:
4949:
4948:
4946:
4945:
4939:
4928:
4922:
4917:
4912:
4900:
4898:
4889:
4872:
4864:
4863:
4860:
4859:
4857:
4856:
4844:
4838:
4833:
4828:
4823:
4818:
4806:
4804:
4800:
4799:
4797:
4796:
4790:
4785:
4780:
4775:
4763:
4761:
4750:
4734:
4733:
4719:Intracellular
4718:
4716:
4715:
4708:
4701:
4693:
4685:
4684:
4658:
4632:
4603:(2): 311–313.
4583:
4557:
4531:
4500:
4469:
4438:
4407:
4363:
4341:"Trimetrexate"
4332:
4310:"Pralatrexate"
4301:
4275:
4218:
4189:(4): 688–698.
4169:
4118:
4083:
4056:(5): 872–894.
4040:
3989:
3982:
3956:
3931:
3924:
3901:
3894:
3874:
3867:
3840:
3833:
3801:
3800:
3798:
3795:
3792:
3791:
3788:
3787:
3778:
3769:
3760:
3750:
3749:
3743:
3742:
3728:
3727:
3724:
3721:
3715:
3712:
3706:
3705:
3698:
3695:
3692:
3689:
3683:
3682:
3679:
3678:Bladder cancer
3676:
3673:
3670:
3662:
3661:
3654:
3651:
3647:
3644:
3637:
3636:
3630:
3626:
3623:
3620:
3614:
3613:
3609:
3604:
3598:
3595:
3589:
3588:
3584:
3580:
3579:
3576:
3573:
3570:
3567:
3561:
3560:
3546:
3535:
3532:
3529:
3523:
3522:
3519:
3516:
3513:
3510:
3504:
3503:
3500:
3497:
3494:
3491:
3485:
3484:
3480:
3476:
3475:
3471:
3464:
3461:
3458:
3452:
3451:
3448:
3445:
3442:
3439:
3433:
3432:
3428:
3423:
3404:
3401:
3395:
3394:
3390:
3386:
3385:
3374:
3367:
3364:
3361:
3355:
3354:
3347:
3344:
3341:
3338:
3332:
3331:
3316:
3309:
3306:
3303:
3297:
3296:
3293:
3290:
3287:
3284:
3278:
3277:
3274:
3271:
3270:(RXR) agonist.
3261:
3258:
3252:
3251:
3247:
3243:
3242:
3238:
3235:
3232:
3229:
3223:
3222:
3218:
3215:
3212:
3209:
3203:
3202:
3194:
3190:
3189:
3186:
3183:
3180:
3177:
3171:
3170:
3162:
3159:
3156:
3153:
3147:
3146:
3142:
3135:
3132:
3129:
3123:
3122:
3119:
3113:
3103:
3100:
3094:
3093:
3090:
3087:
3084:
3081:
3075:
3074:
3071:
3068:
3065:
3062:
3056:
3055:
3051:
3048:
3029:
3026:
3020:
3019:
3016:hyperglycaemia
3012:
3009:
3006:
3003:
2997:
2996:
2993:
2987:
2981:
2978:
2972:
2971:
2968:rhabdomyolysis
2963:
2960:
2957:
2954:
2948:
2947:
2936:
2930:
2924:
2921:
2915:
2914:
2910:
2907:
2901:
2898:
2892:
2891:
2888:kidney failure
2880:
2869:
2854:
2851:
2845:
2844:
2837:
2834:
2831:
2828:
2822:
2821:
2813:
2808:
2802:
2799:
2793:
2792:
2785:
2780:
2777:
2774:
2768:
2767:
2764:
2761:
2751:
2748:
2742:
2741:
2738:
2735:
2721:
2718:
2712:
2711:
2707:
2703:
2702:
2699:
2696:
2689:
2686:
2680:
2679:
2660:
2657:
2646:
2643:
2637:
2636:
2632:
2614:
2607:
2604:
2598:
2597:
2594:
2591:
2585:
2582:
2576:
2575:
2572:
2569:stomach cancer
2550:
2547:
2544:
2538:
2537:
2534:
2531:
2528:
2525:
2519:
2518:
2515:
2510:
2503:
2500:
2494:
2493:
2489:
2486:gastric cancer
2443:
2430:
2427:
2421:
2420:
2417:
2414:
2408:
2405:
2399:
2398:
2395:
2392:
2382:
2379:
2373:
2372:
2369:
2366:
2360:
2357:
2351:
2350:
2347:
2340:
2334:
2331:
2325:
2324:
2321:
2318:
2312:
2309:
2303:
2302:
2298:
2295:
2289:
2286:
2280:
2279:
2269:
2266:
2260:
2257:
2251:
2250:
2246:
2242:
2241:
2233:
2232:
2229:
2223:
2220:
2217:
2211:
2210:
2207:
2204:
2201:
2198:
2194:
2193:
2190:
2187:
2184:
2181:
2175:
2174:
2171:
2168:
2165:
2162:
2156:
2155:
2148:
2145:
2142:
2139:
2133:
2132:
2129:
2126:
2123:
2120:
2114:
2113:
2109:
2106:
2100:
2097:
2091:
2090:
2079:
2072:
2069:
2066:
2060:
2059:
2056:
2053:
2050:
2047:
2041:
2040:
2036:
2032:
2031:
2027:
2024:
2021:
2018:
2012:
2011:
2008:
2005:
2002:
1999:
1993:
1992:
1985:
1981:
1978:
1975:
1969:
1968:
1965:
1962:Ovarian cancer
1959:
1956:
1953:
1947:
1946:
1942:
1938:
1937:
1934:
1931:
1928:
1925:
1919:
1918:
1915:
1912:
1909:
1906:
1900:
1899:
1896:
1886:
1885:Alkylates DNA.
1883:
1880:
1874:
1873:
1866:
1856:
1855:Alkylates DNA.
1853:
1850:
1848:Streptozotocin
1844:
1843:
1840:
1833:
1832:Alkylates DNA.
1830:
1827:
1821:
1820:
1817:
1814:
1811:
1808:
1802:
1801:
1798:
1795:
1792:
1789:
1783:
1782:
1779:
1776:
1775:Alkylates DNA.
1773:
1770:
1764:
1763:
1760:
1757:
1756:Alkylates DNA.
1754:
1751:
1745:
1744:
1741:
1738:
1737:Alkylates DNA.
1735:
1732:
1726:
1725:
1714:
1711:
1710:Alkylates DNA.
1708:
1705:
1699:
1698:
1691:
1669:
1668:Alkylates DNA.
1666:
1663:
1657:
1656:
1649:
1646:
1645:Alkylates DNA.
1643:
1640:
1634:
1633:
1629:
1616:
1615:Alkylates DNA.
1613:
1610:
1604:
1603:
1595:
1581:
1580:Alkylates DNA.
1578:
1575:
1569:
1568:
1564:
1542:
1541:Alkylates DNA.
1539:
1536:
1530:
1529:
1522:
1512:
1511:Alkylates DNA.
1509:
1506:
1500:
1499:
1496:
1493:
1490:
1487:
1481:
1480:
1476:
1472:
1471:
1468:
1465:
1462:
1459:
1453:
1452:
1449:
1448:Bladder cancer
1446:
1443:
1440:
1434:
1433:
1430:
1427:
1424:
1421:
1415:
1414:
1411:
1408:
1405:
1402:
1396:
1395:
1392:
1389:
1386:
1383:
1377:
1376:
1372:
1368:
1367:
1363:
1357:
1354:
1351:
1345:
1344:
1340:
1337:
1334:
1331:
1325:
1324:
1321:
1316:
1313:
1310:
1304:
1303:
1299:
1295:
1294:
1291:
1285:
1279:
1276:
1270:
1269:
1262:
1259:
1253:
1250:
1244:
1243:
1239:
1235:
1234:
1231:
1228:
1225:
1222:
1216:
1215:
1212:
1195:
1192:
1189:
1183:
1182:
1179:
1176:
1173:
1170:
1164:
1163:
1160:
1157:
1154:
1151:
1145:
1144:
1141:
1123:
1120:
1117:
1111:
1110:
1099:
1096:
1089:
1086:
1080:
1079:
1075:
1071:
1070:
1067:
1064:
1057:
1054:
1048:
1047:
1044:
1041:
1034:
1031:
1025:
1024:
1020:
1016:
1015:
1012:
987:
980:
977:
971:
970:
966:
962:
961:
958:
955:
941:
938:
932:
931:
928:
923:
913:
910:
904:
903:
900:
897:
883:
880:
874:
873:
862:
856:
842:
839:
833:
832:
820:
790:
784:
781:
775:
774:
770:
766:
765:
762:
753:
750:
747:
741:
740:
737:
734:
728:
725:
719:
718:
715:
709:
703:
700:
694:
693:
686:
676:
673:
670:
664:
663:
660:
642:
639:
636:
634:Mercaptopurine
630:
629:
614:kidney failure
610:
587:nasopharyngeal
576:
573:
570:
564:
563:
556:
518:
512:
509:
503:
502:
479:hyperglycaemia
475:
457:
450:DNA polymerase
447:
444:
438:
437:
434:
431:
425:
422:
416:
415:
408:
401:
398:
395:
389:
388:
377:conjunctivitis
361:
339:
336:DNA polymerase
333:
332:SC, IM, IV, IT
330:
324:
323:
300:
291:
288:DNA polymerase
281:
278:
272:
271:
256:
247:
241:
238:
232:
231:
228:
225:
219:
216:
210:
209:
202:
185:
180:
177:
171:
170:
159:kidney failure
152:
139:
133:
130:
124:
123:
119:
115:
114:
106:
105:
102:
99:
96:
93:
87:
86:
73:antineoplastic
65:Main article:
61:
60:
41:
39:
32:
24:
14:
13:
10:
9:
6:
4:
3:
2:
8278:
8267:
8264:
8262:
8259:
8258:
8256:
8241:
8238:
8236:
8233:
8231:
8228:
8226:
8223:
8221:
8218:
8216:
8213:
8212:
8210:
8206:
8200:
8197:
8195:
8192:
8190:
8187:
8185:
8181:
8178:
8176:
8173:
8171:
8168:
8167:
8165:
8163:
8159:
8153:
8150:
8148:
8145:
8143:
8140:
8138:
8135:
8133:
8130:
8129:
8127:
8125:
8121:
8117:
8107:
8104:
8102:
8099:
8098:
8096:
8092:
8086:
8083:
8081:
8078:
8076:
8073:
8071:
8068:
8066:
8063:
8062:
8060:
8056:
8050:
8047:
8045:
8042:
8040:
8037:
8035:
8032:
8030:
8027:
8025:
8022:
8020:
8017:
8015:
8012:
8008:
8005:
8003:
8000:
7998:
7997:oropharyngeal
7995:
7993:
7990:
7989:
7988:
7987:Head and neck
7985:
7984:
7982:
7978:
7972:
7969:
7967:
7966:Primary tumor
7964:
7962:
7959:
7957:
7954:
7952:
7949:
7947:
7944:
7943:
7941:
7937:
7931:
7928:
7926:
7923:
7921:
7918:
7916:
7913:
7912:
7910:
7908:
7907:Benign tumors
7904:
7901:
7897:
7893:
7889:
7885:
7877:
7872:
7870:
7865:
7863:
7858:
7857:
7854:
7842:
7839:
7837:
7834:
7832:
7829:
7827:
7824:
7822:
7819:
7817:
7814:
7812:
7809:
7807:
7804:
7802:
7799:
7797:
7794:
7792:
7789:
7787:
7784:
7782:
7779:
7777:
7774:
7772:
7769:
7767:
7764:
7762:
7759:
7757:
7756:Larotrectinib
7754:
7752:
7749:
7747:
7744:
7742:
7739:
7737:
7734:
7732:
7729:
7725:
7722:
7720:
7717:
7715:
7712:
7710:
7707:
7705:
7702:
7701:
7700:
7697:
7693:
7690:
7688:
7685:
7684:
7683:
7681:
7677:
7673:
7670:
7668:
7665:
7663:
7660:
7658:
7655:
7653:
7650:
7649:
7648:
7647:
7643:
7639:
7636:
7634:
7631:
7629:
7626:
7625:
7624:
7622:
7618:
7614:
7611:
7609:
7608:Ridaforolimus
7606:
7604:
7601:
7600:
7599:
7598:
7594:
7591:
7587:
7586:
7582:
7578:
7575:
7571:
7570:
7566:
7562:
7558:
7555:
7551:
7550:
7546:
7542:
7541:
7539:
7535:
7523:
7520:
7518:
7517:Pirtobrutinib
7515:
7513:
7512:Orelabrutinib
7510:
7508:
7505:
7503:
7502:Acalabrutinib
7500:
7499:
7498:
7497:
7493:
7492:
7487:
7484:
7482:
7479:
7477:
7474:
7473:
7472:
7471:
7467:
7463:
7462:
7457:
7454:
7452:
7449:
7447:
7444:
7442:
7439:
7438:
7437:
7436:
7432:
7431:
7426:
7423:
7421:
7418:
7416:
7413:
7411:
7408:
7406:
7403:
7401:
7398:
7396:
7393:
7392:
7391:
7390:
7386:
7385:
7381:
7378:
7376:
7372:
7371:
7367:
7366:
7361:
7358:
7356:
7353:
7351:
7348:
7346:
7343:
7341:
7338:
7336:
7333:
7331:
7328:
7327:
7326:
7325:
7321:
7320:
7318:
7316:
7312:
7305:
7301:
7297:
7294:
7292:
7288:
7287:
7283:
7279:
7278:Selpercatinib
7275:
7274:Repotrectinib
7271:
7267:
7263:
7262:Larotrectinib
7259:
7255:
7251:
7248:
7246:
7242:
7241:
7236:
7233:
7231:
7228:
7226:
7223:
7222:
7221:
7220:
7216:
7215:
7210:
7207:
7205:
7202:
7200:
7197:
7195:
7192:
7190:
7187:
7185:
7182:
7180:
7177:
7175:
7172:
7170:
7167:
7165:
7162:
7160:
7157:
7155:
7152:
7150:
7147:
7146:
7145:
7144:
7140:
7139:
7135:
7131:
7127:
7126:
7122:
7119:
7116:
7114:
7111:
7109:
7106:
7104:
7101:
7099:
7096:
7094:
7091:
7089:
7086:
7084:
7080:
7079:
7075:
7070:
7069:RTK class III
7067:
7066:
7061:
7058:
7056:
7053:
7051:
7048:
7047:
7046:
7045:
7040:
7039:
7035:
7032:
7030:
7027:
7025:
7022:
7020:
7017:
7015:
7012:
7010:
7007:
7005:
7002:
7000:
6997:
6995:
6992:
6990:
6987:
6985:
6982:
6980:
6977:
6975:
6971:
6970:
6965:
6962:
6961:
6959:
6957:
6953:
6950:
6947:
6943:
6933:
6930:
6928:
6925:
6923:
6920:
6918:
6915:
6913:
6910:
6908:
6905:
6903:
6900:
6898:
6895:
6893:
6890:
6888:
6885:
6883:
6880:
6878:
6875:
6873:
6870:
6868:
6865:
6863:
6860:
6858:
6855:
6853:
6852:Pembrolizumab
6850:
6848:
6845:
6843:
6840:
6838:
6835:
6833:
6830:
6828:
6825:
6823:
6820:
6818:
6817:Mogamulizumab
6815:
6813:
6810:
6808:
6805:
6803:
6800:
6798:
6795:
6793:
6790:
6788:
6785:
6783:
6780:
6778:
6775:
6773:
6770:
6768:
6765:
6763:
6760:
6758:
6755:
6753:
6750:
6748:
6745:
6743:
6740:
6738:
6735:
6733:
6730:
6728:
6725:
6722:
6718:
6715:
6713:
6710:
6709:
6707:
6703:
6696:
6692:
6691:
6686:
6683:
6682:
6678:
6674:
6673:
6668:
6664:
6663:
6658:
6655:
6653:
6650:
6648:
6645:
6643:
6640:
6638:
6637:Mosunetuzumab
6635:
6633:
6630:
6628:
6624:
6623:
6618:
6617:Mosunetuzumab
6614:
6610:
6606:
6605:
6600:
6597:
6596:
6594:
6592:
6588:
6584:
6577:
6573:
6572:
6568:
6565:
6562:
6560:
6556:
6555:
6551:
6550:
6548:
6544:
6537:
6534:
6532:
6529:
6526:
6522:
6518:
6514:
6513:
6509:
6506:
6503:
6501:
6497:
6496:
6491:
6488:
6487:
6485:
6483:
6479:
6476:
6473:
6470:
6466:
6461:
6457:
6453:
6446:
6441:
6439:
6434:
6432:
6427:
6426:
6423:
6407:
6405:
6402:
6401:
6399:
6396:
6393:
6390:
6388:
6385:
6384:
6380:
6370:
6367:
6365:
6362:
6360:
6357:
6355:
6352:
6350:
6347:
6345:
6342:
6340:
6337:
6335:
6332:
6330:
6327:
6325:
6322:
6320:
6317:
6315:
6312:
6310:
6307:
6305:
6302:
6300:
6297:
6295:
6292:
6289:
6286:
6284:
6280:
6279:
6275:
6273:
6272:Tabelecleucel
6270:
6268:
6265:
6263:
6260:
6258:
6255:
6253:
6250:
6248:
6245:
6243:
6240:
6238:
6235:
6233:
6232:Lurbinectedin
6230:
6228:
6225:
6223:
6220:
6218:
6215:
6213:
6210:
6208:
6205:
6203:
6200:
6198:
6195:
6193:
6190:
6188:
6185:
6183:
6180:
6178:
6175:
6173:
6170:
6168:
6165:
6163:
6160:
6158:
6155:
6153:
6150:
6148:
6145:
6143:
6140:
6138:
6135:
6133:
6130:
6128:
6125:
6123:
6120:
6118:
6115:
6112:
6108:
6104:
6103:
6099:
6097:
6094:
6092:
6089:
6087:
6084:
6083:
6081:
6077:
6070:
6066:
6065:
6061:
6058:
6054:
6053:
6049:
6046:
6042:
6041:
6037:
6036:
6034:
6032:
6028:
6021:
6018:
6016:
6013:
6011:
6008:
6006:
6003:
6001:
5997:
5995:
5991:
5988:
5985:
5983:
5980:
5978:
5975:
5973:
5970:
5968:
5964:
5963:
5959:
5956:
5953:
5951:
5948:
5946:
5943:
5940:
5938:
5934:
5933:
5929:
5926:
5922:
5921:
5917:
5914:
5910:
5909:
5905:
5902:
5898:
5897:
5893:
5889:
5886:
5884:
5881:
5879:
5876:
5874:
5871:
5870:
5869:
5868:
5864:
5861:
5858:
5856:
5853:
5851:
5848:
5846:
5843:
5841:
5837:
5836:
5833:
5829:
5826:
5822:
5821:
5817:
5816:
5814:
5812:
5808:
5805:
5801:
5794:
5791:
5789:
5786:
5784:
5781:
5779:
5775:
5774:
5770:
5768:
5765:
5763:
5760:
5758:
5755:
5753:
5750:
5749:
5747:
5745:
5741:
5737:
5722:
5719:
5717:
5714:
5712:
5709:
5707:
5703:
5700:
5699:
5697:
5695:
5694:Intercalation
5691:
5684:
5681:
5679:
5676:
5674:
5670:
5669:
5665:
5663:
5660:
5658:
5655:
5653:
5650:
5647:
5643:
5642:
5638:
5636:
5633:
5632:
5630:
5628:
5624:
5618:
5615:
5613:
5610:
5608:
5605:
5603:
5602:Dicycloplatin
5600:
5598:
5595:
5593:
5590:
5589:
5587:
5585:
5581:
5575:
5572:
5570:
5567:
5565:
5562:
5560:
5557:
5555:
5551:
5550:
5546:
5543:
5541:
5537:
5534:
5532:
5528:
5527:
5524:
5521:
5519:
5516:
5514:
5511:
5508:
5504:
5501:
5499:
5496:
5494:
5491:
5489:
5485:
5484:
5481:
5478:
5476:
5475:Prednimustine
5473:
5470:
5466:
5463:
5461:
5458:
5455:
5452:
5450:
5446:
5443:
5441:
5438:
5436:
5433:
5431:
5427:
5426:
5424:
5422:
5418:
5415:
5412:
5407:
5403:
5393:
5390:
5388:
5385:
5383:
5380:
5378:
5375:
5372:
5369:
5367:
5364:
5362:
5358:
5357:
5353:
5350:
5347:
5345:
5342:
5340:
5337:
5335:
5332:
5330:
5327:
5325:
5322:
5319:
5315:
5312:
5310:
5307:
5305:
5301:
5300:
5296:
5295:
5293:
5291:
5290:Intercalation
5287:
5283:
5276:
5273:
5271:
5267:
5266:
5262:
5261:
5259:
5257:
5253:
5246:
5243:
5241:
5238:
5236:
5233:
5231:
5228:
5226:
5223:
5221:
5218:
5216:
5213:
5211:
5208:
5206:
5203:
5201:
5198:
5196:
5192:
5191:
5187:
5186:
5184:
5182:
5178:
5175:
5172:
5167:
5163:
5152:
5148:
5147:
5143:
5142:
5140:
5138:
5134:
5127:
5124:
5122:
5118:
5117:
5113:
5112:
5108:
5104:
5103:
5099:
5098:
5094:
5093:+daunorubicin
5091:
5087:
5086:
5082:
5081:
5077:
5073:
5070:
5068:
5065:
5063:
5060:
5058:
5057:Doxifluridine
5055:
5053:
5050:
5048:
5044:
5043:
5039:
5038:
5036:
5034:
5030:
5023:
5020:
5018:
5014:
5013:
5009:
5007:
5006:Rabacfosadine
5004:
5002:
4999:
4996:
4993:
4991:
4988:
4986:
4982:
4981:
4977:
4973:
4972:
4968:
4964:
4963:
4959:
4958:
4956:
4954:
4950:
4943:
4940:
4938:
4934:
4933:
4929:
4926:
4923:
4921:
4918:
4916:
4913:
4911:
4907:
4906:
4902:
4901:
4899:
4897:
4893:
4890:
4887:
4882:
4876:
4873:
4869:
4865:
4854:
4850:
4849:
4845:
4842:
4839:
4837:
4834:
4832:
4829:
4827:
4824:
4822:
4819:
4817:
4813:
4812:
4808:
4807:
4805:
4801:
4794:
4791:
4789:
4786:
4784:
4781:
4779:
4776:
4774:
4770:
4769:
4765:
4764:
4762:
4759:
4754:
4751:
4748:
4743:
4739:
4735:
4730:
4726:
4722:
4714:
4709:
4707:
4702:
4700:
4695:
4694:
4691:
4672:
4668:
4662:
4659:
4646:
4642:
4636:
4633:
4628:
4624:
4619:
4614:
4610:
4606:
4602:
4598:
4594:
4587:
4584:
4571:
4567:
4561:
4558:
4545:
4541:
4535:
4532:
4522:
4518:
4514:
4510:
4509:"Trabectedin"
4504:
4501:
4491:
4487:
4483:
4479:
4473:
4470:
4460:
4456:
4452:
4448:
4442:
4439:
4429:
4425:
4421:
4417:
4411:
4408:
4395:
4391:
4384:
4382:
4380:
4378:
4376:
4374:
4372:
4370:
4368:
4364:
4354:
4350:
4346:
4342:
4336:
4333:
4323:
4319:
4315:
4311:
4305:
4302:
4289:
4285:
4279:
4276:
4271:
4267:
4262:
4257:
4253:
4249:
4245:
4241:
4237:
4233:
4229:
4222:
4219:
4214:
4210:
4205:
4200:
4196:
4192:
4188:
4184:
4180:
4173:
4170:
4165:
4161:
4157:
4153:
4149:
4145:
4141:
4137:
4133:
4129:
4122:
4119:
4114:
4110:
4106:
4102:
4098:
4094:
4087:
4084:
4079:
4075:
4071:
4067:
4063:
4059:
4055:
4051:
4044:
4041:
4036:
4032:
4028:
4024:
4020:
4016:
4012:
4008:
4004:
4000:
3993:
3990:
3985:
3979:
3975:
3971:
3967:
3960:
3957:
3944:
3943:
3935:
3932:
3927:
3921:
3917:
3910:
3908:
3906:
3902:
3897:
3891:
3887:
3886:
3878:
3875:
3870:
3864:
3859:
3858:
3849:
3847:
3845:
3841:
3836:
3830:
3826:
3819:
3817:
3815:
3813:
3811:
3809:
3807:
3803:
3796:
3782:
3779:
3773:
3770:
3764:
3761:
3755:
3752:
3748:
3744:
3741:
3739:
3733:
3729:
3725:
3722:
3719:
3716:
3713:
3711:
3708:
3707:
3703:
3699:
3696:
3693:
3690:
3688:
3685:
3684:
3680:
3677:
3674:
3671:
3667:
3664:
3663:
3659:
3655:
3652:
3648:
3645:
3642:
3639:
3638:
3634:
3631:
3627:
3624:
3621:
3619:
3616:
3615:
3610:
3608:
3605:
3602:
3599:
3596:
3594:
3591:
3590:
3587:
3581:
3577:
3574:
3571:
3568:
3566:
3563:
3562:
3558:
3554:
3550:
3547:
3544:
3540:
3536:
3533:
3530:
3528:
3525:
3524:
3520:
3517:
3514:
3511:
3509:
3506:
3505:
3501:
3498:
3495:
3492:
3490:
3487:
3486:
3483:
3477:
3472:
3469:
3465:
3462:
3459:
3457:
3454:
3453:
3449:
3446:
3443:
3440:
3438:
3435:
3434:
3429:
3427:
3424:
3421:
3417:
3413:
3409:
3405:
3402:
3400:
3397:
3396:
3393:
3387:
3383:
3378:
3375:
3372:
3368:
3365:
3362:
3360:
3357:
3356:
3352:
3348:
3345:
3342:
3339:
3337:
3334:
3333:
3330:(very rare).
3329:
3324:
3320:
3317:
3314:
3310:
3307:
3304:
3302:
3299:
3298:
3294:
3291:
3288:
3285:
3283:
3280:
3279:
3275:
3272:
3269:
3265:
3262:
3259:
3257:
3254:
3253:
3250:
3248:2.4 Retinoids
3244:
3239:
3236:
3233:
3230:
3228:
3225:
3224:
3219:
3216:
3213:
3210:
3208:
3205:
3204:
3201:
3198:
3191:
3187:
3184:
3181:
3178:
3176:
3173:
3172:
3168:
3163:
3160:
3157:
3154:
3152:
3149:
3148:
3143:
3140:
3136:
3133:
3130:
3128:
3125:
3124:
3120:
3117:
3116:Myelofibrosis
3114:
3111:
3107:
3104:
3101:
3099:
3096:
3095:
3091:
3088:
3085:
3082:
3080:
3077:
3076:
3072:
3069:
3066:
3063:
3061:
3058:
3057:
3052:
3049:
3046:
3042:
3038:
3034:
3030:
3027:
3025:
3022:
3021:
3017:
3013:
3010:
3007:
3004:
3002:
2999:
2998:
2994:
2991:
2988:
2985:
2982:
2979:
2977:
2974:
2973:
2969:
2964:
2961:
2958:
2955:
2953:
2950:
2949:
2945:
2941:
2937:
2934:
2931:
2928:
2925:
2922:
2920:
2917:
2916:
2911:
2908:
2905:
2902:
2899:
2897:
2894:
2893:
2889:
2885:
2881:
2878:
2874:
2870:
2867:
2863:
2859:
2855:
2852:
2850:
2847:
2846:
2842:
2838:
2835:
2832:
2829:
2827:
2824:
2823:
2819:
2814:
2812:
2809:
2806:
2803:
2800:
2798:
2795:
2794:
2790:
2789:polycythaemia
2786:
2784:
2781:
2778:
2775:
2773:
2770:
2769:
2765:
2762:
2759:
2755:
2752:
2749:
2747:
2744:
2743:
2739:
2736:
2733:
2729:
2725:
2722:
2719:
2717:
2714:
2713:
2710:
2704:
2700:
2697:
2694:
2690:
2687:
2685:
2682:
2681:
2677:
2673:
2669:
2665:
2661:
2658:
2655:
2651:
2647:
2644:
2642:
2639:
2638:
2633:
2631:
2627:
2623:
2619:
2615:
2612:
2608:
2605:
2603:
2600:
2599:
2595:
2592:
2589:
2586:
2583:
2581:
2578:
2577:
2573:
2570:
2566:
2562:
2558:
2554:
2551:
2548:
2545:
2543:
2542:Pembrolizumab
2540:
2539:
2535:
2532:
2529:
2526:
2524:
2521:
2520:
2516:
2514:
2511:
2508:
2504:
2501:
2499:
2496:
2495:
2490:
2487:
2483:
2479:
2475:
2471:
2467:
2463:
2459:
2455:
2451:
2447:
2444:
2442:
2438:
2434:
2431:
2428:
2426:
2423:
2422:
2418:
2415:
2412:
2409:
2406:
2404:
2401:
2400:
2396:
2393:
2390:
2386:
2383:
2380:
2378:
2375:
2374:
2370:
2367:
2364:
2361:
2358:
2356:
2353:
2352:
2348:
2345:
2341:
2338:
2335:
2332:
2330:
2327:
2326:
2322:
2319:
2316:
2313:
2310:
2308:
2305:
2304:
2299:
2296:
2293:
2290:
2287:
2285:
2282:
2281:
2277:
2273:
2270:
2267:
2264:
2261:
2258:
2256:
2253:
2252:
2249:
2243:
2240:
2234:
2230:
2227:
2224:
2221:
2218:
2216:
2213:
2212:
2208:
2205:
2202:
2199:
2196:
2195:
2191:
2188:
2185:
2182:
2180:
2177:
2176:
2172:
2169:
2166:
2163:
2161:
2158:
2157:
2153:
2149:
2146:
2143:
2140:
2138:
2135:
2134:
2130:
2127:
2124:
2121:
2119:
2116:
2115:
2110:
2107:
2104:
2101:
2098:
2096:
2093:
2092:
2088:
2084:
2080:
2077:
2073:
2070:
2067:
2065:
2062:
2061:
2057:
2054:
2051:
2048:
2046:
2043:
2042:
2039:
2033:
2028:
2025:
2022:
2019:
2017:
2014:
2013:
2009:
2006:
2003:
2000:
1998:
1995:
1994:
1990:
1986:
1982:
1979:
1976:
1974:
1971:
1970:
1966:
1963:
1960:
1957:
1954:
1952:
1949:
1948:
1945:
1939:
1935:
1932:
1929:
1926:
1924:
1921:
1920:
1916:
1913:
1910:
1907:
1905:
1902:
1901:
1897:
1894:
1890:
1887:
1884:
1881:
1879:
1876:
1875:
1871:
1870:hypoglycaemia
1867:
1864:
1860:
1857:
1854:
1851:
1849:
1846:
1845:
1841:
1838:
1834:
1831:
1828:
1826:
1823:
1822:
1818:
1815:
1812:
1809:
1807:
1804:
1803:
1799:
1796:
1793:
1790:
1788:
1787:Lurbinectedin
1785:
1784:
1780:
1777:
1774:
1771:
1769:
1766:
1765:
1761:
1758:
1755:
1752:
1750:
1747:
1746:
1742:
1739:
1736:
1733:
1731:
1728:
1727:
1723:
1719:
1715:
1712:
1709:
1706:
1704:
1701:
1700:
1696:
1692:
1690:
1686:
1682:
1678:
1674:
1670:
1667:
1664:
1662:
1659:
1658:
1654:
1650:
1647:
1644:
1641:
1639:
1636:
1635:
1630:
1628:
1624:
1620:
1617:
1614:
1611:
1609:
1606:
1605:
1601:
1596:
1593:
1589:
1585:
1582:
1579:
1576:
1574:
1571:
1570:
1565:
1563:
1559:
1555:
1554:myelofibrosis
1551:
1547:
1543:
1540:
1537:
1535:
1532:
1531:
1527:
1523:
1520:
1516:
1513:
1510:
1507:
1505:
1502:
1501:
1497:
1494:
1491:
1488:
1486:
1483:
1482:
1479:
1473:
1469:
1466:
1463:
1460:
1458:
1455:
1454:
1450:
1447:
1444:
1441:
1439:
1436:
1435:
1431:
1428:
1425:
1422:
1420:
1417:
1416:
1412:
1409:
1406:
1403:
1401:
1398:
1397:
1393:
1390:
1387:
1384:
1382:
1379:
1378:
1375:
1369:
1364:
1362:
1358:
1355:
1352:
1350:
1347:
1346:
1341:
1338:
1335:
1332:
1330:
1327:
1326:
1322:
1320:
1317:
1314:
1311:
1309:
1306:
1305:
1302:
1296:
1292:
1290:
1289:neuroblastoma
1286:
1283:
1280:
1277:
1275:
1272:
1271:
1267:
1263:
1260:
1257:
1254:
1251:
1249:
1246:
1245:
1242:
1236:
1232:
1229:
1226:
1223:
1221:
1218:
1217:
1213:
1211:
1207:
1203:
1199:
1196:
1193:
1190:
1188:
1185:
1184:
1180:
1177:
1174:
1171:
1169:
1166:
1165:
1161:
1158:
1155:
1152:
1150:
1147:
1146:
1142:
1140:
1136:
1135:neuroblastoma
1132:
1128:
1127:Wilms' tumour
1124:
1121:
1118:
1116:
1113:
1112:
1108:
1104:
1100:
1097:
1094:
1090:
1087:
1085:
1082:
1081:
1078:
1072:
1068:
1065:
1062:
1058:
1055:
1053:
1050:
1049:
1045:
1042:
1039:
1035:
1032:
1030:
1027:
1026:
1023:
1017:
1013:
1011:
1007:
1003:
1002:myelofibrosis
999:
995:
991:
988:
985:
981:
978:
976:
973:
972:
969:
963:
959:
956:
953:
949:
945:
942:
939:
937:
934:
933:
929:
927:
924:
921:
917:
914:
911:
909:
906:
905:
901:
898:
895:
891:
887:
884:
881:
879:
876:
875:
871:
867:
863:
860:
857:
854:
850:
846:
843:
840:
838:
835:
834:
830:
826:
821:
818:
814:
810:
806:
802:
798:
797:breast cancer
794:
791:
788:
785:
782:
780:
777:
776:
773:
767:
763:
761:
757:
754:
751:
748:
746:
743:
742:
738:
735:
732:
729:
726:
724:
721:
720:
716:
713:
710:
707:
704:
701:
699:
696:
695:
691:
687:
684:
680:
677:
674:
671:
669:
666:
665:
661:
658:
654:
650:
646:
643:
640:
637:
635:
632:
631:
627:
623:
619:
615:
611:
608:
604:
600:
596:
592:
588:
584:
580:
577:
574:
571:
569:
566:
565:
561:
557:
554:
550:
546:
542:
538:
537:head and neck
534:
530:
526:
522:
519:
516:
513:
510:
508:
505:
504:
500:
496:
492:
488:
484:
480:
476:
473:
469:
465:
461:
458:
455:
451:
448:
445:
443:
440:
439:
435:
432:
429:
426:
423:
421:
418:
417:
413:
409:
406:
402:
399:
396:
394:
391:
390:
386:
382:
378:
374:
370:
366:
362:
359:
355:
351:
347:
343:
340:
337:
334:
331:
329:
326:
325:
321:
317:
313:
309:
305:
301:
299:
295:
292:
289:
285:
282:
279:
277:
274:
273:
269:
265:
261:
257:
255:
251:
248:
245:
242:
239:
237:
234:
233:
229:
226:
223:
220:
217:
215:
212:
211:
207:
203:
201:
197:
193:
189:
186:
184:
181:
178:
176:
173:
172:
168:
164:
160:
156:
153:
151:
147:
143:
140:
137:
134:
131:
129:
126:
125:
122:
116:
113:
107:
103:
100:
97:
94:
92:
89:
88:
83:
80:
78:
74:
68:
57:
45:
40:
31:
30:
27:
19:
8266:Chemotherapy
7882:Overview of
7796:Pexidartinib
7781:Odronextamab
7751:Gilteritinib
7731:Cabozantinib
7678:
7644:
7619:
7613:Temsirolimus
7595:
7579:
7561:proapoptotic
7559:
7543:
7522:Zanubrutinib
7494:
7464:
7433:
7410:Lestaurtinib
7389:Janus kinase
7387:
7368:
7322:
7315:Non-receptor
7296:Cabozantinib
7289:
7258:Infigratinib
7243:
7217:
7159:Fruquintinib
7141:
7134:Gilteritinib
7130:Lestaurtinib
7123:
7072:
7041:
7014:Mobocertinib
6979:Aumolertinib
6967:
6932:Tremelimumab
6917:Tislelizumab
6872:Retifanlimab
6747:Blinatumomab
6717:Atezolizumab
6688:
6670:
6660:
6642:Obinutuzumab
6620:
6602:
6569:
6552:
6510:
6493:
6319:Tazemetostat
6283:Alitretinoin
6276:
6187:Estramustine
6167:Elsamitrucin
6157:Eflornithine
6111:Pegaspargase
6107:Asparaginase
6100:
6069:Testolactone
6062:
6050:
6038:
5992:
5977:Panobinostat
5960:
5930:
5918:
5906:
5894:
5865:
5830:
5818:
5771:
5767:Padeliporfin
5706:Dactinomycin
5702:Streptomyces
5683:Temozolomide
5678:Mitozolomide
5666:
5657:Mitobronitol
5646:Procarbazine
5639:
5627:Nonclassical
5552:
5529:
5523:Streptozocin
5488:Nitrosoureas
5486:
5460:Chlorambucil
5454:Trofosfamide
5440:Chlormethine
5435:Bendamustine
5428:
5366:Mitoxantrone
5361:Losoxantrone
5354:
5314:Daunorubicin
5297:
5263:
5200:Camptothecin
5188:
5144:
5114:
5100:
5083:
5067:Fluorouracil
5047:Capecitabine
5040:
5010:
4974:
4960:
4930:
4925:Pralatrexate
4915:Methotrexate
4903:
4846:
4809:
4766:
4675:. Retrieved
4670:
4661:
4649:. Retrieved
4644:
4635:
4600:
4596:
4586:
4574:. Retrieved
4569:
4560:
4548:. Retrieved
4543:
4534:
4524:, retrieved
4512:
4503:
4493:, retrieved
4481:
4472:
4462:, retrieved
4450:
4441:
4431:, retrieved
4419:
4410:
4398:. Retrieved
4393:
4356:, retrieved
4344:
4335:
4325:, retrieved
4313:
4304:
4292:. Retrieved
4287:
4278:
4235:
4231:
4221:
4186:
4182:
4172:
4134:(1): 75–81.
4131:
4127:
4121:
4099:(1): 23–38.
4096:
4092:
4086:
4053:
4049:
4043:
4002:
3998:
3992:
3965:
3959:
3947:. Retrieved
3941:
3934:
3915:
3884:
3877:
3856:
3824:
3781:
3772:
3763:
3754:
3746:
3737:
3735:
3731:
3641:Asparaginase
3583:
3489:Panobinostat
3479:
3437:Pomalidomide
3399:Lenalidomide
3389:
3381:
3376:
3343:RAR agonist.
3336:Tamibarotene
3322:
3318:
3301:Isotretinoin
3289:RXR agonist.
3256:Alitretinoin
3246:
3227:Temsirolimus
3193:
2791:(uncommon).
2706:
2482:liver cancer
2474:colon cancer
2272:Pancytopenia
2245:
2236:
2215:Procarbazine
2137:Estramustine
2118:Dactinomycin
2035:
1984:osteosarcoma
1941:
1908:IV, topical
1878:Temozolomide
1720:(uncommon),
1638:Chlormethine
1608:Chlorambucil
1526:hypokalaemia
1504:Bendamustine
1475:
1371:
1300:1.07 Taxanes
1298:
1238:
1187:Mitoxantrone
1084:Daunorubicin
1074:
1019:
965:
954:inhibitors.
936:Trimetrexate
896:inhibitors.
878:Pralatrexate
825:osteoporosis
809:osteosarcoma
779:Methotrexate
769:
507:Fluorouracil
485:(uncommon),
428:Fluorouracil
380:
373:pericarditis
365:pancreatitis
320:pancreatitis
314:(uncommon),
304:hypokalaemia
222:Fluorouracil
175:Capecitabine
167:hypokalaemia
118:
109:
70:
67:Chemotherapy
54:January 2021
51:
43:
26:
8230:Cancer pain
8170:Cancer cell
7915:Hyperplasia
7826:Tebentafusp
7806:Regorafenib
7801:Quizartinib
7791:Pemigatinib
7771:Midostaurin
7746:Erdafitinib
7741:Entrectinib
7724:Parsaclisib
7672:Trilaciclib
7662:Palbociclib
7657:Dalpiciclib
7652:Abemaciclib
7554:Aflibercept
7481:Entrectinib
7451:Selumetinib
7446:Cobimetinib
7441:Binimetinib
7425:Ruxolitinib
7415:Momelotinib
7395:Baricitinib
7293:inhibitors:
7270:Pralsetinib
7266:Pemigatinib
7254:Futibatinib
7250:Entrectinib
7247:inhibitors:
7179:Regorafenib
7083:Avapritinib
7029:Rociletinib
7024:Osimertinib
6989:Dacomitinib
6927:Toripalimab
6912:Teclistamab
6902:Talquetamab
6897:Tafasitamab
6892:Sugemalimab
6887:Serplulimab
6877:Sabatolimab
6867:Ramucirumab
6862:Prolgolimab
6832:Necitumumab
6787:Epcoritamab
6767:Dostarlimab
6757:Daratumumab
6712:Amivantamab
6677:Alemtuzumab
6667:Brentuximab
6657:Tositumomab
6632:Ibritumomab
6613:Elranatamab
6576:Bevacizumab
6564:Edrecolomab
6559:Catumaxomab
6521:Trastuzumab
6505:Panitumumab
6394:from market
6364:Vorasidenib
6344:Trabectedin
6329:Tiazofurine
6324:Tebentafusp
6309:Tagraxofusp
6267:Plitidepsin
6237:Mitoguazone
6177:Epacadostat
6147:Demecolcine
6091:Aflibercept
6064:Sex steroid
5937:Fuzuloparib
5878:Carfilzomib
5850:Palbociclib
5840:Abemaciclib
5793:Verteporfin
5757:Efaproxiral
5673:Dacarbazine
5635:Altretamine
5617:Satraplatin
5612:Oxaliplatin
5592:Carboplatin
5569:Triaziquone
5540:Mannosulfan
5518:Ranimustine
5498:Fotemustine
5339:Pirarubicin
5324:Doxorubicin
5318:+cytarabine
5304:Aclarubicin
5265:Podophyllum
5190:Camptotheca
5121:Azacitidine
5107:Gemcitabine
5062:Floxuridine
4995:Fludarabine
4990:Clofarabine
4976:Halogenated
4967:Pentostatin
4942:Raltitrexed
4910:Aminopterin
4853:Ixabepilone
4848:Epothilones
4816:Cabazitaxel
4793:Vinorelbine
4778:Vincristine
4773:Vinblastine
4758:microtubule
4294:11 February
3710:Vemurafenib
3456:Thalidomide
3363:PO, topical
3305:PO, topical
3286:PO, topical
3098:Ruxolitinib
3079:Regorafenib
2942:(rare) and
2746:Aflibercept
2684:Trastuzumab
2641:Tositumomab
2557:lung cancer
2523:Panitumumab
2450:lung cancer
2284:Bevacizumab
2255:Alemtuzumab
2197:Plicamycin
2160:Ixabepilone
2083:scleroderma
2045:Altretamine
2016:Oxaliplatin
1951:Carboplatin
1923:Trabectedin
1730:Fotemustine
1703:Dacarbazine
1642:IV, topical
1485:Altretamine
1457:Vinorelbine
1400:Vincristine
1381:Vinblastine
1308:Cabazitaxel
1115:Doxorubicin
908:Raltitrexed
855:inhibitors.
731:Thymidylate
698:Pentostatin
568:Gemcitabine
560:anaphylaxis
541:oesophageal
511:IV, Topical
497:(rare) and
483:pneumonitis
442:Fludarabine
420:Floxuridine
369:anaphylaxis
322:(uncommon)
276:Clofarabine
266:(rare) and
128:Azacitidine
101:Indications
8255:Categories
8175:Carcinogen
8039:Urogenital
7980:Topography
7961:Metastasis
7925:Pseudocyst
7899:Conditions
7841:Venetoclax
7836:Vandetanib
7811:Ripretinib
7776:Nintedanib
7761:Lenvatinib
7736:Capmatinib
7719:Idelalisib
7709:Copanlisib
7682:inhibitors
7667:Ribociclib
7638:Vismodegib
7623:inhibitors
7603:Everolimus
7569:prohibitin
7486:Lorlatinib
7476:Crizotinib
7456:Trametinib
7420:Pacritinib
7405:Filgotinib
7400:Fedratinib
7304:Crizotinib
7300:Capmatinib
7282:Vandetanib
7230:Brigatinib
7209:Vandetanib
7169:Nintedanib
7164:Lenvatinib
7103:Ripretinib
7034:Vandetanib
7009:Lazertinib
6984:Brigatinib
6907:Tarlatamab
6842:Olaratumab
6802:Isatuximab
6797:Ipilimumab
6777:Elotuzumab
6772:Durvalumab
6752:Cemiplimab
6742:Bermekimab
6732:Axatilimab
6647:Ofatumumab
6627:Glofitamab
6609:Glofitamab
6517:Pertuzumab
6359:Verdinexor
6354:Venetoclax
6257:Oblimersen
6252:Navitoclax
6227:Lucanthone
6222:Lonidamine
6212:Lifileucel
6207:Ivosidenib
6202:Imetelstat
6172:Enasidenib
6162:Elesclomol
6127:Bexarotene
6122:Belzutifan
6057:Bexarotene
6045:Atrasentan
6020:Umbralisib
6015:Idelalisib
6005:Copanlisib
5987:Vorinostat
5982:Romidepsin
5972:Entinostat
5967:Belinostat
5925:Masoprocol
5913:Tiazofurin
5901:Anagrelide
5873:Bortezomib
5860:Seliciclib
5855:Ribociclib
5835:inhibitors
5825:Tipifarnib
5788:Temoporfin
5783:Talaporfin
5721:Plicamycin
5716:Mitomycins
5662:Pipobroman
5641:Hydrazines
5607:Nedaplatin
5559:Carboquone
5554:Aziridines
5545:Treosulfan
5493:Carmustine
5480:Uramustine
5449:Ifosfamide
5421:Alkylating
5382:Bisantrene
5371:Pixantrone
5344:Valrubicin
5334:Idarubicin
5329:Epirubicin
5275:Teniposide
5230:Lurtotecan
5225:Irinotecan
5126:Decitabine
5090:Cytarabine
5033:Pyrimidine
5022:Tioguanine
5012:Thiopurine
5001:Nelarabine
4985:Cladribine
4937:Pemetrexed
4920:Pemetrexed
4896:Folic acid
4836:Paclitaxel
4788:Vinflunine
4677:9 February
4651:9 February
4576:9 February
4550:9 February
4526:2024-04-11
4495:2024-04-11
4478:"Thiotepa"
4464:2024-04-10
4433:2024-04-10
4400:7 February
4358:2024-04-11
4327:2024-04-11
3949:8 February
3797:References
3629:leukaemia.
3603:inhibitor.
3593:Anagrelide
3565:Vorinostat
3541:(orphan),
3508:Romidepsin
3384:Erythema.
3282:Bexarotene
3266:(RAR) and
3207:Everolimus
3199:inhibitors
3175:Vandetanib
3112:inhibitor.
2986:inhibitor.
2929:inhibitor.
2906:inhibitor.
2826:Crizotinib
2760:inhibitor.
2734:inhibitor.
2590:inhibitor.
2580:Pertuzumab
2498:Ofatumumab
2403:Ipilimumab
2339:inhibitor.
2317:inhibitor.
2294:inhibitor.
2105:inhibitor.
2103:Proteasome
2095:Bortezomib
1997:Nedaplatin
1749:Ifosfamide
1600:thrombosis
1573:Carmustine
1470:As above.
1438:Vinflunine
1349:Paclitaxel
1293:As above.
1284:inhibitor.
1274:Teniposide
1258:inhibitor.
1233:As above.
1220:Valrubicin
1214:As above.
1181:As above.
1168:Idarubicin
1162:As above.
1149:Epirubicin
1143:As above.
1029:Irinotecan
922:inhibitor.
837:Pemetrexed
789:inhibitor.
745:Tioguanine
708:inhibitor.
668:Nelarabine
529:colorectal
517:inhibitor.
456:inhibitor.
393:Decitabine
381:High dose:
328:Cytarabine
290:inhibitor.
236:Cladribine
192:colorectal
8194:Oncovirus
8184:oncogenes
8137:Ann Arbor
8080:Papilloma
8065:Carcinoma
8058:Histology
8002:laryngeal
7946:Dysplasia
7930:Hamartoma
7831:Tepotinib
7821:Sunitinib
7816:Sorafenib
7786:Pazopanib
7766:Masitinib
7714:Duvelisib
7704:Alpelisib
7692:Sotorasib
7687:Adagrasib
7633:Sonidegib
7628:Glasdegib
7574:Adipotide
7507:Ibrutinib
7380:Dasatinib
7375:Bosutinib
7360:Radotinib
7355:Ponatinib
7350:Nilotinib
7340:Dasatinib
7335:Bosutinib
7330:Asciminib
7298:(VEGFR),
7256:(FGFR2),
7235:Ceritinib
7225:Alectinib
7204:Toceranib
7199:Tivozanib
7194:Sunitinib
7189:Sorafenib
7184:Semaxanib
7174:Pazopanib
7154:Cediranib
7118:Toceranib
7113:Sunitinib
7108:Sorafenib
7098:Pazopanib
7093:Masitinib
7060:Tucatinib
7055:Neratinib
7050:Lapatinib
7019:Olmutinib
6999:Gefitinib
6994:Erlotinib
6969:HER1/EGFR
6837:Nivolumab
6827:Naxitamab
6652:Rituximab
6500:Cetuximab
6495:HER1/EGFR
6404:Phase III
6392:Withdrawn
6369:Vosaroxin
6349:Veliparib
6304:Sotorasib
6294:Selinexor
6288:Tretinoin
6278:Retinoids
6192:Glasdegib
6137:Celecoxib
6086:Adagrasib
6010:Duvelisib
6000:Alpelisib
5955:Rucaparib
5942:Niraparib
5883:Oprozomib
5845:Alvocidib
5711:Bleomycin
5668:Triazenes
5652:Etoglucid
5597:Cisplatin
5513:Nimustine
5507:Semustine
5503:Lomustine
5465:Melphalan
5392:Menogaril
5387:Crisnatol
5377:Amsacrine
5349:Zorubicin
5309:Amrubicin
5270:Etoposide
5245:Topotecan
5240:Silatecan
5235:Rubitecan
5220:Gimatecan
5205:Cositecan
5195:Belotecan
4871:inhibitor
4841:Tesetaxel
4831:Ortataxel
4826:Larotaxel
4821:Docetaxel
4783:Vindesine
4252:1469-493X
4148:1742-5255
4070:0012-6667
4019:1354-3784
3650:survival.
3572:As above.
3534:As above.
3527:Valproate
3463:As above.
3444:As above.
3369:Acne and
3359:Tretinoin
3151:Sunitinib
3127:Sorafenib
3060:Ponatinib
3024:Pazopanib
3001:Nilotinib
2976:Lapatinib
2919:Gefitinib
2896:Erlotinib
2849:Dasatinib
2797:Bosutinib
2695:antibody.
2613:antibody.
2602:Rituximab
2509:antibody.
2425:Nivolumab
2329:Denosumab
2307:Cetuximab
2179:Mitomycin
2064:Bleomycin
1973:Cisplatin
1825:Melphalan
1768:Lomustine
1594:(topical)
1464:As above.
1445:As above.
1426:As above.
1419:Vindesine
1407:As above.
1356:As above.
1336:As above.
1329:Docetaxel
1248:Etoposide
1227:As above.
1194:As above.
1175:As above.
1156:As above.
1122:As above.
1059:Inhibits
1052:Topotecan
1036:Inhibits
603:lymphomas
430:analogue.
354:lymphomas
8215:Research
8075:Blastoma
7892:oncology
7621:hedgehog
7583:against
7581:exotoxin
7547:against
7496:Bruton's
7345:Imatinib
7268:(FGFR),
7264:(NTRK),
7149:Axitinib
7088:Axitinib
7044:HER2/neu
7004:Icotinib
6974:Afatinib
6948:("-nib")
6727:Avelumab
6599:lymphoid
6591:lymphoma
6587:Leukemia
6512:HER2/neu
6474:("-mab")
6242:Mitotane
6182:Eribulin
5950:Olaparib
5888:Ixazomib
5564:Thiotepa
5536:Busulfan
5215:Exatecan
5052:Carmofur
4760:assembly
4723: /
4627:23209029
4521:31643478
4490:31643502
4459:31643828
4428:36576980
4353:31644074
4322:31643237
4270:27192092
4213:22957815
4164:41433204
4156:19968576
4113:18221024
4035:22355364
4027:19604118
3612:(rare).
3414:and pro-
3382:Topical:
3319:Topical:
2970:(rare).
2952:Imatinib
2946:(rare).
2772:Axitinib
2716:Afatinib
2553:Melanoma
2446:Melanoma
2278:(rare).
1904:Thiotepa
1619:Lymphoma
1534:Busulfan
831:(rare).
620:(rare),
616:(rare),
562:(rare).
501:(rare).
493:(rare),
387:(rare).
270:(rare).
214:Carmofur
8225:History
8124:grading
8120:Staging
8085:Adenoma
8070:Sarcoma
7324:bcr-abl
6685:myeloid
5171:S phase
5072:Tegafur
4886:S phase
4811:Taxanes
4747:M phase
4647:. WebMD
4618:5892183
4572:. WebMD
4546:. WebMD
4396:. WebMD
4290:. WebMD
4261:7034525
4204:5681218
4078:7507037
3668:vaccine
3260:Topical
2805:Bcr-Abl
793:Bladder
723:Tegafur
595:ovarian
579:Bladder
533:gastric
224:prodrug
196:gastric
44:updated
7956:Cancer
7888:cancer
7884:tumors
6571:VEGF-A
6387:WHO-EM
5996:(Pi3K)
4953:Purine
4756:Block
4625:
4615:
4519:
4488:
4457:
4426:
4351:
4320:
4268:
4258:
4250:
4211:
4201:
4162:
4154:
4146:
4111:
4076:
4068:
4033:
4025:
4017:
3980:
3922:
3892:
3865:
3831:
3646:IM, IV
3531:PO, IV
2567:, and
2226:Glioma
2219:IM, IV
2099:IV, SC
1852:IV, PO
1829:IV, PO
1538:IV, PO
1252:IV, PO
1172:IV, PO
583:breast
525:breast
446:PO, IV
240:SC, IV
188:Breast
132:SC, IV
77:cancer
8208:Misc.
8094:Other
8034:Blood
7565:ANXA2
7537:Other
7435:MAP2K
7306:(ALK)
7291:c-MET
7143:VEGFR
7078:PDGFR
7074:C-kit
6705:Other
6554:EpCAM
5908:IMPDI
5803:Other
4160:S2CID
4050:Drugs
4031:S2CID
3747:Notes
3557:SIADH
3420:IFN-Îł
3377:Oral:
3323:Oral:
3045:VEGFR
3041:PDGFR
3033:c-KIT
2866:PDGFR
2862:EPHA2
2858:c-Kit
2691:Anti-
2648:Anti-
2609:Anti-
2505:Anti-
2411:CTLA4
2337:RANKL
95:Route
8240:Diet
8029:Skin
8024:Bone
7992:oral
7920:Cyst
7890:and
7680:KRAS
7585:IL-2
7567:and
7549:VEGF
7466:EML4
7125:FLT3
7076:and
6964:ErbB
6690:CD33
6672:CD52
6662:CD30
6622:CD20
6490:ErbB
5994:PIKI
5962:HDAC
5411:CCNS
4679:2014
4653:2014
4623:PMID
4578:2014
4552:2014
4517:PMID
4486:PMID
4455:PMID
4424:PMID
4402:2014
4349:PMID
4318:PMID
4296:2014
4266:PMID
4248:ISSN
4236:2016
4209:PMID
4152:PMID
4144:ISSN
4109:PMID
4074:PMID
4066:ISSN
4023:PMID
4015:ISSN
3978:ISBN
3951:2014
3920:ISBN
3890:ISBN
3863:ISBN
3829:ISBN
3718:BRAF
3502:add
3416:IL-2
3412:IL-6
3313:acne
3197:mTOR
3195:2.3
3110:JAK2
3108:and
3106:JAK1
3043:and
3037:FGFR
2990:HER2
2984:HER2
2933:EGFR
2927:EGFR
2904:EGFR
2875:and
2864:and
2841:ARDS
2756:and
2754:VEGF
2732:HER4
2730:and
2728:HER2
2724:EGFR
2693:HER2
2654:I131
2650:CD20
2628:and
2611:CD20
2588:HER2
2507:CD20
2433:IgG4
2385:CD20
2363:CD33
2315:EGFR
2292:VEGF
2263:CD52
2085:and
1861:and
1625:and
1590:and
1560:and
1208:and
1137:and
1105:and
1008:and
950:and
918:and
892:and
851:and
815:and
795:and
758:and
681:and
655:and
605:and
597:and
551:and
543:and
521:Anal
470:and
452:and
296:and
286:and
198:and
165:and
148:and
8132:TNM
7470:ALK
7370:Src
7245:RET
7219:ALK
6669:),
6659:),
6619:),
6604:CD3
6460:L01
6040:ERA
5896:PhI
5867:PrI
5832:CDK
5744:PDT
4742:MIs
4738:SPs
4729:L01
4613:PMC
4605:doi
4256:PMC
4240:doi
4199:PMC
4191:doi
4136:doi
4101:doi
4058:doi
4007:doi
3970:doi
3666:BCG
3499:add
3496:add
3493:add
3408:TNF
2758:PGF
2670:or
2389:90Y
2200:IV
1927:IV
1791:IV
1489:PO
1268:).
940:IV
882:IV
91:INN
8257::
7886:,
7302:,
7272:,
7260:,
7132:,
7071::
6966::
6687::
6615:,
6611:,
6601::
6519:,
6492::
6469:CI
6454:/
6400::
5920:LI
5820:FI
5286:II
5256:II
5078:))
4669:.
4643:.
4621:.
4611:.
4601:19
4599:.
4595:.
4568:.
4542:.
4511:,
4480:,
4449:,
4418:,
4392:.
4366:^
4343:,
4312:,
4286:.
4264:.
4254:.
4246:.
4234:.
4230:.
4207:.
4197:.
4187:54
4185:.
4181:.
4158:.
4150:.
4142:.
4130:.
4107:.
4095:.
4072:.
4064:.
4054:46
4052:.
4029:.
4021:.
4013:.
4003:18
4001:.
3976:.
3904:^
3843:^
3805:^
3714:PO
3691:IV
3672:IB
3622:IV
3597:PO
3569:PO
3555:,
3512:IV
3460:PO
3441:PO
3418:,
3410:,
3403:PO
3353:.
3340:PO
3231:IV
3211:PO
3179:PO
3155:PO
3131:PO
3102:PO
3083:PO
3064:PO
3039:,
3035:,
3028:PO
3005:PO
2980:PO
2956:PO
2923:PO
2900:PO
2860:,
2853:PO
2830:PO
2801:PO
2776:PO
2750:IV
2726:,
2720:PO
2688:IV
2678:.
2666:,
2645:IV
2620:,
2606:IV
2584:IV
2563:,
2559:,
2555:,
2546:IV
2527:IV
2502:IV
2484:,
2480:,
2476:,
2472:,
2468:,
2464:,
2460:,
2456:,
2452:,
2448:,
2429:IV
2407:IV
2381:IV
2359:IV
2333:SC
2311:IV
2288:IV
2259:IV
2183:IV
2164:IV
2141:PO
2122:IV
2089:.
2049:PO
2020:IV
2001:IV
1977:IV
1955:IV
1891:,
1882:PO
1772:PO
1753:IV
1734:IV
1707:IV
1683:,
1679:,
1675:,
1665:IV
1621:,
1612:IV
1586:,
1577:IV
1556:,
1552:,
1517:,
1508:IV
1461:IV
1442:IV
1423:IV
1404:IV
1385:IV
1353:IV
1333:IV
1312:IV
1278:IV
1224:IV
1204:,
1200:,
1191:IV
1153:IV
1133:,
1119:IV
1088:IV
1056:IV
1033:IV
1004:,
1000:,
996:,
992:,
979:PO
946:,
912:IV
888:,
868:,
847:,
841:IV
807:,
799:.
749:PO
727:PO
702:IV
692:.
672:IV
651:,
647:,
638:PO
601:,
593:,
589:,
585:,
581:,
572:IV
547:.
539:,
535:,
531:,
527:,
523:,
466:,
462:,
424:IA
414:.
397:IV
356:,
352:,
348:,
344:,
310:,
306:,
280:IV
252:,
218:PO
194:,
190:,
179:PO
169:.
157:,
144:,
79:.
8182:/
8122:/
7875:e
7868:t
7861:v
7592:)
7588:(
7576:)
7572:(
7556:)
7552:(
7468:-
7382:)
7373:(
7128:(
7120:)
7081:(
7036:)
6972:(
6723:)
6719:(
6697:)
6693:(
6679:)
6675:(
6665:(
6625:(
6607:(
6589:/
6578:)
6574:(
6566:)
6557:(
6538:)
6527:)
6523:(
6515:(
6507:)
6498:(
6462:)
6458:(
6444:e
6437:t
6430:v
6290:)
6281:(
6113:)
6109:/
6105:(
6071:)
6067:(
6059:)
6055:(
6047:)
6043:(
6022:)
5998:(
5989:)
5965:(
5957:)
5935:(
5927:)
5923:(
5915:)
5911:(
5903:)
5899:(
5862:)
5838:(
5827:)
5823:(
5795:)
5776:(
5742:/
5723:)
5704:(
5685:)
5671:(
5648:)
5644:(
5556::
5547:)
5538:(
5533::
5509:)
5505:(
5490::
5471:)
5467:(
5456:)
5447:(
5432::
5413:)
5409:(
5373:)
5359:(
5351:)
5320:)
5316:(
5302:(
5288:+
5277:)
5268:(
5247:)
5193:(
5181:I
5173:)
5169:(
5153:)
5149:(
5128:)
5119:(
5109:)
5105:(
5095:)
5088:(
5074:(
5045:(
5024:)
5015:(
4997:)
4983:(
4978:/
4969:)
4965:(
4944:)
4935:(
4927:)
4908:(
4888:)
4884:(
4855:)
4851:(
4843:)
4814:(
4795:)
4771:(
4749:)
4745:(
4740:/
4731:)
4727:(
4712:e
4705:t
4698:v
4681:.
4655:.
4629:.
4607::
4580:.
4554:.
4404:.
4298:.
4272:.
4242::
4215:.
4193::
4166:.
4138::
4132:6
4115:.
4103::
4097:1
4080:.
4060::
4037:.
4009::
3986:.
3972::
3953:.
3928:.
3898:.
3871:.
3837:.
3373:.
3315:.
3141:.
3047:.
2879:.
2656:.
2571:.
1865:.
1839:.
1095:.
1063:.
1040:.
986:.
819:.
685:.
659:.
609:.
555:.
474:.
56:)
52:(
46:.
20:)
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