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crystal structure of the grb14 bps region in complex with the insulin receptor tyrosine kinase
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210:"Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14"
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Depetris RS, Hu J, Gimpelevich I, Holt LJ, Daly RJ, Hubbard SR (October 2005).
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This article incorporates text from the public domain
176:of the N-terminal portion of the BPS domain to the
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291:. You can help Knowledge (XXG) by
183:groove of the kinase, acting as a
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187:inhibitor. It is composed of two
141:(Between PH and SH2) domain is a
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164:. It mediates inhibition of the
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77:Available protein structures:
226:10.1016/j.molcel.2005.09.001
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137:In molecular biology, the
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191:and a C-terminal helix.
287:-related article is a
145:of approximately 45
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126:structure summary
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170:insulin receptor
151:adaptor proteins
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338:Protein domains
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185:pseudosubstrate
166:tyrosine kinase
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168:domain of the
143:protein domain
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343:Protein stubs
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220:(2): 325–33.
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149:found in the
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293:expanding it
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189:beta strands
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147:amino acids
36:Identifiers
332:Categories
195:References
139:BPS domain
89:structures
264:IPR015042
214:Mol. Cell
178:substrate
67:IPR015042
260:InterPro
244:16246733
106:RCSB PDB
62:InterPro
285:protein
235:4526137
181:peptide
174:binding
55:PF08947
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121:PDBsum
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41:Symbol
283:This
162:Grb14
158:Grb10
289:stub
258:and
256:Pfam
240:PMID
154:Grb7
114:PDBj
110:PDBe
93:ECOD
83:Pfam
50:Pfam
230:PMC
222:doi
172:by
101:PDB
44:BPS
19:BPS
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320:e
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
