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CPK-MB test

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Many cases of CK-MB levels exceeding the blood level of total CK have been reported, especially in newborns with cardiac malformations, especially ventricular septal defects. This reversal of ratios is in favor of pulmonary emboli or vasculitis. An autoimmune reaction creating a complex molecule of
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Boucek RJ Jr; Kasselberg AG; Boerth RC; Parrish MD; Graham TP Jr (July 1982). "Myocardial injury in infants with congenital heart disease: evaluation by creatine kinase MB isoenzyme analysis".
357: 350: 343: 215: 655: 142:. However, recently, there have been improvements to the test that involve measuring the ratio of the CK-MB1 and CK-MB2 isoforms. 185: 123:. It measures the blood level of CK-MB (creatine kinase myocardial band), the bound combination of two variants (isoenzymes 856: 612: 548: 510: 889: 440: 717: 590: 585: 453: 418: 149:
of the B subunit specific to the myocardium whereas the older test detected the presence of cardiac-related
116: 851: 705: 543: 505: 132: 645: 622: 607: 538: 112: 91: 87: 83: 75: 71: 79: 914: 843: 700: 688: 665: 520: 388: 919: 681: 676: 573: 413: 398: 783: 762: 430: 425: 322: 267: 221: 211: 873: 530: 314: 257: 866: 861: 202:
Cabaniss, C. Daniel (1990), Walker, H. Kenneth; Hall, W. Dallas; Hurst, J. Willis (eds.),
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Kinetics of cardiac markers in myocardial infarction with or without reperfusion treatment
285: 774: 630: 403: 393: 262: 245: 108: 908: 817: 796: 710: 635: 568: 318: 139: 335: 822: 791: 694: 595: 383: 39: 600: 580: 515: 477: 468: 463: 458: 375: 120: 246:"Creatine phosphokinase-MB (CPK-MB) and the diagnosis of myocardial infarction" 560: 500: 487: 408: 367: 128: 124: 732: 727: 722: 650: 448: 203: 150: 225: 326: 812: 744: 495: 271: 166: 146: 752: 56: 757: 208:
Clinical Methods: The History, Physical, and Laboratory Examinations
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In some locations, the test has been superseded by the
882: 842: 835: 805: 782: 773: 743: 664: 621: 559: 529: 486: 439: 374: 65: 49: 32: 157:CK and IgG should be taken into consideration. 351: 8: 103:(creatine phosphokinase-MB), also known as 839: 779: 358: 344: 336: 38: 261: 177: 210:(3rd ed.), Boston: Butterworths, 29: 7: 656:Glycogen phosphorylase isoenzyme BB 25: 145:The newer test detects different 186:"CREATINE KINASE – MB CK-MB LQ" 111:used to assist diagnoses of an 1: 613:Comprehensive metabolic panel 319:10.1016/0002-9149(82)90018-2 549:Thyroid-stimulating hormone 511:Total iron-binding capacity 113:acute myocardial infarction 936: 890:Elevated alpha-fetoprotein 244:Guzy PM (December 1977). 37: 61:some places 5 to 25 IU/L 419:BUN-to-creatinine ratio 852:Elevated transaminases 544:Thyroid function tests 506:Transferrin saturation 366:Clinical biochemistry 133:phosphocreatine kinase 646:Lactate dehydrogenase 608:Basic metabolic panel 539:ACTH stimulation test 55:2 to 19.5 U/L (at 37 666:Liver function tests 521:Transferrin receptor 682:Serum total protein 677:Human serum albumin 117:myocardial ischemia 454:Arterial blood gas 902: 901: 898: 897: 831: 830: 784:Blood sugar level 763:Pancreatic lipase 601:Total cholesterol 431:Serum osmolal gap 426:Plasma osmolality 217:978-0-409-90077-4 204:"Creatine Kinase" 97: 96: 16:(Redirected from 927: 874:Hyperproteinemia 840: 780: 360: 353: 346: 337: 331: 330: 302: 296: 295: 293: 292: 282: 276: 275: 265: 241: 235: 234: 233: 232: 199: 193: 192: 190: 182: 131:) of the enzyme 42: 30: 21: 935: 934: 930: 929: 928: 926: 925: 924: 905: 904: 903: 894: 878: 867:Hypoalbuminemia 862:Hypoproteinemia 827: 801: 775:Small molecules 769: 739: 660: 617: 555: 525: 482: 472: 435: 370: 364: 334: 304: 303: 299: 290: 288: 284: 283: 279: 243: 242: 238: 230: 228: 218: 201: 200: 196: 188: 184: 183: 179: 175: 163: 60: 51:Reference range 45: 28: 23: 22: 15: 12: 11: 5: 933: 931: 923: 922: 917: 907: 906: 900: 899: 896: 895: 893: 892: 886: 884: 880: 879: 877: 876: 871: 870: 869: 859: 854: 848: 846: 837: 833: 832: 829: 828: 826: 825: 820: 815: 809: 807: 803: 802: 800: 799: 794: 788: 786: 777: 771: 770: 768: 767: 766: 765: 755: 749: 747: 741: 740: 738: 737: 736: 735: 730: 720: 715: 714: 713: 708: 703: 691: 686: 685: 684: 679: 670: 668: 662: 661: 659: 658: 653: 648: 643: 638: 633: 631:Cardiac marker 627: 625: 623:Cardiovascular 619: 618: 616: 615: 610: 605: 604: 603: 598: 593: 588: 578: 577: 576: 574:Hemoglobin A1c 565: 563: 557: 556: 554: 553: 552: 551: 541: 535: 533: 527: 526: 524: 523: 518: 513: 508: 503: 498: 492: 490: 484: 483: 481: 480: 475: 470: 466: 461: 456: 451: 445: 443: 437: 436: 434: 433: 428: 423: 422: 421: 416: 411: 404:Renal function 401: 396: 391: 386: 380: 378: 372: 371: 365: 363: 362: 355: 348: 340: 333: 332: 297: 277: 236: 216: 194: 176: 174: 171: 170: 169: 162: 159: 109:cardiac marker 95: 94: 69: 63: 62: 53: 47: 46: 43: 35: 34: 27:Cardiac marker 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 932: 921: 918: 916: 913: 912: 910: 891: 888: 887: 885: 881: 875: 872: 868: 865: 864: 863: 860: 858: 855: 853: 850: 849: 847: 845: 841: 838: 834: 824: 821: 819: 818:Hyperuricemia 816: 814: 811: 810: 808: 804: 798: 797:Hyperglycemia 795: 793: 790: 789: 787: 785: 781: 778: 776: 772: 764: 761: 760: 759: 756: 754: 751: 750: 748: 746: 742: 734: 731: 729: 726: 725: 724: 721: 719: 716: 712: 711:AST/ALT ratio 709: 707: 704: 702: 699: 698: 697: 696: 695:transaminases 692: 690: 687: 683: 680: 678: 675: 674: 672: 671: 669: 667: 663: 657: 654: 652: 649: 647: 644: 642: 639: 637: 636:Troponin test 634: 632: 629: 628: 626: 624: 620: 614: 611: 609: 606: 602: 599: 597: 596:Triglycerides 594: 592: 589: 587: 584: 583: 582: 579: 575: 572: 571: 570: 569:Blood glucose 567: 566: 564: 562: 558: 550: 547: 546: 545: 542: 540: 537: 536: 534: 532: 528: 522: 519: 517: 514: 512: 509: 507: 504: 502: 499: 497: 494: 493: 491: 489: 485: 479: 476: 474: 467: 465: 462: 460: 457: 455: 452: 450: 447: 446: 444: 442: 438: 432: 429: 427: 424: 420: 417: 415: 412: 410: 407: 406: 405: 402: 400: 397: 395: 392: 390: 387: 385: 382: 381: 379: 377: 373: 369: 361: 356: 354: 349: 347: 342: 341: 338: 328: 324: 320: 316: 313:(1): 129–35. 312: 308: 301: 298: 287: 281: 278: 273: 269: 264: 259: 256:(6): 455–60. 255: 251: 247: 240: 237: 227: 223: 219: 213: 209: 205: 198: 195: 187: 181: 178: 172: 168: 165: 164: 160: 158: 154: 152: 148: 143: 141: 140:troponin test 136: 134: 130: 126: 122: 118: 114: 110: 106: 102: 93: 89: 85: 81: 77: 73: 70: 68: 64: 58: 54: 52: 48: 41: 36: 31: 19: 857:Elevated ALP 823:Hypouricemia 792:Hypoglycemia 728:Unconjugated 693: 640: 376:Electrolytes 310: 307:Am J Cardiol 306: 300: 289:. Retrieved 280: 253: 250:West. J. Med 249: 239: 229:, retrieved 207: 197: 180: 155: 144: 137: 104: 100: 98: 59:in adults), 915:Blood tests 806:Nitrogenous 641:CPK-MB test 581:Lipid panel 516:Transferrin 464:Bicarbonate 459:Base excess 368:blood tests 121:myocarditis 101:CPK-MB test 33:CPK-MB test 920:Cardiology 909:Categories 733:Conjugated 561:Metabolism 501:Serum iron 488:Iron tests 409:Creatinine 291:2009-01-10 231:2022-04-18 173:References 105:CK-MB test 723:Bilirubin 673:Proteins 651:Myoglobin 449:Anion gap 441:Acid-base 389:Potassium 151:isoenzyme 836:Proteins 813:Azotemia 745:Pancreas 531:Hormones 496:Ferritin 394:Chloride 226:21250193 167:Troponin 161:See also 153:dimers. 147:isoforms 753:Amylase 478:Lactate 473:content 399:Calcium 327:7090995 263:1237914 107:, is a 92:38482-6 88:32673-6 84:13969-1 76:51506-4 72:49551-5 758:Lipase 384:Sodium 325:  272:339548 270:  260:  224:  214:  80:2154-3 883:Other 189:(PDF) 119:, or 67:LOINC 414:Urea 323:PMID 268:PMID 222:PMID 212:ISBN 127:and 99:The 18:CKMB 844:LFT 718:GGT 706:AST 701:ALT 689:ALP 591:HDL 586:LDL 315:doi 258:PMC 254:127 129:CKB 125:CKM 911:: 469:CO 321:. 311:50 309:. 266:. 252:. 248:. 220:, 206:, 135:. 115:, 90:, 86:, 82:, 78:, 74:, 471:2 359:e 352:t 345:v 329:. 317:: 294:. 274:. 191:. 57:C 20:)

Index

CKMB

Reference range
C
LOINC
49551-5
51506-4
2154-3
13969-1
32673-6
38482-6
cardiac marker
acute myocardial infarction
myocardial ischemia
myocarditis
CKM
CKB
phosphocreatine kinase
troponin test
isoforms
isoenzyme
Troponin
"CREATINE KINASE – MB CK-MB LQ"
"Creatine Kinase"
ISBN
978-0-409-90077-4
PMID
21250193
"Creatine phosphokinase-MB (CPK-MB) and the diagnosis of myocardial infarction"
PMC

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