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Carina Kern

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Kern's most recent work focuses on developing a novel theory of ageing focusing on the role of biological constraint as an explanation of how humans age. She has also published work, that looks beyond the latest programmatic theories of ageing, and which seeks to explain the core molecular pathways
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Pérez-Hernández, C. Angélica; Kern, Carina C.; Butkeviciute, Egle; McCarthy, Elizabeth; Dockrell, Hazel M.; Moreno-Altamirano, María Maximina Bertha; Aguilar-López, Bruno A.; Bhosale, Gauri; Wang, Hongyuan; Gems, David; Duchen, Michael R.; Smith, Steven G.; Sánchez-García, Francisco Javier (2020).
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Kern has been an outspoken critic of what she argues are ideas that are inadequate to guide research towards an understanding of the aging process. These include the concept of cellular senescence, which she argues has been outgrown by recent research progress.
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challenged several decades of orthodoxy on notion of single gene switch-off mechanisms that could extend lifespan. The work was cited in several main stream media outlets in the UK including Sky News, Evening Standard The Times and The Independent
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Carina C. Kern; Shivangi Srivastava; Marina Ezcurra; Nancy Hui; StJohn Townsend; Dominik Maczik; Victoria Tse; Jürg Bähler; David Gems (November 16, 2020). "C. elegans hermaphrodites undergo semelparous reproductive death".
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is a geneticist whose research focuses on the biology and genetics of ageing. She is CEO of LinkGevity Limited. Kern was previously a research fellow at the Department of Genetics, Evolution and Environment in the
203:. Her work concerns the underlying causes of aging, and how they give rise to the diseases of later life. She completed her PhD at the University College London's Division of Biosciences. 422: 351:
Kern, Carina C.; Townsend, Stjohn; Salzmann, Antoine; Rendell, Nigel B.; Taylor, Graham W.; Comisel, Ruxandra M.; Foukas, Lazaros C.; Bähler, Jürg; Gems, David (2021).
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Kern is president of the London Evolutionary Network. She is Co-Chair of the CleanTech Business Challenge, an initiative co led by University College London and the
437:"Worm mothers 'sacrifice themselves to provide milk for their young' – Researchers suggest the findings could help discover the key to slowing human ageing" 50: 30: 481:"Mitochondrial Signature in Human Monocytes and Resistance to Infection in C. Elegans During Fumarate-Induced Innate Immune Training" 123: 450: 464: 612: 104: 54: 46: 76: 641: 601: 35: 423:"The way worm mothers provide milk for their young 'could reveal key to slowing human ageing', researchers suggest" 83: 39: 200: 230:
Her work has also looked at how innate immune training can prevent infection at the level of whole organisms.
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from the article and its talk page, especially if potentially
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289:The Alliance For Longevity Initiatives Podcast 8: 532:"Biological constraint as a cause of aging" 53:about living persons that is unsourced or 572: 543: 506: 496: 406: 376: 327: 124:Learn how and when to remove this message 248: 304:"Is 'cellular senescence' a misnomer?" 285:"H-Span Podcast EP 8: Dr. Carina Kern" 7: 600:needs additional or more specific 530:Gems, David; Kern, Carina (2022). 14: 589: 574:10.20944/preprints202310.1387.v1 545:10.20944/preprints202205.0212.v1 140: 20: 302:Gems, D.; Kern, C. C. (2022). 1: 31:biography of a living person 58:must be removed immediately 663: 369:10.1038/s41467-021-25821-y 320:10.1007/s11357-022-00652-x 191:Dr Kern at Linnean Society 149:This biographical article 408:10.1101/2020.11.16.384255 239:at the heart of disease. 201:University College London 498:10.3389/fimmu.2020.01715 485:Frontiers in Immunology 208:London Business School 192: 45:Please help by adding 559:Kern, Carina (2023). 357:Nature Communications 190: 162:by revising it to be 271:"CLEANTEH Committee" 51:Contentious material 642:British scientists 193: 630: 629: 613:adding categories 185: 184: 134: 133: 126: 108: 34:needs additional 654: 625: 622: 616: 593: 585: 579: 578: 576: 556: 550: 549: 547: 527: 521: 520: 510: 500: 475: 469: 468: 461: 455: 454: 447: 441: 440: 433: 427: 426: 419: 413: 412: 410: 397: 391: 390: 380: 348: 342: 341: 331: 314:(5): 2461–2469. 299: 293: 292: 281: 275: 274: 267: 261: 260: 257:"LERN Committee" 253: 180: 177: 171: 144: 143: 136: 129: 122: 118: 115: 109: 107: 66: 47:reliable sources 24: 23: 16: 662: 661: 657: 656: 655: 653: 652: 651: 632: 631: 626: 620: 617: 606: 594: 583: 582: 558: 557: 553: 529: 528: 524: 477: 476: 472: 463: 462: 458: 449: 448: 444: 435: 434: 430: 421: 420: 416: 399: 398: 394: 350: 349: 345: 301: 300: 296: 283: 282: 278: 269: 268: 264: 255: 254: 250: 245: 236: 234:Recent research 216: 181: 175: 172: 160:help improve it 157: 145: 141: 130: 119: 113: 110: 67: 65: 44: 25: 21: 12: 11: 5: 660: 658: 650: 649: 644: 634: 633: 628: 627: 597: 595: 588: 581: 580: 551: 522: 470: 456: 442: 428: 414: 392: 343: 294: 276: 262: 247: 246: 244: 241: 235: 232: 215: 212: 183: 182: 148: 146: 139: 132: 131: 55:poorly sourced 28: 26: 19: 13: 10: 9: 6: 4: 3: 2: 659: 648: 647:Living people 645: 643: 640: 639: 637: 624: 621:November 2023 614: 610: 604: 603: 598:This article 596: 592: 587: 586: 575: 570: 566: 562: 555: 552: 546: 541: 537: 533: 526: 523: 518: 514: 509: 504: 499: 494: 490: 486: 482: 474: 471: 466: 460: 457: 452: 446: 443: 438: 432: 429: 424: 418: 415: 409: 404: 396: 393: 388: 384: 379: 374: 370: 366: 362: 358: 354: 347: 344: 339: 335: 330: 325: 321: 317: 313: 309: 305: 298: 295: 290: 286: 280: 277: 272: 266: 263: 258: 252: 249: 242: 240: 233: 231: 228: 225: 220: 213: 211: 209: 204: 202: 197: 189: 179: 169: 165: 161: 155: 154: 153:like a rĂ©sumĂ© 147: 138: 137: 128: 125: 117: 106: 103: 99: 96: 92: 89: 85: 82: 78: 75: â€“  74: 73:"Carina Kern" 70: 69:Find sources: 63: 59: 56: 52: 48: 42: 41: 37: 32: 27: 18: 17: 618: 599: 564: 554: 535: 525: 488: 484: 473: 459: 445: 431: 417: 395: 360: 356: 346: 311: 307: 297: 288: 279: 265: 251: 237: 229: 222:Her work on 221: 217: 205: 195: 194: 173: 168:encyclopedic 150: 120: 111: 101: 94: 87: 80: 68: 57: 40:verification 33: 363:(1): 5801. 308:GeroScience 196:Carina Kern 151:is written 636:Categories 602:categories 243:References 224:C. elegans 84:newspapers 565:Preprints 536:Preprints 176:June 2024 114:June 2024 36:citations 609:help out 517:32849605 491:: 1715. 387:34611154 338:36068483 62:libelous 607:Please 508:7419614 403:bioRxiv 378:8492707 329:9768054 164:neutral 158:Please 98:scholar 515:  505:  405:  385:  375:  336:  326:  214:Career 100:  93:  86:  79:  71:  105:JSTOR 91:books 29:This 513:PMID 383:PMID 334:PMID 166:and 77:news 38:for 611:by 569:doi 540:doi 503:PMC 493:doi 373:PMC 365:doi 324:PMC 316:doi 638:: 567:. 563:. 538:. 534:. 511:. 501:. 489:11 487:. 483:. 381:. 371:. 361:12 359:. 355:. 332:. 322:. 312:44 310:. 306:. 287:. 210:. 49:. 623:) 619:( 605:. 577:. 571:: 548:. 542:: 519:. 495:: 467:. 453:. 439:. 425:. 411:. 389:. 367:: 340:. 318:: 291:. 273:. 259:. 178:) 174:( 170:. 156:. 127:) 121:( 116:) 112:( 102:· 95:· 88:· 81:· 64:. 43:.

Index

biography of a living person
citations
verification
reliable sources
Contentious material
poorly sourced
libelous
"Carina Kern"
news
newspapers
books
scholar
JSTOR
Learn how and when to remove this message
like a résumé
help improve it
neutral
encyclopedic

University College London
London Business School
C. elegans
"LERN Committee"
"CLEANTEH Committee"
"H-Span Podcast EP 8: Dr. Carina Kern"
"Is 'cellular senescence' a misnomer?"
doi
10.1007/s11357-022-00652-x
PMC
9768054

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