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has to be carefully regulated to control the size of the overlap region, the alignment of those overlaps and the overall length and symmetry of the structure. Without this regulation, signaling faults in cytokinesis can occur, resulting in unequal
90:
Douglas, Max E.; Mishima, Masanori. "Still entangled: Assembly of the central spindle by multiple microtubule modulators".
36:, overlap, and become arranged into antiparallel bundles by various microtubule associated proteins (MAPs) and
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is a microtubule based structure, which forms in between segregating
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119:"The 3Ms of central spindle assembly: microtubules, motors and MAPs"
56:. For these important roles to be achieved successfully the
44:is widely regarded as a key regulating center for
168:"Cytokinesis microtubule organisers at a glance"
166:Lee, KY; Davies, T; Mishima, M (Aug 1, 2012).
8:
92:Seminars in Cell & Developmental Biology
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142:
32:, emanating from opposite halves of the
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123:Nature Reviews Molecular Cell Biology
48:, recruiting proteins for successful
7:
14:
69:, greatly increasing the risk of
1:
104:10.1016/j.semcdb.2010.08.005
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52:positioning and membrane
172:Journal of Cell Science
28:where the two sets of
178:(Pt 15): 3495–500.
184:10.1242/jcs.094672
117:Glotzer, Michael.
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135:10.1038/nrm2609
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67:polyploid cells
65:segregation or
58:central spindle
50:cleavage furrow
42:central spindle
18:central spindle
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5:
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98:(9): 899–908.
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38:motor proteins
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222:Cell anatomy
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30:microtubules
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129:(1): 9–20.
46:cytokinesis
22:chromosomes
77:References
63:chromosome
54:abscission
216:Category
202:22991411
153:19197328
26:anaphase
193:3445320
144:2789570
24:during
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71:cancer
40:. The
198:PMID
149:PMID
34:cell
16:The
188:PMC
180:doi
176:125
139:PMC
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