42:
694:
445:
312:
in 1990, and Gapped BLAST and PSI-BLAST in 1997. BLAST eventually became the most widely-used and highly-cited (over 160,000 citations as of 2021) sequence alignment program in the field, and the NCBI BLAST server today is one of its most heavily used resources.
2182:
1439:
276:
at the U.S. National
Institutes of Health. Under his leadership, NCBI grew from fewer than a dozen people to more than 500 scientific staff, and it now hosts hundreds of scientific and medical databases including
2187:
2202:
329:
258:
150:
69:
2197:
1435:
490:
409:
387:
269:
210:
142:
343:
567:
229:, one of the most heavily used sites in the world for the search and retrieval of biomedical information. Lipman is one of the original authors of the
2192:
304:
Lipman is very well known for his seminal work on a series of sequence similarity algorithms, starting from the Wilbur-Lipman algorithm in 1983,
508:
1422:
289:, dbGaP, dbSNP, the Sequence Read Archive (SRA), RefSeq, PubChem, and many more. The internal research program at NCBI included groups led by
1344:
2167:
336:
1400:
2172:
549:
1673:
332:(INSDC), a fully open, unrestricted database of genome sequences that has been the world's repository of such data since 1990.
430:
1724:
1271:
706:
214:
1246:
1393:
996:
416:
394:
273:
95:
1984:
1897:
401:
321:
90:
2146:
1369:
2121:
2040:
1907:
730:
316:
Lipman also worked for many years with Dennis A. Benson and others at NCBI on the maintenance and improvement of
2096:
1415:
1295:
1959:
1841:
1514:
1099:
Benson, D. A.; Cavanaugh, M.; Clark, K.; Karsch-Mizrachi, I.; Lipman, D. J.; Ostell, J.; Sayers, E. W. (2012).
482:
41:
460:
575:
2060:
2141:
2177:
1902:
1576:
325:
2131:
1408:
1309:
309:
230:
120:
80:
2050:
2030:
1826:
1709:
925:
874:
819:
772:
512:
298:
128:
1310:"ISCB Names 2004 Senior Scientist Accomplishment Award Winner, Dr. David Lipman ISCB Newsletter 7-3"
2080:
2045:
2035:
2009:
1704:
320:, one of the world's largest databases of genome and protein sequence data. GenBank along with the
132:
2075:
1805:
1370:"Dr. David Lipman Receives White House "Open Science" Champions of Change Award on Behalf of NCBI"
1999:
1979:
1974:
1938:
1933:
1714:
1021:
534:
362:
339:, a project to sequence and make available the genomes of thousands of influenza virus isolates.
254:
1148:
Benson, D. A.; Karsch-Mizrachi, I.; Clark, K.; Lipman, D. J.; Ostell, J.; Sayers, E. W. (2011).
1994:
1954:
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1750:
1601:
1555:
1540:
1334:
1228:
1179:
1130:
1081:
1013:
953:
890:
847:
788:
628:
124:
2111:
2070:
1872:
1851:
1775:
1586:
1524:
1483:
1218:
1210:
1169:
1161:
1120:
1112:
1071:
1063:
1039:
1005:
971:
943:
933:
882:
837:
827:
780:
618:
610:
529:
375:
290:
250:
238:
160:
146:
65:
2106:
1964:
1795:
1790:
1745:
1719:
1642:
1627:
1622:
1504:
1473:
673:
350:
1550:
693:
929:
878:
823:
776:
450:
1882:
1800:
1760:
1678:
1596:
1478:
1453:
1339:
1223:
1198:
1174:
1149:
1125:
1100:
623:
598:
367:
286:
234:
116:
1076:
1051:
1009:
948:
913:
842:
807:
597:
Benson, D. A.; Karsch-Mizrachi, I.; Lipman, D. J.; Ostell, J.; Wheeler, D. L. (2007).
553:
2161:
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2065:
1928:
1892:
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1785:
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1729:
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1571:
1545:
1468:
1197:
Benson, D. A.; Karsch-Mizrachi, I.; Lipman, D. J.; Ostell, J.; Sayers, E. W. (2010).
983:
294:
179:
1272:"National Library of Medicine Announces Departure of NCBI Director Dr. David Lipman"
1025:
707:"National Library of Medicine Announces Departure of NCBI Director Dr. David Lipman"
646:
2136:
2004:
1989:
1969:
1923:
1856:
1846:
1836:
1821:
1755:
1668:
1658:
1617:
1581:
1509:
1458:
865:
Lipman, D.; Pearson, W. (1985). "Rapid and sensitive protein similarity searches".
669:
374:
In May 2017, Lipman left his role at the NCBI to join the plant-based meat company
164:
1052:"Gapped BLAST and PSI-BLAST: A new generation of protein database search programs"
784:
2116:
1887:
1765:
1663:
1519:
1499:
1463:
1431:
1043:
979:
975:
423:
405:
358:
354:
99:
918:
Proceedings of the
National Academy of Sciences of the United States of America
812:
Proceedings of the
National Academy of Sciences of the United States of America
2025:
1780:
1591:
1250:
550:"David J. Lipman, MD, Director, National Center for Biotechnology Information"
1067:
2101:
886:
206:
17:
1232:
1183:
1134:
938:
632:
1214:
1165:
1116:
1085:
1017:
957:
894:
851:
832:
792:
390:
Award for outstanding contributions to
Biomolecular Technologies in 1996.
614:
2055:
317:
278:
218:
738:
282:
226:
760:
494:
808:"Rapid similarity searches of nucleic acid and protein data banks"
305:
222:
1355:
991:
688:
1404:
684:
2183:
509:"Sense from Sequences: Stephen F. Altschul on Bettering BLAST"
237:. In 2017, he left NCBI and became Chief Science Officer at
2188:
Members of the United States
National Academy of Sciences
1042:; Madden, T. L.; Schäffer, A. A.; Zhang, J.; Zhang, Z.;
330:
International
Nucleotide Sequence Database Collaboration
568:"Open Access Now | Conversation with David Lipman"
259:
University at
Buffalo, The State University of New York
151:
University at
Buffalo, The State University of New York
70:
University at
Buffalo, The State University of New York
233:
sequence alignment program, and a respected figure in
759:
Tatusov, R. L.; Koonin, E. V.; Lipman, D. J. (1997).
2089:
2018:
1947:
1916:
1865:
1814:
1738:
1687:
1651:
1610:
1564:
1533:
1492:
1446:
914:"Improved tools for biological sequence comparison"
524:
522:
174:
156:
138:
112:
86:
75:
61:
51:
32:
530:"Research Institute Posts Gene Data on Internet"
2203:University at Buffalo School of Medicine alumni
1436:International Society for Computational Biology
491:International Society for Computational Biology
410:International Society for Computational Biology
388:Association of Biomolecular Resource Facilities
342:He was one of the original signatories of the
249:Lipman received his undergraduate degree from
209:who from 1989 to 2017 was the director of the
1416:
270:National Center for Biotechnology Information
211:National Center for Biotechnology Information
143:National Center for Biotechnology Information
8:
344:Bethesda Statement on Open Access Publishing
2198:Members of the National Academy of Medicine
761:"A Genomic Perspective on Protein Families"
293:(another BLAST co-author), David Landsman,
1423:
1409:
1401:
1296:"Institute of Medicine Elects New Members"
692:
415:In 2005, Dr. Lipman was elected to the US
223:International Sequence Database Consortium
40:
29:
1222:
1173:
1124:
1075:
947:
937:
841:
831:
622:
476:
474:
268:Lipman was the founding director of the
1247:"Biology Direct | Editorial board"
470:
1335:"Open Science | the White House"
806:Wilbur, W. J.; Lipman, D. J. (1983).
335:He was one of the originators of the
7:
422:In 2013, he received the award of a
1394:Warren Alpert Foundation Prize 2023
992:"Basic local alignment search tool"
426:"Open Science" Champion of Change.
337:Influenza Genome Sequencing Project
25:
731:"David J. Lipman, M.D. Biography"
2193:21st-century American biologists
443:
1347:from the original on 2017-01-21
647:"david lipman – Google Scholar"
393:In 2000, he was elected to the
431:Warren Alpert Foundation Prize
1:
1010:10.1016/S0022-2836(05)80360-2
378:as chief scientific officer.
215:National Institutes of Health
997:Journal of Molecular Biology
785:10.1126/science.278.5338.631
429:In 2023, he was awarded the
417:National Academy of Sciences
400:In 2004, he was awarded the
395:National Academy of Medicine
274:National Library of Medicine
96:National Academy of Sciences
79:Influence on development of
1209:(Database issue): D32–D37.
1160:(Database issue): D48–D53.
1111:(Database issue): D36–D42.
609:(Database issue): D25–D30.
402:ISCB Senior Scientist Award
322:European Nucleotide Archive
125:Sequence comparison methods
91:ISCB Senior Scientist Award
2219:
2168:American bioinformaticians
170:
105:
46:David Lipman in June 2013
39:
672:publications indexed by
2173:Brown University alumni
887:10.1126/science.2983426
221:, the U.S. node of the
1203:Nucleic Acids Research
1154:Nucleic Acids Research
1105:Nucleic Acids Research
1068:10.1093/nar/25.17.3389
1056:Nucleic Acids Research
939:10.1073/pnas.85.8.2444
603:Nucleic Acids Research
511:. 2000. Archived from
326:DNA Data Bank of Japan
297:(a prolific author on
217:. NCBI is the home of
833:10.1073/pnas.80.3.726
121:Computational biology
81:BLAST (biotechnology)
691:Bibliography Server
386:Lipman received the
299:comparative genomics
129:Comparative genomics
2081:Gustavo Stolovitzky
1705:Julio Collado-Vides
1215:10.1093/nar/gkq1079
1166:10.1093/nar/gkr1202
1117:10.1093/nar/gks1195
930:1988PNAS...85.2444P
879:1985Sci...227.1435L
873:(4693): 1435–1441.
824:1983PNAS...80..726W
777:1997Sci...278..631T
301:), and L. Aravind.
133:Molecular evolution
94:Member of the U.S.
2147:Reinhard Schneider
1939:Marie-France Sagot
1934:Xiaole Shirley Liu
674:Microsoft Academic
651:Scholar.google.com
615:10.1093/nar/gkm929
535:The New York Times
363:scientific journal
27:American biologist
2155:
2154:
2061:Núria López Bigas
1995:Katherine Pollard
1955:Serafim Batzoglou
1878:Terry Gaasterland
1602:Gunnar von Heijne
1541:Michael Ashburner
1356:National Archives
1062:(17): 3389–3402.
972:Altschul, Stephen
771:(5338): 631–637.
572:Biomedcentral.com
382:Awards and honors
257:in 1980 from the
200:
199:
107:Scientific career
16:(Redirected from
2210:
2112:Takashi Gojobori
2071:Teresa Przytycka
2051:Christina Leslie
1873:Patricia Babbitt
1852:Olga Troyanskaya
1776:Christine Orengo
1674:Robert Gentleman
1525:Alfonso Valencia
1484:Michael Waterman
1440:year of election
1425:
1418:
1411:
1402:
1396:
1391:
1385:
1384:
1382:
1380:
1374:Ncbi.nlm.nih.gov
1366:
1360:
1359:
1353:
1352:
1331:
1325:
1324:
1322:
1320:
1306:
1300:
1299:
1292:
1286:
1285:
1283:
1282:
1268:
1262:
1261:
1259:
1258:
1249:. Archived from
1243:
1237:
1236:
1226:
1194:
1188:
1187:
1177:
1145:
1139:
1138:
1128:
1096:
1090:
1089:
1079:
1036:
1030:
1029:
968:
962:
961:
951:
941:
924:(8): 2444–2448.
908:Pearson, W. R.;
905:
899:
898:
862:
856:
855:
845:
835:
803:
797:
796:
756:
750:
749:
747:
746:
737:. Archived from
727:
721:
720:
718:
717:
703:
697:
696:
682:
676:
667:
661:
660:
658:
657:
643:
637:
636:
626:
594:
588:
587:
585:
583:
574:. Archived from
564:
558:
557:
552:. Archived from
546:
540:
539:
538:. June 26, 1997.
526:
517:
516:
505:
499:
498:
493:. Archived from
478:
447:
446:
376:Impossible Foods
308:search in 1985,
291:Stephen Altschul
251:Brown University
239:Impossible Foods
196:
193:
191:
189:
187:
185:
183:
181:
161:Stephen Altschul
157:Notable students
147:Brown University
66:Brown University
44:
30:
21:
2218:
2217:
2213:
2212:
2211:
2209:
2208:
2207:
2158:
2157:
2156:
2151:
2107:Mikhail Gelfand
2085:
2031:A. Keith Dunker
2014:
1985:Rafael Irizarry
1965:Mark Borodovsky
1943:
1912:
1898:William Pearson
1861:
1827:Andrea Califano
1810:
1796:Anna Tramontano
1791:Sarah Teichmann
1746:Helen M. Berman
1734:
1720:Thomas Lengauer
1683:
1647:
1643:Steven Salzberg
1628:Minoru Kanehisa
1623:David Eisenberg
1606:
1560:
1529:
1505:Lawrence Hunter
1488:
1442:
1429:
1399:
1392:
1388:
1378:
1376:
1368:
1367:
1363:
1350:
1348:
1333:
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1328:
1318:
1316:
1308:
1307:
1303:
1294:
1293:
1289:
1280:
1278:
1276:www.nlm.nih.gov
1270:
1269:
1265:
1256:
1254:
1245:
1244:
1240:
1196:
1195:
1191:
1147:
1146:
1142:
1098:
1097:
1093:
1038:
1037:
1033:
970:
969:
965:
907:
906:
902:
864:
863:
859:
805:
804:
800:
758:
757:
753:
744:
742:
729:
728:
724:
715:
713:
711:www.nlm.nih.gov
705:
704:
700:
685:David J. Lipman
683:
679:
670:David J. Lipman
668:
664:
655:
653:
645:
644:
640:
596:
595:
591:
581:
579:
578:on 29 June 2011
566:
565:
561:
548:
547:
543:
528:
527:
520:
507:
506:
502:
480:
479:
472:
468:
467:
466:
461:David J. Lipman
448:
444:
439:
408:in 2009 by the
404:and elected an
384:
351:editor-in-chief
349:He is also the
266:
247:
205:is an American
203:David J. Lipman
178:
163:
149:
145:
131:
127:
123:
119:
98:
93:
68:
62:Alma mater
57:
56:David J. Lipman
47:
35:
28:
23:
22:
15:
12:
11:
5:
2216:
2214:
2206:
2205:
2200:
2195:
2190:
2185:
2180:
2175:
2170:
2160:
2159:
2153:
2152:
2150:
2149:
2144:
2139:
2134:
2129:
2124:
2119:
2114:
2109:
2104:
2099:
2097:Barbara Bryant
2093:
2091:
2087:
2086:
2084:
2083:
2078:
2073:
2068:
2063:
2058:
2053:
2048:
2043:
2041:Wolfgang Huber
2038:
2033:
2028:
2022:
2020:
2016:
2015:
2013:
2012:
2007:
2002:
1997:
1992:
1987:
1982:
1977:
1972:
1967:
1962:
1957:
1951:
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1945:
1944:
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1941:
1936:
1931:
1926:
1920:
1918:
1914:
1913:
1911:
1910:
1905:
1900:
1895:
1890:
1885:
1883:Hanah Margalit
1880:
1875:
1869:
1867:
1863:
1862:
1860:
1859:
1854:
1849:
1844:
1839:
1834:
1829:
1824:
1818:
1816:
1812:
1811:
1809:
1808:
1803:
1801:Shoshana Wodak
1798:
1793:
1788:
1783:
1778:
1773:
1768:
1763:
1758:
1753:
1751:Steven Brenner
1748:
1742:
1740:
1736:
1735:
1733:
1732:
1727:
1725:Michael Levitt
1722:
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1712:
1707:
1702:
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1614:
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1608:
1607:
1605:
1604:
1599:
1597:Martin Vingron
1594:
1589:
1584:
1579:
1574:
1568:
1566:
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1559:
1558:
1556:Richard Durbin
1553:
1548:
1543:
1537:
1535:
1531:
1530:
1528:
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1522:
1517:
1512:
1507:
1502:
1496:
1494:
1490:
1489:
1487:
1486:
1481:
1479:Janet Thornton
1476:
1471:
1466:
1461:
1456:
1454:David Haussler
1450:
1448:
1444:
1443:
1430:
1428:
1427:
1420:
1413:
1405:
1398:
1397:
1386:
1361:
1340:whitehouse.gov
1326:
1301:
1287:
1263:
1238:
1189:
1140:
1091:
1031:
1004:(3): 403–410.
963:
900:
857:
818:(3): 726–730.
798:
751:
722:
698:
677:
662:
638:
589:
559:
556:on 2013-09-26.
541:
518:
515:on 2007-10-07.
500:
497:on 2017-03-20.
483:"ISCB Fellows"
469:
449:
442:
441:
440:
438:
435:
383:
380:
368:Biology Direct
287:PubMed Central
272:, part of the
265:
262:
246:
243:
235:bioinformatics
213:(NCBI) at the
198:
197:
176:
172:
171:
168:
167:
158:
154:
153:
140:
136:
135:
117:Bioinformatics
114:
110:
109:
103:
102:
88:
84:
83:
77:
76:Known for
73:
72:
63:
59:
58:
55:
53:
49:
48:
45:
37:
36:
33:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2215:
2204:
2201:
2199:
2196:
2194:
2191:
2189:
2186:
2184:
2181:
2179:
2178:Living people
2176:
2174:
2171:
2169:
2166:
2165:
2163:
2148:
2145:
2143:
2140:
2138:
2135:
2133:
2130:
2128:
2127:Fran Lewitter
2125:
2123:
2120:
2118:
2115:
2113:
2110:
2108:
2105:
2103:
2100:
2098:
2095:
2094:
2092:
2088:
2082:
2079:
2077:
2074:
2072:
2069:
2067:
2064:
2062:
2059:
2057:
2054:
2052:
2049:
2047:
2046:Sorin Istrail
2044:
2042:
2039:
2037:
2036:Eran Halperin
2034:
2032:
2029:
2027:
2024:
2023:
2021:
2017:
2011:
2010:Xuegong Zhang
2008:
2006:
2003:
2001:
1998:
1996:
1993:
1991:
1988:
1986:
1983:
1981:
1978:
1976:
1973:
1971:
1968:
1966:
1963:
1961:
1958:
1956:
1953:
1952:
1950:
1946:
1940:
1937:
1935:
1932:
1930:
1929:Eleazar Eskin
1927:
1925:
1922:
1921:
1919:
1915:
1909:
1906:
1904:
1901:
1899:
1896:
1894:
1893:Bernard Moret
1891:
1889:
1886:
1884:
1881:
1879:
1876:
1874:
1871:
1870:
1868:
1864:
1858:
1855:
1853:
1850:
1848:
1845:
1843:
1842:William Noble
1840:
1838:
1835:
1833:
1832:Daphne Koller
1830:
1828:
1825:
1823:
1820:
1819:
1817:
1813:
1807:
1804:
1802:
1799:
1797:
1794:
1792:
1789:
1787:
1786:Lincoln Stein
1784:
1782:
1779:
1777:
1774:
1772:
1771:Michal Linial
1769:
1767:
1764:
1762:
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1990:Laxmi Parida
1970:Rita Casadio
1960:Judith Blake
1924:Vineet Bafna
1857:Tandy Warnow
1847:Lior Pachter
1837:Anders Krogh
1822:Alex Bateman
1806:Haim Wolfson
1756:Dan Gusfield
1669:Nir Friedman
1659:Amos Bairoch
1618:Pierre Baldi
1582:Jill Mesirov
1551:Søren Brunak
1515:Chris Sander
1510:Eugene Myers
1474:Temple Smith
1459:David Lipman
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165:Mark Boguski
139:Institutions
106:
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18:David Lipman
2122:David Jones
2117:Trey Ideker
2000:Ben Raphael
1980:Osamu Gotoh
1975:Paul Flicek
1888:Yves Moreau
1766:Janet Kelso
1761:Barry Honig
1715:Des Higgins
1679:Andrej Šali
1664:Ewan Birney
1546:Phil Bourne
1520:Gary Stormo
1500:Russ Altman
1464:Webb Miller
424:White House
406:ISCB Fellow
355:open-access
100:ISCB Fellow
2162:Categories
2066:Dana Pe'er
2026:Atul Butte
1908:Mike Steel
1903:Mona Singh
1781:Aviv Regev
1592:Ron Shamir
1577:Peter Karp
1351:2016-04-02
1281:2017-05-04
1257:2011-10-28
1044:Miller, W.
745:2017-02-09
716:2017-05-05
656:2017-03-26
437:References
2142:Mihai Pop
2102:Sean Eddy
1199:"GenBank"
1150:"GenBank"
1101:"GenBank"
599:"GenBank"
328:form the
245:Education
207:biologist
190:/research
1345:Archived
1314:Iscb.org
1233:21071399
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1135:23193287
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192:/staff
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310:BLAST
306:FASTA
231:BLAST
182:.ncbi
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188:.gov
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