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Although Mason began his research career as a physicist studying controlled thermonuclear fusion, he is best known for his work on cellular immunology, summarised in outline here. Mason's most important contributions to immunology were his studies defining the existence, cell surface phenotype and
620:"Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC- cells and CD4(+)CD8(-) thymocytes"
450:
Saoudi A, Seddon B, Heath V, Fowell D, Mason D (1996). "The physiological role of regulatory T cells in the prevention of autoimmunity: the function of the thymus in the generation of the regulatory T cell subset".
571:"Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential"
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174:. These were among the earliest demonstrations of the requirement for Treg in restraining the pathogenic activity of CD4+ T cells and prevention of
162:: CD45RC in rats and CD45RB in mice) and their capacity to prevent the pathogenic activity of the OX22hi subset. While he carried out studies into
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Sakaguchi S (2004). "Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses".
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154:. Mason's research identified the immuno-regulatory capacity of a population of CD4+ T cells that express low levels of OX22 (an
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669:"The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients"
194:. This contains his reflections on the scope and limitations of science, and his contemplations of "The Broader View".
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496:"OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset"
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in the prevention of diabetes and thyroiditis and highlighted the role for the thymus in the development of
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117:(1934 – 13 January 2021) was a British immunologist and professor of immunology in the
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Gibson, A.; Mason, D.W. (1969). "Binary
Collision Losses in Stellarators".
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166:, the work for which he is most recognised focused mainly on the role of
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379:"Leading Immunologist and Dunn School Alumnus Don Mason - Obituary"
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Science, Mystical
Experience and Religious Belief: A Personal View
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Science, Mystical
Experience and Religious Belief: A Personal View
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Gibson, A.; Mason, D.W. (1962). "Energy Loss
Processes in ZETA".
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The
Balance Within: The Science Connecting Health and Emotions
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and a Quaker. He became a vegan in 1977. In 2006, he authored
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250:"Honorary members | British Society for Immunology"
393:"Behind the picture: Don Mason and his T cell legacy"
755:. York, England: The Ebor Press - William Sessions.
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753:Science, Mystical Experience and Religious Belief
129:. Professor Mason is best known for his work on
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16:British immunologist and professor (1934–2021)
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197:Mason died aged 86 on 13 January 2021.
178:. Mason retired from research in 1999.
19:For other people named Don Mason, see
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667:Saoudi A, Seddon B, Mason D (1996).
123:Sir William Dunn School of Pathology
99:Sir William Dunn School of Pathology
95:Atomic Energy Research Establishment
265:Proceedings of the Physical Society
841:Writers about religion and science
465:10.1111/j.1600-065x.1996.tb00905.x
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673:Journal of Experimental Medicine
624:Journal of Experimental Medicine
575:Journal of Experimental Medicine
549:, USA: Times Books, p. 97,
500:Journal of Experimental Medicine
230:. British Society for Immunology
121:Cellular Immunology Unit at the
228:"New Honorary Members for BSI"
139:British Society for Immunology
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133:and their role in preventing
543:Esther M. Sternberg (2001),
718:Annual Review of Immunology
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618:Seddon B, Mason D (1999).
569:Fowell D, Mason D (1993).
494:Powrie F, Mason D (1990).
352:10.1038/s41590-021-00884-7
320:10.1088/0032-1028/11/2/004
285:10.1088/0370-1328/79/2/312
21:Don Mason (disambiguation)
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397:Medical Research Council
335:"Don Mason (1934-2021)"
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826:British immunologists
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587:10.1084/jem.177.3.627
453:Immunological Reviews
201:Selected publications
789:University of Oxford
751:Mason, D.W. (2006).
423:"Don Mason Obituary"
127:University of Oxford
103:University of Oxford
312:1969PlPh...11..121G
277:1962PPS....79..326G
778:"The Broader View"
164:multiple sclerosis
152:regulatory T cells
131:regulatory T cells
78:Regulatory T Cells
556:978-0-7167-4445-0
339:Nature Immunology
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792:. Retrieved
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150:function of
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145:Notable work
135:autoimmunity
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91:Institutions
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58:(2021-01-13)
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821:2021 deaths
816:1934 births
459:: 195–216.
65:Citizenship
810:Categories
724:: 531–62.
345:(4): 395.
234:21 January
214:References
32:Don Mason
738:15032588
481:40160832
432:15 March
402:15 March
358:15 March
76:Work on
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209:(2006)
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188:vegan
172:Tregs
168:Tregs
796:2016
757:ISBN
734:PMID
699:PMID
650:PMID
601:PMID
551:ISBN
526:PMID
469:PMID
434:2021
404:2021
360:2021
236:2021
160:CD45
53:Died
45:1934
41:1934
38:Born
726:doi
689:PMC
681:doi
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