Knowledge (XXG)

Fumonisin

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At least 15 different fumonisins have so far been reported and other minor metabolites have been identified, although most of them have not been shown to occur naturally. In 2015, a unique class of non-aminated fumonisins was reported on grapes infected with
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Gelderblom, Wentzel C. A.; Marasas, Walter F. O.; Vleggaar, R.; Thiel, Pieter G.; Cawood, M. E. (February 1992). "Fumonisins: Isolation, chemical characterization and biological effects".
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Renaud, J.B.R; M.J Kelman; Tianyu F. Qi; K.A. Seifert; M.W. Sumarah (2015). "Product ion filtering with rapid polarity switching for the detection of all fumonisins and AAL-toxins".
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As the fumonisins appear to be non-genotoxic the possibility that they belong to another class of non-genotoxic carcinogens, the peroxisome proliferators, was investigated
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Genetic engineering is reported as a promising means of detoxifying mycotoxins. This approach may provide innovative solutions to the problem of fumonisin in corn.
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Mycotoxicology: Introduction to the Mycology, Plant Pathology, Chemistry, Toxicology, and Pathology of Naturally Occurring Mycotoxicoses In Animals and Man
1348: 558: 234:"Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene" 687: 679: 390: 365: 298: 216: 683: 571: 423: 657: 786: 1476: 1433: 938: 582: 577: 697: 322:(22). Rapid Communications in Mass Spectrometry Volume 29, Issue 22, 30 November 2015, Pages 2131–2139: 2131–2139. 987: 151: 232:
Igawa, T; Takahashi-Ando, N; Ochiai, N; Ohsato, S; Shimizu, T; Kudo, T; Yamaguchi, I; Kimura, M (March 2007).
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note: some toxins are produced by lower species and pass through intermediate species
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USAMRIID's Medical Management of Biological Casualties Handbook, 6th Ed
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Jackson, Lauren S.; Jonathan W. DeVries; Lloyd B. Bullerman (1996).
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Marasas, W.F.O.; J.D. Miller; R.T. Riley; A. Visconti (2000).
103:, although their toxicities have not yet been established. 293:. Vammala, Finland: World Health Organization. p. 9. 56:
section. They have strong structural similarity to
1675: 1582: 1556: 1545: 1500: 1442: 1336: 1325: 1094: 951: 922: 858: 795: 742: 715: 668: 634: 607: 520: 511: 500: 491: 480: 291:Environmental Health Criteria 219: Fumonisin B1 417: 8: 211:. New York, NY: Plenum Press. p. 289. 1553: 1333: 640: 517: 508: 497: 488: 424: 410: 402: 1349:Androctonus australis hector insect toxin 316:Rapid Communications in Mass Spectrometry 265: 150:at the U.S. National Library of Medicine 381:Marasas, W.F.O.; Paul E. Nelson (1987). 140: 7: 132:, is also referred to as F-2 toxin. 67:More specifically, it can refer to: 703:Staphylococcal Enterotoxin B (SEB) 34:Chemical structure of fumonisin B1 25: 1755: 1754: 787:Extracellular adenylate cyclase 1: 939:Fibronectin binding protein A 60:, the backbone precursor of 680:Staphylococcus aureus alpha 658:Panton–Valentine leukocidin 128:The estrogenic metabolite, 27:Group of chemical compounds 1797: 698:Toxic shock syndrome toxin 1750: 1737: 1595:(+)-Allopumiliotoxin 267A 643: 988:beta-Nitropropionic acid 152:Medical Subject Headings 101:Aspergillus welwitschiae 772:Heat-labile enterotoxin 763:heat-stable enterotoxin 125:, a common grain mold. 881:Bacillus thuringiensis 238:Appl Environ Microbiol 35: 33: 782:Pseudomonas exotoxin 258:10.1128/aem.01077-06 328:2015RCMS...29.2131R 250:2007ApEnM..73.1622I 1698:Alpha-Bungarotoxin 868:Lipopolysaccharide 826:Pore-forming toxin 209:Fumonisins In Food 178:10.1007/BF00497273 36: 1768: 1767: 1733: 1732: 1703:Beta-Bungarotoxin 1647:Pumiliotoxin 251D 1541: 1540: 947: 946: 934:Clumping factor A 854: 853: 738: 737: 711: 710: 630: 629: 16:(Redirected from 1788: 1758: 1757: 1686: 1642:Histrionicotoxin 1588: 1562: 1554: 1506: 1460:Alpha-latrotoxin 1448: 1342: 1334: 1066:Sterigmatocystin 1018:, Fumonisin B3, 982:epsilon-amanitin 901:B. thuringiensis 730:Diphtheria toxin 673: 641: 610: 526: 518: 509: 498: 489: 426: 419: 412: 403: 397: 396: 378: 372: 371: 354: 348: 347: 336:10.1002/rcm.7374 311: 305: 304: 286: 280: 279: 269: 229: 223: 222: 204: 198: 197: 161: 155: 145: 21: 1796: 1795: 1791: 1790: 1789: 1787: 1786: 1785: 1771: 1770: 1769: 1764: 1746: 1729: 1725:Cardiotoxin III 1681: 1676: 1671: 1583: 1578: 1557: 1549: 1537: 1501: 1496: 1443: 1438: 1337: 1329: 1321: 1225:Resiniferatoxin 1090: 943: 925: 918: 883:delta endotoxin 850: 791: 777:Pertussis toxin 745: 734: 707: 669: 664: 626: 622:Listeriolysin O 608: 603: 521: 503: 483: 476: 430: 400: 393: 380: 379: 375: 368: 356: 355: 351: 313: 312: 308: 301: 288: 287: 283: 231: 230: 226: 219: 206: 205: 201: 163: 162: 158: 146: 142: 138: 113: 42:are a group of 28: 23: 22: 15: 12: 11: 5: 1794: 1792: 1784: 1783: 1773: 1772: 1766: 1765: 1763: 1762: 1751: 1748: 1747: 1745: 1744: 1738: 1735: 1734: 1731: 1730: 1728: 1727: 1722: 1717: 1712: 1707: 1706: 1705: 1700: 1689: 1687: 1673: 1672: 1670: 1669: 1667:Zetekitoxin AB 1664: 1659: 1654: 1649: 1644: 1639: 1634: 1633: 1632: 1627: 1622: 1617: 1612: 1602: 1597: 1591: 1589: 1580: 1579: 1577: 1576: 1571: 1565: 1563: 1551: 1543: 1542: 1539: 1538: 1536: 1535: 1530: 1525: 1520: 1515: 1509: 1507: 1498: 1497: 1495: 1494: 1489: 1484: 1479: 1474: 1469: 1464: 1463: 1462: 1451: 1449: 1440: 1439: 1437: 1436: 1431: 1426: 1421: 1416: 1411: 1406: 1401: 1396: 1391: 1386: 1381: 1376: 1371: 1366: 1361: 1356: 1351: 1345: 1343: 1331: 1323: 1322: 1320: 1319: 1314: 1313: 1312: 1307: 1297: 1292: 1287: 1282: 1277: 1272: 1267: 1262: 1257: 1252: 1247: 1242: 1237: 1232: 1227: 1222: 1217: 1215:Pseudaconitine 1212: 1207: 1202: 1197: 1192: 1187: 1182: 1177: 1172: 1167: 1162: 1157: 1155:Djenkolic acid 1152: 1147: 1142: 1137: 1132: 1127: 1122: 1117: 1112: 1107: 1101: 1099: 1092: 1091: 1089: 1088: 1083: 1078: 1073: 1068: 1063: 1058: 1053: 1048: 1043: 1038: 1033: 1028: 1023: 1005: 1000: 995: 990: 985: 978:gamma-amanitin 970:alpha-amanitin 963: 957: 955: 949: 948: 945: 944: 942: 941: 936: 930: 928: 920: 919: 917: 916: 915: 914: 909: 897: 896: 895: 890: 877: 876: 875: 864: 862: 856: 855: 852: 851: 849: 848: 847: 846: 830: 829: 828: 816: 815: 814: 801: 799: 793: 792: 790: 789: 784: 779: 774: 765: 757: 750: 748: 740: 739: 736: 735: 733: 732: 727: 721: 719: 717:Actinomycetota 713: 712: 709: 708: 706: 705: 700: 695: 690: 676: 674: 671:Staphylococcus 666: 665: 663: 662: 661: 660: 650: 644: 638: 632: 631: 628: 627: 625: 624: 619: 613: 611: 605: 604: 602: 601: 600: 599: 587: 586: 585: 580: 568: 567: 566: 561: 549: 548: 547: 542: 529: 527: 515: 506: 495: 486: 478: 477: 475: 474: 473: 472: 467: 462: 457: 452: 447: 442: 431: 429: 428: 421: 414: 406: 399: 398: 391: 373: 366: 349: 306: 299: 281: 224: 217: 199: 172:(1–2): 11–16. 166:Mycopathologia 156: 139: 137: 134: 112: 105: 90: 89: 84: 79: 74: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 1793: 1782: 1779: 1778: 1776: 1761: 1753: 1752: 1749: 1743: 1740: 1739: 1736: 1726: 1723: 1721: 1718: 1716: 1713: 1711: 1708: 1704: 1701: 1699: 1696: 1695: 1694: 1691: 1690: 1688: 1684: 1679: 1674: 1668: 1665: 1663: 1660: 1658: 1657:Samandaridine 1655: 1653: 1650: 1648: 1645: 1643: 1640: 1638: 1635: 1631: 1630:Marinobufagin 1628: 1626: 1623: 1621: 1618: 1616: 1613: 1611: 1608: 1607: 1606: 1603: 1601: 1600:Batrachotoxin 1598: 1596: 1593: 1592: 1590: 1586: 1581: 1575: 1572: 1570: 1567: 1566: 1564: 1560: 1555: 1552: 1548: 1544: 1534: 1531: 1529: 1526: 1524: 1521: 1519: 1516: 1514: 1511: 1510: 1508: 1504: 1499: 1493: 1490: 1488: 1485: 1483: 1480: 1478: 1475: 1473: 1470: 1468: 1465: 1461: 1458: 1457: 1456: 1453: 1452: 1450: 1446: 1441: 1435: 1432: 1430: 1427: 1425: 1422: 1420: 1417: 1415: 1412: 1410: 1407: 1405: 1402: 1400: 1397: 1395: 1392: 1390: 1387: 1385: 1382: 1380: 1377: 1375: 1372: 1370: 1367: 1365: 1362: 1360: 1357: 1355: 1354:Charybdotoxin 1352: 1350: 1347: 1346: 1344: 1340: 1335: 1332: 1328: 1324: 1318: 1315: 1311: 1308: 1306: 1303: 1302: 1301: 1298: 1296: 1293: 1291: 1288: 1286: 1283: 1281: 1278: 1276: 1273: 1271: 1268: 1266: 1265:Solauricidine 1263: 1261: 1258: 1256: 1253: 1251: 1248: 1246: 1243: 1241: 1238: 1236: 1233: 1231: 1228: 1226: 1223: 1221: 1218: 1216: 1213: 1211: 1210:Protoanemonin 1208: 1206: 1203: 1201: 1198: 1196: 1195:Oenanthotoxin 1193: 1191: 1188: 1186: 1183: 1181: 1178: 1176: 1173: 1171: 1168: 1166: 1163: 1161: 1158: 1156: 1153: 1151: 1148: 1146: 1143: 1141: 1138: 1136: 1133: 1131: 1128: 1126: 1123: 1121: 1118: 1116: 1113: 1111: 1108: 1106: 1103: 1102: 1100: 1097: 1093: 1087: 1084: 1082: 1079: 1077: 1074: 1072: 1071:Trichothecene 1069: 1067: 1064: 1062: 1059: 1057: 1054: 1052: 1049: 1047: 1044: 1042: 1039: 1037: 1034: 1032: 1031:Ibotenic acid 1029: 1027: 1024: 1021: 1017: 1013: 1009: 1006: 1004: 1001: 999: 996: 994: 991: 989: 986: 983: 979: 975: 974:beta-amanitin 971: 967: 964: 962: 959: 958: 956: 954: 950: 940: 937: 935: 932: 931: 929: 927: 921: 913: 910: 908: 905: 904: 902: 898: 894: 891: 889: 886: 885: 884: 882: 878: 874: 871: 870: 869: 866: 865: 863: 861: 857: 845: 841: 838: 837: 836: 835: 831: 827: 824: 823: 822: 821: 817: 813: 810: 809: 808: 807: 803: 802: 800: 798: 794: 788: 785: 783: 780: 778: 775: 773: 769: 768:Cholera toxin 766: 764: 762: 758: 755: 752: 751: 749: 747: 741: 731: 728: 726: 723: 722: 720: 718: 714: 704: 701: 699: 696: 694: 691: 689: 685: 681: 678: 677: 675: 672: 667: 659: 656: 655: 654: 651: 649: 646: 645: 642: 639: 637: 633: 623: 620: 618: 617:Anthrax toxin 615: 614: 612: 606: 598: 595: 594: 593: 592: 588: 584: 581: 579: 576: 575: 574: 573: 569: 565: 562: 560: 557: 556: 555: 554: 550: 546: 543: 541: 540:Tetanospasmin 538: 537: 536: 535: 531: 530: 528: 524: 519: 516: 514: 510: 507: 505: 499: 496: 494: 490: 487: 485: 479: 471: 468: 466: 463: 461: 458: 456: 453: 451: 448: 446: 443: 441: 438: 437: 436: 433: 432: 427: 422: 420: 415: 413: 408: 407: 404: 394: 392:0-271-00442-8 388: 384: 377: 374: 369: 367:1-58808-162-1 363: 359: 353: 350: 345: 341: 337: 333: 329: 325: 321: 317: 310: 307: 302: 300:92-4-157219-1 296: 292: 285: 282: 277: 273: 268: 263: 259: 255: 251: 247: 244:(5): 1622–9. 243: 239: 235: 228: 225: 220: 218:0-306-45216-2 214: 210: 203: 200: 195: 191: 187: 183: 179: 175: 171: 167: 160: 157: 153: 149: 144: 141: 135: 133: 131: 126: 124: 123: 118: 117:trichothecene 110: 106: 104: 102: 96: 93: 88: 85: 83: 80: 78: 75: 73: 70: 69: 68: 65: 63: 62:sphingolipids 59: 55: 51: 50: 46:derived from 45: 41: 32: 19: 1741: 1720:Calcicludine 1710:Calciseptine 1693:Bungarotoxin 1662:Tarichatoxin 1610:Arenobufagin 1574:Tetrodotoxin 1533:Tetrodotoxin 1487:Vanillotoxin 1424:Phaiodotoxin 1327:Invertebrate 1250:Solasodamine 1185:Lotaustralin 1020:Fumonisin B4 1016:Fumonisin B2 1012:Fumonisin B1 1007: 998:Cytochalasin 900: 880: 832: 818: 812:Superantigen 804: 760: 648:Streptolysin 589: 570: 551: 532: 382: 376: 357: 352: 319: 315: 309: 290: 284: 241: 237: 227: 208: 202: 169: 165: 159: 143: 127: 120: 114: 108: 100: 97: 94: 91: 87:Fumonisin B4 82:Fumonisin B3 77:Fumonisin B2 72:Fumonisin B1 66: 47: 39: 37: 1683:Snake venom 1637:Epibatidine 1625:Cinobufagin 1482:Stromatoxin 1429:Imperatoxin 1379:Scyllatoxin 1285:Tagetitoxin 1280:Swainsonine 1270:Solauricine 1235:Solamargine 1230:Scopolamine 1220:Retronecine 1086:Zearalenone 754:Shiga toxin 725:Cord factor 564:Enterotoxin 559:Alpha toxin 553:perfringens 545:Tetanolysin 523:Clostridium 460:hepatotoxin 450:enterotoxin 440:cardiotoxin 130:zearalenone 58:sphinganine 1781:Mycotoxins 1715:Taicatoxin 1652:Samandarin 1605:Bufotoxins 1569:Ciguatoxin 1547:Vertebrate 1492:Huwentoxin 1472:Cupiennins 1455:Latrotoxin 1399:Kaliotoxin 1369:Margatoxin 1359:Maurotoxin 1300:Toxalbumin 1290:Tinyatoxin 1275:Strychnine 1260:Solasonine 1255:Solasodine 1240:Solanidine 1160:Falcarinol 1145:Delphinine 1061:Phalloidin 1051:Ochratoxin 1046:Orellanine 1036:Lolitrem B 1003:Ergotamine 953:Mycotoxins 797:Mechanisms 756:/Verotoxin 693:Exfoliatin 653:Leukocidin 470:phototoxin 465:neurotoxin 148:Fumonisins 136:References 52:and their 44:mycotoxins 40:fumonisins 18:Fumonisins 1620:Bufotenin 1615:Bufotalin 1585:Amphibian 1528:Saxitoxin 1518:Eledoisin 1513:Conotoxin 1384:Hefutoxin 1200:Oleandrin 1180:Linamarin 1170:Helenalin 1130:Cicutoxin 1125:Chaconine 1105:Amygdalin 1076:Vomitoxin 1026:Gliotoxin 1008:Fumonisin 961:Aflatoxin 924:Virulence 860:Endotoxin 591:botulinum 572:difficile 482:Bacterial 455:hemotoxin 445:cytotoxin 1775:Category 1760:Category 1523:Onchidal 1503:Mollusca 1414:Bestoxin 1409:Birtoxin 1374:Slotoxin 1364:Agitoxin 1339:Scorpion 1295:Tomatine 1245:Solanine 1190:Mimosine 1165:Gossypol 1150:Divicine 1115:Antiarin 1110:Anisatin 1041:Muscimol 993:Citrinin 966:Amatoxin 912:Cry34Ab1 840:AB toxin 834:type III 746:negative 504:positive 493:Exotoxin 344:26467225 276:17209063 194:12066786 122:Fusarium 109:Fusarium 49:Fusarium 1678:Reptile 1140:Daphnin 1135:Coniine 1120:Brucine 1081:Zeranol 1056:Patulin 903:toxins 893:Cry3Bb1 873:Lipid A 820:type II 761:E. coli 513:Bacilli 324:Bibcode 267:1828766 246:Bibcode 186:1513367 54:Liseola 1550:toxins 1445:Spider 1419:BmKAEP 1389:HgeTx1 1330:toxins 1205:Persin 1098:toxins 926:factor 907:Cry6Aa 899:Other 888:Cry1Ac 806:type I 609:Other: 534:tetani 484:toxins 435:Toxins 389:  364:  342:  297:  274:  264:  215:  192:  184:  154:(MeSH) 111:toxins 107:Other 1477:PhTx3 1394:HsTx1 1317:Tutin 1310:Ricin 1305:Abrin 1175:Ledol 1096:Plant 688:delta 636:Cocci 597:Botox 190:S2CID 1559:Fish 1467:CSTX 744:Gram 684:beta 502:Gram 387:ISBN 362:ISBN 340:PMID 295:ISBN 272:PMID 213:ISBN 182:PMID 115:The 38:The 1434:Pi3 1404:Lq2 844:AB5 332:doi 262:PMC 254:doi 174:doi 170:117 1777:: 1014:, 980:, 976:, 972:, 338:. 330:. 320:29 318:. 270:. 260:. 252:. 242:73 240:. 236:. 188:. 180:. 168:. 64:. 1685:: 1680:/ 1587:: 1561:: 1505:: 1447:: 1341:: 1022:) 1010:( 984:) 968:( 842:/ 770:/ 686:/ 682:/ 583:B 578:A 525:: 425:e 418:t 411:v 395:. 370:. 346:. 334:: 326:: 303:. 278:. 256:: 248:: 221:. 196:. 176:: 20:)

Index

Fumonisins

mycotoxins
Fusarium
Liseola
sphinganine
sphingolipids
Fumonisin B1
Fumonisin B2
Fumonisin B3
Fumonisin B4
trichothecene
Fusarium
zearalenone
Fumonisins
Medical Subject Headings
doi
10.1007/BF00497273
PMID
1513367
S2CID
12066786
ISBN
0-306-45216-2
"Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene"
Bibcode
2007ApEnM..73.1622I
doi
10.1128/aem.01077-06
PMC

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