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during transit. This testing involves repeatedly dropping a sample of tablets over a fixed time, using a rotating wheel with a baffle. The result is inspected for broken tablets, and the percentage of tablet mass lost through chipping. A typical specification will allow a non-zero percentage of
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in medicine. This is an important determination because tumors that are easily torn apart have a higher risk of malignancy and
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A friable substance is any substance that can be reduced to fibers or finer particles by the action of a small amount of
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UK Advisory
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foams, show an increase in friability with exposure to
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