Knowledge (XXG)

Gary H. Posner

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91:. Posner has also contributed numerous other developments in synthetic organic chemistry including asymmetric synthesis and multicomponent organic reactions. Posner's recent research has been focused on applying organic synthesis to the preparation of novel medicinal agents including 280:
Posner, Gary H.; Cho, C.-G.; Green, Julianne V.; Zhang, Yuesheng; Talalay, Paul (1994). "Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes".
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Posner, Gary H.; Parker, Michael H.; Northrop, John; Elias, Jeffrey S.; Ploypradith, Poonsakdi; Xie, Suji; Shapiro, Theresa A. (1999). "Orally Active, Hydrolytically Stable, Semisynthetic, Antimalarial Trioxanes in the Artemisinin Family".
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Posner, Gary H.; Canella, Karen A.; Silversmith, Ernest F. (1988). "One-pot, three-component, sequential Michael-Michael-ring-closure reactions. Annulation of meta-dicarboxylated aromatic rings. Total synthesis of juncunol".
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Posner, Gary H.; Paik, Ik-Hyeon; Chang, Wonsuk; Borstnik, Kristina; Sinishtaj, Sandra; Rosenthal, Andrew S.; Shapiro, Theresa A. (2007). "Malaria-Infected Mice Are Cured by a Single Dose of Novel Artemisinin Derivatives".
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In 1987, Posner was named Maryland Chemist of the Year and in 1994 he received the Distinguished Teaching Award at Johns Hopkins. He was also a 2004 recipient of a Cope Senior Scholar Award from the
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Guyton, Kathryn Z.; Kensler, Thomas W.; Posner, Gary H. (2004). "Chemopreventive Efficacy of Natural Vitamin D and Synthetic Analogs".
594: 228: 195: 64: 67:. He was at Johns Hopkins University from 1969 to 2016, where he held the Scowe Professorship in Chemistry from 1989 onwards. 402:
O'Neill, Paul M.; Posner, Gary H. (2004). "A Medicinal Chemistry Perspective on Artemisinin and Related Endoperoxides".
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Seeman, Jeffrey I. (2016). "Gary H. Posner: Professor, Scientist, Colleague, Role Model, and Friend".
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Posner, Gary H. (1972). "Conjugate Addition Reactions of Organocopper Reagents".
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Posner, Gary H. (1975). "Substitution Reactions Using Organocopper Reagents".
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Overview: rational design of 1α,25-dihydroxyvitamin D3 analogs (Deltanoids)
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Renowned chemist, longtime Hopkins faculty member Gary Posner dies at 74
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chemistry, including his involvement in the development of the
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analogs for the treatment of psoriasis, and new antimalarial
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An Introduction to Synthesis Using Organocopper Reagents
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Posner was first known for his pioneering research in
504:"Malaria-infected mice cured by 1 dose of new drug" 31:. Posner is known for his pioneering research in 167:Jean and Norman Scowe Professorship in Chemistry 140:The Robert A. Welch Foundation Research Bulletin 8: 63:. He did a post-doctoral fellowship at the 51:and completed his undergraduate studies at 79:in which he developed novel methods for 162: 160: 124: 351: 341: 37:Corey–House–Posner–Whitesides reaction 7: 130: 128: 87:. He is the author of the textbook 320:. Vol. 2. pp. 1405–1422. 215:. Vol. 22. pp. 253–400. 14: 373:. Vol. 1. pp. 259–274. 65:University of California Berkeley 600:Johns Hopkins University faculty 326:10.1016/B978-012252687-9/50084-X 182:. Vol. 19. pp. 1–113. 95:with anticancer properties, new 510:(Press release). 17 April 2007. 316:Posner, G; Kahraman, M (2005). 476:Journal of Medicinal Chemistry 440:Journal of Medicinal Chemistry 404:Journal of Medicinal Chemistry 283:Journal of Medicinal Chemistry 59:in 1968 where his adviser was 1: 605:Scientists from New York City 523:Arthur C. Cope Scholar Awards 379:10.1007/978-1-59259-767-3_17 247:Journal of Chemical Sciences 221:10.1002/0471264180.or022.02 188:10.1002/0471264180.or019.01 55:. He received his PhD from 621: 595:Harvard University alumni 563:10.1016/j.tet.2016.06.053 534:American Chemical Society 113:American Chemical Society 21:Johns Hopkins University 83:involving organocopper 371:Cancer Chemoprevention 77:organocopper chemistry 295:10.1021/jm00027a021 53:Brandeis University 47:Posner was born in 528:2011-08-11 at the 259:10.1007/BF02839442 57:Harvard University 590:American chemists 557:(40): 5950–5955. 488:10.1021/jm070149m 452:10.1021/jm980529v 416:10.1021/jm030571c 410:(12): 2945–2964. 388:978-1-61737-342-8 335:978-0-12-252687-9 213:Organic Reactions 180:Organic Reactions 81:organic synthesis 612: 566: 536: 520: 514: 511: 499: 470: 464: 463: 434: 428: 427: 399: 393: 392: 366: 360: 359: 353: 349: 347: 339: 313: 307: 306: 277: 271: 270: 241: 235: 234: 208: 202: 201: 175: 169: 164: 155: 150: 144: 143: 136:"GARY H. POSNER" 132: 620: 619: 615: 614: 613: 611: 610: 609: 570: 569: 548: 545: 540: 539: 530:Wayback Machine 521: 517: 502: 472: 471: 467: 436: 435: 431: 401: 400: 396: 389: 368: 367: 363: 350: 340: 336: 315: 314: 310: 279: 278: 274: 243: 242: 238: 231: 210: 209: 205: 198: 177: 176: 172: 165: 158: 151: 147: 142:(46): 18. 1983. 134: 133: 126: 121: 109: 93:isothiocyanates 73: 45: 12: 11: 5: 618: 616: 608: 607: 602: 597: 592: 587: 582: 572: 571: 568: 567: 544: 543:External links 541: 538: 537: 515: 513: 512: 482:(10): 2516–9. 465: 446:(2): 300–304. 429: 394: 387: 361: 352:|journal= 334: 308: 272: 253:(2–3): 81–90. 236: 230:978-0471264187 229: 203: 197:978-0471264187 196: 170: 156: 145: 123: 122: 120: 117: 108: 105: 72: 69: 44: 41: 17:Gary H. Posner 13: 10: 9: 6: 4: 3: 2: 617: 606: 603: 601: 598: 596: 593: 591: 588: 586: 583: 581: 578: 577: 575: 564: 560: 556: 552: 547: 546: 542: 535: 531: 527: 524: 519: 516: 509: 505: 501: 500: 497: 493: 489: 485: 481: 477: 469: 466: 461: 457: 453: 449: 445: 441: 433: 430: 425: 421: 417: 413: 409: 405: 398: 395: 390: 384: 380: 376: 372: 365: 362: 357: 345: 337: 331: 327: 323: 319: 312: 309: 304: 300: 296: 292: 288: 284: 276: 273: 268: 264: 260: 256: 252: 248: 240: 237: 232: 226: 222: 218: 214: 207: 204: 199: 193: 189: 185: 181: 174: 171: 168: 163: 161: 157: 154: 149: 146: 141: 137: 131: 129: 125: 118: 116: 114: 106: 104: 102: 98: 94: 90: 86: 82: 78: 70: 68: 66: 62: 58: 54: 50: 49:New York City 42: 40: 38: 34: 30: 26: 22: 18: 554: 550: 518: 507: 479: 475: 468: 443: 439: 432: 407: 403: 397: 370: 364: 317: 311: 289:(1): 170–6. 286: 282: 275: 250: 246: 239: 212: 206: 179: 173: 148: 139: 110: 88: 74: 46: 33:organocopper 16: 15: 585:2018 deaths 580:1943 births 551:Tetrahedron 508:EurekAlert! 61:E. J. Corey 574:Categories 119:References 354:ignored ( 344:cite book 101:peroxides 97:vitamin D 25:Baltimore 526:Archived 496:17439113 424:15163175 267:91965184 85:reagents 71:Research 29:Maryland 460:9925735 303:8289191 494:  458:  422:  385:  332:  301:  265:  227:  194:  107:Awards 43:Career 263:S2CID 492:PMID 456:PMID 420:PMID 383:ISBN 356:help 330:ISBN 299:PMID 225:ISBN 192:ISBN 559:doi 484:doi 448:doi 412:doi 375:doi 322:doi 291:doi 255:doi 251:100 217:doi 184:doi 23:in 576:: 555:72 553:. 532:, 506:. 490:. 480:50 478:. 454:. 444:42 442:. 418:. 408:47 406:. 381:. 348:: 346:}} 342:{{ 328:. 297:. 287:37 285:. 261:. 249:. 223:. 190:. 159:^ 138:. 127:^ 115:. 103:. 39:. 27:, 565:. 561:: 498:. 486:: 462:. 450:: 426:. 414:: 391:. 377:: 358:) 338:. 324:: 305:. 293:: 269:. 257:: 233:. 219:: 200:. 186::

Index

Johns Hopkins University
Baltimore
Maryland
organocopper
Corey–House–Posner–Whitesides reaction
New York City
Brandeis University
Harvard University
E. J. Corey
University of California Berkeley
organocopper chemistry
organic synthesis
reagents
isothiocyanates
vitamin D
peroxides
American Chemical Society


"GARY H. POSNER"
Renowned chemist, longtime Hopkins faculty member Gary Posner dies at 74


Jean and Norman Scowe Professorship in Chemistry
doi
10.1002/0471264180.or019.01
ISBN
978-0471264187
doi
10.1002/0471264180.or022.02

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