29:
117:
It is not possible to completely prevent hypertrophic scars, so those with a history of them should inform their doctor or surgeon if they need surgery. For example, pressure garment therapy is a commonly used approach used to try and prevent hypertrophic scarring after a burn, but the effectiveness
101:
When a normal wound heals, the body produces new collagen fibers at a rate which balances the breakdown of old collagen. Hypertrophic scars are red to brown and thick and may be itchy or painful. They do not extend beyond the boundary of the original wound, but may continue to thicken for up to six
147:
Laser therapy is an approach that has been studied for treating hypertrophic scars. There is not enough evidence to determine if laser therapy is more effective than other treatments or if laser therapy leads to more harm than benefits as compared with no treatment or different kinds of treatment.
138:
is sometimes used to treat hypertrophic scars. Silicone gel sheets may improve the appearance of scars slightly compared with applying onion extract, and may reduce pain compared with no treatment with silicone gel sheets or pressure garments. It is uncertain whether silicone gel sheets are more
126:
Early hypertrophic scars should be treated with applied pressure and massage in the first 1.5–3 months. If necessary, silicone therapy should be applied later. Ongoing hypertrophy may be treated with corticosteroids injections. Surgical revision may be considered after 1 year.
592:
287:
102:
months. Hypertrophic scars usually improve over one or two years, but may cause distress due to their appearance or the intensity of the itching; they can also restrict movement if they are located close to a joint.
585:
311:
Harris, Isobel M.; Lee, Kwang Chear; Deeks, Jonathan J.; Moore, David J.; Moiemen, Naiem S.; Dretzke, Janine (2024-01-08). "Pressure-garment therapy for preventing hypertrophic scarring after burn injury".
578:
1074:
923:
913:
1122:
540:
Zouboulis CC, Blume U, BĂĽttner P, Orfanos CE (September 1993). "Outcomes of cryosurgery in keloids and hypertrophic scars. A prospective consecutive trial of case series".
491:
Leszczynski, Rafael; da Silva, Carolina AP; Pinto, Ana
Carolina Pereira Nunes; Kuczynski, Uliana; da Silva, Edina MK (2022-09-26). Cochrane Wounds Group (ed.).
78:, cuts and burns. They often contain nerves and blood vessels. They generally develop after thermal or traumatic injury that involves the deep layers of the
686:
1335:
927:
898:
720:
703:
772:
757:
1057:
1219:
239:
Yagmur C, Akaishi S, Ogawa R, Guneren E (August 2010). "Mechanical receptor-related mechanisms in scar management: a review and hypothesis".
223:
196:
747:
1187:
28:
1199:
1301:
1194:
1132:
1242:
876:
1182:
1050:
691:
1257:
1247:
1229:
871:
159:, using extreme cold to remove dead tissue, may speed up the healing process from a hypertrophic scar to a flatter, paler one.
866:
861:
681:
1214:
1084:
1069:
886:
762:
1061:
881:
629:
168:
1204:
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908:
807:
676:
671:
653:
106:
624:
1079:
1025:
696:
619:
393:
Cooper JS, Lee BT (December 2009). "Treatment of facial scarring: lasers, filler, and nonoperative techniques".
1252:
641:
636:
1209:
997:
937:
742:
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893:
825:
752:
135:
570:
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59:
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856:
418:
264:
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802:
792:
557:
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375:
341:
329:
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219:
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95:
41:
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955:
787:
549:
512:
504:
460:
452:
402:
337:
321:
248:
553:
105:
Some people have an inherited tendency to hypertrophic scarring, for example, those with
777:
711:
517:
492:
465:
440:
439:
Jiang Q, Chen J, Tian F, Liu Z, et al. (Cochrane Wounds Group) (September 2021).
1329:
1310:
1296:
1237:
767:
422:
75:
268:
1164:
980:
508:
456:
325:
98:
on a wound has been identified as a leading cause for hypertrophic scar formation.
252:
1099:
970:
835:
615:
156:
46:
1177:
607:
333:
848:
839:
662:
647:
526:
474:
414:
406:
379:
363:
345:
260:
561:
218:. Handbook of Burns. Vol. 1. Springer Science & Business Media.
83:
63:
1159:
1104:
71:
1306:
1019:
975:
815:
727:
79:
797:
67:
574:
74:. Like keloids, they form most often at the sites of pimples,
212:
Jeschke MG, Kamolz LP, Sjöberg F, Wolf SE (23 August 2012).
493:"Laser therapy for treating hypertrophic and keloid scars"
441:"Silicone gel sheeting for treating hypertrophic scars"
601:
Cutaneous keratosis, ulcer, atrophy, and necrobiosis
1284:
1266:
1228:
1158:
1098:
1033:
1018:
989:
936:
914:
Palisaded neutrophilic and granulomatous dermatitis
847:
834:
606:
40:
21:
1075:Lupus erythematosus–lichen planus overlap syndrome
62:characterized by deposits of excessive amounts of
1123:Morphea–lichen sclerosus et atrophicus overlap
364:"Management of keloids and hypertrophic scars"
586:
8:
139:effective than other treatment approaches.
445:The Cochrane Database of Systematic Reviews
314:The Cochrane Database of Systematic Reviews
187:Rapini RP, Bolognia JL, Jorizzo JL (2007).
36:Hypertrophic scar (4 months after incident)
1030:
844:
593:
579:
571:
362:Juckett G, Hartman-Adams H (August 2009).
27:
18:
687:Seborrheic keratosis with squamous atypia
516:
464:
928:Interstitial granulomatous drug reaction
899:Annular elastolytic giant-cell granuloma
721:Confluent and reticulated papillomatosis
704:Keratosis punctata of the palmar creases
773:Multiple minute digitate hyperkeratosis
758:Hyperkeratosis of the nipple and areola
497:Cochrane Database of Systematic Reviews
179:
630:Acrokeratosis paraneoplastica of Bazex
70:, but not to the degree observed with
1220:Atrophia maculosa varioliformis cutis
924:Interstitial granulomatous dermatitis
7:
748:Hyperkeratosis lenticularis perstans
554:10.1001/archderm.1993.01680300074011
486:
484:
434:
432:
357:
355:
1200:Acrodermatitis chronica atrophicans
1302:Poikiloderma vasculare atrophicans
1195:Atrophoderma of Pasini and Pierini
1133:Atrophoderma of Pasini and Pierini
241:Plastic and Reconstructive Surgery
14:
1243:Reactive perforating collagenosis
877:Granuloma annulare in HIV disease
692:Reticulated seborrheic keratosis
1336:Dermal and subcutaneous growths
1258:Acquired perforating dermatosis
1248:Elastosis perforans serpiginosa
1188:Jadassohn–Pellizzari anetoderma
682:Irritated seborrheic keratosis
509:10.1002/14651858.CD011642.pub2
457:10.1002/14651858.CD013357.pub2
326:10.1002/14651858.CD013530.pub2
1:
1215:Linear atrophoderma of Moulin
887:Patch-type granuloma annulare
763:Inverted follicular keratosis
118:of this approach is unclear.
66:which gives rise to a raised
1183:Schweninger–Buzzi anetoderma
882:Localized granuloma annulare
253:10.1097/PRS.0b013e3181df715d
169:List of cutaneous conditions
909:Necrobiotic xanthogranuloma
808:Waxy keratosis of childhood
677:Common seborrheic keratosis
672:Clonal seborrheic keratosis
654:Keratoderma blennorrhagicum
82:and express high levels of
1357:
625:Paraneoplastic keratoderma
697:Dermatosis papulosa nigra
620:Keratoderma climactericum
368:American Family Physician
189:Dermatology: 2-Volume Set
35:
26:
1253:Perforating folliculitis
1205:Semicircular lipoatrophy
642:Drug-induced keratoderma
1210:Follicular atrophoderma
998:eosinophilic dermatosis
542:Archives of Dermatology
938:Foreign body granuloma
849:Necrobiotic/palisading
743:Chronic scar keratosis
407:10.1055/s-0029-1243079
395:Facial Plastic Surgery
107:Ehlers–Danlos syndrome
1113:Localized scleroderma
894:Necrobiosis lipoidica
826:Cutis verticis gyrata
753:Hydrocarbon keratosis
637:Aquagenic keratoderma
277:(2012) page 332.
136:Silicone gel sheeting
131:Silicone gel sheeting
1276:Pyoderma gangrenosum
1138:Pansclerotic morphea
919:Rheumatoid nodulosis
904:Granuloma multiforme
783:Reactional keratosis
733:Ichthyosis acquisita
716:Acanthosis nigricans
667:Seborrheic keratosis
608:Epidermal thickening
191:. St. Louis: Mosby.
1128:Generalized morphea
966:Zirconium granuloma
946:Beryllium granuloma
814:other hypertrophy:
768:Lichenoid keratosis
738:Arsenical keratosis
60:cutaneous condition
1148:Linear scleroderma
961:Silicone granuloma
857:Granuloma annulare
1323:
1322:
1319:
1318:
1118:Localized morphea
1090:Rowell's syndrome
1014:
1013:
1004:Granuloma faciale
951:Mercury granuloma
821:Hypertrophic scar
803:Warty dyskeratoma
793:Thermal keratosis
225:978-3-7091-0348-7
198:978-1-4160-2999-1
56:hypertrophic scar
52:
51:
22:Hypertrophic scar
16:Medical condition
1348:
1292:Calcinosis cutis
1173:Lichen sclerosus
1143:Morphea profunda
1031:
956:Silica granuloma
845:
788:Stucco keratosis
595:
588:
581:
572:
566:
565:
548:(9): 1146–1151.
537:
531:
530:
520:
488:
479:
478:
468:
436:
427:
426:
390:
384:
383:
359:
350:
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340: 10772976.
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292:www.uptodate.com
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1315:
1280:
1262:
1224:
1163:
1154:
1103:
1094:
1036:
1035:Cutaneous lupus
1023:
1010:
990:Other/ungrouped
985:
932:
830:
798:Viral keratosis
602:
599:
569:
539:
538:
534:
503:(9): CD011642.
490:
489:
482:
451:(9): CD013357.
438:
437:
430:
392:
391:
387:
361:
360:
353:
320:(1): CD013530.
310:
309:
305:
296:
294:
286:
285:
281:
275:Acute Burn Care
238:
237:
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226:
215:Acute Burn Care
211:
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92:
17:
12:
11:
5:
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921:
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869:
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832:
831:
829:
828:
823:
818:
811:
810:
805:
800:
795:
790:
785:
780:
778:PUVA keratosis
775:
770:
765:
760:
755:
750:
745:
740:
735:
730:
725:
724:
723:
712:hyperkeratosis
707:
706:
701:
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694:
689:
684:
679:
674:
659:
658:
657:
656:
644:
639:
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612:
610:
604:
603:
600:
598:
597:
590:
583:
575:
568:
567:
532:
480:
428:
401:(5): 311–315.
385:
374:(3): 253–260.
351:
303:
279:
247:(2): 426–434.
231:
224:
204:
197:
178:
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173:
172:
171:
164:
161:
153:
150:
144:
141:
132:
129:
123:
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114:
111:
91:
88:
76:body piercings
50:
49:
44:
38:
37:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1353:
1342:
1339:
1337:
1334:
1333:
1331:
1312:
1311:Pseudo-ainhum
1308:
1305:
1303:
1300:
1298:
1297:Sclerodactyly
1295:
1293:
1290:
1289:
1287:
1283:
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1273:
1271:
1269:
1265:
1259:
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1251:
1249:
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1244:
1241:
1239:
1238:Kyrle disease
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1038:
1037:erythematosus
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143:Laser therapy
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73:
69:
65:
61:
57:
48:
45:
43:
39:
34:
30:
25:
20:
1165:atrophoderma
1051:Panniculitis
996:
981:Carbon stain
872:Subcutaneous
820:
646:
545:
541:
535:
500:
496:
448:
444:
398:
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295:. Retrieved
291:
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188:
182:
155:
146:
134:
125:
116:
104:
100:
93:
55:
53:
1230:Perforating
1100:Scleroderma
1068:ungrouped:
971:Soot tattoo
867:Generalized
862:Perforating
836:Necrobiosis
616:keratoderma
157:Cryosurgery
152:Cryosurgery
94:Mechanical
47:Dermatology
1330:Categories
1268:Skin ulcer
1178:Anetoderma
1044:chronic:
1024:localized
297:2024-05-29
288:"UpToDate"
175:References
122:Management
113:Prevention
1085:Verrucous
1070:Chilblain
840:granuloma
663:keratosis
648:psoriasis
423:260136591
334:1469-493X
273:cited in
42:Specialty
1341:Scarring
1160:Atrophic
1062:Neonatal
1058:subacute
527:36161591
475:34564840
415:20024872
380:19621835
346:38189494
269:23828914
261:20375759
163:See also
64:collagen
1105:Morphea
1046:Discoid
562:8363398
518:9511989
466:8464654
96:tension
72:keloids
1307:Ainhum
1020:Dermis
976:Tattoo
816:Keloid
728:Callus
710:other
560:
525:
515:
473:
463:
421:
413:
378:
344:
332:
267:
259:
222:
195:
80:dermis
1285:Other
1080:Tumid
419:S2CID
265:S2CID
90:Cause
84:TGF-β
58:is a
558:PMID
523:PMID
501:2022
471:PMID
449:2021
411:PMID
376:PMID
342:PMID
330:ISSN
257:PMID
220:ISBN
193:ISBN
68:scar
1026:CTD
550:doi
546:129
513:PMC
505:doi
461:PMC
453:doi
403:doi
338:PMC
322:doi
249:doi
245:126
1332::
1060::
714::
665::
618::
556:.
544:.
521:.
511:.
499:.
495:.
483:^
469:.
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431:^
417:.
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399:25
397:.
372:80
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366:.
354:^
336:.
328:.
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290:.
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255:.
243:.
109:.
86:.
54:A
1309:/
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594:e
587:t
580:v
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552::
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507::
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405::
382:.
348:.
324::
318:1
300:.
271:.
251::
228:.
201:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
