144:, meningitis caused by pathogens other than bacteria, is the most common form of meningitis with an estimate of 70 cases per 100,000 patients less than 1 year old, 5.2 cases per 100,000 patients 1 to 14 years of age, and 7.6 cases per 100,000 adults. When looking at the most common causes of meningitis, 8.3% are due to herpes simplex virus. HSV-2 specifically is the most common cause of meningitis in adults.
192:
Differential diagnoses are broad including other causes of meningitis (bacterial, fungal, drug-induced), systemic infection, vasculitis, auto-immune disease, and cancer. As such, patient presentation of fever, headache, stiff neck, and altered mental status is not sufficient information for diagnosis
221:
HSV-2 is the most common herpes virus that causes meningitis. This virus is transmitted via sexual contact and there are currently no vaccinations or cures for the disease. At the moment, there are no specific programs developed to prevent HSV-2 spread and prevention of disease is primarily done via
217:
Although guidelines strongly recommend acyclovir for treatment of herpes encephalitis, there are currently no such guidelines for managing herpes meningitis. Herpes meningitis is typically self-limiting over 2 weeks without treatment. However, empirical use of antiviral medications such as acyclovir
155:
Common symptoms include nausea, vomiting, neck-stiffness, photophobia, and severe frontal headaches. Patients with meningitis secondary to the HSV-2 virus may also present with genital lesions, although most cases of HSV-2 meningitis occur without symptoms of genital herpes. Around one fifth of
31:
1068:
1053:
208:
is the gold standard for detection of herpes virus in patient CSF fluid due to high specificity and has been able to detect the HSV-2 virus in patients presenting without genital lesions as well as those experiencing recurrent meningitis.
113:
family - the most common amongst adults is HSV-2. Symptoms are self-limiting over 2 weeks with severe headache, nausea, vomiting, neck-stiffness, and photophobia. Herpes meningitis can cause
1688:
2244:
184:. Recurrences usually last a few days or a few weeks, and resolve without treatment. They may recur weekly or monthly for approximately 5 years following primary infection.
1111:
2123:
1702:
129:
is used to detect viral presence. Although symptoms are self-limiting, treatment with antiviral medication may be recommended to prevent progression to Herpes
1368:
1199:
1239:
1104:
589:
147:
Herpesviral meningitis primarily affects people aged 35–40, the elderly, and women. Between 20% and 50% of cases have clinical recurrences.
1332:
1389:
2116:
554:
Tyler KL (2004). "Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including
Mollaret's".
1708:
1234:
1191:
109:
is inflammation of the meninges, the protective tissues surrounding the spinal cord and brain, due to infection from viruses of the
1623:
977:"Epidemiological Impact of Novel Preventive and Therapeutic HSV-2 Vaccination in the United States: Mathematical Modeling Analyses"
1694:
1097:
218:
are considered in cases of suspected HSV meningitis to prevent progression to the more rapid and fatal HSV meningoencephalitis.
2205:
48:
1293:
1279:
2109:
1498:
1492:
1403:
1397:
1287:
1861:
1787:
1781:
1454:
201:
findings in herpes meningitis present with lymphocytic pleocytosis, normal glucose, and normal-to-elevated protein.
156:
people infected with HSV-2 have symptoms of meningitis with their initial infection, more commonly men than women.
1918:
1525:
205:
126:
1627:
1539:
1444:
1274:
1247:
1219:
1152:
231:
165:
114:
1423:
1617:
1213:
92:
Bacterial meningitis, viral meningitis, fungal meningitis, drug-induced meningitis, CNS abscess, vasculitis
2181:
2169:
2164:
2159:
1817:
1795:
1674:
1670:
1666:
1662:
1555:
1449:
1410:
170:
87:
1802:
1383:
1253:
928:
Noska, Amanda; Kyrillos, Ramona; Hansen, Glen; Hirigoyen, Diane; Williams, David N. (January 15, 2015).
1224:
222:
behavioral modification via condom use or through application of antiviral medications upon infection.
2154:
2066:
1898:
1533:
1362:
2249:
2223:
1484:
1205:
1072:
198:
130:
122:
930:"The role of antiviral therapy in immunocompromised patients with herpes simplex virus meningitis"
2200:
1587:
1343:
742:
531:
141:
59:
1089:
695:
649:"Herpes simplex virus and central nervous system infections: encephalitis, meningitis, myelitis"
2188:
2051:
2002:
1983:
1964:
1754:
1750:
1746:
1742:
1659:
1564:
1268:
1146:
1016:
998:
957:
949:
910:
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850:
801:
762:
723:
715:
676:
668:
629:
621:
585:
559:
523:
515:
473:
455:
409:
391:
347:
329:
290:
272:
77:
43:
696:"Genital Herpes Simplex Virus Infections: Clinical Manifestations, Course, and Complications"
2176:
2101:
2026:
1736:
1416:
1348:
1229:
1160:
1006:
988:
941:
900:
884:
840:
832:
793:
754:
707:
660:
507:
463:
447:
399:
383:
337:
321:
280:
264:
1950:
1878:
1873:
1855:
1775:
1764:
1635:
1599:
1519:
1305:
1166:
194:
181:
118:
495:
451:
38:
T1W MRI of the brain demonstrating leptomeningeal enhancement consistent with meningitis
2193:
1186:
1011:
976:
845:
820:
468:
435:
404:
371:
325:
285:
252:
1077:
905:
872:
342:
309:
2238:
2149:
1181:
1176:
1124:
781:
535:
110:
2042:
1892:
1570:
1431:
873:"Aseptic meningitis and encephalitis: the role of PCR in the diagnostic laboratory"
888:
758:
743:"Herpes Simplex Type-2 Meningitis: Presentation and Lack of Standardized Therapy"
511:
251:
Kohil, Amira; Jemmieh, Sara; Smatti, Maria K.; Yassine, Hadi M. (February 2021).
2082:
2031:
2019:
2014:
2007:
1995:
1990:
1969:
1939:
1841:
1680:
1592:
1575:
1510:
1171:
387:
178:
125:
results demonstrating aseptic meningitis pattern is necessary for diagnosis and
711:
268:
2141:
2132:
1932:
1716:
1473:
1062:
797:
174:
1002:
953:
896:
805:
741:
Landry, Marie L.; Greenwold, Jennifer; Vikram, Holenarasipur R. (July 2009).
719:
672:
625:
519:
459:
395:
333:
276:
173:
is the most common cause of
Mollaret's meningitis, a type of recurrent viral
1977:
1958:
1925:
1913:
1907:
1886:
1832:
1760:
1731:
1654:
1646:
1608:
1377:
1356:
1262:
1140:
1132:
1120:
993:
975:
Ayoub, Houssein H.; Chemaitelly, Hiam; Abu-Raddad, Laith J. (July 8, 2020).
52:
30:
1020:
961:
929:
854:
766:
680:
633:
609:
563:
527:
477:
413:
351:
294:
914:
727:
664:
580:
Roberts, James R.; Custalow, Catherine B.; Thomsen, Todd W., eds. (2019).
2075:
1722:
1464:
1320:
945:
610:"Aseptic and Bacterial Meningitis: Evaluation, Treatment, and Prevention"
1045:
836:
648:
1828:
1437:
1057:
2088:
1847:
1479:
2105:
1093:
1314:
582:
Roberts and Hedges' clinical procedures in emergency medicine
308:
Spear, Patricia G.; Longnecker, Richard (October 2003).
608:
Mount, Hillary R.; Boyle, Sean D. (September 1, 2017).
177:. This condition was first described in 1944 by French
370:
Logan, Sarah A E; MacMahon, Eithne (January 5, 2008).
1035:
2216:
2140:
2065:
2041:
1949:
1872:
1827:
1816:
1645:
1607:
1586:
1554:
1509:
1463:
1342:
1331:
1304:
1131:
1039:
494:Gundamraj, Vaishnavi; Hasbun, Rodrigo (June 2023).
197:must be performed to properly diagnose meningitis.
96:
86:
76:
68:
58:
42:
23:
780:Rosenberg, Jon; Galen, Benjamin T. (July 2017).
489:
487:
436:"The management of acute meningitis: an update"
871:Read, S J; Jeffery, K J; Bangham, C R (1997).
575:
573:
549:
547:
545:
496:"Viral meningitis and encephalitis: an update"
434:Carter, Emma; McGill, Fiona (September 2022).
2117:
1105:
429:
427:
425:
423:
8:
866:
864:
603:
601:
584:(Seventh ed.). Philadelphia: Elsevier.
365:
363:
361:
64:Headache, fever, neck stiffness, photophobia
2124:
2110:
2102:
1824:
1604:
1369:Progressive multifocal leukoencephalopathy
1339:
1112:
1098:
1090:
1036:
29:
20:
1240:Extranodal NK/T-cell lymphoma, nasal type
1010:
992:
904:
844:
467:
403:
341:
284:
2245:Herpes simplex virus–associated diseases
243:
500:Current Opinion in Infectious Diseases
7:
1390:Subacute sclerosing panencephalitis
452:10.7861/clinmed.2022-cme-meningitis
72:Viruses of the herpesviridae family
326:10.1128/JVI.77.19.10179-10185.2003
117:, a form of recurrent meningitis.
14:
1709:Severe acute respiratory syndrome
1235:Follicular dendritic cell sarcoma
786:Current Pain and Headache Reports
647:Rozenberg, Flore (October 2020).
1695:Middle East respiratory syndrome
877:Journal of Clinical Microbiology
747:The American Journal of Medicine
694:Corey, Lawrence (June 1, 1983).
204:DNA analysis techniques such as
253:"Viral meningitis: an overview"
2135:and other diseases of meninges
1294:Adult T-cell leukemia/lymphoma
1280:Splenic marginal zone lymphoma
310:"Herpesvirus Entry: an Update"
100:Symptom management, antivirals
1:
889:10.1128/jcm.35.3.691-696.1997
82:CSF findings, lumbar puncture
1499:Tropical spastic paraparesis
1404:Lymphocytic choriomeningitis
934:Clinical Infectious Diseases
759:10.1016/j.amjmed.2009.02.017
512:10.1097/QCO.0000000000000922
1862:Cytomegalovirus esophagitis
1782:Human parainfluenza viruses
1455:Ramsay Hunt syndrome type 2
700:Annals of Internal Medicine
388:10.1136/bmj.39409.673657.AE
2266:
819:Sendi P, Graber P (2006).
712:10.7326/0003-4819-98-6-958
269:10.1007/s00705-020-04891-1
163:
159:
1526:Cytomegalovirus retinitis
798:10.1007/s11916-017-0635-7
614:American Family Physician
206:polymerase chain reaction
127:polymerase chain reaction
37:
28:
1628:Infectious mononucleosis
1445:Chandipura vesiculovirus
1275:Hepatocellular carcinoma
1220:Nasopharyngeal carcinoma
1153:Hepatocellular carcinoma
558:. 11. Suppl 2: 57A–64A.
232:Herpesviral encephalitis
1424:Encephalitis lethargica
1125:viral systemic diseases
994:10.3390/vaccines8030366
821:"Mollaret's meningitis"
1796:Human orthopneumovirus
1450:Herpesviral meningitis
1411:Arbovirus encephalitis
782:"Recurrent Meningitis"
88:Differential diagnosis
1254:Merkel-cell carcinoma
665:10.1684/vir.2020.0862
166:Mollaret's meningitis
160:Mollaret's Meningitis
151:Clinical presentation
115:Mollaret's meningitis
1899:Adenovirus infection
1363:Human polyomavirus 2
1192:Oropharyngeal cancer
257:Archives of Virology
2224:Meningoencephalitis
1485:Post-polio syndrome
1121:Infectious diseases
837:10.1503/cmaj.051688
320:(19): 10179–10185.
314:Journal of Virology
199:Cerebrospinal fluid
131:Meningoencephalitis
123:cerebrospinal fluid
1618:Epstein–Barr virus
1588:Respiratory system
1225:Burkitt's lymphoma
946:10.1093/cid/ciu772
372:"Viral meningitis"
142:Aseptic meningitis
49:Infectious disease
2232:
2231:
2099:
2098:
2061:
2060:
1812:
1811:
1743:Influenza virus A
1660:Human coronavirus
1550:
1549:
1540:Herpes of the eye
1087:
1086:
591:978-0-323-35478-3
440:Clinical Medicine
107:Herpes meningitis
104:
103:
78:Diagnostic method
24:Herpes meningitis
18:Medical condition
2257:
2126:
2119:
2112:
2103:
1825:
1820:digestive system
1737:Orthomyxoviridae
1703:SARS coronavirus
1689:MERS coronavirus
1605:
1417:Orthomyxoviridae
1340:
1306:Immune disorders
1230:Hodgkin lymphoma
1206:Kaposi's sarcoma
1114:
1107:
1100:
1091:
1037:
1025:
1024:
1014:
996:
972:
966:
965:
925:
919:
918:
908:
868:
859:
858:
848:
816:
810:
809:
777:
771:
770:
738:
732:
731:
691:
685:
684:
644:
638:
637:
605:
596:
595:
577:
568:
567:
551:
540:
539:
491:
482:
481:
471:
431:
418:
417:
407:
367:
356:
355:
345:
305:
299:
298:
288:
248:
33:
21:
2265:
2264:
2260:
2259:
2258:
2256:
2255:
2254:
2235:
2234:
2233:
2228:
2212:
2136:
2130:
2100:
2095:
2057:
2037:
1945:
1919:Gastroenteritis
1877:
1874:Gastroenteritis
1868:
1856:Cytomegalovirus
1819:
1808:
1776:Paramyxoviridae
1765:Avian influenza
1641:
1636:Cytomegalovirus
1600:viral pneumonia
1598:
1595:nasopharyngitis
1594:
1591:
1582:
1546:
1520:Cytomegalovirus
1505:
1459:
1347:
1334:
1327:
1300:
1167:Cervical cancer
1127:
1118:
1088:
1083:
1082:
1048:
1034:
1029:
1028:
974:
973:
969:
927:
926:
922:
870:
869:
862:
818:
817:
813:
779:
778:
774:
740:
739:
735:
693:
692:
688:
646:
645:
641:
607:
606:
599:
592:
579:
578:
571:
553:
552:
543:
493:
492:
485:
433:
432:
421:
382:(7634): 36–40.
369:
368:
359:
307:
306:
302:
250:
249:
245:
240:
228:
215:
195:lumbar puncture
190:
182:Pierre Mollaret
168:
162:
153:
139:
119:Lumbar puncture
19:
12:
11:
5:
2263:
2261:
2253:
2252:
2247:
2237:
2236:
2230:
2229:
2227:
2226:
2220:
2218:
2214:
2213:
2211:
2210:
2209:
2208:
2198:
2197:
2196:
2186:
2185:
2184:
2174:
2173:
2172:
2167:
2162:
2152:
2146:
2144:
2138:
2137:
2131:
2129:
2128:
2121:
2114:
2106:
2097:
2096:
2094:
2093:
2092:
2091:
2079:
2071:
2069:
2063:
2062:
2059:
2058:
2056:
2055:
2047:
2045:
2039:
2038:
2036:
2035:
2023:
2011:
1999:
1987:
1980:
1974:
1973:
1961:
1955:
1953:
1947:
1946:
1944:
1943:
1936:
1929:
1922:
1910:
1904:
1903:
1902:
1901:
1889:
1883:
1881:
1870:
1869:
1867:
1866:
1865:
1864:
1852:
1851:
1850:
1837:
1835:
1822:
1814:
1813:
1810:
1809:
1807:
1806:
1799:
1792:
1791:
1790:
1770:
1769:
1768:
1767:
1728:
1727:
1726:
1725:
1713:
1712:
1711:
1699:
1698:
1697:
1685:
1684:
1683:
1651:
1649:
1643:
1642:
1640:
1639:
1632:
1631:
1630:
1613:
1611:
1602:
1584:
1583:
1581:
1580:
1579:
1578:
1573:
1560:
1558:
1556:Cardiovascular
1552:
1551:
1548:
1547:
1545:
1544:
1543:
1542:
1530:
1529:
1528:
1515:
1513:
1507:
1506:
1504:
1503:
1502:
1501:
1489:
1488:
1487:
1482:
1469:
1467:
1461:
1460:
1458:
1457:
1452:
1447:
1442:
1441:
1440:
1428:
1427:
1426:
1413:
1408:
1407:
1406:
1394:
1393:
1392:
1380:
1374:
1373:
1372:
1371:
1359:
1353:
1351:
1337:
1335:nervous system
1329:
1328:
1326:
1325:
1324:
1323:
1310:
1308:
1302:
1301:
1299:
1298:
1297:
1296:
1284:
1283:
1282:
1277:
1265:
1259:
1258:
1257:
1256:
1244:
1243:
1242:
1237:
1232:
1227:
1222:
1210:
1209:
1208:
1196:
1195:
1194:
1189:
1187:Vaginal cancer
1184:
1179:
1174:
1169:
1157:
1156:
1155:
1143:
1137:
1135:
1129:
1128:
1119:
1117:
1116:
1109:
1102:
1094:
1085:
1084:
1081:
1080:
1065:
1049:
1044:
1043:
1041:
1040:Classification
1033:
1032:External links
1030:
1027:
1026:
967:
940:(2): 237–242.
920:
883:(3): 691–696.
860:
811:
772:
753:(7): 688–691.
733:
706:(6): 958–972.
686:
659:(5): 283–294.
639:
620:(5): 314–322.
597:
590:
569:
541:
506:(3): 177–185.
483:
446:(5): 396–400.
419:
357:
300:
263:(2): 335–345.
242:
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164:Main article:
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2171:
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2158:
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2151:
2150:Arachnoiditis
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2147:
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2139:
2134:
2127:
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2090:
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2070:
2068:
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2049:
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2044:
2040:
2033:
2029:
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2024:
2021:
2017:
2016:
2012:
2009:
2005:
2004:
2000:
1997:
1993:
1992:
1988:
1986:
1985:
1981:
1979:
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1971:
1967:
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1962:
1960:
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1911:
1909:
1906:
1905:
1900:
1897:
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1895:
1894:
1890:
1888:
1885:
1884:
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1880:
1875:
1871:
1863:
1860:
1859:
1858:
1857:
1853:
1849:
1846:
1845:
1844:
1843:
1839:
1838:
1836:
1834:
1830:
1826:
1823:
1821:
1815:
1805:
1804:
1800:
1798:
1797:
1793:
1789:
1788:Parainfluenza
1786:
1785:
1784:
1783:
1778:
1777:
1772:
1771:
1766:
1762:
1759:
1758:
1757:
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1752:
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1733:
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1724:
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1707:
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1705:
1704:
1700:
1696:
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1690:
1686:
1682:
1679:
1678:
1677:
1676:
1672:
1668:
1664:
1661:
1656:
1653:
1652:
1650:
1648:
1644:
1638:
1637:
1633:
1629:
1625:
1624:EBV infection
1622:
1621:
1620:
1619:
1615:
1614:
1612:
1610:
1606:
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1508:
1500:
1497:
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1483:
1481:
1480:Poliomyelitis
1478:
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1475:
1471:
1470:
1468:
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1456:
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1207:
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1203:
1202:
1201:
1197:
1193:
1190:
1188:
1185:
1183:
1182:Vulvar cancer
1180:
1178:
1177:Penile cancer
1175:
1173:
1170:
1168:
1165:
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1162:
1158:
1154:
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111:Herpesviridae
108:
99:
95:
91:
89:
85:
81:
79:
75:
71:
67:
63:
61:
57:
54:
50:
47:
45:
41:
36:
32:
27:
22:
16:
2206:Drug-induced
2194:Cryptococcal
2170:Pneumococcal
2081:
2074:
2050:
2043:Pancreatitis
2025:
2013:
2001:
1989:
1982:
1963:
1938:
1931:
1924:
1912:
1891:
1854:
1840:
1801:
1794:
1780:
1774:
1741:
1735:
1715:
1701:
1687:
1658:
1634:
1616:
1571:Pericarditis
1563:
1532:
1518:
1491:
1472:
1430:
1415:
1396:
1382:
1361:
1344:Encephalitis
1313:
1286:
1267:
1246:
1212:
1198:
1159:
1145:
1067:
1052:
984:
980:
970:
937:
933:
923:
880:
876:
831:(12): 1710.
828:
824:
814:
789:
785:
775:
750:
746:
736:
703:
699:
689:
656:
652:
642:
617:
613:
581:
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379:
375:
317:
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260:
256:
246:
220:
216:
203:
191:
169:
154:
146:
140:
137:Epidemiology
106:
105:
15:
2182:Herpesviral
2165:Haemophilus
2160:Tuberculous
1940:Coronavirus
1681:Common cold
1593:acute viral
1576:Myocarditis
1420:(probable)
1172:Anal cancer
179:neurologist
2250:Meningitis
2239:Categories
2142:Meningitis
2133:Meningitis
2067:Urogenital
1933:Astrovirus
1893:Adenovirus
1717:SARS-CoV-2
1474:Poliovirus
1349:meningitis
987:(3): 366.
238:References
175:meningitis
2155:Bacterial
1978:RNA virus
1959:DNA virus
1951:Hepatitis
1926:Norovirus
1914:Rotavirus
1908:RNA virus
1887:DNA virus
1833:Esophagus
1761:Influenza
1647:RNA virus
1609:DNA virus
1378:RNA virus
1357:DNA virus
1263:RNA virus
1141:DNA virus
1133:Oncovirus
1003:2076-393X
954:1537-6591
897:0095-1137
806:1531-3433
720:0003-4819
673:1267-8694
653:Virologie
626:1532-0650
536:258299272
520:0951-7375
460:1470-2118
396:0959-8138
334:0022-538X
277:0304-8608
213:Treatment
188:Diagnosis
97:Treatment
53:Neurology
44:Specialty
2076:BK virus
1879:diarrhea
1723:COVID-19
1465:Myelitis
1021:32650385
981:Vaccines
962:25273082
855:16754896
767:19559173
681:33111702
634:28925647
564:15319091
528:37093042
478:36507811
414:18174598
352:12970403
295:33392820
226:See also
60:Symptoms
2201:Aseptic
1829:Pharynx
1333:Central
1012:7564812
915:9041414
846:1471823
728:6344712
469:9594998
405:2174764
286:7779091
2189:Fungal
1493:HTLV-I
1438:Rabies
1288:HTLV-I
1019:
1009:
1001:
960:
952:
913:
906:229652
903:
895:
853:
843:
804:
765:
726:
718:
679:
671:
632:
624:
588:
562:
556:Herpes
534:
526:
518:
476:
466:
458:
412:
402:
394:
350:
343:228481
340:
332:
293:
283:
275:
69:Causes
2217:Other
2177:Viral
2089:Mumps
1848:Mumps
1818:Human
1248:MCPyV
1078:054.3
1063:B00.3
792:(7).
532:S2CID
171:HSV-2
121:with
1803:hMPV
1675:OC43
1671:HKU1
1667:NL63
1663:229E
1321:AIDS
1200:KSHV
1073:9-CM
1017:PMID
999:ISSN
958:PMID
950:ISSN
911:PMID
893:ISSN
851:PMID
825:CMAJ
802:ISSN
763:PMID
724:PMID
716:ISSN
677:PMID
669:ISSN
630:PMID
622:ISSN
586:ISBN
560:PMID
524:PMID
516:ISSN
474:PMID
456:ISSN
410:PMID
392:ISSN
348:PMID
330:ISSN
291:PMID
273:ISSN
193:and
2083:MuV
2052:CBV
2027:HEV
2015:HDV
2003:HCV
1991:HAV
1984:CBV
1965:HBV
1842:MuV
1773:V,
1565:CBV
1534:HSV
1511:Eye
1398:LCV
1384:MeV
1315:HIV
1269:HCV
1214:EBV
1161:HPV
1147:HBV
1069:ICD
1054:ICD
1007:PMC
989:doi
942:doi
901:PMC
885:doi
841:PMC
833:doi
829:174
794:doi
755:doi
751:122
708:doi
661:doi
508:doi
464:PMC
448:doi
400:PMC
384:doi
380:336
376:BMJ
338:PMC
322:doi
281:PMC
265:doi
261:166
2241::
1779::
1740::
1734:,
1657::
1655:IV
1432:RV
1123:–
1076::
1061::
1058:10
1015:.
1005:.
997:.
983:.
979:.
956:.
948:.
938:60
936:.
932:.
909:.
899:.
891:.
881:35
879:.
875:.
863:^
849:.
839:.
827:.
823:.
800:.
790:21
788:.
784:.
761:.
749:.
745:.
722:.
714:.
704:98
702:.
698:.
675:.
667:.
657:24
655:.
651:.
628:.
618:96
616:.
612:.
600:^
572:^
544:^
530:.
522:.
514:.
504:36
502:.
498:.
486:^
472:.
462:.
454:.
444:22
442:.
438:.
422:^
408:.
398:.
390:.
378:.
374:.
360:^
346:.
336:.
328:.
318:77
316:.
312:.
289:.
279:.
271:.
259:.
255:.
133:.
51:,
2125:e
2118:t
2111:v
2034:)
2032:E
2030:(
2022:)
2020:D
2018:(
2010:)
2008:C
2006:(
1998:)
1996:A
1994:(
1972:)
1970:B
1968:(
1921:)
1917:(
1876:/
1831:/
1763:/
1755:D
1753:/
1751:C
1749:/
1747:B
1745:/
1732:V
1673:/
1669:/
1665:/
1626:/
1597:/
1590:/
1346:/
1113:e
1106:t
1099:v
1071:-
1056:-
1046:D
1023:.
991::
985:8
964:.
944::
917:.
887::
857:.
835::
808:.
796::
769:.
757::
730:.
710::
683:.
663::
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594:.
566:.
538:.
510::
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450::
416:.
386::
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324::
297:.
267::
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