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Hilary Finucane

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154:) that allows users to search complex data sets in an effort to identify meaningful relationships. Finucane became interested in the application of complex theoretical mathematics to the real world. She returned to the United States in 2012, where she worked toward a doctorate in applied mathematics at 186:, the Encyclopedia of DNA Elements, with GWAS and other biological information to better understand the cell types relevant to a particular disease. Soon after joining the Broad Institute, Finucane was made Associate Director of Medical and Population Genetics. 162:, with whom she developed statistical methods for understanding the genetic basis of human disease. In particular, Finucane considered how specific parts of the genome relate to activity in different cell types, making use of 598: 247:
Finucane, Hilary K.; Bulik-Sullivan, Brendan; Gusev, Alexander; Trynka, Gosia; Reshef, Yakir; Loh, Po-Ru; Anttila, Verneri; Xu, Han; Zang, Chongzhi; Farh, Kyle; Ripke, Stephan (2015).
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Bulik-Sullivan, Brendan K.; Loh, Po-Ru; Finucane, Hilary K.; Ripke, Stephan; Yang, Jian; Patterson, Nick; Daly, Mark J.; Price, Alkes L.; Neale, Benjamin M. (2015).
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Finucane is married to Yakir Reshef, a computer scientist who works on the immune system. She met him during middle school.
553: 179: 163: 139: 118:. She has said that her family enjoyed music and science. Finucane became interested in policy as a child, and started an 40: 143: 529: 410: 102:
is an American computational biologist who is Co-Director of the Program in Medical and Population Genetics at the
471: 106:. Her group combines genetic data with molecular data to understand the origins and mechanisms of disease. 588: 500: 147: 119: 439: 327: 307: 249:"Partitioning heritability by functional annotation using genome-wide association summary statistics" 198:"LD Score regression distinguishes confounding from polygenicity in genome-wide association studies" 131: 361: 343: 286: 268: 235: 217: 351: 335: 276: 260: 225: 209: 82: 175: 123: 103: 57: 36: 331: 356: 315: 281: 248: 230: 197: 582: 311: 299: 127: 71:
Functional and cross-trait genetic architecture of common diseases and complex traits
126:, where eventually majored in mathematics and spent her spare time taking part in 303: 159: 87: 298:
Reshef, David N.; Reshef, Yakir A.; Finucane, Hilary K.; Grossman, Sharon R.;
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student chapter at her high school. She was an undergraduate student at
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The Fannie and John Hertz Foundation | Empowering Limitless Progress
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Massachusetts Institute of Technology School of Science alumni
501:"Hilary Finucane Receives NIH Award – Women In Math" 81: 63: 53: 28: 21: 411:"Linking datasets together to understand disease" 316:"Detecting Novel Associations in Large Data Sets" 174:Finucane was appointed a Schmidt Fellow at the 8: 530:"Faces of the Foundation: Hilary Finucane" 18: 355: 280: 229: 182:Independence Award to combine data from 150:. She developed an analytical tool (the 387: 624:21st-century American women scientists 158:. She eventually started working with 166:(GWAS) to model these relationships. 156:Massachusetts Institute of Technology 33:Massachusetts Institute of Technology 7: 604:Weizmann Institute of Science alumni 466: 464: 405: 403: 401: 399: 397: 395: 393: 391: 14: 16:American computational biologist 564:from the original on 2020-08-03 511:from the original on 2021-04-16 482:from the original on 2017-06-07 450:from the original on 2020-08-03 421:from the original on 2020-08-18 164:genome-wide association studies 152:maximal information coefficient 146:, completing a dissertation on 619:Women computational biologists 1: 180:National Institutes of Health 140:Weizmann Institute of Science 41:Weizmann Institute of Science 144:theoretical computer science 472:"Relating to Relationships" 640: 134:in 2009 Finucane moved to 93: 46: 614:Computational biologists 609:Scientists from Maryland 130:. After graduating from 110:Early life and education 340:10.1126/science.1205438 302:; Turnbaugh, Peter J.; 594:Harvard College alumni 148:geometric group theory 142:. Here she focused on 308:Mitzenmacher, Michael 190:Selected publications 178:. She was awarded an 138:where she joined the 120:Amnesty International 114:Finucane grew up in 100:Hilary Kiyo Finucane 23:Hilary Kiyo Finucane 332:2011Sci...334.1518R 326:(6062): 1518–1524. 170:Research and career 476:Weizmann Institute 444:www.thecrimson.com 312:Sabeti, Pardis C. 259:(11): 1228–1235. 97: 96: 48:Scientific career 631: 573: 572: 570: 569: 550: 544: 543: 541: 540: 526: 520: 519: 517: 516: 497: 491: 490: 488: 487: 468: 459: 458: 456: 455: 436: 430: 429: 427: 426: 407: 369: 359: 294: 284: 243: 233: 83:Doctoral advisor 77: 19: 639: 638: 634: 633: 632: 630: 629: 628: 579: 578: 577: 576: 567: 565: 552: 551: 547: 538: 536: 528: 527: 523: 514: 512: 499: 498: 494: 485: 483: 470: 469: 462: 453: 451: 438: 437: 433: 424: 422: 415:Broad Institute 409: 408: 389: 384: 376: 304:Lander, Eric S. 297: 265:10.1038/ng.3404 253:Nature Genetics 246: 214:10.1038/ng.3211 202:Nature Genetics 195: 192: 176:Broad Institute 172: 124:Harvard College 112: 104:Broad Institute 75: 58:Broad Institute 39: 37:Harvard College 35: 29:Alma mater 24: 17: 12: 11: 5: 637: 635: 627: 626: 621: 616: 611: 606: 601: 596: 591: 581: 580: 575: 574: 545: 521: 492: 478:. 2012-03-05. 460: 431: 417:. 2019-01-16. 386: 385: 383: 380: 375: 372: 371: 370: 314:(2011-12-16). 300:McVean, Gilean 295: 244: 208:(3): 291–295. 191: 188: 171: 168: 111: 108: 95: 94: 91: 90: 85: 79: 78: 67: 61: 60: 55: 51: 50: 44: 43: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 636: 625: 622: 620: 617: 615: 612: 610: 607: 605: 602: 600: 597: 595: 592: 590: 589:Living people 587: 586: 584: 563: 559: 555: 549: 546: 535: 531: 525: 522: 510: 506: 502: 496: 493: 481: 477: 473: 467: 465: 461: 449: 445: 441: 435: 432: 420: 416: 412: 406: 404: 402: 400: 398: 396: 394: 392: 388: 381: 379: 374:Personal life 373: 367: 363: 358: 353: 349: 345: 341: 337: 333: 329: 325: 321: 317: 313: 309: 305: 301: 296: 292: 288: 283: 278: 274: 270: 266: 262: 258: 254: 250: 245: 241: 237: 232: 227: 223: 219: 215: 211: 207: 203: 199: 194: 193: 189: 187: 185: 181: 177: 169: 167: 165: 161: 157: 153: 149: 145: 141: 137: 133: 129: 128:chamber music 125: 121: 117: 109: 107: 105: 101: 92: 89: 86: 84: 80: 73: 72: 68: 66: 62: 59: 56: 52: 49: 45: 42: 38: 34: 31: 27: 20: 566:. Retrieved 557: 548: 537:. Retrieved 533: 524: 513:. Retrieved 505:math.mit.edu 504: 495: 484:. Retrieved 475: 452:. Retrieved 443: 434: 423:. Retrieved 414: 377: 323: 319: 256: 252: 205: 201: 173: 113: 99: 98: 69: 54:Institutions 47: 160:Alkes Price 88:Alkes Price 583:Categories 568:2020-08-16 539:2020-08-16 515:2020-08-16 486:2020-08-16 454:2020-08-16 425:2020-08-16 382:References 348:0036-8075 273:1546-1718 222:1546-1718 562:Archived 558:MIT News 509:Archived 480:Archived 448:Archived 419:Archived 366:22174245 291:26414678 240:25642630 116:Maryland 357:3325791 328:Bibcode 320:Science 282:4626285 231:4495769 132:Harvard 364:  354:  346:  289:  279:  271:  238:  228:  220:  184:ENCODE 136:Israel 76:(2017) 74:  65:Thesis 362:PMID 344:ISSN 287:PMID 269:ISSN 236:PMID 218:ISSN 352:PMC 336:doi 324:334 277:PMC 261:doi 226:PMC 210:doi 585:: 560:. 556:. 532:. 507:. 503:. 474:. 463:^ 446:. 442:. 413:. 390:^ 360:. 350:. 342:. 334:. 322:. 318:. 310:; 306:; 285:. 275:. 267:. 257:47 255:. 251:. 234:. 224:. 216:. 206:47 204:. 200:. 571:. 542:. 518:. 489:. 457:. 428:. 368:. 338:: 330:: 293:. 263:: 242:. 212::

Index

Massachusetts Institute of Technology
Harvard College
Weizmann Institute of Science
Broad Institute
Thesis
Functional and cross-trait genetic architecture of common diseases and complex traits
Doctoral advisor
Alkes Price
Broad Institute
Maryland
Amnesty International
Harvard College
chamber music
Harvard
Israel
Weizmann Institute of Science
theoretical computer science
geometric group theory
maximal information coefficient
Massachusetts Institute of Technology
Alkes Price
genome-wide association studies
Broad Institute
National Institutes of Health
ENCODE
"LD Score regression distinguishes confounding from polygenicity in genome-wide association studies"
doi
10.1038/ng.3211
ISSN
1546-1718

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