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Janet Gilsdorf

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from 1989 to 2012 and Co-Director of the Center for Molecular and Clinical Epidemiology of Infectious Diseases at the School of Public Health at the University of Michigan from 2000 – 2015. In addition to her scientific publications, she is also the author of two novels, one memoir, one non-fiction
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type b (Hib) in children attending child day care. They showed that healthy children attending a day care center in which a child had experienced a serious Hib infection often carried that bacterium in their noses and/or throats without developing serious disease. Gilsdorf and her coauthors also
26:. Her research has focused on the pathogenic, molecular, and epidemiologic features of the bacterium Haemophilus influenzae. She served as the Director of the Division of Pediatric Infectious Diseases in the 44: 51:. She trained in pediatrics at Baylor Affiliated Hospitals in Houston, Texas, and at Valley Medical Center in Fresno, California. She completed a pediatric infectious diseases fellowship at the 132:
adhere to human epithelial cells, Gilsdorf and her collaborators showed that the adherence was mediated by surface proteins called pili and described the components of those structures.
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type b vaccines in native Alaskan children, who exhibited a rate of infection ten to fifteen times higher than that reported in studies from the continental United States.   
1683: 1693: 958:"Identification of a gene essential for piliation in Haemophilus influenzae type b with homology to the pilus assembly platform genes of gram-negative bacteria" 1698: 48: 1688: 63:
Gilsdorf’s research focused primarily on increasing our understanding of the epidemiology, molecular genetics, and pathogenicity of the bacterium
1186:"Comparative Profile of Heme Acquisition Genes in Disease-Causing and Colonizing Nontypeable Haemophilus influenzae and Haemophilus haemolyticus" 715:"Prevention and Control of Haemophilus influenzae Type b Disease: Recommendations of the Advisory Committee on Immunization Practices (ACIP)" 268: 239:
Gilsdorf lives in Ann Arbor, Michigan, with her husband Jim. She has two adult sons. She documented her experience with cancer in her memoir
27: 1072:"Genetic diversity of paired middle-ear and pharyngeal nontypeable Haemophilus influenzae isolates from children with acute otitis media" 76: 1184:
Hariadi, Nurul I.; Zhang, Lixin; Patel, Mayuri; Sandstedt, Sara A.; Davis, Gregg S.; Marrs, Carl F.; Gilsdorf, Janet R. (July 2015).
638:"Haemophilus influenzae type b in a day care center: relationship of nasopharyngeal carriage to development of anticapsular antibody" 1070:
Berrens, Zachary J.; Marrs, Carl F.; Pettigrew, Melinda M.; Sandstedt, Sara A.; Patel, Mayuri; Gilsdorf, Janet R. (November 2007).
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strains, suggesting that the genes more prevalent among disease-causing strains represent bacterial factors that may contribute to
1647: 1300:"Prevalence, distribution, and sequence diversity of hmwA among commensal and otitis media non-typeable Haemophilus influenzae" 1298:
Davis, Gregg S.; Patel, May; Hammond, James; Zhang, Lixin; Dawid, Suzanne; Marrs, Carl F.; Gilsdorf, Janet R. (December 2014).
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carriage. These studies led to the recommendation to treat household and day care center contacts with rifampin to eliminate
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strains. This new technique, identifying bexB in clinical isolates, is now used by the Centers for Disease Control to type
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meningitis in children diagnosed at the Alaska Native Health Service Hospital. This observation led to clinical trials of
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Gilsdorf and her colleagues described a molecular typing method that utilized identification of a key capsule gene among
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Infection, Genetics and Evolution: Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
1015:"High genetic diversity of nontypeable Haemophilus influenzae isolates from two children attending a day care center" 292:
Member, Advisory Committee on Immunization Practices (ACIP), Centers for Disease Control and Prevention, 2003 to 2007
1129:"Pharyngeal colonization dynamics of Haemophilus influenzae and Haemophilus haemolyticus in healthy adult carriers" 1241:
Zhang, Lixin; Patel, Mayuri; Xie, Jingping; Davis, Gregg S.; Marrs, Carl F.; Gilsdorf, Janet R. (February 2013).
1455: 1652: 677:"Comparison of rifampin and ampicillin in day care center contacts of Haemophilus influenzae type b disease" 381: 52: 1013:
Lacross, Nathan C.; Marrs, Carl F.; Patel, Mayuri; Sandstedt, Sara A.; Gilsdorf, Janet R. (November 2008).
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Watson, W. J.; Gilsdorf, J. R.; Tucci, M. A.; McCrea, K. W.; Forney, L. J.; Marrs, C. F. (February 1994).
23: 844:"Cloning, expression, and sequence analysis of the Haemophilus influenzae type b strain M43p+ pilin gene" 437: 357: 143:
Gilsdorf and her colleagues demonstrated the high level of genetic diversity among colonizing strains of
1641: 1243:"Urease operon and urease activity in commensal and disease-causing nontypeable Haemophilus influenzae" 599:"Haemophilus influenzae type B disease in a day care center: eradication of carrier state by rifampin" 1127:
Mukundan, Deepa; Ecevit, Zafer; Patel, Mayuri; Marrs, Carl F.; Gilsdorf, Janet R. (October 2007).
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Gilsdorf and her associates described genetic differences between disease-causing and colonizing
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Board of Scientific Counselors, National Institutes of Health Clinical Center, 2007-2011
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Robert P. Kelch MD Research Professor of Pediatrics Chair, University of Michigan (2010)
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Clemans, D. L.; Marrs, C. F.; Patel, M.; Duncan, M.; Gilsdorf, J. R. (February 1998).
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is an American pediatric infectious diseases physician, scientist, and writer at the
1431: 916: 859: 1625: 560:"It's 'north to Alaska' for research on some vaccines by infectious diseases staff" 1601: 973: 802: 1315: 1383: 1529: 1553: 901:"Conserved and nonconserved epitopes among Haemophilus influenzae type b pili" 755: 478: 1507: 1323: 1266: 1209: 1152: 1095: 1038: 981: 924: 867: 810: 763: 692: 653: 614: 575: 536: 486: 1481: 462: 155:
Identification of genetic differences between pathogenic and non-pathogenic
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Distinguished Physician Award, Pediatric Infectious Diseases Society (2012)
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Gilsdorf, J. R.; Marrs, C. F.; McCrea, K. W.; Forney, L. J. (April 1990).
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While a pediatric resident in Fresno California, Gilsdorf worked with Dr.
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Continual Raving: A History of Meningitis and the People who Conquered It
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Continual Raving: A History of Meningitis and the People who Conquered It
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Granoff, D. M.; Gilsdorf, J.; Gessert, C. E.; Lowe, L. (January 1980).
409:"Janet Gilsdorf, M.D. | Faculty Profiles | U-M School of Public Health" 312:
Board of Directors, Cancer Support Community of Ann Arbor, 2022-present
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Board of Directors, Infectious Diseases Society of America, 2005-2008
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Genetic technique to distinguish encapsulated from non-encapsulated
787:"Comparative analysis of Haemophilus influenzae hifA (pilin) genes" 333: 297:
President, the Pediatric Infectious Diseases Society, 2015 to 2017
1663: 1356:"Meningitis Lab Manual: PCR Detection and Characterization | CDC" 108:
demonstrated the ability of the antibiotic rifampin to decrease
1482:"The Pediatric Infectious Diseases Society Annual Awards, 2012" 740:"Adherence of Haemophilus influenzae to human epithelial cells" 597:
Granoff, D. M.; Gilsdorf, J.; Gessert, C.; Basden, M. (1979).
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Alumni Achievement Award, North Dakota State University (2008)
463:"Changing Epidemiology of Haemophilus influenzae in Children" 1626:
Inside/Outside: A Physician’s Journey with Breast Cancer
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Sarah Goddard Power Award, University of Michigan (2004)
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Inside/Outside: A Physician’s Journey with Breast Cancer
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Inside/Outside: A Physician’s Journey with Breast Cancer
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in Bethel, Alaska, Gilsdorf documented the high rate of
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Gessert, C.; Granoff, D. M.; Gilsdorf, J. (July 1980).
1578:"Former CC Board Members | Clinical Center Home Page" 899:
Gilsdorf, J. R.; McCrea, K.; Forney, L. (July 1990).
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Journal of the Pediatric Infectious Diseases Society
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and received her Doctor of Medicine degree from the
280:, University of Nebraska College of Medicine (2015) 116:carriage and thus decrease the risk of infection. 461:Butler, David F.; Myers, Angela L. (March 2018). 31:book, and a number of medically-oriented essays. 151:strain dynamics during pharyngeal colonization. 71:Bacterial meningitis in Native Alaskan children 513:"Bacterial meningitis in southwestern Alaska" 55:, under the mentorship of Patricia Ferrieri. 45:University of North Dakota School of Medicine 8: 744:Scandinavian Journal of Infectious Diseases 467:Infectious Disease Clinics of North America 49:University of Nebraska College of Medicine 1497: 1331: 1274: 1217: 1160: 1103: 1046: 989: 932: 875: 818: 1572: 1570: 1378: 1376: 267:League of Research Excellence inductee, 403: 401: 328: 326: 322: 1684:American infectious disease physicians 738:Gilsdorf, J. R.; Ferrieri, P. (1984). 432: 430: 428: 147:which led to their description of the 1602:"OUR TEAM – CANCER SUPPORT COMMUNITY" 1460:University of Michigan Medical School 269:University of Michigan Medical School 7: 1694:North Dakota State University alumni 506: 504: 28:University of Michigan Health System 1480:Downes, Kevin J. (September 2012). 511:Gilsdorf, J. R. (1 November 1977). 1555:Dr. Janet Gilsdorf, PIDS President 1384:"The University of Michigan Press" 529:10.1093/oxfordjournals.aje.a112480 438:"Memoir | Faculty History Project" 358:"Memoir | Faculty History Project" 77:Yukon-Kuskokwim Health Corporation 14: 1699:University of North Dakota alumni 278:Doctor of Science Honorary Degree 1247:Journal of Clinical Microbiology 1190:Journal of Clinical Microbiology 1133:Journal of Clinical Microbiology 1076:Journal of Clinical Microbiology 1019:Journal of Clinical Microbiology 517:American Journal of Epidemiology 1456:"League of Research Excellence" 917:10.1128/iai.58.7.2252-2257.1990 860:10.1128/iai.58.4.1065-1072.1990 1689:University of Michigan faculty 95:in children attending day care 1: 974:10.1128/iai.62.2.468-475.1994 803:10.1128/IAI.66.2.656-663.1998 41:North Dakota State University 16:American scientist and writer 1631:University of Michigan Press 1388:University of Michigan Press 1316:10.1016/j.meegid.2014.09.035 442:faculty-history.dc.umich.edu 362:faculty-history.dc.umich.edu 170:pathogenicity and disease. 103:, to investigate spread of 1715: 1530:"IAC EXPRESS - Issue #568" 756:10.3109/00365548409070400 558:Cotton, P. (1990-05-16). 479:10.1016/j.idc.2017.10.005 128:After demonstrating that 124:to human epithelial cells 382:"My Bibliography - NCBI" 39:Janet Gilsdorf attended 35:Early life and education 1653:Oxford University Press 1432:"Past Award Recipients" 255:faculty inductee (1999) 53:University of Minnesota 1582:clinicalcenter.nih.gov 962:Infection and Immunity 905:Infection and Immunity 848:Infection and Immunity 791:Infection and Immunity 105:Haemophilus influenzae 65:Haemophilus influenzae 24:University of Michigan 1642:Kensington Publishing 136:Genetic diversity of 75:While working at the 1499:10.1093/jpids/pis074 1259:10.1128/JCM.03145-12 1202:10.1128/JCM.00345-15 1145:10.1128/JCM.00492-07 1088:10.1128/JCM.00964-07 1031:10.1128/JCM.00940-08 386:www.ncbi.nlm.nih.gov 287:Professional service 1412:Alpha Omega Alpha 1139:(10): 3207–3217. 1082:(11): 3764–3767. 1025:(11): 3817–3821. 253:Alpha Omega Alpha 1706: 1612: 1611: 1609: 1608: 1598: 1592: 1591: 1589: 1588: 1574: 1565: 1564: 1563: 1562: 1550: 1544: 1543: 1541: 1540: 1534:www.immunize.org 1526: 1520: 1519: 1501: 1477: 1471: 1470: 1468: 1467: 1452: 1446: 1445: 1443: 1442: 1428: 1422: 1421: 1419: 1418: 1404: 1398: 1397: 1395: 1394: 1380: 1371: 1370: 1368: 1367: 1352: 1346: 1345: 1335: 1295: 1289: 1288: 1278: 1238: 1232: 1231: 1221: 1196:(7): 2132–2137. 1181: 1175: 1174: 1164: 1124: 1118: 1117: 1107: 1067: 1061: 1060: 1050: 1010: 1004: 1003: 993: 953: 947: 946: 936: 911:(7): 2252–2257. 896: 890: 889: 879: 854:(4): 1065–1072. 839: 833: 832: 822: 782: 776: 775: 735: 729: 728: 726: 725: 711: 705: 704: 672: 666: 665: 633: 627: 626: 594: 588: 587: 555: 549: 548: 508: 499: 498: 458: 452: 451: 449: 448: 434: 423: 422: 420: 419: 405: 396: 395: 393: 392: 378: 372: 371: 369: 368: 354: 348: 347: 345: 344: 330: 91:Colonization of 1714: 1713: 1709: 1708: 1707: 1705: 1704: 1703: 1669: 1668: 1621: 1616: 1615: 1606: 1604: 1600: 1599: 1595: 1586: 1584: 1576: 1575: 1568: 1560: 1558: 1552: 1551: 1547: 1538: 1536: 1528: 1527: 1523: 1479: 1478: 1474: 1465: 1463: 1454: 1453: 1449: 1440: 1438: 1436:NDSU Foundation 1430: 1429: 1425: 1416: 1414: 1406: 1405: 1401: 1392: 1390: 1382: 1381: 1374: 1365: 1363: 1354: 1353: 1349: 1297: 1296: 1292: 1240: 1239: 1235: 1183: 1182: 1178: 1126: 1125: 1121: 1069: 1068: 1064: 1012: 1011: 1007: 955: 954: 950: 898: 897: 893: 841: 840: 836: 784: 783: 779: 737: 736: 732: 723: 721: 713: 712: 708: 674: 673: 669: 635: 634: 630: 596: 595: 591: 557: 556: 552: 510: 509: 502: 460: 459: 455: 446: 444: 436: 435: 426: 417: 415: 407: 406: 399: 390: 388: 380: 379: 375: 366: 364: 356: 355: 351: 342: 340: 332: 331: 324: 319: 289: 249: 237: 218: 199: 194: 179: 160: 141: 126: 97: 73: 61: 37: 17: 12: 11: 5: 1712: 1710: 1702: 1701: 1696: 1691: 1686: 1681: 1671: 1670: 1667: 1666: 1664:Beaufort Books 1655: 1644: 1633: 1620: 1619:External links 1617: 1614: 1613: 1593: 1566: 1545: 1521: 1492:(3): 171–178. 1472: 1447: 1423: 1399: 1372: 1347: 1290: 1253:(2): 653–655. 1233: 1176: 1119: 1062: 1005: 968:(2): 468–475. 948: 891: 834: 797:(2): 656–663. 777: 750:(3): 271–278. 730: 706: 667: 628: 609:(3): 397–401. 589: 550: 523:(5): 388–391. 500: 473:(1): 119–128. 453: 424: 397: 373: 349: 321: 320: 318: 315: 314: 313: 309: 308: 304: 303: 299: 298: 294: 293: 288: 285: 284: 283: 275: 272: 265: 262: 259: 256: 248: 245: 236: 233: 232: 231: 225: 217: 214: 213: 212: 206: 198: 195: 193: 192:Literary works 190: 187:H. influenzae. 178: 172: 159: 153: 145:H. influenzae, 140: 134: 125: 118: 101:Dan M. Granoff 96: 89: 72: 69: 60: 57: 36: 33: 20:Janet Gilsdorf 15: 13: 10: 9: 6: 4: 3: 2: 1711: 1700: 1697: 1695: 1692: 1690: 1687: 1685: 1682: 1680: 1679:Living people 1677: 1676: 1674: 1665: 1661: 1660: 1656: 1654: 1650: 1649: 1645: 1643: 1639: 1638: 1634: 1632: 1628: 1627: 1623: 1622: 1618: 1603: 1597: 1594: 1583: 1579: 1573: 1571: 1567: 1557: 1556: 1549: 1546: 1535: 1531: 1525: 1522: 1517: 1513: 1509: 1505: 1500: 1495: 1491: 1487: 1483: 1476: 1473: 1461: 1457: 1451: 1448: 1437: 1433: 1427: 1424: 1413: 1409: 1408:"Summer 2022" 1403: 1400: 1389: 1385: 1379: 1377: 1373: 1361: 1357: 1351: 1348: 1343: 1339: 1334: 1329: 1325: 1321: 1317: 1313: 1309: 1305: 1301: 1294: 1291: 1286: 1282: 1277: 1272: 1268: 1264: 1260: 1256: 1252: 1248: 1244: 1237: 1234: 1229: 1225: 1220: 1215: 1211: 1207: 1203: 1199: 1195: 1191: 1187: 1180: 1177: 1172: 1168: 1163: 1158: 1154: 1150: 1146: 1142: 1138: 1134: 1130: 1123: 1120: 1115: 1111: 1106: 1101: 1097: 1093: 1089: 1085: 1081: 1077: 1073: 1066: 1063: 1058: 1054: 1049: 1044: 1040: 1036: 1032: 1028: 1024: 1020: 1016: 1009: 1006: 1001: 997: 992: 987: 983: 979: 975: 971: 967: 963: 959: 952: 949: 944: 940: 935: 930: 926: 922: 918: 914: 910: 906: 902: 895: 892: 887: 883: 878: 873: 869: 865: 861: 857: 853: 849: 845: 838: 835: 830: 826: 821: 816: 812: 808: 804: 800: 796: 792: 788: 781: 778: 773: 769: 765: 761: 757: 753: 749: 745: 741: 734: 731: 720: 716: 710: 707: 702: 698: 694: 690: 686: 682: 678: 671: 668: 663: 659: 655: 651: 647: 643: 639: 632: 629: 624: 620: 616: 612: 608: 604: 600: 593: 590: 585: 581: 577: 573: 569: 565: 561: 554: 551: 546: 542: 538: 534: 530: 526: 522: 518: 514: 507: 505: 501: 496: 492: 488: 484: 480: 476: 472: 468: 464: 457: 454: 443: 439: 433: 431: 429: 425: 414: 413:sph.umich.edu 410: 404: 402: 398: 387: 383: 377: 374: 363: 359: 353: 350: 339: 335: 329: 327: 323: 316: 311: 310: 306: 305: 301: 300: 296: 295: 291: 290: 286: 282: 279: 276: 273: 270: 266: 263: 260: 257: 254: 251: 250: 246: 244: 242: 235:Personal life 234: 229: 226: 223: 220: 219: 215: 210: 207: 204: 201: 200: 196: 191: 189: 188: 184: 183:H. influenzae 177: 176:H. influenzae 173: 171: 169: 168:H. influenzae 165: 164:H. influenzae 158: 157:H. influenzae 154: 152: 150: 149:H. influenzae 146: 139: 138:H. influenzae 135: 133: 131: 130:H. influenzae 123: 122:H. influenzae 120:Adherence of 119: 117: 115: 114:H. influenzae 111: 110:H. influenzae 106: 102: 94: 93:H. influenzae 90: 88: 86: 85:H. influenzae 82: 81:H. influenzae 78: 70: 68: 66: 58: 56: 54: 50: 46: 42: 34: 32: 29: 25: 21: 1657: 1646: 1635: 1624: 1605:. 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Index

University of Michigan
University of Michigan Health System
North Dakota State University
University of North Dakota School of Medicine
University of Nebraska College of Medicine
University of Minnesota
Yukon-Kuskokwim Health Corporation
Dan M. Granoff
Alpha Omega Alpha
University of Michigan Medical School
Doctor of Science Honorary Degree



"PubMed"
"Memoir | Faculty History Project"
"My Bibliography - NCBI"


"Janet Gilsdorf, M.D. | Faculty Profiles | U-M School of Public Health"



"Memoir | Faculty History Project"
"Changing Epidemiology of Haemophilus influenzae in Children"
doi
10.1016/j.idc.2017.10.005
ISSN
1557-9824
PMID

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