422:, including the Committee on Validation of Toxicogenomic Technologies: A Focus on Chemical Classification Strategies, the Panel on Collecting, Storing, Accessing, and Protecting Biological Specimens and Biodata Social Science Surveys, and the Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials. He is currently a member of scientific advisory boards at
456:
392:(NHLBI), will add genetic, genomic, and epigenetic data to a collection of clinical biological samples developed by the NHLBI's Lung Tissue Research Consortium. The consortium aims to use genomic technologies and advanced data-analysis tools on available patient lung-tissue samples to gain new insights into
727:
Fantom, Consortium; Suzuki, H; Forrest, A. R.; Van
Nimwegen, E; Daub, C. O.; Balwierz, P. J.; Irvine, K. M.; Lassmann, T; Ravasi, T; Hasegawa, Y; De Hoon, M. J.; Katayama, S; Schroder, K; Carninci, P; Tomaru, Y; Kanamori-Katayama, M; Kubosaki, A; Akalin, A; Ando, Y; Arner, E; Asada, M; Asahara, H;
407:. He was also awarded a four-million-dollar fellowship bestowed by Australia's National Health and Medical Research Council to study chemotherapy resistant ovarian cancers in collaboration with colleagues at the University of Queensland's Institute for Molecular Bioscience.
557:
561:
434:'s Roadmap Epigenomics Project. Quackenbush is also a member of the scientific advisory boards of a number of biotech and precision medicine companies, including Caris Life Sciences, SynapDx, Perthera, and NABsys.
659:
Okazaki, Y.; Furuno, M.; Kasukawa, T.; Adachi, J.; Bono, H.; Kondo, S.; Nikaido, I.; Osato, N.; Saito, R.; Suzuki, H.; Yamanaka, I.; Kiyosawa, H.; Yagi, K.; Tomaru, Y.; Hasegawa, Y.; Nogami, A.; Schönbach, C.;
361:-based approaches to understanding and modeling the biological networks that underlie disease. This has led him and his colleagues to make fundamental discoveries about the role that variation in
437:
In 2011, Quackenbush, along with partner Mick
Correll, founded Genospace, a software company focused on developing tools to enable precision genomic medicine. As of 2014, Quackenbush was the
1216:
1211:
1236:
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444:
In
January, 2017, Genospace was acquired by Hospital Corporation of America (HCA) and merged with HCA's Sarah Cannon cancer institute as a wholly owned subsidiary.
232:, as well as the director of its Center for Cancer Computational Biology (CCCB). Quackenbush also holds an appointment as a professor of computational biology and
385:
789:; Aturaliya, R. N.; Bailey, T. L.; Bansal, M; Baxter, L; Beisel, K. W.; Bersano, T; et al. (2005). "The transcriptional landscape of the mammalian genome".
288:
in physics, Quackenbush was awarded a
Special Emphasis Research Career Award from the National Center for Human Genome Research (the predecessor of the
323:. Using a combination of laboratory and computational approaches, Quackenbush and his group developed analytical methods based on the integration of
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289:
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support to the research community through a collaborative consulting model, and which also performs and analyzes large-scale second-generation
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338:. Four years later, he launched the DFCI's Center for Cancer Computational Biology, which he directs and which provides broad-based
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381:
785:; Batalov, S; Forrest, A. R.; Zavolan, M; Davis, M. J.; Wilming, L. G.; Aidinis, V; Allen, J. E.; Ambesi-Impiombato, A;
730:"The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line"
253:
728:
Bailey, T; Bajic, V. B.; Bauer, D; Beckhouse, A. G.; Bertin, N; Björkegren, J; Brombacher, F; et al. (2009).
170:
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of
Genospace. In the summer of 2013, Quackenbush was honored as a White House Open Science Champion of Change.
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373:
257:
124:
940:
575:
471:
781:; Frith, M. C.; Maeda, N; Oyama, R; Ravasi, T; Lenhard, B; Wells, C; Kodzius, R; Shimokawa, K; Bajic, V. B.;
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199:
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668:; Schriml, L. M.; Kanapin, A.; Matsuda, H.; Batalov, S.; Beisel, K. W.; Blake, J. A.; et al. (2002).
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40:
920:"Dana-Farber, Quackenbush Launch Analysis Consultancy Center | Genome Technology | Informatics"
419:
343:
285:
218:
83:
1022:"COMMITTEE ON VALIDATION OF TOXICOGENOMIC TECHNOLOGIES: A FOCUS ON CHEMICAL CLASSIFICATION STRATEGIES"
410:
Quackenbush currently serves on the editorial boards of five major journals and is editor-in-chief at
1107:
Conducting
Biosocial Surveys: Collecting, Storing, Accessing, and Protecting Biospecimens and Biodata
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670:"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs"
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Gauge field theory in two space-time dimensions: Anomalies and applications to string models
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Gauge field theory in two space-time dimensions: Anomalies and applications to string models
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403:(Imagine Publishing, U.S.), which outlines the history, science, and implications of the
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268:, where he earned a bachelor's degree in physics. He went on to earn a doctorate in
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319:, where his focus began to shift to post-genomic applications, with an emphasis on
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138:
368:
In 2010, Quackenbush and his colleagues at CCCB, together with investigators at
885:
576:"Computational Biology and Functional Genomics Laboratory - John Quackenbush"
388:
to launch the Lung
Genomics Research Consortium. This project, funded by the
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206:
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818:
763:
713:
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380:'s Section for Computational Biomedicine and the Pulmonary Center, and the
376:'s Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease,
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developing new laboratory and computational strategies for sequencing the
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327:
across domains to derive biological meaning from high-dimensional data.
704:
496:
Bioinformatics: A Practical Guide to the
Analysis of Genes and Proteins
225:
962:"John Quackenbush, Lung Genomics Research Consortium Investigator Bio"
1153:
Micheel, Christine M; Nass, Sharly J; Omenn, Gilbert S, eds. (2012).
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1064:"APPENDIX A - WORKSHOP PLANNING COMMITTEE, BIOGRAPHICAL INFORMATION"
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384:'s Genomics Core Facility received an $ 11 million grant under the
330:
In 2005, Quackenbush was appointed to his current positions at the
1194:
Celebrating “Open
Science” Champions of Change at the White House
353:
Quackenbush's current research focuses on the analysis of human
324:
503:
Microarray Gene
Expression Data Analysis: A Beginner's Guide
396:
and thus develop more effective, personalized treatments.
594:"John Quackenbush, Harvard School of Public Health Bio"
664:; Baldarelli, R.; Hill, D. P.; Bult, C.; Hume, D. A.;
980:"Lung Genomics Research Consortium Launches Website"
292:), and subsequently spent the next two years at the
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149:
131:
108:
75:
51:
35:
28:
884:
852:
264:, graduating in 1979, after which he attended the
1217:Harvard T.H. Chan School of Public Health faculty
620:"Bioinformatics for next generation sequencing"
560:. Dana Farber Cancer Institute. Archived from
430:, The Hope Funds for Cancer Research, and the
386:American Recovery and Reinvestment Act of 2009
489:The Human Genome: Book of Essential Knowledge
414:. He has served on several committees at the
401:The Human Genome: Book of Essential Knowledge
372:'s Center for Genes, Environment and Health,
8:
1212:University of California, Los Angeles alumni
1237:Members of the National Academy of Medicine
864:. Cambridge Healthtech Institute. p. 4
558:"Researcher Profile, John Quackenbush, PhD"
311:In 1997, Quackenbush joined the faculty of
25:
1222:California Institute of Technology alumni
753:
703:
693:
635:
365:plays in defining biological phenotypes.
1068:Validation of Toxicogenomic Technologies
1026:Validation of Toxicogenomic Technologies
941:"Integrating Clinical and Genomics Data"
290:National Human Genome Research Institute
777:Carninci, P; Kasukawa, T; Katayama, S;
515:
428:Lovelace Respiratory Research Institute
390:National Heart Lung and Blood Institute
893:University of California, Los Angeles
846:
844:
842:
840:
838:
836:
424:St. Jude Children's Research Hospital
274:University of California, Los Angeles
65:University of California, Los Angeles
7:
596:. Harvard University. Archived from
578:. Harvard University. Archived from
964:. lung-genomics.org. Archived from
300:, followed by another two years at
230:Dana–Farber Cancer Institute (DFCI)
1110:. National Academies Press. 2010.
1070:. National Academies Press. 2007.
1028:. National Academies Press. 2007.
313:The Institute for Genomic Research
266:California Institute of Technology
121:Institute for Molecular Bioscience
56:California Institute of Technology
14:
1156:Evolution of Translational Omics
491:(Imagine Publishing, U.S., 2011)
454:
918:Dublin, Matthew (31 May 2009).
538:John Quackenbush's publications
399:In 2011, Quackenbush published
336:Harvard School of Public Health
242:Harvard School of Public Health
982:. National Jewish Organization
1:
637:10.1093/bioinformatics/btp037
432:National Institute for Health
382:University of Colorado Denver
284:After working two years as a
1159:. National Academies Press.
332:Dana–Farber Cancer Institute
296:working on physical maps of
117:Dana–Farber Cancer Institute
1253:
1227:American bioinformaticians
1001:"Industry-News.net - Home"
883:Quackenbush, John (1990).
498:(Wiley Interscience, 2004)
254:Mountain Top, Pennsylvania
18:
161:
101:
16:American bioinformatician
544:bibliographic database.
525:publications indexed by
374:University of Pittsburgh
258:Bishop Hoban High School
248:Education and early life
125:University of Queensland
19:For the politician, see
1003:. Biotechnologynews.net
811:10.1126/science.1112014
546:(subscription required)
505:(Wiley-Blackwell, 2003)
439:chief executive officer
256:, Quackenbush attended
200:computational biologist
862:2014 Bio-IT World Expo
370:National Jewish Health
41:Kingston, Pennsylvania
420:Institute of Medicine
344:computational biology
236:in the Department of
219:computational biology
185:/john-quackenbush-phd
84:computational biology
405:Human Genome Project
854:"2014-BIT-Brochure"
803:2005Sci...309.1559F
695:10.1038/nature01266
686:2002Natur.420..563O
321:microarray analysis
317:Rockville, Maryland
302:Stanford University
298:human chromosome 11
286:postdoctoral fellow
280:Career and research
270:theoretical physics
221:and a professor of
96:functional genomics
88:microarray analysis
21:John A. Quackenbush
416:National Academies
113:Harvard University
1174:978-0-309-22418-5
1125:978-0-309-15706-3
1085:978-0-309-10413-5
1043:978-0-309-10413-5
797:(5740): 1559–63.
680:(6915): 563–573.
394:pulmonary disease
378:Boston University
193:
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103:Scientific career
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151:Doctoral advisor
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734:Nature Genetics
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666:Quackenbush, J.
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540:indexed by the
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363:gene expression
359:systems biology
282:
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198:is an American
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156:Terry Tomboulis
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63:
52:Alma mater
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24:
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1116:10.17226/12942
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1076:10.17226/11804
1055:
1042:
1034:10.17226/11804
1013:
992:
971:
968:on 2012-03-19.
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943:. Bio-IT World
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910:
875:
851:Staff (2014).
832:
783:Brenner, S. E.
769:
746:10.1038/ng.375
719:
651:
624:Bioinformatics
616:Quackenbush, J
603:
600:on 2011-02-25.
585:
582:on 2015-01-25.
567:
564:on 2015-04-07.
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527:Google Scholar
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348:DNA sequencing
340:bioinformatics
294:Salk Institute
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181:/member-detail
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956:
945:. Retrieved
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866:. Retrieved
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662:Gojobori, T.
654:
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570:
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469:
468:profile for
465:
448:Publications
443:
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411:
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398:
367:
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329:
310:
306:human genome
283:
262:Wilkes Barre
252:A native of
251:
195:
194:
137:
109:Institutions
102:
922:. GenomeWeb
787:Apweiler, R
705:10161/11223
1206:Categories
1180:2013-04-04
1139:2013-04-04
1091:2013-04-04
1049:2013-04-04
1007:2012-05-07
986:2013-04-04
947:2012-05-07
926:2012-05-07
630:(4): 429.
612:Bateman, A
510:References
501:Coauthor,
315:(TIGR) in
209:. He is a
891:(Ph.D.).
276:in 1990.
272:from the
211:professor
207:scientist
1134:21210553
905:ProQuest
901:22713736
819:16141072
779:Gough, J
764:19377474
714:12466851
646:19202193
618:(2009).
487:Author,
418:and the
412:Genomics
334:and the
179:/insider
175:.harvard
92:genomics
868:15 June
827:8712839
799:Bibcode
791:Science
755:6711855
682:Bibcode
464:has an
462:Scholia
240:at the
228:at the
226:biology
183:/member
166:Website
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674:Nature
644:
542:Scopus
466:author
426:, the
357:using
355:cancer
223:cancer
204:genome
173:.dfhcc
144:(1990)
142:
133:Thesis
858:(PDF)
823:S2CID
482:Books
69:Ph.D.
1169:ISBN
1130:PMID
1120:ISBN
1080:ISBN
1038:ISBN
897:OCLC
870:2016
815:PMID
760:PMID
710:PMID
642:PMID
342:and
325:data
217:and
202:and
177:.edu
60:B.S.
36:Born
1161:doi
1112:doi
1072:doi
1030:doi
807:doi
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750:PMC
742:doi
700:hdl
690:doi
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632:doi
350:.
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213:of
171:www
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