33:
483:
455:
There are many investigations about the use of peroxidase in many manufacturing processes like adhesives, computer chips, car parts, and linings of drums and cans. Other studies have shown that peroxidases may be used successfully to polymerize anilines and phenols in organic solvent matrices.
197:
452:. Thus phenols are oxidized to phenoxy radicals, which participate in reactions where polymers and oligomers are produced that are less toxic than phenols. It also can be used to convert toxic materials into less harmful substances.
637:
Karthikeyan M, Jayakumar V, Radhika K, Bhaskaran R, Velazhahan R, Alice D (December 2005). "Induction of resistance in host against the infection of leaf blight pathogen (Alternaria palandui) in onion (Allium cepa var aggregatum)".
664:
Prakasha, A, Umesha, S. Biochemical and
Molecular Variations of Guaiacol Peroxidase and Total Phenols in Bacterial Wilt Pathogenesis of Solanum melongena. Biochemistry & Analytical Biochemistry, 5,292,
674:
Tuhela, L., G. K. Sims, and O. Tuovinen. 1989. Polymerization of substituted anilines, phenols, and heterocyclic compounds by peroxidase in organic solvents. Columbus, Ohio: The Ohio State
University. 58
414:
While the exact mechanisms have yet to be determined, peroxidases are known to play a part in increasing a plant's defenses against pathogens. Many members of the
Solanaceae, notably
94:
716:
943:
287:
308:
61:
1099:
580:"Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease"
292:
1084:
256:
can use a variety of organic compounds as electron donors and acceptors. Horseradish peroxidase has an accessible
1200:
1187:
1174:
1161:
1148:
1135:
1122:
872:
742:
709:
1094:
1048:
991:
855:
733:
328:
208:
58:
68:
which play a role in various biological processes. They are named after the fact that they commonly break up
996:
860:
770:
506:
464:
264:
227:
830:
780:
449:
432:
399:. This group is able to form reactive halogen species and, as a result, natural organohalogen substances.
355:
319:
253:
1227:
1017:
936:
775:
760:
1089:
702:
591:
496:
468:
336:
1053:
501:
1222:
986:
845:
537:
647:
619:
422:
363:
212:
38:
1032:
1027:
1001:
929:
755:
609:
599:
521:
1079:
1063:
976:
890:
885:
840:
835:
750:
531:
526:
448:, which are important pollutants, can be removed by enzyme-catalyzed polymerization using
341:
283:
267:, the compounds that donate electrons are very specific, due to a very narrow active site.
192:{\displaystyle {\ce {ROOR'+{\overset {electron \atop donor}{2e^{-}}}+2H+->{ROH}+R'OH}}}
694:
595:
1117:
1058:
725:
614:
579:
511:
488:
396:
303:
238:
220:
1216:
1022:
981:
876:
383:
323:
216:
436:: the gene expression for this enzyme commences within minutes of bacterial attack.
430:
and the enzyme guaiacol peroxidase as a defense against bacterial parasites such as
971:
389:
32:
688:
557:
1195:
1130:
966:
793:
516:
371:
359:
257:
245:
584:
Proceedings of the
National Academy of Sciences of the United States of America
482:
850:
478:
444:
Peroxidase can be used for treatment of industrial waste waters. For example,
403:
1169:
1143:
604:
460:
651:
623:
17:
765:
427:
415:
379:
297:
234:
77:
69:
445:
358:
family consists of 8 known human isoforms. Glutathione peroxidases use
42:
1182:
952:
65:
160:
1156:
910:
905:
900:
895:
392:, when bound to heme, has been shown to have peroxidase activity.
231:
31:
823:
818:
813:
808:
803:
798:
788:
375:
367:
224:
925:
698:
402:
A majority of peroxidase protein sequences can be found in the
426:(the habanero/Scotch bonnet varieties of chili peppers) use
921:
386:
in humans with cysteine-containing homologues in rodents.
260:, and many compounds can reach the site of the reaction.
88:
Peroxidases typically catalyze a reaction of the form:
97:
72:, and should not be confused with other enzymes that
276:
Protein families that serve as peroxidases include:
1108:
1072:
1041:
1010:
959:
871:
741:
248:is very dependent on the structure of the enzyme.
191:
467:is used as a soluble, easily purified model for
640:Indian Journal of Biochemistry & Biophysics
362:as an electron donor and are active with both
937:
710:
8:
944:
930:
922:
717:
703:
695:
215:, but others are more active with organic
613:
603:
263:On the other hand, for an enzyme such as
169:
161:
155:
149:
144:
121:
116:
110:
98:
96:
549:
395:A typical group of peroxidases are the
382:-containing enzymes, whereas Gpx6 is a
366:and organic hydroperoxide substrates.
230:in their active sites, or alternately
207:For many of these enzymes the optimal
7:
578:Atamna H, Boyle K (February 2006).
459:Peroxidases are sometimes used as
128:
25:
288:animal heme-dependent peroxidases
558:"RedOxiBase: Peroxidase Classes"
481:
309:Di-haem cytochrome c peroxidase
1:
333:Alkyl hydroperoxide reductase
223:. Peroxidases can contain a
691:, a database of peroxidases
27:Peroxide-decomposing enzyme
1244:
293:DyP-type peroxidase family
76:peroxide, which are often
36:Glutathione Peroxidase 1 (
1100:Michaelis–Menten kinetics
420:(eggplant/aubergine) and
992:Diffusion-limited enzyme
856:Iodothyronine deiodinase
329:vanadium bromoperoxidase
861:Iodotyrosine deiodinase
771:Cytochrome c peroxidase
605:10.1073/pnas.0600134103
507:Cytochrome c peroxidase
465:Cytochrome c peroxidase
265:cytochrome c peroxidase
64:) are a large group of
831:Horseradish peroxidase
781:Glutathione peroxidase
450:horseradish peroxidase
433:Ralstonia solanacearum
378:have been shown to be
356:glutathione peroxidase
320:glutathione peroxidase
254:horseradish peroxidase
193:
47:
1085:Eadie–Hofstee diagram
1018:Allosteric regulation
776:Eosinophil peroxidase
761:Fatty-acid peroxidase
410:Pathogenic resistance
194:
35:
1095:Lineweaver–Burk plot
497:Ascorbate peroxidase
469:cytochrome c oxidase
337:Manganese peroxidase
95:
596:2006PNAS..103.3381A
502:Chloride peroxidase
166:
55:peroxide reductases
1054:Enzyme superfamily
987:Enzyme promiscuity
846:Thyroid peroxidase
538:Thyroid peroxidase
244:The nature of the
203:Optimal substrates
189:
48:
1210:
1209:
919:
918:
423:Capsicum chinense
417:Solanum melongena
364:hydrogen peroxide
213:hydrogen peroxide
187:
180:
172:
167:
164:
148:
136:
135:
134:
131:
120:
102:
16:(Redirected from
1235:
1090:Hanes–Woolf plot
1033:Enzyme activator
1028:Enzyme inhibitor
1002:Enzyme catalysis
946:
939:
932:
923:
756:NADPH peroxidase
719:
712:
705:
696:
676:
672:
666:
662:
656:
655:
634:
628:
627:
617:
607:
575:
569:
568:
566:
564:
554:
522:Immunoperoxidase
491:
486:
485:
350:Characterization
286:and the related
198:
196:
195:
190:
188:
185:
184:
178:
173:
170:
168:
165:
162:
156:
154:
153:
146:
137:
132:
129:
127:
126:
125:
118:
111:
106:
100:
45:
21:
1243:
1242:
1238:
1237:
1236:
1234:
1233:
1232:
1213:
1212:
1211:
1206:
1118:Oxidoreductases
1104:
1080:Enzyme kinetics
1068:
1064:List of enzymes
1037:
1006:
977:Catalytic triad
955:
950:
920:
915:
867:
841:Myeloperoxidase
836:Lactoperoxidase
751:NADH peroxidase
737:
726:Oxidoreductases
723:
685:
680:
679:
673:
669:
663:
659:
636:
635:
631:
577:
576:
572:
562:
560:
556:
555:
551:
546:
532:Myeloperoxidase
527:Lactoperoxidase
487:
480:
477:
442:
412:
397:haloperoxidases
352:
342:NADH peroxidase
284:haem peroxidase
274:
221:lipid peroxides
205:
177:
145:
117:
112:
99:
93:
92:
86:
37:
28:
23:
22:
15:
12:
11:
5:
1241:
1239:
1231:
1230:
1225:
1215:
1214:
1208:
1207:
1205:
1204:
1191:
1178:
1165:
1152:
1139:
1126:
1112:
1110:
1106:
1105:
1103:
1102:
1097:
1092:
1087:
1082:
1076:
1074:
1070:
1069:
1067:
1066:
1061:
1056:
1051:
1045:
1043:
1042:Classification
1039:
1038:
1036:
1035:
1030:
1025:
1020:
1014:
1012:
1008:
1007:
1005:
1004:
999:
994:
989:
984:
979:
974:
969:
963:
961:
957:
956:
951:
949:
948:
941:
934:
926:
917:
916:
914:
913:
908:
903:
898:
893:
888:
882:
880:
869:
868:
866:
865:
864:
863:
858:
848:
843:
838:
833:
828:
827:
826:
821:
816:
811:
806:
801:
796:
791:
778:
773:
768:
763:
758:
753:
747:
745:
739:
738:
724:
722:
721:
714:
707:
699:
693:
692:
684:
683:External links
681:
678:
677:
667:
657:
629:
570:
548:
547:
545:
542:
541:
540:
535:
529:
524:
519:
514:
512:Haloperoxidase
509:
504:
499:
493:
492:
489:Biology portal
476:
473:
441:
438:
411:
408:
351:
348:
347:
346:
345:
344:
339:
334:
331:
326:
313:
312:
311:
306:
304:haloperoxidase
300:
295:
290:
273:
272:Classification
270:
269:
268:
261:
246:electron donor
239:selenocysteine
217:hydroperoxides
204:
201:
200:
199:
183:
176:
159:
152:
143:
140:
124:
115:
109:
105:
85:
82:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1240:
1229:
1226:
1224:
1221:
1220:
1218:
1202:
1198:
1197:
1192:
1189:
1185:
1184:
1179:
1176:
1172:
1171:
1166:
1163:
1159:
1158:
1153:
1150:
1146:
1145:
1140:
1137:
1133:
1132:
1127:
1124:
1120:
1119:
1114:
1113:
1111:
1107:
1101:
1098:
1096:
1093:
1091:
1088:
1086:
1083:
1081:
1078:
1077:
1075:
1071:
1065:
1062:
1060:
1059:Enzyme family
1057:
1055:
1052:
1050:
1047:
1046:
1044:
1040:
1034:
1031:
1029:
1026:
1024:
1023:Cooperativity
1021:
1019:
1016:
1015:
1013:
1009:
1003:
1000:
998:
995:
993:
990:
988:
985:
983:
982:Oxyanion hole
980:
978:
975:
973:
970:
968:
965:
964:
962:
958:
954:
947:
942:
940:
935:
933:
928:
927:
924:
912:
909:
907:
904:
902:
899:
897:
894:
892:
889:
887:
884:
883:
881:
878:
877:peroxiredoxin
874:
870:
862:
859:
857:
854:
853:
852:
849:
847:
844:
842:
839:
837:
834:
832:
829:
825:
822:
820:
817:
815:
812:
810:
807:
805:
802:
800:
797:
795:
792:
790:
787:
784:
783:
782:
779:
777:
774:
772:
769:
767:
764:
762:
759:
757:
754:
752:
749:
748:
746:
744:
740:
735:
731:
727:
720:
715:
713:
708:
706:
701:
700:
697:
690:
687:
686:
682:
671:
668:
661:
658:
653:
649:
645:
641:
633:
630:
625:
621:
616:
611:
606:
601:
597:
593:
590:(9): 3381–6.
589:
585:
581:
574:
571:
559:
553:
550:
543:
539:
536:
533:
530:
528:
525:
523:
520:
518:
515:
513:
510:
508:
505:
503:
500:
498:
495:
494:
490:
484:
479:
474:
472:
470:
466:
462:
457:
453:
451:
447:
439:
437:
435:
434:
429:
425:
424:
419:
418:
409:
407:
405:
400:
398:
393:
391:
387:
385:
384:selenoprotein
381:
377:
373:
369:
365:
361:
357:
349:
343:
340:
338:
335:
332:
330:
327:
325:
324:peroxiredoxin
321:
317:
316:
314:
310:
307:
305:
301:
299:
296:
294:
291:
289:
285:
282:
281:
279:
278:
277:
271:
266:
262:
259:
255:
252:For example,
251:
250:
249:
247:
242:
240:
236:
233:
229:
226:
222:
218:
214:
210:
202:
181:
174:
157:
150:
141:
138:
122:
113:
107:
103:
91:
90:
89:
84:Functionality
83:
81:
79:
75:
71:
67:
63:
60:
56:
52:
44:
40:
34:
30:
19:
1228:Hemoproteins
1196:Translocases
1193:
1180:
1167:
1154:
1141:
1131:Transferases
1128:
1115:
972:Binding site
785:
729:
670:
660:
646:(6): 371–7.
643:
639:
632:
587:
583:
573:
561:. Retrieved
552:
461:histological
458:
454:
443:
440:Applications
431:
421:
416:
413:
401:
394:
390:Amyloid beta
388:
374:, Gpx3, and
353:
275:
243:
232:redox-active
206:
87:
73:
54:
50:
49:
29:
967:Active site
743:1.11.1.1-14
730:peroxidases
517:Hemoprotein
360:glutathione
280:Haem-using
258:active site
51:Peroxidases
18:Peroxidases
1217:Categories
1170:Isomerases
1144:Hydrolases
1011:Regulation
851:Deiodinase
689:Peroxibase
544:References
406:database.
404:PeroxiBase
241:residues.
163:Peroxidase
1223:EC 1.11.1
1049:EC number
873:1.11.1.15
463:markers.
315:Non-heme
209:substrate
123:−
70:peroxides
59:EC number
1073:Kinetics
997:Cofactor
960:Activity
766:Catalase
652:16955738
624:16492752
475:See also
428:Guaiacol
380:selenium
298:Catalase
235:cysteine
228:cofactor
219:such as
182:′
158:→
130:electron
104:′
78:oxidases
62:1.11.1.x
46:)
1183:Ligases
953:Enzymes
615:1413946
592:Bibcode
446:phenols
318:Thiol:
74:produce
66:enzymes
1157:Lyases
675:pages.
650:
622:
612:
563:30 May
1109:Types
736:1.11)
534:(MPO)
302:some
133:donor
1201:list
1194:EC7
1188:list
1181:EC6
1175:list
1168:EC5
1162:list
1155:EC4
1149:list
1142:EC3
1136:list
1129:EC2
1123:list
1116:EC1
665:2016
648:PMID
620:PMID
565:2019
376:Gpx4
372:Gpx2
368:Gpx1
354:The
225:heme
101:ROOR
43:1GP1
786:GPX
610:PMC
600:doi
588:103
237:or
211:is
171:ROH
53:or
39:PDB
1219::
734:EC
728::
644:42
642:.
618:.
608:.
598:.
586:.
582:.
471:.
370:,
322:,
186:OH
80:.
41::
1203:)
1199:(
1190:)
1186:(
1177:)
1173:(
1164:)
1160:(
1151:)
1147:(
1138:)
1134:(
1125:)
1121:(
945:e
938:t
931:v
911:6
906:5
901:4
896:3
891:2
886:1
879:)
875:(
824:8
819:7
814:6
809:5
804:4
799:3
794:2
789:1
732:(
718:e
711:t
704:v
654:.
626:.
602::
594::
567:.
179:R
175:+
151:+
147:H
142:2
139:+
119:e
114:2
108:+
57:(
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
