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characterized by a hard, nonpitting edema restricted to the forehead, glabella, upper eyelids, nose, and cheeks. This condition is also known as chronic upper facial erythematous edema, Morbihan's disease, morbus
Morbihan, and rosaceous lymphedema. Despite the name, it is unclear whether this
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Harneet Ranu, Joyce Lee and Tan Hiok Hee. "THERAPEUTIC HOTLINE: Successful treatment of
Morbihan's disease with oral prednisolone and doxycycline" (pages 682–685), Dermatologic Therapy. Article first published online: 3 November 2010
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Wohlrab J, et al. Persistent erythema and edema of the midthird and upper aspect of the face (morbus morbihan): evidence of hidden immunologic contact urticaria and impaired lymphatic drainage. J Am Acad
Dermatol.
101:. Generally, there are few symptomatic complaints aside from redness and facial contour changes. The edema typically worsens slowly over months to years and is often on a background of chronic inflammation.
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Nagasaka T, et al. Persistent lymphoedema in
Morbihan disease: formation of perilymphatic epithelioid cell granulomas as a possible pathogenesis. Clin Exp Dermatol. 2008;33(6):764-7.
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is usually necessary. Eyelid reduction surgery has also been reported to help with the cosmetic appearance of the condition, but does not alter the disease progression.
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Ajith C, et al. Granulomatous rosacea mimicking eyelid dermatitis. > OUCH! Indian J Dermatol
Venereol Leprol. 2005;71(5):366-5.
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therapy has been used, and the condition responds well to doses of 0.5 to 1 mg/kg/day. However, unlike in the treatment of
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Lamparter J, et al. Morbus
Morbihan: A rare cause of edematous swelling of the eyelids. Ophthalmologe. 2010;107(6):553-7.
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Freedberg IM, et al. Fitzpatrick's
Dermatology in General Medicine. Sixth Edition. McGraw-Hill, 2003:689-90.
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regimens commonly used for rosacea generally being ineffective. For the severe forms of this disease, oral
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Most cases of this condition tend to be recalcitrant to treatment, with topical and oral
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There are no specific laboratory findings associated with this condition, and the
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200:(2011), with the precision that the spelling in the United States is 'edema'.
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found on the areas involved, those mainly being the forehead,
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213:. (6th ed.). Page 689. McGraw-Hill.
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176:List of cutaneous conditions
41:Persistent oedema of rosacea
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33:Persistent edema of rosacea
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209:Freedberg, et al. (2003).
72:) is a hard, nonpitting
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115:differential diagnosis
70:rosaceous lymphedema
18:Rosaceous lymphedema
301:Acneiform eruptions
267:2005;52(4):595-602.
160:maintenance therapy
131:lupus erythematosus
94:cutaneous condition
88:Signs and symptoms
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182:References
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142:Treatment
117:includes
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170:See also
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