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Spermatocytic tumor is a rare tumour, making up only one to two percent of all testicular germ cell tumours. Men presenting with this tumour are generally 50 to 60 years old, and its occurrence is rare in men under 30 years old. Most present with slow, painless testicular enlargement, which may
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342:, so radical orchidectomy alone is sufficient treatment, and retroperitoneal lymph node dissection and adjuvant chemotherapy or radiotherapy are generally not required.
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The cells are generally packed into nodules, and have a loose, sheet-like arrangement that is commonly interrupted by interstitial oedema. Unlike classical
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of unspecified type (IGCNU). The intratubular growth probably accounts for the appearance of separate tumour nodules within the testis.
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320:. It has not been described as arising in locations outside the testis, and does not occur in association with other germ cell tumours.
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differentiation, most commonly as undifferentiated spindled cells intermingled within the typical-appearing spermatocytic tumor cells.
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Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005).
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appearance of the tumour is of a mutinodular grey-white to tan coloured mass with gelatinous,
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and, unlike seminoma and most other germ cell tumours, it does not arise from
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for most of the usual testicular germ cell tumour markers is negative (i.e.
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Intratubular growth of spermatocytic tumor can be seen, however there is
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Mills, S (ed.) 2009.Sternberg's
Diagnostic Pathology. 5th Edition.
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The name of the tumour comes from the similarity (under the
135:(or partial orchiectomy), done for a lesion suspicious for
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Spermatocytic tumors are diagnosed based on tissue from
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Müller J, Skakkebaek NE, Parkinson MC (February 1987).
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413:"The spermatocytic seminoma: views on pathogenesis"
310:Spermatocytic tumor is not considered a subtype of
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390:(7th ed.). St. Louis, Mo: Elsevier Saunders.
158:areas. The tumour may extend beyond the testis.
79:, previously called spermatocytic seminoma, is a
688:High-grade prostatic intraepithelial neoplasia
388:Robbins and Cotran pathologic basis of disease
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214:infiltrates are not seen. Cells undergoing
110:) between the small cells of the tumour and
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281:differentiation has also been described.
169:, spermatocytic tumors consist of three
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273:Rarely, spermatocytic tumors may show
16:Relatively benign tumour of the testis
330:Testicular Cancer - Treatment section
7:
218:are common, as are cells undergoing
700:List of people with prostate cancer
430:10.1111/j.1365-2605.1987.tb00176.x
195:medium-sized cells with prominent
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491:Spermatocytic seminoma micrograph
317:intratubular germ cell neoplasia
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230:intratubular germ cell neoplasia
338:, spermatocytic tumors rarely
240:placental alkaline phosphatase
1:
202:large cells (50-100 μm).
733:Extramammary Paget's disease
264:human chorionic gonadotropin
710:Transitional-cell carcinoma
612:Germ cell neoplasia in situ
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563:Sertoli–Leydig cell tumour
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296:of a spermatocytic tumor.
50:of a spermatocytic tumor.
755:Hirsuties coronae glandis
177:small cells with a large
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750:Erythroplasia of Queyrat
268:carcinoembryonic antigen
210:, fibrous septation and
112:secondary spermatocytes
99:), and classified as a
776:Male genital neoplasia
637:Endodermal sinus tumor
162:Histologic appearance
123:involve both testes.
705:Small-cell carcinoma
306:Relation to seminoma
279:Rhabdomyosarcomatous
199:(15-18 μm) and,
33:Spermatocytic tumour
632:Embryonal carcinoma
607:Spermatocytic tumor
568:Sertoli cell tumour
493:- webpathology.com.
77:Spermatocytic tumor
25:Spermatocytic tumor
745:Bowenoid papulosis
573:Leydig cell tumour
118:Signs and symptoms
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534:urogenital system
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375:978-0-7817-7942-5
334:Unlike classical
256:alpha fetoprotein
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19:Medical condition
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101:germ cell tumour
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740:Bowen's disease
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652:Choriocarcinoma
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555:gonadal stromal
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141:medical imaging
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458:Classification
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450:External links
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417:Int. J. Androl
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328:Main article:
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236:Immunostaining
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167:Histologically
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423:(1): 147–56.
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298:H&E stain
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532:of the male
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152:haemorrhagic
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340:metastasise
275:sarcomatoid
266:(hCG), and
212:lymphocytic
183:cytoplasmic
148:macroscopic
133:orchiectomy
30:Other names
346:References
294:Micrograph
108:microscope
48:Micrograph
728:Carcinoma
585:Germ cell
553:Sex cord–
544:Testicles
324:Treatment
220:apoptosis
127:Diagnosis
65:Pathology
60:Specialty
770:Category
675:Prostate
657:Embryoma
647:Teratoma
602:Seminoma
336:seminoma
312:seminoma
270:(CEA)).
244:vimentin
242:(PLAP),
208:seminoma
197:nucleoli
156:necrotic
81:neoplasm
477:M9063/3
439:3583416
258:(AFP),
216:mitosis
179:nuclear
95:of the
83:of the
69:urology
530:Tumors
437:
394:
373:
252:desmin
137:cancer
97:testis
93:tumour
85:testis
720:Penis
693:HGPIN
472:ICD-O
248:actin
188:(6-8
186:ratio
435:PMID
392:ISBN
371:ISBN
260:OCT4
181:-to-
171:cell
154:and
146:The
89:i.e.
425:doi
139:on
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624:NG
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421:10
419:.
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354:^
262:,
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250:,
246:,
227:no
222:.
192:),
190:μm
143:.
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91:a
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594:G
520:e
513:t
506:v
464:D
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87:(
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