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despite the positive results derived from small case-control studies, which have demonstrated that in the presence of these particular risk factors l-arginine may improve endothelial function, it is still unclear whether chronic administration of l-arginine has the potential to prevent the development of coronary atherosclerosis in high risk subjects. Furthermore, in conditions such as diabetes mellitus, the effect of l-arginine on endothelial function is rather weak, possibly because of the greater extent of eNOS ‘uncoupling’ in diabetic vessels. Therefore, before l-arginine is supplemented at a clinical level, it is important to determine, in detail, those clinical conditions which are accompanied by l-arginine deficiency.
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in this article does not contain a logical place for the word "review." I have identified the appropriate references in this article as review articles (as specified by NLM) by putting the word REVIEW after the page number -- since this is the only logical place to put this identifier that would not otherwise affect the format of the reference.
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finally found a paper studying the effect of arginine on HSV until I read that. I also find it interesting that a number of places online (all selling lysine) say that lysine inhibits HSV and that arginine promotes the reproduction of HSV-1. But this paper says just the opposite: that arginine inhibits the reproduction of HSV-1.
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pre-workout powder such as BSN N.O Xplode which was the product that started the entire trend of Nitric Oxide supplements.These powders usually contain some advanced form of
Arginine (Arginine AKG),a few other aminos that work in syergy with Arginine such as Orthinine & Citrulline and some type of stimulant,usually Caffeine.
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Not sure which name you are referring to, but "arginine" is not an IUPAC name. The IUPAC name is definitely listed under "other names." IUPAC names list each functional group and their position in the molecule, but "arginine" is a much simpler, commonly used name (which is why it is called a common
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The first section of this page concludes with the line: "In general, most people do not need to take arginine supplements because the body usually produces enough." I am not sure if I follow this logic here, as, in general, most people do not need to supplement their intake of any amino acid. Should
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fair enough but the article does state it may release prolactin. and that it is a precursor to NO. consider what viagra does wrt NO, and the role played by NO. also there has been newsreports of people who drank an energy drink (boost?) with ~1g arginine having a severe erection, and even resorting
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It seems to me that milk and chocolate are vegetarian. Now if we are trying to say vegetable sources, then milk is definitely not one, but what about chocolate? Chocolate does not necessarily include milk. In fact, I have in my hands right now a Trader Joe's organic dark chocolate 73% super dark bar
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2: Siasos G, Tousoulis D, Vlachopoulos C, Antoniades C, Stefanadi E, Ioakeimidis N, Andreou I, Zisimos K, Papavassiliou AG, Stefanadis C. Short-term treatment with L-arginine prevents the smoking-induced impairment of endothelial function and vascular elastic properties in young individuals. Int J
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Knowledge (XXG) standards express a clear preference for the use of review articles as references, and there are many good reasons for this. The
National Library of Medicine designates certain scientific journal articles in its database as review articles. The Knowledge (XXG) citation format used
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I'm taking L-arginine and it's a miracle supplement. I've sufferered from severe bloating and stomach pain for years and this helps that alot and gives me a lot of energy. Maybe it helps b/c it helps improve blood flow to my stomach and liver. It's worked miracles for me and I will keep taking it.
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About the
Prolactin issue,it should also state that SOME (some being the keyword here) bodybuilders stay away from free-form Arginine supplementation,on the other hand an entire supplement category exists around free-form Arginine.This category is called N.O supplementation.It usually consists of a
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Hi, very simple answer: You don't put anything into your condom. No instruction of use would ever recommend this. If you have blood-flow issues, refer to your normal doc and just say you want "more". There is a very good variety of ready and cheap substances available for helping your sex life. KR
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1: Siasos G, Tousoulis D, Vlachopoulos C, Antoniades C, Stefanadi E, Ioakeimidis N, Zisimos K, Siasou Z, Papavassiliou AG, Stefanadis C. The impact of oral L-arginine supplementation on acute smoking-induced endothelial injury and arterial performance. Am J Hypertens. 2009 Jun;22(6):586-92. Epub
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Just to let you know, the chemical strucutre you have listed for this molecule is wrong and you are not showing the charges that are located on two of the nitrogens. The group double bonded to the last carbon should be NH2 with a + charge (you have only NH) and also the amino group (-NH3) on the
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L-Arginine is the substrate of eNOS, and the main precursor of NO in the vascular endothelium. Clinical studies suggest that l-arginine improves endothelial function in the presence of certain atherosclerosis risk factors such as hypercholesterolemia, smoking and possibly hypertension. However,
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These supplements are very popular in the bodybuilding world due to the muscle volumizing effects they have when taken before a workout.Now regarding the
Prolactin issue,I think many either don't know or just don't care as they use the supplements strictly for the cosmetic "pump" it gives them.
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Reference 15 "Antiviral effect of arginine against herpes simplex virus type 1" studies arginine effect on HSV-1. The study was funded by
Ajinomoto Co. Inc. who just happens to sell arginine. The paper says the arginine used in the study was purchased from that same company. I was happy to have
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from 1963 the discussion section is very insightful. Within the paper it reads also "The results indicate that the lack of arginine or histidine, and possibly the presence of lysine, would interfere markedly with virus synthesis." I think this is worth to be added under
Research section. KR
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The solubility of L-arginine? Nice official data and diagrams. How about at least a mention of solubility characteristics? Typically g/dl and at several temperatures in water, ethanol, and sometimes a liquid in which the compound is unusually soluble. Or at at least a mention like: "Highly
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Healthy adults can synthesize arginine to meet needs, but children cannot, and so need to also be consuming arginine. The
Knowledge (XXG) article Essential Amino Acid clarifies the distinctions among essential amino acids, conditionally essential amino acids and non-essential amino acids.
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this say that most people do not need to obtain arginine from their diet because the body produces enough? I think using the word "supplements" has pharmaceutical connotations. The reference used is also problematic as it does not seem to apply specifically to this sentence.
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and give tissue an enlarged appearance for the duration of
Vasodilation; Especially highly vascularized tisues like lips and genitalia. I know there are lotions with Arginine for the penile area eg. Maxoderm and Private Pulse. Does anyone know products formulated for lips?
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Hi! I came across two papers reporting 4 and 6 cases of esophagitis due to l-arginine capsule retention in kids (PMID 32115583, PMID 28318704). Maybe it's worth mentioning in the relevant section of the article? There might be a mention in some review/book. Cheers,
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Arginine is widely used in sports supplementation. Adding some information on this subject should be relevant. I have started to take l'arginine in hopes of increasing my sexual stamina and for ED. I will keep you posted of the results. i'm not convinced yet.
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4: Siasos G, Tousoulis D, Antoniades C, Stefanadi E, Stefanadis C. L-Arginine, the substrate for NO synthesis: an alternative treatment for premature atherosclerosis? Int J Cardiol. 2007 Apr 4;116(3):300-8. Epub 2006 Jul 24. Review.
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Arginine is made in the urea cycle from citrulline, which can be derived from arginine via NO synthesis. That is a nice contribution into the topic of metabolic pathways, but doesn't explain the origin of carbon skeleton at all.
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Cardiovasc Med. 2007 May;4(5):274-83. Review.
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My wifw ia prescriberd ARG9 by infertiity specialist. of course may be to realase procatone or genral supplement. I also started ARG9 ti enhance sexual stamina. but results r waited. if anybody has more knowledge plz tell.
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It appears that the pKa values in the arginine article might be in the wrong order. PubChem (Arginine, C6H14N4O2 - PubChem) lists arginine pKa values as pK1 = 2.18, pK2 = 9.09, and pK3 = 13.2.
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which does not include any animal product. I can find no actual measurements of chocolate's arginine or lysine content. So does anyone have a source to back up chocolate being on this page?
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The referenced article indicates that arginine is synthesized from ornithine (as does discussion on the
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The protonation state shown is impossible. Any conditions acidic enough to protonate the carboxyl would also protonate the amine and guanido...
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Can somebody please explain why is it so evidently that the need for this amino-acid is restricted to children ? Same for histidine. Thanks.
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i know the article indicates these things but the picture at the top should also point to this charge and resonance using dotted lines
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Section now has as reference a meta-analysis (fancy review) that cites 18 clinical trials. Claim appears to be supported by research.
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Isn't it supposed to have a fixed +1 charge in the amino acid side chain? there is resonance between the nitrogen atoms as well.
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There should be a section discussing whether Arginine actually increases bloodflow / potential safety of use in condoms. (see
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Yes, only one pKa is listed, whereas the compound has 3 relevant values. I am fixing this and deleting the redundant pKb.
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Excellent point, but the same problem affects the images of all the amino acids, not just arginine. I'll bring it up at
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I removed the following uncited claimed benefits of supplementation. L-Arginine is being aggressively marketed as a
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P.S I am very new to this Knowledge (XXG) thing,if I did not enter what I wrote in the right place I apologize.
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I believe there is a tidbit about calcium carbonate+arginine on another wikipedia page for sensitive teeth.
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The second picture has a NH2 that appears to be bound by its H, when in fact it is bound by the N of NH2.
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Hey,try taking some Citrulline in combination with the Arginine.The two aminos will work together great.
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http://www.colgateprofessional.co.uk/professionaleducation/Pro-Argin-Technology-Mode-Of-Action/article
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I removed the reference to the gut-kidney axis, which is about morbidity, and not the healthy body.
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The pKa should be changed from 2.48 to 12.48 (and the pKb should be changed accordingly). Thanks.
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etc.? Could someone add some non-meat sources or a link to where one can find such information --
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Raised something else in me, perhaps this is related to the erectile dysfunction use case?
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I concur. Also: the mentioned paper does not appear in the Herpes#Treatment section.
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Why does it occur only in Canadian bacon - are pigs everywhere else arginine-free?
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This is a different subject and would just make the L-Arginine article bloated.
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alpha carbon (the carbon next the carboxyl group) should have a + charge on it.
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https://www.kidneywi.org/wp-content/uploads/2020/11/PM-6-The-Kidney-Gut-axis.pdf
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I believe it would be better to show arginine with the side chain charged.
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has a chemical formula of C9H11NO2 but a molecular forumla of C6H5CH2CHCOOH
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It's well proven, Colgate was the original sponsor of the research as well.
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Struggling to reconcile this with reality, but just thought I'd raise it :
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Increases blood circulation throughout the body, including the sex organs
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OP posted this on several amino acid pages; please see discussion here:
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Apparently it's in shampoo - I just saw J-lo on tv and she said so.
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Alleviates male infertility, improving sperm production and motility
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straight chain, the distal end of which is capped by a complex
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http://www.condomdepot.com/product/detail.cfm/nid/190/pid/3422
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Safety: several cases of esophagitis due to capsule retention
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Arginine is used in many cosmetic products to increase
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B-Class vital articles in Biology and health sciences
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Cardiol. 2008 Jun 6;126(3):394-9. Epub 2007 Jun 22.
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1733:Polar Apposite
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1710:175.107.218.79
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1199:24.166.216.135
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1507:
1498:
1497:Phenylalanine
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52:Learn to edit
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1753:CopperKettle
1749:
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1561:— Preceding
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1504:— Preceding
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1434:— Preceding
1407:— Preceding
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1381:— Preceding
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1312:— Preceding
1300:
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1081:Vasodilation
1078:
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932:
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882:
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585:— Preceding
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484:project page
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393:project page
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220:WikiProjects
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94:
19:This is the
1611:enantiomers
1413:209.6.35.15
1193:—Preceding
1153:sensitivity
1050:guanidinium
1008:—Preceding
974:—Preceding
908:—Preceding
904:cut of meat
857:Sussmanbern
836:—Preceding
782:Sexual uses
762:—Preceding
712:David notMD
688:David notMD
649:—Preceding
627:81.57.60.23
472:is part of
148:free images
31:not a forum
1769:Categories
1731:explains.
1671:Mikestorm1
1640:in the gut
1440:Pain-proof
1115:. Thanks,
1042:side chain
1039:amino acid
993:Truckhence
810:Other uses
741:IUPAC Name
591:68.15.4.17
1592:Myoglobin
1109:citations
1086:Alphaman7
1046:aliphatic
1032:Structure
398:Chemicals
388:chemicals
351:Chemicals
208:is rated
88:if needed
71:Be polite
21:talk page
1688:Mdewman6
1615:Kortoso
1575:contribs
1563:unsigned
1518:contribs
1506:unsigned
1448:contribs
1436:unsigned
1409:unsigned
1383:unsigned
1314:unsigned
1308:16860889
1296:17457351
1284:17588688
1272:19300425
1223:Danski14
1195:unsigned
1142:Reduces
1105:cure-all
1022:contribs
1010:unsigned
976:unsigned
949:contribs
937:unsigned
910:unsigned
887:unsigned
838:unsigned
764:unsigned
760:name).
701:Untitled
651:unsigned
587:unsigned
560:unsigned
539:unsigned
469:Arginine
56:get help
29:This is
27:article.
25:Arginine
1650:Eris8x6
1567:JosephV
1459:Shampoo
1340:Mykstor
1151:insulin
1144:adipose
425:on the
210:B-class
154:WP refs
142:scholar
1534:Jytdog
1476:Sgt101
1361:Vokesk
1117:Vectro
1062:Tualha
1052:group.
733:Renduy
674:Kasooi
216:scale.
126:Google
1174:X5dna
1058:three
876:Mig77
792:Boris
607:paper
197:This
169:JSTOR
130:books
84:Seek
1757:talk
1737:talk
1714:talk
1692:talk
1675:talk
1654:talk
1619:talk
1596:talk
1571:talk
1538:talk
1531:here
1514:talk
1495:Eg:
1480:talk
1444:talk
1417:talk
1391:talk
1365:talk
1344:talk
1322:talk
1305:PMID
1293:PMID
1281:PMID
1269:PMID
1248:talk
1240:Done
1203:talk
1178:talk
1121:talk
1090:talk
1066:Talk
1037:The
1018:talk
984:talk
945:talk
918:talk
895:talk
861:talk
846:talk
788:that
772:talk
751:Borb
716:talk
692:talk
678:talk
659:talk
631:talk
616:talk
595:talk
568:talk
547:talk
162:FENS
136:news
73:and
1427:pKa
1401:pKa
1310:.
1111:to
960:. —
951:) .
508:???
417:Mid
298:???
244:MCB
176:TWL
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