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with a cylindrical blade. It can be of one of several dimensions and designs depending on what it is meant to be used for. They may be specially designed for obtaining a cylindrically shaped core of
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a skull, ca. 1664, in one of the earliest
American portraits. Clarke has a trephine in his right hand. The painting is in
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as it lay in the bone and is a useful diagnostic tool in certain circumstances such as bone marrow cancer and leukemia.
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A trephine with a center pin can be seen on the left.
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207:A Greek–English Lexicon
81:; from Greek τρύπανον,
174:(September 18, 2008).
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