Knowledge (XXG)

Toponomics

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Schubert, Walter; Bonnekoh, Bernd; Pommer, Ansgar J; Philipsen, Lars; Böckelmann, Raik; Malykh, Yanina; Gollnick, Harald; Friedenberger, Manuela; Bode, Marcus; Dress, Andreas W M (1 October 2006). "Analyzing proteome topology and function by automated multidimensional fluorescence microscopy".
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of organisms. It is the field of study that purposes to decode the complete toponome in health and disease (the human toponome project)—which is the next big challenge in human
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with parameter- and dimension-unlimited functional resolution. The resulting toponome structures are hierarchically organized and can be described by a three symbol code.
498: 237: 173: 428:"Direct, spatial imaging of randomly large supermolecules by using parameter unlimited TIS imaging cycler microscopy" 17: 491: 103: 83: 517: 532: 484: 302: 76: 408: 359: 191: 527: 400: 351: 233: 179: 169: 468: 390: 379:"A three-symbol code for organized proteomes based on cyclical imaging of protein locations" 343: 310: 269: 225: 161: 203: 68: 41: 306: 522: 456: 511: 57: 363: 412: 45: 229: 125: 72: 291:""Mapping togetherness" (research highlight referring to Schubert et al. 2006)" 128:
addressing the fact that the spatial network of biomolecules in cells follows
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The spatial organization of biomolecules in cells is directly revealed by
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were introduced in 2003 by Walter Schubert based on observations with
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Knowledge (XXG) talk:Articles for creation/Toponomics
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Topological Proteomics, Toponomics, MELK-Technology
492: 8: 499: 485: 433:. International Microscopy Conference 2013 394: 314: 273: 224:. Springer New York. pp. 2191–2212. 141: 60:after having decoded the human genome. 328: 326: 251: 249: 215: 213: 199: 189: 151: 149: 147: 145: 112:derived from the ancient Greek nouns 7: 453: 451: 132:rules enabling coordinated actions. 27:Study of protein networks in biology 471:. You can help Knowledge (XXG) by 220:Schubert, W (2013). "Toponomics". 160:. Vol. 83. pp. 189–209. 25: 455: 116:(τόπος, 'place, position') and ' 104:imaging cycler microscopes (ICM) 222:Encyclopedia of Systems Biology 377:Schubert, Walter (June 2007). 256:Cottingham, Katie (May 2008). 1: 230:10.1007/978-1-4419-9863-7_631 289:Abott, A (12 October 2006). 262:Journal of Proteome Research 52:concerning the study of the 71:code of proteins and other 549: 450: 79:intact cells and tissues. 29: 84:imaging cycler microscopy 120:' (νόμος, 'law'). Hence 30:Not to be confused with 166:10.1007/3-540-36459-5_8 46:molecular cell biology 396:10.1002/cyto.a.20281 336:Nature Biotechnology 156:Schubert, W (2003). 307:2006Natur.443..608. 40:is a discipline in 480: 479: 342:(10): 1270–1278. 301:(7112): 608–609. 275:10.1021/pr083701k 239:978-1-4419-9862-0 175:978-3-540-00546-9 16:(Redirected from 540: 501: 494: 487: 459: 452: 442: 441: 439: 438: 432: 423: 417: 416: 398: 383:Cytometry Part A 374: 368: 367: 330: 321: 320: 318: 286: 280: 279: 277: 253: 244: 243: 217: 208: 207: 201: 197: 195: 187: 153: 126:descriptive term 21: 548: 547: 543: 542: 541: 539: 538: 537: 518:Systems biology 508: 507: 506: 505: 448: 446: 445: 436: 434: 430: 425: 424: 420: 376: 375: 371: 348:10.1038/nbt1250 332: 331: 324: 316:10.1038/443608a 288: 287: 283: 255: 254: 247: 240: 219: 218: 211: 198: 188: 176: 155: 154: 143: 138: 92: 77:morphologically 69:spatial network 42:systems biology 35: 28: 23: 22: 15: 12: 11: 5: 546: 544: 536: 535: 530: 525: 520: 510: 509: 504: 503: 496: 489: 481: 478: 477: 460: 444: 443: 418: 389:(6): 352–360. 369: 322: 281: 245: 238: 209: 200:|journal= 174: 140: 139: 137: 134: 91: 88: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 545: 534: 533:Biology stubs 531: 529: 526: 524: 521: 519: 516: 515: 513: 502: 497: 495: 490: 488: 483: 482: 476: 474: 470: 467:article is a 466: 461: 458: 454: 449: 429: 426:Schubert, W. 422: 419: 414: 410: 406: 402: 397: 392: 388: 384: 380: 373: 370: 365: 361: 357: 353: 349: 345: 341: 337: 329: 327: 323: 317: 312: 308: 304: 300: 296: 292: 285: 282: 276: 271: 267: 263: 259: 252: 250: 246: 241: 235: 231: 227: 223: 216: 214: 210: 205: 193: 185: 181: 177: 171: 167: 163: 159: 152: 150: 148: 146: 142: 135: 133: 131: 127: 123: 119: 115: 111: 107: 105: 101: 97: 89: 87: 85: 80: 78: 74: 70: 66: 61: 59: 58:biotechnology 55: 51: 47: 43: 39: 33: 19: 473:expanding it 462: 447: 435:. Retrieved 421: 386: 382: 372: 339: 335: 298: 294: 284: 265: 261: 221: 157: 121: 117: 113: 109: 108: 99: 95: 93: 81: 73:biomolecules 64: 62: 37: 36: 268:(5): 1806. 130:topological 512:Categories 437:2013-09-23 136:References 122:toponomics 100:toponomics 94:The terms 38:Toponomics 202:ignored ( 192:cite book 90:Etymology 50:histology 528:Topology 405:17326231 364:30436820 356:17013374 184:12934931 110:Toponome 96:toponome 65:toponome 54:toponome 32:Toponymy 465:biology 413:3132423 303:Bibcode 67:is the 411:  403:  362:  354:  295:Nature 236:  182:  172:  48:, and 523:Omics 463:This 431:(PDF) 409:S2CID 360:S2CID 124:is a 118:nomos 114:topos 469:stub 401:PMID 352:PMID 234:ISBN 204:help 180:PMID 170:ISBN 98:and 391:doi 387:71A 344:doi 311:doi 299:443 270:doi 226:doi 162:doi 75:in 514:: 407:. 399:. 385:. 381:. 358:. 350:. 340:24 338:. 325:^ 309:. 297:. 293:. 264:. 260:. 248:^ 232:. 212:^ 196:: 194:}} 190:{{ 178:. 168:. 144:^ 106:. 63:A 44:, 500:e 493:t 486:v 475:. 440:. 415:. 393:: 366:. 346:: 319:. 313:: 305:: 278:. 272:: 266:7 242:. 228:: 206:) 186:. 164:: 34:. 20:)

Index

Knowledge (XXG) talk:Articles for creation/Toponomics
Toponymy
systems biology
molecular cell biology
histology
toponome
biotechnology
spatial network
biomolecules
morphologically
imaging cycler microscopy
imaging cycler microscopes (ICM)
descriptive term
topological




doi
10.1007/3-540-36459-5_8
ISBN
978-3-540-00546-9
PMID
12934931
cite book
help


doi
10.1007/978-1-4419-9863-7_631

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