Knowledge (XXG)

Vasopressin

Source 📝

931: 908: 553: 3139:) to increase the blood pressure while sparing the use of catecholamines. These argipressins have much shorter elimination half-life (around 20 minutes) comparing to synthetic non-arginine vasopresines with much longer elimination half-life of many hours. Further, argipressins act on V1a, V1b, and V2 receptors which consequently lead to higher eGFR and lower vascular resistance in the lungs. A number of injectable arginine vasopressins are currently in clinical use in the United States and in Europe. 805: 830: 5918: 688:
InChI=1S/C46H65N15O12S2 /c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1
5873: 1182: 937: 836: 713: 54: 5903: 5888: 2558: 636: 2538: 45: 2282:), stimulates secretion, even in the face of decreased osmolality of the plasma: it supersedes osmolality, but with a milder effect. In other words, vasopressin secretion is also stimulated in the presence of hypoosmolality (hyponatremia) when the arterial blood volume is low by the unloading of 3420:
Evidence for an effect of AVP on monogamy vs polygamy comes from experimental studies in several species, which indicate that the precise distribution of vasopressin and vasopressin receptors in the brain is associated with species-typical patterns of social behavior. In particular, there are
2644:
is very similar to that of the vasopressins: It is also a nonapeptide with a disulfide bridge and its amino acid sequence differs at only two positions. The two genes are located on the same chromosome separated by a relatively small distance of less than 15,000 bases in most species. The
2649:
that secrete vasopressin are adjacent to magnocellular neurons that secrete oxytocin, and are similar in many respects. The similarity of the two peptides can cause some cross-reactions: oxytocin has a slight antidiuretic function, and high levels of AVP can cause uterine contractions.
2056:
Increasing the water permeability of distal convoluted tubule (DCT) and cortical collecting tubules (CCT), as well as outer and inner medullary collecting duct (OMCD & IMCD) in the kidney, thus allowing water reabsorption and excretion of more concentrated urine, i.e.,
2069:
of collecting tubule and collecting duct epithelial cells. Aquaporins allow water to move down their osmotic gradient and out of the nephron, increasing the amount of water re-absorbed from the filtrate (forming urine) back into the bloodstream. This effect is mediated by
4681:
Höglund OV, Hagman R, Olsson K, Olsson U, Lagerstedt AS (October 2014). "Intraoperative changes in blood pressure, heart rate, plasma vasopressin, and urinary noradrenalin during elective ovariohysterectomy in dogs: repeatability at removal of the 1st and 2nd ovary".
2001:
and causes the kidneys to reabsorb solute-free water and return it to the circulation from the tubules of the nephron, thus returning the tonicity of the body fluids toward normal. An incidental consequence of this renal reabsorption of water is concentrated
737:, ADH, ARVP, AVP-NPII, AVRP, VP, AVP gene, AVP (gene), Prepro-AVP-NP II, arginine vasopressin gene, vasopressin gene, prepro-arginine-vasopressin-neurophysin II gene, vasopressin-neurophysin II-copeptin, vasopressin-neurophysin 2-copeptin, prepro-AVP2 2309:
within neurosecretory granules that are found within Herring bodies, localized swellings of the axons and nerve terminals. These carry the peptide directly to the posterior pituitary gland, where it is stored until released into the blood.
3503:: When the blood flow through the juxtaglomerular apparatus decreases, blood pressure is considered low, and the adrenal cortex secretes aldosterone to increase sodium reabsorption in the collecting duct, thereby increasing blood pressure. 3363:
but also a number of other tumors. A variety of diseases affecting the brain or the lung (infections, bleeding) can be the driver behind SIADH. A number of drugs have been associated with SIADH, such as certain antidepressants
3421:
consistent differences between monogamous species and polygamous species in the distribution of AVP receptors, and sometimes in the distribution of vasopressin-containing axons, even when closely related species are compared.
8447: 2136:. Vasopressin stimulates sodium chloride reabsorption in the thick ascending limb of the nephron by activating signaling pathways. Vasopressin increases the traffic of NKCC2 to the membrane and phosphorylates some 4717:
Goldmann A, Hoehne C, Fritz GA, Unger J, Ahlers O, Nachtigall I, et al. (September 2008). "Combined vs. Isoflurane/Fentanyl anesthesia for major abdominal surgery: Effects on hormones and hemodynamics".
4599:"Vasopressin stimulation of adrenocorticotropin hormone (ACTH) in humans. In vivo bioassay of corticotropin-releasing factor (CRF) which provides evidence for CRF mediation of the diurnal rhythm of ACTH" 8440: 5750:
Iovino M, Messana T, De Pergola G, Iovino E, Dicuonzo F, Guastamacchia E, et al. (2018). "The Role of Neurohypophyseal Hormones Vasopressin and Oxytocin in Neuropsychiatric Disorders".
3318:
Decreased AVP release (neurogenic — i.e. due to alcohol intoxication or tumour) or decreased renal sensitivity to AVP (nephrogenic, i.e. by mutation of V2 receptor or AQP) leads to
5917: 3458: 3352: 3347: 2144:
sites on the cytoplasmic N-terminal of the NKCC2 located in the membrane, increasing its activity. Increased NKCC2 activity aids in water reabsorption in the collecting duct through
8433: 2345:, predominantly during abdominal surgery, especially at gut manipulation, traction of viscera, as well as abdominal insufflation with carbon dioxide during laparoscopic surgery. 128: 3515:: When the stretch receptors in the aortic arch and carotid sinus increase, the blood pressure is considered to be elevated and the heart rate decreases to lower blood pressure. 5462:
Joo KW, Jeon US, Kim GH, Park J, Oh YK, Kim YS, et al. (October 2004). "Antidiuretic action of oxytocin is associated with increased urinary excretion of aquaporin-2".
4488:
Wang XM, Dayanithi G, Lemos JR, Nordmann JJ, Treistman SN (November 1991). "Calcium currents and peptide release from neurohypophysial terminals are inhibited by ethanol".
944: 843: 3969: 2074:. Vasopressin also increases the concentration of calcium in the collecting duct cells, by episodic release from intracellular stores. Vasopressin, acting through 7674: 6273: 6245: 6142: 2174:
Recent evidence suggests that vasopressin may have analgesic effects. The analgesia effects of vasopressin were found to be dependent on both stress and sex.
2021:
ventral forebrain regions have been shown to facilitate and coordinate reward circuits during partner preference formation, critical for pair bond formation.
7594: 660: 7721: 5799: 4518:
Matsukawa T, Miyamoto T (March 2011). "Angiotensin II-stimulated secretion of arginine vasopressin is inhibited by atrial natriuretic peptide in humans".
6776: 1595: 5611:
Verbalis JG, Goldsmith SR, Greenberg A, Schrier RW, Sterns RH (November 2007). "Hyponatremia treatment guidelines 2007: expert panel recommendations".
1576: 766: 2266:
The physiological stimulus for secretion of vasopressin is increased osmolality of the plasma, monitored by the hypothalamus. A decreased arterial
7220: 6101: 4747:"Stress hormone responses to major intra-abdominal surgery during and immediately after sevoflurane-nitrous oxide anaesthesia in elderly patients" 2298: 2202: 171: 4864:
Melville RJ, Forsling ML, Frizis HI, LeQuesne LP (December 1985). "Stimulus for vasopressin release during elective intra-abdominal operations".
2499:(AQP2) channels (water channels). This allows water to be reabsorbed down an osmotic gradient, and so the urine is more concentrated. Release of 2239:(alcohol) reduces the calcium-dependent secretion of AVP by blocking voltage-gated calcium channels in neurohypophyseal nerve terminals in rats. 9213: 6823: 5872: 5342: 9198: 9188: 6343: 5852: 5809: 5397: 5356: 5049: 4578:
Garrahy A, Thompston CJ (2019). "General Principles, Diabetes, Metabolism, Obesity, Gastrointestinal Hormones, Aging, Endocrine Toxicology".
4562: 3996: 3736: 3704: 3622: 3593: 6025: 7839: 3575: 2078:, also increases transcription of the aquaporin-2 gene, thus increasing the total number of aquaporin-2 molecules in collecting duct cells. 4907:
Moran WH, Miltenberger FW, Shuayb WA, Zimmermann B (July 1964). "The Relationship of Antidiuretic Hormone Secretion to Surgical Stress".
2294: 5986: 5573:
Baum S, Nusbaum M (March 1971). "The control of gastrointestinal hemorrhage by selective mesenteric arterial infusion of vasopressin".
930: 5958: 5497:
Acher R, Chauvet J (July 1995). "The neurohypophysial endocrine regulatory cascade: precursors, mediators, receptors, and effectors".
1802: 5902: 2646: 2314: 1795: 680: 907: 5206:"Social motivation is reduced in vasopressin 1b receptor null mice despite normal performance in an olfactory discrimination task" 8858: 8714: 6446: 2439: 2381: 3925:
Lim MM, Young LJ (2004). "Vasopressin-dependent neural circuits underlying pair bond formation in the monogamous prairie vole".
8962: 8667: 7714: 7584: 6869: 6020: 5887: 3562: 3541: 3474: 3397: 2474: 2210: 2102: 668:
c1ccc(cc1)C2C(=O)N(C(=O)N(C(=O)N(CSSC(C(=O)N(C(=O)N2)Cc3ccc(cc3)O)N)C(=O)N4CCC4C(=O)N(CCCN=C(N)N)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
330: 3251:, sensitivity to the drug, asthma, seizures, heart failure, a comatose state, migraine headaches, and cardiovascular disease. 8138: 7167: 6769: 6552: 6175: 6111: 6005: 2483: 2133: 2075: 1957: 829: 804: 5067:"Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice" 3558: 2221:
in order to reduce Per2 protein levels in the cell. At the same time, Per2 also inhibits the transcription factors for the
7808: 7086: 6567: 6035: 6010: 2117: 3537: 3497:: When the atrium stretches, blood pressure is considered to be increased and sodium is excreted to lower blood pressure. 3239:
The use of lysine vasopressin is contraindicated in the presence of hypersensitivity to beef or pork proteins, increased
8158: 8133: 7773: 7599: 6624: 6619: 6361: 6076: 3365: 746: 452: 2313:
There are other sources of AVP, beyond the hypothalamic magnocellular neurons. For example, AVP is also synthesized by
9203: 7213: 7145: 6854: 6106: 6086: 3396:). Finally, it can occur without a clear explanation. Hyponatremia can be treated pharmaceutically through the use of 2462: 532: 4646:
Day TA, Sibbald JR (June 1990). "Noxious somatic stimuli excite neurosecretory vasopressin cells via A1 cell group".
7707: 7094: 6949: 6874: 6864: 6732: 6614: 3494: 2248: 943: 842: 7021: 6789: 3802:"The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior" 3721: 9208: 8226: 7913: 7844: 7619: 7177: 7104: 7061: 6849: 6762: 6737: 6295: 5845: 5157:"The hypothalamic-pituitary-adrenal axis response to stress in mice lacking functional vasopressin V1b receptors" 3438: 3360: 3278: 2322: 2290: 2006:
and reduced urine volume. AVP released in high concentrations may also raise blood pressure by inducing moderate
4153:"Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCC" 3100:
is used in conditions featuring low vasopressin secretion, as well as for control of bleeding (in some forms of
936: 835: 9233: 8163: 7066: 6902: 6813: 6366: 5815: 5348: 3500: 3369: 3077: 2098: 1921:). AVP has two primary functions. First, it increases the amount of solute-free water reabsorbed back into the 1640: 754: 22: 3089:
Vasopressin has off-label uses and is used in the treatment of vasodilatory shock, gastrointestinal bleeding,
401: 8276: 8168: 7834: 7172: 6907: 6595: 3968:
Chapman IM, Professor of Medicine, Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital.
3152: 3096:
Vasopressin agonists are used therapeutically in various conditions, and its long-acting synthetic analogue
3090: 2362: 2165: 1621: 198: 191: 186: 8535: 5294:"Vasopressin-induced von Willebrand factor secretion from endothelial cells involves V2 receptors and cAMP" 4821:
Nussey SS, Page SR, Ang VT, Jenkins JS (March 1988). "The response of plasma oxytocin to surgical stress".
3509:: In response to stretching of the right atrium wall, heart rate increases, lowering venous blood pressure. 9223: 9193: 8281: 8148: 8128: 8093: 7993: 7669: 7206: 6441: 6418: 6170: 5951: 5620: 3156: 3101: 2090: 272: 205: 521: 9228: 8271: 8188: 7803: 7109: 7028: 5381: 4973: 3224: 2500: 2424: 818: 392: 29: 5253:"Desmopressin induces endothelial P-selectin expression and leukocyte rolling in postcapillary venules" 3021: 2990: 8705: 8460: 8198: 8173: 7793: 7788: 7644: 7639: 7629: 7614: 7134: 7114: 7099: 6754: 5838: 3469: 2508: 2444: 2386: 2245:
II stimulates AVP secretion, in keeping with its general pressor and pro-volumic effects on the body.
2040:
and its synthetic version was used in human AVP deficiency, although it has been largely replaced by
299: 5625: 2201:
expression which is managed by major clock controlled genes. In this circadian circuit known as the
8585: 7471: 7053: 7010: 6994: 6912: 6859: 6727: 6333: 6328: 6300: 6263: 6096: 6081: 6045: 3612: 3409: 3168: 3148: 2013:
AVP also may have a variety of neurological effects on the brain. It may influence pair-bonding in
1938: 1906: 733: 548: 347: 235: 9031: 8942: 8937: 8793: 8788: 7278: 5926:: CRYSTAL STRUCTURE OF BOVINE NEUROPHYSIN II COMPLEXED WITH THE VASOPRESSIN ANALOGUE PHE-TYR AMIDE 5252: 3037: 2251:
inhibits AVP secretion, in part by inhibiting Angiotensin II-induced stimulation of AVP secretion.
8530: 8525: 8463: 8178: 8019: 7998: 7947: 7303: 7071: 7000: 6068: 5775: 5681: 5522: 5233: 5137: 4965: 4889: 4846: 4470: 4421: 4372: 4280: 3950: 3782: 3677: 3484: 3319: 3307: 3212: 3160: 3117: 3083: 3055: 2826: 2326: 2302: 1922: 778: 167: 9095: 9090: 9046: 8647: 8642: 8597: 8547: 8515: 8495: 8485: 5549: 4786:
Haas M, Glick SM (May 1978). "Radioimmunoassayable plasma vasopressin associated with surgery".
2910: 1778: 1757: 1731: 1710: 9115: 8932: 8803: 8783: 8632: 8627: 8607: 8425: 5251:
Kanwar S, Woodman RC, Poon MC, Murohara T, Lefer AM, Davenpeck KL, et al. (October 1995).
2972: 2874: 2839: 9134: 9110: 9105: 9100: 9066: 8952: 8848: 8471: 8456: 7988: 7962: 7308: 7247: 7129: 7124: 7038: 6897: 6255: 5944: 5805: 5767: 5732: 5673: 5638: 5590: 5514: 5479: 5444: 5393: 5352: 5323: 5274: 5225: 5186: 5129: 5088: 5045: 5022: 4957: 4916: 4881: 4838: 4803: 4768: 4727: 4699: 4663: 4628: 4558: 4535: 4497: 4462: 4413: 4364: 4329: 4272: 4231: 4182: 4133: 4092: 4051: 4002: 3992: 3942: 3907: 3880: 3831: 3774: 3732: 3700: 3669: 3618: 3506: 2954: 2892: 2512: 2479: 2094: 726: 212: 8917: 5373: 5108:"Vasopressin 1a receptor knockout mice have a subtle olfactory deficit but normal aggression" 3082:
Vasopressin is used to manage anti-diuretic hormone deficiency. Vasopressin is used to treat
501: 9061: 8843: 8838: 8823: 8685: 8567: 8392: 8349: 8143: 7730: 7150: 6892: 6818: 6785: 6222: 6217: 5759: 5722: 5712: 5665: 5630: 5582: 5506: 5471: 5434: 5426: 5385: 5313: 5305: 5264: 5217: 5176: 5168: 5119: 5078: 5012: 5004: 4947: 4873: 4830: 4795: 4758: 4691: 4655: 4618: 4610: 4527: 4452: 4403: 4356: 4319: 4311: 4262: 4221: 4213: 4172: 4164: 4123: 4082: 4041: 4033: 3934: 3870: 3862: 3821: 3813: 3766: 3659: 3651: 3442: 3228: 3163:
depends on the mode of administration and ranges from thirty minutes to two hours. It has a
2822: 2408: 2161: 2086: 2007: 1983: 1918: 1910: 1023: 954: 898: 853: 569: 441: 264: 162: 71: 8612: 4441:"A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock" 3065:†Vasotocin is the evolutionary progenitor of all the vertebrate neurohypophysial hormones. 2289:
The AVP that is measured in peripheral blood is almost all derived from secretion from the
461: 356: 9218: 8505: 8344: 7634: 7359: 7349: 6828: 6547: 6180: 5975: 3282: 3270: 3167:
of ten to twenty minutes. It is widely distributed throughout the body and remains in the
3113: 2489: 2453: 2342: 2338: 2318: 2306: 2125: 2066: 1953: 998: 552: 282: 247: 4799: 1316:
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
774: 5204:
Wersinger SR, Kelliher KR, Zufall F, Lolait SJ, O'Carroll AM, Young WS (December 2004).
4347:
Wiltshire T, Maixner W, Diatchenko L (December 2011). "Relax, you won't feel the pain".
3851:"Neurohypophyseal Hormones: Novel Actors of Striated Muscle Development and Homeostasis" 3729:
Handbook of Neurochemistry and Molecular Neurobiology: Neuroactive Proteins and Peptides
1181: 9166: 9125: 8690: 8406: 8024: 7967: 7932: 7798: 7654: 7649: 7382: 7377: 7354: 7256: 6959: 6699: 6668: 6640: 6585: 6480: 6197: 6128: 5727: 5700: 5439: 5414: 5389: 5181: 5156: 5017: 5008: 4992: 4834: 4324: 4299: 4226: 4201: 4177: 4152: 4087: 4070: 4046: 4021: 3938: 3875: 3850: 3826: 3801: 3664: 3639: 3300: 3292: 3260: 3244: 3136: 2618: 2341:
for evaluation of surgical techniques. Plasma vasopressin concentration is elevated by
1968: 1942: 712: 53: 5763: 5413:
Li C, Wang W, Summer SN, Westfall TD, Brooks DP, Falk S, et al. (February 2008).
5318: 5293: 4623: 4598: 4457: 4440: 4408: 4391: 3179:. Arginin vasopressins for use in septic shock are intended for intravenous use only. 1510: 1505: 1500: 1495: 1490: 1485: 1480: 1475: 1470: 1465: 1460: 1455: 1450: 1445: 1440: 1435: 1430: 1425: 1420: 1415: 1410: 1405: 1400: 1395: 1390: 1385: 1380: 1375: 1370: 1365: 1360: 1355: 1350: 1345: 1340: 1335: 1330: 1325: 1320: 1315: 1299: 1294: 1289: 1284: 1279: 1274: 1258: 1253: 1248: 1243: 1238: 1233: 1228: 1223: 9182: 9162: 8397: 8324: 8039: 7768: 7331: 7326: 7293: 7141: 6979: 6969: 6709: 6485: 6187: 6150: 5124: 5107: 4695: 4659: 4376: 4267: 4250: 3446: 3389: 3373: 3323: 3266: 3128: 3105: 2626: 2586: 2283: 2279: 2121: 2113: 1998: 1210: 153: 5685: 5526: 5292:
Kaufmann JE, Oksche A, Wollheim CB, Günther G, Rosenthal W, Vischer UM (July 2000).
5237: 5141: 4893: 4850: 4425: 3954: 3786: 3681: 3433:
effects on pain perception and cognitive function. Vasopressin also plays a role in
2557: 9006: 8976: 8892: 8872: 8748: 8378: 8358: 8213: 8080: 8003: 7905: 7659: 7535: 7530: 7525: 7520: 7487: 7482: 7233: 7005: 6844: 6492: 6428: 6413: 6376: 6323: 6290: 6030: 5997: 5779: 5701:"A review of the nonpressor and nonantidiuretic actions of the hormone vasopressin" 4969: 4474: 4284: 3489: 3393: 3124: 3109: 3097: 2939: 2915: 2736: 2715: 2537: 2518: 2267: 2225:
gene in order to regulate its expression, the expression of vasopressin, and other
2058: 2041: 2018: 1898: 1016: 795: 381: 228: 141: 136: 44: 7865: 5269: 4520:
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
758: 5634: 4439:
Jin X, Shearman LP, Weaver DR, Zylka MJ, de Vries GJ, Reppert SM (January 1999).
4315: 4168: 3849:
Costa A, Rossi E, Scicchitano BM, Coletti D, Moresi V, Adamo S (September 2014).
3817: 2577:(nonapeptides). The amino acid sequence of arginine vasopressin (argipressin) is 2093:
as it travels down the concentration gradient created by removing water from the
2081:
Increasing permeability of the inner medullary portion of the collecting duct to
782: 9158: 8996: 8981: 8922: 8887: 8877: 8813: 8743: 8738: 8728: 8500: 8203: 7875: 7778: 7664: 7574: 7502: 7477: 7413: 7398: 7318: 7288: 7273: 7182: 7047: 7033: 6944: 6676: 6653: 6155: 5669: 5221: 4977: 4251:"Daily patterns of secretion of neurohypophysial hormones in man: effect of age" 4217: 3899: 3598:
National Center for Biotechnology Information, U.S. National Library of Medicine
3580:
National Center for Biotechnology Information, U.S. National Library of Medicine
3381: 2685: 2496: 2430: 2420: 2329:
synergistically with CRH to produce ACTH (by itself it is a weak secretagogue).
2242: 2145: 2071: 224: 4934:
Gutt CN, Oniu T, Mehrabi A, Schemmer P, Kashfi A, Kraus T, et al. (2004).
4531: 2061:. This occurs through increased transcription and insertion of water channels ( 1099: 9085: 9051: 9041: 9036: 9026: 8927: 8833: 8778: 8773: 8672: 8562: 8490: 8245: 8193: 8153: 8034: 8029: 8011: 7957: 7738: 7679: 7466: 7430: 7420: 7403: 7369: 7341: 7298: 6985: 6964: 6884: 6704: 6590: 6240: 6192: 6121: 6116: 5106:
Wersinger SR, Caldwell HK, Martinez L, Gold P, Hu SB, Young WS (August 2007).
4037: 3512: 3385: 3335: 3274: 3220: 3000: 2996: 2861: 2662: 2594: 2574: 2546: 2504: 1890: 915: 812: 762: 608: 432: 4006: 3770: 3247:. It is recommended that it be cautiously used in instances of perioperative 2492:
of the kidneys (especially the cortical and outer medullary collecting ducts)
21:
This article is about the natural peptide in humans. For the medication, see
9056: 9016: 8991: 8902: 8882: 8808: 8758: 8733: 8695: 8680: 8657: 8637: 8622: 8617: 8602: 8592: 8540: 8510: 8262: 8066: 7972: 7885: 7604: 7589: 7435: 7425: 7408: 7265: 7043: 6507: 6436: 6318: 6230: 6165: 6091: 5717: 3430: 3216: 3196: 3188: 3164: 2977: 2897: 2853: 2763: 2742: 2723: 2705: 2590: 2524: 2275: 2271: 2141: 2062: 1961: 1934: 1540: 1234:
cysteine-type endopeptidase inhibitor activity involved in apoptotic process
1159: 1037: 982: 969: 881: 868: 770: 312: 36: 5771: 5736: 5677: 5642: 5510: 5483: 5448: 5430: 5327: 5229: 5190: 5133: 5092: 5083: 5066: 5026: 4961: 4920: 4877: 4731: 4703: 4553:
Collège des enseignants d'endocrinologie, diabète et maladie (2012-01-30).
4539: 4368: 4333: 4235: 4186: 4137: 4096: 4055: 3946: 3911: 3884: 3866: 3835: 3778: 3086:
related to low levels of antidiuretic hormone. It is available as Pressyn.
2637:
and some related animals, whereas arginine vasopressin is found in humans.
1997:
of body fluids. It is released from the posterior pituitary in response to
7198: 5594: 5518: 5278: 5155:
Lolait SJ, Stewart LQ, Jessop DS, Young WS, O'Carroll AM (February 2007).
4936:"Circulatory and respiratory complications of carbon dioxide insufflation" 4885: 4842: 4772: 4667: 4632: 4501: 4466: 4417: 4276: 4151:
Rieg T, Tang T, Uchida S, Hammond HK, Fenton RA, Vallon V (January 2013).
3673: 3655: 1842: 1837: 9001: 8828: 8768: 8662: 8580: 8557: 8520: 8183: 8047: 7952: 7763: 7579: 7558: 7553: 7497: 6658: 6557: 6539: 6497: 6475: 6398: 6390: 6371: 6353: 6282: 6160: 6053: 6015: 5475: 5172: 4807: 3479: 3464: 3377: 3331: 3248: 3204: 3132: 3004: 2857: 2816: 2795: 2641: 2606: 2598: 2582: 2578: 2562: 2542: 2465:
secretion in response to stress; social interpretation of olfactory cues
2416: 2412: 2254: 2195: 2189: 1994: 1948:
A third function is possible. Some AVP may be released directly into the
1914: 1883: 1826: 1685: 1666: 412: 240: 4249:
Forsling ML, Montgomery H, Halpin D, Windle RJ, Treacher DF (May 1998).
4128: 4111: 2171:
Vasopressin released from posterior pituitary is associated with nausea.
421: 9130: 8986: 8912: 8798: 8552: 8383: 8299: 7895: 7880: 7870: 7860: 7813: 7783: 7624: 7609: 7229: 6989: 6562: 6529: 6524: 6516: 6403: 6338: 6209: 5967: 5656:
Young LJ (October 2009). "The neuroendocrinology of the social brain".
4763: 4746: 3296: 3288: 3042: 2849: 2802: 2719: 2610: 2602: 2570: 2448: 2390: 2293:(except in cases of AVP-secreting tumours). Vasopressin is produced by 2236: 1930: 1926: 1887: 1879: 1652: 1607: 647: 367: 219: 4952: 4935: 4614: 8818: 7890: 7818: 7545: 6686: 6648: 6467: 6408: 5586: 3434: 3356: 3327: 3200: 3192: 3176: 2959: 2692: 2630: 2550: 2541:
Chemical structure of the arginine vasopressin (argipressin) with an
2399: 2137: 2109: 1894: 1810: 1562: 512: 292: 257: 7699: 5309: 5205: 5040:
Alberts B, Bray D, Hopkin K, Johnson AD, Lewis J, Roberts K (2014).
4360: 4075:
Transactions of the American Clinical and Climatological Association
3640:"Vasopressin and oxytocin gene expression in the human hypothalamus" 4993:"The physiologic effects of pneumoperitoneum in the morbidly obese" 4110:
Knepper MA, Kim GH, Fernández-Llama P, Ecelbarger CA (March 1999).
3187:
The most common side effects during treatment with vasopressin are
2633:
in place of the arginine as the eighth amino acid, and is found in
2017:. The high-density distributions of vasopressin receptor AVPr1a in 481: 123:
Antidiuretic hormone (ADH); arginine vasopressin (AVP); argipressin
8112: 7918: 7458: 7187: 6954: 6798: 6719: 6694: 6605: 6577: 6310: 4745:
Furuya K, Shimizu R, Hirabayashi Y, Ishii R, Fukuda H (May 1993).
3208: 3172: 3008: 2931: 2556: 2536: 2457: 2403: 2395: 2218: 2214: 2014: 2003: 1949: 635: 626: 492: 288: 253: 5065:
Bielsky IF, Hu SB, Szegda KL, Westphal H, Young LJ (March 2004).
3408:
Vasopressin was elucidated and synthesized for the first time by
1525: 1521: 7119: 3757:
Babar SM (October 2013). "SIADH associated with ciprofloxacin".
3722:"Oxytocin and Vasopressin: Genetics and Behavioral Implications" 3380:(used to induce and stimulate labor), and the chemotherapy drug 3353:
Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH)
2879: 2845: 2206: 2156:
Vasopressin released within the brain may have several actions:
2082: 1902: 1326:
negative regulation of release of cytochrome c from mitochondria
750: 472: 8429: 7703: 7202: 6758: 5940: 5834: 3638:
Sukhov RR, Walker LC, Rance NE, Price DL, Young WS 3rd (1993).
3127:
patients not responding to fluid resuscitation or infusions of
3123:
Vasopressin infusions are also used as second line therapy for
7684: 5830: 5344:
Tietz Textbook of Clinical Chemistry and Molecular Diagnostics
4597:
Salata RA, Jarrett DB, Verbalis JG, Robinson AG (March 1988).
3240: 2711: 2634: 2037: 1190: 4112:"Regulation of thick ascending limb transport by vasopressin" 3355:
in turn can be caused by a number of problems. Some forms of
2654:
Comparison of vasopressin and oxytocin neuropeptide families:
3306:
vasopressor effect may be higher with the concurrent use of
537: 5936: 5378:
Scientific Foundations of Biochemistry in Clinical Practice
4202:"Molecular regulation of NKCC2 in the thick ascending limb" 98: 86: 80: 1974:
It has a very short half-life, between 16 and 24 minutes.
1411:
positive regulation of cytosolic calcium ion concentration
5415:"Molecular mechanisms of antidiuretic effect of oxytocin" 4490:
The Journal of Pharmacology and Experimental Therapeutics
4300:"What Is Nausea? A Historical Analysis of Changing Views" 1952:
from the hypothalamus, and may play an important role in
1451:
positive regulation of prostaglandin biosynthetic process
104: 5881:: DES 1-6 BOVINE NEUROPHYSIN II COMPLEX WITH VASOPRESSIN 5752:
Endocrine, Metabolic & Immune Disorders Drug Targets
3459:
Syndrome of inappropriate antidiuretic hormone secretion
3348:
Syndrome of inappropriate antidiuretic hormone secretion
3116:
in certain conditions. Use of vasopressin analogues for
2132:
The hormone vasopressin also stimulates the activity of
1913:
into the circulation in response to extracellular fluid
1006: 2549:
position. Lysine vasopressin differs only in having a
2213:. Per2 subsequently inhibits the transcription factors 1967:
Vasopressin induces differentiation of stem cells into
1406:
positive regulation of systemic arterial blood pressure
1361:
positive regulation of peptidyl-serine phosphorylation
4555:
Endocrinologie, diabétologie et maladies métaboliques
2232:
Many factors influence the secretion of vasopressin:
2120:
which aids in proper water reabsorption later in the
1171: 107: 101: 83: 74: 3731:(3rd ed.). Berlin: Springer. pp. 573–607. 2657: 2565:. Differs from AVP at only the 3rd and 8th position. 1901:, and is converted to AVP. It then travels down the 1511:
negative regulation of transmission of nerve impulse
1431:
positive regulation of cell population proliferation
95: 92: 77: 9148: 9075: 8961: 8857: 8713: 8704: 8470: 8371: 8337: 8317: 8310: 8298: 8261: 8254: 8244: 8212: 8121: 8111: 8079: 8059: 7981: 7940: 7931: 7904: 7853: 7827: 7756: 7747: 7737: 7567: 7544: 7513: 7457: 7448: 7391: 7368: 7340: 7317: 7264: 7255: 7240: 7160: 7085: 7020: 6978: 6932: 6925: 6883: 6837: 6806: 6796: 6718: 6685: 6667: 6639: 6604: 6576: 6538: 6515: 6506: 6466: 6459: 6427: 6389: 6352: 6309: 6281: 6272: 6254: 6208: 6141: 6067: 6044: 5996: 5985: 5974: 4071:"Regulation of renal urea transport by vasopressin" 1771: 1750: 1724: 1703: 646: 624: 607: 568: 563: 531: 511: 491: 471: 451: 431: 411: 400: 391: 366: 346: 321: 311: 298: 281: 271: 263: 246: 234: 218: 185: 177: 160: 152: 127: 119: 89: 65: 60: 16:
Mammalian hormone released from the pituitary gland
3554: 3552: 3550: 3533: 3531: 3529: 3108:) and in extreme cases of bedwetting by children. 2305:(SON). It then travels down the axon through the 953: 852: 380: 5606: 5604: 4200:Ares GR, Caceres PS, Ortiz PA (December 2011). 4022:"Vasopressin and the Regulation of Aquaporin-2" 2325:to the anterior pituitary, where it stimulates 355: 7675:Pituitary adenylate cyclase-activating peptide 3991:(Third ed.). Philadelphia, PA: Elsevier. 3559:GRCm38: Ensembl release 89: ENSMUSG00000037727 2922:Cys-Tyr-Ile-Asn/Gln-Asn-Cys-Pro-Leu/Val-Gly-NH 2148:channels by creating a hypo-osmotic filtrate. 2089:, which facilitates its reabsorption into the 2052:Vasopressin has three main effects which are: 1356:generation of precursor metabolites and energy 8441: 7715: 7595:Cocaine- and amphetamine-regulated transcript 7214: 6770: 5952: 5911:: BOVINE NEUROPHYSIN II COMPLEX WITH OXYTOCIN 5846: 5419:Journal of the American Society of Nephrology 4116:Journal of the American Society of Nephrology 2488:Basolateral membrane of the cells lining the 2337:Vasopressin concentration is used to measure 2209:protein accumulates and is phosphorylated by 2085:by regulating the cell surface expression of 8: 5544: 5542: 5540: 5538: 5536: 4513: 4511: 2317:of the PVN, transported and released at the 2160:Vasopressin is released into the brain in a 1456:positive regulation of cellular pH reduction 1396:G protein-coupled receptor signaling pathway 35: 3752: 3750: 3748: 3538:GRCh38: Ensembl release 89: ENSG00000101200 2257:inhibits secretion of antidiuretic hormone. 338:1-{carbonyl}-L-p rolyl-L-arginylglycinamide 8710: 8448: 8434: 8426: 8368: 8334: 8314: 8305: 8258: 8251: 8218: 8118: 8085: 7937: 7753: 7744: 7722: 7708: 7700: 7454: 7261: 7221: 7207: 7199: 6929: 6803: 6777: 6763: 6755: 6512: 6463: 6278: 5993: 5982: 5959: 5945: 5937: 5853: 5839: 5831: 5699:Mavani GP, DeVita MV, Michelis MF (2015). 4020:Wilson JL, Miranda CA, Knepper MA (2013). 2353:Types of AVP receptors and their actions: 2333:Vasopressin during surgery and anaesthesia 1536: 1506:multicellular organismal water homeostasis 1436:positive regulation of glutamate secretion 1206: 994: 893: 790: 551: 440: 32:generally, of which it is but one example. 5726: 5716: 5624: 5438: 5317: 5268: 5180: 5123: 5082: 5016: 4951: 4762: 4622: 4456: 4407: 4323: 4266: 4225: 4176: 4127: 4086: 4045: 3874: 3855:European Journal of Translational Myology 3825: 3663: 2625:-terminus of the sequence converted to a 1416:negative regulation of female receptivity 1391:regulation of signaling receptor activity 460: 5896:: UNCOMPLEXED DES 1-6 BOVINE NEUROPHYSIN 5804:(7th ed.). Philadelphia: Saunders. 5341:Burtis CA, Ashwood ER, Bruns DE (2012). 3699:. Glenview, IL: Pearson Education, Inc. 3614:Dorland's Illustrated Medical Dictionary 3223:. The most severe adverse reactions are 2629:. Lysine vasopressin (lypressin) has a 2355: 1346:negative regulation of apoptotic process 5868: 3525: 3147:Vasopressin is administered through an 2617:, with the cysteine residues forming a 2299:paraventricular nucleus of hypothalamus 2203:transcription-translation feedback loop 1971:and promotes heart muscle homeostasis. 1501:positive regulation of vasoconstriction 1110:paraventricular nucleus of hypothalamus 685: 665: 547: 420: 335: 172:paraventricular nucleus of hypothalamus 4392:"Molecular bases for circadian clocks" 4069:Sands JM, Blount MA, Klein JD (2011). 3898:Cuzzo B, Padala SA, Lappin SL (2024). 3049:Cys-Phe-Trp-Thr-Ser-Cys-Pro-Ile-Gly-NH 3031:Cys-Tyr-Phe-Arg-Asn-Cys-Pro-Ile-Gly-NH 3015:Cys-Ile-Ile-Arg-Asn-Cys-Pro-Arg-Gly-NH 2984:Cys-Phe-Ile-Arg-Asn-Cys-Pro-Lys-Gly-NH 2966:Cys-Phe-Val-Arg-Asn-Cys-Pro-Thr-Gly-NH 2948:Cys-Leu-Ile-Thr-Asn-Cys-Pro-Arg-Gly-NH 2904:Cys-Tyr-Ile-Ser-Asn-Cys-Pro-Gln-Gly-NH 2886:Cys-Tyr-Ile-Ser-Asn-Cys-Pro-Ile-Gly-NH 2868:Cys-Tyr-Ile-Gln-Ser-Cys-Pro-Ile-Gly-NH 2833:Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Ile-Gly-NH 2809:Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Pro-Gly-NH 2730:Cys-Phe-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH 2699:Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH 1366:positive regulation of gene expression 702: 34: 5464:Nephrology, Dialysis, Transplantation 5298:The Journal of Clinical Investigation 4991:Nguyen NT, Wolfe BM (February 2005). 4603:The Journal of Clinical Investigation 958: 919: 914: 857: 816: 811: 520: 500: 7: 4800:10.1001/archsurg.1978.01370170059011 4026:Clinical and Experimental Nephrology 3987:Boron WR, Boulpaep EL (2016-05-05). 2427:; social recognition, circadian tau 2321:, from which it travels through the 2315:parvocellular neurosecretory neurons 2295:magnocellular neurosecretory neurons 1964:, and maternal responses to stress. 1476:regulation of renal sodium excretion 140: 3384:. It has also been associated with 3263:- may lower the antidiuretic effect 1441:response to organic cyclic compound 480: 371: 5390:10.1016/B978-0-7506-0167-2.50010-8 5376:. In Williams DL, Marks V (eds.). 5374:"Polyuria and Disorders of Thirst" 5009:10.1097/01.sla.0000151791.93571.70 4835:10.1111/j.1365-2265.1988.tb01213.x 4648:The American Journal of Physiology 4580:Encyclopedia of Endocrine Diseases 3939:10.1016/j.neuroscience.2003.12.008 3720:Caldwell HK, Young WS III (2006). 3215:, pounding sensation in the head, 3112:and related analogues are used as 2533:Structure and relation to oxytocin 1768: 1747: 1721: 1700: 1676: 1657: 1631: 1612: 1586: 1567: 1446:positive regulation of cell growth 1176: 1094: 1032: 1011: 14: 5801:Brenner & Rector's the kidney 5764:10.2174/1871530318666180220104900 3303:may lower the antidiuretic effect 1239:neurohypophyseal hormone activity 6447:5-Methoxy-N,N-dimethyltryptamine 5916: 5901: 5886: 5871: 5613:The American Journal of Medicine 5125:10.1111/j.1601-183X.2006.00281.x 4696:10.1111/j.1532-950X.2014.12264.x 4660:10.1152/ajpregu.1990.258.6.R1516 4268:10.1113/expphysiol.1998.sp004124 4032:(6): 10.1007/s10157-013–0789-5. 3644:Journal of Comparative Neurology 3475:Vasopressin receptor antagonists 3398:vasopressin receptor antagonists 3195:, chest pain, abdominal cramps, 2112:absorption across the ascending 1285:clathrin-coated vesicle membrane 1254:V1B vasopressin receptor binding 1249:V1A vasopressin receptor binding 1180: 942: 935: 929: 906: 841: 834: 828: 803: 711: 586: 580: 70: 52: 43: 7585:Calcitonin gene-related peptide 5658:Frontiers in Neuroendocrinology 5499:Frontiers in Neuroendocrinology 4751:Canadian Journal of Anaesthesia 3334:(excess urine production), and 3308:ganglionic blocking medications 2103:outer medullary collecting duct 693:Key:KBZOIRJILGZLEJ-LGYYRGKSSA-N 7968:Norepinephrine (noradrenaline) 7168:Fractional excretion of sodium 5798:Rector FC, Brenner BM (2004). 4866:The British Journal of Surgery 3359:can cause SIADH, particularly 3093:and ventricular fibrillation. 1939:peripheral vascular resistance 1481:hyperosmotic salinity response 1191:More reference expression data 1160:More reference expression data 598: 592: 574: 1: 9214:Vasopressin receptor agonists 5270:10.1182/blood.V86.7.2760.2760 4458:10.1016/s0092-8674(00)80959-9 4409:10.1016/s0092-8674(00)80566-8 4206:Am. J. Physiol. Renal Physiol 3759:The Annals of Pharmacotherapy 3727:. In Lajtha A, Lim R (eds.). 3366:serotonin reuptake inhibitors 3285:may raise the diuretic effect 2118:countercurrent multiplication 1259:neuropeptide hormone activity 927: 826: 9199:Posterior pituitary hormones 9189:Genes on human chromosome 20 7600:Delta-sleep-inducing peptide 5635:10.1016/j.amjmed.2007.09.001 4316:10.1016/j.autneu.2016.07.003 4169:10.1016/j.ajpath.2012.09.014 3970:"Central Diabetes Insipidus" 3818:10.1016/j.neuron.2010.03.005 2419:aggregation, and release of 2194:Vasopressin is regulated by 1401:maternal aggressive behavior 7146:Effective renal plasma flow 6990:Intracellular fluid/Cytosol 5670:10.1016/j.yfrne.2009.06.002 5222:10.1016/j.yhbeh.2004.07.004 4218:10.1152/ajprenal.00396.2011 3617:(32nd ed.). Elsevier. 2463:Adrenocorticotropic hormone 2036:, has the same function in 1993:Vasopressin regulates the 1134:nucleus of stria terminalis 9250: 7095:Glomerular filtration rate 7087:Assessment and measurement 6950:Atrial natriuretic peptide 6615:Insulin-like growth factor 5555:. F.A. Davis Company. 2017 4532:10.1152/ajpregu.00324.2010 4390:Dunlap JC (January 1999). 3495:Atrial natriuretic peptide 3345: 3219:, sweating, paleness, and 3075: 2775:Vertebrate Oxytocin Family 2523:"-vaptan" diuretics, i.e. 2503:and surface expression of 2402:, peripheral vasculature, 2249:Atrial natriuretic peptide 2187: 2024:A very similar substance, 1981: 1351:protein kinase C signaling 1244:signaling receptor binding 564:Chemical and physical data 27: 20: 9017:Vasotocin (argiprestocin) 9012:Vasopressin (argipressin) 8903:Vasotocin (argiprestocin) 8898:Vasopressin (argipressin) 8759:Vasotocin (argiprestocin) 8754:Vasopressin (argipressin) 8541:Vasotocin (argiprestocin) 8221: 8088: 7774:Glutamic acid (glutamate) 7769:Aspartic acid (aspartate) 7620:Gastrin-releasing peptide 7178:Tubuloglomerular feedback 7105:Augmented renal clearance 7062:Bicarbonate buffer system 6786:Physiology of the kidneys 5866: 5112:Genes, Brain and Behavior 4038:10.1007/s10157-013-0789-5 3906:. StatPearls Publishing. 3900:"Physiology, Vasopressin" 3594:"Mouse PubMed Reference:" 3576:"Human PubMed Reference:" 3439:major depressive disorder 3370:tricyclic antidepressants 3361:small cell lung carcinoma 3279:tricyclic antidepressants 3175:and excreted through the 3064: 2995:Geography & imperial 2937: 2773: 2660: 2323:hypophyseal portal system 2291:posterior pituitary gland 1933:. Second, AVP constricts 1925:from the filtrate in the 1841: 1836: 1832: 1825: 1809: 1803:Chr 2: 130.42 – 130.42 Mb 1790: 1775: 1754: 1743: 1728: 1707: 1696: 1683: 1679: 1664: 1660: 1651: 1638: 1634: 1619: 1615: 1606: 1593: 1589: 1574: 1570: 1561: 1546: 1539: 1535: 1519: 1209: 1205: 1188: 1179: 1170: 1157: 1106: 1097: 1044: 1035: 1005: 997: 993: 976: 963: 926: 905: 896: 892: 875: 862: 825: 802: 793: 789: 744: 741: 731: 724: 719: 710: 705: 676: 656: 326: 51: 42: 7958:Epinephrine (adrenaline) 7067:Respiratory compensation 6824:Clearance of medications 5349:Elsevier Health Sciences 3771:10.1177/1060028013502457 3697:Anatomy & physiology 3501:Renin-angiotensin system 3322:, a condition featuring 3171:. It is degraded by the 3078:Vasopressin (medication) 2270:, (such as can occur in 2262:Production and secretion 2099:cortical collecting duct 1461:response to testosterone 1052:internal globus pallidus 28:Not to be confused with 23:Vasopressin (medication) 7173:BUN-to-creatinine ratio 6908:Countercurrent exchange 5718:10.3389/fmed.2015.00019 5071:Neuropsychopharmacology 4720:Medical Science Monitor 4255:Experimental Physiology 3800:Insel TR (March 2010). 3153:intramuscular injection 3091:ventricular tachycardia 2363:Second messenger system 2166:suprachiasmatic nucleus 1909:, and is released from 1371:renal water homeostasis 1224:protein kinase activity 1130:suprachiasmatic nucleus 8933:ORG-52186 (SCH-740935) 8655:Catabolism inhibitors: 8393:Carbonyl sulfide (COS) 7994:N-Methylphenethylamine 7670:Pancreatic polypeptide 6442:N,N-Dimethyltryptamine 6419:Pancreatic polypeptide 5511:10.1006/frne.1995.1009 5431:10.1681/ASN.2007010029 5084:10.1038/sj.npp.1300360 5042:Essential Cell Biology 4878:10.1002/bjs.1800721215 4823:Clinical Endocrinology 3976:. Merck & Co. Inc. 3867:10.4081/bam.2014.3.217 3429:Vasopressin has shown 3372:), the anticonvulsant 3157:subcutaneous injection 3102:von Willebrand disease 2566: 2561:Chemical structure of 2554: 2507:through exocytosis of 2152:Central nervous system 2091:medullary interstitium 1796:Chr 20: 3.08 – 3.08 Mb 8134:2-AGE (noladin ether) 7110:Renal clearance ratio 7029:Darrow Yannet diagram 5705:Frontiers in Medicine 5619:(11 Suppl 1): S1–21. 5382:Butterworth-Heinemann 5210:Hormones and Behavior 3656:10.1002/cne.903370210 3225:myocardial infarction 2844:Most marsupials, all 2647:magnocellular neurons 2569:The vasopressins are 2560: 2540: 2501:von Willebrand factor 2425:von Willebrand factor 2188:Further information: 1982:Further information: 1882:synthesized from the 1386:membrane organization 1331:ERK1 and ERK2 cascade 819:Chromosome 20 (human) 287:Predominantly in the 252:Predominantly in the 8461:vasopressin receptor 8345:Carbon monoxide (CO) 7615:Galanin-like peptide 7135:Hemodialysis product 7115:Urea reduction ratio 7100:Creatinine clearance 6940:Antidiuretic hormone 6790:acid–base physiology 5372:Donaldson D (1994). 5173:10.1210/en.2006-1309 4654:(6 Pt 2): R1516-20. 4298:Magtanong E (2017). 3611:Anderson DA (2012). 3470:Vasopressin receptor 2827:northern tree shrews 2509:Weibel-Palade bodies 2445:Phosphatidylinositol 2387:Phosphatidylinositol 1941:and raises arterial 1868:arginine vasopressin 1860:antidiuretic hormone 1466:response to nicotine 1275:extracellular region 1142:lateral hypothalamus 1138:ventromedial nucleus 1084:right adrenal cortex 960:2 F1|2 63.24 cM 921:Chromosome 2 (mouse) 8663:Bestatin (ubenimex) 8350:Hydrogen sulfide (H 8204:Virodhamine (O-AEA) 7011:Transcellular fluid 6995:Extracellular fluid 6913:Filtration fraction 6728:Natriuretic peptide 6046:Posterior pituitary 6031:Somatostatin (GHIH) 5384:. pp. 76–102. 5044:. Garland Science. 4788:Archives of Surgery 4557:. Elsevier Masson. 4349:Nature Neuroscience 4129:10.1681/ASN.V103628 3410:Vincent du Vigneaud 3169:extracellular fluid 3120:commenced in 1970. 3026:Striped cone snail 2573:consisting of nine 2327:corticotropic cells 2116:. This adds to the 1907:posterior pituitary 1905:terminating in the 1496:response to ethanol 1426:locomotory behavior 1376:signal transduction 1341:cell-cell signaling 1290:extracellular space 39: 9204:Neuroendocrinology 8407:Sulfur dioxide (SO 8318:Cholinergic system 8020:Phenylethanolamine 7999:N-Methyltryptamine 7963:NAS (normelatonin) 7750:inhibitory systems 7748:Major excitatory / 7072:Renal compensation 7001:Interstitial fluid 6069:Anterior pituitary 5476:10.1093/ndt/gfh413 4764:10.1007/BF03009513 4684:Veterinary Surgery 3989:Medical Physiology 3485:Anterior pituitary 3320:diabetes insipidus 3213:water intoxication 3161:duration of action 3149:intravenous device 3118:esophageal varices 3084:diabetes insipidus 2665:Vasopressin Family 2567: 2555: 2303:supraoptic nucleus 2164:by neurons of the 2108:Acute increase of 2026:lysine vasopressin 1937:, which increases 1641:ENSMUSG00000037727 1309:Biological process 1268:Cellular component 1217:Molecular function 1114:supraoptic nucleus 1080:anterior pituitary 168:Supraoptic nucleus 9176: 9175: 9156:Carrier proteins: 9144: 9143: 9135:lithium carbonate 9123:Other inhibitors: 8675: 8531:PF-06655075 (PF1) 8423: 8422: 8419: 8418: 8367: 8366: 8359:Nitric oxide (NO) 8333: 8332: 8306: 8294: 8293: 8290: 8289: 8240: 8239: 8236: 8235: 8107: 8106: 8103: 8102: 8075: 8074: 7989:3-Iodothyronamine 7927: 7926: 7731:Neurotransmitters 7697: 7696: 7693: 7692: 7444: 7443: 7196: 7195: 7130:Dialysis adequacy 7125:Standardized Kt/V 7081: 7080: 7039:Davenport diagram 7022:Acid–base balance 6921: 6920: 6898:Renal plasma flow 6752: 6751: 6748: 6747: 6635: 6634: 6455: 6454: 6385: 6384: 6137: 6136: 5934: 5933: 5811:978-0-7216-0164-9 5399:978-0-7506-0167-2 5358:978-1-4557-5942-2 5051:978-0-8153-4455-1 4997:Annals of Surgery 4953:10.1159/000077038 4940:Digestive Surgery 4757:(5 Pt 1): 435–9. 4615:10.1172/JCI113382 4564:978-2-294-72233-2 3998:978-1-4557-4377-3 3738:978-0-387-30348-2 3706:978-0-321-86158-0 3695:Marieb E (2014). 3624:978-1-4160-6257-8 3507:Bainbridge reflex 3326:(increased blood 3235:Contraindications 3069: 3068: 2942:VP/OT Superfamily 2823:New World monkeys 2785:-Gln-Asn-Cys-Pro- 2753:-Gln-Asn-Cys-Pro- 2675:-Gln-Asn-Cys-Pro- 2640:The structure of 2553:in this position. 2530: 2529: 2513:endothelial cells 2480:Adenylate cyclase 2095:connecting tubule 2087:urea transporters 1958:sexual motivation 1852: 1851: 1848: 1847: 1821: 1820: 1786: 1785: 1765: 1764: 1739: 1738: 1718: 1717: 1692: 1691: 1673: 1672: 1647: 1646: 1628: 1627: 1602: 1601: 1583: 1582: 1531: 1530: 1486:maternal behavior 1421:grooming behavior 1381:apoptotic process 1295:secretory granule 1201: 1200: 1197: 1196: 1166: 1165: 1153: 1152: 1091: 1090: 989: 988: 888: 887: 701: 700: 652:1.6±0.1 g/cm 637:Interactive image 533:CompTox Dashboard 9241: 9209:Renal physiology 8711: 8686:o-Phenanthroline 8673: 8450: 8443: 8436: 8427: 8398:Nitrous oxide (N 8369: 8338:Gasotransmitters 8335: 8315: 8259: 8252: 8219: 8154:Anandamide (AEA) 8122:Endocannabinoids 8119: 8086: 7973:Serotonin (5-HT) 7938: 7757:Glutamate system 7754: 7745: 7724: 7717: 7710: 7701: 7455: 7262: 7223: 7216: 7209: 7200: 7151:Extraction ratio 7054:Winters' formula 6930: 6893:Renal blood flow 6819:Pharmacokinetics 6804: 6779: 6772: 6765: 6756: 6513: 6508:Digestive system 6464: 6279: 6218:Thyroid hormones 5994: 5983: 5961: 5954: 5947: 5938: 5920: 5905: 5890: 5875: 5855: 5848: 5841: 5832: 5826: 5824: 5823: 5814:. Archived from 5784: 5783: 5747: 5741: 5740: 5730: 5720: 5696: 5690: 5689: 5653: 5647: 5646: 5628: 5608: 5599: 5598: 5587:10.1148/98.3.497 5570: 5564: 5563: 5561: 5560: 5554: 5546: 5531: 5530: 5494: 5488: 5487: 5459: 5453: 5452: 5442: 5410: 5404: 5403: 5380:(2nd ed.). 5369: 5363: 5362: 5351:. p. 1833. 5347:(5th ed.). 5338: 5332: 5331: 5321: 5289: 5283: 5282: 5272: 5248: 5242: 5241: 5201: 5195: 5194: 5184: 5152: 5146: 5145: 5127: 5103: 5097: 5096: 5086: 5062: 5056: 5055: 5037: 5031: 5030: 5020: 4988: 4982: 4981: 4955: 4931: 4925: 4924: 4904: 4898: 4897: 4861: 4855: 4854: 4818: 4812: 4811: 4783: 4777: 4776: 4766: 4742: 4736: 4735: 4714: 4708: 4707: 4678: 4672: 4671: 4643: 4637: 4636: 4626: 4594: 4588: 4587: 4575: 4569: 4568: 4550: 4544: 4543: 4515: 4506: 4505: 4485: 4479: 4478: 4460: 4436: 4430: 4429: 4411: 4387: 4381: 4380: 4344: 4338: 4337: 4327: 4295: 4289: 4288: 4270: 4246: 4240: 4239: 4229: 4197: 4191: 4190: 4180: 4148: 4142: 4141: 4131: 4107: 4101: 4100: 4090: 4066: 4060: 4059: 4049: 4017: 4011: 4010: 3984: 3978: 3977: 3965: 3959: 3958: 3922: 3916: 3915: 3895: 3889: 3888: 3878: 3846: 3840: 3839: 3829: 3797: 3791: 3790: 3754: 3743: 3742: 3726: 3717: 3711: 3710: 3692: 3686: 3685: 3667: 3635: 3629: 3628: 3608: 3602: 3601: 3590: 3584: 3583: 3572: 3566: 3556: 3545: 3535: 3443:bipolar disorder 3386:fluoroquinolones 3330:concentration), 3229:hypersensitivity 3143:Pharmacokinetics 3114:vasoconstrictors 3022:Arg-Connopressin 2991:Lys-Connopressin 2658: 2490:collecting ducts 2409:Vasoconstriction 2356: 2162:circadian rhythm 2008:vasoconstriction 1984:Renal physiology 1834: 1833: 1805: 1798: 1781: 1769: 1760: 1748: 1744:RefSeq (protein) 1734: 1722: 1713: 1701: 1677: 1658: 1632: 1613: 1587: 1568: 1537: 1321:vasoconstriction 1229:hormone activity 1207: 1193: 1184: 1177: 1162: 1102: 1100:Top expressed in 1095: 1040: 1038:Top expressed in 1033: 1012: 995: 985: 972: 961: 946: 939: 933: 922: 910: 894: 884: 871: 860: 845: 838: 832: 821: 807: 791: 785: 736: 729: 715: 703: 639: 619: 617: 600: 594: 588: 582: 576: 556: 555: 541: 539: 524: 504: 484: 464: 444: 424: 404: 384: 374: 373: 359: 303: 144: 114: 113: 110: 109: 106: 103: 100: 97: 94: 91: 88: 85: 82: 79: 76: 56: 47: 40: 38: 9249: 9248: 9244: 9243: 9242: 9240: 9239: 9238: 9234:Stress hormones 9179: 9178: 9177: 9172: 9140: 9071: 8966: 8957: 8862: 8853: 8718: 8700: 8506:Lipo-oxytocin-1 8466: 8454: 8424: 8415: 8410: 8401: 8387: 8363: 8353: 8329: 8286: 8232: 8208: 8099: 8071: 8055: 7977: 7933:Biogenic amines 7923: 7900: 7849: 7823: 7749: 7733: 7728: 7698: 7689: 7645:Neuropeptide VF 7640:Neuropeptide SF 7635:Neuropeptide FF 7630:Neuropeptide AF 7563: 7540: 7509: 7450: 7440: 7387: 7364: 7336: 7313: 7282: 7257:Opioid peptides 7251: 7236: 7227: 7197: 7192: 7156: 7077: 7016: 6974: 6926:Other functions 6917: 6903:Ultrafiltration 6879: 6833: 6829:Urine flow rate 6792: 6783: 6753: 6744: 6714: 6681: 6663: 6631: 6600: 6572: 6534: 6502: 6451: 6423: 6381: 6348: 6305: 6268: 6250: 6234: 6226: 6204: 6188:Adrenal medulla 6181:Androstenedione 6133: 6063: 6040: 5988: 5977: 5970: 5965: 5935: 5930: 5927: 5921: 5912: 5906: 5897: 5891: 5882: 5876: 5862: 5859: 5829: 5821: 5819: 5812: 5797: 5793: 5791:Further reading 5788: 5787: 5749: 5748: 5744: 5698: 5697: 5693: 5655: 5654: 5650: 5626:10.1.1.499.7585 5610: 5609: 5602: 5572: 5571: 5567: 5558: 5556: 5552: 5548: 5547: 5534: 5496: 5495: 5491: 5461: 5460: 5456: 5412: 5411: 5407: 5400: 5371: 5370: 5366: 5359: 5340: 5339: 5335: 5310:10.1172/JCI9516 5291: 5290: 5286: 5250: 5249: 5245: 5203: 5202: 5198: 5154: 5153: 5149: 5105: 5104: 5100: 5064: 5063: 5059: 5052: 5039: 5038: 5034: 4990: 4989: 4985: 4933: 4932: 4928: 4906: 4905: 4901: 4863: 4862: 4858: 4820: 4819: 4815: 4785: 4784: 4780: 4744: 4743: 4739: 4726:(9): CR445-52. 4716: 4715: 4711: 4680: 4679: 4675: 4645: 4644: 4640: 4596: 4595: 4591: 4577: 4576: 4572: 4565: 4552: 4551: 4547: 4517: 4516: 4509: 4487: 4486: 4482: 4438: 4437: 4433: 4389: 4388: 4384: 4361:10.1038/nn.2987 4346: 4345: 4341: 4297: 4296: 4292: 4248: 4247: 4243: 4212:(6): F1143–59. 4199: 4198: 4194: 4150: 4149: 4145: 4109: 4108: 4104: 4068: 4067: 4063: 4019: 4018: 4014: 3999: 3986: 3985: 3981: 3967: 3966: 3962: 3924: 3923: 3919: 3897: 3896: 3892: 3848: 3847: 3843: 3799: 3798: 3794: 3765:(10): 1359–63. 3756: 3755: 3746: 3739: 3724: 3719: 3718: 3714: 3707: 3694: 3693: 3689: 3637: 3636: 3632: 3625: 3610: 3609: 3605: 3592: 3591: 3587: 3574: 3573: 3569: 3557: 3548: 3536: 3527: 3522: 3455: 3427: 3418: 3406: 3350: 3344: 3316: 3283:fludrocortisone 3271:chloropropamide 3257: 3237: 3185: 3145: 3080: 3074: 3052: 3034: 3018: 2987: 2969: 2951: 2925: 2907: 2889: 2871: 2836: 2812: 2792: 2760: 2733: 2702: 2682: 2616: 2535: 2454:Pituitary gland 2440:AVPR1B or AVPR3 2351: 2343:noxious stimuli 2339:surgical stress 2335: 2319:median eminence 2264: 2229:gene products. 2192: 2186: 2184:Gene regulation 2181: 2154: 2126:collecting duct 2067:apical membrane 2050: 1991: 1986: 1980: 1954:social behavior 1919:hyperosmolality 1843:View/Edit Mouse 1838:View/Edit Human 1801: 1794: 1791:Location (UCSC) 1777: 1756: 1730: 1709: 1622:ENSG00000101200 1515: 1491:penile erection 1471:social behavior 1336:water transport 1304: 1263: 1189: 1158: 1149: 1144: 1140: 1136: 1132: 1128: 1126:median eminence 1124: 1120: 1118:arcuate nucleus 1116: 1112: 1098: 1087: 1082: 1078: 1074: 1070: 1066: 1062: 1058: 1054: 1050: 1036: 980: 967: 959: 949: 948: 947: 940: 920: 897:Gene location ( 879: 866: 858: 848: 847: 846: 839: 817: 794:Gene location ( 783:AVP - orthologs 745: 732: 725: 697: 694: 689: 684: 683: 672: 669: 664: 663: 642: 615: 613: 603: 597: 591: 585: 579: 559: 535: 527: 507: 487: 467: 447: 427: 407: 387: 370: 362: 342: 339: 334: 333: 301: 273:Protein binding 265:Pharmacokinetic 209: 202: 195: 148: 73: 69: 33: 26: 17: 12: 11: 5: 9247: 9245: 9237: 9236: 9231: 9226: 9221: 9216: 9211: 9206: 9201: 9196: 9191: 9181: 9180: 9174: 9173: 9171: 9170: 9152: 9150: 9146: 9145: 9142: 9141: 9139: 9138: 9128: 9126:Demeclocycline 9119: 9118: 9113: 9108: 9103: 9098: 9093: 9088: 9079: 9077: 9073: 9072: 9070: 9069: 9064: 9059: 9054: 9049: 9044: 9039: 9034: 9029: 9020: 9019: 9014: 9009: 9004: 8999: 8994: 8989: 8984: 8979: 8970: 8968: 8964: 8959: 8958: 8956: 8955: 8946: 8945: 8940: 8935: 8930: 8925: 8920: 8915: 8906: 8905: 8900: 8895: 8890: 8885: 8880: 8875: 8866: 8864: 8860: 8855: 8854: 8852: 8851: 8846: 8841: 8836: 8831: 8826: 8821: 8816: 8811: 8806: 8801: 8796: 8791: 8786: 8781: 8776: 8771: 8762: 8761: 8756: 8751: 8746: 8741: 8736: 8731: 8722: 8720: 8716: 8708: 8702: 8701: 8699: 8698: 8693: 8691:Phosphoramidon 8688: 8683: 8678: 8670: 8665: 8660: 8651: 8650: 8645: 8640: 8635: 8630: 8625: 8620: 8615: 8610: 8605: 8600: 8595: 8583: 8571: 8570: 8565: 8560: 8555: 8550: 8538: 8533: 8528: 8523: 8518: 8513: 8508: 8503: 8498: 8493: 8488: 8476: 8474: 8468: 8467: 8455: 8453: 8452: 8445: 8438: 8430: 8421: 8420: 8417: 8416: 8414: 8413: 8408: 8404: 8399: 8395: 8390: 8385: 8381: 8375: 8373: 8365: 8364: 8362: 8361: 8356: 8351: 8347: 8341: 8339: 8331: 8330: 8328: 8327: 8321: 8319: 8312: 8308: 8307: 8303: 8296: 8295: 8292: 8291: 8288: 8287: 8285: 8284: 8279: 8274: 8268: 8266: 8256: 8249: 8242: 8241: 8238: 8237: 8234: 8233: 8231: 8230: 8222: 8216: 8210: 8209: 8207: 8206: 8201: 8196: 8191: 8186: 8181: 8176: 8171: 8166: 8161: 8156: 8151: 8146: 8141: 8136: 8131: 8125: 8123: 8116: 8109: 8108: 8105: 8104: 8101: 8100: 8098: 8097: 8089: 8083: 8077: 8076: 8073: 8072: 8070: 8069: 8063: 8061: 8057: 8056: 8054: 8053: 8045: 8037: 8032: 8027: 8025:Phenethylamine 8022: 8017: 8009: 8001: 7996: 7991: 7985: 7983: 7979: 7978: 7976: 7975: 7970: 7965: 7960: 7955: 7950: 7944: 7942: 7935: 7929: 7928: 7925: 7924: 7922: 7921: 7916: 7910: 7908: 7902: 7901: 7899: 7898: 7893: 7888: 7883: 7878: 7873: 7868: 7863: 7857: 7855: 7854:Glycine system 7851: 7850: 7848: 7847: 7842: 7837: 7831: 7829: 7825: 7824: 7822: 7821: 7816: 7811: 7806: 7801: 7799:Kynurenic acid 7796: 7791: 7786: 7781: 7776: 7771: 7766: 7760: 7758: 7751: 7742: 7735: 7734: 7729: 7727: 7726: 7719: 7712: 7704: 7695: 7694: 7691: 7690: 7688: 7687: 7682: 7677: 7672: 7667: 7662: 7657: 7655:Neuropeptide Y 7652: 7650:Neuropeptide S 7647: 7642: 7637: 7632: 7627: 7622: 7617: 7612: 7607: 7602: 7597: 7592: 7587: 7582: 7577: 7571: 7569: 7565: 7564: 7562: 7561: 7556: 7550: 7548: 7542: 7541: 7539: 7538: 7533: 7528: 7523: 7517: 7515: 7511: 7510: 7508: 7507: 7506: 7505: 7500: 7492: 7491: 7490: 7485: 7480: 7469: 7463: 7461: 7452: 7446: 7445: 7442: 7441: 7439: 7438: 7433: 7428: 7423: 7418: 7417: 7416: 7406: 7401: 7395: 7393: 7389: 7388: 7386: 7385: 7383:Leu-enkephalin 7380: 7378:Met-enkephalin 7374: 7372: 7366: 7365: 7363: 7362: 7357: 7352: 7346: 7344: 7338: 7337: 7335: 7334: 7329: 7323: 7321: 7315: 7314: 7312: 7311: 7309:β-Neoendorphin 7306: 7304:α-Neoendorphin 7301: 7296: 7291: 7286: 7285: 7284: 7280: 7270: 7268: 7259: 7253: 7252: 7244: 7242: 7238: 7237: 7228: 7226: 7225: 7218: 7211: 7203: 7194: 7193: 7191: 7190: 7185: 7180: 7175: 7170: 7164: 7162: 7158: 7157: 7155: 7154: 7148: 7139: 7138: 7137: 7127: 7122: 7117: 7112: 7107: 7102: 7097: 7091: 7089: 7083: 7082: 7079: 7078: 7076: 7075: 7074: 7069: 7064: 7056: 7051: 7041: 7036: 7031: 7026: 7024: 7018: 7017: 7015: 7014: 7008: 7003: 6997: 6984: 6982: 6976: 6975: 6973: 6972: 6970:Prostaglandins 6967: 6962: 6960:Erythropoietin 6957: 6952: 6947: 6942: 6936: 6934: 6927: 6923: 6922: 6919: 6918: 6916: 6915: 6910: 6905: 6900: 6895: 6889: 6887: 6881: 6880: 6878: 6877: 6872: 6867: 6862: 6857: 6852: 6847: 6841: 6839: 6835: 6834: 6832: 6831: 6826: 6821: 6816: 6810: 6808: 6801: 6794: 6793: 6784: 6782: 6781: 6774: 6767: 6759: 6750: 6749: 6746: 6745: 6743: 6742: 6741: 6740: 6735: 6724: 6722: 6716: 6715: 6713: 6712: 6707: 6702: 6697: 6691: 6689: 6683: 6682: 6680: 6679: 6673: 6671: 6665: 6664: 6662: 6661: 6656: 6651: 6645: 6643: 6641:Adipose tissue 6637: 6636: 6633: 6632: 6630: 6629: 6628: 6627: 6622: 6611: 6609: 6602: 6601: 6599: 6598: 6593: 6588: 6586:Enteroglucagon 6582: 6580: 6574: 6573: 6571: 6570: 6565: 6560: 6555: 6550: 6544: 6542: 6536: 6535: 6533: 6532: 6527: 6521: 6519: 6510: 6504: 6503: 6501: 6500: 6495: 6490: 6489: 6488: 6486:Beta thymosins 6483: 6472: 6470: 6461: 6457: 6456: 6453: 6452: 6450: 6449: 6444: 6439: 6433: 6431: 6425: 6424: 6422: 6421: 6416: 6411: 6406: 6401: 6395: 6393: 6387: 6386: 6383: 6382: 6380: 6379: 6374: 6369: 6364: 6358: 6356: 6350: 6349: 6347: 6346: 6341: 6336: 6331: 6326: 6321: 6315: 6313: 6307: 6306: 6304: 6303: 6298: 6293: 6287: 6285: 6276: 6270: 6269: 6267: 6266: 6260: 6258: 6252: 6251: 6249: 6248: 6243: 6238: 6237: 6236: 6232: 6228: 6224: 6214: 6212: 6206: 6205: 6203: 6202: 6201: 6200: 6198:Norepinephrine 6195: 6185: 6184: 6183: 6178: 6173: 6168: 6163: 6158: 6151:Adrenal cortex 6147: 6145: 6139: 6138: 6135: 6134: 6132: 6131: 6126: 6125: 6124: 6119: 6114: 6109: 6104: 6094: 6089: 6084: 6079: 6073: 6071: 6065: 6064: 6062: 6061: 6056: 6050: 6048: 6042: 6041: 6039: 6038: 6033: 6028: 6023: 6018: 6013: 6008: 6002: 6000: 5991: 5980: 5972: 5971: 5966: 5964: 5963: 5956: 5949: 5941: 5932: 5931: 5929: 5928: 5922: 5915: 5913: 5907: 5900: 5898: 5892: 5885: 5883: 5877: 5870: 5867: 5864: 5863: 5860: 5858: 5857: 5850: 5843: 5835: 5828: 5827: 5810: 5794: 5792: 5789: 5786: 5785: 5758:(4): 341–347. 5742: 5691: 5648: 5600: 5581:(3): 497–505. 5565: 5532: 5489: 5470:(10): 2480–6. 5454: 5405: 5398: 5364: 5357: 5333: 5284: 5243: 5196: 5147: 5098: 5057: 5050: 5032: 5003:(2): 219–226. 4983: 4926: 4899: 4872:(12): 979–82. 4856: 4813: 4794:(5): 597–600. 4778: 4737: 4709: 4673: 4638: 4589: 4570: 4563: 4545: 4507: 4480: 4431: 4382: 4355:(12): 1496–7. 4339: 4304:Auton Neurosci 4290: 4241: 4192: 4143: 4102: 4061: 4012: 3997: 3979: 3960: 3917: 3890: 3841: 3792: 3744: 3737: 3712: 3705: 3687: 3650:(2): 295–306. 3630: 3623: 3603: 3585: 3567: 3546: 3524: 3523: 3521: 3518: 3517: 3516: 3510: 3504: 3498: 3492: 3487: 3482: 3477: 3472: 3467: 3462: 3454: 3451: 3426: 3423: 3417: 3416:Animal studies 3414: 3405: 3402: 3346:Main article: 3343: 3340: 3315: 3312: 3311: 3310: 3304: 3301:norepinephrine 3293:demeclocycline 3286: 3264: 3256: 3253: 3245:kidney failure 3236: 3233: 3184: 3181: 3144: 3141: 3137:norepinephrine 3129:catecholamines 3076:Main article: 3073: 3070: 3067: 3066: 3062: 3061: 3058: 3053: 3050: 3046: 3045: 3040: 3035: 3032: 3028: 3027: 3024: 3019: 3016: 3012: 3011: 2993: 2988: 2985: 2981: 2980: 2975: 2970: 2967: 2963: 2962: 2957: 2952: 2949: 2945: 2944: 2935: 2934: 2929: 2928:Various tocins 2926: 2923: 2919: 2918: 2913: 2908: 2905: 2901: 2900: 2895: 2890: 2887: 2883: 2882: 2877: 2872: 2869: 2865: 2864: 2842: 2837: 2834: 2830: 2829: 2819: 2813: 2810: 2806: 2805: 2801:Most mammals, 2799: 2793: 2790: 2778: 2777: 2771: 2770: 2767: 2761: 2758: 2746: 2745: 2739: 2734: 2731: 2727: 2726: 2709: 2703: 2700: 2696: 2695: 2689: 2683: 2680: 2668: 2667: 2619:disulfide bond 2614: 2534: 2531: 2528: 2527: 2521: 2515: 2493: 2486: 2477: 2471: 2470: 2468: 2466: 2460: 2451: 2442: 2436: 2435: 2433: 2428: 2406: 2393: 2384: 2378: 2377: 2374: 2371: 2368: 2365: 2360: 2350: 2347: 2334: 2331: 2263: 2260: 2259: 2258: 2252: 2246: 2240: 2185: 2182: 2180: 2177: 2176: 2175: 2172: 2169: 2153: 2150: 2130: 2129: 2106: 2079: 2049: 2046: 1990: 1987: 1979: 1976: 1969:cardiomyocytes 1943:blood pressure 1927:kidney tubules 1858:, also called 1850: 1849: 1846: 1845: 1840: 1830: 1829: 1823: 1822: 1819: 1818: 1816: 1814: 1807: 1806: 1799: 1792: 1788: 1787: 1784: 1783: 1773: 1772: 1766: 1763: 1762: 1752: 1751: 1745: 1741: 1740: 1737: 1736: 1726: 1725: 1719: 1716: 1715: 1705: 1704: 1698: 1694: 1693: 1690: 1689: 1681: 1680: 1674: 1671: 1670: 1662: 1661: 1655: 1649: 1648: 1645: 1644: 1636: 1635: 1629: 1626: 1625: 1617: 1616: 1610: 1604: 1603: 1600: 1599: 1591: 1590: 1584: 1581: 1580: 1572: 1571: 1565: 1559: 1558: 1553: 1548: 1544: 1543: 1533: 1532: 1529: 1528: 1517: 1516: 1514: 1513: 1508: 1503: 1498: 1493: 1488: 1483: 1478: 1473: 1468: 1463: 1458: 1453: 1448: 1443: 1438: 1433: 1428: 1423: 1418: 1413: 1408: 1403: 1398: 1393: 1388: 1383: 1378: 1373: 1368: 1363: 1358: 1353: 1348: 1343: 1338: 1333: 1328: 1323: 1318: 1312: 1310: 1306: 1305: 1303: 1302: 1297: 1292: 1287: 1282: 1277: 1271: 1269: 1265: 1264: 1262: 1261: 1256: 1251: 1246: 1241: 1236: 1231: 1226: 1220: 1218: 1214: 1213: 1203: 1202: 1199: 1198: 1195: 1194: 1186: 1185: 1174: 1168: 1167: 1164: 1163: 1155: 1154: 1151: 1150: 1148: 1147: 1143: 1139: 1135: 1131: 1127: 1123: 1119: 1115: 1111: 1107: 1104: 1103: 1092: 1089: 1088: 1086: 1085: 1081: 1077: 1073: 1069: 1065: 1061: 1057: 1056:gastric mucosa 1053: 1049: 1045: 1042: 1041: 1029: 1028: 1020: 1009: 1003: 1002: 999:RNA expression 991: 990: 987: 986: 978: 974: 973: 965: 962: 957: 951: 950: 941: 934: 928: 924: 923: 918: 912: 911: 903: 902: 890: 889: 886: 885: 877: 873: 872: 864: 861: 856: 850: 849: 840: 833: 827: 823: 822: 815: 809: 808: 800: 799: 787: 786: 743: 739: 738: 730: 722: 721: 717: 716: 708: 707: 699: 698: 696: 695: 692: 690: 687: 679: 678: 677: 674: 673: 671: 670: 667: 659: 658: 657: 654: 653: 650: 644: 643: 641: 640: 632: 630: 622: 621: 611: 605: 604: 601: 595: 589: 583: 577: 572: 566: 565: 561: 560: 558: 557: 544: 542: 529: 528: 526: 525: 517: 515: 509: 508: 506: 505: 497: 495: 489: 488: 486: 485: 477: 475: 469: 468: 466: 465: 457: 455: 449: 448: 446: 445: 437: 435: 429: 428: 426: 425: 417: 415: 409: 408: 406: 405: 397: 395: 389: 388: 386: 385: 377: 375: 364: 363: 361: 360: 352: 350: 344: 343: 341: 340: 337: 329: 328: 327: 324: 323: 319: 318: 315: 309: 308: 305: 296: 295: 285: 279: 278: 275: 269: 268: 261: 260: 250: 244: 243: 238: 232: 231: 222: 216: 215: 207: 200: 193: 189: 183: 182: 179: 178:Target tissues 175: 174: 165: 158: 157: 150: 149: 147: 146: 133: 131: 125: 124: 121: 117: 116: 67: 63: 62: 58: 57: 49: 48: 15: 13: 10: 9: 6: 4: 3: 2: 9246: 9235: 9232: 9230: 9227: 9225: 9224:Antidiuretics 9222: 9220: 9217: 9215: 9212: 9210: 9207: 9205: 9202: 9200: 9197: 9195: 9194:Neuropeptides 9192: 9190: 9187: 9186: 9184: 9168: 9164: 9160: 9157: 9154: 9153: 9151: 9147: 9136: 9132: 9129: 9127: 9124: 9121: 9120: 9117: 9114: 9112: 9109: 9107: 9104: 9102: 9099: 9097: 9094: 9092: 9089: 9087: 9084: 9081: 9080: 9078: 9074: 9068: 9065: 9063: 9060: 9058: 9055: 9053: 9050: 9048: 9045: 9043: 9040: 9038: 9035: 9033: 9030: 9028: 9025: 9022: 9021: 9018: 9015: 9013: 9010: 9008: 9005: 9003: 9000: 8998: 8995: 8993: 8990: 8988: 8985: 8983: 8980: 8978: 8975: 8972: 8971: 8969: 8967: 8960: 8954: 8951: 8948: 8947: 8944: 8941: 8939: 8936: 8934: 8931: 8929: 8926: 8924: 8921: 8919: 8916: 8914: 8911: 8908: 8907: 8904: 8901: 8899: 8896: 8894: 8891: 8889: 8886: 8884: 8881: 8879: 8876: 8874: 8871: 8868: 8867: 8865: 8863: 8856: 8850: 8847: 8845: 8842: 8840: 8837: 8835: 8832: 8830: 8827: 8825: 8822: 8820: 8817: 8815: 8812: 8810: 8807: 8805: 8802: 8800: 8797: 8795: 8792: 8790: 8787: 8785: 8782: 8780: 8777: 8775: 8772: 8770: 8767: 8764: 8763: 8760: 8757: 8755: 8752: 8750: 8747: 8745: 8742: 8740: 8737: 8735: 8732: 8730: 8727: 8724: 8723: 8721: 8719: 8712: 8709: 8707: 8703: 8697: 8694: 8692: 8689: 8687: 8684: 8682: 8679: 8677: 8671: 8669: 8666: 8664: 8661: 8659: 8656: 8653: 8652: 8649: 8646: 8644: 8641: 8639: 8636: 8634: 8631: 8629: 8626: 8624: 8621: 8619: 8616: 8614: 8611: 8609: 8606: 8604: 8601: 8599: 8596: 8594: 8591: 8587: 8586:Tocinoic acid 8584: 8582: 8579: 8576: 8573: 8572: 8569: 8566: 8564: 8561: 8559: 8556: 8554: 8551: 8549: 8546: 8542: 8539: 8537: 8534: 8532: 8529: 8527: 8524: 8522: 8519: 8517: 8514: 8512: 8509: 8507: 8504: 8502: 8499: 8497: 8494: 8492: 8489: 8487: 8484: 8481: 8478: 8477: 8475: 8473: 8469: 8465: 8462: 8458: 8451: 8446: 8444: 8439: 8437: 8432: 8431: 8428: 8412: 8405: 8403: 8396: 8394: 8391: 8389: 8382: 8380: 8377: 8376: 8374: 8370: 8360: 8357: 8355: 8348: 8346: 8343: 8342: 8340: 8336: 8326: 8325:Acetylcholine 8323: 8322: 8320: 8316: 8313: 8311:Miscellaneous 8309: 8304: 8301: 8297: 8283: 8280: 8278: 8275: 8273: 8270: 8269: 8267: 8264: 8260: 8257: 8253: 8250: 8247: 8243: 8228: 8224: 8223: 8220: 8217: 8215: 8214:Neurosteroids 8211: 8205: 8202: 8200: 8197: 8195: 8192: 8190: 8187: 8185: 8182: 8180: 8177: 8175: 8172: 8170: 8167: 8165: 8162: 8160: 8157: 8155: 8152: 8150: 8147: 8145: 8142: 8140: 8137: 8135: 8132: 8130: 8127: 8126: 8124: 8120: 8117: 8114: 8110: 8095: 8091: 8090: 8087: 8084: 8082: 8081:Neuropeptides 8078: 8068: 8065: 8064: 8062: 8058: 8052: 8050: 8046: 8044: 8042: 8038: 8036: 8033: 8031: 8028: 8026: 8023: 8021: 8018: 8016: 8014: 8010: 8008: 8006: 8002: 8000: 7997: 7995: 7992: 7990: 7987: 7986: 7984: 7980: 7974: 7971: 7969: 7966: 7964: 7961: 7959: 7956: 7954: 7951: 7949: 7946: 7945: 7943: 7939: 7936: 7934: 7930: 7920: 7917: 7915: 7912: 7911: 7909: 7907: 7903: 7897: 7894: 7892: 7889: 7887: 7884: 7882: 7879: 7877: 7874: 7872: 7869: 7867: 7864: 7862: 7859: 7858: 7856: 7852: 7846: 7843: 7841: 7838: 7836: 7833: 7832: 7830: 7826: 7820: 7817: 7815: 7812: 7810: 7807: 7805: 7802: 7800: 7797: 7795: 7792: 7790: 7787: 7785: 7782: 7780: 7777: 7775: 7772: 7770: 7767: 7765: 7762: 7761: 7759: 7755: 7752: 7746: 7743: 7740: 7736: 7732: 7725: 7720: 7718: 7713: 7711: 7706: 7705: 7702: 7686: 7683: 7681: 7678: 7676: 7673: 7671: 7668: 7666: 7663: 7661: 7658: 7656: 7653: 7651: 7648: 7646: 7643: 7641: 7638: 7636: 7633: 7631: 7628: 7626: 7623: 7621: 7618: 7616: 7613: 7611: 7608: 7606: 7603: 7601: 7598: 7596: 7593: 7591: 7588: 7586: 7583: 7581: 7578: 7576: 7573: 7572: 7570: 7566: 7560: 7557: 7555: 7552: 7551: 7549: 7547: 7543: 7537: 7534: 7532: 7529: 7527: 7524: 7522: 7519: 7518: 7516: 7512: 7504: 7501: 7499: 7496: 7495: 7493: 7489: 7486: 7484: 7481: 7479: 7476: 7475: 7473: 7470: 7468: 7465: 7464: 7462: 7460: 7456: 7453: 7451:neuropeptides 7447: 7437: 7434: 7432: 7429: 7427: 7424: 7422: 7419: 7415: 7412: 7411: 7410: 7407: 7405: 7402: 7400: 7397: 7396: 7394: 7390: 7384: 7381: 7379: 7376: 7375: 7373: 7371: 7367: 7361: 7358: 7356: 7353: 7351: 7348: 7347: 7345: 7343: 7339: 7333: 7332:Endomorphin-2 7330: 7328: 7327:Endomorphin-1 7325: 7324: 7322: 7320: 7316: 7310: 7307: 7305: 7302: 7300: 7297: 7295: 7294:Big dynorphin 7292: 7290: 7287: 7283: 7277: 7276: 7275: 7272: 7271: 7269: 7267: 7263: 7260: 7258: 7254: 7250: 7249: 7243: 7239: 7235: 7234:neuropeptides 7231: 7224: 7219: 7217: 7212: 7210: 7205: 7204: 7201: 7189: 7186: 7184: 7181: 7179: 7176: 7174: 7171: 7169: 7166: 7165: 7163: 7159: 7152: 7149: 7147: 7143: 7142:PAH clearance 7140: 7136: 7133: 7132: 7131: 7128: 7126: 7123: 7121: 7118: 7116: 7113: 7111: 7108: 7106: 7103: 7101: 7098: 7096: 7093: 7092: 7090: 7088: 7084: 7073: 7070: 7068: 7065: 7063: 7060: 7059: 7057: 7055: 7052: 7049: 7045: 7042: 7040: 7037: 7035: 7032: 7030: 7027: 7025: 7023: 7019: 7012: 7009: 7007: 7004: 7002: 6998: 6996: 6993: 6992: 6991: 6987: 6983: 6981: 6980:Fluid balance 6977: 6971: 6968: 6966: 6963: 6961: 6958: 6956: 6953: 6951: 6948: 6946: 6943: 6941: 6938: 6937: 6935: 6931: 6928: 6924: 6914: 6911: 6909: 6906: 6904: 6901: 6899: 6896: 6894: 6891: 6890: 6888: 6886: 6882: 6876: 6873: 6871: 6870:Oligopeptides 6868: 6866: 6863: 6861: 6858: 6856: 6853: 6851: 6848: 6846: 6843: 6842: 6840: 6836: 6830: 6827: 6825: 6822: 6820: 6817: 6815: 6812: 6811: 6809: 6805: 6802: 6800: 6795: 6791: 6787: 6780: 6775: 6773: 6768: 6766: 6761: 6760: 6757: 6739: 6736: 6734: 6731: 6730: 6729: 6726: 6725: 6723: 6721: 6717: 6711: 6710:Prostaglandin 6708: 6706: 6703: 6701: 6698: 6696: 6693: 6692: 6690: 6688: 6684: 6678: 6675: 6674: 6672: 6670: 6666: 6660: 6657: 6655: 6652: 6650: 6647: 6646: 6644: 6642: 6638: 6626: 6623: 6621: 6618: 6617: 6616: 6613: 6612: 6610: 6607: 6603: 6597: 6594: 6592: 6589: 6587: 6584: 6583: 6581: 6579: 6575: 6569: 6566: 6564: 6561: 6559: 6556: 6554: 6551: 6549: 6546: 6545: 6543: 6541: 6537: 6531: 6528: 6526: 6523: 6522: 6520: 6518: 6514: 6511: 6509: 6505: 6499: 6496: 6494: 6491: 6487: 6484: 6482: 6479: 6478: 6477: 6474: 6473: 6471: 6469: 6465: 6462: 6458: 6448: 6445: 6443: 6440: 6438: 6435: 6434: 6432: 6430: 6426: 6420: 6417: 6415: 6412: 6410: 6407: 6405: 6402: 6400: 6397: 6396: 6394: 6392: 6388: 6378: 6375: 6373: 6370: 6368: 6365: 6363: 6360: 6359: 6357: 6355: 6351: 6345: 6342: 6340: 6337: 6335: 6332: 6330: 6327: 6325: 6322: 6320: 6317: 6316: 6314: 6312: 6308: 6302: 6299: 6297: 6294: 6292: 6289: 6288: 6286: 6284: 6280: 6277: 6275: 6271: 6265: 6262: 6261: 6259: 6257: 6253: 6247: 6244: 6242: 6239: 6235: 6229: 6227: 6221: 6220: 6219: 6216: 6215: 6213: 6211: 6207: 6199: 6196: 6194: 6191: 6190: 6189: 6186: 6182: 6179: 6177: 6174: 6172: 6169: 6167: 6164: 6162: 6159: 6157: 6154: 6153: 6152: 6149: 6148: 6146: 6144: 6140: 6130: 6127: 6123: 6120: 6118: 6115: 6113: 6110: 6108: 6105: 6103: 6100: 6099: 6098: 6095: 6093: 6090: 6088: 6085: 6083: 6080: 6078: 6075: 6074: 6072: 6070: 6066: 6060: 6057: 6055: 6052: 6051: 6049: 6047: 6043: 6037: 6034: 6032: 6029: 6027: 6024: 6022: 6019: 6017: 6014: 6012: 6009: 6007: 6004: 6003: 6001: 5999: 5995: 5992: 5990: 5987:Hypothalamic– 5984: 5981: 5979: 5973: 5969: 5962: 5957: 5955: 5950: 5948: 5943: 5942: 5939: 5925: 5919: 5914: 5910: 5904: 5899: 5895: 5889: 5884: 5880: 5874: 5869: 5865: 5856: 5851: 5849: 5844: 5842: 5837: 5836: 5833: 5818:on 2016-03-03 5817: 5813: 5807: 5803: 5802: 5796: 5795: 5790: 5781: 5777: 5773: 5769: 5765: 5761: 5757: 5753: 5746: 5743: 5738: 5734: 5729: 5724: 5719: 5714: 5710: 5706: 5702: 5695: 5692: 5687: 5683: 5679: 5675: 5671: 5667: 5663: 5659: 5652: 5649: 5644: 5640: 5636: 5632: 5627: 5622: 5618: 5614: 5607: 5605: 5601: 5596: 5592: 5588: 5584: 5580: 5576: 5569: 5566: 5551: 5550:"Vasopressin" 5545: 5543: 5541: 5539: 5537: 5533: 5528: 5524: 5520: 5516: 5512: 5508: 5505:(3): 237–89. 5504: 5500: 5493: 5490: 5485: 5481: 5477: 5473: 5469: 5465: 5458: 5455: 5450: 5446: 5441: 5436: 5432: 5428: 5425:(2): 225–32. 5424: 5420: 5416: 5409: 5406: 5401: 5395: 5391: 5387: 5383: 5379: 5375: 5368: 5365: 5360: 5354: 5350: 5346: 5345: 5337: 5334: 5329: 5325: 5320: 5315: 5311: 5307: 5304:(1): 107–16. 5303: 5299: 5295: 5288: 5285: 5280: 5276: 5271: 5266: 5263:(7): 2760–6. 5262: 5258: 5254: 5247: 5244: 5239: 5235: 5231: 5227: 5223: 5219: 5216:(5): 638–45. 5215: 5211: 5207: 5200: 5197: 5192: 5188: 5183: 5178: 5174: 5170: 5167:(2): 849–56. 5166: 5162: 5161:Endocrinology 5158: 5151: 5148: 5143: 5139: 5135: 5131: 5126: 5121: 5118:(6): 540–51. 5117: 5113: 5109: 5102: 5099: 5094: 5090: 5085: 5080: 5077:(3): 483–93. 5076: 5072: 5068: 5061: 5058: 5053: 5047: 5043: 5036: 5033: 5028: 5024: 5019: 5014: 5010: 5006: 5002: 4998: 4994: 4987: 4984: 4979: 4975: 4971: 4967: 4963: 4959: 4954: 4949: 4946:(2): 95–105. 4945: 4941: 4937: 4930: 4927: 4922: 4918: 4914: 4910: 4903: 4900: 4895: 4891: 4887: 4883: 4879: 4875: 4871: 4867: 4860: 4857: 4852: 4848: 4844: 4840: 4836: 4832: 4829:(3): 277–82. 4828: 4824: 4817: 4814: 4809: 4805: 4801: 4797: 4793: 4789: 4782: 4779: 4774: 4770: 4765: 4760: 4756: 4752: 4748: 4741: 4738: 4733: 4729: 4725: 4721: 4713: 4710: 4705: 4701: 4697: 4693: 4689: 4685: 4677: 4674: 4669: 4665: 4661: 4657: 4653: 4649: 4642: 4639: 4634: 4630: 4625: 4620: 4616: 4612: 4609:(3): 766–74. 4608: 4604: 4600: 4593: 4590: 4586:(2): 969–974. 4585: 4581: 4574: 4571: 4566: 4560: 4556: 4549: 4546: 4541: 4537: 4533: 4529: 4526:(3): R624–9. 4525: 4521: 4514: 4512: 4508: 4503: 4499: 4496:(2): 705–11. 4495: 4491: 4484: 4481: 4476: 4472: 4468: 4464: 4459: 4454: 4450: 4446: 4442: 4435: 4432: 4427: 4423: 4419: 4415: 4410: 4405: 4402:(2): 271–90. 4401: 4397: 4393: 4386: 4383: 4378: 4374: 4370: 4366: 4362: 4358: 4354: 4350: 4343: 4340: 4335: 4331: 4326: 4321: 4317: 4313: 4309: 4305: 4301: 4294: 4291: 4286: 4282: 4278: 4274: 4269: 4264: 4261:(3): 409–18. 4260: 4256: 4252: 4245: 4242: 4237: 4233: 4228: 4223: 4219: 4215: 4211: 4207: 4203: 4196: 4193: 4188: 4184: 4179: 4174: 4170: 4166: 4163:(1): 96–106. 4162: 4158: 4157:Am. J. Pathol 4154: 4147: 4144: 4139: 4135: 4130: 4125: 4122:(3): 628–34. 4121: 4117: 4113: 4106: 4103: 4098: 4094: 4089: 4084: 4080: 4076: 4072: 4065: 4062: 4057: 4053: 4048: 4043: 4039: 4035: 4031: 4027: 4023: 4016: 4013: 4008: 4004: 4000: 3994: 3990: 3983: 3980: 3975: 3971: 3964: 3961: 3956: 3952: 3948: 3944: 3940: 3936: 3932: 3928: 3921: 3918: 3913: 3909: 3905: 3901: 3894: 3891: 3886: 3882: 3877: 3872: 3868: 3864: 3860: 3856: 3852: 3845: 3842: 3837: 3833: 3828: 3823: 3819: 3815: 3812:(6): 768–79. 3811: 3807: 3803: 3796: 3793: 3788: 3784: 3780: 3776: 3772: 3768: 3764: 3760: 3753: 3751: 3749: 3745: 3740: 3734: 3730: 3723: 3716: 3713: 3708: 3702: 3698: 3691: 3688: 3683: 3679: 3675: 3671: 3666: 3661: 3657: 3653: 3649: 3645: 3641: 3634: 3631: 3626: 3620: 3616: 3615: 3607: 3604: 3599: 3595: 3589: 3586: 3581: 3577: 3571: 3568: 3564: 3560: 3555: 3553: 3551: 3547: 3543: 3539: 3534: 3532: 3530: 3526: 3519: 3514: 3511: 3508: 3505: 3502: 3499: 3496: 3493: 3491: 3488: 3486: 3483: 3481: 3478: 3476: 3473: 3471: 3468: 3466: 3463: 3460: 3457: 3456: 3452: 3450: 3448: 3447:schizophrenia 3444: 3440: 3436: 3432: 3425:Human studies 3424: 3422: 3415: 3413: 3411: 3403: 3401: 3399: 3395: 3391: 3390:ciprofloxacin 3387: 3383: 3379: 3375: 3374:carbamazepine 3371: 3367: 3362: 3358: 3354: 3349: 3341: 3339: 3337: 3333: 3329: 3325: 3324:hypernatremia 3321: 3313: 3309: 3305: 3302: 3298: 3294: 3290: 3287: 3284: 3280: 3276: 3272: 3268: 3267:carbamazepine 3265: 3262: 3259: 3258: 3254: 3252: 3250: 3246: 3242: 3234: 3232: 3230: 3226: 3222: 3218: 3214: 3210: 3207:, trembling, 3206: 3202: 3198: 3194: 3190: 3182: 3180: 3178: 3174: 3170: 3166: 3162: 3158: 3154: 3150: 3142: 3140: 3138: 3134: 3130: 3126: 3121: 3119: 3115: 3111: 3107: 3106:haemophilia A 3103: 3099: 3094: 3092: 3087: 3085: 3079: 3071: 3063: 3059: 3057: 3054: 3048: 3047: 3044: 3041: 3039: 3036: 3030: 3029: 3025: 3023: 3020: 3014: 3013: 3010: 3006: 3002: 2998: 2994: 2992: 2989: 2983: 2982: 2979: 2976: 2974: 2971: 2965: 2964: 2961: 2958: 2956: 2953: 2947: 2946: 2943: 2941: 2936: 2933: 2930: 2927: 2921: 2920: 2917: 2914: 2912: 2909: 2903: 2902: 2899: 2896: 2894: 2891: 2885: 2884: 2881: 2878: 2876: 2873: 2867: 2866: 2863: 2859: 2855: 2851: 2847: 2843: 2841: 2838: 2832: 2831: 2828: 2824: 2820: 2818: 2814: 2808: 2807: 2804: 2800: 2797: 2794: 2788: 2784: 2780: 2779: 2776: 2772: 2768: 2765: 2762: 2756: 2752: 2748: 2747: 2744: 2740: 2738: 2735: 2729: 2728: 2725: 2721: 2717: 2713: 2710: 2707: 2704: 2698: 2697: 2694: 2690: 2687: 2684: 2678: 2674: 2670: 2669: 2666: 2664: 2659: 2656: 2655: 2651: 2648: 2643: 2638: 2636: 2632: 2628: 2627:primary amide 2624: 2620: 2612: 2608: 2604: 2600: 2596: 2592: 2588: 2584: 2580: 2576: 2572: 2564: 2559: 2552: 2548: 2544: 2539: 2532: 2526: 2522: 2520: 2516: 2514: 2510: 2506: 2502: 2498: 2495:Insertion of 2494: 2491: 2487: 2485: 2481: 2478: 2476: 2473: 2472: 2469: 2467: 2464: 2461: 2459: 2455: 2452: 2450: 2446: 2443: 2441: 2438: 2437: 2434: 2432: 2429: 2426: 2422: 2418: 2414: 2410: 2407: 2405: 2401: 2397: 2394: 2392: 2388: 2385: 2383: 2380: 2379: 2375: 2372: 2369: 2366: 2364: 2361: 2358: 2357: 2354: 2348: 2346: 2344: 2340: 2332: 2330: 2328: 2324: 2320: 2316: 2311: 2308: 2304: 2300: 2296: 2292: 2287: 2285: 2284:baroreceptors 2281: 2280:heart failure 2277: 2273: 2269: 2261: 2256: 2253: 2250: 2247: 2244: 2241: 2238: 2235: 2234: 2233: 2230: 2228: 2224: 2220: 2216: 2212: 2208: 2204: 2200: 2198: 2191: 2183: 2178: 2173: 2170: 2167: 2163: 2159: 2158: 2157: 2151: 2149: 2147: 2143: 2139: 2135: 2127: 2123: 2122:distal tubule 2119: 2115: 2114:loop of Henle 2111: 2107: 2104: 2100: 2096: 2092: 2088: 2084: 2080: 2077: 2073: 2068: 2064: 2060: 2055: 2054: 2053: 2047: 2045: 2043: 2039: 2035: 2031: 2027: 2022: 2020: 2016: 2011: 2009: 2005: 2000: 1999:hypertonicity 1996: 1988: 1985: 1977: 1975: 1972: 1970: 1965: 1963: 1959: 1955: 1951: 1946: 1944: 1940: 1936: 1932: 1928: 1924: 1920: 1916: 1915:hypertonicity 1912: 1908: 1904: 1900: 1896: 1892: 1889: 1885: 1881: 1877: 1873: 1869: 1865: 1861: 1857: 1844: 1839: 1835: 1831: 1828: 1824: 1817: 1815: 1812: 1808: 1804: 1800: 1797: 1793: 1789: 1782: 1780: 1774: 1770: 1767: 1761: 1759: 1753: 1749: 1746: 1742: 1735: 1733: 1727: 1723: 1720: 1714: 1712: 1706: 1702: 1699: 1697:RefSeq (mRNA) 1695: 1688: 1687: 1682: 1678: 1675: 1669: 1668: 1663: 1659: 1656: 1654: 1650: 1643: 1642: 1637: 1633: 1630: 1624: 1623: 1618: 1614: 1611: 1609: 1605: 1598: 1597: 1592: 1588: 1585: 1579: 1578: 1573: 1569: 1566: 1564: 1560: 1557: 1554: 1552: 1549: 1545: 1542: 1538: 1534: 1527: 1523: 1518: 1512: 1509: 1507: 1504: 1502: 1499: 1497: 1494: 1492: 1489: 1487: 1484: 1482: 1479: 1477: 1474: 1472: 1469: 1467: 1464: 1462: 1459: 1457: 1454: 1452: 1449: 1447: 1444: 1442: 1439: 1437: 1434: 1432: 1429: 1427: 1424: 1422: 1419: 1417: 1414: 1412: 1409: 1407: 1404: 1402: 1399: 1397: 1394: 1392: 1389: 1387: 1384: 1382: 1379: 1377: 1374: 1372: 1369: 1367: 1364: 1362: 1359: 1357: 1354: 1352: 1349: 1347: 1344: 1342: 1339: 1337: 1334: 1332: 1329: 1327: 1324: 1322: 1319: 1317: 1314: 1313: 1311: 1308: 1307: 1301: 1298: 1296: 1293: 1291: 1288: 1286: 1283: 1281: 1278: 1276: 1273: 1272: 1270: 1267: 1266: 1260: 1257: 1255: 1252: 1250: 1247: 1245: 1242: 1240: 1237: 1235: 1232: 1230: 1227: 1225: 1222: 1221: 1219: 1216: 1215: 1212: 1211:Gene ontology 1208: 1204: 1192: 1187: 1183: 1178: 1175: 1173: 1169: 1161: 1156: 1145: 1141: 1137: 1133: 1129: 1125: 1121: 1117: 1113: 1109: 1108: 1105: 1101: 1096: 1093: 1083: 1079: 1075: 1071: 1067: 1063: 1060:apex of heart 1059: 1055: 1051: 1047: 1046: 1043: 1039: 1034: 1031: 1030: 1027: 1025: 1021: 1019: 1018: 1014: 1013: 1010: 1008: 1004: 1000: 996: 992: 984: 979: 975: 971: 966: 956: 952: 945: 938: 932: 925: 917: 913: 909: 904: 900: 895: 891: 883: 878: 874: 870: 865: 855: 851: 844: 837: 831: 824: 820: 814: 810: 806: 801: 797: 792: 788: 784: 780: 776: 772: 768: 764: 760: 756: 752: 748: 740: 735: 728: 723: 718: 714: 709: 704: 691: 686: 682: 675: 666: 662: 655: 651: 649: 645: 638: 634: 633: 631: 628: 623: 612: 610: 606: 573: 571: 567: 562: 554: 550: 549:DTXSID0048349 546: 545: 543: 534: 530: 523: 519: 518: 516: 514: 510: 503: 499: 498: 496: 494: 490: 483: 479: 478: 476: 474: 470: 463: 459: 458: 456: 454: 450: 443: 439: 438: 436: 434: 430: 423: 419: 418: 416: 414: 410: 403: 399: 398: 396: 394: 390: 383: 379: 378: 376: 369: 365: 358: 354: 353: 351: 349: 345: 336: 332: 325: 320: 316: 314: 310: 307:10–20 minutes 306: 304: 297: 294: 290: 286: 284: 280: 276: 274: 270: 266: 262: 259: 255: 251: 249: 245: 242: 239: 237: 233: 230: 226: 223: 221: 217: 214: 210: 203: 196: 190: 188: 184: 180: 176: 173: 169: 166: 164: 159: 155: 154:Physiological 151: 143: 138: 135: 134: 132: 130: 126: 122: 118: 112: 68: 66:Pronunciation 64: 61:Clinical data 59: 55: 50: 46: 41: 31: 24: 19: 9229:Nonapeptides 9155: 9122: 9083:Antagonists: 9082: 9032:JNJ-17079166 9024:Antagonists: 9023: 9011: 9007:Terlipressin 8977:Desmopressin 8973: 8949: 8943:TASP-0390325 8938:TASP-0233278 8910:Antagonists: 8909: 8897: 8893:Terlipressin 8873:Desmopressin 8869: 8794:JNJ-17308616 8789:JNJ-17079166 8766:Antagonists: 8765: 8753: 8749:Terlipressin 8725: 8654: 8590:Non-peptide: 8589: 8577: 8575:Antagonists: 8574: 8545:Non-peptide: 8544: 8482: 8479: 8379:Acetaldehyde 8048: 8040: 8012: 8004: 7982:Trace amines 7660:Neurophysins 7488:Neurokinin B 7483:Neurokinin A 7319:Endomorphins 7245: 6939: 6845:Solvent drag 6838:Reabsorption 6493:Thymopoietin 6429:Pineal gland 6414:Somatostatin 6377:Progesterone 6324:Progesterone 6291:Testosterone 6274:Gonadal axis 6246:Thyroid axis 6143:Adrenal axis 6058: 5998:Hypothalamus 5923: 5908: 5893: 5878: 5820:. Retrieved 5816:the original 5800: 5755: 5751: 5745: 5708: 5704: 5694: 5664:(4): 425–8. 5661: 5657: 5651: 5616: 5612: 5578: 5574: 5568: 5557:. Retrieved 5502: 5498: 5492: 5467: 5463: 5457: 5422: 5418: 5408: 5377: 5367: 5343: 5336: 5301: 5297: 5287: 5260: 5256: 5246: 5213: 5209: 5199: 5164: 5160: 5150: 5115: 5111: 5101: 5074: 5070: 5060: 5041: 5035: 5000: 4996: 4986: 4943: 4939: 4929: 4912: 4908: 4902: 4869: 4865: 4859: 4826: 4822: 4816: 4791: 4787: 4781: 4754: 4750: 4740: 4723: 4719: 4712: 4690:(7): 852–9. 4687: 4683: 4676: 4651: 4647: 4641: 4606: 4602: 4592: 4583: 4579: 4573: 4554: 4548: 4523: 4519: 4493: 4489: 4483: 4451:(1): 57–68. 4448: 4444: 4434: 4399: 4395: 4385: 4352: 4348: 4342: 4307: 4303: 4293: 4258: 4254: 4244: 4209: 4205: 4195: 4160: 4156: 4146: 4119: 4115: 4105: 4078: 4074: 4064: 4029: 4025: 4015: 3988: 3982: 3973: 3963: 3933:(1): 35–45. 3930: 3927:Neuroscience 3926: 3920: 3903: 3893: 3858: 3854: 3844: 3809: 3805: 3795: 3762: 3758: 3728: 3715: 3696: 3690: 3647: 3643: 3633: 3613: 3606: 3597: 3588: 3579: 3570: 3490:Hypothalamus 3428: 3419: 3407: 3394:moxifloxacin 3351: 3317: 3255:Interactions 3243:and chronic 3238: 3186: 3183:Side effects 3146: 3125:septic shock 3122: 3110:Terlipressin 3104:and in mild 3098:desmopressin 3095: 3088: 3081: 3038:Cephalotocin 2940:Invertebrate 2938: 2786: 2782: 2774: 2769:Non-mammals 2754: 2750: 2737:Phenypressin 2676: 2672: 2661: 2653: 2652: 2639: 2622: 2568: 2519:desmopressin 2376:Antagonists 2352: 2336: 2312: 2307:infundibulum 2288: 2268:blood volume 2265: 2231: 2226: 2222: 2196: 2193: 2155: 2131: 2072:V2 receptors 2059:antidiuresis 2051: 2042:desmopressin 2033: 2029: 2025: 2023: 2019:prairie vole 2012: 1992: 1973: 1966: 1962:pair bonding 1947: 1899:hypothalamus 1875: 1871: 1867: 1863: 1859: 1855: 1853: 1776: 1755: 1729: 1708: 1684: 1665: 1639: 1620: 1594: 1575: 1555: 1550: 1064:human kidney 1048:hypothalamus 1022: 1015: 981:130,424,474 968:130,422,540 742:External IDs 522:ChEMBL373742 300:Elimination 229:desmopressin 30:vasopressors 18: 9159:Neurophysin 8997:Ornipressin 8982:Felypressin 8923:Brezivaptan 8888:Ornipressin 8878:Felypressin 8814:Relcovaptan 8744:Selepressin 8739:Ornipressin 8729:Felypressin 8706:Vasopressin 8676:-Methionine 8526:PF-06478939 8501:Demoxytocin 8384:Ammonia (NH 8255:Nucleosides 8015:-Octopamine 8007:-Octopamine 7919:T-HCA (GHC) 7876:Hypotaurine 7828:GABA system 7779:Glutathione 7665:Neurotensin 7575:Angiotensin 7514:Neuromedins 7503:Physalaemin 7478:Substance P 7472:Tachykinins 7467:Bradykinins 7414:Hemorphin-4 7399:Adrenorphin 7370:Enkephalins 7360:γ-Endorphin 7355:β-Endorphin 7350:α-Endorphin 7289:Dynorphin B 7279:Dynorphin A 7274:Dynorphin A 7183:Natriuresis 7048:Delta ratio 7034:Base excess 6945:Aldosterone 6677:Osteocalcin 6654:Adiponectin 6481:Thymosin α1 6256:Parathyroid 6156:Aldosterone 6059:Vasopressin 5861:PDB gallery 3861:(3): 3790. 3388:(including 3382:vincristine 3072:Medical use 3056:Octopressin 2898:Bony fishes 2862:coelacanths 2686:Argipressin 2575:amino acids 2545:at the 8th 2497:aquaporin-2 2431:Felypressin 2421:factor VIII 2415:breakdown, 2243:Angiotensin 2146:aquaporin 2 2065:) into the 2063:Aquaporin-2 1923:circulation 1876:argipressin 1856:vasopressin 1122:optic nerve 1072:left testis 720:Identifiers 620: g·mol 322:Identifiers 236:Antagonists 225:Felypressin 181:System-wide 120:Other names 37:Vasopressin 9183:Categories 9096:RWJ-339489 9091:Ribuvaptan 9086:Balovaptan 9052:Satavaptan 9047:RWJ-351647 9042:Mozavaptan 9037:Lixivaptan 9027:Conivaptan 8928:Nelivaptan 8834:WAY-267464 8779:Conivaptan 8774:Balovaptan 8648:WAY-162720 8643:SSR-126768 8598:Cligosiban 8563:WAY-267464 8516:Nacartocin 8496:Cargutocin 8491:Carbetocin 8486:Aspartocin 8464:modulators 8372:Candidates 8246:Nucleobase 8035:Tryptamine 8030:Synephrine 7941:Monoamines 7906:GHB system 7739:Amino acid 7494:amphibian 7431:Spinorphin 7421:Nociceptin 7404:Amidorphin 7342:Endorphins 7299:Leumorphin 7266:Dynorphins 7058:Buffering 6986:Body water 6965:Calcitriol 6885:Filtration 6705:Calcitriol 6591:Peptide YY 6241:Calcitonin 6193:Adrenaline 6122:Lipotropin 6117:Endorphins 5822:2008-12-08 5559:2017-03-13 4915:: 99–108. 3904:StatPearls 3853:. review. 3565:, May 2017 3544:, May 2017 3520:References 3513:Baroreflex 3338:(thirst). 3336:polydipsia 3314:Deficiency 3275:clofibrate 3221:flatulence 3001:pond snail 2997:cone snail 2911:Glumitocin 2858:lungfishes 2854:amphibians 2743:marsupials 2724:marsupials 2688:(AVP, ADH) 2663:Vertebrate 2547:amino acid 2505:P-selectin 2301:(PVN) and 2179:Regulation 1978:Physiology 1935:arterioles 1891:prohormone 1026:(ortholog) 880:3,084,724 867:3,082,556 763:HomoloGene 625:3D model ( 609:Molar mass 502:CHEBI:9937 462:Y87Y826H08 433:ChemSpider 393:IUPHAR/BPS 357:11000-17-2 348:CAS Number 331:IUPAC name 283:Metabolism 248:Metabolism 9116:YM-222546 9057:Tolvaptan 8992:Lypressin 8974:Agonists: 8883:Lypressin 8870:Agonists: 8809:PF-184563 8804:LY-307174 8784:FR-218944 8734:Lypressin 8726:Agonists: 8696:Puromycin 8681:Leupeptin 8658:Amastatin 8638:Retosiban 8633:Nolasiban 8628:L-372,662 8623:L-371,257 8618:L-368,899 8608:Erlosiban 8603:Epelsiban 8593:Barusiban 8511:Merotocin 8480:Agonists: 8263:Adenosine 8067:Histamine 8051:-Tyramine 8043:-Tyramine 7886:Sarcosine 7866:β-Alanine 7861:α-Alanine 7605:FMRFamide 7590:Carnosine 7474:: mammal 7436:Valorphin 7426:Opiorphin 7409:Hemorphin 7044:Anion gap 6814:Clearance 6807:Secretion 6797:Creating 6476:Thymosins 6437:Melatonin 6319:Estradiol 6166:Cortisone 6092:Prolactin 5989:pituitary 5976:Endocrine 5621:CiteSeerX 5575:Radiology 4978:223606053 4377:205434100 4081:: 82–92. 4007:951680737 3431:nootropic 3217:diarrhoea 3197:heartburn 3189:dizziness 3165:half life 2978:Earthworm 2973:Annetocin 2875:Seritocin 2840:Mesotocin 2764:Vasotocin 2706:Lypressin 2525:tolvaptan 2373:Agonists 2367:Locations 2349:Receptors 2276:nephrosis 2272:cirrhosis 2142:threonine 2034:lypressin 1779:NP_033862 1758:NP_000481 1732:NM_009732 1711:NM_000490 1541:Orthologs 771:GeneCards 313:Excretion 302:half-life 241:Diuretics 187:Receptors 9111:VMAX-382 9106:VMAX-372 9101:VMAX-367 9076:Unsorted 9067:YM-35471 9002:TC OT 39 8953:TASP-699 8950:Ligands: 8849:YM-35471 8829:TC OT 39 8769:Atosiban 8581:Atosiban 8578:Peptide: 8558:TC OT 39 8521:Oxytocin 8483:Peptide: 8472:Oxytocin 8457:Oxytocin 8302:-derived 8248:-derived 8229:instead. 8184:Oleamide 8115:-derived 8096:instead. 7953:Dopamine 7764:Agmatine 7741:-derived 7580:Bombesin 7498:Kassinin 7248:hormones 7241:Hormones 7230:Peptides 6933:Hormones 6855:Chloride 6669:Skeleton 6659:Resistin 6558:Secretin 6540:Duodenum 6498:Thymulin 6399:Glucagon 6391:Pancreas 6372:Estrogen 6354:Placenta 6161:Cortisol 6054:Oxytocin 6016:Dopamine 5968:Hormones 5772:29468985 5737:25853137 5686:31960688 5678:19596026 5643:17981159 5527:12739464 5484:15280526 5449:18057218 5328:10880054 5238:38444963 5230:15555506 5191:17122081 5142:29923520 5134:17083331 5093:14647484 5027:15650630 4974:ProQuest 4962:15010588 4921:14175989 4894:43764321 4851:37668345 4732:18758414 4704:25130060 4540:21123762 4426:14991100 4369:22119947 4334:27450627 4310:: 5–17. 4236:21900458 4187:23123217 4138:10073614 4097:21686211 4056:23584881 3955:16210017 3947:15051143 3912:30252325 3885:26913138 3836:20346754 3787:36759747 3779:24259701 3682:35174328 3561:– 3540:– 3480:Copeptin 3465:Oxytocin 3453:See also 3378:oxytocin 3332:polyuria 3249:polyuria 3205:vomiting 3133:dopamine 3060:Octopus 3005:sea hare 2955:Inotocin 2893:Isotocin 2850:reptiles 2817:Oxytocin 2796:Oxytocin 2781:Cys-Tyr- 2749:Cys-Tyr- 2720:warthogs 2671:Cys-Tyr- 2642:oxytocin 2621:and the 2571:peptides 2563:oxytocin 2543:arginine 2417:platelet 2413:glycogen 2370:Actions 2255:Cortisol 2205:(TTFL), 2190:AVP gene 1995:tonicity 1989:Function 1931:nephrons 1911:vesicles 1884:AVP gene 1827:Wikidata 1520:Sources: 1300:dendrite 1076:amygdala 1068:monocyte 413:DrugBank 220:Agonists 129:ATC code 9131:Lithium 8987:LIT-001 8918:ABT-558 8913:ABT-436 8799:LIT-001 8553:LIT-001 8300:Vitamin 8194:RVD-Hpα 8149:AA-5-HT 7896:Taurine 7881:Proline 7871:Glycine 7814:Proline 7784:Glycine 7680:RVD-Hpα 7625:Ghrelin 7610:Galanin 7546:Orexins 6875:Protein 6865:Glucose 6563:Motilin 6530:Ghrelin 6525:Gastrin 6517:Stomach 6404:Insulin 6339:Relaxin 6334:Inhibin 6329:Activin 6301:Inhibin 6210:Thyroid 5780:3465601 5728:4371647 5595:5101576 5519:7556852 5440:2396735 5279:7545469 5182:2040022 5018:1356906 4970:3369276 4909:Surgery 4886:4084755 4843:3168310 4773:8390330 4668:2360697 4633:2830315 4502:1941619 4475:6916996 4467:9989497 4418:9988221 4325:5203950 4285:2295415 4277:9639350 4227:3233874 4178:3532715 4088:3116377 4047:3775849 3876:4756744 3827:2847497 3674:8277003 3665:9883978 3563:Ensembl 3542:Ensembl 3461:(SIADH) 3404:History 3297:heparin 3289:lithium 3261:alcohol 3177:kidneys 3131:(e.g., 3043:Octopus 2803:ratfish 2789:-Gly-NH 2757:-Gly-NH 2722:, some 2693:mammals 2679:-Gly-NH 2449:calcium 2391:calcium 2297:in the 2237:Ethanol 1929:of the 1897:in the 1895:neurons 1888:peptide 1880:hormone 1878:, is a 1653:UniProt 1608:Ensembl 1547:Species 1526:QuickGO 1280:cytosol 1001:pattern 727:Aliases 648:Density 570:Formula 422:DB00067 368:PubChem 293:kidneys 258:kidneys 163:tissues 161:Source 145:) 139: ( 137:H01BA01 9219:Orgasm 9149:Others 9062:YM-471 8844:YM-471 8839:YM-218 8824:SRX251 8819:SRX246 8568:WJ0679 8265:system 8139:2-ALPI 8060:Others 7891:Serine 7819:Serine 7459:Kinins 7392:Others 7006:Plasma 6850:Sodium 6687:Kidney 6649:Leptin 6608:/other 6468:Thymus 6409:Amylin 6283:Testis 6176:DHEA-S 5978:glands 5808:  5778:  5770:  5735:  5725:  5711:: 19. 5684:  5676:  5641:  5623:  5593:  5525:  5517:  5482:  5447:  5437:  5396:  5355:  5326:  5319:314363 5316:  5277:  5236:  5228:  5189:  5179:  5140:  5132:  5091:  5048:  5025:  5015:  4976:  4968:  4960:  4919:  4892:  4884:  4849:  4841:  4808:646620 4806:  4771:  4730:  4702:  4666:  4631:  4624:442524 4621:  4561:  4538:  4500:  4473:  4465:  4424:  4416:  4375:  4367:  4332:  4322:  4283:  4275:  4234:  4224:  4185:  4175:  4136:  4095:  4085:  4054:  4044:  4005:  3995:  3953:  3945:  3910:  3883:  3873:  3834:  3824:  3806:Neuron 3785:  3777:  3735:  3703:  3680:  3672:  3662:  3621:  3445:, and 3435:autism 3357:cancer 3342:Excess 3328:sodium 3201:nausea 3193:angina 3159:. The 2960:Locust 2932:Sharks 2916:skates 2716:hippos 2631:lysine 2551:lysine 2400:kidney 2382:AVPR1A 2278:, and 2138:serine 2110:sodium 2101:, and 2048:Kidney 1854:Human 1813:search 1811:PubMed 1686:P35455 1667:P01185 1563:Entrez 1172:BioGPS 751:192340 661:SMILES 513:ChEMBL 482:D00101 442:559126 382:644077 115: 8613:IX-01 8174:NAGly 8113:Lipid 7948:6-OHM 7840:GABOB 7568:Other 7449:Other 7188:Urine 7161:Other 6955:Renin 6799:urine 6720:Heart 6695:Renin 6625:IGF-2 6620:IGF-1 6606:Liver 6596:GLP-1 6578:Ileum 6460:Other 6344:GnSAF 6311:Ovary 5776:S2CID 5682:S2CID 5553:(PDF) 5523:S2CID 5257:Blood 5234:S2CID 5138:S2CID 4966:S2CID 4890:S2CID 4847:S2CID 4471:S2CID 4422:S2CID 4373:S2CID 4281:S2CID 3951:S2CID 3783:S2CID 3725:(PDF) 3678:S2CID 3209:fever 3173:liver 3155:or a 3009:leech 2880:Frogs 2846:birds 2821:Some 2815:Prol- 2798:(OXT) 2741:Some 2708:(LVP) 2691:Most 2517:AVP, 2511:from 2475:AVPR2 2458:brain 2404:brain 2396:Liver 2219:BMAL1 2215:Clock 2134:NKCC2 2032:) or 2015:voles 2004:urine 1950:brain 1886:as a 1874:) or 1866:), 1596:11998 1556:Mouse 1551:Human 1522:Amigo 1024:Mouse 1017:Human 964:Start 899:Mouse 863:Start 859:20p13 796:Human 759:88121 681:InChI 627:JSmol 493:ChEBI 317:Urine 289:liver 254:liver 8668:EDTA 8536:TGOT 8459:and 8227:here 8225:See 8169:NADA 8144:2-OG 8129:2-AG 8094:here 8092:See 7835:GABA 7809:NAAG 7794:GSSG 7789:GSNO 7246:see 7120:Kt/V 6860:Urea 6788:and 6171:DHEA 6107:ACTH 6102:CLIP 6097:POMC 6026:GHRH 6006:GnRH 5924:2bn2 5909:1npo 5894:1jk6 5879:1jk4 5806:ISBN 5768:PMID 5733:PMID 5674:PMID 5639:PMID 5591:PMID 5515:PMID 5480:PMID 5445:PMID 5394:ISBN 5353:ISBN 5324:PMID 5275:PMID 5226:PMID 5187:PMID 5130:PMID 5089:PMID 5046:ISBN 5023:PMID 4958:PMID 4917:PMID 4882:PMID 4839:PMID 4804:PMID 4769:PMID 4728:PMID 4700:PMID 4664:PMID 4629:PMID 4559:ISBN 4536:PMID 4498:PMID 4463:PMID 4445:Cell 4414:PMID 4396:Cell 4365:PMID 4330:PMID 4273:PMID 4232:PMID 4183:PMID 4134:PMID 4093:PMID 4052:PMID 4003:OCLC 3993:ISBN 3943:PMID 3908:PMID 3881:PMID 3832:PMID 3775:PMID 3733:ISBN 3701:ISBN 3670:PMID 3619:ISBN 3392:and 3368:and 3281:and 3227:and 2712:Pigs 2635:pigs 2484:cAMP 2423:and 2359:Type 2217:and 2211:CK1E 2207:Per2 2199:gene 2140:and 2124:and 2083:urea 2076:cAMP 2038:pigs 1960:and 1903:axon 1146:hair 1007:Bgee 955:Band 916:Chr. 854:Band 813:Chr. 747:OMIM 473:KEGG 453:UNII 402:2168 291:and 267:data 256:and 213:OXTR 156:data 8548:CA7 8282:ATP 8277:AMP 8272:ADP 8199:SEA 8189:PEA 8179:OEA 8164:LPI 8159:DEA 7914:GHB 7845:GHB 7804:NAA 7685:VGF 7281:1–8 6738:BNP 6733:ANP 6700:EPO 6568:VIP 6553:GIP 6548:CCK 6367:HPL 6362:hCG 6296:AMH 6264:PTH 6112:MSH 6087:TSH 6077:FSH 6036:MCH 6021:CRH 6011:TRH 5760:doi 5723:PMC 5713:doi 5666:doi 5631:doi 5617:120 5583:doi 5507:doi 5472:doi 5435:PMC 5427:doi 5386:doi 5314:PMC 5306:doi 5302:106 5265:doi 5218:doi 5177:PMC 5169:doi 5165:148 5120:doi 5079:doi 5013:PMC 5005:doi 5001:241 4948:doi 4874:doi 4831:doi 4796:doi 4792:113 4759:doi 4692:doi 4656:doi 4652:258 4619:PMC 4611:doi 4528:doi 4524:300 4494:259 4453:doi 4404:doi 4357:doi 4320:PMC 4312:doi 4308:202 4263:doi 4222:PMC 4214:doi 4210:301 4173:PMC 4165:doi 4161:182 4124:doi 4083:PMC 4079:122 4042:PMC 4034:doi 3974:MSD 3935:doi 3931:125 3871:PMC 3863:doi 3822:PMC 3814:doi 3767:doi 3660:PMC 3652:doi 3648:337 3299:or 3241:BUN 3135:or 2787:Leu 2783:Ile 2755:Arg 2751:Ile 2677:Arg 2673:Phe 2613:-NH 2611:Gly 2607:Arg 2603:Pro 2599:Cys 2595:Asn 2591:Gln 2587:Phe 2583:Tyr 2579:Cys 2227:AVP 2223:AVP 2197:AVP 2030:LVP 1893:in 1872:AVP 1864:ADH 1577:551 977:End 876:End 779:OMA 775:AVP 767:417 755:MGI 734:AVP 706:AVP 618:.24 616:084 538:EPA 372:CID 142:WHO 9185:: 9167:II 9165:, 8861:1B 8717:1A 8588:; 8543:; 8402:O) 8354:S) 7232:: 6988:: 6129:GH 6082:LH 5774:. 5766:. 5756:18 5754:. 5731:. 5721:. 5707:. 5703:. 5680:. 5672:. 5662:30 5660:. 5637:. 5629:. 5615:. 5603:^ 5589:. 5579:98 5577:. 5535:^ 5521:. 5513:. 5503:16 5501:. 5478:. 5468:19 5466:. 5443:. 5433:. 5423:19 5421:. 5417:. 5392:. 5322:. 5312:. 5300:. 5296:. 5273:. 5261:86 5259:. 5255:. 5232:. 5224:. 5214:46 5212:. 5208:. 5185:. 5175:. 5163:. 5159:. 5136:. 5128:. 5114:. 5110:. 5087:. 5075:29 5073:. 5069:. 5021:. 5011:. 4999:. 4995:. 4972:. 4964:. 4956:. 4944:21 4942:. 4938:. 4913:56 4911:. 4888:. 4880:. 4870:72 4868:. 4845:. 4837:. 4827:28 4825:. 4802:. 4790:. 4767:. 4755:40 4753:. 4749:. 4724:14 4722:. 4698:. 4688:43 4686:. 4662:. 4650:. 4627:. 4617:. 4607:81 4605:. 4601:. 4582:. 4534:. 4522:. 4510:^ 4492:. 4469:. 4461:. 4449:96 4447:. 4443:. 4420:. 4412:. 4400:96 4398:. 4394:. 4371:. 4363:. 4353:14 4351:. 4328:. 4318:. 4306:. 4302:. 4279:. 4271:. 4259:83 4257:. 4253:. 4230:. 4220:. 4208:. 4204:. 4181:. 4171:. 4159:. 4155:. 4132:. 4120:10 4118:. 4114:. 4091:. 4077:. 4073:. 4050:. 4040:. 4030:17 4028:. 4024:. 4001:. 3972:. 3949:. 3941:. 3929:. 3902:. 3879:. 3869:. 3859:24 3857:. 3830:. 3820:. 3810:65 3808:. 3804:. 3781:. 3773:. 3763:47 3761:. 3747:^ 3676:. 3668:. 3658:. 3646:. 3642:. 3596:. 3578:. 3549:^ 3528:^ 3449:. 3441:, 3437:, 3412:. 3400:. 3376:, 3295:, 3291:, 3277:, 3273:, 3269:, 3231:. 3211:, 3203:, 3199:, 3191:, 3151:, 3007:, 3003:, 2999:, 2860:, 2856:, 2852:, 2848:, 2825:, 2718:, 2714:, 2456:, 2411:, 2398:, 2286:. 2274:, 2097:, 2044:. 2010:. 1956:, 1945:. 1524:/ 983:bp 970:bp 882:bp 869:bp 777:; 773:: 769:; 765:: 761:; 757:: 753:; 749:: 596:12 590:15 584:65 578:46 277:1% 227:, 211:, 204:, 201:1B 197:, 194:1A 170:; 87:oʊ 81:eɪ 9169:) 9163:I 9161:( 9137:) 9133:( 8965:2 8963:V 8859:V 8715:V 8674:L 8449:e 8442:t 8435:v 8411:) 8409:2 8400:2 8388:) 8386:3 8352:2 8049:p 8041:m 8013:p 8005:m 7723:e 7716:t 7709:v 7559:B 7554:A 7536:U 7531:S 7526:N 7521:B 7222:e 7215:t 7208:v 7153:) 7144:( 7050:) 7046:( 7013:) 6999:( 6778:e 6771:t 6764:v 6233:4 6231:T 6225:3 6223:T 5960:e 5953:t 5946:v 5854:e 5847:t 5840:v 5825:. 5782:. 5762:: 5739:. 5715:: 5709:2 5688:. 5668:: 5645:. 5633:: 5597:. 5585:: 5562:. 5529:. 5509:: 5486:. 5474:: 5451:. 5429:: 5402:. 5388:: 5361:. 5330:. 5308:: 5281:. 5267:: 5240:. 5220:: 5193:. 5171:: 5144:. 5122:: 5116:6 5095:. 5081:: 5054:. 5029:. 5007:: 4980:. 4950:: 4923:. 4896:. 4876:: 4853:. 4833:: 4810:. 4798:: 4775:. 4761:: 4734:. 4706:. 4694:: 4670:. 4658:: 4635:. 4613:: 4584:1 4567:. 4542:. 4530:: 4504:. 4477:. 4455:: 4428:. 4406:: 4379:. 4359:: 4336:. 4314:: 4287:. 4265:: 4238:. 4216:: 4189:. 4167:: 4140:. 4126:: 4099:. 4058:. 4036:: 4009:. 3957:. 3937:: 3914:. 3887:. 3865:: 3838:. 3816:: 3789:. 3769:: 3741:. 3709:. 3684:. 3654:: 3627:. 3600:. 3582:. 3364:( 3051:2 3033:2 3017:2 2986:2 2968:2 2950:2 2924:2 2906:2 2888:2 2870:2 2835:2 2811:2 2791:2 2766:† 2759:2 2732:2 2701:2 2681:2 2623:C 2615:2 2609:- 2605:- 2601:- 2597:- 2593:- 2589:- 2585:- 2581:- 2482:/ 2447:/ 2389:/ 2168:. 2128:. 2105:. 2028:( 1917:( 1870:( 1862:( 901:) 798:) 781:: 629:) 614:1 602:2 599:S 593:O 587:N 581:H 575:C 540:) 536:( 208:2 206:V 199:V 192:V 111:/ 108:n 105:ɪ 102:s 99:ɛ 96:r 93:p 90:ˈ 84:z 78:v 75:ˌ 72:/ 25:.

Index

Vasopressin (medication)
vasopressors


/ˌvzˈprɛsɪn/
ATC code
H01BA01
WHO
Physiological
tissues
Supraoptic nucleus
paraventricular nucleus of hypothalamus
Receptors
V1A
V1B
V2
OXTR
Agonists
Felypressin
desmopressin
Antagonists
Diuretics
Metabolism
liver
kidneys
Pharmacokinetic
Protein binding
Metabolism
liver
kidneys

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.