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repair of a site specific, programmed double-strand break, a highly organized process. This process replaces one mating type allelic DNA sequence with the sequence encoding the alternative mating-type allele. When two haploid cells of opposite mating type come into contact they can mate to form a
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Noma K, Sugiyama T, Cam H, Verdel A, Zofall M, Jia S, Moazed D, Grewal S (2004). "RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing". Nat Genet 36 (11): 1174-80.
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cells in a colony from one mating-type to the other. Mating-type switching can occur as frequently as once every generation. Switching involves
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responsible for genomic maintenance in many organisms. Mating type regions have also been well studied in
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has the capability of undergoing mating-type switching, that is conversion of some
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Staben C, Yanofsky C. (1990). Neurospora crassa a mating-type region.
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212:"Mating-type genes and MAT switching in Saccharomyces cerevisiae"
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of the organism and therefore determine key events in its
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