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Osteofibrous dysplasia

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49: 130: 94:– a tumor involving subcutaneous long bones – stating the common cause to be fibrovascular defect. However, the latter is distinguished from an osteofibrous dysplasia by the presence of soft tissue extension, intramedullary extension, periosteal reaction and presence of hyperchromic epithelial cells under the microscope. 171:
Osteofibrous dysplasia is treated with marginal resection with or without bone grafting, depending on the size of the lesion and the extent of bony involvement. However, due to the high rate of recurrence in skeletally immature individuals, this procedure is usually postponed until skeletal maturity.
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The tibia is the most commonly involved bone, accounting for 85% of cases. It is usually painless, although there may be localized pain or fracture, and presents as a localized firm swelling of the tibia in children less than two decades old (median age for males 10, females 13). Several authors
264:"A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the literature" 246: 161: 65:
condition with no known cause. It is considered a fibrovascular defect. Campanacci described this condition in two leg bones, the
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Campanacci M (August 1976). "Osteofibrous dysplasia of long bones a new clinical entity".
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Hatori M, Watanabe M, Hosaka M, Sasano H, Narita M, Kokubun S (2006).
70: 73:, and coined the term. This condition should be differentiated from 66: 124: 101:, although osteofibrous dysplasia is more likely to show an 238:
MRI of bone and soft tissue tumors and tumorlike lesions
141: 311: 344: 315: 36: 26: 21: 97:Osteofibrous dysplasia may also be mistaken for 8: 90:have related this non-neoplastic lesion to 312: 47: 18: 279: 230: 228: 181: 216:Robert Mervyn Letts (17 August 2021), 7: 14: 162:Juvenile active ossifying fibroma 128: 1: 402: 159: 235:Steven P. Meyers (2008). 99:fibrous dysplasia of bone 79:fibrous dysplasia of bone 191:Ital J Orthop Traumatol 219:Osteofibrous Dysplasia 59:Osteofibrous dysplasia 22:Osteofibrous dysplasia 75:nonossifying fibroma 307:E-medicine overview 281:10.1620/tjem.209.53 103:immunohistochemical 386:Skeletal disorders 345:External resources 140:. You can help by 61:is a rare, benign 368: 367: 158: 157: 56: 55: 31:Ossifying fibroma 16:Medical condition 393: 313: 294: 293: 283: 268:Tohoku J Exp Med 259: 253: 252: 232: 223: 222: 213: 207: 206: 186: 153: 150: 132: 125: 52: 51: 19: 401: 400: 396: 395: 394: 392: 391: 390: 371: 370: 369: 364: 363: 359:article/1256595 340: 339: 324: 303: 298: 297: 261: 260: 256: 249: 234: 233: 226: 215: 214: 210: 188: 187: 183: 178: 169: 164: 154: 148: 145: 138:needs expansion 123: 111:neurofibromin 1 87: 46: 17: 12: 11: 5: 399: 397: 389: 388: 383: 373: 372: 366: 365: 362: 361: 349: 348: 346: 342: 341: 338: 337: 325: 320: 319: 317: 316:Classification 310: 309: 302: 301:External links 299: 296: 295: 254: 247: 224: 208: 180: 179: 177: 174: 168: 165: 156: 155: 135: 133: 122: 119: 86: 83: 63:non-neoplastic 54: 53: 40: 34: 33: 28: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 398: 387: 384: 382: 379: 378: 376: 360: 356: 355: 351: 350: 347: 343: 336: 332: 331: 327: 326: 323: 318: 314: 308: 305: 304: 300: 291: 287: 282: 277: 273: 269: 265: 258: 255: 250: 248:9783131354211 244: 240: 239: 231: 229: 225: 221: 220: 212: 209: 204: 200: 197:(2): 221–37. 196: 192: 185: 182: 175: 173: 166: 163: 152: 143: 139: 136:This section 134: 131: 127: 126: 120: 118: 116: 115:S-100 protein 112: 108: 104: 100: 95: 93: 84: 82: 80: 76: 72: 68: 64: 60: 50: 44: 41: 39: 35: 32: 29: 25: 20: 381:Osteopathies 352: 328: 274:(1): 53–59. 271: 267: 257: 237: 218: 211: 194: 190: 184: 170: 146: 142:adding to it 137: 105:reaction to 96: 92:adamantinoma 88: 85:Presentation 58: 57: 30: 107:osteonectin 27:Other names 375:Categories 241:. Thieme. 176:References 160:See also: 149:March 2023 354:eMedicine 167:Treatment 121:Diagnosis 38:Specialty 290:16636523 43:Oncology 335:D018214 203:1024109 288:  245:  201:  113:, and 71:fibula 45:  67:tibia 330:MeSH 286:PMID 243:ISBN 199:PMID 77:and 69:and 276:doi 272:209 144:. 377:: 357:: 333:: 284:. 270:. 266:. 227:^ 193:. 117:. 109:, 81:. 322:D 292:. 278:: 251:. 205:. 195:2 151:) 147:(

Index

Specialty
Oncology
Edit this on Wikidata
non-neoplastic
tibia
fibula
nonossifying fibroma
fibrous dysplasia of bone
adamantinoma
fibrous dysplasia of bone
immunohistochemical
osteonectin
neurofibromin 1
S-100 protein

adding to it
Juvenile active ossifying fibroma
PMID
1024109
Osteofibrous Dysplasia


MRI of bone and soft tissue tumors and tumorlike lesions
ISBN
9783131354211
"A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the literature"
doi
10.1620/tjem.209.53
PMID
16636523

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