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94:– a tumor involving subcutaneous long bones – stating the common cause to be fibrovascular defect. However, the latter is distinguished from an osteofibrous dysplasia by the presence of soft tissue extension, intramedullary extension, periosteal reaction and presence of hyperchromic epithelial cells under the microscope.
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Osteofibrous dysplasia is treated with marginal resection with or without bone grafting, depending on the size of the lesion and the extent of bony involvement. However, due to the high rate of recurrence in skeletally immature individuals, this procedure is usually postponed until skeletal maturity.
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The tibia is the most commonly involved bone, accounting for 85% of cases. It is usually painless, although there may be localized pain or fracture, and presents as a localized firm swelling of the tibia in children less than two decades old (median age for males 10, females 13). Several authors
264:"A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the literature"
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condition with no known cause. It is considered a fibrovascular defect. Campanacci described this condition in two leg bones, the
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Campanacci M (August 1976). "Osteofibrous dysplasia of long bones a new clinical entity".
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Hatori M, Watanabe M, Hosaka M, Sasano H, Narita M, Kokubun S (2006).
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MRI of bone and soft tissue tumors and tumorlike lesions
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99:fibrous dysplasia of bone
79:fibrous dysplasia of bone
191:Ital J Orthop Traumatol
219:Osteofibrous Dysplasia
59:Osteofibrous dysplasia
22:Osteofibrous dysplasia
75:nonossifying fibroma
307:E-medicine overview
281:10.1620/tjem.209.53
103:immunohistochemical
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345:External resources
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27:Other names
375:Categories
241:. Thieme.
176:References
160:See also:
149:March 2023
354:eMedicine
167:Treatment
121:Diagnosis
38:Specialty
290:16636523
43:Oncology
335:D018214
203:1024109
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330:MeSH
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