74:
148:
39:
174:. Metastases are rare at presentation but may occur in up to 30% of patients during the disease course. Prognosis is excellent, with overall survival of 85% at 10 years, but is lower when wide surgical margins cannot be obtained. This tumor is insensitive to radiation so
618:
630:
734:
456:
Gleason, Briana C.; Liegl-Atzwanger, Bernadette (2008). "Osteofibrous
Dysplasia and Adamantinoma in Children and Adolescents: A Clinicopathologic Reappraisal".
113:
Patients typically present with swelling with or without pain. The slow-growing tumor predominantly arises in long bones in a subcortical location (95% in the
1037:
194:
was first recognized in 1827 by Cusack. Still, it did not yet have any designation. In 1885, this kind of odontogenic neoplasm was designated as an
727:
548:
R.H. Ivey; H.R. Churchill (1930). "The need of a standardized surgical and pathological classification of tumors and anomalies of dental origin".
513:
360:"A classic adamantinoma arising from osteofibrous dysplasia-like adamantinoma in the lower leg: a case report and review of the literature"
638:
720:
285:
403:
781:
433:
Springfield DS, Rosenberg AE, Mankin HJ, Mindell ER (1994). "Relationship between osteofibrous dysplasia and adamantinoma".
98:, making up less than 1% of all bone cancers. It almost always occurs in the bones of the lower leg and involves both
882:
159:
158:
of the affected area show a well defined tumour in bone, with multiple lobules giving a "soap bubble" appearance.
978:
649:
870:
508:. Vol. 3 (5th ed.). Lyon (France): International Agency for Research on Cancer. pp. 463–466.
924:
786:
700:
132:
125:
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906:
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147:
423:
Fischer B. Uber ein primares
Adamantinom der Tibia. 12. Frankfurt: Zeitschr. f. Path.; 1913:422-441.
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58:
38:
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371:
327:
317:
241:
233:
960:
820:
748:
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WHO Classification of
Tumours Editorial Board, ed. (2020). "Adamantinoma of long bones".
399:
970:
894:
877:
332:
305:
246:
221:
87:
1026:
825:
791:
200:
191:
20:
485:
151:
Radiograph showing an adamantinoma in the distal tibia with lytic expansive changes.
952:
929:
844:
834:
689:
567:
Madhup, R; Kirti, S; Bhatt, M; Srivastava, M; Sudhir, S; Srivastava, A (Jan 2006).
175:
67:
50:
654:
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860:
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99:
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237:
442:
358:
Hatori M, Watanabe M, Hosaka M, Sasano H, Narita M, Kokubun S (May 2006).
322:
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may be a precursor of adamantinoma or a regressive phase of adamantinoma.
1007:
695:
63:
610:
376:
359:
830:
529:
L. Malassez (1885). "Sur Le role des debris epitheliaux papdentaires".
622:
118:
131:
Histologically, islands of epithelial cells are found in a fibrous
155:
146:
114:
569:"Giant ameloblastoma of jaw successfully treated by radiotherapy"
643:
716:
505:
Soft Tissue and Bone
Tumours: WHO Classification of Tumours
139:
and eccentric, with cystic zones resembling soap bubbles.
53:) of an adamantinoma showing the biphasic histomorphology.
304:
Jain D, Jain VK, Vasishta RK, Ranjan P, Kumar Y (2008).
306:"Adamantinoma: A clinicopathological review and update"
198:
by
Malassez. It was finally renamed to the modern name
105:
The condition was first described by
Fischer in 1913.
600:
998:
991:
969:
951:
942:
915:
843:
811:
802:
755:
675:
604:
57:
31:
220:Brazis PW, Miller NR, Lee AG, Holliday MJ (1995).
162:can provide a more useful guide to its severity.
190:The typically benign odontogenic tumor known as
222:"Neuro-ophthalmologic Aspects of Ameloblastoma"
353:
351:
299:
297:
728:
277:Orthopaedic Oncology: Diagnosis and Treatment
8:
178:is not typically used unless the cancer has
269:
267:
265:
995:
948:
808:
735:
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713:
601:
135:. The tumor is typically well-demarcated,
72:
37:
28:
584:
497:
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331:
321:
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170:Treatment consists of wide resection or
19:For the cancer of developing teeth, see
212:
458:American Journal of Surgical Pathology
406:from the original on 25 December 2008
7:
400:"Adamantinoma: Overview - eMedicine"
1038:Osseous and chondromatous neoplasia
14:
16:Rare bone tumor in the lower leg
782:Primitive neuroectodermal tumor
204:in 1930 by Ivey and Churchill.
182:to the lungs or other organs.
1:
94: 'very hard') is a rare
470:10.1097/PAS.0b013e318150d53e
280:. Thieme. pp. 143–145.
1054:
883:Mesenchymal chondrosarcoma
18:
586:10.1016/j.ooe.2005.08.004
274:Ernest U. Conrad (2008).
102:and osteofibrous tissue.
45:
36:
979:Giant-cell tumor of bone
531:Arch Physiol Norm Pathol
871:Extraskeletal chondroma
550:Am Assoc Dent Sch Trans
238:10.1055/s-2008-1058921
152:
126:osteofibrous dysplasia
907:Chondromyxoid fibroma
888:Myxoid chondrosarcoma
435:Clin Orthop Relat Res
323:10.1186/1746-1596-3-8
150:
537:: 309–340 6:379–449.
900:Osteochondromatosis
573:Oral Oncology Extra
377:10.1620/tjem.209.53
676:External resources
364:Tohoku J. Exp. Med
153:
1020:
1019:
1016:
1015:
987:
986:
938:
937:
925:Ossifying fibroma
710:
709:
515:978-92-832-4503-2
81:
80:
26:Medical condition
1045:
996:
949:
866:Enchondromatosis
809:
765:Multiple myeloma
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1023:
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961:Chondroblastoma
934:
911:
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821:Osteoid osteoma
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437:(309): 234–44.
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226:Skull Base Surg
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24:
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895:Osteochondroma
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891:
890:
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878:Chondrosarcoma
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605:Classification
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464:(3): 363–376.
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826:Osteoblastoma
824:
822:
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792:Ewing sarcoma
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232:(4): 233–44.
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201:ameloblastoma
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192:ameloblastoma
185:
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56:
52:
51:H&E stain
48:
44:
40:
35:
30:
22:
21:ameloblastoma
1033:Rare cancers
953:Chondroblast
930:Fibrosarcoma
845:Chondroblast
835:osteosarcoma
787:Ewing family
775:Adamantinoma
774:
694:
683:
659:
648:
637:
629:
617:
579:(1): 22–25.
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408:. Retrieved
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367:
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313:
310:Diagn Pathol
309:
276:
229:
225:
215:
199:
196:adamantinoma
195:
189:
180:metastasized
176:chemotherapy
169:
154:
130:
123:
112:
109:Presentation
104:
91:
84:Adamantinoma
83:
82:
68:rheumatology
32:Adamantinoma
861:enchondroma
857:ecchondroma
743:Tumours of
370:(1): 53–9.
96:bone cancer
92:adamantinos
1027:Categories
813:Osteoblast
804:Metaphysis
661:DiseasesDB
556:: 240–245.
410:2009-01-04
208:References
172:amputation
137:osteolytic
100:epithelial
86:(from
47:Micrograph
1000:Notochord
944:Epiphysis
853:Chondroma
770:Epithelia
757:Diaphysis
749:cartilage
685:eMedicine
166:Treatment
143:Diagnosis
59:Specialty
1008:Chordoma
696:Orphanet
690:radio/11
634:: 9310/0
486:22076947
478:18300815
404:Archived
386:16636523
342:18279517
256:17170964
64:Oncology
971:Myeloid
917:Fibrous
831:Osteoma
655:D050398
626:: C40.2
443:7994967
333:2276480
247:1656531
186:History
124:Benign
49:(using
644:102660
512:
484:
476:
441:
384:
340:
330:
284:
254:
244:
156:X-rays
133:stroma
119:fibula
70:
992:Other
701:55881
666:31676
631:ICD-O
482:S2CID
316:: 8.
115:tibia
90:
88:Greek
747:and
745:bone
650:MeSH
639:OMIM
510:ISBN
474:PMID
439:PMID
382:PMID
338:PMID
282:ISBN
252:PMID
619:ICD
581:doi
466:doi
372:doi
368:209
328:PMC
318:doi
242:PMC
234:doi
160:MRI
121:).
117:or
1029::
699::
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664::
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623:10
577:42
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494:^
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296:^
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833:/
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611:D
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388:.
374::
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320::
314:3
290:.
258:.
236::
230:5
23:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
