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in 1965 by Alvin Tarlov and Eugene
Kennedy using carbon tracers reveals increased levels of glycerol and serine, in addition to those of phosphorus, in the presence of increasing levels of beta-galactoside accumulation. The existence of these otherwise inert amino acids in relation to increasing levels of galactosides indicates a far less direct correlation between increasing levels of permease activity with increasing amounts of inorganic phosphate in the cell.
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in phospholipids was found to be increased under conditions of maximal activity in beta-galactoside permease. Insofar, Nikaido concluded that this correlation suggested that phospholipids are involved in the process of transporting beta-galactosides through the cell membrane. However, later research
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Beta-galactoside permeases can describe any transport proteins that enable a cell to uptake, and thus accumulate, beta-galactosides. One known example of these transport proteins is the
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for the purpose of binding galactoside molecules that have been solubilized. The protein is part of a system whose main function is to catalyze the accumulation and transport of
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75:. This strain of beta-galactoside permease is known it transport melibiose and other galactosides across the cell membrane using
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Cammack, Richard; Atwood, Teresa; Campbell, Peter; Parish, Howard; Smith, Anthony; Vella, Frank; Stirling, John (2006-06-29).
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in 1962 suggest a direct relationship between the amount of beta-galactoside permease activity in a cell and the
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336:"The Galactoside Permease System and the Metabolism of Phospholipids in Escherichia coli"
154:"Temperature-Sensitive Mutants of Escherichia Coli Affecting Beta-Galactoside Transport"
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Function of beta-galactoside permease in the membrane of a cell
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bacterial cells under varying conditions, the level of
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Tarlov, Alvin R.; Kennedy, Eugene P. (January 1965).
306:. New York, NY: Academic Press Inc. pp. 218–9.
300:Paoletti, Rodolfo; Kritchevsky, David (1966).
57:across the permeable barrier of a membrane.
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95:Involvement of the phosphatidic acid cycle
45:, and is found bound to the membrane of a
382:at the U.S. National Library of Medicine
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152:Crandall, M; Koch, A.L. (February 1971).
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61:MelB carrier protein and its properties
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203:"Lecture 16 - Prokaryotic Regulation"
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303:Advances in Lipid Research, Volume 4
343:The Journal of Biological Chemistry
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356:10.1016/S0021-9258(18)97613-1
170:10.1128/jb.105.2.609-619.1971
275:"Melibiose Carrier Protein"
226:. Oxford University Press.
201:Szauter, Paul (Fall 2013).
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380:Permease,+beta-galactoside
111:. In his experiments with
384:Medical Subject Headings
158:Journal of Bacteriology
223:B-galactoside permease
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281:. UniProt Consortium
107:of phospholipids in
28:Galactoside permease
207:Biology202 Genetics
400:Transport proteins
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99:Early studies by
55:beta-galactosides
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134:Lactose permease
16:Membrane protein
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38:gene of the
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89:cotransport
140:References
53:and other
362:March 11,
259:ignored (
249:cite book
67:melibiose
394:Category
128:See also
87:ions in
77:hydrogen
279:UniProt
188:5541536
109:E. coli
85:lithium
72:E. coli
51:lactose
32:protein
386:(MeSH)
319:21 May
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285:21 May
239:21 May
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179:248434
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81:sodium
43:operon
339:(PDF)
83:, or
30:is a
364:2017
321:2017
308:ISBN
287:2017
261:help
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228:ISBN
184:PMID
115:and
47:cell
36:lacY
351:doi
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174:PMC
166:doi
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