Knowledge (XXG)

Overactive bladder

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574:, can help strengthen the muscles that control urination. Fluid management, which focuses on avoiding excessive caffeine and alcohol intake, is advised to reduce the rate at which the bladder fills and minimize irritation to the bladder. Weight management and maintaining a healthy diet contribute to overall bladder health, especially when weight loss is able to reduce abdominal compression of the bladder. Adopting these behavioral and lifestyle changes can often improve the condition and enhance the effectiveness of other treatment approaches. 2867: 497:
specific to overactive bladder. General questionnaires include: American Urological Association Symptom Index (AUASI), Urogenital Distress Inventory (UDI), Incontinence Impact Questionnaire (IIQ), and Bristol Female Lower Urinary Tract Symptoms (BFLUTS). Overactive bladder questionnaires include: Overactive Bladder Questionnaire (OAB-q), Urgency Questionnaire (UQ), Primary OAB Symptom Questionnaire (POSQ), and the International Consultation on Incontinence Questionnaire (ICIQ).
516:(blood in the urine) which are typically absent in OAB. Bladder cancer usually includes hematuria and can include pain, both not associated with OAB, and the common symptoms of OAB (urgency, frequency, and nocturia) may be absent. BPH frequently includes symptoms at the time of voiding as well as sometimes including pain or hematuria, and all of these are not usually present in OAB. 112: 36: 950:. Botulinum Toxin A injections into the bladder wall can suppress involuntary bladder contractions by blocking nerve signals and may be effective for up to 9 months. The growing knowledge of pathophysiology of overactive bladder fueled a huge amount of basic and clinical research in this field of pharmacotherapy. 528:
There is some controversy about the classification and diagnosis of OAB. Some sources classify overactive bladder into two different variants: "wet" (i.e., an urgent need to urinate with involuntary leakage) or "dry" (i.e., an urgent need to urinate but no involuntary leakage). Wet variants are more
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is considered abnormal if the person urinates more than eight times in a day. This frequency is usually monitored by having the person keep a voiding diary where they record urination episodes. The number of episodes varies depending on sleep, fluid intake, medications, and up to seven is considered
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is increasing. However, a recent Finnish population-based survey suggested that the number of people affected had been largely overestimated due to methodological shortcomings regarding age distribution and low participation (in earlier reports). It is suspected, then, that OAB affects approximately
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Patients taking oxybutynin and other anticholinergic drugs experience a 70% reduction of incontinence episode frequency, on average. Approximately 1 in 4 patients experience complete dryness while taking oxybutynin. Therefore, medication management alone is sufficient for a substantial minority, but
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It is important that the clinician and the person with overactive bladder both reach a consensus on the term, 'urgency.' Some common phrases used to describe OAB include, 'When I've got to go, I've got to go,' or 'When I have to go, I have to rush, because I think I will wet myself.' Hence the term,
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is a symptom where the person complains of interrupted sleep because of an urge to void and, like the urinary frequency component, is affected by similar lifestyle and medical factors. Individual waking events are not considered abnormal, one study in Finland established two or more voids per night
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Overactive bladder affects approximately 11% of the population and more than 40% of people with overactive bladder have incontinence. Conversely, about 40% to 70% of urinary incontinence is due to overactive bladder. Overactive bladder is not life-threatening, but most people with the condition have
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Psychometrically robust self-completion questionnaires are generally recognized as a valid way of measuring a person's signs and symptoms, but there does not exist a single ideal questionnaire. These surveys can be divided into two groups: general surveys of lower urinary tract symptoms and surveys
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Because overactive bladder is most commonly associated with aging, the majority of patients experience symptoms (with or without incontinence) for the rest of their lives. A minority of age-related OAB cases may be cured or indefinitely suppressed by medications and behavioral modification. If the
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Most patients are not able to eliminate incontinence and other symptoms of OAB with lifestyle and behavioral modifications alone. However, numerous studies have demonstrated that these therapies are effective in improving quality of life, and some data shows that they increase the likelihood that
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Urge incontinence is a form of urinary incontinence characterized by the involuntary loss of urine occurring for no apparent reason while feeling urinary urgency as discussed above. Like frequency, the person can track incontinence in a diary to assist with diagnosis and management of symptoms.
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Overactive bladder is estimated to occur in 7–27% of men and 9–43% of women. It becomes more common with age. Some studies suggest that the condition is more common in women, especially when associated with loss of bladder control. Economic costs of overactive bladder were estimated in the United
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type, are only recommended if other measures are not effective. They are no more effective than behavioral methods; however, they are associated with side effects, particularly in older people. Some non-invasive electrical stimulation methods appear effective while they are in use. Injections of
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The usual first suggested treatment for a person with overactive bladder is a combination of lifestyle changes, exercises to strengthen the person's pelvic floor, and manage how much the person drinks and when during the day ("fluid management"). Patients who continue to experience incontinence
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is considered the hallmark symptom of OAB, but there are no clear criteria for what constitutes urgency and studies often use other criteria. Urgency is currently defined by the International Continence Society (ICS), as of 2002, as "Sudden, compelling desire to pass urine that is difficult to
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The American Urological Association reports studies showing rates as low as 7% to as high as 27% in men and rates as low as 9% to 43% in women. Urge incontinence was reported as higher in women. Older people are more likely to be affected, and the number of symptoms increases with age.
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Behavioral and lifestyle changes are commonly recommended as the first-line option for treating overactive bladder. These include bladder training, which involves scheduled voiding (urination) and gradually increasing the time between bathroom visits. Pelvic floor exercises, known as
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Shumaker SA, Wyman JF, Uebersax JS, McClish D, Fantl JA (October 1994). "Health-related quality of life measures for women with urinary incontinence: the Incontinence Impact Questionnaire and the Urogenital Distress Inventory. Continence Program in Women (CPW) Research Group".
301:) may occur with this condition. This condition is also sometimes characterized by a sudden and involuntary contraction of the bladder muscles, in response to excitement or anticipation. This in turn leads to a frequent and urgent need to urinate. 324:
may worsen the symptoms. People often have the symptoms for a long time before seeking treatment and the condition is sometimes identified by caregivers. Diagnosis is based on a person's signs and symptoms and requires other problems such as
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Gormley EA, Lightner DJ, Burgio KL, Chai TC, Clemens JQ, Culkin DJ, Das AK, Foster HE, Scarpero HM, Tessier CD, Vasavada SP (December 2012). "Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guideline".
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Scarneciu, Ioan; Lupu, Sorin; Bratu, Ovidiu Gabriel; Teodorescu, Andreea; Maxim, Laurian Stefan; Brinza, Adrian; Laculiceanu, Alexandru Georgian; Rotaru, Ruxandra Maria; Lupu, Aura-Mihaela; Scarneciu, Camelia Cornelia (2021-10-14).
980:, which is part of the small intestine. This procedure is rarely performed, and is only done for patients who have proven resistant to all other forms of treatment. This procedure can greatly enlarge urine volume in the bladder. 445:. It is also possible that the increased contractile nature originates from within the urothelium and lamina propria, and abnormal contractions in this tissue could stimulate dysfunction in the detrusor or whole bladder. 1282:
Hargreaves, Emma; Baker, Katherine; Barry, Gill; Harding, Christopher; Zhang, Yingying; Kandala, Ngianga-Bakwin; Zhang, Xiaowen; Kernohan, Ashleigh; Clarkson, Carl E (2022-09-23). Cochrane Incontinence Group (ed.).
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defer." The previous definition was "Strong desire to void accompanied by fear of leakage or pain." The definition does not address the immediacy of the urge to void and has been criticized as subjective.
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Tikkinen KA, Johnson TM, Tammela TL, Sintonen H, Haukka J, Huhtala H, Auvinen A (March 2010). "Nocturia frequency, bother, and quality of life: how often is too often? A population-based study in Finland".
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common than dry variants. The distinction is not absolute; one study suggested that many classified as "dry" were actually "wet" and that people with no history of any leakage may have had other syndromes.
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Milsom I, Abrams P, Cardozo L, Roberts RG, ThΓΌroff J, Wein AJ (June 2001). "How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study".
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is in place, the catheter may be blocked by blood, thick sediment, or a kink in the catheter or drainage tubing. Sometimes spasms are caused by the catheter irritating the bladder,
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had OAB. The number of people affected with OAB increases with age, thus it is expected that OAB will become more common in the future as the average age of people living in the
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If non-invasive and pharmacological approaches are not helpful, some people may be eligible for a surgical procedure to treat overactive bladder. Surgical options may include
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Stewart WF, Van Rooyen JB, Cundiff GW, Abrams P, Herzog AR, Corey R, Hunt TL, Wein AJ (May 2003). "Prevalence and burden of overactive bladder in the United States".
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Gormley EA, Lightner DJ, Faraday M, Vasavada SP (May 2015). "Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guideline amendment".
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10% of Caucasians and 19% of black people have a genetic difference which causes them to lack a certain enzyme. Lack of this enzyme makes the drug less effective.
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10% of Caucasians and 19% of black people have a genetic difference which causes them to lack a certain enzyme. Lack of this enzyme makes the drug less effective.
1102: 2435: 493:. If there is an underlying metabolic or pathologic condition that explains the symptoms, the symptoms may be considered part of that disease and not OAB. 485:, and ultrasound are generally not needed. Additionally, urine culture may be done to rule out infection. The frequency/volume chart may be maintained and 340:
The amount of urine passed during each urination is relatively small. Pain while urinating suggests that there is a problem other than overactive bladder.
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Urge incontinence can also be measured with pad tests, and these are often used for research purposes. Some people with urge incontinence also have
1406:"Drugs with anticholinergic effects and cognitive impairment, falls and all-cause mortality in older adults: A systematic review and meta-analysis" 3397: 56:
Several sections with inaccurate or outdated information; lack of compliance with Manual of Style; excessive inline citations; copyediting issues.
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Sacco E, et al. (2009). "Investigational drug therapies for overactive bladder syndrome: the potential alternatives to anticholinergics".
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Sacco E, Pinto F, Bassi P (April 2008). "Emerging pharmacological targets in overactive bladder therapy: experimental and clinical evidences".
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and causes urine to pass out of it. Both invasive and non-invasive electrical stimulation procedures may be used to treat overactive bladder.
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Anger JT, Le TX, Nissim HA, Rogo-Gupta L, Rashid R, Behniwal A, Smith AL, Litwin MS, Rodriguez LV, Wein AJ, Maliski SL (November 2012).
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Sacco E, Paolillo M, Totaro A, Pinto F, Volpe A, Gardi M, Bassi PF (2008). "Botulinum toxin in the treatment of overactive bladder".
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Diagnosis of OAB is made primarily on the person's signs and symptoms and by ruling out other possible causes such as an infection.
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One surgical intervention, called a cystoplasty, involves the enlargement of the bladder using tissue taken from the patient's
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The cause of OAB is usually unclear, and indeed there may be multiple causes. It is often associated with overactivity of the
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Sacco E, Bientinesi R (2012). "Future perspectives in pharmacological treatments options for overactive bladder syndrome".
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episodes, or who express a desire for medication along with therapy, may be treated with several classes of drugs, notably
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Araklitis G, Cardozo L (November 2017). "Safety issues associated with using medication to treat overactive bladder".
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to a degree that it negatively affects a person's life. The frequent need to urinate may occur during the day,
1366:"Use of free uroflowmetry vs pressure-flow studies in the diagnosis of overactive bladder syndrome in females" 1546:"Diagnosis and Treatment of Overactive Bladder (Non-Neurogenic) in Adults: AUA/SUFU Guideline Amendment 2019" 3126: 3013: 3005: 2884:
Sacco E, Bientinesi R, Marangi F, D'Addessi A, Racioppi M, Gulino G, Pinto F, Totaro A, Bassi P (2011). "".
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Tikkinen KA, Tammela TL, Rissanen AM, Valpas A, Huhtala H, Auvinen A (February 2007). Madersbacher S (ed.).
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Overactive bladder may be treated with electrical stimulation, which aims to reduce the contractions of the
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are generally not recommended. A diary to track problems can help determine whether treatments are working.
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Hutchinson, Alexander; Nesbitt, Alexander; Joshi, Andre; Clubb, Adrian; Perera, Marlon (Sep 2020).
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Medications are a common treatment option for people with overactive bladder syndrome. A number of
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Lightner, Deborah J.; Gomelsky, Alexander; Souter, Lesley; Vasavada, Sandip P. (September 2019).
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consumption, and drinking moderate fluids, can also have benefits. Medications, typically of the
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Sussman DO (September 2007). "Overactive bladder: treatment options in primary care medicine".
3553: 3513: 3318: 3100: 3085: 3023: 2901: 2855: 2785: 2739: 2691: 2673: 2600: 2557: 2495: 2458: 2407: 2368: 2311: 2274: 2248: 2240: 2191: 2183: 2134: 2107: 2020: 1938: 1899: 1804: 1786: 1747: 1709: 1665: 1629: 1575: 1567: 1520: 1495: 1435: 1386: 1365: 1339: 1333: 1314: 1258: 1252: 1209: 1158: 1103:"Diagnosis and Treatment of Overactive Bladder (Non-Neurogenic) in Adults: AUA/SUFU Guideline" 966: 727: 618:) are frequently used to treat overactive bladder. Long term use, however, has been linked to 486: 373: 313: 204: 119: 1514: 392:
Overactive bladder is characterized by a group of four symptoms: urgency, urinary frequency,
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Ouslander, Joseph; Reyes, Bernardo (2022). "Chapter 477: Caring for the Geriatric Patient".
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The cause of overactive bladder is unknown. Risk factors include obesity, caffeine, and
3496: 3492: 3226: 2850: 2815: 2686: 2653: 2363: 2338: 2102: 2077: 1894: 1869: 1624: 1599: 1490: 1458:"Electrical stimulation with non-implanted electrodes for overactive bladder in adults" 1457: 1430: 1405: 1309: 1284: 587: 571: 505: 1982: 1965: 536:, but when they occur together, the condition is usually known as mixed incontinence. 3580: 3141: 2964: 2781: 2612: 2507: 2015: 1998: 1002: 2913: 2797: 2751: 2569: 2323: 2032: 1950: 1721: 1363:
Nowakowski Ł, Futyma K, ZiΔ™tek A, Bogusiewicz M, GaΕ‚czyΕ„ski K, Rechberger T (2016).
3158: 3146: 3136: 1473: 1300: 908: 766: 686: 615: 549:. Patients who prove resistant to medications and therapy may then be treated with 490: 469:, although most people eventually adjust to the irritation and the spasms go away. 334: 309: 2307: 1782: 1257:(10 ed.). Philadelphia: Lippincott Williams & Wilkins. pp. 890–891. 3507: 2921: 2840: 1661: 1456:
Stewart F, Gameiro LF, El Dib R, Gameiro MO, Kapoor A, Amaro JL (December 2016).
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Coyne K, Schmier J, Hunt T, Corey R, Liberman J, Revicki D (March 2000).
1870:"Objective Evaluation of Overactive Bladder: Which Surveys Should I Use?" 1807:. MedlinePlus, the National Institutes of Health's Web site. 2010-03-09. 1705: 869: 851: 631: 619: 611: 458: 454: 413: 393: 360: 290: 2235: 2078:"How dry is "OAB-dry"? Perspectives from patients and physician experts" 453:
If bladder spasms occur or there is no urine in the drainage bag when a
285:) is a common condition where there is a frequent feeling of needing to 3240: 3065: 2430: 1934: 1615: 901:
less researched for safety and efficacy than Tolterodine and Oxybutynin
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less researched for safety and efficacy than Tolterodine and Oxybutynin
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less researched for safety and efficacy than Tolterodine and Oxybutynin
377: 286: 137: 124: 3441: 2170:. Medical and Advanced Surgical Management of Pelvic Floor Disorders. 1421: 3453: 3387: 3339: 2972: 1481: 1006: 1966:"PRN6: developing a specific HRQL instrument for overactive bladder" 2053:
Weill Cornell Medical College Department of Urology. Archived from
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Specific treatment is not always required. If treatment is desired
3529: 1999:"Lower urinary tract symptomatology: Its definition and confusion" 977: 557:(Botox) and other minimally-invasive surgical procedures, such as 520:
causes high frequency and volume, though not necessarily urgency.
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injury; over-consumption of water and caffeine; UTI; pelvic injury
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International Urogynecology Journal and Pelvic Floor Dysfunction
3195: 2936: 2211:"Overactive bladder syndrome: Management and treatment options" 1001:
Earlier reports estimated that about one in six adults in the
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OAB causes similar symptoms to some other conditions such as
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Campbell-Walsh Urology, Tenth Edition, Chapter 66, Page 1948
1600:"Symptom-based diagnosis of overactive bladder: an overview" 1338:. Rochester, MN: Mayo Clinic Scientific Press. p. 339. 841:
higher rates of constipation and dry mouth than tolterodine
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available as generic in places including the United States
441:, a pattern of bladder muscle contraction observed during 351:, and other behavioral methods are initially recommended. 744:
patch commonly causes skin irritation which can be severe
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States at US$ 12.6 billion and 4.2 billion Euro in 2000.
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Chancellor, Michael B; Christopher Smith (August 2011).
512:(BPH). Urinary tract infections often involve pain and 465:. Such spasms can be controlled with medication such as 209:
Based on symptoms after ruling out other possible causes
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Condition where a person has a frequent need to urinate
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Moro C, Uchiyama J, Chess-Williams R (December 2011).
429:'fear of leakage,' is an important concept to people. 2763: 2761: 1834:"Five Things Physicians and Patients Should Question" 3431: 1516:
Overactive bladder syndrome and urinary incontinence
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half the number of individuals as earlier reported.
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The Journal of the American Osteopathic Association
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available in market longer than other drugs for OAB
642:the majority, of patients with overactive bladder. 268: 258: 245: 226: 213: 203: 193: 181: 173: 165: 157: 147: 130: 118: 101: 96: 2168:Obstetrics and Gynecology Clinics of North America 1364: 942:in adults with neurological conditions, including 1519:. Oxford: Oxford University Press. pp. 7–8. 859:severe dry mouth less common than with oxybutynin 838:More effective for some symptoms than Tolterodine 2426:"FDA approves Botox for loss of bladder control" 2162:White, Nicola; Iglesia, Cheryl B. (2016-03-01). 1593: 1591: 1589: 1404:Ruxton K, Woodman RJ, Mangoni AA (August 2015). 741:lower rate of dry mouth as compared to pill form 2707: 2705: 2133:, Treasure Island (FL): StatPearls Publishing, 989:OAB is due to a different condition, such as a 919:, but does not require that enzyme to be active 815:fewer side effects than short-acting Oxybutynin 790:fewer side effects than short-acting Oxybutynin 763:fewer side effects than short-acting Oxybutynin 713:fewer side effects than short-acting Oxybutynin 681:more side effects than alternatives, including 1915: 1913: 1335:Mayo Clinic internal medicine concise textbook 3207: 2948: 2386:Diokno, Ananias; Ingber, Michael (Nov 2006). 938:Botulinum toxin A (Botox) is approved by the 922:it may avoid drug interactions of Tolterodine 675:many studies provide support of effectiveness 410:normal if consistent with the other factors. 8: 1733: 1731: 648:Comparison of overactive bladder medication 578:medications can keep the OAB under control. 1462:The Cochrane Database of Systematic Reviews 272:~40% of elderly adults, increasing with age 3432: 3214: 3200: 3192: 2955: 2941: 2933: 2271:Harrison's Principles of Internal Medicine 1096: 1094: 1092: 1090: 1088: 1086: 1084: 1082: 1080: 1078: 1076: 1074: 1072: 1070: 1068: 644: 425:and this can complicate clinical studies. 177:Age-related, or Secondary to other illness 110: 93: 2849: 2839: 2733: 2685: 2654:"Overactive bladder: A review and update" 2362: 2234: 2101: 2014: 1981: 1893: 1623: 1561: 1489: 1429: 1308: 1246: 1244: 1186: 1184: 1182: 1180: 1178: 1176: 1174: 1172: 1136: 1134: 1132: 1130: 1066: 1064: 1062: 1060: 1058: 1056: 1054: 1052: 1050: 1048: 769:applied to abdomen, arms, or thighs daily 79:Learn how and when to remove this message 2273:(21st ed.). New York: McGraw Hill. 1410:British Journal of Clinical Pharmacology 1101:American Urological Association (2014). 199:Old age, obesity, caffeine, constipation 2438:from the original on 24 September 2015. 2337:Sacco E, Bientinesi R (December 2012). 1604:Canadian Urological Association Journal 1289:Cochrane Database of Systematic Reviews 1044: 2215:Australian Journal of General Practice 553:interventions, such as treatment with 3117:Urologic chronic pelvic pain syndrome 2658:Experimental and Therapeutic Medicine 2388:"Oxybutynin in Detrusor Overactivity" 2264: 2262: 2157: 2155: 2153: 1451: 1449: 955:muscle that tenses around the bladder 925:little existing research on this drug 884:little existing research on this drug 775:little existing research on this drug 7: 2928:. U.S. National Library of Medicine. 2125:Harris, Shauna; Riggs, John (2024), 1254:Danforth's obstetrics and gynecology 691:severe dry mouth more often reported 372:into the bladder is another option. 1874:Current Bladder Dysfunction Reports 1846:, American Urogynecologic Society, 1028:National Association For Continence 25: 2392:Urologic Clinics of North America 1868:Shy M, Fletcher SG (March 2013). 1850:from the original on June 2, 2015 489:may be done to exclude tumor and 2865: 2782:10.1046/j.1464-410x.2001.02228.x 2016:10.1111/j.1442-2042.2007.01907.x 2003:International Journal of Urology 1533:from the original on 2016-03-05. 1371:Eur J Obstet Gynecol Reprod Biol 1352:from the original on 2016-03-05. 1271:from the original on 2016-03-05. 565:Lifestyle and behavioral therapy 34: 3251:Costovertebral angle tenderness 2343:Therapeutic Advances in Urology 1830:American Urogynecologic Society 1811:from the original on 2010-12-04 973:, or augmentation cystoplasty. 337:is also a good diagnostic aid. 136:Frequent feeling of needing to 3041:Neurogenic bladder dysfunction 1474:10.1002/14651858.CD010098.pub4 1301:10.1002/14651858.CD013519.pub2 417:as affecting quality of life. 264:Often but not always incurable 1: 3046:Bladder sphincter dyssynergia 2308:10.1080/14740338.2017.1376646 2296:Expert Opinion on Drug Safety 1983:10.1016/s1098-3015(11)70554-x 1783:10.1016/j.urology.2011.08.039 1228:"Urinary Bladder, Overactive" 241:, medications, Botox, surgery 3361:Lower urinary tract symptoms 2841:10.1371/journal.pone.0000195 2127:"Mixed Urinary Incontinence" 1662:10.1016/j.eururo.2009.03.080 1383:10.1016/j.ejogrb.2016.10.054 940:Food and Drug Administration 738:patch changed every 3–4 days 510:benign prostatic hyperplasia 237:, drinking moderate fluids, 1563:10.1097/JU.0000000000000309 534:stress urinary incontinence 449:Catheter-related irritation 105:Overactive bladder syndrome 54:. The specific problem is: 3603: 2597:10.1177/039156030907600301 2492:10.1177/039156030807500102 2451:Botulinum Toxin in Urology 2094:10.1016/j.juro.2012.07.044 1206:10.1016/j.juro.2012.09.079 1155:10.1016/j.juro.2015.01.087 694:user takes 2-3 pills a day 50:to meet Knowledge (XXG)'s 3587:Urinary bladder disorders 3079:Non-gonococcal urethritis 2726:10.1007/s00345-002-0301-4 2554:10.1007/s00192-007-0529-z 2404:10.1016/j.ucl.2006.06.003 2180:10.1016/j.ogc.2015.10.002 1886:10.1007/s11884-012-0167-2 1251:Gibbs, Ronald S. (2008). 647: 109: 3132:Retroperitoneal fibrosis 3051:Vesicointestinal fistula 2714:World Journal of Urology 2355:10.1177/1756287212457114 2227:10.31128/AJGP-11-19-5142 1997:Homma Y (January 2008). 1923:Quality of Life Research 669:well known by physicians 634:) may be used, as well. 327:urinary tract infections 3127:Urinary tract infection 1841:: an initiative of the 1598:Wein A (October 2011). 1332:Ghosh, Amit K. (2008). 991:urinary tract infection 502:urinary tract infection 331:neurological conditions 295:Loss of bladder control 221:neurological conditions 3383:Extravasation of urine 2670:10.3892/etm.2021.10879 2082:The Journal of Urology 1550:The Journal of Urology 1194:The Journal of Urology 1143:The Journal of Urology 971:sacral neuromodulation 624:Ξ²3 adrenergic receptor 559:sacral neuromodulation 439:detrusor urinae muscle 345:pelvic floor exercises 231:Pelvic floor exercises 215:Differential diagnosis 3056:Vesicoureteral reflux 3019:Interstitial cystitis 1513:Abrams, Paul (2011). 532:OAB is distinct from 3272:Urinary incontinence 3164:Urinary incontinence 3122:Obstructive uropathy 3034:Hemorrhagic cystitis 2922:"Overactive Bladder" 2898:10.5301/RU.2011.8886 2164:"Overactive Bladder" 2057:on 21 September 2013 2047:"Overactive Bladder" 1706:10.5301/RU.2012.8972 1692:Sacco E (2012). "". 1200:(6 Suppl): 2455–63. 312:. Poorly controlled 305:problems for years. 161:More common with age 61:improve this article 3297:Post-void dribbling 2832:2007PLoSO...2..195T 1805:"Urinary catheters" 1610:(Suppl 2): S135–6. 1033:Underactive bladder 915:same metabolite as 423:stress incontinence 322:chronic pelvic pain 318:functional mobility 254:drugs, Ξ²3 agonists 3540:External resources 3292:Nocturnal enuresis 3223:Signs and symptoms 3091:Urethral stricture 2996:Ureteric stricture 2434:. 24 August 2008. 2051:Cornell University 1935:10.1007/bf00451721 1616:10.5489/cuaj.11183 961:Invasive surgeries 948:spinal cord injury 944:multiple sclerosis 756:Topical medication 518:Diabetes insipidus 388:Signs and symptoms 279:Overactive bladder 97:Overactive bladder 3574: 3573: 3429: 3428: 3319:Urinary retention 3189: 3188: 3101:Urethral caruncle 3086:Urethral syndrome 2770:BJU International 2464:978-3-642-03579-1 2302:(11): 1273–1280. 1777:(6): 1442.e9–15. 1422:10.1111/bcp.12617 967:urinary diversion 931: 930: 728:transdermal patch 487:cystourethroscopy 407:Urinary frequency 374:Urinary catheters 355:in those who are 299:urge incontinence 276: 275: 205:Diagnostic method 91:Medical condition 89: 88: 81: 52:quality standards 43:This article may 16:(Redirected from 3594: 3433: 3282:Diurnal enuresis 3256:Vesical tenesmus 3225:relating to the 3216: 3209: 3202: 3193: 2963:Diseases of the 2957: 2950: 2943: 2934: 2929: 2917: 2871: 2870: 2869: 2863: 2853: 2843: 2811: 2802: 2801: 2765: 2756: 2755: 2737: 2709: 2700: 2699: 2689: 2648: 2642: 2641: 2639: 2638: 2623: 2617: 2616: 2580: 2574: 2573: 2537: 2531: 2530: 2518: 2512: 2511: 2475: 2469: 2468: 2446: 2440: 2439: 2422: 2416: 2415: 2383: 2377: 2376: 2366: 2334: 2328: 2327: 2291: 2285: 2284: 2266: 2257: 2256: 2238: 2206: 2200: 2199: 2159: 2148: 2147: 2146: 2145: 2122: 2116: 2115: 2105: 2073: 2067: 2066: 2064: 2062: 2043: 2037: 2036: 2018: 1994: 1988: 1987: 1985: 1961: 1955: 1954: 1917: 1908: 1907: 1897: 1865: 1859: 1858: 1857: 1855: 1826: 1820: 1819: 1817: 1816: 1801: 1795: 1794: 1762: 1756: 1755: 1735: 1726: 1725: 1689: 1683: 1680: 1674: 1673: 1650:European Urology 1644: 1638: 1637: 1627: 1595: 1584: 1583: 1565: 1541: 1535: 1534: 1510: 1504: 1503: 1493: 1453: 1444: 1443: 1433: 1401: 1395: 1394: 1368: 1360: 1354: 1353: 1329: 1323: 1322: 1312: 1279: 1273: 1272: 1248: 1239: 1238: 1236: 1234: 1224: 1218: 1217: 1188: 1167: 1166: 1138: 1125: 1124: 1122: 1120: 1115:on 26 April 2015 1114: 1108:. Archived from 1107: 1098: 874:extended release 808:extended release 706:extended release 645: 626:agonists (e.g., 547:anticholinergics 467:butylscopolamine 349:bladder training 333:to be excluded. 235:bladder training 114: 94: 84: 77: 73: 70: 64: 38: 37: 30: 21: 3602: 3601: 3597: 3596: 3595: 3593: 3592: 3591: 3577: 3576: 3575: 3570: 3569: 3535: 3534: 3444: 3430: 3425: 3411:Brewer infarcts 3392: 3349: 3323: 3260: 3229: 3220: 3190: 3185: 3105: 3096:Meatal stenosis 3060: 3000: 2967: 2961: 2920: 2883: 2880: 2875: 2874: 2864: 2813: 2812: 2805: 2767: 2766: 2759: 2711: 2710: 2703: 2650: 2649: 2645: 2636: 2634: 2631:www.nice.org.uk 2625: 2624: 2620: 2582: 2581: 2577: 2539: 2538: 2534: 2523:Eur Urol Review 2520: 2519: 2515: 2477: 2476: 2472: 2465: 2448: 2447: 2443: 2424: 2423: 2419: 2385: 2384: 2380: 2336: 2335: 2331: 2293: 2292: 2288: 2281: 2268: 2267: 2260: 2208: 2207: 2203: 2161: 2160: 2151: 2143: 2141: 2124: 2123: 2119: 2075: 2074: 2070: 2060: 2058: 2045: 2044: 2040: 1996: 1995: 1991: 1970:Value in Health 1963: 1962: 1958: 1919: 1918: 1911: 1867: 1866: 1862: 1853: 1851: 1843:ABIM Foundation 1839:Choosing Wisely 1832:(May 5, 2015), 1828: 1827: 1823: 1814: 1812: 1803: 1802: 1798: 1764: 1763: 1759: 1737: 1736: 1729: 1691: 1690: 1686: 1681: 1677: 1646: 1645: 1641: 1597: 1596: 1587: 1543: 1542: 1538: 1527: 1512: 1511: 1507: 1468:(2): CD010098. 1455: 1454: 1447: 1403: 1402: 1398: 1362: 1361: 1357: 1346: 1331: 1330: 1326: 1295:(9): CD013519. 1281: 1280: 1276: 1265: 1250: 1249: 1242: 1232: 1230: 1226: 1225: 1221: 1190: 1189: 1170: 1140: 1139: 1128: 1118: 1116: 1112: 1105: 1100: 1099: 1046: 1041: 1024: 1011:developed world 999: 986: 963: 936: 854:(short acting) 793:2 pills per day 785:(short-acting) 664:(short-acting) 584: 572:Kegel exercises 567: 555:botulinum toxin 542: 526: 475: 451: 435: 390: 370:botulinum toxin 365:anti-muscarinic 252:Anticholinergic 187:detrusor muscle 92: 85: 74: 68: 65: 58: 39: 35: 28: 23: 22: 15: 12: 11: 5: 3600: 3598: 3590: 3589: 3579: 3578: 3572: 3571: 3568: 3567: 3565:article/459340 3556: 3544: 3543: 3541: 3537: 3536: 3533: 3532: 3521: 3510: 3499: 3480: 3465: 3445: 3440: 3439: 3437: 3436:Classification 3427: 3426: 3424: 3423: 3418: 3413: 3408: 3402: 3400: 3394: 3393: 3391: 3390: 3385: 3380: 3379: 3378: 3373: 3368: 3357: 3355: 3351: 3350: 3348: 3347: 3342: 3337: 3331: 3329: 3325: 3324: 3322: 3321: 3316: 3315: 3314: 3309: 3304: 3299: 3294: 3289: 3284: 3279: 3268: 3266: 3262: 3261: 3259: 3258: 3253: 3248: 3243: 3237: 3235: 3231: 3230: 3227:urinary system 3221: 3219: 3218: 3211: 3204: 3196: 3187: 3186: 3184: 3183: 3182: 3181: 3176: 3171: 3161: 3156: 3155: 3154: 3149: 3144: 3134: 3129: 3124: 3119: 3113: 3111: 3107: 3106: 3104: 3103: 3098: 3093: 3088: 3083: 3082: 3081: 3070: 3068: 3062: 3061: 3059: 3058: 3053: 3048: 3043: 3038: 3037: 3036: 3031: 3026: 3024:Hunner's ulcer 3021: 3010: 3008: 3002: 3001: 2999: 2998: 2993: 2988: 2983: 2977: 2975: 2969: 2968: 2962: 2960: 2959: 2952: 2945: 2937: 2931: 2930: 2918: 2888:(in Italian). 2879: 2878:External links 2876: 2873: 2872: 2803: 2757: 2701: 2643: 2633:. 2 April 2019 2618: 2591:(3): 161–177. 2575: 2532: 2513: 2470: 2463: 2441: 2417: 2398:(4): 439–445. 2378: 2329: 2286: 2280:978-1264268504 2279: 2258: 2221:(9): 593–598. 2201: 2149: 2117: 2068: 2038: 1989: 1956: 1929:(5): 291–306. 1909: 1860: 1821: 1796: 1757: 1727: 1684: 1675: 1639: 1585: 1556:(3): 558–563. 1536: 1525: 1505: 1445: 1396: 1355: 1344: 1324: 1274: 1263: 1240: 1219: 1168: 1149:(5): 1572–80. 1126: 1043: 1042: 1040: 1037: 1036: 1035: 1030: 1023: 1020: 998: 995: 985: 982: 962: 959: 935: 932: 929: 928: 927: 926: 923: 920: 911: 905: 904: 903: 902: 899: 898:1 pill per day 894: 888: 887: 886: 885: 882: 881:1 pill per day 877: 866: 865: 864: 863: 860: 855: 848: 847: 846: 845: 842: 839: 836: 835:1 pill per day 831: 825: 824: 823: 822: 819: 818:1 pill per day 816: 811: 800: 799: 798: 797: 794: 791: 786: 779: 778: 777: 776: 773: 770: 764: 759: 748: 747: 746: 745: 742: 739: 736: 731: 720: 719: 718: 717: 716:1 pill per day 714: 709: 698: 697: 696: 695: 692: 689: 679: 676: 673: 670: 665: 658: 657: 654: 650: 649: 588:antimuscarinic 583: 580: 566: 563: 541: 538: 525: 524:Classification 522: 506:bladder cancer 474: 471: 450: 447: 434: 431: 389: 386: 274: 273: 270: 266: 265: 262: 256: 255: 249: 243: 242: 228: 224: 223: 217: 211: 210: 207: 201: 200: 197: 191: 190: 183: 179: 178: 175: 171: 170: 167: 163: 162: 159: 155: 154: 151: 145: 144: 134: 128: 127: 122: 116: 115: 107: 106: 103: 99: 98: 90: 87: 86: 42: 40: 33: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 3599: 3588: 3585: 3584: 3582: 3566: 3562: 3561: 3557: 3555: 3551: 3550: 3546: 3545: 3542: 3538: 3531: 3527: 3526: 3522: 3520: 3516: 3515: 3511: 3509: 3505: 3504: 3500: 3498: 3494: 3490: 3489: 3485: 3481: 3479: 3475: 3474: 3470: 3466: 3464: 3460: 3456: 3455: 3451: 3447: 3446: 3443: 3438: 3434: 3422: 3419: 3417: 3414: 3412: 3409: 3407: 3404: 3403: 3401: 3399: 3395: 3389: 3386: 3384: 3381: 3377: 3374: 3372: 3369: 3367: 3364: 3363: 3362: 3359: 3358: 3356: 3352: 3346: 3343: 3341: 3338: 3336: 3333: 3332: 3330: 3326: 3320: 3317: 3313: 3310: 3308: 3305: 3303: 3300: 3298: 3295: 3293: 3290: 3288: 3285: 3283: 3280: 3278: 3275: 3274: 3273: 3270: 3269: 3267: 3263: 3257: 3254: 3252: 3249: 3247: 3244: 3242: 3239: 3238: 3236: 3232: 3228: 3224: 3217: 3212: 3210: 3205: 3203: 3198: 3197: 3194: 3180: 3177: 3175: 3172: 3170: 3167: 3166: 3165: 3162: 3160: 3157: 3153: 3150: 3148: 3145: 3143: 3142:Bladder stone 3140: 3139: 3138: 3135: 3133: 3130: 3128: 3125: 3123: 3120: 3118: 3115: 3114: 3112: 3108: 3102: 3099: 3097: 3094: 3092: 3089: 3087: 3084: 3080: 3077: 3076: 3075: 3072: 3071: 3069: 3067: 3063: 3057: 3054: 3052: 3049: 3047: 3044: 3042: 3039: 3035: 3032: 3030: 3027: 3025: 3022: 3020: 3017: 3016: 3015: 3012: 3011: 3009: 3007: 3003: 2997: 2994: 2992: 2989: 2987: 2984: 2982: 2979: 2978: 2976: 2974: 2970: 2966: 2965:urinary tract 2958: 2953: 2951: 2946: 2944: 2939: 2938: 2935: 2927: 2923: 2919: 2915: 2911: 2907: 2903: 2899: 2895: 2892:(4): 241–56. 2891: 2887: 2882: 2881: 2877: 2868: 2861: 2857: 2852: 2847: 2842: 2837: 2833: 2829: 2825: 2821: 2817: 2810: 2808: 2804: 2799: 2795: 2791: 2787: 2783: 2779: 2775: 2771: 2764: 2762: 2758: 2753: 2749: 2745: 2741: 2736: 2735:2027.42/42170 2731: 2727: 2723: 2720:(6): 327–36. 2719: 2715: 2708: 2706: 2702: 2697: 2693: 2688: 2683: 2679: 2675: 2671: 2667: 2663: 2659: 2655: 2647: 2644: 2632: 2628: 2622: 2619: 2614: 2610: 2606: 2602: 2598: 2594: 2590: 2586: 2579: 2576: 2571: 2567: 2563: 2559: 2555: 2551: 2548:(4): 583–98. 2547: 2543: 2536: 2533: 2529:(2): 120–126. 2528: 2524: 2517: 2514: 2509: 2505: 2501: 2497: 2493: 2489: 2485: 2481: 2474: 2471: 2466: 2460: 2456: 2452: 2445: 2442: 2437: 2433: 2432: 2427: 2421: 2418: 2413: 2409: 2405: 2401: 2397: 2393: 2389: 2382: 2379: 2374: 2370: 2365: 2360: 2356: 2352: 2349:(6): 315–24. 2348: 2344: 2340: 2333: 2330: 2325: 2321: 2317: 2313: 2309: 2305: 2301: 2297: 2290: 2287: 2282: 2276: 2272: 2265: 2263: 2259: 2254: 2250: 2246: 2242: 2237: 2232: 2228: 2224: 2220: 2216: 2212: 2205: 2202: 2197: 2193: 2189: 2185: 2181: 2177: 2173: 2169: 2165: 2158: 2156: 2154: 2150: 2140: 2136: 2132: 2128: 2121: 2118: 2113: 2109: 2104: 2099: 2095: 2091: 2088:(5): 1811–5. 2087: 2083: 2079: 2072: 2069: 2056: 2052: 2048: 2042: 2039: 2034: 2030: 2026: 2022: 2017: 2012: 2008: 2004: 2000: 1993: 1990: 1984: 1979: 1975: 1971: 1967: 1960: 1957: 1952: 1948: 1944: 1940: 1936: 1932: 1928: 1924: 1916: 1914: 1910: 1905: 1901: 1896: 1891: 1887: 1883: 1879: 1875: 1871: 1864: 1861: 1849: 1845: 1844: 1840: 1835: 1831: 1825: 1822: 1810: 1806: 1800: 1797: 1792: 1788: 1784: 1780: 1776: 1772: 1768: 1761: 1758: 1753: 1749: 1746:(9): 379–85. 1745: 1741: 1734: 1732: 1728: 1723: 1719: 1715: 1711: 1707: 1703: 1699: 1695: 1688: 1685: 1679: 1676: 1671: 1667: 1663: 1659: 1656:(3): 488–96. 1655: 1651: 1643: 1640: 1635: 1631: 1626: 1621: 1617: 1613: 1609: 1605: 1601: 1594: 1592: 1590: 1586: 1581: 1577: 1573: 1569: 1564: 1559: 1555: 1551: 1547: 1540: 1537: 1532: 1528: 1526:9780199599394 1522: 1518: 1517: 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