437:
243:
554:
159:
140:
40:
589:
719:) of early stage borderline tumors have been estimated to result in chance of over 50% of spontaneous pregnancy with a low risk of lethal recurrence of the tumor (0.5%). On the other hand, in cases of conservative treatment in advanced stage borderline tumors, spontaneous pregnancy rates have been estimated to be 35% and the risk of lethal recurrence 2%.
606:
are uncommon surface-epithelial stromal cell tumors in which the epithelial cell (which defines these tumors) is a transitional cell. These are similar in appearance to bladder epithelia. The tumors may be very small to very large, and may be solid or cystic. Histologically, the tumor consists of
514:
account for approximately 20% of all ovarian cancers and are mostly malignant (endometrioid carcinomas). They are made of tubular glands bearing a close resemblance to benign or malignant endometrium. 15-30% of endometrioid carcinomas occur in individuals with carcinoma of the endometrium, and these
628:
Small cell tumours are rare and aggressive, they contribute to less than 2% of all gynaecologic malignancies. The average age of diagnosis is 24 years old, and the majority of patients also present with hypercalcemia (62%). It typically present with a unilateral large tumor. Most women die within a
571:
are characterized by large epithelial cells with abundant clear cytoplasm and may be seen in association with endometriosis or endometrioid carcinoma of the ovary, bearing a resemblance to clear cell carcinoma of the endometrium. They may be predominantly solid or cystic. If solid, the clear cells
644:
Research suggests that in the first line treatment of
Endometrial Ovarian Cancer (EOC), Pegylated Liposomal Doxorubicin paired with Carboplatin is a satisfactory alternative to Paclitaxel with Carboplatin. In people with platinum-sensitive relapsed EOC, research has found that Pegylated Liposomal
130:
is often elevated but is only 50% accurate so it is not a useful tumor marker to assess the progress of treatment. 75% of women with epithelial ovarian cancer are found within the advanced-stages; however younger patients are more likely to have better prognoses than older patients.
544:
Prognosis again is dependent on the spread of the tumor, as well as how differentiated the tumor appears. The overall prognosis is somewhat worse than for serous or mucinous tumors, and the 5-year survival rate for patients with tumors confined to the ovary is approximately 75%.
1458:
1439:
498:
contained within the ovary, malignant tumors without invasion, and invasive malignant tumors are greater than 95%, 90%, and 66%, respectively. One rare but noteworthy condition associated with mucinous ovarian neoplasms is
477:
with apical mucin and the absence of cilia, similar in appearance with benign cervical or intestinal epithelia. The appearance can look similar to colonic or ovarian cancer, but typically originates from the appendix (see
440:
Histopathology of lining of a benign mucinous tumor of the ovary. Benign mucinous ovarian tumors consist of simple, nonstratified columnar epithelium with basally-located hyperchromatic nuclei and resemble gastric foveolar
784:
Rauh-Hain JA, Foley O, Winograd D, Andrade C, Clark RM, Vargas RJ, et al. Clinical characteristics and outcomes of pa- tients with stage I epithelial ovarian cancer compared to fallo- pian tube cancer. Am J Obstet
Gynecol
1310:
Kolomainen DF, Larkin JM, Badran M, A'Hern RP, King DM, Fisher C, et al. (February 2002). "Epithelial ovarian cancer metastasizing to the brain: a late manifestation of the disease with an increasing incidence".
607:
nests of the aforementioned transitional cells within surrounding tissue that resembles normal ovary. Brenner tumors may be benign or malignant, depending on whether the tumor cells invade the surrounding tissue.
857:
Ghezzi F, Cromi A, Fanfani F, Malzoni M, Ditto A, De Iaco P, et al. Laparoscopic fertility-sparing surgery for early ovarian epithelial cancer: a multi-institutional experience. Gynecol On- col 2016;141:461–5.
515:
patients have a better prognosis. They appear similar to other surface epithelial-stromal tumors, with solid and cystic areas. 40% of these tumors are bilateral, when bilateral, metastases is often present.
246:
Histopathology of lining of a benign serous tumor of the ovary. Benign serous ovarian tumors are thin walled unilocular cysts that are lined by ciliated pseudostratified cuboidal or columnar epithelium.
580:
These tumors tend to be aggressive, the five year survival rate for tumors confined to the ovaries is approximately 65%. If the tumor has spread beyond the ovary at diagnosis, the prognosis is poor
875:
Kashima K, Yahata T, Fujita K, Tanaka K. Outcomes of fertility-sparing surgery for women of reproductive age with FIGO stage IC epithelial ovarian cancer. Int J Gynaecol Obstet 2013;121:53–5.
775:
Kashima K, Yahata T, Fujita K, Tanaka K. Outcomes of fertility-sparing surgery for women of reproductive age with FIGO stage IC epithelial ovarian cancer. Int J Gynaecol Obstet 2013;121:53–5.
503:. As primary ovarian mucinous tumors are usually unilateral (in one ovary), the presentation of bilateral mucinous tumors requires exclusion of a non-ovarian origin, usually the appendix.
866:
Melamed A, Keating NL, Clemmer JT, Bregar AJ, Wright JD, Boruta DM, et al. Laparoscopic staging for apparent stage I epithelial ovarian cancer. Am J Obstet
Gynecol 2017;216:50. e1–50.e12.
1533:
794:
Wright JD, Shah M, Mathew L, Burke WM, Culhane J, Gold- man N, et al. Fertility preservation in young women with epi- thelial ovarian cancer. Cancer 2009;115:4118–26.
1397:
762:
Centers for
Disease Control and Prevention, CDC WONDER. United States and Puerto Rico cancer statistics, 1999–2013 inci- dence incidence request.Available at:
533:
Carcinomas (malignant tumors) have invasive glands with crowded, atypical cells, frequent mitoses. With poorer differentiation, the tumor becomes more solid.
428:
While the 5-year survival rates of borderline tumors are excellent, this should not be seen as evidence of cure, as recurrences can occur many years later.
1897:
126:; however is mainly only found in postmenopausal women with the exception of the United States where 7% of cases occur in women under the age of 40. Serum
1973:
1882:
1288:
1526:
458:
In some cases mucinous tumors are characterized by more cysts of variable size and a rarity of surface involvement as compared to serous tumors
436:
461:
Also in comparison to serous tumors, mucinous tumors are less frequently bilateral, approximately 5% of primary mucinous tumors are bilateral.
1963:
1854:
1407:
1074:
833:
425:
and malignant tumors confined to the ovaries are 100% and 70% respectively. If the peritoneum is involved, these rates become 90% and 25%.
242:
1691:
1653:
1892:
1609:
884:
Melamed A., Rizzo A.E., Nitecki R., et al All-cause mortality after fertility-sparing surgery for stage i epithelial ovarian cancer.
803:
Melamed A., Rizzo A.E., Nitecki R., et al All-cause mortality after fertility-sparing surgery for stage i epithelial ovarian cancer.
711:
subsequent to treatment of surface epithelial-stromal tumors depends mainly on histology and initial staging to separate it into early
1877:
1978:
1920:
1519:
1353:"Fertility and borderline ovarian tumor: a systematic review of conservative management, risk of recurrence and alternative options"
1124:
553:
310:
of the tumor increases with the amount of solid areas present, including both papillary structures and any necrotic tissue present.
1003:
Baradwan, Saeed; Alalyani, Haneen; Baradwan, Amira; Baradwan, Afnan; Al-Ghamdi, Maram; Alnemari, Jameel; Al-Jaroudi, Dania (2018).
2021:
411:
in particular with serous malignancies, the presence of malignant spread to the peritoneum is important with regard to prognosis.
2016:
1671:
2047:
163:
1859:
1634:
1572:
158:
715:(or more benign) versus advanced stages of borderline (or more malignant). Conservative management (without bilateral
848:
Smedley H, Sikora K. Age as a prognostic factor in epithelial ovarian carcinoma. Br J Obstet
Gynaecol 2016;92:839–42.
1194:
Lawrie TA, Rabbie R, Thoma C, Morrison J, et al. (The
Cochrane Collaboration) (October 2013). Lawrie TA (ed.).
749:
SEER Survival
Monograph: Cancer Survival Among Adults: US SEER Program, 1988-2001, Patient and Tumor Characteristics
1594:
139:
100:
2026:
649:
568:
279:, accounts for approximately 40% of all carcinomas of the ovary and are the most common malignant ovarian tumors.
221:
1849:
1477:
572:
tend to be arranged in sheets or tubules. In the cystic variety, the neoplastic cells make up the cyst lining.
147:
1941:
2001:
1887:
479:
418:
1724:
665:
500:
483:
403:
a moderately differentiated tumor usually resembles the cell type of origin, but appears frankly malignant
2011:
1777:
1681:
1296:
205:(evidence of malignancy and stromal invasion). Borderline tumors are of uncertain malignant potential.
943:"Malignant Transformation in a Mature Teratoma with Metastatic Deposits in the Omentum: A Case Report"
1599:
285:
Malignant serous tumors occur later in life on average, although somewhat earlier in familial cases.
170:
are labeled in center of the main diagram, and represent all types except the ones separated at top.
162:
Ovarian cancers in women aged 20+, with area representing relative incidence and color representing
1719:
1666:
1462:
1089:
228:(transitional cell) tumors, though there are a few mixed, undifferentiated and unclassified types.
39:
288:
20% of benign, 30% of borderline, and 66% of malignant tumors are bilateral (affect both ovaries).
1968:
1844:
1836:
1661:
1629:
1604:
708:
511:
363:
invasion of surrounding ovarian stroma (whether or not cells are infiltrating surrounding tissue)
276:
217:
1763:
1289:"NCI Issues Clinical Announcement for Preferred Method of Treatment for Advanced Ovarian Cancer"
1092:. Retrieved June 2014. By Lee-Jones, L. Atlas Genet Cytogenet Oncol Haematol. 2004;8(2):115-133.
618:
are generally classified into epithelial tumors associated with distinctive endocrine features.
740:
1785:
1546:
1403:
1374:
1328:
1270:
1221:
1176:
1120:
1070:
1042:
1024:
982:
964:
929:
829:
64:
1616:
1554:
1364:
1320:
1260:
1252:
1211:
1203:
1166:
1158:
1112:
1032:
1016:
972:
954:
919:
889:
808:
752:. Vol. NIH Pub. No. 07-6215. Bethesda, MD: National Cancer Institute. pp. 133–144.
712:
495:
486:). Clear stromal invasion is used to differentiate borderline tumors from malignant tumors.
422:
366:
262:
198:
1936:
1915:
1869:
1816:
1755:
1743:
1714:
1701:
661:
179:
175:
1511:
1090:
Atlas of
Genetics and Cytogenetics in Oncology and Haematology - Ovary: Epithelial tumors
17:
1955:
1821:
1799:
1729:
1639:
1563:
1265:
1240:
1216:
1196:"Pegylated liposomal doxorubicin for first-line treatment of epithelial ovarian cancer"
1195:
1171:
1146:
1037:
1004:
977:
942:
689:
638:
592:
445:
348:
213:
151:
123:
115:
52:
2041:
1993:
1983:
1738:
645:
Doxorubicin with
Carboplatin is a better treatment than Paclitaxel with Carboplatin.
603:
373:
225:
143:
1471:
1467:
939:- Minor adjustment for mature cystic teratomas (0.17 to 2% risk of ovarian cancer):
357:
the division between benign, borderline, and malignant is ascertained by assessing:
251:
These tumors vary in size from small and nearly imperceptible to large, filling the
183:
1709:
1256:
1207:
716:
653:
237:
209:
596:
561:
56:
1482:
1147:"A case of small cell carcinoma of the ovary hypercalcemic variant in a teenager"
893:
812:
747:
282:
Benign and borderline tumors are most common between the ages of 20 and 50 years.
1162:
657:
111:
1496:
1116:
1053:
1826:
1808:
1324:
685:
621:
The World Health
Organisation (WHO) recognises SCCO as two distinct entities:
588:
557:
345:
323:
307:
187:
104:
48:
1501:
1028:
968:
933:
464:
May form very large cystic masses, with recorded weights exceeding 25 kg
400:
a poorly differentiated tumor may not resemble the cell type of origin at all
1452:
1448:
1369:
1352:
1107:
Kaphan AA, Castro CM (2014-01-01). MPH rG, FRCPATH RH, MD JO, MD MJ (eds.).
266:
252:
202:
190:
92:
1378:
1332:
1274:
1225:
1180:
1046:
986:
924:
907:
530:
Borderline tumors have a complex branching pattern without stromal invasion
959:
108:
2006:
1907:
1734:
669:
320:
96:
84:
69:
1507:
Small Cell Ovarian Cancer Research Collaboration & Patients Registry
1431:
1241:"Pegylated liposomal doxorubicin for relapsed epithelial ovarian cancer"
746:. In Baguio RN, Young JL, Keel GE, Eisner MP, Lin YD, Horner MJ (eds.).
1686:
1676:
455:
Somewhat less common, accounting for about 25% of all ovarian neoplasms
452:
Closely resemble their serous counterparts but unlikely to be bilateral
81:
1020:
1005:"Bilateral ovarian masses with different histopathology in each ovary"
1443:
673:
337:
330:
258:
194:
127:
88:
269:
types of serous tumors account for about 30% of all ovarian tumors.
1542:
1054:
Creative Commons Attribution 4.0 International (CC BY 4.0) license
824:
Bradshaw KD, Schorge JO, Schaffer J, Lisa M H, Hoffman BG (2008).
693:
587:
552:
435:
387:
The prognosis of a serous tumor, like most neoplasms, depends on
241:
1351:
DaraĂŻ E, Fauvet R, Uzan C, Gouy S, Duvillard P, Morice P (2012).
272:
75% are benign or of borderline malignancy, and 25% are malignant
193:
features determine whether a surface epithelial-stromal tumor is
1239:
Lawrie TA, Bryant A, Cameron A, Gray E, Morrison J (July 2013).
697:
684:
For surface epithelial-stromal tumors, the most common sites of
341:
1515:
524:
Glands bearing a strong resemblance to endometrial-type glands
376:
are a characteristic microscopic finding of cystadenocarcinomas
360:
cellular atypia (whether or not individual cells look abnormal)
122:. This group of tumors accounts for 90% to 95% of all cases of
527:
Benign tumors have mature-appearing glands in a fibrous stroma
369:
may have cellular atypia but do NOT have evidence of invasion
174:
Epithelial-stromal tumors are classified on the basis of the
908:"Spectrum of ovarian tumors in a referral hospital in Nepal"
1065:
Cotran RS, Kumar V, Nelson F, Robbins SL, Abbas AK (2005).
397:
a well-differentiated tumor closely resembles benign tumors
1506:
763:
625:
and Small Cell Ovarian Cancer of Pulmonary Type (SCCOPT).
622:
615:
394:
this is how closely the tumor cells resemble benign cells
623:
Small Cell Ovarian Cancer of Hypercalcemic Type (SCCOHT)
186:
processes, and the location of the epithelial elements.
344:
fluid has come to be describe the particular type of
1421:
118:(tubal) tissue. Tumors of this type are also called
1992:
1954:
1929:
1906:
1868:
1835:
1807:
1798:
1776:
1754:
1700:
1652:
1587:
1571:
1562:
1553:
1425:
63:
32:
1109:Small Cell and Neuroendocrine Cancers of the Ovary
1069:(7th ed.). St. Louis, Mo: Elsevier Saunders.
473:Mucinous tumors are characterized by a lining of
99:in this group are thought to be derived from the
1140:
1138:
1136:
1111:. John Wiley & Sons, Ltd. pp. 139–147.
906:Vaidya, SA; Kc, S; Sharma, P; Vaidya, S (2014).
154:, with surface epithelial-stromal tumors at top.
998:
996:
1067:Robbins and Cotran pathologic basis of disease
766:cancer-v2013.html. Retrieved December 1, 2016.
734:
732:
648:For advanced cancer of this histology, the US
55:, a type of surface epithelial-stromal tumor.
1527:
178:type, the relative amounts of epithelium and
8:
1502:Diagram: "Epithelial Stromal Ovarian Tumors"
1346:
1344:
1342:
1202:(10). John Wiley & Sons, Ltd: CD010482.
941:Mandal, Shramana; Badhe, Bhawana A. (2012).
1245:The Cochrane Database of Systematic Reviews
1200:The Cochrane Database of Systematic Reviews
1804:
1584:
1568:
1559:
1534:
1520:
1512:
1497:Johns Hopkins: "Surface Epithelial Tumors"
1422:
1399:Harrison's principles of internal medicine
38:
29:
1368:
1264:
1215:
1170:
1036:
976:
958:
923:
340:which originated as a description of the
1402:(15th ed.). New York: McGraw-Hill.
157:
138:
1974:Clear-cell adenocarcinoma of the vagina
728:
408:extension of tumor to other structures
1964:Squamous-cell carcinoma of the vagina
1855:Endometrial intraepithelial neoplasia
1145:Bakhru A, Liu JR, Lagstein A (2012).
1102:
1100:
1098:
7:
1692:Sex cord tumour with annular tubules
560:of an ovarian clear cell carcinoma.
354:may involve the surface of the ovary
1610:Papillary serous cystadenocarcinoma
1878:Cervical intraepithelial neoplasia
1850:Uterine papillary serous carcinoma
741:"Chapter 16: Cancers of the Ovary"
637:For more general information, see
275:The malignant form of this tumor,
25:
1979:Vaginal intraepithelial neoplasia
1921:Gestational trophoblastic disease
1151:Gynecologic Oncology Case Reports
168:Surface epithelial-stromal tumors
78:Surface epithelial-stromal tumors
2022:Vulvar intraepithelial neoplasia
664:(IP) administration. Preferred
616:Small cell ovarian cancer (SCCO)
33:Surface epithelial-stromal tumor
1295:. January 2006. Archived from
1257:10.1002/14651858.cd006910.pub2
1208:10.1002/14651858.cd010482.pub2
475:tall columnar epithelial cells
1:
1898:Villoglandular adenocarcinoma
912:Journal of Pathology of Nepal
164:5-year relative survival rate
2017:Extramammary Paget's disease
1860:Uterine clear-cell carcinoma
1635:Ovarian clear-cell carcinoma
1313:Journal of Clinical Oncology
894:10.1097/AOG.0000000000002102
828:. McGraw-Hill Professional.
813:10.1097/AOG.0000000000002102
1163:10.1016/j.gynor.2012.09.001
494:10-year survival rates for
302:predominantly fibrous areas
2064:
1817:Uterine fibroids/leiomyoma
1672:Sertoli–Leydig cell tumour
1595:Ovarian serous cystadenoma
1117:10.1002/9781118655344.ch12
391:degree of differentiation
235:
101:ovarian surface epithelium
2027:Bartholin gland carcinoma
1969:Botryoid rhabdomyosarcoma
1625:
1357:Human Reproduction Update
1325:10.1200/JCO.2002.20.4.982
1293:National Cancer Institute
947:Case Reports in Pathology
650:National Cancer Institute
319:lined by tall, columnar,
277:serous cystadenocarcinoma
46:
37:
1654:Sex cord–gonadal stromal
1573:Glandular and epithelial
482:with clinical condition
299:cystic and fibrous areas
292:Components can include:
18:Borderline ovarian tumor
666:chemotherapeutic agents
652:recommends a method of
480:mucinous adenocarcinoma
419:five-year survival rate
208:This group consists of
1725:Endodermal sinus tumor
925:10.3126/jpn.v4i7.10295
764:http://wonder.cdc.gov/
600:
565:
501:pseudomyxoma peritonei
484:Pseudomyxoma peritonei
442:
247:
171:
155:
120:ovarian adenocarcinoma
2048:Gynaecological cancer
2012:Papillary hidradenoma
1942:Mixed MĂĽllerian tumor
1893:Glassy-cell carcinoma
1682:Granulosa cell tumour
1370:10.1093/humupd/dms047
1009:Clinical Case Reports
591:
556:
439:
245:
161:
142:
1883:Clear-cell carcinoma
1600:Mucinous cystadenoma
1396:Braunwald E (2001).
826:Williams' Gynecology
351:seen in these tumors
1720:Embryonal carcinoma
1667:Sertoli cell tumour
1578:surface epithelial-
1299:on 13 January 2009.
960:10.1155/2012/568062
888:2017;130(1):71-79.
807:2017;130(1):71-79.
704:Effect on fertility
629:year of diagnosis.
512:Endometrioid tumors
507:Endometrioid tumors
47:High magnification
1845:Endometrioid tumor
1662:Leydig cell tumour
1630:Endometrioid tumor
1605:Cystadenocarcinoma
785:2015;212:600.e1–8.
739:Kosary CL (2007).
601:
566:
443:
329:filled with clear
248:
182:, the presence of
172:
156:
2035:
2034:
1950:
1949:
1794:
1793:
1786:Adenomatoid tumor
1772:
1771:
1648:
1647:
1547:urogenital system
1492:
1491:
1409:978-0-07-913686-2
1076:978-0-7216-0187-8
1021:10.1002/ccr3.1466
886:Obstet. Gynecol..
835:978-0-07-147257-9
805:Obstet. Gynecol..
611:Small cell tumors
569:Clear cell tumors
549:Clear cell tumors
496:borderline tumors
423:borderline tumors
367:borderline tumors
75:
74:
27:Medical condition
16:(Redirected from
2055:
1805:
1715:Nongerminomatous
1617:Krukenberg tumor
1585:
1569:
1560:
1536:
1529:
1522:
1513:
1423:
1413:
1383:
1382:
1372:
1348:
1337:
1336:
1307:
1301:
1300:
1285:
1279:
1278:
1268:
1236:
1230:
1229:
1219:
1191:
1185:
1184:
1174:
1142:
1131:
1130:
1104:
1093:
1087:
1081:
1080:
1062:
1056:
1050:
1040:
1000:
991:
990:
980:
962:
937:
927:
902:
896:
882:
876:
873:
867:
864:
858:
855:
849:
846:
840:
839:
821:
815:
801:
795:
792:
786:
782:
776:
773:
767:
760:
754:
753:
745:
736:
372:the presence of
199:borderline tumor
42:
30:
21:
2063:
2062:
2058:
2057:
2056:
2054:
2053:
2052:
2038:
2037:
2036:
2031:
1988:
1946:
1937:Uterine sarcoma
1925:
1916:Choriocarcinoma
1902:
1864:
1831:
1790:
1768:
1764:Meigs' syndrome
1750:
1744:Choriocarcinoma
1696:
1644:
1621:
1579:
1576:
1549:
1540:
1493:
1488:
1487:
1434:
1420:
1410:
1395:
1392:
1387:
1386:
1350:
1349:
1340:
1309:
1308:
1304:
1287:
1286:
1282:
1251:(7): CD006910.
1238:
1237:
1233:
1193:
1192:
1188:
1144:
1143:
1134:
1127:
1106:
1105:
1096:
1088:
1084:
1077:
1064:
1063:
1059:
1051:
1002:
1001:
994:
940:
938:
905:
903:
899:
883:
879:
874:
870:
865:
861:
856:
852:
847:
843:
836:
823:
822:
818:
802:
798:
793:
789:
783:
779:
774:
770:
761:
757:
743:
738:
737:
730:
725:
706:
696:(26%), and the
682:
662:intraperitoneal
635:
613:
586:
578:
551:
542:
521:
509:
492:
471:
446:Mucinous tumors
434:
432:Mucinous tumors
385:
374:psammoma bodies
316:
240:
234:
176:epithelial cell
137:
80:are a class of
28:
23:
22:
15:
12:
11:
5:
2061:
2059:
2051:
2050:
2040:
2039:
2033:
2032:
2030:
2029:
2024:
2019:
2014:
2009:
2004:
1998:
1996:
1990:
1989:
1987:
1986:
1981:
1976:
1971:
1966:
1960:
1958:
1952:
1951:
1948:
1947:
1945:
1944:
1939:
1933:
1931:
1927:
1926:
1924:
1923:
1918:
1912:
1910:
1904:
1903:
1901:
1900:
1895:
1890:
1885:
1880:
1874:
1872:
1866:
1865:
1863:
1862:
1857:
1852:
1847:
1841:
1839:
1833:
1832:
1830:
1829:
1824:
1822:Leiomyosarcoma
1819:
1813:
1811:
1802:
1796:
1795:
1792:
1791:
1789:
1788:
1782:
1780:
1778:Fallopian tube
1774:
1773:
1770:
1769:
1767:
1766:
1760:
1758:
1752:
1751:
1749:
1748:
1747:
1746:
1741:
1732:
1730:Gonadoblastoma
1727:
1722:
1712:
1706:
1704:
1698:
1697:
1695:
1694:
1689:
1684:
1679:
1674:
1669:
1664:
1658:
1656:
1650:
1649:
1646:
1645:
1643:
1642:
1640:Brenner tumour
1637:
1632:
1626:
1623:
1622:
1620:
1619:
1614:
1613:
1612:
1602:
1597:
1591:
1589:
1582:
1566:
1557:
1551:
1550:
1545:of the female
1541:
1539:
1538:
1531:
1524:
1516:
1510:
1509:
1504:
1499:
1490:
1489:
1486:
1485:
1474:
1455:
1435:
1430:
1429:
1427:
1426:Classification
1419:
1418:External links
1416:
1415:
1414:
1408:
1391:
1388:
1385:
1384:
1338:
1302:
1280:
1231:
1186:
1132:
1125:
1094:
1082:
1075:
1057:
1015:(5): 784–787.
992:
918:(7): 539–543.
897:
877:
868:
859:
850:
841:
834:
816:
796:
787:
777:
768:
755:
727:
726:
724:
721:
705:
702:
690:pleural cavity
681:
678:
656:that combines
639:ovarian cancer
634:
631:
612:
609:
604:Brenner tumors
593:Brenner tumour
585:
582:
577:
574:
550:
547:
541:
538:
537:
536:
535:
534:
531:
528:
520:
517:
508:
505:
491:
488:
470:
467:
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459:
456:
453:
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430:
415:
414:
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406:
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398:
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384:
381:
380:
379:
378:
377:
370:
364:
361:
355:
352:
334:
327:
315:
312:
306:The chance of
304:
303:
300:
297:
290:
289:
286:
283:
280:
273:
270:
256:
236:Main article:
233:
230:
152:ovarian cancer
144:Ovarian tumors
136:
135:Classification
133:
124:ovarian cancer
116:fallopian tube
73:
72:
67:
61:
60:
44:
43:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2060:
2049:
2046:
2045:
2043:
2028:
2025:
2023:
2020:
2018:
2015:
2013:
2010:
2008:
2005:
2003:
2000:
1999:
1997:
1995:
1991:
1985:
1984:Vaginal cysts
1982:
1980:
1977:
1975:
1972:
1970:
1967:
1965:
1962:
1961:
1959:
1957:
1953:
1943:
1940:
1938:
1935:
1934:
1932:
1928:
1922:
1919:
1917:
1914:
1913:
1911:
1909:
1905:
1899:
1896:
1894:
1891:
1889:
1886:
1884:
1881:
1879:
1876:
1875:
1873:
1871:
1867:
1861:
1858:
1856:
1853:
1851:
1848:
1846:
1843:
1842:
1840:
1838:
1834:
1828:
1825:
1823:
1820:
1818:
1815:
1814:
1812:
1810:
1806:
1803:
1801:
1797:
1787:
1784:
1783:
1781:
1779:
1775:
1765:
1762:
1761:
1759:
1757:
1753:
1745:
1742:
1740:
1739:Struma ovarii
1736:
1733:
1731:
1728:
1726:
1723:
1721:
1718:
1717:
1716:
1713:
1711:
1708:
1707:
1705:
1703:
1699:
1693:
1690:
1688:
1685:
1683:
1680:
1678:
1675:
1673:
1670:
1668:
1665:
1663:
1660:
1659:
1657:
1655:
1651:
1641:
1638:
1636:
1633:
1631:
1628:
1627:
1624:
1618:
1615:
1611:
1608:
1607:
1606:
1603:
1601:
1598:
1596:
1593:
1592:
1590:
1586:
1583:
1581:
1580:stromal tumor
1574:
1570:
1567:
1565:
1561:
1558:
1556:
1552:
1548:
1544:
1537:
1532:
1530:
1525:
1523:
1518:
1517:
1514:
1508:
1505:
1503:
1500:
1498:
1495:
1494:
1484:
1480:
1479:
1475:
1473:
1469:
1465:
1464:
1460:
1456:
1454:
1450:
1446:
1445:
1441:
1437:
1436:
1433:
1428:
1424:
1417:
1411:
1405:
1401:
1400:
1394:
1393:
1389:
1380:
1376:
1371:
1366:
1363:(2): 151–66.
1362:
1358:
1354:
1347:
1345:
1343:
1339:
1334:
1330:
1326:
1322:
1318:
1314:
1306:
1303:
1298:
1294:
1290:
1284:
1281:
1276:
1272:
1267:
1262:
1258:
1254:
1250:
1246:
1242:
1235:
1232:
1227:
1223:
1218:
1213:
1209:
1205:
1201:
1197:
1190:
1187:
1182:
1178:
1173:
1168:
1164:
1160:
1157:(4): 139–42.
1156:
1152:
1148:
1141:
1139:
1137:
1133:
1128:
1126:9781118655344
1122:
1118:
1114:
1110:
1103:
1101:
1099:
1095:
1091:
1086:
1083:
1078:
1072:
1068:
1061:
1058:
1055:
1048:
1044:
1039:
1034:
1030:
1026:
1022:
1018:
1014:
1010:
1006:
999:
997:
993:
988:
984:
979:
974:
970:
966:
961:
956:
952:
948:
944:
935:
931:
926:
921:
917:
913:
909:
901:
898:
895:
891:
887:
881:
878:
872:
869:
863:
860:
854:
851:
845:
842:
837:
831:
827:
820:
817:
814:
810:
806:
800:
797:
791:
788:
781:
778:
772:
769:
765:
759:
756:
751:
750:
742:
735:
733:
729:
722:
720:
718:
714:
710:
703:
701:
699:
695:
691:
687:
679:
677:
675:
671:
667:
663:
659:
655:
651:
646:
642:
640:
632:
630:
626:
624:
619:
617:
610:
608:
605:
598:
597:H&E stain
594:
590:
584:Brenner tumor
583:
581:
575:
573:
570:
563:
562:H&E stain
559:
555:
548:
546:
539:
532:
529:
526:
525:
523:
522:
518:
516:
513:
506:
504:
502:
497:
489:
487:
485:
481:
476:
468:
463:
460:
457:
454:
451:
450:
449:
447:
438:
431:
429:
426:
424:
420:
410:
409:
407:
402:
399:
396:
393:
392:
390:
389:
388:
382:
375:
371:
368:
365:
362:
359:
358:
356:
353:
350:
347:
343:
339:
335:
332:
328:
325:
322:
318:
317:
313:
311:
309:
301:
298:
295:
294:
293:
287:
284:
281:
278:
274:
271:
268:
264:
260:
257:
254:
250:
249:
244:
239:
232:Serous tumors
231:
229:
227:
223:
219:
215:
211:
206:
204:
200:
196:
192:
189:
185:
181:
177:
169:
165:
160:
153:
149:
145:
141:
134:
132:
129:
125:
121:
117:
113:
110:
106:
102:
98:
94:
90:
86:
83:
79:
71:
68:
66:
62:
58:
57:H&E stain
54:
53:Brenner tumor
50:
45:
41:
36:
31:
19:
1710:Dysgerminoma
1577:
1476:
1457:
1438:
1398:
1360:
1356:
1319:(4): 982–6.
1316:
1312:
1305:
1297:the original
1292:
1283:
1248:
1244:
1234:
1199:
1189:
1154:
1150:
1108:
1085:
1066:
1060:
1012:
1008:
950:
946:
915:
911:
900:
885:
880:
871:
862:
853:
844:
825:
819:
804:
799:
790:
780:
771:
758:
748:
717:oophorectomy
707:
683:
672:drug with a
654:chemotherapy
647:
643:
636:
627:
620:
614:
602:
579:
567:
543:
510:
493:
474:
472:
444:
427:
416:
386:
305:
296:cystic areas
291:
238:Serous tumor
218:endometrioid
207:
191:pathological
173:
167:
150:and risk of
119:
87:that may be
77:
76:
1837:Endometrium
692:(33%), the
658:intravenous
441:epithelium.
188:Microscopic
112:endometrial
1827:Adenomyoma
1809:Myometrium
723:References
713:borderline
686:metastasis
680:Metastases
668:include a
558:Micrograph
346:epithelial
324:epithelial
308:malignancy
263:borderline
222:clear cell
107:) or from
105:peritoneum
103:(modified
49:micrograph
1702:Germ cell
1029:2050-0904
969:2090-6781
934:2091-0908
709:Fertility
660:(IV) and
633:Treatment
576:Prognosis
540:Prognosis
519:Pathology
490:Prognosis
469:Pathology
383:Prognosis
336:the term
314:Pathology
267:malignant
253:abdominal
203:malignant
184:papillary
148:incidence
97:Neoplasms
93:malignant
85:neoplasms
65:Specialty
2042:Category
2007:Melanoma
1908:Placenta
1735:Teratoma
1379:23242913
1333:11844820
1275:23835762
1226:24142521
1181:24371647
1047:29744056
987:23082264
688:are the
670:platinum
321:ciliated
214:mucinous
70:Oncology
1930:General
1756:Fibroma
1687:Luteoma
1677:Thecoma
1564:Ovaries
1483:C538090
1390:Sources
1266:6457816
1217:6457824
1172:3861231
1038:5930217
978:3469088
953:: 1–3.
255:cavity.
226:brenner
109:ectopic
82:ovarian
1956:Vagina
1870:Cervix
1800:Uterus
1555:Adnexa
1543:Tumors
1406:
1377:
1331:
1273:
1263:
1224:
1214:
1179:
1169:
1123:
1073:
1045:
1035:
1027:
985:
975:
967:
932:
832:
700:(3%).
674:taxane
338:serous
331:serous
265:, and
259:Benign
224:, and
210:serous
195:benign
180:stroma
128:CA-125
89:benign
1994:Vulva
744:(PDF)
698:lungs
694:liver
333:fluid
326:cells
201:, or
51:of a
1588:CMS:
1478:MeSH
1463:9-CM
1404:ISBN
1375:PMID
1329:PMID
1271:PMID
1249:2016
1222:PMID
1177:PMID
1121:ISBN
1071:ISBN
1043:PMID
1025:ISSN
983:PMID
965:ISSN
951:2012
930:ISSN
830:ISBN
417:The
349:cell
342:cyst
197:, a
2002:SCC
1888:SCC
1472:220
1468:183
1459:ICD
1453:D27
1449:C56
1440:ICD
1365:doi
1321:doi
1261:PMC
1253:doi
1212:PMC
1204:doi
1167:PMC
1159:doi
1113:doi
1033:PMC
1017:doi
973:PMC
955:doi
920:doi
890:doi
809:doi
421:of
146:by
114:or
91:or
2044::
1481::
1470:,
1466::
1451:,
1447::
1444:10
1373:.
1361:19
1359:.
1355:.
1341:^
1327:.
1317:20
1315:.
1291:.
1269:.
1259:.
1247:.
1243:.
1220:.
1210:.
1198:.
1175:.
1165:.
1153:.
1149:.
1135:^
1119:.
1097:^
1052:-
1041:.
1031:.
1023:.
1011:.
1007:.
995:^
981:.
971:.
963:.
949:.
945:.
928:.
914:.
910:.
904:-
731:^
676:.
641:.
595:.
448::
261:,
220:,
216:,
212:,
166:.
95:.
1737:/
1575:/
1535:e
1528:t
1521:v
1461:-
1442:-
1432:D
1412:.
1381:.
1367::
1335:.
1323::
1277:.
1255::
1228:.
1206::
1183:.
1161::
1155:2
1129:.
1115::
1079:.
1049:.
1019::
1013:6
989:.
957::
936:.
922::
916:4
892::
838:.
811::
599:.
564:.
59:.
20:)
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